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D4

" in MedChemExpress (MCE) Product Catalog:

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Isotope-Labeled Compounds

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Oligonucleotides

D4-abiraterone Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite	Androgen Receptor Cytochrome P450	Cancer
D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor.

D-4-Hydroxyphenylglycine D-(-)-4-Hydroxyphenylglycine; 4-Hydroxy-D-phenylglycine	Antibiotic	Others
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

APP-018 D-4F	Apolipoprotein	Cardiovascular Disease
APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases .

Stavudine 3 Publications Verification D4T	Reverse Transcriptase HIV Nucleoside Antimetabolite/Analog NOD-like Receptor (NLR) Autophagy Apoptosis	Infection
Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis ^[4].

D-4-Hydroxyphenylglycine (Standard) D-(-)-4-Hydroxyphenylglycine (Standard); 4-Hydroxy-D-phenylglycine (Standard)	Drug Intermediate Reference Standards	Others
D-4-Hydroxyphenylglycine (Standard) is the analytical standard of D-4-Hydroxyphenylglycine. This product is intended for research and analytical applications. D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

D4R antagonist-2	Dopamine Receptor	Neurological Disease
D4R antagonist-2 (compound 33) is a *D4R* antagonist. D4R antagonist-2 has a IC₅₀ value of 210 nM, and a Ki value of 59 nM for D4R. D4R antagonist-2 can be used in the Parkinson's disease research .

D4R agonist-1	Dopamine Receptor	Neurological Disease
D4R agonist-1 (Compound 16f) is a *D4R* partial agonist (K_i: 2.2 nM). D4R agonist-1 is metabolically stable in rat and human liver microsomes. D4R agonist-1 can be used for research of neuropsychiatric disorders .

D-4-77	SARS-CoV Virus Protease	Infection
D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro with an IC₅₀ value of 0.95 μM. D-4-77 has antiviral active with an EC₅₀ value of 0.49 μM. D-4-77 suppresses SARS-CoV-2 Mpro -induced antagonism of the host NF-κB innate immune response .

D4R antagonist-1	Dopamine Receptor	Neurological Disease
D4R antagonist-1 is a potent and selective *D4R* antagonist with an IC₅₀ of 6.87 µM. D4R antagonist-1 has the potential for the research of Parkinson’s disease .

D4R antagonis-2	Dopamine Receptor	Neurological Disease
D4R antagonist-2 is a potent and selective *D4R* antagonist with an IC₅₀ of 6.52 µM. D4R antagonist-2 displays very favorable in vitro PK parameters and has good brain penetration. D4R antagonist-2 has the potential for the research of Parkinson’s disease .

Stavudine sodium D4T sodium	Reverse Transcriptase HIV Nucleoside Antimetabolite/Analog NOD-like Receptor (NLR) Autophagy Apoptosis	Infection
Stavudine (d4T) sodium is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine sodium has activity against HIV-1 and HIV-2. Stavudine sodium also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine sodium reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine sodium induces apoptosis ^[4].

Stavudine (Standard) D4T (Standard)	Reference Standards Reverse Transcriptase HIV Nucleoside Antimetabolite/Analog NOD-like Receptor (NLR) Autophagy Apoptosis	Infection
Stavudine (Standard) is the analytical standard of Stavudine. This product is intended for research and analytical applications. Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis ^[4].

Dopamine D4 receptor antagonist-1	Dopamine Receptor	Neurological Disease
Dopamine D4 receptor antagonist-1 is a selective *DRD4* antagonists, with a K_i of 9.0 nM for *Hd4.2*. Dopamine D4 receptor antagonist-1 can be used in study of schizophrenia .

Leukotriene D4 1 Publications Verification	Drug Metabolite Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability .

Cerexin D4	Bacterial	Infection
Cerexin D4 has anti-Gram-positive bacterial activity .

Vitamin D4 3 Publications Verification 22-Dihydroergocalciferol	VD/VDR	Metabolic Disease
Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol .

Dopamine D4 receptor ligand 2	Dopamine Receptor	Neurological Disease
Dopamine D4 receptor ligand 2 (compound 17) is a potent and selective dopamine D4 ligand with IC₅₀ values of 0.057, >1000, 220, 270 nM for D4, D2, 5-HT1A, α1, respectively .

Resolvin D4 RvD4	Bacterial	Inflammation/Immunology
Resolvin D4 (RvD4), a specialized proresolving mediator, can be produced in bioactive levels during S. aureus infection .

Dopamine D4 receptor ligand 3	Dopamine Receptor Reactive Oxygen Species (ROS)	Cancer
Dopamine D4 receptor ligand 3 (Compound 16) is a dopamine D4 receptor (D4R) antagonist (pK_i: 8.86). Dopamine D4 receptor ligand 3 has pIC₅₀ values of 5.78, 5.55, and 6.17 for Go, Gi, and βArr2 sensors in HEK-293T cells, respectively. Dopamine D4 receptor ligand 3 inhibits the viability of three human glioma cell lines, U87 MG, T98G, and U251 MG. Dopamine D4 receptor ligand 3 induces ROS production and mitochondrial dysfunction in glioma cells .

14,15-Leukotriene D4 14,15-LTD4; Eoxin D4	Endogenous Metabolite	Inflammation/Immunology
14,15-Leukotriene D4 (14,15-LTD4) is a leukotriene that producted by eosinophils with Arachidonic acid (HY-109590), and through the 15-lipoxygenase-1 pathway .

17(R)-Resolvin D4 17(R)-RvD4	Bacterial	Inflammation/Immunology
17(R)-Resolvin D4 (17(R)-RvD4) is the R-enantiomer of Resolvin D4. Resolvin D4 (RvD4), a specialized proresolving mediator, can be produced in bioactive levels during S. aureus infection .

4-Acetamidobenzene-1-sulfonyl chloride D4	Isotope-Labeled Compounds	Others
4-Acetamidobenzene-1-sulfonyl chloride d₄ is the deuterium labeled 4-Acetamidobenzene-1-sulfonyl chloride .

Pitavastatin D4 NK-104 d₄	HMG-CoA Reductase (HMGCR) Autophagy Mitophagy Apoptosis	Metabolic Disease Cancer
Pitavastatin-d₄ is deuterium labeled Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor.

Rupatadine-d4 fumarate UR-12592 D4 fumarate	Isotope-Labeled Compounds Histamine Receptor Autophagy	Inflammation/Immunology
Rupatadine-d₄ fumarate is a deuterium labeled Rupatadine fumarate. Rupatadine Fumarate (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with K_i values of 0.55/0.1 μM (rabbit platelet membranes/guinea pig cerebellum membranes) .

Etravirine D4 TMC-125 d₄; R-165335 d₄	Reverse Transcriptase HIV	Infection
Etravirine-d₄ is the deuterium labeled Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

11-trans Leukotriene D4 11-trans LTD4	Drug Isomer	Others
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.

Dexmedetomidine-d4 L-tartrate (-d4-major)	Isotope-Labeled Compounds	Others
Dexmedetomidine-d₄ L-tartrate (-d₄-major) is deuterium labeled Dexmedetomidine L-tartrate (-d4-major) .

Picolinafen-d4 (4-Fluorophenyl-d4)	Isotope-Labeled Compounds	Others
Picolinafen-d₄ (4-fluorophenyl-d₄) is the deuterium labeled Picolinafen .

Conivaptan-d4	Isotope-Labeled Compounds	Others
Conivaptan-d4 is deuterium labeled Conivaptan-d4.

(±)-Fluoxetine-d4 Oxalate (trifluoromethylphen-d4-oxy)	Isotope-Labeled Compounds	Others
(±)-Fluoxetine-d₄ Oxalate (trifluoromethylphen-d₄-oxy) is the deuterium labeled (±)-Fluoxetine Oxalate .

