2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Parasite Phosphatase
  4. Questin

Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays antiprotozoal activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer.

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Questin

Questin Chemical Structure

CAS No. : 3774-64-9

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Based on 1 publication(s) in Google Scholar

Questin Related Antibodies

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Description

Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays antiprotozoal activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer[1][2][3][4][5].

In Vitro

Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL, respectively[1].
Questin (48 h) strongly inhibits the growth of human colon cancer cells (SW620), with a GI50 value of 0.9 mg/mL[2].
Questin (50-100 μM; 24 h) shows certain toxicity to the human A549 lung cell line and reduces cell viability[3].
Questin displays a moderate level of selective antiprotozoal activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Questin Related Antibodies
Molecular Weight

284.26

Formula

C16H12O5
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C1C2=C(C=C(O)C=C2OC)C(C3=CC(C)=CC(O)=C13)=O
Structure Classification
Initial Source

marine-derived Aspergillus flavipes?HN4-13
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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Questin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Questin3774-64-9BacterialParasitePhosphataseSW620A549V. anguillarumV. harveyiantibacterialTritrichomonas foetusanticancerantiprotozoalInhibitorinhibitorinhibit

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