Search Result

Results for "

MHC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MHC (43) Amino Acid Derivatives (2) Apoptosis (2) Arenavirus (2) Bacterial (2) Biochemical Assay Reagents (1) CD28 (1) CD3 (1) CD74 (1) DNA Methyltransferase (1) Dopamine Receptor (1) Drug Metabolite (1) EGFR (1) Endogenous Metabolite (3) FAK (1) Fc Receptor (FcR) (1) G protein-coupled Bile Acid Receptor 1 (2) Glucocorticoid Receptor (1) HBV (1) HIV (2) IFNAR (2) iGluR (1) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (2) JAK (2) LAG-3 (7) MDM-2/p53 (1) mRNA (1) PD-1/PD-L1 (1) Phosphatase (1) Phosphodiesterase (PDE) (2) PROTACs (4) Proteasome (1) Reactive Oxygen Species (ROS) (1) RNA MTase (1) RSV (1) Small Interfering RNA (siRNA) (1) STING (1) TNF Receptor (3) Transmembrane Glycoprotein (4) Tyrosinase (1) Wnt (4) β-catenin (2)
By Research Areas:	Cancer (41) Cardiovascular Disease (1) Endocrinology (1) Infection (8) Inflammation/Immunology (56) Metabolic Disease (4) Neurological Disease (3)
Oligonucleotides:	mRNA (1) Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

113

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: MHC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990832

*Anti-MHC* Class I Antibody (W6/32)**	MHC	Inflammation/Immunology
Anti-MHC Class I Antibody (W6/32) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human MHC Class I. Anti-MHC Class I Antibody (W6/32) reacts with the human major histocompatibility complex (MHC) class I, HLA-A, B, and C. Anti-MHC Class I Antibody (W6/32) increases adherence of monocytes to human endothelial cells. Anti-MHC Class I Antibody (W6/32) can be used for the research of immunology .

HY-P99135

*Anti-Mouse MHC* Class I (H-2Kb) Antibody (Y-3)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) is a mouse-derived IgG2b antibody inhibitor, targeting to mouse MHC Class I (H-2Kb). Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) reacts with the mouse H-2Kb, H-2Kk, H-2Kq, H-2Kr, H-2ks MHC class I alloantigens and not H-2Kd. Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) can block MHC Class I. Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) can be used for immunology research .

HY-P990195

*Anti-Mouse MHC* Class I (H-2) Antibody (M1/42.3.9.8)**	MHC	Others
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) reacts with the mouse H-2 MHC class I alloantigen (all haplotypes). Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) can be used for the flow cytometry and immunofluorescence experiments .

HY-157997

MHC02181	Phosphodiesterase (PDE)	Cancer
MHC02181 is a potent inhibitor of Autotaxin (ATX), with IC₅₀ of 9.41 μM .

HY-158001

MHC00188	Phosphodiesterase (PDE)	Others Cancer
MHC00188 is an allosteric inhibitor for Autotaxin (ATX) with an IC₅₀ of 2.53 μM .

HY-P990192

*Anti-Mouse MHC* Class I (H-2Kk) Antibody (AF3-12.1.3)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) reacts with the mouse H-2Kk MHC class I alloantigen. Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) can be used for the researches of inflammation and immunology, such as obliterative airway disease .

HY-P990194

*Anti-Mouse MHC* Class I (H-2Kd) Antibody (HB-159)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159) reacts with the mouse H-2Kd MHC class I alloantigen. Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159) can be used for immunology research, such as cardiac graft .

HY-P990190

*Anti-Swine MHC* Class I (SLAd) Antibody (74-11-10)**	MHC	Others
Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to *Swine MHC* Class I*. Anti-Swine MHC* Class I (SLAd) Antibody (74-11-10) reacts with the swine leucocyte antigen (SLA) class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) can be used for the research of flow cytometry experiments .

HY-P990184

*Anti-Mouse MHC* Class II (βchain) Antibody (KL277)**	MHC	Others
Anti-Mouse MHC Class II (βchain) Antibody (KL277) is a hamster/mouse-derived IgG type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (βchain) Antibody (KL277) reacts with mouse MHC Class II haplotypes I-Ab, I-Ad, I-Ap, I-Aq, I-Abu, and I-Abw. Anti-Mouse MHC Class II (βchain) Antibody (KL277) does not react with I-Aa, I-Ak, I-Af, I-Aj, I-As, or I-Atl haplotypes. Anti-Mouse MHC Class II (βchain) Antibody (KL277) can be used for western blot experiments .

HY-P990188

*Anti-Mouse MHC* class II (I-A) Antibody (Y-3P)**	MHC	Inflammation/Immunology
Anti-Mouse MHC class II (I-A) Antibody (Y-3P) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC class II. Anti-Mouse MHC class II (I-A) Antibody (Y-3P) reacts with mouse MHC Class II haplotypes I-Ab, I-Af, I-Ap, I-Aq, I-Ar, I-As, I-Au, I-Av, and weakly with I-Ak. Anti-Mouse MHC class II (I-A) Antibody (Y-3P) blocks MHC class II and inhibits expansion of regulate T cells. Anti-Mouse MHC class II (I-A) Antibody (Y-3P) can be used for the immunology research .

HY-P990185

*Anti-Mouse/Rat MHC* Class II (I-Ek/RT1-D) Antibody (14-4-4S)**	MHC	Inflammation/Immunology Cancer
Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/rat MHC Class II. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) reacts with mouse MHC Class II alloantigen I-Ek and the rat MHC class II alloantigen RT1D. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) blocks antigen presentation. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) can be used for the research of immunology and cancer .

HY-P990187

*Anti-Mouse MHC* Class II (I-A/I-E) Antibody (M5/114)**	MHC Influenza Virus	Infection Inflammation/Immunology
Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) reacts with mouse MHC Class II haplotypes I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) does not react with I-Af, I-Ak, or I-As haplotypes. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) blocks MHC Class II and inhibit T cell generation. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) can be used for the researches of infection and immunology, such as influenza A virus (IAV) infection .

HY-P990189

*Anti-Monkey/Human MHC* class II (HLA-DR) Antibody (L243)**	MHC Apoptosis Reactive Oxygen Species (ROS)	Infection Cancer
Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to monkey/human MHC class II. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can inhibits tumor cells proliferation and induce apoptosis. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) increases cellular reactive oxygen species (ROS) and loss of mitochondrial membrane potential in human endothelial cells. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can be used for the researches of cancer and infection, such as lymphoma .

HY-P990813

*Anti-Mouse Nonclassical MHC* Class I molecule Qa-1b Antibody (4C2.4A7.5H11)**	MHC	Cancer
Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11) is a mouse-derived IgG1 antibody inhibito, targeting to mouse *Nonclassical MHC* Class I molecule Qa-1b*. Anti-Mouse Nonclassical MHC* Class I molecule Qa-1b Antibody (4C2.4A7.5H11) reacts with the mouse non-classical MHC class I molecule Qa-1b. Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11) can be used for the research of cancer, such as B16F10 tumor .

