Search Result
Results for "
disodium
" in MedChemExpress (MCE) Product Catalog:
86
Biochemical Assay Reagents
66
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D0887
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IMP disodium salt; disodium inosinate
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Biochemical Assay Reagents
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Metabolic Disease
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Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .
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- HY-W250127
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Terephthalic acid disodium salt
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Biochemical Assay Reagents
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Cancer
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Disodium terephthalate (Terephthalic acid disodium salt) is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Disodium terephthalate can be used to build skin tumor models .
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- HY-F0001
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disodium NADH
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Endogenous Metabolite
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Metabolic Disease
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NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
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- HY-F0001R
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disodium NADH (Standard)
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
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- HY-B0345A
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Adenosine 5'-triphosphate disodium salt; disodium adenosine triphosphate
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Endogenous Metabolite
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Metabolic Disease
Inflammation/Immunology
Cancer
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ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
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- HY-Y1324
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disodium hydrogen phosphate dodecahydrate; disodium phosphate dodecahydrate
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Biochemical Assay Reagents
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Endocrinology
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Phosphoric acid disodium dodecahydrate is an inorganic compound and food additive. Phosphoric acid disodium dodecahydrate promotes gel formation, improves food texture and thermal properties of materials. Phosphoric acid disodium dodecahydrate induces glomerular calcification. Phosphoric acid disodium dodecahydrate can be used in kidney disease research .
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- HY-W015410
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Endogenous Metabolite
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Inflammation/Immunology
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Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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- HY-107794
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disodium clodronate tetrahydrate
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Others
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Neurological Disease
Inflammation/Immunology
Cancer
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Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl - competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC50 of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain .
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- HY-F0001A
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disodium NADH hydrate
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Endogenous Metabolite
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Metabolic Disease
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NADH disodium salt (Disodium NADH) hydrate is an orally active reduced coenzyme. NADH disodium salt hydrate is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt hydrate plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
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- HY-B0345AR
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Adenosine 5'-triphosphate disodium (Standard); disodium adenosine triphosphate (Standard)
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
Inflammation/Immunology
Cancer
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ATP disodium salt (Standard) is the analytical standard of ATP disodium salt (HY-B0345A). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
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- HY-107794R
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disodium clodronate tetrahydrate (Standard)
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Others
Reference Standards
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Neurological Disease
Inflammation/Immunology
Cancer
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Clodronate (disodium tetrahydrate) (Standard) is the analytical standard of Clodronate (disodium tetrahydrate). This product is intended for research and analytical applications. Clodronate disodium tetrahydrate (Disodium clodronate tetrahydrate) is first-generation bisphosphonate, with anti-osteoporotic, anti-inflammatory and analgesic effects. Clodronate disodium tetrahydrate is a selective, potent, reversible and Cl-competitive vesicular nucleotide transporter (VNUT) inhibitor, with an IC50 of 15.6 nM. Clodronate disodium tetrahydrate inhibits vesicular ATP release from neurons and reduces chronic neuropathic and inflammatory pain .
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- HY-W094516
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Wormwood acid disodium hexahydrate
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Biochemical Assay Reagents
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Others
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Disodium succinate hexahydrate (Wormwood acid (disodium hexahydrate)) is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-W015410R
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Reference Standards
Endogenous Metabolite
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Inflammation/Immunology
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Disodium succinate (Standard) is the analytical standard of Disodium succinate. This product is intended for research and analytical applications. Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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- HY-D0885B
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disodium creatine phosphate
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Endogenous Metabolite
MAP3K
Akt
Mitochondrial Metabolism
ERK
Apoptosis
ROS Kinase
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Metabolic Disease
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Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. .
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- HY-W250303A
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Hydroxybutanedioic acid disodium hydrate; disodium DL-malate hydrate; E 296 disodium hydrate
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Biochemical Assay Reagents
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Others
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Malic acid disodium hydrate is an organic compound that is commonly used as a food additive, buffering agent, and nutritional supplement. It contains sodium and malic acid. Malic acid disodium hydrate has a variety of properties that make it suitable for these applications, including the ability to enhance food flavor, improve texture, and regulate acidity. In addition, due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance, Malic acid disodium hydrate can be used as a dietary supplement .
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- HY-W015410S2
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Endogenous Metabolite
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Metabolic Disease
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Disodium succinate-d4 is the deuterium labeled Disodium succinate . Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism .
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- HY-100542
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disodium (R)-2-hydroxyglutarate
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Reactive Oxygen Species (ROS)
ATP Synthase
mTOR
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
Cancer
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D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid disodium is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling .
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- HY-100542R
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disodium (R)-2-hydroxyglutarate (Standard)
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Reference Standards
Reactive Oxygen Species (ROS)
ATP Synthase
mTOR
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
Cancer
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D-α-Hydroxyglutaric acid (disodium) (Standard) is the analytical standard of D-α-Hydroxyglutaric acid (disodium). This product is intended for research and analytical applications. D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid disodium is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling .
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- HY-W015410S
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Endogenous Metabolite
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Metabolic Disease
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Disodium succinate- 13C2 is the 13C labeled Disodium succinate . Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism .
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- HY-160120
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- HY-Y0308
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Biochemical Assay Reagents
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Others
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Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.
