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R/S

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Click Chemistry:	PROTAC Synthesis (1) Azide (27) Alkynes (7)
Oligonucleotides:	Adenosine (2) Nucleoside Phosphoramidites (1) Nucleoside Analogs (8) Adenine (1) Human Pre-designed siRNA Sets (3) Antisense Oligonucleotides (2) Cytidine (1) siRNAs (3)

1254

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

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Inhibitory Antibodies

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Isotope-Labeled Compounds

Antibodies

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145728B

(R/S)-Alicaforsen (R/S)-ISIS-2302	Integrin	Inflammation/Immunology
(R/S)-Alicaforsen is the racemate of Alicaforsen composed of R and S configurations. Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.

HY-16106A

(8R,9S)-Talazoparib (8R,9S)-BMN-673; (8R,9S)-LT-673	PARP	Cancer
(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC₅₀ of 144 nM .

HY-14881C

(1S,2R)-Bedaquiline (1S,2R)-TMC207; (1S,2R)-R207910	Drug Intermediate	Others
(1S,2R)-Bedaquiline ((1S,2R)-TMC207) is a drug intermediate for synthesis of various active compounds.

HY-W681822

(R,S,S)-Dihydrotetrabenazine R,S,S-DHTBZ	Drug Metabolite Monoamine Transporter	Neurological Disease
(R,S,S)-Dihydrotetrabenazine (R,S,S-DHTBZ) is a kind of discrete isomeric secondary alcohol metabolites of Tetrabenazine (TBZ, HY-B0590), is a poor VMAT2 inhibitor (K_i = 690 nM) .

HY-112078A

(S,R,S,R)-AHPC-Me	Ligands for E3 Ligase	Cancer
(S,R,S,R)-AHPC-Me serves as a VHL ligand that facilitates the recruitment of the VHL protein.

HY-108501

(1R,1'S,3'R/1R,1'R,3'S)-L-054,264	Somatostatin Receptor	Neurological Disease
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective non-peptide human somatostatin receptor subtype 2 (sst₂) agonist. (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 can be used in the study of retinal neuromodulation .

HY-13623C

(1R,3S,4R)-ent-Entecavir (1R,3S,4R)-ent-BMS200475; (1R,3S,4R)-ent-SQ34676	HBV	Others
(1R,3S,4R)-ent-Entecavir ((1R,3S,4R)-ent-BMS200475; (1R,3S,4R)-ent-SQ34676) can be used to synthesize PROTAC targets to degrade deoxyribonucleic acid (DNA) polymerase .

HY-172298

(R,S,S,S)-Orlistat (R,S,S,S)-Tetrahydrolipstatin; (R,S,S,S)-Ro-18-0647	Fatty Acid Synthase (FASN)	Infection
(R,S,S,S)-Orlistat is a stereogenic derivative of orlistat (tetrahydrolipstatin; THL) (HY-B0218). (R,S,S,S)-Orlistat inhibits three Mycobacterium tuberculosis lipid esterases, Ag85C (KI: 16.43 μM), Rv3802 (EC50: 16.2 nM), and Pks13-TE .

HY-158207S

(+)-Nebivolol-d4 (S,R,R,R)-Nebivolol-d₄; (S,R,R,R)-R 065824-d₄	Isotope-Labeled Compounds	Others
(S,R,R,R)-Nebivolol-d₄ is deuterium labeled (S,R,R,R)-Nebivolol .

HY-113519

14R(15S)-EET 14R(15S)-EpETrE; 14R(15S)-Epoxyeicosatrienoic acid	Drug Metabolite	Metabolic Disease
14R(15S)-EET (14R(15S)-EpETrE) is an oxylipin and a metabolite of Arachidonic acid (HY-109590) .

HY-B0395E

(1S,2R,7S)-Sitafloxacin (1S,2R,7S)-DU-6859a; DU-6856	Antibiotic Bacterial Topoisomerase	Infection
(1S,2R,7S)-Sitafloxacin (DU-6856) is an enantiomer of Sitafloxacin (HY-B0395). (1S,2R,7S)-Sitafloxacin is a topoisomerase inhibitor. (1S,2R,7S)-Sitafloxacin is an antibiotic. (1S,2R,7S)-Sitafloxacin has inhibitory activity against Escherichia coli DNA gyrase (IC50 0.18 μg/mL) and Staphylococcus aureus topoisomerase IV. (1S,2R,7S)-Sitafloxacin has antibacterial activity and can be used in the study of various bacterial infections .

HY-B1175

(2S,5R,6R)-Ticarcillin disodium	Antibiotic Bacterial	Infection
(2S,5R,6R)-Ticarcillin disodium is a semisynthetic antibiotic with bactericidal activities. (2S,5R,6R)-Ticarcillin disodium is the (2S,5R,6R)-enantiomer of Ticarcillin (HY-139805) .

HY-CE00186

(2S,6R,10R)-Trimethyl-hendecanoyl-CoA (2S,6R,10R)-Trimethyl-hendecanoyl-coenzyme A	Biochemical Assay Reagents	Others
(2S,6R,10R)-Trimethyl-hendecanoyl-CoA ((2S,6R,10R)-Trimethyl-hendecanoyl-coenzyme A) is a fatty acyl-CoA.

