2. Gene
  3. Crbn - cereblon Gene

Crbn - cereblon Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as piL; 2610203G15Rik; 2900045O07Rik

Gene ID: 58799 | Gene type: protein coding

About Crbn

Summary

This gene encodes a protein with a Lon protease domain, a "regulators of G protein-signaling" (RGS)-like domain and a leucine zipper. It has been proposed to regulate the assembly and surface expression of large-conductance calcium-activated potassium channels in brain and to bind thalidomide. In humans mutation in this gene causes autosomal recessive nonsyndromic cognitive disability. In mouse deficiency of this gene serves as a model to study the molecular mechanisms governing learning and memory as they relate to intellectual disability. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]

Crbn Products(2)

mRNA Protein Name
NM_021449.3 NP_067424.2 protein cereblon isoform 1
NM_175357.3 NP_780566.1 protein cereblon isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in locomotory exploration behavior IMP
IMP: Inferred from mutant phenotype
29530986 MGI
involved in negative regulation of large conductance calcium-activated potassium channel activity IMP
IMP: Inferred from mutant phenotype
29530986 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein cereblon

novel lethal

protein PiL

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0003 Lenalidomide Inducer 99.95% Yes
HY-14658 Thalidomide Inducer 99.98% Yes
HY-A0003B Lenalidomide hemihydrate Inducer 99.98% Yes
HY-A0003A Lenalidomide hydrochloride / Unkown
Clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Phase
HY-101291 Iberdomide Inducer 99.54% Phase 3
HY-115997 PROTAC HSP90 degrader BP3 Inhibitor 99.54% Phase 3
HY-130800 Eragidomide 99.86% Phase 2
HY-158101 BMS-986365 Degrader 99.92% Phase 2
HY-146237 Golcadomide Modulator 98.04% Phase 2
HY-153341 CFT1946 Degrader 99.41% Phase 2
HY-145925B CFT8634 Inhibitor 98.10% Phase 1
HY-145776 ALV1 Inhibitor 98.62% Phase 1
Pre-clinical Phase
Bioactive Molecules (450)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114421 FKBP12 PROTAC dTAG-13 Degrader 99.89% Unkown
HY-101488 CC-885 99.85% Unkown
HY-160695 PT-179 99.91% Unkown
HY-12214A NVP-2 99.60% Unkown
HY-134582 dCBP-1 Inhibitor 99.44% Unkown
HY-148333 MS177 98.00% Unkown
HY-132199 SJ6986 Degrader 98.00% Unkown
HY-144998 NVP-DKY709 Inhibitor 98.86% Unkown
HY-123937 THAL-SNS-032 Inhibitor 99.16% Unkown
HY-129603 SI-109 Inhibitor 99.91% Unkown
HY-153321 NX-5948 Degrader 99.33% Unkown
HY-141881 PROTAC-O4I2 99.66% Unkown
HY-130665 TL12-186 Inhibitor 99.63% Unkown
HY-123941 FKBP12 PROTAC dTAG-7 Inhibitor 99.07% Unkown
HY-155008 PROTAC HK2 Degrader-1 Degrader 98.98% Unkown
HY-163410 AU-24118 Degrader 99.10% Unkown
HY-41547 Thalidomide 4-fluoride Inducer 99.92% Unkown
HY-145765 JQAD1 98.24% Unkown
HY-150608 PROTAC STING Degrader-1 Inhibitor 98.26% Unkown
HY-103597 Thalidomide-O-COOH 99.85% Unkown
HY-137206 ALV2 98.07% Unkown
HY-139344 FC-11 Degrader 99.95% Unkown
HY-W077589 Lenalidomide-5-aminomethyl hydrochloride 98.77% Unkown
HY-125876 PROTAC Bcl2 degrader-1 Inhibitor 99.80% Unkown
HY-133120 INY-03-041 Inhibitor 99.74% Unkown
