2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. SB 271046 Hydrochloride (Standard)

SB 271046 Hydrochloride (Standard) 

Cat. No.: HY-14336AR Purity: ≥98%
Handling Instructions Technical Support

SB 271046 (Hydrochloride) (Standard) is the analytical standard of SB 271046 (Hydrochloride). This product is intended for research and analytical applications. SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).

For research use only. We do not sell to patients.

SB 271046 Hydrochloride (Standard) Chemical Structure

SB 271046 Hydrochloride (Standard) Chemical Structure

CAS No. : 209481-24-3

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Description

SB 271046 (Hydrochloride) (Standard) is the analytical standard of SB 271046 (Hydrochloride). This product is intended for research and analytical applications. SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).

Molecular Weight

488.45

Formula

C20H23Cl2N3O3S2
CAS No.
SMILES

ClC1=CC2=C(C=C1)SC(S(=O)(NC3=CC=C(C(N4CCNCC4)=C3)OC)=O)=C2C.[H]Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SB 271046 Hydrochloride (Standard) Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB 271046 Hydrochloride (Standard)209481-24-35-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorselectiveoralchannelsanticonvulsantMESTtestInhibitorinhibitorinhibit

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