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- HY-W322022
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- HY-W654003
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disodium (R)-2-hydroxyglutarate-d5
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Reactive Oxygen Species (ROS)
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Neurological Disease
Inflammation/Immunology
Cancer
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D-α-Hydroxyglutaric acid-d5 disodium (Disodium (R)-2-hydroxyglutarate-d5) is the deuterium labeled D-α-Hydroxyglutaric acid disodium (HY-100542). D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid disodium is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling .
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- HY-N0666D
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- HY-F0002A
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disodium NADP
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Endogenous Metabolite
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Metabolic Disease
Inflammation/Immunology
Cancer
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NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
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- HY-B0540
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Sodium monofluorophosphate
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Biochemical Assay Reagents
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Others
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Disodium monofluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W105970
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disodium pyrophosphate; Sodium acid pyrophosphate; SAPP
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Biochemical Assay Reagents
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Inflammation/Immunology
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Sodium pyrophosphate (Disodium pyrophosphate), a food additive, is an inorganic compound. Sodium pyrophosphate has potential hematotoxic and immunotoxic effects .
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- HY-42247
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Glyoxal-sodium bisulfite monohydrate
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Drug Intermediate
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Others
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Disodium 1,2-dihydroxy-1,2-ethanedisulfonate (Glyoxal-sodium bisulfite) monohydrate is a drug intermediate for synthesis of various active compounds.
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- HY-15908
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disodium bicinchoninate
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Beta-secretase
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Neurological Disease
Cancer
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BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 value of 28 µM, a Ki value of 43 µM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) .
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- HY-Y0308E
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disodium hydrogen phosphate, for cell culture
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Biochemical Assay Reagents
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Others
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Sodium phosphate dibasic (Disodium hydrogen phosphate), for cell culture is a buffer and chelating agent. Sodium phosphate dibasic is used to adjust the pH of liquids. Sodium phosphate dibasic can be used in cell culture .
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- HY-Y0317E
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disodium sulfate (Pharmaceutical primary standard, USP)
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Biochemical Assay Reagents
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Others
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Sodium sulfate anhydrous (Disodium sulfate), can be widely used as a desiccant, pH regulator, etc. in biochemical experiments. It is a reference standard grade of the United States Pharmacopeia (USP), pharmaceutical primary standard.
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- HY-136883S
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disodium 3,3'-carbonylbis[4-hydroxy-6-methoxybenzenesulphonate]-d6
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Isotope-Labeled Compounds
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Others
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Benzophenone-9-d6 (Disodium 3,3'-carbonylbis[4-hydroxy-6-methoxybenzenesulphonate]-d6) is deuterium labeled Benzophenone-9 .
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- HY-W111522
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di-Sodium hydrogen phosphite, 98%
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Biochemical Assay Reagents
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Others
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Sodium phosphite dibasic pentahydrate, 98% is a metal chelating agent used to remove copper ions from water supplies.
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- HY-Y0308H
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disodium hydrogen phosphate, for molecular biology
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Biochemical Assay Reagents
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Others
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Sodium phosphate dibasic, for molecular biology is an inorganic salt that can be used for life science related research .
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- HY-Y0317H
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disodium sulfate, for cell culture
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Biochemical Assay Reagents
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Cancer
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Sodium sulfate anhydrous, for cell culture is a drying agent in organic synthesis, which can be used for cell culture .
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- HY-W094708C
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disodium hydrogen phosphate dihydrate, for molecular biology
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Biochemical Assay Reagents
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Others
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Sodium phosphate dibasic dihydrate, for molecular biology is an inorganic salt compound. Sodium phosphate dibasic dihydrate, for molecular biology is commonly used in molecular biology experiments and can be used as a buffer, nutritional supplement, and detergent.
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- HY-W094708D
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disodium hydrogen phosphate dihydrate, meets analytical specification of Ph. Eur. BP
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Biochemical Assay Reagents
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Others
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Sodium phosphate dibasic dihydrate, meets analytical specification of Ph. Eur. BP is an inorganic salt that can be used for life science related research .
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- HY-Y0317I
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disodium sulfate, meets analytical specification of Ph. Eur. BP USP
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Biochemical Assay Reagents
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Others
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Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
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- HY-Y0317IR
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disodium sulfate, meets analytical specification of Ph. Eur. BP USP (Standard)
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Reference Standards
Biochemical Assay Reagents
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Others
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Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP (Standard) is the analytical standard of Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP. This product is intended for research and analytical applications. Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
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- HY-114294A
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HMG-CoA disodium hydrate
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Biochemical Assay Reagents
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Metabolic Disease
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DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor .
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- HY-B0302A
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Etidronate disodium; HEDPA disodium; HEDP disodium
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Apoptosis
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Metabolic Disease
Cancer
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Etidronic acid (Etidronate) disodium is an orally and intravenously active bisphosphonate. Etidronic acid disodium inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid disodium has anticancer activity. Etidronic acid disodium is a chelating agent and can be used to remove heavy metal in water .