HY-23095 Thalidomide-5-OH Inducer 99.65% Unkown
HY-103596 Thalidomide-4-OH Inducer 99.85% Unkown
HY-126534A Abemaciclib metabolite M18 hydrochloride Inhibitor 98.18% Unkown
HY-151902 SJ988497 98.05% Unkown
HY-114420 AP1867-2-(carboxymethoxy) Inhibitor 99.85% Unkown
HY-131717 Thalidomide-NH-CH2-COOH Inducer 98.07% Unkown
HY-145696 SJ10542 Inhibitor 99.92% Unkown
HY-156698 HJM-561 Degrader 98.64% Unkown
HY-43722 Lenalidomide-Br 99.86% Unkown
HY-136262 CRBN-6-5-5-VHL Degrader 99.45% Unkown
HY-133137 SJF620 Inhibitor 98.98% Unkown
HY-147158 ZXH-1-161 98.43% Unkown
HY-158113 CBPD-409 Degrader 98.97% Unkown
HY-161574 LLC0424 Inhibitor 98.42% Unkown
HY-148369 U7D-1 99.68% Unkown
HY-128845 PROTAC CRBN Degrader-1 Degrader 99.84% Unkown
HY-145282 MS170 Inhibitor 99.72% Unkown
HY-130988 Ipatasertib-NH2 99.64% Unkown
HY-14658A (S)-Thalidomide Inducer 99.52% Unkown
HY-111594 Homo-PROTAC cereblon degrader 1 99.43% Unkown
HY-131318 Lenalidomide-I 99.90% Unkown
HY-133144 Lenalidomide-OH 99.48% Unkown
HY-153803 GBD-9 Degrader 99.76% Unkown
HY-132857A ZXH-4-130 TFA 99.71% Unkown
HY-W072954 Lenalidomide-5-Br 99.87% Unkown
HY-133557 XZ739 99.06% Unkown
HY-W440247 CRBN ligand-109 ≥98.0% Unkown
HY-115881 SR-1114 99.04% Unkown
HY-148290 KTX-951 Degrader 98.03% Unkown
HY-149843 LC-MB12 99.23% Unkown
HY-130296 Palbociclib-propargyl 95.23% Unkown
HY-139539 Thalidomide-5-COOH Inducer 99.94% Unkown
HY-130714 TD-165 Inhibitor 99.41% Unkown
HY-130504 Propargyl-PEG1-acid ≥97.0% Unkown
HY-139186 PROTAC KRAS G12C degrader-1 99.15% Unkown
HY-156591 PROTAC MLKL Degrader-1 Degrader 99.76% Unkown
HY-159098 dWIZ-1 Degrader / Unkown
HY-W093272 Thalidomide-5,6-F Inducer 99.84% Unkown
HY-W244657 3-(6-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 98.77% Unkown
HY-122725B Lenalidomide-C5-NH2 hydrochloride 98.44% Unkown
HY-158239 MS181 Inhibitor 98.36% Unkown
HY-138881 Lenalidomide-6-F 99.63% Unkown
HY-168593 PROTAC KDM3 degrader-1 99.07% Unkown
HY-122653A CCT367766 formic 98.02% Unkown
HY-136688 MI-389 99.34% Unkown
HY-149845 PROTAC GSK-3β Degrader-1 Degrader 98.16% Unkown
HY-150616 SJPYT-195 99.41% Unkown
HY-153166 PT-65 Degrader 98.4% Unkown
HY-158045 PROTAC PARP1 degrader-1 Inhibitor 99.86% Unkown
HY-163815 CDK2 degrader 2 Degrader 99.51% Unkown
HY-W076696 3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione 98.57% Unkown
HY-157570 Anti-inflammatory agent 70 Degrader 97.00% Unkown
HY-114406 TD-106 99.81% Unkown
HY-130683 Lenalidomide-propargyl-C2-NH2 hydrochloride 98.04% Unkown
HY-130737 Pomalidomide 4'-alkylC5-acid 98.78% Unkown
HY-130952 Thalidomide-O-C8-COOH Inducer 97.44% Unkown
HY-133120A INY-03-041 trihydrochloride Inhibitor 99.27% Unkown
HY-122830 DD-03-171 Degrader 98.72% Unkown
HY-123215 CC-17369 98.68% Unkown
HY-123324 Pomalidomide-5-OH 99.46% Unkown
HY-126457 Thalidomide-propargyl Inducer 99.97% Unkown
HY-130713 Thalidomide-C2-amido-C2-COOH Inducer 98.45% Unkown
HY-130716 Thalidomide-NH-C10-COOH Inducer 97.50% Unkown
HY-138040 CRBN modulator-1 98.00% Unkown
HY-147099 dTAG-47-NEG 97.8% Unkown
HY-162704 JMV7048 Degrader 99.12% Unkown
HY-171139 PROTAC HDAC6 degrader 2 Inhibitor 99.80% Unkown
