2. Others Protein Tyrosine Kinase/RTK Metabolic Enzyme/Protease Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor PI3K/Akt/mTOR Epigenetics
  3. Reference Standards Ephrin Receptor PPAR AMPK
  4. Urolithin D (Standard)

Urolithin D (Standard)  (Synonyms: 3,4,8,9-Tetrahydroxy urolithin (Standard))

Cat. No.: HY-133178R Purity: ≥98%
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Urolithin D (Standard) (3,4,8,9-Tetrahydroxy urolithin (Standard)) is the analytical standard of Urolithin D (HY-133178). This product is intended for research and analytical applications. Urolithin D (3,4,8,9-Tetrahydroxy urolithin) is a colonic metabolite of Ellagitannins and a competitive, reversible, and selective antagonist of the EphA receptor. Urolithin D inhibits EphA2-ephrin-A1 binding with an IC50 of 0.9 μM. Urolithin D is also a potent antioxidant that scavenges free radicals and repairs oxidized DNA damage. Additionally, Urolithin D suppresses triglyceride accumulation and promotes fatty acid oxidation by activating the AMPK signaling pathway. Urolithin D can be used for research on tumors, metabolic, and inflammatory diseases.

For research use only. We do not sell to patients.

Urolithin D (Standard) Chemical Structure

Urolithin D (Standard) Chemical Structure

CAS No. : 131086-98-1

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Description

Urolithin D (Standard) (3,4,8,9-Tetrahydroxy urolithin (Standard)) is the analytical standard of Urolithin D (HY-133178). This product is intended for research and analytical applications. Urolithin D (3,4,8,9-Tetrahydroxy urolithin) is a colonic metabolite of Ellagitannins and a competitive, reversible, and selective antagonist of the EphA receptor. Urolithin D inhibits EphA2-ephrin-A1 binding with an IC50 of 0.9 μM. Urolithin D is also a potent antioxidant that scavenges free radicals and repairs oxidized DNA damage. Additionally, Urolithin D suppresses triglyceride accumulation and promotes fatty acid oxidation by activating the AMPK signaling pathway. Urolithin D can be used for research on tumors, metabolic, and inflammatory diseases.

Molecular Weight

260.20

Formula

C13H8O6
CAS No.
SMILES

O=C1C2=CC(O)=C(O)C=C2C3=CC=C(O)C(O)=C3O1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Urolithin D (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Urolithin D (Standard)131086-98-13,4,8,9-Tetrahydroxy urolithin (Standard)Reference StandardsEphrin ReceptorPPARAMPKPeroxisome proliferator-activated receptorsAMP-activated protein kinaseInhibitorinhibitorinhibit

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