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Results for "

radicals

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (124) Cardiovascular Disease (32) Endocrinology (6) Infection (55) Inflammation/Immunology (161) Metabolic Disease (92) Neurological Disease (82)
Click Chemistry:	Azide (1) Alkynes (1)
Oligonucleotides:	Antioxidants (1) Solvents (2) Preservatives (1) Chelating Agents (1)

514

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

232

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120976

DEPMPO	Biochemical Assay Reagents	Cancer
cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds .

HY-121137

BMPO BocMPO	Others	Others
BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals .

HY-N4177

Rubrofusarin gentiobioside	Others	Metabolic Disease
Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect .

HY-Y0525

AAPH 2,2'-Azodiisobutyramidine dihydrochloride	Reactive Oxygen Species	Inflammation/Immunology
AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis . AAPH decomposes at 37℃ to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis .

HY-D1459

BODIPY 665/676	Fluorescent Dye	Metabolic Disease
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-N9095

Curculigoside C	Others	Neurological Disease
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N8274

Flavidin	Others	Inflammation/Immunology
Flavidin, an aromatic compound, can be isolated from Coelogyne longipe. Flavidin is an antioxidant, and has radical scavenging activity .

HY-N9289

Vitedoin A	Others	Inflammation/Immunology
Vitedoin A is a phenyldihydronaphthalene-type lignan. Vitedoin A has antioxidative activity and radical-scavenging effect. Vitedoin A can be isolated from Vitex negundo .

HY-N8579

Eugenyl benzoate	Others	Inflammation/Immunology
Eugenyl benzoate has the potency for scavenging of DPPH radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors .

HY-117457

BPIC	DNA/RNA Synthesis	Cancer
BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals .

HY-129109

NBD-Pen	Fluorescent Dye	Inflammation/Immunology Cancer
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λ_ex: 470 nm, λ_em: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H₂O₂, ClO ^-, O₂ ^-∙, and ∙OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .

HY-119955

Amflutizole LY-141894	Xanthine Oxidase	Others
Amflutizole (LY-141894) is an inhibitor of xanthine oxidase. Amflutizole abolishes free radical formation and release in cerebral ischemia/reperfusion mice .

HY-106408A

Nelonemdaz potassium Salfaprodil; Neu2000 potassium	iGluR	Neurological Disease
Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death .

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Others	Infection Inflammation/Immunology
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-106408

Nelonemdaz Salfaprodil free base; Neu2000	iGluR	Neurological Disease
Nelonemdaz (Salfaprodil free base) is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz is also a free radical scavenger. Nelonemdaz has excellent neuroprotection against NMDA- and free radical-induced cell death .

HY-N0499A

Cyanidin	Others	Inflammation/Immunology
Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity .

HY-W067572

Stobadine (-)-Stobadine	Reactive Oxygen Species	Cardiovascular Disease
Stobadine is a potent antioxidant and prevents free radical induced alterations in ER membrane fluidity. Stobadine can be used for effective cardio- and neuroprotectants development based on antioxidant or free radical scavenging mechanisms of action .

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Others	Inflammation/Immunology
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

HY-N10985

Xanthone V1a	Others	Inflammation/Immunology Cancer
Xanthone V1a has antioxidant activity against the DPPH radical (IC₅₀: 10.43 µM). Xanthone V1a has cytotoxicity against cancer cells .

HY-N9497

Galactinol	Biochemical Assay Reagents	Others
Galactinol is a biochemical reagent. Galactinol scavenges hydroxyl radicals and protects plant cells from oxidative damage .

HY-129242

Tempone 4-Oxo-Tempo	SOD	Others
Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .

HY-135152

CYPMPO	Reactive Oxygen Species	Cancer
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .

HY-111523

Isomahanine	p38 MAPK Apoptosis Autophagy Caspase	Metabolic Disease
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

HY-114713

POBN 4-POBN	Biochemical Assay Reagents	Others
POBN (4-POBN) is a cell permeable, hydrophilic spin trap that can be used to detect free radical adducts .

HY-N9068

Alterlactone	Fungal	Infection
Alterlactone is an antimicrobial. Alterlactone shows broad antimicrobial activity against bacterial and fungal. Alterlactone has strong radical scavenging activity .

HY-N3596

Cleomiscosin C Aquillochin	Others	Inflammation/Immunology
Cleomiscosin C (Aquillochin) can be isolated from Aquilaria agallocha. Cleomiscosin C has antioxidant activity. Cleomiscosin C inhibits LDL oxidation and free radicals generation .

HY-W087905

2,3-Dimethyl-2,3-diphenylbutane	Biochemical Assay Reagents	Others
2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency .

HY-23033

Tempone-H 1 Publications Verification	Biochemical Assay Reagents	Neurological Disease
Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H .

HY-N7518

Eulophiol	Others	Inflammation/Immunology
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

HY-N1859

3'-O-Methylorobol	Others	Metabolic Disease Inflammation/Immunology
3'-O-Methylorobol, an antioxidant flavonoid, exhibits moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay .

HY-N4168B

Methyl chlorogenate	Others	Cancer
Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis .

HY-N8042

Erigeside I	Others	Others
Erigeside I is a free radical scavenger isolated from Erigeron breviscapus .

HY-N10020

Patulitrin	Lipoxygenase	Inflammation/Immunology
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-114651

Phenazoviridin	Others	Cancer
Phenazoviridin is a free radical scavenger. Phenazoviridin shows strong inhibitory activity against lipid peroxidation in rat brain homogenate and exhibits antihypoxic activity in mice .