HY-W249500 2-Methoxyphenyl dihydrouracil 95.11% Unkown
HY-115446A Lenalidomide-C4-NH2 hydrochloride 98.85% Unkown
HY-131232 Desmorpholinyl Navitoclax-NH-Me Inhibitor 98.64% Unkown
HY-131295 PD0325901-O-C2-dioxolane Inhibitor 98.62% Unkown
HY-137340 WH-10417-099 98.14% Unkown
HY-147858 PROTAC EGFR degrader 7 99.99% Unkown
HY-161128 Lenalidomide 4'-PEG1-amine dihydrochloride 98.42% Unkown
HY-161741 VinclozolinM2-2204 Degrader 98.00% Unkown
HY-W129872 Thalidomide-5-CH2-NH2 hydrochloride Inducer 98.55% Unkown
HY-W1004786 CRBN ligand-13 97.94% Unkown
HY-129608 Lenalidomide-acetylene-C5-COOH 99.26% Unkown
HY-131159 Thalidomide-O-C8-Boc Inducer 95.12% Unkown
HY-130991 K-Ras ligand-Linker Conjugate 6 / Unkown
HY-141481 DP-C-4 Inhibitor 98.15% Unkown
HY-126534 Abemaciclib metabolite M18 Inhibitor 98.01% Unkown
HY-147858A PROTAC EGFR degrader 7 diTFA 99.19% Unkown
HY-155260 Pomalidomide-5-C4-NH2 hydrochloride 98.63% Unkown
HY-155262 Pomalidomide-5-C6-NH2 hydrochloride 98.46% Unkown
HY-155268 Pomalidomide-5-C12-NH2 hydrochloride 98.07% Unkown
HY-160241 Lenalidomide-C5-acid 96.36% Unkown
HY-161536 PROTAC EGFR degrader 9 98.35% Unkown
HY-161633 PROTAC EGFR degrader 11 Degrader 99.20% Unkown
HY-162014 WDR5 degrader-1 Degrader 98.00% Unkown
HY-163757 PROTAC PD-L1 degrader-1 Inhibitor / Unkown
HY-W145436 Thalidomide-Piperazine 5-fluoride hydrochloride Inducer 98.91% Unkown
HY-W342590 CRBN ligand-9 ≥98.0% Unkown
HY-W584518 Thalidomide-5-O-CH2-COOH Inducer 95.02% Unkown
HY-130682 Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride / Unkown
HY-136160 Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Inducer 99.12% Unkown
HY-145226 XY-06-007 Inhibitor 98.9% Unkown
HY-170428 IPS-06061 Degrader / Unkown
HY-130707 K-Ras ligand-Linker Conjugate 3 / Unkown
HY-130823 K-Ras ligand-Linker Conjugate 5 99.79% Unkown
HY-133137A SJF620 hydrochloride Inhibitor 99.28% Unkown
HY-137465 CG428 Degrader 98.26% Unkown
HY-112811 PROTAC CDK9 degrader-2 Inhibitor / Unkown
HY-114407 TD-428 Inhibitor 98.81% Unkown
HY-126534S Abemaciclib metabolite M18-d8 Inhibitor 98.47% Unkown
HY-131887 Pomalidomide-C6-COOH 98.02% Unkown
HY-132856 Lenalidomide-C5-amido-Boc 95.10% Unkown
HY-139336 Pomalidomide-C5-azide 97.46% Unkown
HY-139540 Pomalidomide-6-OH 98.09% Unkown
HY-139548 Thalidomide-5-methyl Inducer 99.87% Unkown
HY-143286A PF15 TFA Degrader 99.72% Unkown
HY-14658S Thalidomide-d4 Inducer 98.00% Unkown
HY-150839 E3 ligase Ligand PG 99.94% Unkown
HY-158381 PROTAC PTP1B degrader 1 Degrader 99.37% Unkown
HY-161129 Lenalidomide 4'-PEG2-amine dihydrochloride 98.96% Unkown
HY-163938 PROTAC erf3a Degrader-1 99.44% Unkown
HY-168614 MGD-4 Degrader / Unkown
HY-168615 MGD-28 Degrader 99.73% Unkown
HY-173097 (S,R,S)-AHPC-Boc derivative 1 Degrader 98.56% Unkown
HY-173357 TYD-68 / Unkown
HY-44063 Thalidomide-NH-PEG3-NH-Boc Inducer 97.20% Unkown
HY-A0003S Lenalidomide-d5 Inducer 99.32% Unkown
HY-W457950 Thalidomide-5-propargyl Inducer 95.87% Unkown
HY-W998345 SMART1 Inhibitor 99.87% Unkown
HY-130949B Thalidomide-4-O-C7-NH2 hydrochloride 99.80% Unkown
HY-149561 Thalidomide-5-O-C4-NH2 hydrochloride 99.98% Unkown
