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DMTMM  (Synonyms: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride)

Cat. No.: HY-Y1168 Purity: 99.53%
Handling Instructions Technical Support

DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials.

For research use only. We do not sell to patients.

DMTMM Chemical Structure

DMTMM Chemical Structure

CAS No. : 3945-69-5

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials[1][2][3][4][5][6][7][8].

In Vitro

NorHA hydrogels synthesized by DMTMM can promote cell (hMSCs and bCHs) spreading[2].
CLP-PEG-MPC hydrogels prepared by DMTMM support the proliferation of human corneal epithelial cells (HCEC)[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

CLP-PEG-MPC implants prepared with the involvement of DMTMM can reduce corneal swelling, haze, and neovascularization, promote nerve regeneration and recovery of corneal sensation in the corneal stroma in mini-pigs[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

276.72

Formula

C10H17ClN4O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[N+]1(C2=NC(OC)=NC(OC)=N2)CCOCC1.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (180.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6137 mL 18.0685 mL 36.1371 mL
5 mM 0.7227 mL 3.6137 mL 7.2274 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.77%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6137 mL 18.0685 mL 36.1371 mL 90.3427 mL
5 mM 0.7227 mL 3.6137 mL 7.2274 mL 18.0685 mL
10 mM 0.3614 mL 1.8069 mL 3.6137 mL 9.0343 mL
15 mM 0.2409 mL 1.2046 mL 2.4091 mL 6.0228 mL
20 mM 0.1807 mL 0.9034 mL 1.8069 mL 4.5171 mL
25 mM 0.1445 mL 0.7227 mL 1.4455 mL 3.6137 mL
30 mM 0.1205 mL 0.6023 mL 1.2046 mL 3.0114 mL
40 mM 0.0903 mL 0.4517 mL 0.9034 mL 2.2586 mL
50 mM 0.0723 mL 0.3614 mL 0.7227 mL 1.8069 mL
60 mM 0.0602 mL 0.3011 mL 0.6023 mL 1.5057 mL
80 mM 0.0452 mL 0.2259 mL 0.4517 mL 1.1293 mL
100 mM 0.0361 mL 0.1807 mL 0.3614 mL 0.9034 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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