HY-P990191

*Anti-Mouse MHC* Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13))**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) reacts with the mouse H-2Kk and H-2Dk MHC class I alloantigens. Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) can be used for immunology research .

HY-P990186

*Anti-Mouse MHC* Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2)**	MHC	Others
Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) is a mouse-derived IgG2c κ type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) reacts with mouse MHC Class II haplotypes I-Ak, I-Ar, I-Af, I-As, and I-Ag7. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) does not react with I-Ab, I-Ad, I-Ap, or I-Aq haplotypes. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) blocks MHC Class II and inhibits antigen proliferation responses. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) can be used for the research of immunology .

HY-157277

AdBeSA	Others	Cancer
AdBeSA is a hapten. AdBeSA can influence peptide binding by MHC II .

HY-P990193

*Anti-Mouse MHC* Class I (H-2Kd, H-2Dd) Antibody (34-1-2S)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) is an anti-mouse MHC Class I (H-2Kd, H-2Dd) IgG2a monoclonal antibody. Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) can block the interaction between Ly49 and MHC-I. Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) can be used for the construction of acute lung injury models .

HY-157171

Ac-YR-NH2	MHC	Inflammation/Immunology
Ac-YR-NH2 is a small molecule modulator of MHC class II antigen presentation. Ac-YR-NH2 can influence peptide binding by MHC II to influence immune response .

HY-P3715

OVA peptide 2 Publications Verification	MHC	Inflammation/Immunology
OVA peptide mainly exists in egg white, it is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA peptide has been widely studied in allergy research .

HY-P990244

Anti-Rat FcRn heavy chain heterodimers Antibody (2G3)	Fc Receptor (FcR)	Inflammation/Immunology
Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is an anti-rat FcRn heavy chain heterodimers IgG1 monoclonal antibody. Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) effectively inhibits the binding of FcRn to IgG. Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is used in studies of the MHC class I heavy chain FcRn heterodimers and their interaction with IgG .

HY-P5745

TYVPANASL	Transmembrane Glycoprotein	Cancer
TYVPANASL is a MHC I-binding CD8 T cell epitope of nine amino acids from HER2/neu. TYVPANASL can be used to prepare J-LEAPS vaccine .

HY-P5745A

TYVPANASL TFA	MHC EGFR	Cancer
TYVPANASL TFA is a MHC I-binding CD8 T cell epitope of nine amino acids from HER2/neu. TYVPANASL TFA can be used to prepare J-LEAPS vaccine .

HY-P6312

ESAT6 Epitope	Bacterial	Infection
ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC₅₀=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity .

HY-P2527

Tyrosinase-related Protein 2 (TRP-2) (181-188)	Tyrosinase	Inflammation/Immunology
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a tyrosinase-related protein 2 (TRP-2)-derived peptide, corresponding to residues 180-188. Tyrosinase-related Protein 2 (TRP-2) (181-188) is the major reactive epitope within TRP-2 recognized by anti-B16 CTLs. Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide conforming to the MHC class I H2-Kb binding motif .

HY-157269

J10-1	Others	Inflammation/Immunology
J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB10401)) and promotes peptide binding to MHC* II, which can be used in the study of immune regulation .

HY-P99129

Anti-Mouse CD8a Antibody (53-6.7) 2 Publications Verification	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD8a Antibody (53-6.7) is an anti-mouse CD8a IgG2a antibody inhibitor derived from host Rat. Anti-Mouse CD8a Antibody (53-6.7) binds to CD8αβ stabilizes a conformation with a higher affinity for interaction with MHC class I. Anti-Mouse CD8a Antibody (53-6.7) induces the phosphorylation and activation of TCR proximal signaling pathway components Lck and ZAP70 in polyclonal memory T cells. Anti-Mouse CD8a Antibody (53-6.7) depletes CD8+ T cells and neutralizes cytokine in mice .

HY-P1585

Gp100 (25-33), human 1 Publications Verification Hgp100 (25-33)	MHC	Cancer
Gp100 (25-33), human (Hgp100 (25-33)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human is a 9-amino acid (AA) epitope restricted by MHC class I H-2D ^b and recognized by the T cells. Gp100 (25-33), human has immunogenicity and induces specific T cells. Gp100 (25-33), human can be used for the cancer research, such as melanoma .

HY-P99922

Encelimab	LAG-3	Cancer
Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .

HY-P1585A

Gp100 (25-33), human TFA 1 Publications Verification Hgp100 (25-33) TFA	MHC	Cancer
Gp100 (25-33), human TFA (Hgp100 (25-33) (TFA)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human TFA is a 9-amino acid (AA) epitope restricted by MHC class I H-2D ^b and recognized by the T cells. Gp100 (25-33), human TFA has immunogenicity and induces specific T cells. Gp100 (25-33), human TFA can be used for the cancer research, such as melanoma .

HY-P11090

TpD	MHC	Inflammation/Immunology
TpD is a chimeric T-helper epitope. TpD has a special site that cathepsin can cut. Immunization with TpD produces a strong antibody response. TpD promotes long-term CD4 immune responses in animals and humans. TpD binds well to many human MHC class II types, mainly HLA-DRB1. It also binds some other HLA alleles like DRB3, DRB4, DRB5, DP, and DQ. TpD can be used to improve the immune response of peptide vaccines .

HY-P3070

H2-D b restricted epitopes VSV Nucleoprotein (52-59)	MHC	Infection Others
H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). H2-D b restricted epitopes VSV Nucleoprotein (52-59) binds to MHC class I molecules and presents itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs), which can recognize and kill cells expressing the corresponding antigen. H2-D b restricted epitopes VSV Nucleoprotein (52-59) can be used in the development of CTL vaccines against Ebola virus .

HY-P10295

p53 (232-240)	MDM-2/p53	Cancer
p53 (232-240) is a peptide segment of the 232-240 amino acid sequence of the human tumor suppressor protein p53. p53 (232-240) enhances its binding affinity to the Major histocompatibility complex (MHC), thereby enhancing the immunogenicity of this peptide to enhance the immune system's response to tumor antigens. p53 (232-240) can be used in the development of cancer vaccines and in the study of tumor cell recognition and clearance by the immune system .

HY-P990061

Polzastobart JTX 8064	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor .

HY-P99613

Favezelimab MK-4280	LAG-3	Cancer
Favezelimab (MK-4280) is a humanized monoclonal antibody targeting LAG-3. Favezelimab blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research in combination with the PD-L1 inhibitor Pembrolizumab (HY-P9902). Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-157280

AdCaPy	MHC	Inflammation/Immunology
AdCaPy is an MHC II antigen loading catalyst that accelerates the loading of peptide antigens by MHC II. AdCaPy is a useful molecular tool for enhancing immune responses .

