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Results for "

acid phosphatase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phosphatase (292) PTEN (4) SHP1 (8) SHP2 (13) 5-HT Receptor (2) Akt (6) Aldose Reductase (1) Amyloid-β (2) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (2) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (28) Apoptosis (42) ATM/ATR (1) Autophagy (13) Bacterial (29) Beta-secretase (1) Biochemical Assay Reagents (32) c-Met/HGFR (1) Calcineurin (1) CaMK (2) Carbamoyl Phosphate Synthetase (CPS) (1) Carbonic Anhydrase (1) Carboxylesterase (CES) (1) Cathepsin (1) CDK (2) Cholinesterase (ChE) (4) Complement System (5) COX (3) Cyclic GMP-AMP Synthase (1) Cyclophilin (4) Cytochrome P450 (1) DNA/RNA Synthesis (3) Dopamine β-hydroxylase (1) Drug Derivative (1) Drug Intermediate (7) EBV (1) EGFR (1) Endogenous Metabolite (30) Enterovirus (1) Epigenetic Reader Domain (1) Epoxide Hydrolase (1) ERK (5) FKBP (5) Fluorescent Dye (12) Fungal (12) Glutathione Peroxidase (2) Glycosidase (4) Hedgehog (1) Histone Methyltransferase (2) HIV (10) HIV Protease (8) HSV (2) IFNAR (1) iGluR (2) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (11) JNK (1) Leukotriene Receptor (1) Liposome (1) Lipoxygenase (1) MAP3K (2) MAP4K (1) Mas-related G-protein-coupled Receptor (MRGPR) (1) MDM-2/p53 (3) mGluR (1) Mitochondrial Metabolism (1) Molecular Glues (4) Monoamine Oxidase (2) NF-κB (3) Notch (1) Nuclear Factor of activated T Cells (NFAT) (1) Nucleoside Antimetabolite/Analog (1) p38 MAPK (2) Parasite (20) PDI (1) PERK (1) Phosphodiesterase (PDE) (1) Phospholipase (3) Phosphorylase (1) PI3K (2) PKA (1) PKC (3) Potassium Channel (2) PPAR (2) Progesterone Receptor (2) PROTACs (1) Protease Activated Receptor (PAR) (1) Raf (2) RANKL/RANK (1) Ras (2) Reactive Oxygen Species (ROS) (6) Reference Standards (18) Reverse Transcriptase (3) SARS-CoV (3) Ser/Thr Protease (2) Sirtuin (3) Somatostatin Receptor (1) STAT (4) Tau Protein (1) Thyroid Hormone Receptor (1) Tie (1) TMV (1) Toll-like Receptor (TLR) (1) Topoisomerase (4) Urea Transporter (1) Wnt (2) α-synuclein (1)
By Research Areas:	Cancer (160) Cardiovascular Disease (15) Endocrinology (12) Infection (64) Inflammation/Immunology (63) Metabolic Disease (94) Neurological Disease (37)
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Oligonucleotides:	Nucleotides and their Analogs (3) A (3) Nucleosides and their Analogs (1) G (1) Phospholipids (1) Antisense Oligonucleotides (2)

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Targets Recommended: Phosphatase PTEN SHP2 Amino acid Transporter Amino Acid Derivatives Amino Acid Decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Amino Acid Oxidase Free Fatty Acid Receptor Fatty Acid Synthase (FASN) SHP1 Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W040256

*Acid phosphatase, wheat* ACP	Endogenous Metabolite	Metabolic Disease Cancer
Acid phosphatase, wheat (ACP) is an enzyme that removes phosphate from other molecules during digestion. Acid phosphatase catalyzes the conversion of orthophosphoric monoester and H2O to alcohol and phosphoric acid .

HY-D1491A

Fast Red Violet LB Zinc chloride	Fluorescent Dye	Others
Fast Red Violet LB Zinc chloride is a stain that stains tartrate-resistant acid phosphatase (TRAP) and Fast Red Violet LB Zinc chloride can be used to stain alkaline phosphatase (ALP) activity .

HY-E70360

*Acid Phosphatase* (ACP), Sweet Potato** Non-prostatic acid phosphatase, ACP, Orthophosphoric-monoester phosphohydrolase acid optimum, acid phosphatase, AcPase, Apase	Others	Others
Acid Phosphatase (ACP), Sweet Potato (Non-prostatic acid phosphatase, ACP, Orthophosphoric-monoester phosphohydrolase acid optimum, Acid Phosphatase, AcPase, Apase) is a biological material or organic compound that can be used in life science research .