Keto Pioglitazone-d4 (M-III-d4)	Isotope-Labeled Compounds	Others
Keto Pioglitazone-d4 (M-III-d4) is the deuterium labeled Keto Pioglitazone (M-III) .

Leukotriene D4-d5	Drug Metabolite Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
Leukotriene D4-d₅ is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.

Imidacloprid impurity 2-d4 hydrochloride	Drug Metabolite Isotope-Labeled Compounds	Others
Imidacloprid impurity 2-d₄ (hydrochloride) is the deuterium labeled Imidacloprid impurity 2-d₄ (hydrochloride) .

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers) .

Phthalic Acid Anhydride-d4	Isotope-Labeled Compounds	Others
Phthalic Acid Anhydride-d₄ is the deuterium labeled Phthalic Acid Anhydride-d₄ .

Desmethyl Erlotinib-d4-1 OSI-420-D4-1 free base; CP-373420-D4-1	Drug Metabolite Isotope-Labeled Compounds	Cancer
Desmethyl Erlotinib-d₄-1 (OSI-420-d₄-1 (free base); CP-373420-d₄-1) is deuterium-labeled Desmethyl Erlotinib (HY-13256A) .

1alpha-Hydroxy VD4 1 Publications Verification 1α-Hydroxy vitamin D4	VD/VDR	Cancer
1alpha-Hydroxy VD4, a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.

Flupirtine-d4 hydrochloride D 9998-D4 hydrochloride	Potassium Channel iGluR	Neurological Disease
Flupirtine-d4 (D 9998-d4) hydrochloride is the deuterium labeled Flupirtine. Flupirtine(D 9998) hydrochloride is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties .

Fananserin RP 62203	5-HT Receptor Dopamine Receptor	Neurological Disease
Fananserin (RP 62203) is an orally bioavailable, potent and selective 5-hydroxytryptamine2 (5-HT₂) receptor antagonist, with a K_i of 0.37 nM for the rat 5-HT_2A receptor. Fananserin also is a selective dopamine D4 receptor antagonist, with a K_i of 2.93 nM for the human dopamine D4 receptor .

Flavoxate-d4 hydrochloride	Isotope-Labeled Compounds mAChR	Neurological Disease
Flavoxate-d₄ hydrochloride (Rec-7-0040-d₄) is the deuterium labeled Flavoxate hydrochloride. Flavoxate Hydrochloride is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic .

6-ECDCA-d4 6α-ethyl Cheodeoxycholic Acid-D4, Obeticholic Acid-d₄	Isotope-Labeled Compounds	Others
6-ECDCA-d₄ (6α-ethyl Cheodeoxycholic Acid-d₄, Obeticholic Acid-d₄) is deuterium labeled 6-ECDCA .

Iloprost-d4	Isotope-Labeled Compounds Prostaglandin Receptor	Endocrinology
Iloprost-d₄ (Ciloprost-d₄) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2 .

Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans)	Isotope-Labeled Compounds	Others
Glimepiride-d₄(phenylethyl-α,α,β,β-d₄)(cis/trans) is the deuterium labeled .

2-Benzothiazolethiol-d4	Isotope-Labeled Compounds	Others
2-Benzothiazolethiol-d4 is the deuterium labeled 2-Benzothiazolethiol-d4 (HY-W653751) .

Methyl tetracosanoate-d4 Methyl lignocerate-D4; Tetracosanoic Acid Methyl Ester-D4	Isotope-Labeled Compounds Others	Metabolic Disease
Methyl tetracosanoate-d₄ (Methyl lignocerate-d₄) is deuterium labeled Methyl tetracosanoate. Methyl tetracosanoate (Methyl lignocerate) is a fatty acid methyl ester with anti-diabetic activity .

4-Chlorobenzoic acid-d4	Isotope-Labeled Compounds	Others
4-Chlorobenzoic acid-d₄ is the deuterium labeled 4-Chlorobenzoic acid-d₄ .

