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Pig

" in MedChemExpress (MCE) Product Catalog:

388

Inhibitors & Agonists

2

Fluorescent Dye

7

Biochemical Assay Reagents

45

Peptides

2

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41

Natural
Products

70

Recombinant Proteins

18

Isotope-Labeled Compounds

16

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1015

    Vasoactive Intestinal Peptide, guinea Pig

    PACAP Receptor Neurological Disease Metabolic Disease
    VIP Guinea pig (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function .
    VIP(Guinea pig)
  • HY-114164C

    Protease Activated Receptor (PAR) Inflammation/Immunology
    Thrombin, Pig blood is a key enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin. Thrombin, Pig blood activates platelet activation, endothelial cell function, and inflammatory responses by binding to PAR-1 and PAR-4, which triggers G protein-coupled signaling pathways. Thrombin, Pig blood holds promise for research in coagulation and inflammation fields .
    Thrombin, Pig blood
  • HY-B2162C

    Chondroitin polysulfate sulfate (from Pig)

    Biochemical Assay Reagents Others
    Chondroitin sulfate from Pig is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Chondroitin sulfate (from pig)
  • HY-NP036

    Biochemical Assay Reagents Others
    Pig Insulin-PE is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Pig Insulin-PE
  • HY-RS10501

    Small Interfering RNA (siRNA) Others

    PIGS Human Pre-designed siRNA Set A contains three designed siRNAs for PIGS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PIGS Human Pre-designed siRNA Set A
    PIGS Human Pre-designed siRNA Set A
  • HY-P3629

    Leumorphin (Pig)

    Opioid Receptor Neurological Disease Inflammation/Immunology
    Dynorphin B 29 (Leumorphin) (pig) is a petide. Dynorphin B 29 (pig) can interact with multiple receptors in the brain, as well as in isolated tissue systems. Dynorphin B 29 (pig) can be used for the research of immunoreaction .
    Dynorphin B 29 (pig)
  • HY-P2703

    Neuropeptide Y Receptor Metabolic Disease Endocrinology
    Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. Peptide YY (pig) decreases appetite and food-intake by activation of the Y2 receptor. Peptide YY (pig) is present mainly in pancreatic endocrine cells with effect on both intestinal motility and the cardiovascular system .
    Peptide YY (pig)
  • HY-P1015A

    Vasoactive Intestinal Peptide, guinea Pig TFA

    PACAP Receptor Neurological Disease Metabolic Disease
    VIP Guinea pig TFA (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function .
    VIP(Guinea pig) TFA
  • HY-P2841

    Elastin

    Biochemical Assay Reagents Others
    Elastin from pig (Elastin) is a key matrix protein that imparts elasticity to organs and tissues. Elastin from pig is a stable, insoluble protein, and utilized in biomaterial for human tissue repairment .
    Elastin from pig
  • HY-E70197

    μ-Calpain

    Cathepsin Others
    Calpain-1 (pig) (μ-Calpain) is an intracellular Ca 2+-regulated cysteine protease. Calpain-1 (pig) exhibits neuroprotective effect .
    Calpain-1 (pig)
  • HY-P2807J

    Lactate Dehydrogenase Metabolic Disease
    L-Lactate Dehydrogenase (L-LDH), pig muscle is an L-lactate dehydrogenase found in pig muscle, mainly present in anaerobic tissues (skeletal muscle, red blood cells). L-Lactate Dehydrogenase (L-LDH), pig muscle can interact with acidic liposomes at low pH, causing protein to adsorb onto the liposomes and inhibit enzyme activity. The IC50 values for L-Lactate Dehydrogenase (L-LDH), pig muscle are 0.05 μM for cardiolipin and 1.3 μM for phosphatidylserine liposomes .
    L-Lactate Dehydrogenase (L-LDH), pig muscle
  • HY-P2289

    pBD-1

    Bacterial Infection
    β-defesin 1 (pig) (pBD-1) is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs .
    β-defesin 1 (pig)
  • HY-P2747

    Aconitase

    Biochemical Assay Reagents Others
    Aconitate hydratase, pig heart is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Aconitate hydratase, pig heart
  • HY-P2289A

    pBD-1 TFA

    Bacterial Infection
    β-defesin 1 (pig) (pBD-1) TFA is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) TFA has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs .
    β-defesin 1 (pig) (TFA)
  • HY-P2831
    Esterase, pig liver
    2 Publications Verification