HY-E70358

*Acid Phosphatase, Prostatic (ACP/PAP)* ACP, PAP, acid Phos, 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, Thiamine monophosphatase, TMPase, PAPf39	Others	Others
Acid Phosphatase, Prostatic (ACP/PAP) (Acid Phos, 5'-nucleotidase, Thiamine monophosphatase, PAPf39) is a biological material or organic compound that can be used in life science research .

HY-E70382

Shrimp Alkaline Phosphatase	Phosphatase Biochemical Assay Reagents	Others
Shrimp Alkaline Phosphatase (SAP), a nucleotide phosphatase, can catalyze the removal of 5′ phosphates from nucleic acid templates. Shrimp Alkaline Phosphatase is readily inactivated in the absence of chelators and is widely used phosphatases in molecular cloning .

HY-D1676

Thymolphthalein monophosphate disodium hydrate	Phosphatase	Others
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .

HY-D1491

Fast Red Violet LB	Fluorescent Dye	Others
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining .

HY-E70373

λ Protein phosphatase	Biochemical Assay Reagents	Others
λ Protein phosphatase is a serine/threonine phosphatase encoded by bacteriophage Lambda. λ Protein phosphatase is activated with requirement for divalent cations, such as Mn ²⁺. λ Protein phosphatase is able to dephosphorylate casein, adenovirus E1A protein, and the α subunit of phosphorylase kinase

HY-149492

Phosphatase-IN-1	Phosphatase Fungal	Infection
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a *phosphatidate phosphatase* (Pah)** inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads .

HY-156970

Phosphatase Binder-1	Phosphatase	Cancer
Phosphatase Binder-1 (comppund i-196) provides bifunctional compounds that efficiently dephosphorylate certain phospho-activated target proteins. Phosphatase Binder-1 plays an important role in cancer .

HY-P2818E

*Alkaline Phosphatase, Calf intestinal* 1 Publications Verification Apase, Calf intestinal	Endogenous Metabolite Phosphatase	Inflammation/Immunology
Alkaline Phosphatase (Apase), Calf intestinal is an alkaline phosphatase from Calf intestinal, and is one of the most active alkaline phosphatases. Alkaline Phosphatase catalyzes the removal of phosphate group from various compounds that are phosphorylated. Intestinal Alkaline Phosphatase regulates intestinal surface pH, absorption of lipids, detoxification of free nucleotides and bacterial lipopolysaccharide, attenuation of intestinal inflammation. Alkaline Phosphatase with different origin may have differences in optimum pH values for hydrolysis of different substrates .

HY-P2818

*Alkaline phosphatase, Bovine intestine* 1 Publications Verification Apase	Endogenous Metabolite Glutathione Peroxidase Bacterial	Infection Inflammation/Immunology
Alkaline phosphatase, Bovine intestine (Apase) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Bovine intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Bovine intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Bovine intestine improves TNBS-induced colon inflammation .

HY-P2818C

*Alkaline phosphatase, microorganism* 1 Publications Verification Apase, microorganism	Endogenous Metabolite	Metabolic Disease
Alkaline phosphatase, microorganism is a membrane-bound glycoprotein. It can hydrolyze monophosphate esters at alkaline pH, releasing inorganic phosphate. Alkaline phosphatase, microorganism is also capable of dephosphorylating proteins, and the balance between protein phosphorylation and dephosphorylation plays a key role in regulating various cellular functions. Alkaline phosphatase, microorganism can regulate cell proliferation and differentiation .

HY-P2818A

*Alkaline phosphatase, Escherichia coli* Apase, Escherichia coli	Endogenous Metabolite	Others
Alkaline phosphatase, Bovine intestine (Apase) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Bovine intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Bovine intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Bovine intestine improves TNBS-induced colon inflammation .

HY-149942

PAP-IN-1	Phosphatase	Others
PAP-IN-1 (compound 28) is an inhibitor of purple acid phosphatases (PAPs), a ubiquitous binuclear metallohydrolase. PAP-IN-1 inhibits mammalian PAP with K_i value of 168 nM. PAP-IN-1 targets to pig PAP with K_ic value of 0.17 μM. PAP inhibitors can be used for research of anti-osteoporotic drugs .