Cat. No.	Product Name

HY-L165

Dopamine Receptor Compound Library

238 compounds

Dopamine receptor (DAR), widely distributed in the brain, plays a key role in regulating motor function, motivation, driving force and cognition. The role of DA is mediated by D1-type (D1, D5) and D2-type receptors (D2S, D2L, D3, D4), which are distributed in presynaptic, postsynaptic and extrasynaptic, projection neurons and interneurons. Each receptor has a different function. D1 and D5 receptors couple with G stimulation sites and activate Adenylyl cyclase. The activation of Adenylyl cyclase leads to the production of the second messenger cAMP, which leads to the production of protein kinase A (PKA), which leads to further transcription in the nucleus. D2 to D4 receptors are coupled to G inhibitory sites to inhibit adenylyl cyclase and activate potassium Ion channel. These receptors utilize phosphorylation cascades or direct membrane interactions to affect the functions of voltage-gated and neurotransmitter-gated channels, cytoplasmic enzymes, and transcription factors. Dopamine receptor plays an important role in daily life.

MCE designs a unique collection of 238 small molecules related to dopamine receptor. It is a good tool for screening drugs from nervous system disease.

Cat. No.	Product Name	Type

HY-112624J

Dextran T4 (MW 4,000)

Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)

Thickeners

Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-34666

trans-D-4-Hydroxyproline

Carbohydrates

trans-D-4-Hydroxyproline is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-109541S1

Colfosceril miristate-d4 DMPC-d₄; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₄	Drug Delivery
Colfosceril miristate-d₄ (DMPC-d₄) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .

HY-W127840

Ethylene-d4-diamine 1,1,2,2-tetradeuterioethane-1,2-diamine-d₄	Biochemical Assay Reagents
Ethylene-d₄-diamine is the deuterium labeled Ethylene-diamine .

Cat. No.	Product Name	Target	Research Area

HY-P6365B

APP-018 D-4F	Apolipoprotein	Cardiovascular Disease
APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases .

HY-W009023

*Fmoc-D-4-Pal-OH*	Amino Acid Derivatives	Others
Fmoc-D-4-Pal-OH is an alanine derivative .

HY-W022404

*H-D-4-Pal-OH.2HCl*	Amino Acid Derivatives	Others
H-D-4-Pal-OH.2HCl is an alanine derivative .

HY-W006937

*Boc-D-(4-fmoc)-aminophenylalanine* Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-fmoc)-OH	Amino Acid Derivatives	Others
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .

HY-P5126

DOTA-LM3 1 Publications Verification	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis . DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P5126A

DOTA-LM3 TFA 1 Publications Verification	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis . DOTA-LM3 (TFA) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P1560

*Allergen Gal d 4* (46-61), chicken** Lysozyme C (46-61) (chicken)	Bacterial	Infection
Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.

HY-P11078

LARLLT	EGFR	Cancer
LARLLT (D4) is an EGFR-binding peptide. LARLLT has the potential for research of EGFR overexpressing cancers, such as lung, ovarian and colorectal cancer .

HY-W009402

*Boc-D-4-Pal-OH*	Amino Acid Derivatives	Others
Boc-D-4-Pal-OH is an alanine derivative .

HY-W044285

*Fmoc-D-4-Aph(cBm)-OH*	Amino Acid Derivatives	Others
Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity .

Cat. No.	Product Name	Target	Research Area

HY-P990144

Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2)	Inhibitory Antibodies	Others
Anti-Mouse/Human VLA-4/CD49d Antibody (PS/2) is a rat-derived IgG2b, κ type antibody inhibitor, targeting to mouse/human VLA-4/CD49d.

HY-P991110

Anti-Mouse CD25 Antibody (7D4)	Interleukin Related	Inflammation/Immunology
Anti-Mouse CD25 Antibody (7D4) is a mouse IgG2 monoclonal antibody that targets CD25. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).