    CESs

    Endogenous Metabolite Metabolic Disease
    Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
    Esterase, pig liver
  • HY-113442A

    Endogenous Metabolite Inflammation/Immunology
    6-trans-leukotriene B4 is a neutrophil chemotaxin in the guinea pig dermis .
    6-trans-Leukotriene B4
  • HY-103296

    Bradykinin Receptor Endocrinology
    Bombinakinin M is a bradykinin receptor agonist with contractile activity in the guinea pig ileum .
    Bombinakinin M
  • HY-RS16302

    Small Interfering RNA (siRNA) Metabolic Disease

    PKD2 Pig Pre-designed siRNA Set A contains three designed siRNAs for PKD2 gene (Pig), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Components

    PKD2 siRNA-1: 5 nmol (HPLC)

    PKD2 siRNA-2: 5 nmol (HPLC)

    PKD2 siRNA-3: 5 nmol (HPLC)

    siRNA Negative Control: 5 nmol (HPLC)

    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

    GAPDH siRNA Positive Control: 5 nmol (HPLC)

    PKD2 Pig Pre-designed siRNA Set A
    PKD2 Pig Pre-designed siRNA Set A
  • HY-136831

    QMPB

    Leukotriene Receptor Inflammation/Immunology
    SR2640 is a highly efficient and selective LTD4/LTE4 antagonist that can specifically inhibit the smooth muscle contractions induced by LTD4 in the guinea pig ileum and trachea in a concentration-dependent manner, without affecting the contractions caused by histamine. SR2640 can concentration-dependently prevent the binding of 0.4 nM [3H] LTD4 to membrane receptors in guinea pig lung tissue, with an IC50 of 23 nM. SR2640 can shift the dose-response curve for bronchoconstriction induced by intravenous LTD4 in guinea pigs to the right, and the extent of this shift is positively correlated with the dose of SR2640 administered. SR2640 can be used in asthma research .
    SR2640
  • HY-120688

    5-HT Receptor Neurological Disease
    L-772405 is a selective 5-HT1D receptor agonist with the Ki values of 318, 29 and > 1000 nM aganist guinea pig 5-HT1B receptor, guinea pig 5-HT1D receptor and rat 5-HT rransporter, respectively. L-772405 decreases the potassium-induced outflow of 5-HT with an IC50 value of 240 nM .
    L-772405
  • HY-113781

    Adrenergic Receptor Metabolic Disease
    Ractopamine is a potent β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine is linked to protein metabolism. Ractopamine is structurally similar to the natural catecholamines epinephrine and norepinephrine, and binds with high affinity to βAR in pig adipose and muscle tissue. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs .
    Ractopamine
  • HY-147014

    CMV Orthopoxvirus Infection
    Cyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model .
    Cyclic HPMPC
  • HY-118674

    Calcium Channel Cardiovascular Disease
    AK-2-38, a Nifedipine (HY-B0284) analogue, is a calcium channel antagonist. AK-2-38 also has partial agonist effects on isolated guinea pig left atrium .
    AK-2-38
  • HY-P2291

    Bacterial Inflammation/Immunology
    Beta-defensin 103 isoform X1, pig is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens .
    Beta-defensin 103 isoform X1, pig
  • HY-W754020

    Histamine Receptor Others
    Elbanizine inhibits histamine, bradykinin, histamin-release from rat mast cells (IC50 of 0.26 μM) and the IgE-mediated passive cutaneous anaphylaxis (PCA) reaction. Elbanizine exhibits antiallergic and antiasthmatic in guinea pig model .
    Elbanizine
  • HY-116033

    Ser/Thr Protease Inflammation/Immunology
    BMS-363131 is a selective inhibitor for tryptase, with an IC50 <1.7 nM. BMS-363131 is hydrolytic stable at pH=7 and pH=9. BMS-363131 attenuates the astham in a guinea pig model .
    BMS-363131
  • HY-15718B

