2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 2-Bromo-4'-fluoroacetophenone

2-Bromo-4'-fluoroacetophenone  (Synonyms: p-Fluorophenacyl bromide)

Cat. No.: HY-W008598 Purity: 98.0%
COA
SDS
Handling Instructions Technical Support

2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.

For research use only. We do not sell to patients.

2-Bromo-4'-fluoroacetophenone

2-Bromo-4'-fluoroacetophenone Chemical Structure

CAS No. : 403-29-2

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Based on 1 publication(s) in Google Scholar

Other Forms of 2-Bromo-4'-fluoroacetophenone:

2-Bromo-4'-fluoroacetophenone Related Antibodies

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Description

2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.

Molecular Weight

217.04

Formula

C8H6BrFO
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

BrCC(C1=CC=C(F)C=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 66.67 mg/mL (307.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6074 mL 23.0372 mL 46.0745 mL
5 mM 0.9215 mL 4.6074 mL 9.2149 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.14%

COA (245 KB) HNMR (111 KB) GC (112 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.6074 mL 23.0372 mL 46.0745 mL 115.1861 mL
5 mM 0.9215 mL 4.6074 mL 9.2149 mL 23.0372 mL
10 mM 0.4607 mL 2.3037 mL 4.6074 mL 11.5186 mL
15 mM 0.3072 mL 1.5358 mL 3.0716 mL 7.6791 mL
20 mM 0.2304 mL 1.1519 mL 2.3037 mL 5.7593 mL
25 mM 0.1843 mL 0.9215 mL 1.8430 mL 4.6074 mL
30 mM 0.1536 mL 0.7679 mL 1.5358 mL 3.8395 mL
40 mM 0.1152 mL 0.5759 mL 1.1519 mL 2.8797 mL
50 mM 0.0921 mL 0.4607 mL 0.9215 mL 2.3037 mL
60 mM 0.0768 mL 0.3840 mL 0.7679 mL 1.9198 mL
80 mM 0.0576 mL 0.2880 mL 0.5759 mL 1.4398 mL
100 mM 0.0461 mL 0.2304 mL 0.4607 mL 1.1519 mL
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2-Bromo-4'-fluoroacetophenone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Bromo-4'-fluoroacetophenone403-29-2p-FluorophenacylDNA/RNA SynthesisInhibitorinhibitorinhibit

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