Species:	Human (3) Mouse (1) Cat (1)
Tag:	His (4) SUMO (1) GST (1)
Source:	HEK293 (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P78019

	PLD4 Protein, Human (HEK293, His) 5'-3' exonuclease PLD4; Choline phosphatase 4; Phospholipase D4; PLD 4	Human	HEK293
	PLD4 Protein, a phospholipase, plays a crucial role in immune responses and inflammation. Dysregulation of PLD4 Protein has been associated with autoimmune disorders and inflammatory diseases. Targeting PLD4 Protein may provide potential therapeutic interventions in these conditions by modulating immune responses, suppressing inflammation, and managing related disorders. PLD4 Protein, Human (HEK293, His) is the recombinant human-derived PLD4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71400

	UBE2D4 Protein, Human (GST) Ubiquitin-Conjugating Enzyme E2 D4; HBUCE1; Ubiquitin Carrier Protein D4; Ubiquitin-Protein Ligase D4; UBE2D4; UBCH5D	Human	E. coli
	The UBE2D4 protein is an important ubiquitin-proteasome system component that acts as an E2 ubiquitin-conjugating enzyme, accepting ubiquitin from the E1 complex and catalyzing its covalent attachment to proteins. In vitro, UBE2D4 exhibits multifunctionality by promoting polyubiquitination of all seven ubiquitin Lys residues, possibly favoring polyubiquitination of “Lys-11” and “Lys-48” linkages. UBE2D4 Protein, Human (GST) is the recombinant human-derived UBE2D4 protein, expressed by E. coli , with N-GST labeled tag.

HY-P71573

	*Allergen Fel d 4* Protein, Cat (His-SUMO)** Allergen Fel d 4; allergen Fel d 4	Cat	E. coli
	Allergen Fel d 4 Protein, Cat (His-SUMO) is a recombinant protein with a His-SUMO tag. Fel d 4 is a lipocalin allergen produced by the cat, which binds IgE at relatively high frequency in cat-sensitive individuals.

HY-P77821

	PLD4 Protein, Mouse (HEK293, His) 5'-3' exonuclease PLD4; Choline phosphatase 4; Phospholipase D4; PLD 4	Mouse	HEK293
	PLD4 Protein, with 5'->3' DNA exonuclease activity, efficiently digests single-stranded DNA (ssDNA). It crucially regulates inflammatory cytokine responses by degrading nucleic acids, reducing ssDNA concentrations activating TLR9. Additionally, PLD4 actively participates in the phagocytosis process of activated microglia, emphasizing its role in immune responses. PLD4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLD4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77623

	CD99 Protein, Human (HEK293, His) 12E7; E2 antigen; MIC2; MIC2X; MIC2Y; CD99; HBA71; MSK5X; 12E7; 1110061M03Rik; 2410026K10Rik; D4; pilr-1; Pilr-l; CD99 molecule	Human	HEK293
	The CD99 protein is involved in the important T cell adhesion process and helps red blood cells spontaneously form rosettes. It also contributes to the later stages of leukocyte extravasation, helping leukocytes to overcome the endothelial basement membrane during the immune response. CD99 Protein, Human (HEK293, His) is the recombinant human-derived CD99 protein, expressed by HEK293 , with N-His labeled tag.

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Species
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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82893

	D4 GDI Antibody (YA2638) Rho GDP dissociation inhibitor (GDI) beta; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2	WB, IHC-F, IHC-P, ICC/IF	Human
	D4 GDI Antibody (YA2638) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2638), targeting D4 GDI, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). D4 GDI Antibody (YA2638) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human background.