HY-149570 Thalidomide-5-O-C13-NH2 hydrochloride 99.93% Unkown
HY-149576 Thalidomide-4-O-C14-NH2 hydrochloride 99.85% Unkown
HY-160244 Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride 98.08% Unkown
HY-122725A Lenalidomide-C5-NH2 TFA 98.94% Unkown
HY-129775 K-Ras ligand-Linker Conjugate 1 / Unkown
HY-129776 K-Ras ligand-Linker Conjugate 2 / Unkown
HY-130988A Ipatasertib-NH2 dihydrochloride / Unkown
HY-141486 (Rac)-PROTAC PARP/EGFR ligand 1 / Unkown
HY-145281 MS98 Inhibitor / Unkown
HY-172736 BMS-986458 Degrader / Unkown
HY-122653 CCT367766 / Unkown
HY-130822 K-Ras ligand-Linker Conjugate 4 98.76% Unkown
HY-130981 FN-1501-propionic acid / Unkown
HY-171334A P1D-34 / Unkown
HY-130612 PROTAC BRD2/BRD4 degrader-1 Inhibitor / Unkown
HY-130963B Thalidomide-4-O-C10-NH2 hydrochloride 95.57% Unkown
HY-130965B Thalidomide-PEG3-NH2 hydrochloride Inducer 98.02% Unkown
HY-131717A Thalidomide-NH-CH2-COOH TFA / Unkown
HY-131875 Pomalidomide 4'-alkylC3-acid ≥98.0% Unkown
HY-132288 Pom-8PEG 95.09% Unkown
HY-132857 ZXH-4-130 / Unkown
HY-132862 ZXH-4-137 Chemical / Unkown
HY-132944 (R)-Pomalidomide-pyrrolidine Chemical / Unkown
HY-138882 Lenalidomide-4-aminomethyl / Unkown
HY-138882A Lenalidomide-4-aminomethyl hydrochloride 90.88% Unkown
HY-139541 Pomalidomide-5-O-CH3 / Unkown
HY-139542 Pomalidomide-6-O-CH3 / Unkown
HY-139543 Thalidomide-5-PEG2-Cl Inducer 96.57% Unkown
HY-139544 Thalidomide-5-propoxyethanamine Inducer / Unkown
HY-139545 Thalidomide-4-C3-NH2 hydrochloride Inducer / Unkown
HY-139546 Thalidomide-5-propargyne-NH2 hydrochloride Inducer / Unkown
HY-139547 Thalidomide-5,6-Cl Inducer / Unkown
HY-139549 Thalidomide-benzo Inducer / Unkown
HY-139996 Pomalidomide-C5-Dovitinib / Unkown
HY-139997 DDC-01-163 Degrader / Unkown
HY-143286 PF15 Inhibitor / Unkown
HY-143435 AG6033 Inducer / Unkown
HY-145925C (S,R)-CFT8634 Inhibitor / Unkown
HY-148275 KTX-955 Inhibitor / Unkown
HY-148276 KTX-497 / Unkown
HY-148277 KTX-612 / Unkown
HY-148662 Pomalidomide-PEG5-C2-NH2 hydrochloride / Unkown
HY-150799 CRBN ligand-1 / Unkown
HY-151071 TMX-3013 Inhibitor / Unkown
HY-151886 NU223612 Inhibitor / Unkown
HY-153337 Pomalidomide-C11-NH2 / Unkown
HY-153337A Pomalidomide-C11-NH2 hydrochloride / Unkown
HY-153959 Thalidomide-O-amido-C11-COOH / Unkown
HY-155072 PROTAC BTK Degrader-5 Degrader / Unkown
HY-155258 Pomalidomide-PEG7-NH2 hydrochloride 97.53% Unkown
HY-155259 Pomalidomide-5-C3-NH2 hydrochloride 96.02% Unkown
HY-155261 Pomalidomide-5-C5-NH2 hydrochloride / Unkown
HY-155263 Pomalidomide-5-C7-NH2 hydrochloride / Unkown
HY-155264 Pomalidomide-5-C8-NH2 hydrochloride / Unkown
HY-155265 Pomalidomide-5-C9-NH2 hydrochloride 98.68% Unkown
HY-155266 Pomalidomide-5-C10-NH2 hydrochloride 95.00% Unkown
HY-155267 Pomalidomide-5-C11-NH2 hydrochloride 98.20% Unkown
HY-155269 Pomalidomide-5-C13-NH2 hydrochloride / Unkown
HY-155270 Pomalidomide-5-C14-NH2 hydrochloride / Unkown
HY-156164 Thalidomide-5-NH-PEG2-NH2 hydrochloride Inducer / Unkown
HY-156170 Thalidomide-5-NH-PEG5-NH2 hydrochloride Inducer / Unkown
HY-156726 Pomalidomide-amino-PEG4-C4-Cl / Unkown
HY-157426 GSPT1 degrader-3 Degrader / Unkown
HY-157510 Thalidomide-O-C3-azide / Unkown
