Phenazine methylsulfate (Standard)  (Synonyms: 5-Methylphenazinium methylsulfate (Standard))

Phenazine (methylsulfate) (Standard) is the analytical standard of Phenazine (methylsulfate). This product is intended for research and analytical applications. Phenazine methylsulfate is a free radical generator that can act as an electron transfer reactant in cell viability assays. It also has insecticidal properties. Furthermore, Phenazine methylsulfate induces oxidative DNA damage and cell apoptosis, showing antitumor activity[1][2][3].

306.34

C₁₄H₁₄N₂O₄S

299-11-6

C[N+]1=C2C=CC=CC2=NC3=C1C=CC=C3.O=S(OC)([O-])=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. G E Edwards, et al. Action of phenazine methyl sulfate, inhibitors, and uncouplers on the light-induced proton transport by cells ofRhodospirillum rubrum. J Membr Biol. 1970 Dec;2(1):95-107.  [Content Brief]

  [2]. Anh B Hua, et al. Repurposing the Electron Transfer Reactant Phenazine Methosulfate (PMS) for the Apoptotic Elimination of Malignant Melanoma Cells through Induction of Lethal Oxidative and Mitochondriotoxic Stress. Cancers (Basel). 2019 Apr 27;11(5):590.  [Content Brief]

  [3]. E Pontiki, et al. Evaluation of anti-inflammatory and antioxidant activities of copper (II) Schiff mono-base and copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole. J Enzyme Inhib Med Chem. 2008 Dec;23(6):1011-7.  [Content Brief]