HY-112026

1-Adamantaneethanol	Biochemical Assay Reagents	Inflammation/Immunology
1-Adamantaneethanol, a hapten, influences peptide binding by MHC II .

HY-157281

Photolumazine III PLIII	Transmembrane Glycoprotein	Inflammation/Immunology
Photolumazine III is a MHC class I related-1 molecule (MR1) antigen .

HY-P991142

Isuventatug	MHC	Inflammation/Immunology Cancer
Isuventatug is a monoclonal antibody targeting human MICA (MHC class I chain-related molecule A) and MICB (MHC class I chain-related molecule B). Isuventatug binds to MICA and MICB to regulate the interaction between immune cells and tumor cells, exerting antitumor activity. Isuventatug is promising for research of cancer immunotherapy .

HY-P5410

OVA-Q4 Peptide	MHC	Others
OVA-Q4 Peptide is a biological active peptide. (Q4 Peptide (SIIQFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)

HY-P10246

Hemoglobin (64-76)	MHC	Inflammation/Immunology
Hemoglobin 64-76 is a T cell inducing determinant, that binds to two different MHC class II molecules in distinct registers and lengths .

HY-P3639

SYLQDSVPDSFQD	TNF Receptor	Others
SYLQDSVPDSFQD, anchor-modified for high-affinity binding to DR4, is a DR4-restricted MHC class II peptide Tyrosinase .

HY-P5411

OVA-T4 Peptide SIITFEKL, OVA (257-264) Variant	MHC	Others
OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a biological active peptide. (T4 peptide (SIITFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)

HY-P4044

HBV Seq2 aa:28-39	HBV	Infection
HBV Seq2 aa:28-39 is a HBsAg peptide, which binds to major histocompatibility complex (MHC) class I molecules .

HY-P10296

p60 (217–225)	Endogenous Metabolite	Infection
p60 (217–225) is the subdominant epitope of Listeria monocytogenes, which combines with H-2K ^d MHC class I molecules .

HY-P99156

Relatlimab 3 Publications Verification BMS-986016	LAG-3	Cancer
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC₅₀ value of 0.67 nM and LAG-3/FGL1 interaction with an IC₅₀ value of 0.019 nM. Relatlimab can be used in research of cancer .

HY-P2455

LLO (91-99) Listeriolysin O (91-99)	Bacterial	Infection Inflammation/Immunology
LLO (91-99) (Listeriolysin O (91-99)) is an exotoxin and class I MHC-restricted T-cell epitope of listeriolysin (LLO). LLO (91-99) is processed by antigen-presenting cells, binds to MHC class I molecules and is presented to the cell surface. LLO (91-99) induces CTL responses and effectively eliminates Listeria from infected cells. LLO (91-99) can be used in the research of Listeria infections (e.g., listeriosis) .

HY-115464

NC1153	Endogenous Metabolite	Inflammation/Immunology
NC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity .

HY-P10433

EGFRvIII peptide	Apoptosis	Cancer
EGFRvIII peptide is an EGFRvIII-derived epitope for binding to MHC I molecules. EGFRvIII peptide induces apoptosis, and causes specific immune responses against glioblastoma, especially in combination with Flagellin B .

HY-170411

WNT7A-IN-1	Wnt	Cancer
WNT7A-IN-1 (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 significantly increases the expression of MHC-I and p-p65,while concurrently reducing the expression of active β-catenin. WNT7A-IN-1 (compound F) is also a photographic sensitizer in the green spectral region .

Cat. No.	Product Name	Target	Research Area

HY-P2494

OVA (55-62)	Peptides	Inflammation/Immunology
OVA 55-62 is a fragmented peptide of OVA (ovalbumin) antigen and can bind to the mouse MHC class I molecule, H2-Kb .

HY-P3715

OVA peptide 2 Publications Verification	MHC	Inflammation/Immunology
OVA peptide mainly exists in egg white, it is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA peptide has been widely studied in allergy research .

HY-P2527

Tyrosinase-related Protein 2 (TRP-2) (181-188)	Tyrosinase	Inflammation/Immunology
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a tyrosinase-related protein 2 (TRP-2)-derived peptide, corresponding to residues 180-188. Tyrosinase-related Protein 2 (TRP-2) (181-188) is the major reactive epitope within TRP-2 recognized by anti-B16 CTLs. Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide conforming to the MHC class I H2-Kb binding motif .

HY-P11062

M30 peptide MUT30	Peptides	Cancer
M30 peptide is an MHC class II epitope antigen that can be used in cancer nanovaccine research .

HY-P11061

M27 peptide	Peptides	Cancer
M27 peptide is an MHC class I epitope antigen that can be used in cancer nanovaccine research .

HY-P10441

S-palm P0(180–199)	Peptides	Inflammation/Immunology
S-palm P0(180-199) is a polypeptide that increases MHC Class II limiting reactions. S-palm P0(180-199) can be used to establish a model of chronic inflammatory demyelinating multiple radiculopathy (CIDP) .

HY-P5745

TYVPANASL	Transmembrane Glycoprotein	Cancer
TYVPANASL is a MHC I-binding CD8 T cell epitope of nine amino acids from HER2/neu. TYVPANASL can be used to prepare J-LEAPS vaccine .

HY-P10535

AAV-8 NSL epitope	Peptides	Others
The AAV-8 NSL epitope is a specific CD8+ T cell epitope identified from the capsid of an adeno-associated virus (AAV) serotype 8. The AAV-8 NSL epitope has a high affinity for MHC I molecules and is able to bind to MHC I molecules, thereby activating CD8+ T cells. The AAV-8 NSL epitope can be used to study the impact of T cell-mediated immune responses on AAV-mediated gene transfer .

HY-P5745A

TYVPANASL TFA	MHC EGFR	Cancer
TYVPANASL TFA is a MHC I-binding CD8 T cell epitope of nine amino acids from HER2/neu. TYVPANASL TFA can be used to prepare J-LEAPS vaccine .

HY-P6312

ESAT6 Epitope	Bacterial	Infection
ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC₅₀=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity .

HY-P1585

Gp100 (25-33), human 1 Publications Verification Hgp100 (25-33)	MHC	Cancer
Gp100 (25-33), human (Hgp100 (25-33)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human is a 9-amino acid (AA) epitope restricted by MHC class I H-2D ^b and recognized by the T cells. Gp100 (25-33), human has immunogenicity and induces specific T cells. Gp100 (25-33), human can be used for the cancer research, such as melanoma .

HY-P1585A

Gp100 (25-33), human TFA 1 Publications Verification Hgp100 (25-33) TFA	MHC	Cancer
Gp100 (25-33), human TFA (Hgp100 (25-33) (TFA)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human TFA is a 9-amino acid (AA) epitope restricted by MHC class I H-2D ^b and recognized by the T cells. Gp100 (25-33), human TFA has immunogenicity and induces specific T cells. Gp100 (25-33), human TFA can be used for the cancer research, such as melanoma .