HY-157511 Thalidomide-O-C5-azide / Unkown
HY-157515 Thalidomide 4'-ether-PEG2-azide / Unkown
HY-157587 E3 ligase Ligand-Linker Conjugate 29 / Unkown
HY-157588 (S)-Thalidomide-Piperazine-CH2-Pyrrolidine-C2-OH Inducer / Unkown
HY-157594 E3 ligase Ligand-Linker Conjugate 37 / Unkown
HY-157595 E3 ligase Ligand-Linker Conjugate 38 / Unkown
HY-157599 E3 ligase Ligand-Linker Conjugate 65 / Unkown
HY-157600 E3 ligase Ligand-Linker Conjugate 66 / Unkown
HY-157635 E3 Ligase Ligand-linker Conjugate 92 / Unkown
HY-157636 E3 Ligase Ligand-linker Conjugate 93 / Unkown
HY-157637 E3 Ligase Ligand-linker Conjugate 94 / Unkown
HY-157747 E3 Ligase Ligand-linker Conjugate 99 / Unkown
HY-157748 E3 Ligase Ligand-linker Conjugate 100 / Unkown
HY-157756 E3 Ligase Ligand-linker Conjugate 104 / Unkown
HY-157757 E3 Ligase Ligand-linker Conjugate 105 / Unkown
HY-157758 (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-CH2-COO-C(CH3)3 Inducer / Unkown
HY-157759 (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH Inducer / Unkown
HY-157760 (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH Inducer / Unkown
HY-157761 E3 Ligase Ligand-linker Conjugate 106 / Unkown
HY-157767 Abd110 Inhibitor / Unkown
HY-158062 LC-1-40 / Unkown
HY-158152 PROTAC CRBN ligand-2 / Unkown
HY-158325 PROTAC FLT-3 degrader 4 / Unkown
HY-159087 RGB110 / Unkown
HY-160017 Pomalidomide-5'-C8-acid / Unkown
HY-161130 Lenalidomide 4'-PEG3-amine dihydrochloride / Unkown
HY-161131 Lenalidomide 4'-alkyl-C3-azide / Unkown
HY-161183 (S)-Thalidomide-O-(1S,3r)-C4H4-N(Me)-Pip-C2-O-C-boc Inducer / Unkown
HY-161184 Deoxy-thalidomide-piperidine-C-piperazine-C2-OH Inducer / Unkown
HY-161186 Thalidomide-piperidine-C-azetidine-C2-O-C-boc Inducer / Unkown
HY-161187 Thalidomide-piperidine-1,6-diazaspiro[3.3]heptane-boc Inducer / Unkown
HY-161188 Thalidomide-O-C4H4-N(Me)-piperidine-C2-OH Inducer / Unkown
HY-161189 Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C-boc Inducer / Unkown
HY-161190 Thalidomide-piperidine-C-2,6-diazaspiro[3.3]heptane-C2-OH Inducer / Unkown
HY-161191 Thalidomide-azetidine-piperazine-C2-O-C2-OH Inducer / Unkown
HY-161192 Thalidomide-O-C4H4-N(Me)-piperidine-C-boc Inducer / Unkown
HY-161193 Thalidomide-piperazine-(R)-C-pyrrolidine-C-boc Inducer / Unkown
HY-161195 Deoxy-thalidomide-piperidine-C-piperazine-C-boc Inducer / Unkown
HY-161196 Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C-boc Inducer / Unkown
HY-161197 Thalidomide-2,6-diazaspiro[3.4]octane-C-piperidine-C2-O-C2-OH Inducer / Unkown
HY-161198 Thalidomide-azetidine-pyrrolidine-C-piperidine-C-boc Inducer / Unkown
HY-161199 Thalidomide-azetidine-pyrrolidine-C-piperidine-C2-OH Inducer / Unkown
HY-161200 Thalidomide-piperazine-C-azetidine-C2-OH Inducer / Unkown
HY-161201 Thalidomide-piperazine-pyrimidine-piperazine-C-boc Inducer / Unkown
HY-161202 Thalidomide-piperidine-O-piperidine-C2-OH Inducer / Unkown
HY-161203 Thalidomide-azetidine-piperazine-C2-O-C-boc Inducer / Unkown
HY-161204 Thalidomide-O-C4H4-N(Me)-piperidine-boc Inducer / Unkown
HY-161205 Thalidomide-PIP-(R)C-pyrrolidine-boc Inducer / Unkown
HY-161206 Thalidomide-Pip-C-Pip-O-C-boc Inducer / Unkown