HY-N12486A

(3S,8R,9R)-Isofalcarintriol	Others	Neurological Disease Metabolic Disease Cancer
(3S,8R,9R)-Isofalcarintriol is a natural polyacetylene compound found in carrot root parts. (3S,8R,9R)-Isofalcarintriol is a potent longevity promoter that improves glucose metabolism and has anti-tumor activity. (3S,8R,9R)-Isofalcarintriol can affect cellular respiration, interact with the α subunit of mitochondrial ATP synthase, and promote mitochondrial biogenesis. (3S,8R,9R)-Isofalcarintriol can be used in the study of neurodegenerative diseases, metabolic diseases, and aging .

HY-W010271

(2S,3R,4S)-4-Hydroxyisoleucine (2S,3R,4S)-4-Hydroxy-L-isoleucine	Insulin Receptor	Metabolic Disease
(2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity .

HY-17447B

(1S,2R)-Tranylcypromine hydrochloride (1S,2R)-SKF 385 hydrochloride	Monoamine Oxidase Histone Demethylase	Neurological Disease
(1S,2R)-Tranylcypromine ((1S,2R)-SKF 385) hydrochloride is a potent antidepressant agent. (1S,2R)-Tranylcypromine hydrochloride can inhibits MAO and LSD1 .

HY-B1175R

(2S,5R,6R)-Ticarcillin disodium (Standard)	Reference Standards Antibiotic Bacterial	Infection
(2S,5R,6R)-Ticarcillin disodium (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin disodium. This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is a semisynthetic antibiotic with bactericidal activities. (2S,5R,6R)-Ticarcillin disodium is the (2S,5R,6R)-enantiomer of Ticarcillin (HY-139805).

HY-170348

(S)-(S,R,S,R)-AHPC-Me-N3	Ligands for E3 Ligase	Cancer
(S)-(S,R,S,R)-AHPC-Me-N3 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-32 (HY-170343) and can be used in the synthesis of PROTACs .

HY-116463B

(2S,3S)-E1R	Sigma Receptor	Neurological Disease
(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders .

HY-138678B

(S,R,R)-VH032	Ligands for E3 Ligase	Inflammation/Immunology
(S,R,R)-VH032 is a VHL ligand. (S,R,R)-VH032 can be used for synthesis of PROTAC NCOA4 degrader-1 (HY-163897) .

HY-109022A

(3R,5R,6S)-Atogepant (3R,5R,6S)-MK-8031; (3R,5R,6S)-AGN-241689	CGRP Receptor	Neurological Disease
(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of Atogepant (HY-109022). Atogepant is a calcitonin gene-related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.

HY-113040A

(17R,18S)-Epoxyeicosatetraenoic acid 17(R),18(S)-EETeTr	Calcium Channel	Cardiovascular Disease
(17R,18S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EETeTr) is a cytochrome P450 epoxygenase metabolite of eicosapentaenoic acid (HY-B0660). (17R,18S)-Epoxyeicosatetraenoic acid shows exerts negative chronotropic effects and protects neonatal rat cardiomyocytes against Ca ²⁺ overload. (17R,18S)-Epoxyeicosatetraenoic acid has the potential for the research of antiarrhythmic agent .

HY-CE01345

7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxyoctyl]cyclopentyl]heptanoyl-CoA 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxyoctyl]cyclopentyl]heptanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxyoctyl]cyclopentyl]heptanoyl-CoA (7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxyoctyl]cyclopentyl]heptanoyl-coenzyme A) is a coenzyme A derivative .

HY-18767A

(R,S)-Ivosidenib 1 Publications Verification (R,S)-AG-120	Isocitrate Dehydrogenase (IDH)	Cancer
(R,S)-Ivosidenib ((R,S)-AG-120) is a less active enantiomer of ivosidenib (AG-120). Ivosidenib can be used in the research of IDH1 mutant cancers .

HY-172514

(1R,2S,3R)-Aprepitant	Neurokinin Receptor	Cancer
(1R,2S,3R)-Aprepitant (Compound ent-4) is a competitive human neurokinin-1 (NK-1) receptor antagonist. (1R,2S,3R)-Aprepitant is promising for research of cancers and postoperative nausea and vomiting .

HY-W067425

2-(4-Hydroxyphenyl)propionic acid	Endogenous Metabolite	Metabolic Disease
2-(4-Hydroxyphenyl)propionic acid (Compound 1) is an aromatic carboxylic acid, which can be converted into its R and S glucosyl esters and glucosides by root culture of P. ginseng (Pg-1) .

HY-78931E

(R,S,R,S,R)-Boc-Dap-NE	Drug Intermediate	Cancer
(R,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-132593

Rovanersen WVE-120101	Huntingtin	Neurological Disease
Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen can be used for huntington’s disease research .

HY-W422400

Fluoroglutamine (2S,4R)	Biochemical Assay Reagents	Others Cancer
Fluoroglutamine (2S,4R) is a fluorinated derivative of glutamine. As a substrate for various aminotransferases, Fluoroglutamine (2S,4R) can be used as a tracer for positron emission tomography (PET) imaging. Fluoroglutamine (2S,4R) is applied in the research fields of tumor metabolism and imaging .

HY-163953

(S,R,S)-AHPC-Ala	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC-Ala is a ligand for E3 ubiquitinase. (S,R,S)-AHPC-Ala can be used to synthesize PROTAC SMARCA2/4-degrader-23 (HY-163876) .