HY-W011875

2-Isopropylthioxanthone	Biochemical Assay Reagents	Others
2-Isopropylthioxanthone is a photoinitiator that is widely used in printing ink of packaging materials. 2-Isopropylthioxanthone triggers the radical polymerization of the acrylic component of inks, thus causing the liquid ink film to dry .

HY-W021267

3-Demethylcolchicine	Reactive Oxygen Species	Inflammation/Immunology
3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema .

HY-N9447

Norbergenin 1 Publications Verification	Reactive Oxygen Species	Neurological Disease
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-N10770

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone	Others	Metabolic Disease
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .

HY-N9051

6-Prenylquercetin-3-Me ether	Glycosidase	Inflammation/Immunology Cancer
6-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase .

HY-W015913

Sodium 2-oxopropanoate 5+ Cited Publications Sodium pyruvate	Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease
Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Others	Neurological Disease
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-W020183

γ-Terpinene	Fungal Bacterial	Neurological Disease
γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-N3985

Gyrophoric acid	Others	Cancer
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows *DPPH radical* scavenging** activity with an IC₅₀ value of 105.75 μg/ml .

HY-164159

α-Glucosylrutin	Reactive Oxygen Species	Inflammation/Immunology
α-Glucosylrutin is a potent antioxidant with free radical scavenging activity. Due to its high epidermal bioavailability, α-Glucosylrutin can be used in the study of skin aging .

HY-N8844

2''-O-Galloylquercitrin	Others	Others
2"-O-Galloylquercitrin (Compound 6) is isolated from the natural Acer ginnala. 2"-O-Galloylquercitrin has health benefits. 2"-O-Galloylquercitrin has the activity of free radical scavenger .

HY-W357738

Urease-IN-14	Bacterial Urease	Infection
Urease-IN-14 (compound 15) is an urease inhibitor and antioxidant. Urease-IN-14 shows DPPH radical scavenging and urease inhibitory activities with IC₅₀ values 151.7 μM and 41.6 μM, respectively .

HY-N3847

Eriodictyol-7-O-glucoside Eriodictyol 7-O-β-D-glucoside	Keap1-Nrf2	Metabolic Disease
Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity .

HY-125568

Pyridoxatin	MMP	Others
Pyridoxatin is a free radical scavenger of microbial origin. Pyridoxatin is isolated from a fungus culture identified as Acremonium sp. BX86. Pyridoxatin inhibits lipid peroxidation induced by free radicals in rat liver microsomes free from vitamin E .

HY-N15440

Mutatochrome Citroxanthin	Reactive Oxygen Species Endogenous Metabolite	Inflammation/Immunology Cancer
Mutatochrome (Citroxanthin) is a naturally occurring carotenoid pigment found in certain plants. Mutatochrome has antioxidant property to help protect cells from damage caused by free radicals. Mutatochrome can be used for anti-inflammatory and anticancer study .

HY-N7692

Polyporusterone A	Others	Others
Polyporusterone A is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone A has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

Cat. No.	Product Name

HY-L037

Antioxidant Compound Library

2,068 compounds

Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue damage. Oxidative stress can be responsible for the induction of several diseases, both chronic and degenerative, as well as speeding up body aging process and cause acute pathologies. Antioxidants are a class of compounds able to counteract oxidative stress and mitigate its effects on individuals’ health, gained enormous attention from the biomedical research community. Antioxidants have long been substantial and amenable therapeutic arsenals for multifarious diseases such as AD and cancer.

MCE Antioxidant Compound Library contains 2,068 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS). This library is a useful tool for discovery new antioxidants and oxidative stress research.

HY-L144

Mitochondrial Protection Compound Library

902 compounds

Normal mitochondrial function is critical for maintaining cellular homeostasis because mitochondria produce ATP and are the major intracellular source of free radicals. Cellular dysfunctions induced by intracellular or extracellular insults converge on mitochondria and induce a sudden increase in permeability on the inner mitochondrial membrane, the so-called mitochondrial membrane permeability transition (MMPT). MMPT is caused by the opening of pores in the inner mitochondrial membrane, matrix swelling, and outer membrane rupture. The MMPT is an endpoint to initiate cell death because the pore opening together with the release of mitochondrial cytochrome c activates the apoptotic pathway of caspases.

The normal operation of mitochondrial function is important for maintaining normal cell death and treatment of mitochondrial diseases. MCE offers a unique collection of 902 compounds with identified and potential mitochondrial protective activity. MCE Mitochondrial Protection Compound Library is critical for drug discovery and development.

HY-L178

Radioprotector Library

2,457 compounds

Radiation sickness is a general term for various types and degrees of damage (or disease) occurring in the human body after exposure to ionizing radiation. Although small amounts of ionizing radiation can also cause the body to produce free radicals and ROS, causing oxidative stress, resulting in DNA damage and chromosomal aberration. Radioprotector are compounds with radiation protection that can be used to prevent/protect non-tumor cells from the harmful effects of radiation. Radioprotective compounds can prevent the damage of radioactive substances to the human body and reduce the clinical symptoms of various radioactive diseases. In addition, radioprotectors can protect normal cells from damage during radiation therapy. The ideal anti-radiation drug should not affect the sensitivity of tumor cells to radiation therapy while protecting normal cells.

MCE designs a unique collection of 2,457 radioprotectors. Radioprotector Library is an effective tool for acute Radiation Syndrome, drug combination research with radiation drugs.