HY-P2818B

*Alkaline phosphatase, Chicken Intestine* Apase, Chicken Intestine	Endogenous Metabolite	Metabolic Disease
Alkaline phosphatase, Chicken Intestine (Apase, Chicken Intestine) is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values .

HY-N2511

Trimyristin	Cholinesterase (ChE) Phosphatase Endogenous Metabolite	Metabolic Disease
Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC₅₀s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-E70359

*Alkaline Phosphatase* (ALP), Porcine Kidney** ALP, Orthophosphoric-Monoester Phosphohydrolase	Others	Others
Alkaline Phosphatase (ALP), Porcine Kidney (ALP, Orthophosphoric-Monoester Phosphohydrolase) is a biological material or organic compound that can be used in life science research .

HY-N2511R

Trimyristin (Standard)	Reference Standards Cholinesterase (ChE) Phosphatase Endogenous Metabolite	Metabolic Disease
Trimyristin (Standard) is the analytical standard of Trimyristin. This product is intended for research and analytical applications. Trimyristin, an active molluscicidal component of?Myristica fragrans?Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of?Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-P5363A

PAP 248-286 acetate Prostatic acid phosphatase (248-286) acetate	HIV	Infection
PAP 248-286 (Prostatic acid phosphatase (248-286)) acetate is a biological active peptide. PAP (248-286) acetate is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells. .

HY-P5363

PAP 248-286 Prostatic acid phosphatase (248-286)	HIV	Infection
PAP 248-286 (Prostatic acid phosphatase (248-286)) is a biological active peptide. PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells .

HY-175023

OncoACP3	Others	Cancer
OncoACP3 (Compound s43) is a high affinity radioligand for *prostatic acid phosphatase* (ACP3)**. OncoACP3, radiolabelled with lutetium-177, selectively accumulates in enzyme-expressing tumors and shows a potent anti-tumor activity with excellent tumor-selective payload deposition in HT1080.hACP3 and PC3.hACP3 tumor-bearing mice model. OncoACP3 can be used for prostate cancer research .

HY-D0852

Sodium orthovanadate 10+ Cited Publications	Phosphatase	Cancer
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-115759

N-Octylmaleimide	Phosphatase	Metabolic Disease
N-Octylmaleimide is an alkylmaleimide, which can inhibit rat liver glucose 6-phosphatase .

HY-W554649

p-Aminophenyl phosphate	Phosphatase	Others
p-Aminophenyl phosphate is an alkaline phosphatase substrate, and can be used for the electrochemical measurement of alkaline phosphatase activity .

HY-131549A

bpV(bipy) hydrate	PTEN Phosphatase	Others
bpV(bipy) hydrate is the inhibitor for phosphoinositide 3-phosphatase (PTEN) and protein tyrosine phosphatases (PTP-β and PTP-1B) with IC₅₀s of 18, 60.3, and 164 nM, respectively .

HY-160973

ELF97 phosphate ELFP	Biochemical Assay Reagents	Others
ELF97 phosphate (ELFP) is a phosphatase substrate, which can produced a fluorescent, water-insoluble product ELF97 alcohol after hydrolysis by phosphatases. ELF97 phosphate can be utilized to study and quantify the activity of extracellular phosphatases of algae in natural water .

HY-170462

CSPD substrate	Biochemical Assay Reagents	Others
CSPD substrate is a chemiluminescent substrate of alkaline phosphatase. CSPD substrate provides the enhanced alkaline phosphatase sensitivity and a more simplified assay .

HY-137942

1-Naphthyl phosphate disodium salt, 98% α-Naphthyl phosphate disodium salt, 98%	Biochemical Assay Reagents	Others
1-Naphthyl phosphate disodium salt, 98% is a histochemical substrate for acidic and alkaline phosphatases, and can also be used as a substrate for measuring prostatic acid phosphatase.

HY-116022B

4-Nitrophenyl phosphate ditromethamine p-Nitrophenyl phosphate ditromethamine	Biochemical Assay Reagents	Others
4-Nitrophenyl phosphate ditromethamine is an enzyme substrate commonly used in biochemical assays to measure the activity of various phosphatases, including alkaline phosphatase. 4-Nitrophenylphosphate has unique chemical properties that allow it to be hydrolyzed by phosphatases, releasing a yellow product that can be detected spectrophotometrically.