HY-P86847

	DPF2 Antibody (YA6540) Apoptosis response zinc finger protein antibody; BAF45D antibody; BRG1-associated factor 45D antibody; D4 antibody; D4 zinc and double PHD fingers family 2 antibody; Double PHD fingers 2 antibody; double PHD fingers family 2 antibody; DPF 2 antibody; DPF2 antibody; MGC10180 antibody; Apoptosis response zinc finger protein antibody; BAF45D antibody; BRG1-associated factor 45D antibody; D4 antibody; D4 zinc and double PHD fingers family 2 antibody; Double PHD fingers 2 antibody; double PHD fingers family 2 antibody; DPF 2 antibody; DPF2 antibody; MGC10180 antibody; Protein requiem antibody; REQ antibody; REQU_HUMAN antibody; Requiem antibody; Requiem apoptosis response zinc finger antibody; UBI D4 antibody; ubi-D4 antibody; UBID 4 antibody; UBID4 antibody; zinc and double PHD fingers family 2 antibody; Zinc finger protein ubi D4 antibody; Zinc finger protein ubi-D4 antibody	WB, ICC/IF, IHC-P	Human, Mouse, Rat

HY-P86232

	TBC1D4 Antibody (YA5924) TBC1D4; AS160; KIAA0603; TBC1 domain family member 4; Akt substrate of 160 kDa; AS160	WB, ICC/IF, IP, ELISA	Human, Mouse
	TBC1D4 Antibody (YA5924) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TBC1D4. It can be applicated for WB, ICC/IF, IP, ELISA assays, in the background of human, mouse.

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Cat. No.	Product Name		Classification

HY-13256AS

Desmethyl Erlotinib-d4		Alkynes
Desmethyl Erlotinib-d₄ is the deuterium labeled Desmethyl Erlotinib. Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor . Desmethyl Erlotinib-d₄ is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d₄; Ethynylestradiol-d₄		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151117S

Methylacetylene-d4		Alkynes
Methylacetylene-d₄ is the deuterium labeled Methylacetylene . Methylacetylene-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-143964S

Irbesartan impurity 14-d4		Azide
Irbesartan impurity 14-d₄ is the deuterium labeled Irbesartan impurity 14 . Irbesartan impurity 14-d₄ is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-143963S

Irbesartan impurity 20-d4		Azide
Irbesartan impurity 20-d₄ is the deuterium labeled Irbesartan impurity 20 . Irbesartan impurity 20-d₄ is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-143980S

Losartan impurity 21-d4		Azide
Losartan impurity 21-d₄ is the deuterium labeled Losartan impurity 21 . Losartan impurity 21-d4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-B0390S1

Mestranol-d4		Alkynes
Mestranol-d₄ is the deuterium labeled Mestranol. Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders . Mestranol-d₄ is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-RS28579

Cacna2d4 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Cacna2d4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cacna2d4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS22061

Cacna2d4 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cacna2d4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cacna2d4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15136

TSC22D4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TSC22D4 Human Pre-designed siRNA Set A contains three designed siRNAs for TSC22D4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01804

CACNA2D4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CACNA2D4 Human Pre-designed siRNA Set A contains three designed siRNAs for CACNA2D4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14244

TBC1D4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TBC1D4 Human Pre-designed siRNA Set A contains three designed siRNAs for TBC1D4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09821

OR7D4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
OR7D4 Human Pre-designed siRNA Set A contains three designed siRNAs for OR7D4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03599

DCUN1D4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
DCUN1D4 Human Pre-designed siRNA Set A contains three designed siRNAs for DCUN1D4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12825

SH2D4A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SH2D4A Human Pre-designed siRNA Set A contains three designed siRNAs for SH2D4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS21985

Arhgdib Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Arhgdib Mouse Pre-designed siRNA Set A contains three designed siRNAs for Arhgdib gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02576

CGAS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CGAS Human Pre-designed siRNA Set A contains three designed siRNAs for CGAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17583

Cd99 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cd99 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd99 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS00944

ARHGDIB Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ARHGDIB Human Pre-designed siRNA Set A contains three designed siRNAs for ARHGDIB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-152556

3-Deaza-4’-C-methyluridine		Nucleosides and their Analogs U
3-Deaza-4’-C-methyluridine, 4-Hydroxy-1-β-D-(4-C-methylribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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