Cat. No.	Product Name	Type

HY-D1459

BODIPY 665/676	Fluorescent Dyes/Probes
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-129109

NBD-Pen

Fluorescent Dyes/Probes

NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λ_ex: 470 nm, λ_em: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H₂O₂, ClO ^-, O₂ ^-∙, and ∙OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .

HY-130015

HKSOX-1 (5/6-mixture) 2 Publications Verification	Fluorescent Dyes/Probes
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .

HY-130017

HKSOX-1r (5/6-mixture)	Fluorescent Dyes/Probes
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-D0367

Fluorescent Brightener 28 (25% in water)

Calcofluor White M2R

Fluorescent Dyes/Probes

Fluorescent brightener 28 is a fluorescent whitening agent commonly used in the padding process of the textile industry. Fluorescent brightener 28 is capable of staining polysaccharides such as cellulose, and when the plasma membrane ruptures, it also weakly stains the cytoplasm and strongly stains the cell nucleus. Additionally, Fluorescent brightener 28 can be utilized to detect intracellular chitin in living cells. Fluorescent Brightener 28 also is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations .

HY-100512

Benzenepentacarboxylic Acid Pentacarboxybenzene	Fluorescent Dyes/Probes
Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals.

HY-115691

STY-BODIPY Styrene-BODIPY; Styrene-Conjugated BODIPY	Fluorescent Dyes/Probes
STY-BODIPY (Styrene-BODIPY) is a styrene-conjugated fluorogenic probe for measuring radical-trapping antioxidant (RTA) activity .

HY-D0113

7-Hydroxy-4-methyl-2(1H)-quinolone	Fluorescent Dyes/Probes
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .

HY-119987

Sudan orange G SOG	Dyes
Sudan orange G is an azo dye. Sudan orange G, after enzymatic oxidation, generates oligomers and even polymers through free radical coupling reactions .

HY-119987R

Sudan orange G (Standard)	Dyes
Sudan orange G (Standard) is the analytical standard of Sudan orange G. This product is intended for research and analytical applications. Sudan orange G is an azo dye. Sudan orange G, after enzymatic oxidation, generates oligomers and even polymers through free radical coupling reactions .

HY-D1159

HKOH-1r 5+ Cited Publications	Fluorescent Dyes/Probes
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-D1151

HKOH-1 1 Publications Verification	Fluorescent Dyes/Probes
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-130025

HKOCl-3 2 Publications Verification	Fluorescent Dyes/Probes
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.E_x: 490 nm; E_m 527 nm .

HY-D0720

Lucigenin 5+ Cited Publications NSC-151912; L-6868	Fluorescent Dyes/Probes
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O ^2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .

HY-W127725

Thymolphthalexon tetrasodium

Dyes

Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

HY-W011664

1,3-Diphenylisobenzofuran

10+ Cited Publications

DPBF

Fluorescent Dyes/Probes

1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .

HY-D1168

Oil Red O 4 Publications Verification	Fluorescent Dyes/Probes
Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses .

HY-123645

Rhodamine B hydrazide

Fluorescent Dyes/Probes

Rhodamine B hydrazide is a fluorescent derivative based on rhodamine B, containing the spirocyclic structure of Rhodamine B (HY-Y0016), which can be used to detect copper ions (Cu ²⁺), mercury ions, peroxynitrite, hydroxyl radicals and nitric oxide (NO) .
Excitation/emission wavelength:
Conventional detection: 510/578 nm.
Sulfite detection: 554 nm absorption, 574 nm emission (due to the formation of Rhodamine B fluorescent product).

HY-111330

Hydroxyphenyl Fluorescein

3 Publications Verification

HPF; 3'-p-(Hydroxyphenyl) fluorescein

Fluorescent Dyes/Probes

Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .

HY-D1301

BODIPY 581/591 C11

Maximum Cited Publications

61 Publications Verification

Fluorescent Dyes/Probes

BODIPY 581/591 C11 is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype), or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .

HY-D0168

Orcinol

3,5-Dihydroxytoluene

Dyes

Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

Cat. No.	Product Name	Type

HY-N9497

Galactinol	Biochemical Assay Reagents
Galactinol is a biochemical reagent. Galactinol scavenges hydroxyl radicals and protects plant cells from oxidative damage .

HY-W015913

Sodium 2-oxopropanoate 5+ Cited Publications Sodium pyruvate	Cell Assay Reagents
Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W015913R

Sodium 2-oxopropanoate (standard) 4 Publications Verification	Biochemical Assay Reagents
Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W013508

I2959	3D Bioprinting
I2959 is widely used as a photoinitiator for photochemical cross-linking of hydrogels, and the combination of I2959 and CMA hydrogel has been used as a bio-ink for biological 3D printing applications. In addition, I2959 has a high free radical generation efficiency and is cytotoxic to rapidly dividing cell lines .

HY-W002004

4-Amino-TEMPO

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl

Biochemical Assay Reagents

4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-W790758

Tripropylammonium hexafluorophosphate	Cell Assay Reagents
Tripropylammonium hexafluorophosphate is a potent, cell-permeable free radical scavenger suitable for the detection of superoxide radicals and peroxynitrite in vitro.

HY-Y0320C

Dimethyl sulfoxide

DMSO

Co-solvents

Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-D0187

L-Glutathione reduced 30+ Cited Publications GSH; γ-L-Glutamyl-L-cysteinyl-glycine	Cell Assay Reagents Cosmetic Peptides
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-44076

LAP

1 Publications Verification

Lithium phenyl-2,4,6-trimethylbenzoylphosphinate

3D Bioprinting

LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility .

HY-130502

5β,6β-epoxycholestanol Cholesterol 5beta,6beta-epoxide	Drug Delivery
5β,6β-epoxycholestanol is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. Induces lactate dehydrogenase (LDH) release and apoptosis in macrophage-differentiated U937 cells. Cholesterol 5beta,6beta-epoxide has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue .

HY-W616806

Sodium 6-oxo-3,6-dihydropurin-7-ide	Biochemical Assay Reagents
Sodium 6-oxo-3,6-dihydropurin-7-ide, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-Y0319D

Acetic acid lead	Biochemical Assay Reagents
Acetic acid lead can provide either acetate radicals or acetoxonium ions. Acetic acid lead may be an acceptable oxidising agent for the preparation of sulphur (VI) systems, as witnessed by its reaction with thiodithiazyl dichloride .

HY-W776847

3-(2-Iodoacetamido)-proxyl	Biochemical Assay Reagents
3-(2-Iodoacetamido)-proxyl serves as a free radical spin probe employed in spin labeling techniques, which facilitate the exploration of the dynamic interactions among molecules, proteins, lipids, and cell membranes.

HY-D0187R

L-Glutathione reduced (Standard)	Cell Assay Reagents Cosmetic Peptides
L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-172380A

PCL-PEG-PCL diacrylate (PCL average Mn800, PEG average Mn4000)	3D Bioprinting
PCL-PEG-PCL diacrylate (MW 800) is an amphiphilic triblock copolymer composed of PEG and two polycaprolactones (PCL). PCL-PEG-PCL diacrylate (MW 800) can be cross-linked by free radical polymerization and/or photopolymerization to form a cross-linked hydrogel network .

HY-172380

PCL-PEG-PCL diacrylate (PCL Average Mn 200, PEG Average Mn 1000)	3D Bioprinting
PCL-PEG-PCL diacrylate (MW 800) is an amphiphilic triblock copolymer composed of PEG and two polycaprolactones (PCL). PCL-PEG-PCL diacrylate (MW 800) can be cross-linked by free radical polymerization and/or photopolymerization to form a cross-linked hydrogel network .

HY-Y1313

3-Nitrobenzoic acid m-Carboxynitrobenzene; m-Nitrobenzenecarboxylic acid; m-Nitrobenzoic acid	Biochemical Assay Reagents
3-Nitrobenzoic acid (m-Carboxynitrobenzene; m-Nitrobenzenecarboxylic acid; m-Nitrobenzoic acid) is a strong antioxidant and antimicrobial agent that can inhibit the generation of free radicals and kill bacteria and fungi. 3-Nitrobenzoic acid is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W130177

Iodocholine iodide	Biochemical Assay Reagents
Iodocholine iodide is a non-toxic, metabolizable "green" catalyst that can catalyze the free radical polymerization of functional polymers. Iodocholine iodide is also the non-radioactive iodide of Carbon-11 choline. C-11 Choline can be used in PET imaging and non-informative bone scintigraphy, CT or MRI to monitor various types of cancer .

HY-15932

TOOS

TOOS sodium salt

Biochemical Assay Reagents

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

HY-W099538

Dilauryl thiodipropionate

Dilauryl 3,3'-Thiodipropionate

Biochemical Assay Reagents

Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.

HY-Y0320E

Dimethyl sulfoxide (suitable for HPLC)

Co-solvents

Dimethyl sulfoxide (suitable for HPLC) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide (suitable for HPLC) is suitable for HPLC .

HY-134816

D-Glucan

Carbohydrates

D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism) .

HY-W099538R

Dilauryl thiodipropionate (Standard)

Biochemical Assay Reagents

Dilauryl thiodipropionate (Standard) is the analytical standard of Dilauryl thiodipropionate. This product is intended for research and analytical applications. Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.

HY-Y0320GL

Dimethyl sulfoxide (GMP Like)

DMSO (GMP Like)

Co-solvents

Dimethyl sulfoxide (DMSO) (GMP Like) is the GMP Like class Dimethyl sulfoxide (HY-Y0320C). Dimethyl sulfoxide is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .

HY-W011426

Isopropyl palmitate

Propan-2-yl hexadecanoate

Drug Delivery

Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-Y0320

Dimethyl sulfoxide, meets analytical specification of Ch.P.

Maximum Cited Publications

187 Publications Verification

DMSO, meets analytical specification of Ch.P.

Co-solvents

Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-W011426R

Isopropyl palmitate (Standard)

Propan-2-yl hexadecanoate (Standard)

Drug Delivery

Isopropyl palmitate (Standard) is the analytical standard of Isopropyl palmitate. This product is intended for research and analytical applications. Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

Cat. No.	Product Name	Target	Research Area

HY-145779A

H-Glu(Met-OH)-OH TFA	Biochemical Assay Reagents	Metabolic Disease
H-Glu(Met-OH)-OH TFA could induce oxidation of hydroxyl radical .

HY-D0187

L-Glutathione reduced Maximum Cited Publications 34 Publications Verification GSH; γ-L-Glutamyl-L-cysteinyl-glycine	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-P5318

MDYYFEER	Reactive Oxygen Species	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316

MHLWAAK	Peptides	Inflammation/Immunology
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316A

MHLWAAK TFA	Peptides	Inflammation/Immunology
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318A

MDYYFEER TFA	Peptides	Inflammation/Immunology
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317A

MAQAAEYYR TFA	Reactive Oxygen Species	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-145779

H-Glu(Met-OH)-OH	Biochemical Assay Reagents	Metabolic Disease
H-Glu(Met-OH)-OH could induce oxidation of hydroxyl radical .

HY-P4280

Arg-Tyr	Reactive Oxygen Species	Others
Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity .

HY-P1512

Antioxidant peptide A	SOD	Cancer
Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.

HY-P1512A

Antioxidant peptide A TFA	Peptides	Cancer
Antioxidant peptide A TFA is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell .

HY-D0187R

L-Glutathione reduced (Standard)	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-N9413

γ-Glutamyl-S-allylcysteine L-γ-Glutamyl-(S)-Allyl-Cysteine	Peptides	Metabolic Disease
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities .

HY-P4531

H-Ser-Tyr-OH	Opioid Receptor	Neurological Disease
H-Ser-Tyr-OH is a dipeptide consisting of glutamic acid, glycine and histidine. H-Ser-Tyr-OH can form a copper(II) complex with copper ions to form a strong free radical scavenging activity. H-Ser-Tyr-OH also increases the intracellular uptake of the delta opioid receptor ligand deltorphin .

HY-W013494

L-Carnosine 2 Publications Verification	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging .

HY-W001158

N,N-Dimethylglycine hydrochloride 1 Publications Verification Dimethylglycine hydrochloride; DMG hydrochloride; N-Methylsarcosine hydrochloride	Endogenous Metabolite iGluR Amino Acid Derivatives	Neurological Disease Metabolic Disease
N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Fungal Bacterial IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-W013494R

L-Carnosine (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging . L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability .

Cat. No.	Product Name	Target	Research Area

HY-P99731

Milatuzumab 2 Publications Verification hLL1; MEDI-115	CD74	Cancer
Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N4177

Rubrofusarin gentiobioside	Seeds of Cassia tora Linn. Structural Classification Monophenols other families Classification of Application Fields Leguminosae Source classification Phenols Metabolic Disease Plants Disease Research Fields	Others
Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect .

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Structural Classification Source classification Dendranthema morifolium (Ramat.) Tzvel. Phenols Polyphenols Plants Compositae	Others
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-N9095

Curculigoside C	Curculigo orchioides Gaertn. Structural Classification Source classification Phenols Polyphenols Plants Amaryllidaceae	Others
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N8274

Flavidin	Structural Classification Monophenols Orchidaceae Source classification Coelogyne longipes Lindl. Phenols Plants	Others
Flavidin, an aromatic compound, can be isolated from Coelogyne longipe. Flavidin is an antioxidant, and has radical scavenging activity .

HY-N9289

Vitedoin A	Structural Classification Verbenaceae Source classification Lignans Phenylpropanoids Plants Vitex negundo Linn.	Others
Vitedoin A is a phenyldihydronaphthalene-type lignan. Vitedoin A has antioxidative activity and radical-scavenging effect. Vitedoin A can be isolated from Vitex negundo .

HY-N8579

Eugenyl benzoate	Structural Classification Microorganisms Simple Phenylpropanols Source classification Phenylpropanoids	Others
Eugenyl benzoate has the potency for scavenging of DPPH radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors .

HY-N0499A

Cyanidin	Structural Classification Caprifoliaceae Source classification Phenols Polyphenols Sambucus williamsii Hance Plants	Others
Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity .

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Quinones Structural Classification Anthraquinones Polygonaceae Source classification Rheum rhabarbarum Linnaeus Plants	Others
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

HY-N10985

Xanthone V1a	Structural Classification Flavonoids Maclura fruticosa (Roxburgh) Corner Source classification Plants Moraceae Other Flavonoids	Others
Xanthone V1a has antioxidant activity against the DPPH radical (IC₅₀: 10.43 µM). Xanthone V1a has cytotoxicity against cancer cells .

HY-111523

Isomahanine	Alkaloids Structural Classification Rutaceae Murraya koenigii (L.) Spreng Plants Indole Alkaloids	p38 MAPK Apoptosis Autophagy Caspase
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

HY-N9068

Alterlactone	Structural Classification Natural Products Microorganisms Source classification	Fungal
Alterlactone is an antimicrobial. Alterlactone shows broad antimicrobial activity against bacterial and fungal. Alterlactone has strong radical scavenging activity .

HY-N3596

Cleomiscosin C Aquillochin	Structural Classification Thymelaeaceae Source classification Phenols Polyphenols Plants Aquilaria sinensis (Lour.) Spreng.	Others
Cleomiscosin C (Aquillochin) can be isolated from Aquilaria agallocha. Cleomiscosin C has antioxidant activity. Cleomiscosin C inhibits LDL oxidation and free radicals generation .

HY-N7518

Eulophiol	Classification of Application Fields Pholidota yunnanensis Rolfe Orchidaceae Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

HY-N1859

3'-O-Methylorobol	Structural Classification Flavonoids Alhagi maurorum var. sparsifolium (Shap.) Yakovlev/Alhagi sparsifolia Shap. Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones	Others
3'-O-Methylorobol, an antioxidant flavonoid, exhibits moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay .

HY-N4168B

Methyl chlorogenate	Structural Classification Crataegus monogyna Jacq. Source classification Rosaceae Phenols Polyphenols Plants	Others
Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis .

HY-N8042

Erigeside I	Structural Classification Source classification Phenols Polyphenols Plants Compositae Erigeron breviscapus (Vant.) Hand.-Mazz. Saccharides Monosaccharides	Others
Erigeside I is a free radical scavenger isolated from Erigeron breviscapus .

HY-N10020

Patulitrin	Structural Classification Flavonols Flavonoids Ohwia caudata (Thunberg) H. Ohashi Source classification Plants Compositae	Lipoxygenase
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-114651

Phenazoviridin	Structural Classification Microorganisms Source classification Saccharides Monosaccharides	Others
Phenazoviridin is a free radical scavenger. Phenazoviridin shows strong inhibitory activity against lipid peroxidation in rat brain homogenate and exhibits antihypoxic activity in mice .