HY-P11090

TpD	MHC	Inflammation/Immunology
TpD is a chimeric T-helper epitope. TpD has a special site that cathepsin can cut. Immunization with TpD produces a strong antibody response. TpD promotes long-term CD4 immune responses in animals and humans. TpD binds well to many human MHC class II types, mainly HLA-DRB1. It also binds some other HLA alleles like DRB3, DRB4, DRB5, DP, and DQ. TpD can be used to improve the immune response of peptide vaccines .

HY-P3070

H2-D b restricted epitopes VSV Nucleoprotein (52-59)	MHC	Infection Others
H2-D b restricted epitopes VSV Nucleoprotein (52-59) is a 9-mer peptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). H2-D b restricted epitopes VSV Nucleoprotein (52-59) binds to MHC class I molecules and presents itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs), which can recognize and kill cells expressing the corresponding antigen. H2-D b restricted epitopes VSV Nucleoprotein (52-59) can be used in the development of CTL vaccines against Ebola virus .

HY-P10295

p53 (232-240)	MDM-2/p53	Cancer
p53 (232-240) is a peptide segment of the 232-240 amino acid sequence of the human tumor suppressor protein p53. p53 (232-240) enhances its binding affinity to the Major histocompatibility complex (MHC), thereby enhancing the immunogenicity of this peptide to enhance the immune system's response to tumor antigens. p53 (232-240) can be used in the development of cancer vaccines and in the study of tumor cell recognition and clearance by the immune system .

HY-P10525

MBP Ac1-9 (4Y)	Peptides	Neurological Disease
MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis .

HY-P5410

OVA-Q4 Peptide	MHC	Others
OVA-Q4 Peptide is a biological active peptide. (Q4 Peptide (SIIQFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)

HY-P10246

Hemoglobin (64-76)	MHC	Inflammation/Immunology
Hemoglobin 64-76 is a T cell inducing determinant, that binds to two different MHC class II molecules in distinct registers and lengths .

HY-P3639

SYLQDSVPDSFQD	TNF Receptor	Others
SYLQDSVPDSFQD, anchor-modified for high-affinity binding to DR4, is a DR4-restricted MHC class II peptide Tyrosinase .

HY-P5412

LLO (190-201) Listeriolysin O 190 peptide	Peptides	Others
LLO (190-201) (Listeriolysin O 190 peptide) is a biological active peptide. (This peptide is a major histocompatibility complex class II (MHC-II)-restricted peptide, LLO190 (NEKYAQAYPNVS), from the listeriolysin O protein of Listeria monocytogenes, which generates an LLO190-specific Th response. This peptide subsequently challenge recombinant L. monocytogenes expressing the MHC-I-restricted epitope of ovalbumin (Ova257, SIINFEKL).)

HY-P5411

OVA-T4 Peptide SIITFEKL, OVA (257-264) Variant	MHC	Others
OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a biological active peptide. (T4 peptide (SIITFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)

HY-P4044

HBV Seq2 aa:28-39	HBV	Infection
HBV Seq2 aa:28-39 is a HBsAg peptide, which binds to major histocompatibility complex (MHC) class I molecules .

HY-P10296

p60 (217–225)	Endogenous Metabolite	Infection
p60 (217–225) is the subdominant epitope of Listeria monocytogenes, which combines with H-2K ^d MHC class I molecules .

HY-P2455

LLO (91-99) Listeriolysin O (91-99)	Bacterial	Infection Inflammation/Immunology
LLO (91-99) (Listeriolysin O (91-99)) is an exotoxin and class I MHC-restricted T-cell epitope of listeriolysin (LLO). LLO (91-99) is processed by antigen-presenting cells, binds to MHC class I molecules and is presented to the cell surface. LLO (91-99) induces CTL responses and effectively eliminates Listeria from infected cells. LLO (91-99) can be used in the research of Listeria infections (e.g., listeriosis) .

HY-P10433

EGFRvIII peptide	Apoptosis	Cancer
EGFRvIII peptide is an EGFRvIII-derived epitope for binding to MHC I molecules. EGFRvIII peptide induces apoptosis, and causes specific immune responses against glioblastoma, especially in combination with Flagellin B .

HY-P4193

AH1	MHC	Inflammation/Immunology Cancer
AH1 is a MHC class I-restricted tumor-specific antigenic peptide that can be presented by the murine MHC class I molecule L ^d. AH1 is derived from the envelope protein (gp70) of the endogenous ecotropic murine leukemia virus (MuLV) in mice. AH1 acts as an immunodominant CTL epitope in CT26 colon carcinoma. Additionally, AH1 is also an immunodominant CTL target for TS/A murine mammary adenocarcinoma, and its specific CTLs can mediate the killing and rejection of this tumor .

HY-P1489

OVA Peptide(257-264) Maximum Cited Publications 10 Publications Verification	MHC	Inflammation/Immunology
OVA Peptide(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb.

HY-P1489A

OVA Peptide(257-264) TFA Maximum Cited Publications 10 Publications Verification	MHC	Inflammation/Immunology
OVA Peptide(257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb.

HY-P1489B

OVA Peptide(257-264) acetate salt	MHC	Inflammation/Immunology
OVA Peptide(257-264) acetate salt is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb .

HY-120794

SC-67655	TNF Receptor	Inflammation/Immunology
SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC₅₀ of 50 nM. SC 67655 can be used for the study of autoimmune diseases .

HY-P1569

LCMV gp33-41 2 Publications Verification	Arenavirus	Inflammation/Immunology
LCMV gp33-41, the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .

HY-P1569A

LCMV gp33-41 TFA 2 Publications Verification	Arenavirus	Inflammation/Immunology
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .

HY-P4667

VLHDDLLEA	Peptides	Metabolic Disease
VLHDDLLEA is a peptide that can be isolated from the MHC complex HLA-A0201 molecule. VLHDDLLEA can be recognized by HLA-A0201-restricted cytotoxic T cells (CTLs). VLHDDLLEA can be used for research on graft versus host disease (GvHD) .

HY-P1745

InsB (9-23) Insulin B chain (9-23)	MHC	Inflammation/Immunology
InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes .

HY-P5453

CFP10 (71–85)	CD3	Others
CFP10 (71–85) is a biological active peptide. (CFP1071–85, that elicited IFN-γ production and CTL activity by both CD4+ and CD8+ T cells from persons expressing multiple MHC class II and class I molecules)

HY-P10245

Fusion glycoprotein (92-106)	RSV	Inflammation/Immunology
Fusion glycoprotein 92-106 is a polypeptide from fusion protein of respiratory syncytial virus (RSV). Fusion glycoprotein 92-106 acts as MHC class I-restricted CTL epitope, that all 15 amino acids are required for efficient recognition by cytotoxic T lymphocyte (CTL) .