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- HY-B0302AR
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Etidronate disodium (Standard); HEDPA disodium (Standard); HEDP disodium (Standard)
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Reference Standards
Apoptosis
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Metabolic Disease
Cancer
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Etidronic acid (disodium) (Standard) is the analytical standard of Etidronic acid (disodium). This product is intended for research and analytical applications. Etidronic acid (Etidronate) disodium is an orally and intravenously active bisphosphonate. Etidronic acid disodium inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid disodium has anticancer activity. Etidronic acid disodium is a chelating agent and can be used to remove heavy metal in water .
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- HY-15068A
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FG9202 disodium
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iGluR
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Neurological Disease
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NBQX disodium (FG9202 disodium) is a highly selective and competitive AMPA receptor antagonist. NBQX disodium has neuroprotective and anticonvulsant activity .
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- HY-100196A
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PQQ disodium salt; Methoxatin disodium salt
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Endogenous Metabolite
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Inflammation/Immunology
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Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function .
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- HY-16637D
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Vitamin B9 disodium; Vitamin M disodium
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Endogenous Metabolite
DNA/RNA Synthesis
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Others
Neurological Disease
Cancer
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Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 5 g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .
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- HY-13630A
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BMY-40481 disodium
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Topoisomerase
Autophagy
Apoptosis
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Neurological Disease
Cancer
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Etoposide phosphate disodium (BMY-40481 disodium) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate disodium is the phosphate ester proagent of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate disodium induces cell cycle arrest, apoptosis, and autophagy.
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- HY-15066A
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FG9065 disodium
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iGluR
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Neurological Disease
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CNQX disodium (FG9065 disodium) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. CNQX disodium is a competitive non-NMDA receptor antagonist . CNQX disodium blocks the expression of fear-potentiated startle in rats .
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- HY-A0213B
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Tiludronic acid disodium hemihydrate
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Proton Pump
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Metabolic Disease
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Tiludronate (Tiludronic Acid) disodium hemihydrate, an orally active bisphosphonate, can act an osteoregulator. Tiludronate disodium hemihydrate is used for the research of the metabolic bone disorders. Tiludronate disodium hemihydrate is a potent inhibitor of the osteoclast vacuolar H +-ATPase. Antiresorptive and anti-inflammatory properties .
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- HY-10820A
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LY231514 disodium
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Antifolate
Autophagy
Apoptosis
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Cancer
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Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
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- HY-W010771
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dCTP disodium; 2′-Deoxycytidine-5′-triphosphate disodium
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Biochemical Assay Reagents
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Others
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Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-107328
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- HY-W010970
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5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt
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Endogenous Metabolite
iGluR
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Neurological Disease
Metabolic Disease
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5'-Guanylic acid disodium salt is the disodium salt form of 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid disodium salt is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid disodium salt regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid disodium salt is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid disodium salt also causes neuronal cell death at high concentrations .
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- HY-17352A
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Ro 61-1790 disodium; VML 588 disodium; AXV-034343 disodium
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Endothelin Receptor
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Cardiovascular Disease
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Clazosentan disodium (Ro 61-1790) is a selective endothelin A (ETA) receptor antagonist. Clazosentan disodium inhibits ET-1-mediated vasoconstriction. Clazosentan disodium prevents cerebral vasospasm, vasospasm-related cerebral infarction .
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- HY-17556A
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Leucovorin disodium
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Endogenous Metabolite
Antifolate
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Cancer
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Folinic acid (Leucovorin) disodium is a biological folic acid and is a forms of vitamin B9. Folinic acid disodium is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity. Folinic acid disodium and Sfluorouracil adjuvant chemotherapy shows effective in colon carcinoma .
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- HY-B1829AR
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Dexamethasone 21-phosphate disodium (Standard)
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Glucocorticoid Receptor
Reference Standards
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Inflammation/Immunology
Endocrinology
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Dexamethasone phosphate (disodium) (Standard) is the analytical standard of Dexamethasone phosphate (disodium). This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist .
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- HY-136548B
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TFV-DP disodium
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HIV
Reverse Transcriptase
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Infection
Inflammation/Immunology
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Tenofovir diphosphate disodium is an antiretroviral agent. Tenofovir diphosphate disodium is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate disodium can be used for the research of AIDS .
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- HY-15068AR
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iGluR
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Neurological Disease
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NBQX (disodium) (Standard) is the analytical standard of NBQX (disodium). This product is intended for research and analytical applications. NBQX disodium (FG9202 disodium) is a highly selective and competitive AMPA receptor antagonist. NBQX disodium has neuroprotective and anticonvulsant activity .
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- HY-B0645R
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- HY-B0320AR
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Cromoglycate disodium (Standard); Cromoglicic acid disodium (Standard); FPL-670 (Standard)
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Reference Standards
GSK-3
NF-κB
Amyloid-β
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Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
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Cromolyn disodium (Standard) (Cromoglycate disodium (Standard)) is the analytical standard of Cromolyn disodium (HY-B0320A). This product is intended for research and analytical applications. Cromolyn (Cromoglycate) disodium is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn disodium is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn disodium can be used in the research of bronchial asthma. In addition, Cromolyn disodium has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
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- HY-W011152
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dCMP disodium
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Endogenous Metabolite
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Others
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2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .
|
-
- HY-14521A
-
|
DDATHF disodium
|
Antifolate
Apoptosis
Caspase
Bcl-2 Family
|
Cancer
|
|
Lometrexol (DDATHF) disodium, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol disodium can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol disodium has anticancer activity. Lometrexol disodium also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor .
|
-
- HY-13718A
-
|
H-Glu-Trp-OH disodium; L-Glutamyl-L-tryptophan disodium
|
VEGFR
HCV
Endogenous Metabolite
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Oglufanide (H-Glu-Trp-OH) disodium is a dipeptide immunomodulator isolated from calf thymus. Oglufanide disodium inhibits vascular endothelial growth factor (VEGF). Oglufanide disodium can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide disodium shows antitumor and anti-angiogenesis activities .
|
-
- HY-13777B
-
|
Zoledronate disodium tetrahydrate; CGP 42446 disodium tetrahydrate; CGP42446A disodium tetrahydrate; ZOL 446 disodium tetrahydrate
|
Apoptosis
Autophagy
Bacterial
|
Metabolic Disease
Cancer
|
|
Zoledronic Acid (Zoledronate) disodium tetrahydrate is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid disodium tetrahydrate inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid disodium tetrahydrate also has anti-cancer effects .
|
-
- HY-135655
-
|
SPR720 disodium; pVXc-486 disodium
|
Bacterial
|
Infection
|
|
Fobrepodacin (SPR720) disodium is an orally active and potent phosphate proagent of SPR719 (VXc-486; HY-12930). Fobrepodacin disodium has potent bactericidal activities in vivo .
|
-
- HY-D0994A
-
|
4-MUP disodium; MUP disodium
|
Phosphatase
|
Others
|
|
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
|
-
- HY-A0294AR
-
|
MK-0826 disodium (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem (disodium) (Standard) is the analytical standard of Ertapenem (disodium). This product is intended for research and analytical applications. Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].
|
-
- HY-13570CR
-
|
Betamethasone 21-phosphate disodium salt (Standard); Vista-Methasone (Standard)
|
Glucocorticoid Receptor
Reference Standards
|
Others
|
|
Betamethasone disodium phosphate (Standard) is the analytical standard of Betamethasone disodium phosphate. This product is intended for research and analytical applications. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids .
|
-
- HY-B0645
-
|
Prednisolone 21-phosphate disodium
|
Glucocorticoid Receptor
|
Inflammation/Immunology
Endocrinology
|
|
Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Prednisolone disodium phosphate can be rapidly and completely hydrolyzed to Prednisolone in the plasma .
|
-
- HY-B0320A
-
|
Cromoglycate disodium; Cromoglicic acid disodium; FPL-670
|
GSK-3
NF-κB
Amyloid-β
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Cromolyn (Cromoglycate) disodium is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn disodium is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn disodium can be used in the research of bronchial asthma. In addition, Cromolyn disodium has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
|
-
- HY-105168
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-13570C
-
|
Betamethasone 21-phosphate disodium salt; Vista-Methasone
|
Glucocorticoid Receptor
|
Others
|
|
Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids .
|
-
- HY-B2176A
-
|
Adenosine-5'-triphosphate disodium trihydrate
|
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-W010270A
-
-
- HY-Y0682A
-
|
EDTA disodium dihydrate
|
Biochemical Assay Reagents
Bacterial
SOD
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .
|
-
- HY-10820AS
-
|
LY231514-dd5 disodium
|
Isotope-Labeled Compounds
Antifolate
Autophagy
Apoptosis
|
Cancer
|
|
Pemetrexed-d5 disodium is the deuterium labeled Pemetrexed disodium. Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
|
-
- HY-139597R
-
|
BRL 17421 disodium (Standard)
|
Reference Standards
Bacterial
|
Infection
Inflammation/Immunology
|
|
Temocillin (disodium) (Standard) is the analytical standard of Temocillin (disodium). This product is intended for research and analytical applications. Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity .
|
-
- HY-122307A
-
|
DAN-603 disodium
|
Bacterial
|
Metabolic Disease
|
|
Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon .
|
-
- HY-W010735R
-
|
Adenosine 5'-triphosphate disodium salt hydrate (Standard)
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
ATP (disodium salt hydrate) (Standard) is the analytical standard of ATP (disodium salt hydrate). This product is intended for research and analytical applications. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-Y0682AR
-
|
EDTA disodium dihydrate (Standard)
|
Biochemical Assay Reagents
Reference Standards
Bacterial
SOD
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Ethylenediaminetetraacetic acid (disodium dihydrate) (Standard) is the analytical standard of Ethylenediaminetetraacetic acid (disodium dihydrate). This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research [4] .
|
-
- HY-B0302AS
-
-
- HY-137724A
-
|
Cyclic-di-IMP disodium
|
STING
|
Cancer
|
|
C-di-IMP disodium is a STING agonist. C-di-IMP disodium can be used in tumor research .
|
-
- HY-B0657A
-
|
Clodronate disodium salt
|
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Clodronic acid (Clodronate) disodium salt, a first-generation bisphosphonate, is orally active osteoclastic bone resorption inhibitor. Clodronic acid disodium salt can be used in high bone turnover states, Paget ’s disease and osteolytic bone metastases .
|
-
- HY-136072
-
|
QPX7728 disodium
|
Bacterial
|
Infection
|
|
Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range .
|
-
- HY-A0294A
-
|
MK-0826 disodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
- HY-B0174R
-
-
- HY-W127530R
-
|
alpha-Tocopherol phosphate disodium (Standard); TocP disodium (Standard); Vitamin E phosphate disodium (Standard)
|
Reference Standards
Apoptosis
Reactive Oxygen Species (ROS)
|
Cardiovascular Disease
Cancer
|
|
α-Tocopherol phosphate (Standard) (alpha-Tocopherol phosphate (Standard)) disodium is the analytical standard of α-Tocopherol phosphate disodium (HY-W127530). This product is intended for research and analytical applications.