HY-W021267

3-Demethylcolchicine	Alkaloids Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields Inflammation/Immunology	Reactive Oxygen Species
3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema .

HY-N9447

Norbergenin 1 Publications Verification	Structural Classification Natural Products other families Source classification Phenols Polyphenols Plants	Reactive Oxygen Species
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-N10770

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone	Structural Classification Flavonoids Gramineae Source classification Plants Other Flavonoids Saccharum officinarum	Others
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .

HY-N9051

6-Prenylquercetin-3-Me ether	Structural Classification Flavonoids Flavones Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Glycosidase
6-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase .

HY-W015913

Sodium 2-oxopropanoate 5+ Cited Publications Sodium pyruvate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Reactive Oxygen Species Endogenous Metabolite
Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Flavonols Flavonoids Source classification Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae	Others
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-W020183

γ-Terpinene	Structural Classification Other Monoterpenes other families Terpenoids Source classification Plants	Fungal Bacterial
γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-N3985

Gyrophoric acid	Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields Cancer	Others
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows *DPPH radical* scavenging** activity with an IC₅₀ value of 105.75 μg/ml .

HY-N8844

2''-O-Galloylquercitrin	Source classification Sapindaceae Acer tataricum subsp. ginnala (Maximowicz) Wesmael Plants	Others
2"-O-Galloylquercitrin (Compound 6) is isolated from the natural Acer ginnala. 2"-O-Galloylquercitrin has health benefits. 2"-O-Galloylquercitrin has the activity of free radical scavenger .

HY-N3847

Eriodictyol-7-O-glucoside Eriodictyol 7-O-β-D-glucoside	Flavonoids Classification of Application Fields Labiatae Flavonones Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Petalostemun purpureum	Keap1-Nrf2
Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity .

HY-125568

Pyridoxatin	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Pyridine Alkaloids Disease Research Fields	MMP
Pyridoxatin is a free radical scavenger of microbial origin. Pyridoxatin is isolated from a fungus culture identified as Acremonium sp. BX86. Pyridoxatin inhibits lipid peroxidation induced by free radicals in rat liver microsomes free from vitamin E .

HY-N15440

Mutatochrome Citroxanthin	Structural Classification Natural Products Source classification Rosaceae Plants Rosa foetida Herrm.	Reactive Oxygen Species Endogenous Metabolite
Mutatochrome (Citroxanthin) is a naturally occurring carotenoid pigment found in certain plants. Mutatochrome has antioxidant property to help protect cells from damage caused by free radicals. Mutatochrome can be used for anti-inflammatory and anticancer study .

HY-N7692

Polyporusterone A	Classification of Application Fields Source classification Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids	Others
Polyporusterone A is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone A has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N10176

D-Isofloridoside	Cardiovascular Disease other families Classification of Application Fields Source classification Plants Disease Research Fields Saccharides	Reactive Oxygen Species MMP
D-Isofloridoside, one of the polysaccharide precursors, has the activity of scavenging free radicals, inhibiting ROS expression, and inhibiting MMP-2 and MMP-9 .

HY-N7693

Polyporusterone B	Classification of Application Fields Source classification Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids	Others
Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N10294

Epicoccone B	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Disease Research Fields Inflammation/Immunology	HIV
Epicoccone B, firstly reported from C. globosum, exhibits the DPPH free radical scavenging ability with IC₅₀ value of 10.8 μM, and has potent α-glucosidase inhibition with IC₅₀ value of 27.3 μM. Anti-HIV activity .

HY-W021267R

3-Demethylcolchicine (Standard)	Alkaloids Structural Classification Monophenols other families Other Alkaloids Source classification Phenols Plants	Reactive Oxygen Species
3-Demethylcolchicine (Standard) is the analytical standard of 3-Demethylcolchicine. This product is intended for research and analytical applications. 3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema .

HY-N3220

Myricetin 3-O-galactoside 1 Publications Verification	Flavonols Structural Classification Flavonoids Rhododendron dauricum Linn. Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Ericaceae Plants Disease Research Fields	Xanthine Oxidase
Myricetin 3-O-galactoside inhibits xanthine oxidase (XO) activity, lipid peroxidation and scavenges the free radical. Myricetin 3-O-galactoside inhibits lipid peroxidation with an IC₅₀ of 160 μg/mL. Antioxidant activity .

HY-N2307A

Lirinidine (+)-Lirinidine	Alkaloids Monophenols Classification of Application Fields Source classification Phenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Disease Research Fields Nymphaeaceae Cancer	Others
Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research .

HY-W015913R

Sodium 2-oxopropanoate (standard) 4 Publications Verification	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reactive Oxygen Species Endogenous Metabolite
Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W020183R

γ-Terpinene (Standard)	Structural Classification Other Monoterpenes other families Terpenoids Source classification Plants	Fungal Bacterial
γ-Terpinene (Standard) is the analytical standard of γ-Terpinene. This product is intended for research and analytical applications. γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-W001542

5-Hydroxyoxindole	Structural Classification Neurological Disease Classification of Application Fields Source classification Haldina cordifolia (Roxb.) Ridsd. Metabolic Disease Plants Indole Alkaloids Alkaloids Monophenols Rubiaceae Phenols Disease Research Fields	Reactive Oxygen Species
5-Hydroxyoxindole is a structural analog of uric acid. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-N3554

Catechin-7-O-β-D-xylopyranoside (+)-Catechol 7-β-D-xylopyranoside	Structural Classification Betula pendula Roth. Source classification Plants Saccharides Betulaceae Monosaccharides	Others
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .

HY-N3315

Massonianoside B	Structural Classification Cedrus deodara (Roxburgh) G. Don Monophenols Pinaceae Source classification Phenols Plants	Others
Massonianoside B is an antioxidant, which can be isolated from Cedrus deodara pine needle. Massonianoside B exhibits radicals scavenging capacities, and restores CCL4-impaired activity of antioxidant enzymes .

HY-N10927

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene	Structural Classification Terpenoids Labiatae Source classification Cassia Diterpenoids Plants	Others
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC₅₀ value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity .

HY-N13142

Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside	Structural Classification Flavonoids Margaritopsis carrascoana Flavones Source classification Rubiaceae Plants	Others
Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside (compound 3) is a flavonoid with antioxidant activity, which can be isolated from Margaritopsis carrascoana. Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside has good DPPH free radical scavenging activity (IC50=0.188 mg/mL) .

HY-N3138

Ombuoside	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Cucurbitaceae Phenols Polyphenols Plants Gynostemma pentaphyllum (Thunb.) Makino Disease Research Fields	Bacterial
Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.Ombuoside has antimicrobial activity against several strains of gram-positive and gram-negative bacteria and the yeast Candida albicans . Ombuoside has antioxidant effects by scavenging free radicals and ROS .

HY-116866

Sclerotiorin	Structural Classification Natural Products Microorganisms Source classification	Lipoxygenase Fungal
Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC₅₀: 4.2 μM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED₅₀: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans .

HY-111898

Epirosmanol	Source classification Plants	Others
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .

HY-N3451

Isothymusin	Structural Classification Flavonoids Classification of Application Fields Flavones Labiatae Source classification Balsamorhiza macrophylla Nutt. Plants Disease Research Fields Cancer	Lipoxygenase
Isothymusin is a potent anti-oxidant agent. Isothymusin shows radical scavenging activities. Isothymusin shows anti-proliferative activities in cancer cell lines. Isothymusin inhibited the enzymes associated with the promotion stage of cancer, including cycloxygenase- 2 and lipoxygenase-5 .

HY-34350

2-(Aminomethyl)phenol 2-Hydroxybenzylamine; o-Hydroxybenzylamine; 2-HOBA	Cardiovascular Disease Structural Classification Monophenols Reseda odorata L. Oleaceae Classification of Application Fields Phenols Plants Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
2-(Aminomethyl)phenol (2-Hydroxybenzylamine), a selective dicarbonyl scavenger, is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). 2-(Aminomethyl)phenol can be used in the research of inflammation and cardiovascular disease, such as atherosclerosis, early recurrence of atrial fibrillation (AF) and arrhythmias .

HY-N11845

Sigmoidin B	Structural Classification Flavonoids Flavones Leguminosae Source classification Plants Erythrina latissima E. Mey.	Lipoxygenase
Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotoxic activity that inhibits genotoxicity induced by Aflatoxin B1 (HY-N6615), with an IC₅₀ of 18.7 μg/mL. Sigmoidin B has anti-inflammatory activity and antioxidant properties .

Cat. No.	Product Name	Chemical Structure

HY-N0091S5

Hypoxanthine-d4
Hypoxanthine-d₄ is the deuterium labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-N0091S6

Hypoxanthine-d2
Hypoxanthine-d₂ is the deuterium labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-N0091S7

Hypoxanthine-15N4 1 Publications Verification
Hypoxanthine- ¹⁵N₄ is the ¹⁵N labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-N0091S2

Hypoxanthine-13C5
Hypoxanthine- ¹³C₅ is a ¹³C-labeled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-42682S1

D(+)-Galactosamine-13C hydrochloride
D(+)-Galactosamine- ¹³C (hydrochloride) is the ¹³C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and

HY-113248S

3-Nitro-L-tyrosine-d3
3-Nitro-L-tyrosine-d₃ is the deuterium labeled 3-Nitro-L-tyrosine. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions .

HY-D0187S

L-Glutathione reduced-13C2,15N
L-Glutathione reduced- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-W654342

Spermine-d20
Spermine-d₂₀ (NSC 268508-d₂₀) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects .

HY-N0683S6

α-Vitamin E-d11
α-Vitamin E-d11 ((+)-α-Tocopherol-d11) is the deuterium labeled α-Vitamin E (HY-N0683). α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-34439S1

2,5-Dimethylpyrazine-d3
2,5-Dimethylpyrazine-d₃ is deuterated labeled 2,5-Dimethylpyrazine (HY-34439). 2,5-Dimethylpyrazine is an endogenous metabolite.

HY-B0099S

Edaravone-d5
Edaravone-d₅ is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator .

HY-113248S1

3-Nitro-L-tyrosine-13C6
3-Nitro-L-tyrosine- ¹³C₆ is the ¹³C labeled 3-Nitro-L-tyrosine . 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions .

HY-N0091S1

Hypoxanthine-13C,15N2
Hypoxanthine- ¹³C, ¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-N0091S3

Hypoxanthine-13C2,15N
Hypoxanthine- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-113121S1

Vanillylmandelic acid-d1
Vanillylmandelic acid-d is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC₅₀ value of 33 μM .