HY-P2525

GAD65 (206-220)	MHC	Inflammation/Immunology
GAD65 (206-220) is glutamic acid decarboxylase (GAD) 65-derived peptide, corresponding to residues 180-188. GAD65 is presented to T cells in association with I-Ag7 MHC class II molecules and a major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus .

HY-P10382

M133 peptide	MHC	Inflammation/Immunology
M133 peptide is a coronavirus-specific CD4 T cell epitope. M133 peptide is immunodominant in mice infected with the neurotropic coronavirus (the JHM strain of mouse hepatitis virus). M133 peptide forms a complex with MHC II molecules, which is recognized by specific TCRs, thereby activating CD4 T cells .

HY-P10840

Tkip	JAK MHC	Inflammation/Immunology
Tkip is a JAK2 specific inhibitor. Tkip can bind the JAK2 autophosphorylation site, inhibit the JAK2 autophosphorylation and the phosphorylation of the IFN-γ receptor subunit IFNGR-1. Tkip inhibits the antiviral activity of IFN-γ and the expression of MHC Class I molecules. Tkip can be used to study the IFN-γ signaling pathway .

HY-P10582A

SIYNFEKL TFA	MHC	Inflammation/Immunology
SIYNFEKL TFA is a variant of major MHC class I-restricted epitope SIINFEKL. SIYNFEKL TFA is an antigenic peptide, that can stimulate specific T cells in experimental settings to study the competitive interaction between T cell. SIYNFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR), and can be used for detection of CD8+ T cells .

HY-P10581A

SIIVFEKL TFA	MHC	Inflammation/Immunology
SIIVFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. SIIVFEKL TFA is an antigenic peptide, that can stimulate specific T cells in experimental settings to study the competitive interaction between T cells. SIIVFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR), and can be used for detection of CD8+ T cells .

HY-P5502

Influenza NP (311-325)	Influenza Virus	Others
Influenza NP (311-325) is a biologically active peptide derived from the influenza virus nucleoprotein (NP). The NP protein is an MHC class II restricted epitope that elicits host immune responses during viral infection. Influenza NP (311-325) elicits the most potent interferon gamma (IFN-γ) production without stimulating CD8 T cells in mice.

HY-P1826

CLIP (86-100)	CD74	Inflammation/Immunology Cancer
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .

HY-P1826A

CLIP (86-100) (TFA)	Peptides	Inflammation/Immunology Cancer
CLIP (86-100) TFA is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .

HY-P10441A

S-palm P0(180–199) TFA 1 Publications Verification	Peptides	Inflammation/Immunology
S-palm P0(180–199) (TFA) is a peptide that enhances MHC II-restricted responses. S-palm P0(180–199) (TFA) can be used to establish models of chronic inflammatory demyelinating polyneuropathy (CIDP) and chronic experimental autoimmune neuritis (c-EAN). S-palm P0(180–199) (TFA) is used for studying autoimmune-mediated neuroinflammatory diseases .

HY-P10493

NY-ESO-1 (157-165) peptide	Amino Acid Derivatives	Cancer
NY-ESO-1 (157-165) peptide is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157-165) peptide can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. NY-ESO-1 (157-165) peptide is expressed in a variety of tumors and can be used as a target for tumor immunotherapy .

HY-P10493A

NY-ESO-1 (157-165) peptide TFA	Amino Acid Derivatives	Cancer
NY-ESO-1 (157-165) peptide (TFA) is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157-165) peptide (TFA) can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. NY-ESO-1 (157-165) peptide (TFA) is expressed in a variety of tumors and can be used as a target for tumor immunotherapy .

HY-P2507

NY-ESO-1 (87-111)	Peptides	Cancer
NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4 ⁺ T cells when presented in the context of HLA-DR and HLA-DP4 molecules .

HY-P2459

MOG (35-55), human	MHC	Neurological Disease
MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic via bind to H-2b class II MHC and recognized by T cells, but not encephalitogenic, and is only partially cross-reactive with mMOG35–55. MOG (35-55), human induces minimal clinical signs of EAE relative to the rodent peptide .

HY-P11058

OVA(250-264) OVAp	MHC	Cancer
OVA(250-264) (OVAvac) (OVAp) is an antigen peptide that can be from ovalbumin (OVA) presented by the class I *MHC* molecule, H-2Kb. OVA(250-264) combined withαMSLN (anti-MSLN antibody) significantly induces antigen-specific CD8 ⁺ T cell generation and infiltration for enhancing antitumor efficacy in orthotopic pancreatic cancer mice model. OVA(250-264) can be used for neoantigen vaccine development in pancreatic cancer immunotherapy research .

Cat. No.	Product Name	Target	Research Area

HY-P990832

*Anti-MHC* Class I Antibody (W6/32)**	MHC	Inflammation/Immunology
Anti-MHC Class I Antibody (W6/32) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human MHC Class I. Anti-MHC Class I Antibody (W6/32) reacts with the human major histocompatibility complex (MHC) class I, HLA-A, B, and C. Anti-MHC Class I Antibody (W6/32) increases adherence of monocytes to human endothelial cells. Anti-MHC Class I Antibody (W6/32) can be used for the research of immunology .

HY-P99135

*Anti-Mouse MHC* Class I (H-2Kb) Antibody (Y-3)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) is a mouse-derived IgG2b antibody inhibitor, targeting to mouse MHC Class I (H-2Kb). Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) reacts with the mouse H-2Kb, H-2Kk, H-2Kq, H-2Kr, H-2ks MHC class I alloantigens and not H-2Kd. Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) can block MHC Class I. Anti-Mouse MHC Class I (H-2Kb) Antibody (Y-3) can be used for immunology research .

HY-P990195

*Anti-Mouse MHC* Class I (H-2) Antibody (M1/42.3.9.8)**	MHC	Others
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) reacts with the mouse H-2 MHC class I alloantigen (all haplotypes). Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) can be used for the flow cytometry and immunofluorescence experiments .

HY-P990192

*Anti-Mouse MHC* Class I (H-2Kk) Antibody (AF3-12.1.3)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) reacts with the mouse H-2Kk MHC class I alloantigen. Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) can be used for the researches of inflammation and immunology, such as obliterative airway disease .

HY-P990194

*Anti-Mouse MHC* Class I (H-2Kd) Antibody (HB-159)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159) reacts with the mouse H-2Kd MHC class I alloantigen. Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159) can be used for immunology research, such as cardiac graft .

HY-P990190

*Anti-Swine MHC* Class I (SLAd) Antibody (74-11-10)**	MHC	Others
Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to *Swine MHC* Class I*. Anti-Swine MHC* Class I (SLAd) Antibody (74-11-10) reacts with the swine leucocyte antigen (SLA) class I. Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) can be used for the research of flow cytometry experiments .