HY-138821

BCIP potassium	Biochemical Assay Reagents	Others
BCIP (potassium) is a chromogenic substrate commonly used to detect the enzymatic activity of alkaline phosphatase. When dephosphorylated by alkaline phosphatase, BCIP produces a blue precipitate.

HY-16443

S-4048	Phosphatase	Metabolic Disease
S-4048 is a Glucose-6-phosphatase (G6Pase) inhibitor with an IC₅₀ value of 9.4 nM for rat microsomes.

HY-N12613

Sydowimide A	SHP1 Phosphatase	Inflammation/Immunology
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

HY-131475A

Naphthol AS-BI phosphate disodium hydrate	Biochemical Assay Reagents	Others
Naphthol AS-BI phosphate (disodium hydrate) is used as a substrate for determining the activity of both alkaline and acidic phosphatases; it can also be used to measure the activity of individual cell acid phosphatase.

HY-112832

Lumigen APS-5	Phosphatase	Infection
Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

HY-N3267

Methyl pseudolarate B	Phosphatase	Metabolic Disease
Methyl pseudolarate B, a natural diterpenoid, is a *protein tyrosine phosphatase* 1B (PTP1B)** (Phosphatase) inhibitor with an IC₅₀ value of 10.9 μM .

HY-148001

EWP 815	Phosphatase Dopamine β-hydroxylase	Others
EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P₂ phosphatase and Ins(1,4,5)P₃ 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity .

HY-N14462

Pluraflavin A	Antibiotic Bacterial	Infection Cancer
Pluraflavin A is an antitumor antibiotic. Pluraflavin A has the effect of inhibiting the transcription of glucose-6-phosphatase gene and has good anti-proliferation activity on tumor cells .

HY-19776

3α-Aminocholestane 5 Publications Verification	Phosphatase	Cancer
3α-Aminocholestane is a selective *SH2 domain-containing inositol-5′-phosphatase* 1 (SHIP1) inhibitor with an IC₅₀** of ~2.5 μM.

HY-124644

1E7-03	HIV Phosphatase	Infection
1E7-03, a low MW tetrahydroquinoline derivative targeting protein phosphatase-1, can inhibit HIV-1 transcription .

HY-N4185

Licoflavone A 2 Publications Verification	Phosphatase	Neurological Disease
Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC₅₀ of 54.5 μM .

HY-128153

Thienopyridone 1 Publications Verification	Phosphatase Apoptosis	Cancer
Thienopyridone is a potent and selective **phosphatase of regenerating liver (PRL) phosphatase inhibitor with IC₅₀s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3*, respectively. Thienopyridone shows minimal effects on other phosphatases. Thienopyridone induces p130Cas cleavage and apoptosis* and has anticancer effects .

HY-133146

DJ001	Phosphatase Apoptosis	Inflammation/Immunology
DJ001 is a highly specific, selective and non-competitive *protein tyrosine phosphatase-σ (PTPσ)* inhibitor with an IC₅₀ of 1.43 μM. DJ001 displays no inhibitory activity against other phosphatases, with only modest inhibitory activity against Protein Phosphatase 5. DJ001 promotes promote hematopoietic stem cell regeneration .

HY-131443

TRC-766	Phosphatase	Others
TRC-766 is a negative control of RTC-5 (TRC-382). TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase .

HY-18983

Calyculin A 15+ Cited Publications (-)-Calyculin A	Phosphatase	Cancer
Calyculin A ((-)-Calyculin A) is a potent and cell-permeable *protein phosphatase* 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC₅₀**s of 2 nM and 0.5-1 nM, respectively .

HY-W322022

Disodium phenyl phosphate	Biochemical Assay Reagents	Others
Disodium Phenyl phosphate is a substrate for alkaline phosphatase .

HY-P5447

RRLIEDAEpYAARG	Phosphatase	Others
RRLIEDAEpYAARG is a biological active peptide. (Phosphatase substrate.)

HY-N12776

Illudalic acid	Phosphatase	Cancer
Illudalic acid is a potent and selective Leukocyte antigen-related (LAR) phosphatase inhibitor with an IC₅₀ value of 1.30 µM. Illudalic acid inhibits LAR phosphatase through covalent ligation to the catalytic cysteine residue .