    PST2744 oxalate

    Na+/K+ ATPase Cardiovascular Disease
    Istaroxime oxalate (PST2744 oxalate) is the oxalate form of Istaroxime (HY-15718). Istaroxime oxalate is is an inotropic agent, that inhibits Na +/K +-ATPase with an IC50 of 0.11 μM. Istaroxime oxalate increases force of contraction in guinea pig atria and twitch amplitude in isolated guinea pig myocytes without causing lethal arrhythmias .
    Istaroxime oxalate
  • HY-NP015

    Bacterial Infection
    SLT/SLT-IIe (O139) protein is a cytotoxin that can be isolated from enterotoxigenic E. coli (ETEC). SLT/SLT-IIe (O139) protein causes edema in pigs .
    SLT/SLT-IIe (O139) protein
  • HY-P10768

    PACAP Receptor Neurological Disease
    Ro 25-1553 is a 31 amino acid vasoactive intestinal peptide (VIP) analog, that acts as an agonist for VIP2 receptor (VPAC2 receptor). Ro 25-1553 exhibits a bronchodilator effect in nerve-induced or Carbachol (HY-B1208)-induced tracheal smooth muscle contraction in guinea pig model .
    Ro 25-1553
  • HY-P2291A

    Bacterial Inflammation/Immunology
    Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens .
    Beta-defensin 103 isoform X1, pig TFA
  • HY-P4841

    GLP Receptor Others
    GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) is a biotinylated GLP-1 fragment, corresponding to the 7-36 sequence of GLP-1.
    GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat)
  • HY-E70437

    Tissue-type transglutaminase; TG2; TGase 2

    Biochemical Assay Reagents Others
    Guinea pig liver transglutaminase (Tissue-type transglutaminase) is an exoenzyme. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .
    Guinea pig liver transglutaminase
  • HY-101390

    (S)-Niguldipine hydrochloride

    Calcium Channel Cardiovascular Disease
    (+)-Niguldipine hydrochloride is an antagonist for calcium channel. (+)-Niguldipine hydrochloride produces vasodilation by blocking calcium channels and reducing the transmembrane influx of calcium ions. (+)-Niguldipine hydrochloride inhibits U-46619 (HY-108566)-induced coronary vasoconstriction in guinea pig Langendorff heart with pID50 of 11.37, binds to calcium channel on guinea pig skeletal muscle membrane with Ki of 9.75, and lowers the blood pressure in spontaneously hypertensive rat with pED30 of 7.1. (+)-Niguldipine hydrochloride ameliorates cardiovascular diseases such as hypertension, angina pectoris and arrhythmias .
    (+)-Niguldipine hydrochloride
  • HY-N3167

    Nucleoside Antimetabolite/Analog Cardiovascular Disease
    Nyasicoside is a norlignan glucosides that can be isolated from Curculigo capitulate. Nyasicoside has potent activity against ouabain-induced arrhythmia in the heart preparations of guinea pig .
    Nyasicoside
  • HY-167902

    5-HT Receptor Metabolic Disease
    YM-31636 free base is an orally active, potent and selective 5-HT3 receptor agonist with a Ki value of 0.2 nM. YM-31636 free base induces contraction of isolated guinea pig distal colon. YM-31636 free base induces tachycardia with the relative intrinsic activity of approximately 0.23 in isolated guinea pig right atrium. YM-31636 free base is promising for research of constipation .
    YM-31636 free base
  • HY-164650

    Sch 37224

    Leukotriene Receptor Inflammation/Immunology
    Pirodomast (Sch 37224) is a leukotriene formation inhibitor. Pirodomast inhibits LTD4 andthromboxane B2 release by anaphylactic guinea pig lung with the IC50 values of 3.9 and 1.9 μM, respectively. Pirodomast can be used for study of asthma .
    Pirodomast
  • HY-101590A

    L 16726 dihydrochloride

    Parasite Infection
    Symetine dihydrochloride (L 16726 dihydrochloride) is the dihydrochloride form of Symetine (HY-101590). Symetine dihydrochloride exhibits antiprotozoal activity aginst Entamoeba histolytica, and ameliorates the amebic liver abscess in guinea pig model .
    Symetine dihydrochloride
  • HY-164010