α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity .
|
-
- HY-A0294AS
-
-
- HY-14519A
-
|
Amethopterin disodium; CL14377 disodium; WR19039 disodium
|
Antifolate
DNA/RNA Synthesis
ADC Payload
Apoptosis
Bacterial
|
Inflammation/Immunology
Cancer
|
|
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .
|
-
- HY-13777C
-
|
CGP 42446 disodium; CGP42446A disodium; ZOL 446 disodium
|
Apoptosis
|
Cancer
|
|
Zoledronate (CGP 42446) disodium is a potent bisphosphonate that effectively inhibits osteoclastogenesis, reducing bone turnover and stabilizing the bone matrix. Zoledronate disodium has demonstrated notable effectiveness in managing Paget's disease of bone by suppressing metabolic activity and alleviating bone pain. Zoledronate disodium is being investigated in the ongoing ZiPP trial for its potential to prevent disease progression in patients with Paget's disease. Zoledronate disodium also exhibits diverse anti-tumor effects in osteosarcoma, further highlighting its multifunctional therapeutic applications.
|
-
- HY-131605B
-
|
GCV-TP disodium
|
CMV
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Ganciclovir triphosphate (GCV-TP) disodium is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate disodium is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate disodium has an IC50 of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate disodium has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition .
|
-
- HY-W018746R
-
|
Ethylenediaminetetraacetic acid disodium (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
EDTA (disodium) (Standard) is the analytical standard of EDTA (disodium). This product is intended for research and analytical applications. EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
- HY-112174
-
|
UDP-α-D-N-Acetylglucosamine disodium
|
OGT
|
Metabolic Disease
|
|
UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).
|
-
- HY-W587430
-
|
Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium
|
HIV
GPR39
|
Infection
Inflammation/Immunology
|
|
Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 47.9 and 66.8 μM (absence of Zn 2+) and 8 and 8.7 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .
|
-
- HY-N7097
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sulbenicillin disodium is the disodium salt of Sulbenicillin. Sulbenicillin is a Penicillin antibiotic with antibacterial activity against a number of mucoid and non-mucoid strains of Pseudomonas aeruginosa .
|
-
- HY-B2176AR
-
|
|
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
ATP (disodium trihydrate) (Standard) is the analytical standard of ATP (disodium trihydrate). This product is intended for research and analytical applications. ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-B1367
-
|
|
Gap Junction Protein
Orthopoxvirus
11β-HSD
|
Infection
Inflammation/Immunology
|
|
Carbenoxolone disodium is the active metabolite of Glycyrrhizic acid (HY-N0184) and the inhibitor of human 11β-HSD and bacterial 3α, 20β-HSD . Carbenoxolone disodium is an uncoupling agent for gap junctions and a potent inhibitor of Vaccinia virus replication . Carbenoxolone disodium is used for the study of peptic, esophageal and oral ulceration and inflammation. Carbenoxolone disodium inhibits Vaccinia virus replication.
|
-
- HY-W127530
-
|
alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium
|
Apoptosis
Reactive Oxygen Species (ROS)
|
Cardiovascular Disease
Cancer
|
|
α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity .
|
-
- HY-D0885D
-
|
|
Endogenous Metabolite
MAP3K
Akt
Mitochondrial Metabolism
ERK
Apoptosis
ROS Kinase
|
Metabolic Disease
|
|
Phosphocreatine (disodium hydrate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium hydrate) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium hydrate) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium hydrate) Phosphocreatine (disodium hydrate) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. .
|
-
- HY-123490
-
|
INS50589
|
P2Y Receptor
|
Inflammation/Immunology
|
|
Regrelor disodium (INS 50589) is a platelet P2Y12 receptor antagonist. Regrelor disodium is a well-tolerated, reversible ADP competitive antagonist. Regrelor disodium inhibits cell proliferation. Regrelor disodium can be used in inflammation-related research .
|
-
- HY-103267R
-
|
|
Reference Standards
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
|
S32826 (disodium) (Standard) is the analytical standard of S32826 (disodium). This product is intended for research and analytical applications. S32826 disodium is a potent autotaxin inhibitor, with an IC50 of 8.8 nM. S32826 disodium shows similar inhibitory effects at various autotaxin isoforms (α, β and γ). S32826 disodium inhibits LPA release from adipocytes .
|
-
- HY-171909A
-
|
GroPIns-4-P disodium
|
Adenylate Cyclase
ROCK
|
Cancer
|
|
Glycerophosphoinositol 4-phosphate (GroPIns-4-P) disodium is a metabolite of phospholipase A and an inhibitor of adenylylcyclase. Glycerophosphoinositol 4-phosphate disodium can regulate cAMP-dependent cellular functions. Glycerophosphoinositol 4-phosphate disodium can also induce the formation of membrane ruffles and stress fibers in serum-starved Swiss 3T3 cells by activating the small GTPases Rac and Rho, respectively. Glycerophosphoinositol 4-phosphate disodium can be used in research on cancer cell motility and invasiveness .