HY-163951

(S,R,S)-AHPC-Ac	Ligands for E3 Ligase	Cancer
(S,R,S)-AHPC-Ac is a ligand for E3 ubiquitinase. (S,R,S)-AHPC-Ac can be used to synthesize PROTAC SMARCA2/4-degrader-22 (HY-163875) .

HY-100741C

(R,R)-S63845	Bcl-2 Family Drug Isomer	Cancer
(R,R)-S63845 is the isomer of S63845 (HY-100741), and can be used as an experimental control. S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a K_d of 0.19 nM for human MCL1 .

HY-78931F

(R,S,S,S,R)-Boc-Dap-NE	Drug Intermediate	Cancer
(R,S,S,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-78931C

(S,S,R,S,R)-Boc-Dap-NE	Drug Intermediate	Cancer
(S,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-CE00910

2S,6R,10R,14-Tetramethylpentadecanoyl-CoA 2S-Pristanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2S,6R,10R,14-Tetramethylpentadecanoyl-CoA (2S-Pristanoyl-coenzyme A) is a coenzyme A derivative.

HY-163934

(S,R,S)-AHPC-phenylacetic acid	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-phenylacetic acid is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-phenylacetic acid can be used to synthesize PROTAC SMARCA2/4-degrader-15 (HY-163868) .

HY-100754B

(2R,5S)-Ritlecitinib (2R,5S)-PF-06651600	JAK	Inflammation/Immunology
(2R,5S)-Ritlecitinib (2R,5S)-PF-06651600) is a JAK3 inhibitor (IC50=144.8 nM) .

HY-CE00259

(R)-S-(2-Tetradecyloxiranecarboxylate)-CoA (R)-S-(2-Tetradecyloxiranecarboxylate)-Coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(R)-S-(2-Tetradecyloxiranecarboxylate)-CoA ((R)-S-(2-Tetradecyloxiranecarboxylate)-Coenzyme A) is a coenzyme A derivative.

HY-167712

(2R,3S)-Azelaprag (2R,3S)-AMG 986	Drug Isomer Apelin Receptor (APJ)	Cardiovascular Disease Metabolic Disease
(2R,3S)-Azelaprag ((2R,3S)-AMG 986) (Example 238.0) is a precursor of an apelin receptor agonist (EC₅₀=12 nM) and an isomer of Azelaprag (HY-109111) .

HY-78931A

(R,S,S,R,S)-Boc-Dap-NE	Drug Intermediate	Cancer
(R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-110061

(2R,4R,6S)-Tubacin	HDAC Virus Protease Beta-lactamase	Infection
(2R,4R,6S)-Tubacin is the 2R,4R,6S enantiomer of Tubacin (HY-13428). Tubacin is a potent and selective inhibitor of HDAC6, with an IC₅₀ value of 4 nM and approximately 350-fold selectivity over HDAC1. Tubacin also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) .

HY-130138B

(5S,6R)-DiHETEs (5S,6R)-(11E)-DiHETE	Leukotriene Receptor	Inflammation/Immunology
(5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE (HY-130138A). (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC₅₀ of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists .

HY-157690A

19(R),20(S)-EDP	Drug Metabolite	Others
19(R),20(S)-EDP (compound 19(S),20(R)-2a) is an oxylipin and a metabolite of docosahexaenoic acid (HY-B2167) .

HY-118828A

(9S,13R)-12-Oxo phytodienoic acid (9S,13R)-12-OPDA	Lipoxygenase	Others
9S,13R)-12-Oxo phytodienoic acid is the isomerization of 12-oxo PDA (HY-118828). (9S,13R)-12-Oxo phytodienoic acid is a lipoxygenase metabolite in the leaves of green plants .

HY-155286

(7S,8R,17S)-RCTR1	Biochemical Assay Reagents	Infection Inflammation/Immunology
(7S,8R,17S)-RCTR1 is a specialized pro-resolving mediator, that exhibits anti-inflammatory and anti-infective activities. (7S,8R,17S)-RCTR1 promotes pathogen clearance, wound healing, tissue repair and regeneration .

HY-116463A

(2R,3S)-E1R	Sigma Receptor	Neurological Disease
(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders .

HY-N12962A

11R(12S)-EET	Others	Others
11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures .

HY-137390A

(3S,5R)-Fluvastatin potassium	HMG-CoA Reductase (HMGCR)	Cardiovascular Disease Metabolic Disease
(3S,5R)-Fluvastatin (potassium) is a synthetic hypolipidemic drug that inhibits HMG-CoA reductase activity. (3S,5R)-Fluvastatin (potassium) has similar antioxidative effects on copper ion-induced LDL oxidation compared to its 3R,5S enantiomer. (3S,5R)-Fluvastatin (potassium) and its metabolites demonstrate a potential to exhibit anti-atherosclerotic effects through their antioxidative activities. (3S,5R)-Fluvastatin (potassium) is clinically utilized as part of a racemic mixture for reducing plasma cholesterol levels.

HY-176157

12S(13R)-EpODE(γ) 12S(13R)-Epoxy-γ-octadecadienoic acid	Endogenous Metabolite	Metabolic Disease
12S(13R)-EpODE(γ) (12S(13R)-Epoxy-γ-octadecadienoic acid) is an epoxy-fatty acid .