HY-155374

PP5-IN-1	Phosphatase Apoptosis	Cancer
PP5-IN-1 (Compound P053) is a competitive inhibitor of *Serine/threonine protein phosphatase-5 (PP5)* that binds to its catalytic domain and causes apoptosis in renal cancer .

HY-128978

(E,E)-RAMB4	Phosphatase	Metabolic Disease
(E,E)-RAMB4 is a potent and selective *potent protein tyrosine phosphatase-1B (PTP1B)* inhibitor extracted from patent CN103626692A, example 1 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W040256

*Acid phosphatase, wheat* ACP	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Acid phosphatase, wheat (ACP) is an enzyme that removes phosphate from other molecules during digestion. Acid phosphatase catalyzes the conversion of orthophosphoric monoester and H2O to alcohol and phosphoric acid .

HY-P2818

*Alkaline phosphatase, Bovine intestine* 1 Publications Verification Apase	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite Glutathione Peroxidase Bacterial
Alkaline phosphatase, Bovine intestine (Apase) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Bovine intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Bovine intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Bovine intestine improves TNBS-induced colon inflammation .

HY-N2511

Trimyristin	Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Myristicaceae Plants Myristica fragrans Houtt. Endogenous metabolite Disease Research Fields	Cholinesterase (ChE) Phosphatase Endogenous Metabolite
Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC₅₀s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-N4185

Licoflavone A 2 Publications Verification	Structural Classification Flavonoids Neurological Disease Classification of Application Fields Flavones Leguminosae Source classification Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Disease Research Fields	Phosphatase
Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC₅₀ of 54.5 μM .

HY-N2511R

Trimyristin (Standard)	Structural Classification Natural Products Microorganisms Source classification Myristicaceae Plants Myristica fragrans Houtt. Endogenous metabolite	Reference Standards Cholinesterase (ChE) Phosphatase Endogenous Metabolite
Trimyristin (Standard) is the analytical standard of Trimyristin. This product is intended for research and analytical applications. Trimyristin, an active molluscicidal component of?Myristica fragrans?Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of?Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-N12613

Sydowimide A	Structural Classification Natural Products Microorganisms Marine natural products Source classification Marine microorganism	SHP1 Phosphatase
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

HY-N3267

Methyl pseudolarate B	Structural Classification Pinaceae Terpenoids Source classification Diterpenoids Pseudolarix amabilis (J. Nelson) Rehder Plants	Phosphatase
Methyl pseudolarate B, a natural diterpenoid, is a *protein tyrosine phosphatase* 1B (PTP1B)** (Phosphatase) inhibitor with an IC₅₀ value of 10.9 μM .

HY-N14462

Pluraflavin A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Pluraflavin A is an antitumor antibiotic. Pluraflavin A has the effect of inhibiting the transcription of glucose-6-phosphatase gene and has good anti-proliferation activity on tumor cells .

HY-N12776

Illudalic acid	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Phosphatase
Illudalic acid is a potent and selective Leukocyte antigen-related (LAR) phosphatase inhibitor with an IC₅₀ value of 1.30 µM. Illudalic acid inhibits LAR phosphatase through covalent ligation to the catalytic cysteine residue .

HY-N10186

Dibefurin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Phosphatase Endogenous Metabolite
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

HY-P2040

Nodularin	Structural Classification other families Cyclopeptides Ketones, Aldehydes, Acids Marine natural products Source classification Plants	Phosphatase
Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .

HY-B0579

Cyclosporin A Maximum Cited Publications 139 Publications Verification Cyclosporine A; Ciclosporin A; CsA	Structural Classification Natural Products Microorganisms Classification of Application Fields Anti-aging Source classification Inflammation/Immunology Disease Research Fields Cancer	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of *protein phosphatase* 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18** adhesion .

HY-106702A

Fostriecin PD 110161; CL 1565A; CI-920	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Topoisomerase Phosphatase
Fostriecin is a triene antibiotic. Fostriecin is a topoisomerase II and *protein phosphatase* PP2A** inhibitor .

HY-W008385

H-HoArg-OH	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-B0579R

Cyclosporin A (Standard) Cyclosporine A (Standard); Ciclosporin A (Standard); CsA (Standard)	Structural Classification Natural Products Microorganisms Source classification	Molecular Glues Reference Standards Complement System Antibiotic Cyclophilin
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N15015

Dephostatin	Structural Classification Natural Products Microorganisms Source classification	Phosphatase
Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range .