HY-P990184

*Anti-Mouse MHC* Class II (βchain) Antibody (KL277)**	MHC	Others
Anti-Mouse MHC Class II (βchain) Antibody (KL277) is a hamster/mouse-derived IgG type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (βchain) Antibody (KL277) reacts with mouse MHC Class II haplotypes I-Ab, I-Ad, I-Ap, I-Aq, I-Abu, and I-Abw. Anti-Mouse MHC Class II (βchain) Antibody (KL277) does not react with I-Aa, I-Ak, I-Af, I-Aj, I-As, or I-Atl haplotypes. Anti-Mouse MHC Class II (βchain) Antibody (KL277) can be used for western blot experiments .

HY-P990188

*Anti-Mouse MHC* class II (I-A) Antibody (Y-3P)**	MHC	Inflammation/Immunology
Anti-Mouse MHC class II (I-A) Antibody (Y-3P) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC class II. Anti-Mouse MHC class II (I-A) Antibody (Y-3P) reacts with mouse MHC Class II haplotypes I-Ab, I-Af, I-Ap, I-Aq, I-Ar, I-As, I-Au, I-Av, and weakly with I-Ak. Anti-Mouse MHC class II (I-A) Antibody (Y-3P) blocks MHC class II and inhibits expansion of regulate T cells. Anti-Mouse MHC class II (I-A) Antibody (Y-3P) can be used for the immunology research .

HY-P990185

*Anti-Mouse/Rat MHC* Class II (I-Ek/RT1-D) Antibody (14-4-4S)**	MHC	Inflammation/Immunology Cancer
Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse/rat MHC Class II. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) reacts with mouse MHC Class II alloantigen I-Ek and the rat MHC class II alloantigen RT1D. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) blocks antigen presentation. Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) can be used for the research of immunology and cancer .

HY-P990187

*Anti-Mouse MHC* Class II (I-A/I-E) Antibody (M5/114)**	MHC Influenza Virus	Infection Inflammation/Immunology
Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) reacts with mouse MHC Class II haplotypes I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) does not react with I-Af, I-Ak, or I-As haplotypes. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) blocks MHC Class II and inhibit T cell generation. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) can be used for the researches of infection and immunology, such as influenza A virus (IAV) infection .

HY-P990189

*Anti-Monkey/Human MHC* class II (HLA-DR) Antibody (L243)**	MHC Apoptosis Reactive Oxygen Species (ROS)	Infection Cancer
Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to monkey/human MHC class II. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can inhibits tumor cells proliferation and induce apoptosis. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) increases cellular reactive oxygen species (ROS) and loss of mitochondrial membrane potential in human endothelial cells. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can be used for the researches of cancer and infection, such as lymphoma .

HY-P990813

*Anti-Mouse Nonclassical MHC* Class I molecule Qa-1b Antibody (4C2.4A7.5H11)**	MHC	Cancer
Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11) is a mouse-derived IgG1 antibody inhibito, targeting to mouse *Nonclassical MHC* Class I molecule Qa-1b*. Anti-Mouse Nonclassical MHC* Class I molecule Qa-1b Antibody (4C2.4A7.5H11) reacts with the mouse non-classical MHC class I molecule Qa-1b. Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11) can be used for the research of cancer, such as B16F10 tumor .

HY-P990191

*Anti-Mouse MHC* Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13))**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse MHC Class I. Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) reacts with the mouse H-2Kk and H-2Dk MHC class I alloantigens. Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) can be used for immunology research .

HY-P990186

*Anti-Mouse MHC* Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2)**	MHC	Others
Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) is a mouse-derived IgG2c κ type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) reacts with mouse MHC Class II haplotypes I-Ak, I-Ar, I-Af, I-As, and I-Ag7. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) does not react with I-Ab, I-Ad, I-Ap, or I-Aq haplotypes. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) blocks MHC Class II and inhibits antigen proliferation responses. Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) can be used for the research of immunology .

HY-P990193

*Anti-Mouse MHC* Class I (H-2Kd, H-2Dd) Antibody (34-1-2S)**	MHC	Inflammation/Immunology
Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) is an anti-mouse MHC Class I (H-2Kd, H-2Dd) IgG2a monoclonal antibody. Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) can block the interaction between Ly49 and MHC-I. Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) can be used for the construction of acute lung injury models .

HY-P990244

Anti-Rat FcRn heavy chain heterodimers Antibody (2G3)	Fc Receptor (FcR)	Inflammation/Immunology
Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is an anti-rat FcRn heavy chain heterodimers IgG1 monoclonal antibody. Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) effectively inhibits the binding of FcRn to IgG. Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is used in studies of the MHC class I heavy chain FcRn heterodimers and their interaction with IgG .

HY-P99129

Anti-Mouse CD8a Antibody (53-6.7) 2 Publications Verification	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD8a Antibody (53-6.7) is an anti-mouse CD8a IgG2a antibody inhibitor derived from host Rat. Anti-Mouse CD8a Antibody (53-6.7) binds to CD8αβ stabilizes a conformation with a higher affinity for interaction with MHC class I. Anti-Mouse CD8a Antibody (53-6.7) induces the phosphorylation and activation of TCR proximal signaling pathway components Lck and ZAP70 in polyclonal memory T cells. Anti-Mouse CD8a Antibody (53-6.7) depletes CD8+ T cells and neutralizes cytokine in mice .

HY-P99922

Encelimab	LAG-3	Cancer
Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .

HY-P990061

Polzastobart JTX 8064	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor .

HY-P990162

Anti-Mouse T15 VH and T15 VL regions of IgM Antibody (HB33)	Inhibitory Antibodies	Others
Anti-Mouse T15 VH and T15 VL regions of IgM Antibody (HB33) is an anti-mouse T15 VH and T15 VL regions of IgM IgG1 monoclonal antibody. Anti-Mouse T15 VH and T15 VL regions of IgM Antibody (HB33) is used in studies of the MHC class I heavy chain FcRn heterodimers and their interaction with IgG .

HY-P99613

Favezelimab MK-4280	LAG-3	Cancer
Favezelimab (MK-4280) is a humanized monoclonal antibody targeting LAG-3. Favezelimab blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research in combination with the PD-L1 inhibitor Pembrolizumab (HY-P9902). Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P991142

Isuventatug	MHC	Inflammation/Immunology Cancer
Isuventatug is a monoclonal antibody targeting human MICA (MHC class I chain-related molecule A) and MICB (MHC class I chain-related molecule B). Isuventatug binds to MICA and MICB to regulate the interaction between immune cells and tumor cells, exerting antitumor activity. Isuventatug is promising for research of cancer immunotherapy .