HY-161194

(S,R,S)-AHPC-acetyl-azetidine-PIP-boc	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-acetyl-azetidine-PIP-boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. (S,R,S)-AHPC-acetyl-azetidine-PIP-boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010271

(2S,3R,4S)-4-Hydroxyisoleucine (2S,3R,4S)-4-Hydroxy-L-isoleucine	Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Trigonella foenum-graecum Linn. Disease Research Fields	Insulin Receptor
(2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound. (2S,3R,4S)-4-Hydroxyisoleucine can be isolated from Trigonella foenum-graecum. (2S,3R,4S)-4-Hydroxyisoleucine has anti-diabetic and anti-diabetic nephropathy activity .

HY-118828A

(9S,13R)-12-Oxo phytodienoic acid (9S,13R)-12-OPDA	Ketones, Aldehydes, Acids Source classification Solanum tuberosum L. Solanaceae Plants	Lipoxygenase
9S,13R)-12-Oxo phytodienoic acid is the isomerization of 12-oxo PDA (HY-118828). (9S,13R)-12-Oxo phytodienoic acid is a lipoxygenase metabolite in the leaves of green plants .

HY-N1976

(+)-(3R,8S)-Falcarindiol 1 Publications Verification (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol	Infection Natural Products Classification of Application Fields Source classification Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Umbelliferae Plants Inflammation/Immunology Disease Research Fields	Bacterial
(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC₅₀ of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra . Antineoplastic and anti-inflammatory activity . (+)-(3R,8S)-Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W021425

D-Mannosamine hydrochloride 1 Publications Verification (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Drug Derivative
D-Mannosamine ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors .

HY-N12486A

(3S,8R,9R)-Isofalcarintriol	Natural Products Source classification Umbelliferae Plants Mentha suaveolens Ehrh.	Others
(3S,8R,9R)-Isofalcarintriol is a natural polyacetylene compound found in carrot root parts. (3S,8R,9R)-Isofalcarintriol is a potent longevity promoter that improves glucose metabolism and has anti-tumor activity. (3S,8R,9R)-Isofalcarintriol can affect cellular respiration, interact with the α subunit of mitochondrial ATP synthase, and promote mitochondrial biogenesis. (3S,8R,9R)-Isofalcarintriol can be used in the study of neurodegenerative diseases, metabolic diseases, and aging .

HY-N12962A

11R(12S)-EET	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures .

HY-122938

Ceplignan (2S,3R)-Ceplignan	Araceae Source classification Acorus gramineus Soland. Phenols Plants	Others
Ceplignan ((2S,3R)-Ceplignan) is a neogenic lignan, which can be isolated from the rhizomes of Acorus tatarinowii Schott. (2S,3R)-Ceplignan and (2R,3S)-ceplignan are two isomers of Ceplignan .

HY-N12955

8(R),9(S)-EET	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
8(R),9(S)-EET is an isomer of Epoxyeicosatrienoic acid (HY-113489). 8(R),9(S)-EET processes its metabolism with cytosolic epoxide hydrolase (cEH), with a binding affinity of K_m of 41 μM .

HY-N2682

(7R,8S)-Dehydrodiconiferyl alcohol	Monophenols Leguminosae Source classification Phenols Gleditsia sinensis Lam. Plants	Others
(7R,8S)-Dehydrodiconiferyl alcohol is a natural product that can be isolated from the thorns of Gleditsia sinensis. (7R,8S)-Dehydrodiconiferyl alcohol shows antitumor activity .

HY-150092

8(S),9(R)-EET	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Drug Metabolite
8(S),9(R)-EET is an eicosanoid product of Arachidonic acid (AA; HY-109590) by cytochromes P450. 8(S),9(R)-EET dilates canine epicardial arterioles in a concentration-dependent manner with an EC₅₀ value of 121 nM .

HY-N6262

20(S),24(R)-Ocotillol	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields Araliaceae	Others
20(S),24(R)-Ocotillol is isolated from Panax ginseng .

HY-W040240R

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one (Standard)	Source classification Endogenous metabolite Saccharides	Reference Standards Endogenous Metabolite
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one (Standard) is the analytical standard of (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. This product is intended for research and analytical applications. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.

HY-N2207

rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan	Classification of Application Fields Source classification Lignans Other Diseases Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields	Others
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan is a chemical constituent of the fruit of Myristica fragrans.

HY-128732

rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Food Research	Endogenous Metabolite
rel-(2R,3S)-2,3-Dihydroxysuccinic acid (hydrate) is an endogenous metabolite.

HY-N12619

12R,13S-Dihydroxyfumitremorgin C	Alkaloids Microorganisms Other Alkaloids Source classification	LXR
12R,13S-Dihydroxyfumitremorgin C (compound 1) is a LXRα agonist .

HY-201672

18:1 BMP (S,R) ammonium	Lipid	Biochemical Assay Reagents
18:1 BMP (S,R) ammonium is a bis(monoacylglycero)phosphate (BMP) .