HY-161208 Deoxy-thalidomide-Pip-C-PIP-boc Inducer / Unkown
HY-161209 Thalidomide-2,6-diazaspiro[3.4]octane-C-Pip-boc Inducer / Unkown
HY-161210 Thalidomide-azetidine-C-PIP-C-boc Inducer / Unkown
HY-161250 Pomalidomide-NH-PEG6-amide-C2-CPI-1612 / Unkown
HY-161632 PROTAC EGFR degrader 10 Degrader / Unkown
HY-161654 PROTAC SOS1 degrader-10 / Unkown
HY-161668 Ru-Poma / Unkown
HY-161696 AN5777 Inducer / Unkown
HY-162180 E3 Ligase Ligand-linker Conjugate 2 / Unkown
HY-162181 E3 Ligase Ligand-linker Conjugate 5 / Unkown
HY-162182 E3 Ligase Ligand-linker Conjugate 7 / Unkown
HY-162183 E3 Ligase Ligand-linker Conjugate 9 / Unkown
HY-162184 E3 ligase Ligand-Linker Conjugate 11 / Unkown
HY-162185 E3 Ligase Ligand-linker Conjugate 12 / Unkown
HY-162186 E3 Ligase Ligand-linker Conjugate 13 / Unkown
HY-162187 E3 Ligase Ligand-linker Conjugate 14 / Unkown
HY-162189 E3 Ligase Ligand-linker Conjugate 16 / Unkown
HY-162190 E3 Ligase Ligand-linker Conjugate 17 / Unkown
HY-162191 E3 Ligase Ligand-linker Conjugate 18 / Unkown
HY-162192 E3 Ligase Ligand-linker Conjugate 20 / Unkown
HY-162194 E3 Ligase Ligand-linker Conjugate 28 / Unkown
HY-162195 E3 ligase Ligand-Linker Conjugate 34 / Unkown
HY-162196 E3 ligase Ligand-Linker Conjugate 39 / Unkown
HY-162197 E3 ligase Ligand-Linker Conjugate 41 / Unkown
HY-162198 E3 ligase Ligand-Linker Conjugate 43 / Unkown
HY-162199 E3 Ligase Ligand-linker Conjugate 45 / Unkown
HY-162200 E3 Ligase Ligand-linker Conjugate 47 / Unkown
HY-162203 E3 Ligase Ligand-linker Conjugate 51 / Unkown
HY-162204 E3 Ligase Ligand-linker Conjugate 54 / Unkown
HY-162205 E3 Ligase Ligand-linker Conjugate 55 / Unkown
HY-162206 E3 Ligase Ligand-linker Conjugate 58 / Unkown
HY-162538 LC-MI-3 / Unkown
HY-162702 AZ'3137 Degrader 99.90% Unkown
HY-163168 aTAG 4531 Inhibitor / Unkown
HY-163210 Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride / Unkown
HY-163221 (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc Inducer / Unkown
HY-163225 (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc Inducer / Unkown
HY-163226 (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc Inducer / Unkown
HY-163227 (1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc Inducer / Unkown
HY-163229 (1r,4r)-Thalidomide-piperidine-N(Me)-CH-cyclohexane-NH-Boc Inducer / Unkown
HY-163230 (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc Inducer / Unkown
HY-163232 Phthalimidinoglutarimide-piperidine-NH-Boc / Unkown
HY-163233 Phthalimidinoglutarimide-5-piperazine / Unkown
HY-163234 Phthalimidinoglutarimide-piperidine-NH2 / Unkown
HY-163236 Thalidomide-piperidine-O-azetidine-acetic acid Inducer / Unkown
HY-163237 Thalidomide-piperidine-O-azetidineethanol Inducer / Unkown
HY-163238 Thalidomide-azetidine-CH-piperazineethanol Inducer / Unkown
HY-163239 (R)-Thalidomide-piperazine-pyrrolidineethanol Inducer / Unkown
HY-163851 PROTAC Vif degrader-1 Inhibitor / Unkown
HY-163922 CRBN ligand-1-piperidine-Me / Unkown
HY-164906 TMX-2138 Degrader / Unkown
HY-168274 PROTAC TRIB2 degrader-1 Inducer / Unkown
HY-168867 RD-23 / Unkown
HY-168869 Tamoxifen-PEG-Clozapine Degrader / Unkown
HY-168910 PROTAC c-Met degrader-3 Degrader / Unkown