|
-
- HY-12590
-
-
- HY-D0075
-
|
|
Fluorescent Dye
|
Others
|
|
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .
|
-
- HY-113149A
-
|
|
Endogenous Metabolite
Reactive Oxygen Species (ROS)
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Argininosuccinic acid disodium is an intermediate metabolite in the urea cycle, and its level is associated with argininosuccinic aciduria. Argininosuccinic acid disodium can induce oxidative stress, leading to lipid and protein oxidation, reduction of glutathione, and decrease in antioxidant enzyme activity. Argininosuccinic acid disodium can be converted into guanidinosuccinic acid, a nitric oxide mimic, under the action of nitric oxide-derived free radicals. Argininosuccinic acid disodium can be used in the research of metabolic diseases, renal failure, nervous system diseases, etc .
|
-
- HY-W013707
-
|
Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cytidine-5'-triphosphate disodium dihydrate (5'-CTP disodium dihydrate) is a molecule of high energy, and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation .
|
-
- HY-121538A
-
|
|
Epoxide Hydrolase
PPAR
|
Cardiovascular Disease
|
|
CUDA disodium is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively . CUDA disodium selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA disodium may be valuable for the research of cardiovascular disease .
|
-
- HY-103267
-
|
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
|
S32826 disodium is a potent autotaxin inhibitor, with an IC50 of 8.8 nM. S32826 disodium shows similar inhibitory effects at various autotaxin isoforms (α, β and γ). S32826 disodium inhibits LPA release from adipocytes .
|
-
- HY-16502
-
|
Transcrocetin disodium; trans-Crocetin disodium
|
iGluR
|
Cancer
|
|
Crocetin (Transcrocetin) disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.
|
-
- HY-D0885BR
-
|
|
Endogenous Metabolite
MAP3K
Akt
Mitochondrial Metabolism
ERK
Apoptosis
ROS Kinase
|
Metabolic Disease
|
|
Phosphocreatine (disodium) (Standard) is the analytical standard of Phosphocreatine (disodium). This product is intended for research and analytical applications. Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. .
|
-
- HY-17383A
-
|
|
Antifolate
|
Neurological Disease
|
|
Levomefolate disodium is an orally active, BBB-penetrable and active form of folic acid. Levomefolate disodium can be used as a food supplement for folic acid and in the research of neural tube defect diseases .
|
-
- HY-113038A
-
|
2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium
|
Histone Demethylase
Endogenous Metabolite
|
Cancer
|
|
α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
|
-
- HY-W010907
-
|
|
GPR35
ERK
|
Neurological Disease
|
|
Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect .
|
-
- HY-W008940R
-
|
Cytidine diphosphate disodium (Standard)
|
Endogenous Metabolite
Reference Standards
|
Metabolic Disease
|
|
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
|
-
- HY-W769288
-
|
LY231514 disodium-13C5
|
Isotope-Labeled Compounds
Apoptosis
Antifolate
Autophagy
|
Cancer
|
|
Pemetrexed disodium- 13C5 (LY231514 disodium- 13C5) is the 13C-labeled Pemetrexed disodium (HY-10820A). Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
|
-
- HY-107921R
-
|
EDTA calcium disodium salt,98% (Standard); Adsorbonac,98% (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
EDTA Calcium disodium,98% (Standard) is the analytical standard of EDTA Calcium disodium,98%. This product is intended for research and analytical applications. EDTA Calcium disodium, 98% (EDTA calcium disodium salt, 98%; Adsorbonac, 98%) is a chelating agent for calcium and other metal ions, preventing them from participating in chemical reactions. It can effectively remove metal ions from solutions, preventing them from interfering with experimental processes.
|
-
- HY-W013098
-
|
5'-Dexoadenosine triphosphate disodium
|
Biochemical Assay Reagents
|
|
|
2'-Deoxyadenosine 5'-triphosphate disodium (5'-Dexoadenosine triphosphate disodium) is a nucleotide with important biological activities and can serve as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. 2'-Deoxyadenosine 5'-triphosphate disodium plays a key role in DNA synthesis and reverse transcription. 2'-Deoxyadenosine 5'-triphosphate disodium is also widely used in in vitro reactions in molecular biology research.
|
-
- HY-14519AR
-
|
|
Antifolate
DNA/RNA Synthesis
ADC Payload
Apoptosis
Bacterial
|
Inflammation/Immunology
Cancer
|
|
Methotrexate (disodium) (Standard) is the analytical standard of Methotrexate (disodium). This product is intended for research and analytical applications. Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .
|
-
- HY-N1443
-
|
|
Endogenous Metabolite
Apoptosis
|
Metabolic Disease
Cancer
|
|
Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer .
|
-
- HY-N7701E
-
|
|
Fungal
|
Infection
|
|
L-Diguluronic acid disodium is a linear polysaccharide copolymer composed of two L-guluronic acid. L-Diguluronic acid disodium can be used to form Alginate. L-Diguluronic acid disodium is a generic name of unbranched polyanionic polysaccharides and it can be used for the research of antifungal agents delivery carries .