HY-125569

Leucomycin A5	Microorganisms Macrolide Antibiotics Antibiotics Source classification	Fungal Antibiotic
Leucomycin A5 has antifungal activity, with the MIC for Staphylococcus pyogenes pen S, Staphylococcus pyogenes pen R, and Staphylococcus faecalis being 0.8, 3.2, and 0.8 μg/mL, respectively .

HY-113025A

L-hydroxylysine dihydrochloride (2S,5R)-5-Hydroxylysine dihydrochloride	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues .

HY-N2380

N-Benzoyl-(2R,3S)-3-phenylisoserine	Alkaloids Classification of Application Fields Other Alkaloids Taxaceae Source classification Plants Disease Research Fields Taxus wallichiana Zucc. Cancer	Others
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol .

HY-W040240

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite generated by the thermal decomposition of β-D-glucopyranose and further isomerization .

HY-N12970

14S(15R)-EET	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .

HY-N15968

14:0 Hemi BMP (S,R) ammonium	Lipid	Biochemical Assay Reagents
14:0 Hemi BMP (S,R) ammonium is a bis(monoacylglycero)phosphate (BMP).

HY-N12962

11S(12R)-EET	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .

HY-N4045

Hierochin D (7S,8R)-Hierochin D	Source classification Lignans Scrophulariaceae Phenylpropanoids Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey	Others
Hierochin D ((7S,8R)-Hierochin D) is a product that can be isolated from .

HY-N3745

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol	Hedyotis uncinella Hook. et Arn. Source classification Lignans Rubiaceae Phenylpropanoids Plants	Others
(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol (compound 10) is a lignan isolated from Hedyotis uncinella .

HY-N9871

(6R,9S)-3-Oxo-α-ionol β-D-glucopyranoside	Terpenoids Sesquiterpenes Source classification Euphorbiaceae Plants Macaranga tanarius (L.) Muell. Arg.	Others
(6R,9S)-3-Oxo-α-ionol β-D-glucopyranoside is a natural product .

HY-N16375

(3R,6S)-Bassiatin	Natural Products Microorganisms Source classification	Drug Metabolite Fungal ATP Synthase
(3R,6S)-Bassiatin (Compound 5) is an enantiomer of the fungal metabolite Bassiatin (HY-165143). Bassianin is a compound isolated from fungi that has the activity of inhibiting erythrocyte membrane ATPase and causing cell lysis. Its inhibitory effect on ATPase may be due to membrane disruption .

HY-N8733

p-Menth-1-ene-3,6-diol (3R,4R,6S)-3,6-Dihydroxy-1-menthene	Natural Products Labiatae Source classification Erythrina poeppigiana Plants	Others
p-Menth-1-ene-3,6-diol ((3R,4R,6S)-3,6-Dihydroxy-1-menthene) is a Flavonoids product that can be isolated from the roots of Pueraria lobata .

HY-W011241

Cinchonine hydrochloride (8R,9S)-Cinchonine hydrochloride; LA40221 hydrochloride	Alkaloids other families Classification of Application Fields Source classification Quinoline Alkaloids Plants Disease Research Fields Cancer	Apoptosis Parasite
Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. Cinchonine hydrochloride activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells .

HY-111825A

(R)-1-PeCSO Isoalliin; trans-(+)-S-1-Propenyl-L-cysteine sulfoxide	Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Allium cepa L. Plants Disease Research Fields	Endogenous Metabolite
(R)-1-PeCSO (trans-(+)-S-1-Propenyl-L-cysteine sulfoxide) is the most abundant flavor precursor in onions .

HY-N12537A

(2R,3S)-PD-1/PD-L1-IN-38	Ketones, Aldehydes, Acids Labiatae Source classification Samanea saman (Jacq.) Merr. Plants	Aryl Hydrocarbon Receptor PD-1/PD-L1
(2R,3S)-PD-1/PD-L1-IN-38 (Compound (±)-13e) is an orally active Ah receptor (AhR) antagonist with in vivo and in vitro anticancer activity. (2R,3S)-PD-1/PD-L1-IN-38 promotes the secretion of INF-γ by CD8 ⁺T cells and inhibits the signal transduction of PD-1/PD-L1 .

HY-N1686

20S,24R-Epoxydammar-12,25-diol-3-one	Pinaceae Terpenoids Source classification Diterpenoids Pseudolarix amabilis (J. Nelson) Rehder Plants	Others
20S,24R-Epoxydammar-12,25-diol-3-one is a Triterpenoids product that can be isolated from the herbs of Pseudolarix kaempferi .

HY-N3859

Erythro-1-phenylpropane-1,2-diol (1R,2S)-1-Phenyl-1,2-propanediol	Natural Products Microorganisms Source classification	Others
Erythro-1-phenylpropane-1,2-diol? ((1R,2S)-1-Phenyl-1,2-propanediol) is a secondary alcohol .

HY-13716

Noscapine 2 Publications Verification (S,R)-Noscapine	Alkaloids Neurological Disease Classification of Application Fields Source classification Quinoline Alkaloids Papaver somniferum Linn. Plants Inflammation/Immunology Disease Research Fields Papaveraceae	Opioid Receptor Apoptosis
Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier .

HY-N13414

(3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol	Source classification Phenols Polyphenols Plants Curcuma longa Zingiberaceae	Others
(3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol is a natural product .

HY-N13541

(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol	Natural Products Source classification Cucurbitaceae Plants Momordica charantia Linn.	Others
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product .

