2. PROTAC Stem Cell/Wnt JAK/STAT Signaling
  3. PROTACs STAT
  4. PROTAC STAT6 degrader-1

PROTAC STAT6 degrader-1 (Compound I-2) is a STAT6 PROTAC degrader with a DC50< 1 nM. PROTAC STAT6 degrader-1 can be used for inflammatory and cancers research. Pink: STAT6 ligand (HY-176864); Blue: CRBN ligase ligand (HY-45512); Black: linker

For research use only. We do not sell to patients.

PROTAC STAT6 degrader-1

PROTAC STAT6 degrader-1 Chemical Structure

CAS No. : 3077464-21-9

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PROTAC STAT6 degrader-1 Related Antibodies

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Description

PROTAC STAT6 degrader-1 (Compound I-2) is a STAT6 PROTAC degrader with a DC50< 1 nM. PROTAC STAT6 degrader-1 can be used for inflammatory and cancers research[1]. Pink: STAT6 ligand (HY-176864); Blue: CRBN ligase ligand (HY-45512); Black: linker

IC50 & Target[1]

STAT6

<1 nM (DC50)

Molecular Weight

851.99

Formula

C47H53N11O5
CAS No.
SMILES

CN(C(N1C(CCC(N2)=O)C2=O)=O)C3=C1C=CC=C3CCCN(CC4)CCN4C5=CC=C(C6=C7C(NC(C(N(C)C)=O)=C7)=CC(C8=CCCN(C(CCN9N=NC=C9)=O)C8)=C6)C=C5
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC STAT6 degrader-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC STAT6 degrader-13077464-21-9PROTACsSTATPROTACDegradationSTAT6Inflammatory diseasesCancersA549 cellsInhibitorinhibitorinhibit

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