HY-168964 Ethanolamine-Thalidomide-4-OH / Unkown
HY-169077 IKZF3 degrader 1 Degrader / Unkown
HY-169082 JQ-1 (carboxylic acid)-NH-C2-NH-COOH / Unkown
HY-169232 PCC16 chloride Degrader / Unkown
HY-169235 DHHC3 degrader 1 / Unkown
HY-169356 Acepromazine-OTs / Unkown
HY-169362 Lenalidomide-Pip-butyn / Unkown
HY-169401 L321-NH-C3-PEG3-C1-NH2 / Unkown
HY-169954 CRBN ligand-10 / Unkown
HY-169989 CRBN ligand-11 / Unkown
HY-170058 CRBN ligand-12 / Unkown
HY-170076 CRBN ligand-17 / Unkown
HY-170335 PROTAC c-Met degrader-2 Degrader / Unkown
HY-170390 AB3067 Degrader / Unkown
HY-170449 E3 ligase Ligand 48 / Unkown
HY-170601 PROTAC JNK1-targeted-1 Degrader / Unkown
HY-170673 E3 Ligase Ligand-linker Conjugate 156 / Unkown
HY-170820 XYD049 / Unkown
HY-170869 PROTAC FGFR1 degrader-1 Degrader / Unkown
HY-170996 ROR1 ligand-1 Degrader / Unkown
HY-172368 PROTAC CARM1/IKZF3 degrader-1 / Unkown
HY-172590 LZ-07 / Unkown
HY-172593 E3 Ligase Ligand-linker Conjugate 182 / Unkown
HY-172770 KMG-1068 / Unkown
HY-172827 PROTAC BRD4 Degrader-30 Degrader / Unkown
HY-172931 DEG-35 Degrader / Unkown
HY-172949 E3 Ligase Ligand-linker Conjugate 187 / Unkown
HY-172954 Androgen receptor ligand 1 / Unkown
HY-173154 NK7-902 Degrader / Unkown
HY-173266 TO-1187 Degrader / Unkown
HY-173359 TYK2 ligand 2 Ligand / Unkown
HY-173414 PROTAC STING degrader-3 / Unkown
HY-173437 CW-2 Degrader / Unkown
HY-173523 KI-CDK9d-32 / Unkown
HY-173631 (S)-dHTC1 Degrader / Unkown
HY-174087 Thalidomide-4-OH-C11-OH / Unkown
HY-176125 E3 Ligase Ligand-linker Conjugate 184 / Unkown
HY-176128 BWA-6047 Degrader / Unkown
HY-176166 PD-M6 Degrader / Unkown
HY-176180 PROTAC STING degrader-4 / Unkown
HY-176181 Thalidomide-4-PEG4-OTs Chemical / Unkown
HY-176425 E3 Ligase Ligand-linker Conjugate 186 / Unkown
HY-176428 PROTAC MNK1 degrader-1 / Unkown
HY-176430 Lenalidomide-amide-pimelic acid / Unkown
HY-176449 PROTAC BRD4 Degrader-32 Inhibitor / Unkown
HY-176457 ZS3-046 / Unkown
HY-42771 Thalidomide-4-O-CH2-COO(t-Bu) Inducer / Unkown
HY-A0003S2 Lenalidomide-13C5,15N Inducer / Unkown
HY-N12876 (18α)-Oleanolic acid / Unkown
HY-RS03143 CRBN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W077589A Lenalidomide-5-aminomethyl / Unkown
HY-W584513 Thalidomide-NH-(CH2)2-NH-Boc Inducer / Unkown
HY-W584514 Thalidomide-NH-(CH2)2-NH2 TFA Inducer / Unkown
HY-W584515 Thalidomide-NH-(CH2)3-NH-Boc Inducer / Unkown
HY-W584516 Thalidomide-5-NH-CH2-COO(t-Bu) Inducer / Unkown
HY-W584517 Thalidomide-5-O-CH2-COO(t-Bu) Inducer / Unkown
HY-W584520 Thalidomide-4-NH-PEG1-NH-Boc Inducer / Unkown
HY-W584521 Thalidomide-4-NH-PEG1-NH2 TFA Inducer / Unkown
HY-W584522 Thalidomide-4-NH-PEG1-COO(t-Bu) Inducer / Unkown
HY-W584523 Thalidomide-4-NH-PEG1-COOH TFA Inducer / Unkown
HY-W584524 Thalidomide-4-NH-PEG2-COO(t-Bu) Inducer / Unkown
HY-W760183 EM12-SO2F / Unkown
HY-139332 Pomalidomide 4'-PEG6-azide / Unkown
HY-139333 Pomalidomide 4'-PEG5-azide / Unkown
HY-139339 Pomalidomide 4'-alkylC6-azide / Unkown
HY-139341 Pomalidomide 4'-alkylC3-azide / Unkown
HY-139343 Pomalidomide 4'-alkylC2-azide / Unkown
HY-149559 Thalidomide-5-O-C2-NH2 hydrochloride 98.01% Unkown