HY-41094

cis-Isolimonenol (1S,4R)-p-Mentha-2,8-dien-1-ol	Other Monoterpenes Cymbopogon flexuosus Classification of Application Fields Terpenoids Gramineae Source classification Other Diseases Plants Disease Research Fields	Others
cis-Isolimonenol ((1S,4R)-p-Mentha-2,8-dien-1-ol) is the monoterpene alcohol that can be isolated from plants .

HY-N12784

(6S,9R)-2-Hydroxy-4-(2,6,6-trimethyl-4-oxo-cyclohex-2-enyl)-butyric acid	Ketones, Aldehydes, Acids Crassulaceae Source classification Sedum sarmentosum Bunge Plants	Others
(6S,9R)-2-Hydroxy-4-(2,6,6-trimethyl-4-oxo-cyclohex-2-enyl)-butyric acid is a hemiterpenoid and can be isolated from Sedum sarmentosum .

HY-N13510

(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol	Triterpenes Terpenoids Source classification Cucurbitaceae Plants Momordica charantia Linn.	Others
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a triterpenoid product that can be isolated from Momordica charantia .

HY-N8664

11(S),16(R)-Dihydroxyoctadeca-9Z,17-diene12,14-diyn-1-yl acetate	Natural Products Source classification Umbelliferae Plants Pluchea indica (L.) Less.	Others
11(S),16(R)-Dihydroxyoctadeca-9Z,17-diene12,14-diyn-1-yl acetate is a natural product .

HY-Y0152A

Cinchonine monohydrochloride hydrate (8R,9S)-Cinchonine monohydrochloride hydrate; LA40221 monohydrochloride hydrate	Cardiovascular Disease Infection Cinchona succirubra Pav. ex Klotzsch Alkaloids Classification of Application Fields Source classification Rubiaceae Metabolic Disease Quinoline Alkaloids Plants Disease Research Fields	Parasite Apoptosis
Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis .

HY-W750654

Adonixanthin (3S,3′R)-Adonixanthin	Natural Products Microorganisms Source classification	Akt ERK p38 MAPK MMP NADPH Oxidase Reactive Oxygen Species (ROS) Keap1-Nrf2
Adonixanthin ( (3S,3'R)-Adonixanthin), a carotenoid, is an orally active anti-oxidative and anti-carcinogenic agent. Adonixanthin shows an ability to suppress cell proliferation and migration in three types of glioblastoma cells Adonixanthin exerts cytoprotective effects against various types of damage and inhibits the increased production of ROS. Adonixanthin protects against light-induced cell damage through not only an anti-oxidative response but also through Nrf2 activation. Adonixanthin suppresses glioblastoma progression and adonixanthin improves blood-brain barrier hyper-permeability in an autologous blood ICH model. Adonixanthin can be used for the study of glioblastoma (GBM) and intracerebral hemorrhage (ICH) .

HY-13716R

Noscapine (Standard) (S,R)-Noscapine (Standard)	Alkaloids Source classification Quinoline Alkaloids Papaver somniferum Linn. Plants Papaveraceae	Reference Standards Opioid Receptor Apoptosis
Noscapine (Standard) is the analytical standard of Noscapine. This product is intended for research and analytical applications. Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier [4] .

HY-N10856

2H-1-Benzopyran-2-one, 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy-	Source classification Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt.	Others
6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source .

HY-N12870

(7S,8R)-4,9,9'-Trihydroxy-3,3',5-trimethoxy-8,4'-oxyneolignan 4-O-β-D-glucopyranoside	Smilacaceae Source classification Lignans Phenylpropanoids Plants Smilax trinervula Miq.	Others
(7S,8R)-4,9,9'-Trihydroxy-3,3',5-trimethoxy-8,4'-oxyneolignan 4-O-β-D-glucopyranoside (5) is a lignan compound that can be isolated from Smilax trinervula .

HY-B0927

Hydrastine (-)-β-Hydrastine; (1R,9S)-β-Hydrastine	Alkaloids Piperidine Alkaloids Classification of Application Fields Ranunculaceae Other Diseases Plants Disease Research Fields	Tyrosine Hydroxylase Dopamine Receptor OAT
Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage .

HY-B0927R

Hydrastine (Standard) (-)-β-Hydrastine (Standard); (1R,9S)-β-Hydrastine (Standard)	Alkaloids Piperidine Alkaloids Ranunculaceae Plants	Reference Standards Tyrosine Hydroxylase Dopamine Receptor OAT
Hydrastine (Standard) is the analytical standard of Hydrastine (HY-B0927). This product is intended for research and analytical applications. Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC₅₀=20.7 μM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC₅₀=6.6 μM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinson's disease-related dopaminergic neuronal damage .

HY-107579R

Acifran (Standard) AY 25712 (Standard)	Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Reference Standards GPR109A
(2S,5R,6R)-Ticarcillin (disodium) (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin (disodium). This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.

HY-N5136

25(R,S)-Ruscogenin	Liliaceae Microorganisms Classification of Application Fields Source classification Liriope platyphylla Wang et Tang Plants Disease Research Fields Steroids Cancer	Apoptosis PI3K Akt mTOR
Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway . And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su

HY-N10678

R-30-Hydroxygambogic acid	Ketones, Aldehydes, Acids Source classification Guttiferae Plants Garcinia hanburyi Hook. f.	Others
R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC₅₀ values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .

Cat. No.	Product Name	Chemical Structure

HY-12772S2

(2R,4S)-Hydroxy Itraconazole-d5
(2R,4S)-Hydroxy Itraconazole-d₅ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole .

HY-126047AS

(R,S)-Anatabine-d4
(R,S)-Anatabine-d4 is a deuterated labeled (R,S)-Anatabine (HY-126047A). (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .

HY-158207S

(+)-Nebivolol-d4
(S,R,R,R)-Nebivolol-d₄ is deuterium labeled (S,R,R,R)-Nebivolol .

HY-A0021AS

(S,R)-Palonosetron-d3 hydrochloride
(S,R)-Palonosetron-d₃ (hydrochloride) is the deuterium labeled (S,R)-Palonosetron hydrochloride .

HY-12772S1

(2R,4S)-Hydroxy Itraconazole-d8
(2R,4S)-Hydroxy Itraconazole-d₈ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole[1].

HY-B0395DS

(1R,2S,7R)-Sitafloxacin-d4 hydrochloride
(1R,2S,7R)-Sitafloxacin-d₄ hydrochloride is deuterium labeled (1R,2S,7R)-Sitafloxacin hydrochloride (HY-B0395D). (R)-Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC₅₀ of 0.18 μg/mL of DNA gyrase .

HY-118828AS

(9S,13R)-12-Oxo phytodienoic acid-d5
(9S,13R)-12-OPDA-d₅ ((9S,13R)-12-OPDA-d₅) is an isotopic label of (9S,13R)-12-oxyphytodienoic acid. (9S,13R)-12-Oxophytodienoic acid is an isomer of 12-oxoPDA (HY-118828). (9S,13R)-12-Oxo phytodienoic Acid is a lipoxygenase metabolite in green plant leaves .

HY-13623CS

(1R,3S,4R)-ent-Entecavir-13C2,15N
(1R,3S,4R)-ent-Entecavir- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled (1R,3S,4R)-ent-Entecavir .

HY-Z5058S

(3R,5S)-Fluvastatin-d7 sodium
(3R,5S)-Fluvastatin-d₇ (sodium) is the deuterium labeled (3R,5S)-Fluvastatin sodium .

HY-146940S

CER7-2’S,6R-d9
CER7-2’S,6R-d₉ is deuterium labeled CER7-2’S,6R.

HY-W739718

(R,S)-Cotinine-d3 N-Oxide
(R,S)-Cotinine-d₃ N-Oxide is the deuterium labeled (R,S)-Cotinine N-Oxide.

HY-150092S

(2S,3R)-8(9)-EET-d11
(2S,3R)-8(9)-EET-d₁₁ is deuterium-labeled (2S,3R)-8(9)-EET (HY-150092) .

HY-W021425S1

D-Mannosamine-d2 hydrochloride
D-Mannosamine-d₂ (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal-d₂) hydrochloride is a deuterium labeled D-Mannosamine hydrochloride (HY-W021425). D-Mannosamine ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors.

HY-W012864S

(2S,3R)-2,3,4-Trihydroxybutanal-13C
(2S,3R)-2,3,4-Trihydroxybutanal- ¹³C is the ¹³C labeled (2S,3R)-2,3,4-Trihydroxybutanal .

HY-W040240S

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite .

HY-146768S

24(R/S),25-Epoxycholesterol-d6
24(R/S),25-Epoxycholesterol-d₆ is deuterium labeled 24(R/S),25-Epoxycholesterol.

HY-W040240S2

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C-2
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C-2 is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite .

HY-W040240S1

(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one-13C-1
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- ¹³C-1 is the ¹³C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite .

HY-W012864S1

(2S,3R)-2,3,4-Trihydroxybutanal-13C-1
(2S,3R)-2,3,4-Trihydroxybutanal- ¹³C-1 is the ¹³C labeled (2S,3R)-2,3,4-Trihydroxybutanal .

HY-W012864S2

(2S,3R)-2,3,4-Trihydroxybutanal-13C-2
(2S,3R)-2,3,4-Trihydroxybutanal- ¹³C-2 is the ¹³C labeled (2S,3R)-2,3,4-Trihydroxybutanal .

HY-W745349

rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride
rel-(1S,2R)-Dihydro bupropion-d₉ hydrochloride is the deuterium labeled rel-(1S,2R)-Dihydro bupropion hydrochloride .

HY-146787S

7α,24(R/S)-Dihydroxycholestenone-d7
7α,24(R/S)-Dihydroxycholestenone-d₇ is deuterium labeled 7α,24(R/S)-Dihydroxycholestenone.

HY-146784S

7α,24(R/S)-Dihydroxycholesterol-d7
7α,24(R/S)-Dihydroxycholesterol-d₇ is deuterium labeled 7α,24(R/S)-Dihydroxycholesterol.

HY-132451S

(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit
(R,S)-4-Hydroxy Cyclophosphamide-d₄ Preparation Kit is the deuterium labeled (R,S)-4-Hydroxy Cyclophosphamide Preparation Kit. (R,S)-4-Hydroxy Cyclophosphamide is an isomer of 4-Hydroxycyclophosphamide, the active metabolite of the cytotoxic alkylating agent Cyclophosphamide (HY-17420) .