HY-N0091S

Hypoxanthine-13C5,15N4
Hypoxanthine- ¹³C₅, ¹⁵N4 is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-B1978S

Iprodione-d5
Iprodione-d₅ is the deuterium labeled Iprodione . Iprodione, a dicarboximide fungicide, has a highly specific action, with a capacity to cause oxidative damage through production of free oxygen radicals (ROS). Iprodione does not appear to be species selective .

HY-N0091S4

Hypoxanthine-13C2,15N-1
Hypoxanthine- ¹³C₂, ¹⁵N-1 is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-113121S

Vanillylmandelic acid-d3
Vanillylmandelic acid-d₃ is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC₅₀ value of 33 μM .

HY-D0187S4

L-Glutathione reduced-13C
L-Glutathione reduced- ¹³C (GSH- ¹³C; γ-L-Glutamyl-L-cysteinyl-glycine- ¹³C) is ¹³C-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-W015913S3

Sodium 2-oxopropanoate-13C
Sodium 2-oxopropanoate- ¹³C is the ¹³C labeled Sodium 2-oxopropanoate . Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W015913S1

Sodium 2-oxopropanoate-d3
Sodium 2-oxopropanoate-d₃ is the deuterium labeled Sodium 2-oxopropanoate . Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W015913S

Sodium 2-oxopropanoate-13C3
Sodium 2-oxopropanoate- ¹³C₃ is the ¹³C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-D0187S5

L-Glutathione reduced-d2
L-Glutathione reduced-d₂ (GSH-d₂; γ-L-Glutamyl-L-cysteinyl-glycine-d₂) is deuterated-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-W015913S4

2-Oxopropanoate-13c2 sodium
2-Oxopropanoate- ¹³C₅ (sodium) is the ¹³C labeled Sodium 2-oxopropanoate . Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-B2130S1

Uric acid-15N2
Uric acid- ¹⁵N₂ is the ¹⁵N labeled Uric acid . Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-D0187S6

L-Glutathione reduced-15N
L-Glutathione reduced- ¹⁵N (GSH- ¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine- ¹⁵N) is ¹⁵N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.

HY-N0136S

Taxifolin-d3
Taxifolin-d₃ is deuterium labeled Taxifolin. Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-W001187S

Tempo-d18
Tempo-d₁₈ is the deuterium labeled Tempo . Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects .

HY-N0523S

Gallic acid-d2
Gallic acid-d₂ is the deuterium labeled Gallic acid . Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .

HY-W003972S1

2,6-Dimethoxyphenol-d6
2,6-Dimethoxyphenol-d₆ (Syringol-d₆) is deuterated labeled 2,6-Dimethoxyphenol (HY-W003972). 2,6-Dimethoxyphenol is a phenolic compound that scavenges free radicals and exhibits antioxidant activity. 2,6-Dimethoxyphenol is the substrate for determining laccase activity .

HY-B2130S

Uric acid-13C,15N3
Uric acid- ¹³C, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-W003972S

2,6-Dimethoxyphenol-d3
2,6-Dimethoxyphenol-d₃ (Syringol-d₃) is the deuterium labeled 2,6-Dimethoxyphenol (HY-W003972) . 2,6-Dimethoxyphenol is a phenolic compound that scavenges free radicals and exhibits antioxidant activity. 2,6-Dimethoxyphenol is the substrate for determining laccase activity .

HY-W002004S1

4-Amino-TEMPO-d17

4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-W020183S

γ-Terpinene-d3
γ-Terpinene-d₃ is deuterated labeled γ-Terpinene (HY-W020183). γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-B0817S

Pyridaben-d13

Pyridaben-d₁₃ is the deuterium labeled Pyridaben . Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

HY-W002004S

4-Amino-TEMPO-d17,15N

4-Amino-TEMPO-d₁₇, ¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇, ¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-N0136S1

(±)-Taxifolin-13C3

(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-B1899S

Taurodeoxycholic acid-d5

Taurodeoxycholic acid-d₅ is the deuterium labeled Taurodeoxycholic acid (HY-B1899) . Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD) .

HY-W758421

Diquat-d8 dibromide

Diquat-d₈ dibromide is a deuterium labeled Diquat dibromide (HY-122984). Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .

HY-W001158S1

N,N-Dimethylglycine-d3 hydrochloride

N,N-Dimethylglycine-d₃ (Dimethylglycine-d₃) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects .

HY-128463S

N-tert-Butyl-α-phenylnitrone-d14

N-tert-Butyl-α-phenylnitrone-d₁₄ is the deuterium labeled N-tert-Butyl-α-phenylnitrone . N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .

HY-W001158S

N,N-Dimethylglycine-d6 hydrochloride

N,N-Dimethylglycine-d₆ (Dimethylglycine-d₆) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects .

HY-N6937S1

(R,R)-Secoisolariciresinol diglucoside-d6

(R,R)-Secoisolariciresinol diglucoside-d₆ is deuterated labeled (R,R)-Secoisolariciresinol diglucoside (HY-N6937). (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .

Cat. No.	Product Name		Classification

HY-131036

MAO-IN-M30 dihydrochloride		Alkynes
MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC₅₀=37 nM) and MAO-B (IC₅₀=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease . MAO-IN-M30 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-131803

3'-Azido-3'-deoxyguanosine		Azide
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-N0523A

Gallic acid hydrate 10+ Cited Publications 3,4,5-Trihydroxybenzoic acid hydrate		Antioxidants Chelating Agents Preservatives
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .

HY-W011426

Isopropyl palmitate Propan-2-yl hexadecanoate		Solvents
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-Y0320

Dimethyl sulfoxide, meets analytical specification of Ch.P. 185+ Cited Publications DMSO, meets analytical specification of Ch.P.		Solvents
Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

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