    Histamine Receptor Dopamine Receptor Adrenergic Receptor Sigma Receptor Cardiovascular Disease Inflammation/Immunology
    SUN-1334H free base is an orally active inhibitor for histamine H1 receptor, with an IC50 of 20.3 nM and Ki of 9.7 nM. SUN-1334H free base inhibits histamine-induced contractions of isolated guinea-pig ileum with an IC50 of 0.198 μM. SUN-1334H free base inhibits histamine-induced bronchoconstriction in guinea pigs, histamine-induced skin wheals in beagle dogs, and ovalbumin-induced rhinitis in guinea pigs .
    SUN-1334H free base
  • HY-117706

    Leukotriene Receptor Inflammation/Immunology
    LY 292728 is a potent leukotriene B4 (LTB4) receptor antagonist. LY 292728 binds to human neutrophils with a Ki of 0.47 nM and binds to guinea pig lung membranes with a Ki of 0.04 nM .
    LY 292728
  • HY-114724

    Histamine Receptor Inflammation/Immunology
    HSR-609 is an orally active amphoteric antiallergic agent. HSR-609 has a high affinity for histamine H1-receptor in the guinea pig cerebral cortex. HSR-609 inhibits allergic airway hyperresponsiveness to Acetylcholine. HSR-609 shows poor ability to penetrate into the CNS in mice and guinea pigs .
    HSR-609
  • HY-113465A

    Endogenous Metabolite Inflammation/Immunology
    11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum .
    11-trans Leukotriene E4
  • HY-160932

    Adrenergic Receptor Endocrinology
    RS-15385-198 is the enantiomer of Delequamine (RS-15385-197) (HY-106874). RS-15385-198 exhibits a pKi of 6.32 for α2-adrenoceptors in the rat cortex. RS-15385-198 is an antagonist for UK-14304 (HY-B0659) in the rat vas deferens and in the guinea-pig ileum .
    RS-15385-198
  • HY-120476

    TRP Channel Neurological Disease Inflammation/Immunology
    JNJ-39729209 is an antagonist for transient receptor potential vanilloid 1 (TRPV1) with pIC50 of 7.9, 8.5, 7.9 and 7.7 for TRPV1 from human, rat, canine and guinea pig. JNJ-39729209 inhibits Capsaicin (HY-10448)-induced hypotension and inhibit thereby hypothermia. JNJ-39729209 exhibits anti-inflammatory and analgesic activities in Carrageenan (HY-125474)- and CFA (HY-153808)-induced thermal hyperalgesia rat models. JNJ-39729209 exhibits anti-cough effects in guinea pigs .
    JNJ-39729209
  • HY-169472

    Drug Derivative Cardiovascular Disease
    11-Deoxy prostaglandin F1β is a synthetic analog of PGF1β. 11-Deoxy prostaglandin F1β exhibits vasodepressor and bronchodilator activities in guinea pigs .
    11-Deoxy prostaglandin F1β
  • HY-117255

    Potassium Channel Others
    ZM260384 is a KATP channel opener that accelerates metabolism and inhibits the decline of guinea pig isolated diaphragm function, thereby affecting muscle contraction. ZM260384 can be used to study muscle function under hypoxic conditions .
    ZM260384
  • HY-N12108

    Phosphatase Infection Inflammation/Immunology Cancer
    Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE) .
    Forphenicine
  • HY-P10599

    Neurokinin Receptor Neurological Disease
    Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a Ki value of 0.9 nM for rat submandibular gland NK-1 receptor and 2 nM for hamster bladder NK-2 receptor. Scyliorhinin I has the ability to contract the longitudinal muscles of the guinea pig ileum .
    Scyliorhinin I
  • HY-123206

    5-HT Receptor Inflammation/Immunology
    R-96544 (free base) is a potent, selective and competitive 5-HT2 receptor antagonist. R-96544 (free base) inhibits platelet aggregation induced by serotonin, and inhibits 5-HT2A receptor-mediated contraction of guinea pig trachea .
    R-96544 free base
  • HY-118463

    Neurokinin Receptor Neurological Disease
    Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .
    Benzomalvin A
  • HY-112739

    Leukotriene Receptor Inflammation/Immunology
    SC-41930 is a orally active eukotriene-B4 receptor antagonist. SC-41930 alleviates inflammation in guinea pig acetic acid-induced colonic inflammation model .
    SC-41930

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