HY-N2111

Momordicoside A	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Metabolic Disease Plants Disease Research Fields Momordica charantia Linn.	Phosphatase
Momordicoside A is isolated from Momordica charantia L. Momordicoside A has the inhibitory effect on *protein tyrosine phosphatase* (PTP1B)** .

HY-N10648

PTP1B-IN-20	Quinones Structural Classification Anthraquinones Rubiaceae Knoxia valerianoides Thorel ex Pitard Plants	Phosphatase
PTP1B-IN-20 is a selective inhibitor of *protein tyrosine phosphatase* 1B (PTP1B; IC₅₀*=1.05 μM) over the highly homologous T-cell protein tyrosine phosphatase* (TCPTP; IC₅₀=78.0 μM), which is a key target for type 2 diabetes inhibition .

HY-N8789

2-Hydroxymethyl-3-hydroxyanthraquinone	Quinones Anthraquinones Rubiaceae Plants Morinda officinalis How	Phosphatase
2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic *tartrate-resistant acid phosphatase* (TRAP)** activity .

HY-114336

Enocyanin 2 Publications Verification	Anthocyans Flavonoids Classification of Application Fields Source classification Vitis vinifera cv. Zalema Plants Vitaceae Disease Research Fields Inflammation/Immunology	Phosphatase
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity .

HY-N15220

Dipsacus saponin X	Structural Classification Polysaccharides Caprifoliaceae Source classification Dipsacus asper Wall. Plants Saccharides	Endogenous Metabolite Phosphatase
Dipsacus saponin X (compound 7) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .

HY-N2247

Guaiacin	Zingiber officinale Roscoe Structural Classification Classification of Application Fields Source classification Lignans Phenols Polyphenols Metabolic Disease Phenylpropanoids Plants Disease Research Fields Zingiberaceae	Phosphatase
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .

HY-N15231

Dipsacus saponin XII	Structural Classification Polysaccharides Caprifoliaceae Source classification Dipsacus asper Wall. Plants Saccharides	Endogenous Metabolite Phosphatase
Dipsacus saponin XII (compound 6) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .

HY-N12736

Dehydrodanshenol A	Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Source classification Diterpenoids Plants	Phosphatase
Dehydrodanshenol A is a non-competitive inhibitor of Protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ value of 8.5 μM. Dehydrodanshenol A can be used in diabetes-related research .

HY-N6650

Isotanshinone IIA	Quinones Classification of Application Fields Labiatae Source classification Samanea saman (Jacq.) Merr. Metabolic Disease Plants Naphthalene Quinones Disease Research Fields	Phosphatase
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC₅₀ 0f 11.4 μM.

HY-N4317

Ethoxysanguinarine 1 Publications Verification	Alkaloids Classification of Application Fields Source classification Quinoline Alkaloids Macleaya cordata (Willd.) R. Br. Plants Disease Research Fields Papaveraceae Cancer	Apoptosis
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of *protein phosphatase* 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis** and inhibits colorectal cancer cells growth .

HY-N15308

Kanjone	Structural Classification Natural Products Millettia peguensis Ali Leguminosae Source classification Plants	Phosphatase
Kanjone is a compound found in Millettia peguensis and can be used for the synthesis of protein tyrosine phosphatase 1B (PTP1B) inhibitors. Kanjone holds promise for research in the fields of diabetes and neurological disorders .

HY-N0374

Licochalcone C 3 Publications Verification	Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Source classification Metabolic Disease Plants Glycyrrhiza uralensis Fisch. Disease Research Fields	Glycosidase
Licochalcone C could inhibit α-glucosidase, with IC₅₀s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

HY-106702

Fostriecin sodium PD 110161 sodium; CL 1565A sodium; CI-920 sodium	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Phosphatase
Fostriecin (sodium) (compound 1, CI-920) is an antibiotic with a cytotoxic activity. Fostriecin (sodium) is also an inhibitor of protein phosphatase including PP4 (IC₅₀= 3 nM)and PP2 (IC₅₀=1.5 nM) .

HY-100786

DL-AP3	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite mGluR Phosphatase
DL-AP3 is a competitive mGluR1 and mGluR5 antagonist. DL-AP3 is also an inhibitor of phosphoserine phosphatase. DL-AP3 has neuroprotective effect .

