(4-Phenylphenoxy)phosphonic acid

Cat. No.: HY-171615 Purity: 99.70%: Data Sheet
SDS

COA
Handling Instructions
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(4-Phenylphenoxy) phosphonic acid is a protein tyrosine phosphatase (PTP) inhibitor (K_M: 86 μM). (4-Phenylphenoxy) phosphonic acid can be used in tuberculosis research.

For research use only. We do not sell to patients.

(4-Phenylphenoxy)phosphonic acid Chemical Structure

CAS No. : 46817-52-1

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Purity & Documentation
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Description

(4-Phenylphenoxy) phosphonic acid is a protein tyrosine phosphatase (PTP) inhibitor (K_M: 86 μM). (4-Phenylphenoxy) phosphonic acid can be used in tuberculosis research^[1].

Molecular Weight

250.19

Formula

C₁₂H₁₁O₄P

CAS No.

46817-52-1

Appearance

Solid

Color

Light yellow to khaki

SMILES

O=P(O)(OC1=CC=C(C2=CC=CC=C2)C=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (499.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9970 mL	19.9848 mL	39.9696 mL
5 mM	0.7994 mL	3.9970 mL	7.9939 mL
10 mM	0.3997 mL	1.9985 mL	3.9970 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.70%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (248 KB) HNMR (253 KB) CNMR (236 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Soellner MB, et al. Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB. J Am Chem Soc. 2007 Aug 8;129(31):9613-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.9970 mL	19.9848 mL	39.9696 mL	99.9241 mL
	5 mM	0.7994 mL	3.9970 mL	7.9939 mL	19.9848 mL
	10 mM	0.3997 mL	1.9985 mL	3.9970 mL	9.9924 mL
	15 mM	0.2665 mL	1.3323 mL	2.6646 mL	6.6616 mL
	20 mM	0.1998 mL	0.9992 mL	1.9985 mL	4.9962 mL
	25 mM	0.1599 mL	0.7994 mL	1.5988 mL	3.9970 mL
	30 mM	0.1332 mL	0.6662 mL	1.3323 mL	3.3308 mL
	40 mM	0.0999 mL	0.4996 mL	0.9992 mL	2.4981 mL
	50 mM	0.0799 mL	0.3997 mL	0.7994 mL	1.9985 mL
	60 mM	0.0666 mL	0.3331 mL	0.6662 mL	1.6654 mL
	80 mM	0.0500 mL	0.2498 mL	0.4996 mL	1.2491 mL
	100 mM	0.0400 mL	0.1998 mL	0.3997 mL	0.9992 mL