2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. Efzimfotase alfa

Efzimfotase alfa  (Synonyms: ALXN-1850)

Cat. No.: HY-P991210
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Efzimfotase alfa is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP).

For research use only. We do not sell to patients.

Efzimfotase alfa Chemical Structure

Efzimfotase alfa Chemical Structure

CAS No. : 2746354-58-3

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Description

Efzimfotase alfa is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP)[1][2].

Isotype

Fusion-[Homo sapiens ALPL (alkaline phosphatase, TNSALP, tissue non-specific alkaline phosphatase) 18-502]2-IGHG4 Fc (Fragment constant)-deca-aspartate
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SMILES

[Efzimfotase alfa]
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Efzimfotase alfa Related Classifications

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Keywords:

Efzimfotase alfa2746354-58-3ALXN-1850ALXN1850ALXN 1850PhosphataseTNSALPPpiPLPHPPInhibitorinhibitorinhibit

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