HY-14664CS

(3S,5R)-Fluvastatin-d6 sodium
(3S,5R)-Fluvastatin-d₆ (sodium)?is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC₅₀?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-Z1430S

(3R,4S)-Paroxetine-d4 hydrochloride
Paroxetine EP impurity D-d₄ (hydrochloride) is deuterium labeled (3R,4S)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (Paroxetine Impurity).

HY-14664DS

(3S,5R)-Fluvastatin-d6
(3S,5R)-Fluvastatin-d₆ is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC₅₀?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .

HY-W777138

rel-(1S,2R)-Dihydro bupropion-d9
rel-(1S,2R)-Dihydro bupropion-d₉ is the deuterium labeled rel-(1S,2R)-Dihydro bupropion. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-132672S

(4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d3
(4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d₃ is the deuterium labeled (4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone .

HY-W010143S

(R,S)-Norcotinine-d4
(R,S)-Norcotinine-d₄ is a deuterium labeled compound.

HY-W653721

(R,S)-N-Nitroso anabasine-d4
(R,S)-N-Nitroso anabasine-d₄ is deuterium labeled 3-(1-nitrosopiperidin-2-yl)pyridine .

HY-141788S

rel-4-Nitrobenzyl (2S,4R)-2-(dimethylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate-d6
rel-4-Nitrobenzyl (2S,4R)-2-(dimethylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate-d₆ is the deuterium labeled rel-4-Nitrobenzyl (2S,4R)-2-(dimethylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate .

HY-146708S

((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-15N4 sodium
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹⁵N₄ (sodium) is a ¹⁵N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so

HY-135329S

(1R,3S-)Solifenacin-d5 hydrochloride
(1R,3S-)Solifenacin-d₅ hydrochloride is the deuterium labeled Solifenacin hydrochloride. Solifenacin D₅ hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is a muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively .

HY-17447AS

(1S,2R)-Tranylcypromine-d5 hydrochloride

(1S,2R)-Tranylcypromine-d₅ (hydrochloride) is the deuterium labeled Tranylcypromine hydrochloride . Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC₅₀s of 20.7, 2.3 and 0.95 μM, respectively. Tranylcypromine hydrochloride can be used for the research of depression .

HY-W011090S

((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate-13C9,15N3 sodium
((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- ¹³C₉, ¹⁵N₃ (sodium) is the ¹³C and ¹⁵N labeled Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate .

HY-A0052S

(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4
(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d₄ is deuterated labeled (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide.

HY-139968S

13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d₄ is the deuterium labeled 13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1 .

HY-157571S

N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8
N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8 is a stable isotope of hydrazine impurities in Sonidegib (HY-16582A).

HY-14794AS

Levomilnacipran-d10 hydrochloride

Levomilnacipran-d₁₀ ((1S,2R)-Milnacipran-d₁₀) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC₅₀ values of 10.5 nM and 19.0 nM, and K_i values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .

HY-B0168BS

Levomilnacipran-d5 hydrochloride

Levomilnacipran-d5 ((1S,2R)-Milnacipran-d5) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC₅₀ values of 10.5 nM and 19.0 nM, and K_i values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .

HY-W766136

Aprepitant Impurity 9-13C2,d2
Aprepitant Impurity 9- ¹³C₂,d₂ (2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenyl-4-[(2-N-methoxycarbonyl)acetamidrazono]morpholine- ¹³C₂,d₂) is the deuterium labeled and ¹³C-labeled Aprepitant Impurity 9 (HY-Z11099).

HY-W711528

3b,5a-Cholic acid-d5
3b,5a-Cholic acid-d₅ is the deuterium labeled (4R)-4-((3S,5R,7R,10S,12S,13R,14S,17R)-3,7,12-Trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (HY-W711534).

HY-W753480

Phenol rutinoside-d5
Phenol rutinoside-d₅ is the deuterium labeled (2S,3R,4R,5R,6R)-2-Methyl-6-(((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-phenoxytetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triol (HY-W725466).

HY-W725464

4-Methylsyringol Gentiobioside-d6
4-Methylsyringol Gentiobioside-d₆ is the deuterium labeled (2S,3R,4S,5S,6R)-2-(2,6-Dimethoxy-4-methylphenoxy)-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol (HY-W725468).

HY-W242887S2

D-Gulose-13C
D-Gulose- ¹³C is the ¹³C labeled (2R,3R,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal .

HY-W242887S3

D-Gulose-1-13C
D-Gulose-1- ¹³C is the ¹³C labeled (2R,3R,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal .

HY-B0105BS

(-)-Ketoconazole-d3
(-)-Ketoconazole-d₃ is deuterium labeled (-)-Ketoconazole. (-)-Ketoconazole ((-)-R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(−)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole).

HY-W717913

Guaiacol-β-D-glucopyranoside-d3
Guaiacol-β-D-glucopyranoside-d₃ is the deuterium labeled (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-methoxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol (HY-W717912).

HY-W759099

3-O-a-d-glucosyl isomaltol-d3
3-O-a-d-glucosyl isomaltol-d₃ is the deuterium labeled 1-(3-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)furan-2-yl)ethan-1-one (HY-W715028).

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