|
-
- HY-109174A
-
|
CPX-POM disodium
|
γ-secretase
|
Metabolic Disease
Cancer
|
|
Fosciclopirox disodium suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox disodium selectively delivers the active metabolite, Ciclopirox (HY-B0450), to the entire urinary tract. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies .
|
-
- HY-B0345AS
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
ATP- 18O4 (disodium salt) is the 18O labeled ATP disodium salt . ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-W010735
-
|
Adenosine 5'-triphosphate disodium salt hydrate
|
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-136664A
-
-
- HY-W392263
-
-
- HY-112174S
-
|
UDP-α-D-N-Acetylglucosamine-13C disodium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
UDP-GlcNAc- 13C (disodium) is the 13C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O .
|
-
- HY-110382
-
|
c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium
|
STING
Endogenous Metabolite
|
Cancer
|
|
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .
|
-
- HY-B1829A
-
-
- HY-111999B
-
|
|
STING
|
Cancer
|
|
E7766 disodium is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 disodium shows potent pan-genotypic and antitumor activities .
|
-
- HY-113238A
-
|
Sulfolithocholic acid disodium; LCAS disodium
|
GPR39
|
Others
Inflammation/Immunology
|
|
Lithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 41 and 42.4 (absence of Zn 2+) and 0.88 and 0.97 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Lithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Lithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-W018746
-
|
Ethylenediaminetetraacetic acid disodium
|
Biochemical Assay Reagents
|
Others
|
|
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
- HY-10820BR
-
|
LY231514 disodium heptahydrate (Standard)
|
Reference Standards
Antifolate
Autophagy
|
Cancer
|
|
Pemetrexed (disodium heptahydrate) (Standard) is the analytical standard of Pemetrexed (disodium heptahydrate). This product is intended for research and analytical applications. Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
|
-
- HY-W073082
-
|
Triglycollamic acid disodium salt
|
Biochemical Assay Reagents
|
Others
|
|
Nitrilotriacetic acid disodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W013159
-
|
5′-dGMP disodium
|
Endogenous Metabolite
Nucleoside Antimetabolite/Analog
|
Metabolic Disease
|
|
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
|
-
- HY-13038R
-
|
|
Syk
FLT3
|
Inflammation/Immunology
Cancer
|
|
Fostamatinib Disodium (Standard) is the analytical standard of Fostamatinib Disodium. This product is intended for research and analytical applications. Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
|
-
- HY-130115A
-
|
|
STING
|
Cancer
|
|
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy .
|
-
- HY-W013175R
-
|
5'-Uridylic acid disodium salt (Standard)
|
Endogenous Metabolite
Cholinesterase (ChE)
Reference Standards
Potassium Channel
Apoptosis
|
Cardiovascular Disease
Metabolic Disease
|
|
Uridine 5'-monophosphate (disodium salt) (Standard) is the analytical standard of Uridine 5'-monophosphate (disodium salt). This product is intended for research and analytical applications. Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
|
-
- HY-12885A
-
|
ADU-S100 disodium salt; MIW815 disodium salt; ML RR-S2 CDA disodium salt
|
STING
|
Inflammation/Immunology
Cancer
|
|
2’3’-c-di-AM(PS)2 (Rp,Rp) disodium salt (ADU-S100 disodium salt) is an activator of stimulator of interferon genes (STING).
|
-
- HY-W742557
-
-
- HY-W013100R
-
|
Cytidine triphosphate disodium (Standard); 5'-CTP disodium (Standard)
|
Reference Standards
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Metabolic Disease
|
|
Cytidine-5'-triphosphate (Cytidine triphosphate) (Standard) disodium is the analytical standard of Cytidine-5'-triphosphate disodium (HY-W013100). This product is intended for research and analytical applications. Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
|
-
- HY-D0199R
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
|
-
- HY-N11287A
-
|
|
Endogenous Metabolite
|
Others
|
|
UDP-xylose disodium is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose disodium synthase (UXS). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose disodium participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2].
|
-
- HY-D0199
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
|
-
- HY-13038
-
|
R788(disodium)
|
Syk
FLT3
|
Inflammation/Immunology
Cancer
|
|
Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
|
-
- HY-129560
-
-
- HY-W749867
-
|
Calcium disodium EDTA dihydrate
|
Bacterial
|
Infection
Others
|
|
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .
|
-
- HY-166220
-
-
- HY-B0525AR
-
|
Sodium carbenicillin (Standard)
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
|
Carbenicillin (disodium) (Standard) is the analytical standard of Carbenicillin (disodium). This product is intended for research and analytical applications. Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .
|
-
- HY-W096122
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DTSSP Crosslinker disodium is a protein cross-linker containing a disulfide bond. DTSSP Crosslinker disodium can react with sidechains of amino acids that are within close proximity .
|
-
- HY-137829
-
|
|
Endogenous Metabolite
|
Others
|
|
5-Methyltetrahydrofolic acid disodium is the metabolite of Folinic acid (Leucovorin) (HY-17556). 5-Methyltetrahydrofolic acid disodium is involved in one-carbon metabolism and the transfer of methyl groups .