HY-P99156

Relatlimab 3 Publications Verification BMS-986016	LAG-3	Cancer
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC₅₀ value of 0.67 nM and LAG-3/FGL1 interaction with an IC₅₀ value of 0.019 nM. Relatlimab can be used in research of cancer .

HY-P99736

Miptenalimab BI-754111	LAG-3	Cancer
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (K_D: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II .

HY-P99027

Ieramilimab LAG525; IMP701; Hu5A8	LAG-3	Cancer
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules. Ieramilimab restores T-cell and NK-cell-mediated antileukemic immunity by reducing exhaustion and augmenting cytokine output and cytotoxicity. Ieramilimab increases the infiltration of cytotoxic T lymphocytes and reduces baseline densities of regulatory T cells (Tregs) and ADAM10-expressing tumor cells. Ieramilimab can be used for the study of various malignancies including melanoma, RCC, and advanced solid tumors .

HY-P990233

Anti-Mouse IFNγR/CD119 Antibody (GR-20)	IFNAR	Infection Inflammation/Immunology Cancer
Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IFNγR/CD119.Anti-Mouse IFNγR/CD119 Antibody (GR-20) reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. Anti-Mouse IFNγR/CD119 Antibody (GR-20) blocks the binding of IFNγ to CD119 therefore inhibiting IFNγ signaling. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma and C. trachomatis infected genital tract inflammation .

HY-P99573

Tebotelimab MGD-013	LAG-3	Inflammation/Immunology Cancer
Tebotelimab (MGD-013) is a humanized IgG4κ bispecific PD-1/LAG-3 dual-affinity re-targeting (DART) antibody. Tebotelimab binds cell-surface expressed PD-1 and LAG-3 with EC₅₀s of 1.65 nM and 0.41 nM in NS0 cells, respectively. Tebotelimab blocks PD-1/PD-L1, PD-1/PD-L2 and LAG-3/HLA (MHC-II) interactions and PD-1 signaling. Tebotelimab restores exhausted T-cell responses and and enhances antitumour immunity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7819

Pristane 1 Publications Verification Norphytane	Structural Classification other families Classification of Application Fields Terpenoids Marine natural products Source classification Other marine organisms Diterpenoids Plants Inflammation/Immunology Disease Research Fields	Others
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .

HY-B1618

Corticosterone 45+ Cited Publications 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B	Structural Classification Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Glucocorticoid Receptor Endogenous Metabolite iGluR
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .

HY-N7819R

Pristane (Standard)	Structural Classification other families Terpenoids Marine natural products Source classification Other marine organisms Diterpenoids Plants	Others
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .

Cat. No.	Product Name	Chemical Structure

HY-N7819S

Pristane-d40
Pristane-d₄₀ is the deuterium labeled Pristane . Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .

HY-126855S

Cholic acid 7-sulfate-d4

Cholic acid 7-sulfate-d₄ (7-Sulfocholic acid-d₄) is the deuterium labeled Cholic acid 7-sulfate (HY-126855). Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC₅₀=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83577

	MHC Class I Antibody (YA3322) Aw-68; HLA class I histocompatibility antigen; A-28 alpha chain; MHC class I antigen A68; HLA-A; MHC* class I antigen HLA A heavy chain	WB, IHC-P	Human
	MHC Class I Antibody (YA3322) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MHC Class I.

HY-P83195

	HLA Class 1 A Antibody (YA2940) Aw-68; HLA class I histocompatibility antigen; A-28 alpha chain; MHC class I antigen A68; HLA-A; MHC* class I antigen HLA A heavy chain	WB, IHC-P, ICC/IF, IP, FC	Human
	HLA Class 1 A Antibody (YA2940) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA Class 1 A.

HY-P83274

	HLA-C Antibody (YA3019) MHC; HLAC; HLC-C; D6S204; PSORS1; HLA-JY3	WB, IP	Human, Mouse
	HLA-C Antibody (YA3019) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-C.

HY-P83339

	HLA-DR Antibody (YA3084) 1 Publications Verification MLRW; HLA-DRA1; MHC class II antigen DRA; HLA class II histocompatibility antigen; DR alpha chain	WB, IHC-P, ICC/IF, FC	Human
	HLA-DR Antibody (YA3084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-DR.

HY-P84941

	HLA Class 1 ABC Antibody (YA4638) Antigen Presenting Molecule antibody; Cw1701 antibody; D6S204 antibody; FLJ27082 antibody; HLA A antibody; HLA B antibody; HLA C antibody; HLA class 1 A antibody; HLA class 1 B antibody; HLA class 1 C antibody; HLA JY3 antibody; HLAA antibody; HLAB antibody; HLAC antibody; HLC C antibody; Human Leucocyte Antigen C antibody; Major Histocompatibility Complex Class I A antibody; Major Histocompatibility Complex Class I B antibody; Major Histocompatibility Complex Class I C antibody; Major histocompatibility complex, class I, A + B + C antibody; MHC* class I antigen A1 antibody; MHC* Class I Antigen antibody; MHC class I antigen B7 antibody; MHC* class I antigen Cw1 antibody; MHC* class I HLA A antibody; MHC class I HLA B antibody; MHC class I HLA C antibody; MHC HLA ABC antibody; PSORS1 antibody	ICC/IF, FC	Human
	HLA Class 1 ABC Antibody (YA4638) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HLA Class 1 ABC.

HY-P83480

	HLA G Antibody (YA3225) HLA G antigen; MHC class I antigen G; HLA-G; HLA60; HLAG	WB	Human
	HLA G Antibody (YA3225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA G.

HY-P84044

	HLA-C Antibody (YA3741) MHC; HLAC; HLC-C; D6S204; PSORS1; HLA-JY3	IHC-P, ICC/IF, FC, ELISA	Human
	HLA-C Antibody (YA3741) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HLA-C.

HY-P83701

	HLA E Antibody (YA3437) HLA class I histocompatibility antigen E alpha chain antibody; EA1.2 antibody; EA2.1 antibody; HLA 6.2 antibody; HLA class I histocompatibility antigen alpha chain E antibody; HLA class I histocompatibility antigen E alpha chain precursor antibody; HLA class I histocompatibility antigen E alpha chain precursor antibody; HLA6.2 antibody; HLAE antibody; Lymphocyte antigen antibody; Major histocompatibility complex class I E antibody; MHC antibody; MHC class I antigen E antibody; MHC HLA E alpha 1 antibody; MHC HLA E alpha 2.1 antibody; QA1 antibody;	WB, IP, FC	Human
	HLA E Antibody (YA3437) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HLA E.

HY-P83760

	MICA+MICB Antibody (YA3560) HLA class I antigen antibody; FLJ36918 antibody; FLJ60820 antibody; MGC111087 antibody; MGC21250 antibody; MHC class I chain related gene A protein antibody; MIC A antibody; micA antibody; MICA_HUMAN antibody; OTTHUMP00000029088 antibody; PERB11.1 antibody; Stress inducible class I homolog antibody; MHC class I chain related protein B antibody; MICB antibody MICB_HUMAN antibody PERB11.2 antibody Stress inducible class I homolog antibody	WB, IP, FC	Human
	MICA+MICB Antibody (YA3560) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MICA+MICB.