HY-149560 Thalidomide-5-O-C3-NH2 hydrochloride 99.08% Unkown
HY-149562 Thalidomide-5-O-C5-NH2 hydrochloride / Unkown
HY-149563 Thalidomide-5-O-C6-NH2 hydrochloride / Unkown
HY-149564 Thalidomide-5-O-C7-NH2 hydrochloride 98.13% Unkown
HY-149565 Thalidomide-5-O-C8-NH2 hydrochloride / Unkown
HY-149566 Thalidomide-5-O-C9-NH2 hydrochloride 99.59% Unkown
HY-149567 Thalidomide-5-O-C10-NH2 hydrochloride 99.37% Unkown
HY-149568 Thalidomide-5-O-C11-NH2 hydrochloride / Unkown
HY-149569 Thalidomide-5-O-C12-NH2 hydrochloride 99.90% Unkown
HY-149571 Thalidomide-5-O-C14-NH2 hydrochloride 97.70% Unkown
HY-149572 Thalidomide-4-O-C9-NH2 hydrochloride / Unkown
HY-149573 Thalidomide-4-O-C11-NH2 hydrochloride 99.94% Unkown
HY-149574 Thalidomide-4-O-C12-NH2 hydrochloride 95.57% Unkown
HY-149575 Thalidomide-4-O-C13-NH2 hydrochloride 99.75% Unkown
HY-155255 Thalidomide-5-PEG2-NH2 hydrochloride / Unkown
HY-155256 Thalidomide-5-PEG6-NH2 hydrochloride / Unkown
HY-155257 Thalidomide-5-PEG7-NH2 hydrochloride / Unkown
HY-156159 Thalidomide-NH-C9-NH2 hydrochloride / Unkown
HY-156160 Thalidomide-NH-C10-NH2 hydrochloride / Unkown
HY-156161 Thalidomide-NH-C13-NH2 hydrochloride / Unkown
HY-156162 Thalidomide-NH-C14-NH2 hydrochloride / Unkown
HY-156163 Thalidomide-5-NH-PEG1-NH2 hydrochloride / Unkown
HY-156165 Thalidomide-5-NH-PEG3-NH2 hydrochloride / Unkown
HY-156171 Thalidomide-5-NH-PEG6-NH2 hydrochloride / Unkown
HY-156172 Thalidomide-NH-PEG6-NH2 hydrochloride / Unkown
HY-157514 Thalidomide 4'-ether-PEG1-azide / Unkown
HY-159164 PROTAC CRBN ligand-3 / Unkown
HY-160531 IKZF1-degrader-1 Degrader / Unkown
HY-161134 Lenalidomide 4'-PEG2-azide / Unkown
HY-161538 Lenalidomide-C6-Br / Unkown
HY-161675 Lenalidomide-5-bromopentanamide / Unkown
HY-164391 Pomalidomide-C2-amide-C4-Br / Unkown
HY-164891 EM12-FS / Unkown
HY-169861 PROTAC SMARCA2/4 degrader-37 Degrader / Unkown
HY-170074 CRBN ligand-14 / Unkown
HY-170075 CRBN ligand-16 / Unkown
HY-170095 CRBN ligand-63 / Unkown
HY-170108 CRBN ligand-47 / Unkown
HY-170126 CRBN ligand-74 / Unkown
HY-170127 CRBN ligand-76 / Unkown
HY-170131 CRBN ligand-84 / Unkown
HY-170213 CRBN ligand-183 / Unkown
HY-170350 Pomalidomide-PEG2-OMs / Unkown
HY-171224 CRBN ligand-45 / Unkown
HY-171775 CRBN ligand-184 / Unkown
HY-403544 CbzNH-(C5-O)2-C4-Boc / Unkown
HY-A0003S3 Lenalidomide-d4 Inducer / Unkown
HY-RS16541 Crbn Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22973 Crbn Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W1111714 3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione / Unkown
HY-W586822 N-Methylated pomalidomide 97.86% Unkown
HY-W674436 (S)-Thalidomide-4-OH ≥98.0% Unkown
HY-W888970 3-(4-Bromo-2-fluorophenyl)piperidine-2,6-dione / Unkown
HY-W893194 CRBN ligand-110 / Unkown
HY-W898983 CRBN ligand-181 / Unkown
HY-W898985 CRBN ligand-148 / Unkown
HY-W898987 CRBN ligand-83 / Unkown
HY-W898989 3-(4-Bromo-2-chlorophenyl)piperidine-2,6-dione / Unkown
HY-W898991 CRBN ligand-112 / Unkown
HY-W898997 CRBN ligand-111 / Unkown
HY-W898998 CRBN ligand-164 / Unkown
HY-W899000 CRBN ligand-162 / Unkown
HY-W899002 CRBN ligand-108 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crbn NCBI NCBI:51185