Lenalidomide 4'-PEG2-amine dihydrochloride

Cat. No.: HY-161129 Purity: 98.96%: Data Sheet
SDS

COA
Handling Instructions
FAQs
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Lenalidomide 4'-PEG2-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC.

For research use only. We do not sell to patients.

Lenalidomide 4'-PEG2-amine dihydrochloride Chemical Structure

CAS No. : 2624336-88-3

Size	Stock	Quantity

Free Sample (0.1 - 0.5 mg)	Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

463.36

Formula

C₁₉H₂₈Cl₂N₄O₅

CAS No.

2624336-88-3

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NC(C(CC1)N2C(C3=C(C2)C(NCCOCCOCCN)=CC=C3)=O)=O.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 70 mg/mL (151.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1581 mL	10.7907 mL	21.5815 mL
5 mM	0.4316 mL	2.1581 mL	4.3163 mL
10 mM	0.2158 mL	1.0791 mL	2.1581 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.96%

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Data Sheet (267 KB) SDS (252 KB)

COA (248 KB) HNMR (300 KB) LCMS (99 KB)

Handling Instructions (2659 KB)

References

[1]. Wang S, et al. Monofunctional intermediates for ligand-dependent target protein degradation. China, WO2017176958A1. 2017-10-12.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1581 mL	10.7907 mL	21.5815 mL	53.9537 mL
	5 mM	0.4316 mL	2.1581 mL	4.3163 mL	10.7907 mL
	10 mM	0.2158 mL	1.0791 mL	2.1581 mL	5.3954 mL
	15 mM	0.1439 mL	0.7194 mL	1.4388 mL	3.5969 mL
	20 mM	0.1079 mL	0.5395 mL	1.0791 mL	2.6977 mL
	25 mM	0.0863 mL	0.4316 mL	0.8633 mL	2.1581 mL
	30 mM	0.0719 mL	0.3597 mL	0.7194 mL	1.7985 mL
	40 mM	0.0540 mL	0.2698 mL	0.5395 mL	1.3488 mL
	50 mM	0.0432 mL	0.2158 mL	0.4316 mL	1.0791 mL
	60 mM	0.0360 mL	0.1798 mL	0.3597 mL	0.8992 mL
	80 mM	0.0270 mL	0.1349 mL	0.2698 mL	0.6744 mL
	100 mM	0.0216 mL	0.1079 mL	0.2158 mL	0.5395 mL