HY-P81719

	MICA Antibody (YA1464) PERB11.1; MICA; HLA class I antigen antibody; FLJ36918 antibody; FLJ60820 antibody; MGC111087 antibody; MGC21250 antibody; MHC class I chain related gene A protein antibody	WB, IP, FC	Human
	MICA Antibody (YA1464) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MICA.

HY-P86901

	HLA DMB Antibody (YA6594) class II antigen HLA-DM beta chain antibody; class II histocompatibility antigen antibody; Class II histocompatibility antigen M beta chain antibody; D6S221E antibody; DMB antibody; HLA class II histocompatibility antigen DM beta chain antibody; HLA-DM histocompatibility type, beta chain antibody; M beta chain antibody; Major histocompatibility complex class II DM beta antibody; MHC class II antigen DMB antibody; class II antigen HLA-DM beta chain antibody; class II histocompatibility antigen antibody; Class II histocompatibility antigen M beta chain antibody; D6S221E antibody; DMB antibody; HLA class II histocompatibility antigen DM beta chain antibody; HLA-DM histocompatibility type, beta chain antibody; M beta chain antibody; Major histocompatibility complex class II DM beta antibody; MHC class II antigen DMB antibody; MHC class II antigen HLA DM beta chain antibody; MHC class II HLA DMB antibody; OTTHUMP00000029257 antibody; Really interesting new gene 7 protein antibody; RING 7 antibody; RING7 antibody;	WB, ICC/IF, IF-Tissue, FC	Human
	HLA DMB Antibody (YA6594) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA DMB.

HY-P82688

	HLA-DQA1 Antibody (YA2433) HLA-DQA1; CD; CELIAC1; DQ-A1; GSE; HLA-DQA; DQ alpha 1 chain; DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1	WB, IHC-P, IP	Human, Mouse, Rat
	HLA-DQA1 Antibody (YA2433) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-DQA1.

HY-P85015

	HLA-DR Antibody (YA4707) DASS-397D15.1 antibody; DR alpha chain antibody; DR alpha chain precursor antibody; DRA_HUMAN antibody; DRB1 antibody; DRB4 antibody; FLJ51114 antibody; Histocompatibility antigen HLA DR alpha antibody; Histocompatibility antigen HLA-DR alpha antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DR alpha chain antibody; HLA DR1B antibody; HLA DR3B antibody; HLA DRA antibody; HLA DRA1 antibody; HLA DRB1 antibody; HLA DRB3 antibody; HLA DRB4 antibody; HLA DRB5 antibody; HLA-DR histocompatibility type antibody; HLA-DRA antibody; HLADR4B antibody; HLADRA1 antibody; HLADRB antibody; Major histocompatibility complex class II DR alpha antibody; Major histocompatibility complex class II DR beta 1 antibody; Major histocompatibility complex class II DR beta 3 antibody; Major histocompatibility complex class II DR beta 4 antibody; Major histocompatibility complex class II DR beta 5 antibody; MGC117330 antibody; MHC cell surface glycoprotein antibody; MHC class II antigen DRA antibody; MHC II antibody; MLRW antibody; OTTHUMP00000029406 antibody; OTTHUMP00000029407 antibody; HLA-DRA nanobody;	ELISA	Human
	HLA-DR Antibody (YA4707) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HLA-DR.

HY-P87060

	Retinoid X Receptor beta/RXRB Antibody (YA6753) DAUD I6 antibody; DAUDI6 antibody; H 2RIIBP antibody; H2RIIBP antibody; MGC1831 antibody; MHC class I promoter binding protein antibody; NR2B2 antibody; Nuclear receptor subfamily 2 group B member 2 antibody; RCoR 1 antibody; RCoR1 antibody; DAUD I6 antibody; DAUDI6 antibody; H 2RIIBP antibody; H2RIIBP antibody; MGC1831 antibody; MHC class I promoter binding protein antibody; NR2B2 antibody; Nuclear receptor subfamily 2 group B member 2 antibody; RCoR 1 antibody; RCoR1 antibody; Retinoic acid receptor RXR beta antibody; Retinoic acid receptor RXR-beta antibody; Retinoid X receptor beta antibody; RXR beta antibody; Rxrb antibody; RXRB_HUMAN antibody; RXRbeta antibody;	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	Retinoid X Receptor beta/RXRB Antibody (YA6753) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Retinoid X Receptor beta/RXRB.

HY-P85898

	CD74 Antibody (YA5590) CD 74 antibody; CD74 antibody; CD74 antigen; invariant polypeptide of major histocompatibility complex; class II antigen-associated; antibody; CD74 antigen antibody; CD74 molecule antibody; CD74 molecule; major histocompatibility complex; class II invariant chain antibody; CLIP antibody; DHLAG antibody; Gamma chain of class II antigens antibody; HG2A_HUMAN antibody; HLA class II histocompatibility antigen gamma chain antibody; HLA DR antigens associated invariant chain antibody; HLA DR gamma antibody; HLA-DR antigens-associated invariant chain antibody; HLA-DR-gamma antibody; HLADG antibody; HLADR antigens associated invariant chain antibody; Ia antigen associated invariant chain antibody; Ia antigen-associated invariant chain antibody; Ia associated invariant chain antibody; Ia gamma antibody; Ii antibody; Invariant polypeptide of major histocompatibility complex class II antigen associated antibody; la-gamma antibody; Major histocompatibility complex class II invariant chain antibody; MHC HLA DR gamma chain antibody; MHC HLA-DR gamma chain antibody; p33 antibody; p35 antibody; Protein 41 antibody;	IHC-P, WB, ICC/IF, ELISA	Human
	CD74 Antibody (YA5590) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CD74.

HY-P81501

	KIR2DL3 Antibody (YA1246) KIR2DL3 ; CD158B2, KIRCL23, NKAT2; CD158b2; Killer cell immunoglobulin-like receptor 2DL3 ; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; NKAT2a; NKAT2b; Natural killer-associated transcript 2 (NKAT-2); p58 natural killer cell receptor clone CL-6 (p58 NK receptor CL-6); p58.2 MHC class-I-specific NK receptor	IHC-P	Human
	KIR2DL3 Antibody (YA1246) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KIR2DL3.

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Cat. No.	Product Name		Classification

HY-RS06198

HLA-C Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
HLA-C Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174646

Human IL10 mRNA		mRNA
Human IL10 mRNA encodes the human interleukin 10 (IL10) protein, a cytokine that produces primarily by monocytes and to a lesser extent by lymphocytes. IL10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production.

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