HY-13756A

Tacrolimus monohydrate 85+ Cited Publications FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Inflammation/Immunology Disease Research Fields	Phosphatase FKBP Autophagy Bacterial Antibiotic
Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

HY-N1549

Prunin 1 Publications Verification Naringenin 7-0-glucoside	Structural Classification Flavonoids other families Classification of Application Fields Flavonones Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	Enterovirus Phosphatase
Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC₅₀ of 5.5 μM .

HY-N10064

Ficusonolide	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Others
Ficusonolide has significant antidiabetic activity with a possible mechanism of interaction with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.

HY-N4143

Cyanidin 3-arabinoside	other families Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	Phosphatase
Cyanidin 3-arabinoside is a selective and reversible *protein tyrosine phosphatase* 1B (PTP1B) inhibitor, with an IC₅₀** of 8.91 μM. Cyanidin 3-arabinoside is potential for the research of type 2 diabetes .

HY-119539

Limocitrin	Structural Classification Flavonols Flavonoids Source classification Plants Platanaceae Platanus orientalis L.	Phosphatase
Limocitrin is a natural product that can be isolated from the buds of P. acerifolia and P. orientalis. Limocitrin suppresses estradiol-dependent proliferation of MCF7 cells weakly but estradiol-induced AlkP (alkaline phosphatase) expression only marginally .

HY-13756

Tacrolimus 85+ Cited Publications FK506; Fujimycin; FR900506	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Macrolide Antibiotics Animals Classification of Application Fields Antibiotics Source classification Disease Research Inflammation/Immunology Disease Research Fields	Phosphatase FKBP Bacterial Autophagy Antibiotic
Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

HY-N2451

Aloe-emodin-8-O-β-D-glucopyranoside 1 Publications Verification	Quinones Structural Classification Monophenols Liliaceae Classification of Application Fields Anthraquinones Source classification Phenols Aloe vera (L.) Burm. f. Metabolic Disease Plants Disease Research Fields	Phosphatase
Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of *human protein tyrosine phosphatase* 1B (hPTP1B) with an IC₅₀** of 26.6 μM .

HY-W661499

Orellanine	Structural Classification Natural Products Microorganisms Source classification	Phosphatase
Orellanine is a fungal nephrotoxin. Orellanine is also a competitive inhibitor of alkaline phosphatase. Orellanine induces cell death in proximal tubular cells and in ccRCC cells. Orellanine can be used for research of clear cell renal cell carcinoma (ccRCC) .

HY-N8366

Alloisoimperatorin	Structural Classification Source classification Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt.	Phosphatase
Alloisoimperatorin (Compound 5) is a phytoestrogen that can be isolated from Angelica dahurica. Alloisoimperatorin can induce alkaline phosphatase (AP) activity with an EC₅₀ of 0.8 μg/mL. Alloisoimperatorin can be used in the study of hormone-dependent cancers and the alleviation of menopausal symptoms .

HY-N1230

Sophoraisoflavone A Allolicoisoflavone B	Structural Classification Flavonoids Leguminosae Glycyrrhiza inflata Batal. Source classification Plants Isoflavones	Phosphatase
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent *protein tyrosine phosphatase* 1B (PTP1B) inhibitor with an IC₅₀** value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation .

HY-N12108

Forphenicine	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols	Phosphatase
Forphenicine is a bacterial metabolite that is found in S. fulvoviridis and an inhibitor of alkaline phosphatase. Forphenicine inhibits the growth of HL-60 leukemia cells at 10 µM. Forphenicine also increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE) .

HY-N8200

Cassiaside B2	Structural Classification Monophenols Classification of Application Fields Source classification Phenols Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Inflammation/Immunology Disease Research Fields	Phosphatase Monoamine Oxidase 5-HT Receptor
Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist . ..

HY-N7599

Chrysophanol triglucoside	Quinones Monophenols Classification of Application Fields Anthraquinones Source classification Phenols Metabolic Disease Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Disease Research Fields	Phosphatase Glycosidase
Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits *protein tyrosine phosphatases* 1B (PTP1B) and α-glucosidase with IC₅₀**s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research .

HY-N10378

Rubrofusarin 6-O-β-D-glucopyranoside	Monophenols Classification of Application Fields Neurological Disease Source classification Phenols Metabolic Disease Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Disease Research Fields	Phosphatase
Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC₅₀ of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression .

HY-N11441

cis-Ferulic acid 4-O-β-D-glucopyranoside	Structural Classification Ketones, Aldehydes, Acids Zygophyllaceae Source classification Plants Nitraria sibirica Pall	Phosphatase
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B .

HY-113143A

Galactose 1-phosphate Potassium salt	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
Galactose 1-phosphate Potassium salt is an intermediate in the galactose metabolism and nucleotide sugars. Galactose 1-phosphate Potassium salt is an inhibitor of a series of enzymatic activities such as phosphoglucomutase, glucose-6-phos phate phosphatase, glucose-6-phosphate dehydrogenase, glycogen phosphorylase, UDP-glucose pyrophosphorylase and inositol monophosphatase .

HY-163899

(+)-Crinatusin A1	Structural Classification Other Monoterpenes Terpenoids Source classification Myrtaceae Plants Syzygium nervosum Candolle	Phosphatase
(+)-Crinatusin A1 (Compound (+)- 4) is a chalcone-monoterpene hybrid, which can be isolated from Cleistocalyx operculatus. (+)-Crinatusin A1 is an inhibitor for *protein tyrosine phosphatase* 1B (PTP1B) with IC₅₀** of 0.9 μM. (+)-Crinatusin A1 exhibits potential as an antidiabetic agent .

HY-13756R

Tacrolimus (Standard) FK506 (Standard); Fujimycin (Standard); FR900506 (Standard)	Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Macrolide Antibiotics Animals Antibiotics Source classification Disease Research	Reference Standards Phosphatase FKBP Bacterial Autophagy Antibiotic
Tacrolimus (Standard) is the analytical standard of Tacrolimus. This product is intended for research and analytical applications. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

HY-N6663

3-Carene	Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	COX
3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

HY-N12761

Penpaxilloids A	Structural Classification Terpenoids Marine natural products Source classification Diterpenoids Marine microorganism	Phosphatase Glycosidase
Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity .

Cat. No.	Product Name	Chemical Structure

HY-B0537AS

Pentamidine-d4 dihydrochloride

Pentamidine-d₄ (dihydrochloride) is the deuterium labeled Pentamidine dihydrochloride. Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC₅₀ of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities .

HY-B0579S3

Cyclosporin A-13C2,d4
Cyclosporin A- ¹³C₂,d₄ (Cyclosporine A- ¹³C₂,d₄; Ciclosporin A- ¹³C₂,d₄) is a ¹³C labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of *protein phosphatase* 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18** adhesion .

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-13756S

Tacrolimus-13C,d2
Tacrolimus- ¹³C,d₂ is a ¹³C-labeled and deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

HY-B0579S5

Cyclosporin A-d12
Cyclosporin A-d₁₂ (Cyclosporine A-d₁₂) is deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of *protein phosphatase* 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18** adhesion .

HY-B0579S2

Cyclosporin A acetate-d4
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of *protein phosphatase* 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18** adhesion .

HY-W008385S

H-HoArg-OH-d4
H-HoArg-OH-d₄ is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-B2006S

Fenvalerate-d5
Fenvalerate-d₅ is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC₅₀ of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .

HY-N2511S

Trimyristin--d15
Trimyristin--d₁₅ is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC₅₀s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively .

HY-13756S2

Tacrolimus-d3
Tacrolimus-d₃ (FK506-d₃) is deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

HY-106827S1

Trimegestone-13C,d3

Trimegestone- ¹³C,d₃ is ¹³C and deuterated labeled Trimegestone (HY-106827). Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. Trimegestone binds to progesterone receptor (PR) with an IC₅₀ value of 3.3 nM (rat PR). Trimegestone increases alkaline phosphatase activity (EC₅₀=0.1 nM) but not luciferase activity. Trimegestone also shows a weak antiandrogenic activity (weak androgen receptor affinity). Trimegestone can be used in studies of contraception or menopausal syndromes .

HY-78726S

Fosamprenavir-d4

Fosamprenavir-d₄ is the Deuterium-labeled Fosamprenavir (HY-78726). Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection .

HY-78726S2

Fosamprenavir-13C6

Fosamprenavir- ¹³C₆ is the ¹³C-labeled Fosamprenavir (HY-78726). Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection .

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