|
-
- HY-134367
-
-
- HY-112502A
-
|
Adenosine 5'-(α,β-methylene)diphosphate disodium
|
CD73
|
Cancer
|
|
MethADP disodium is a specific CD73 inhibitor.
|
-
- HY-W766920
-
-
- HY-W250119
-
|
EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
|
Biochemical Assay Reagents
|
Others
|
|
Calcium disodium edetate hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B1654AR
-
|
FAD disodium salt (Standard); FAD-Na2 (Standard)
|
Reference Standards
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Flavin adenine dinucleotide (disodium salt) (Standard) is the analytical standard of Flavin adenine dinucleotide (disodium salt). This product is intended for research and analytical applications. Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
|
-
- HY-W779068
-
-
- HY-W011012R
-
|
|
Reference Standards
Adenosine Receptor
|
Metabolic Disease
|
|
Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
- HY-113238AS
-
|
Sulfolithocholic acid-d4 disodium
|
Isotope-Labeled Compounds
|
Others
|
|
Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium .
|
-
- HY-W011012
-
|
|
Adenosine Receptor
|
Metabolic Disease
|
|
Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
- HY-W787630
-
-
- HY-W342120
-
-
- HY-W010854
-
|
dADP disodium
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .
|
-
- HY-128738R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
Thymidine-5'-monophosphate (disodium) salt (Standard) is the analytical standard of Thymidine-5'-monophosphate (disodium) salt. This product is intended for research and analytical applications. Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
|
-
- HY-112169A
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines .
|
-
- HY-141412
-
|
3-Phospho-D-glyceric acid disodium
|
Enolase
Phosphoglycerate Dehydrogenase (PHGDH)
MDM-2/p53
Apoptosis
|
Infection
|
|
D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis .
|
-
- HY-134433A
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .
|
-
- HY-134354A
-
|
ADP-ribose-pNP disodium
|
Poly(ADP-ribose) Glycohydrolase (PARG)
|
Others
|
|
pNP-ADPr disodium is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr disodium can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes .
|
-
- HY-D1520
-
|
|
Phosphatase
|
Others
|
|
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .
|
-
- HY-137135A
-
|
|
Phosphatase
Apoptosis
|
Cancer
|
|
Cantharidic acid disodium is the hydrolysis product of the acid anhydride Cantharidin that induces apoptosis in various human cancer cells. Cantharidic acid disodium is a selective protein phosphatase 2 (PP2A) and PP1 inhibitor withIC50 values of 50 nM and 600 nM, respectively .
|
-
- HY-Y0262BS
-
-
- HY-139597
-
-
- HY-W015114R
-
|
(S)-2-Hydroxyglutaric acid disodium (Standard)
|
Reference Standards
Histone Demethylase
Mitochondrial Metabolism
Endogenous Metabolite
|
Cancer
|
|
L-2-Hydroxyglutaric acid (disodium) (Standard) is the analytical standard of L-2-Hydroxyglutaric acid (disodium). This product is intended for research and analytical applications. L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively .
|
-
- HY-137261
-
|
|
Others
|
Metabolic Disease
|
|
UDP-β-D-glucose disodium is a the stereoisomer of UDP-α-D-glucose. UDP-β-D-glucose disodium is an oligosaccharide that can be used to synthesize glycoproteins and glycolipids. UDP-β-D-glucose disodium can be used as a substrate .
|
-
- HY-N0473A
-
-
- HY-113038AS1
-
|
2-Hydroxyglutarate-d4 disodium; 2-Hydroxyglutaric acid-d4 disodium; 2-Hydroxypentanedioic acid-d4 disodium
|
Histone Demethylase
Endogenous Metabolite
|
Cancer
|
|
α-Hydroxyglutaric acid-d4 (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
|
-
- HY-D0217
-
|
Bromosulfophthalein disodium salt
|
Fluorescent Dye
|
Metabolic Disease
|
|
Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites .
|
-
- HY-113066A
-
|
GDP disodium salt
|
Endogenous Metabolite
Potassium Channel
|
Neurological Disease
Inflammation/Immunology
Cancer
|
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K + channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
|
-
- HY-B0525A
-
|
Sodium carbenicillin
|
Antibiotic
Bacterial
|
Infection
|
|
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .
|
-
- HY-164018A
-
|
|
DNA/RNA Synthesis
|
Infection
|
|
PMEG-DP disodium is a potent DNA polymerase inhibitor (IC50=2.5 μM), especially for DNA polymerase α and δ. PMEG-DP disodium acts as an active metabolite of G-9191, which effectively inhibits the growth of papillomavirus (HPV) -infected cell lines. PMEG-DP disodium can be used in the study of HPV-related diseases .
|
-
- HY-W040147
-
-
- HY-131139
-
|
|
Apoptosis
|
Neurological Disease
Cancer
|
|
Ganglioside GD3 disodium salt is an acidic glycosphingolipid. Ganglioside GD3 disodium salt inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 disodium salt can be used in research about cancer and neurodegenerative diseases .
|
-
- HY-148029
-
|
TAK-676
|
STING
|
Cancer
|
|
Dazostinag disodium (TAK-676) is an agonist of STING, triggering the activation of STING signaling pathway and type I interferons. Dazostinag disodium is also a modulator of immune system, resulting complete regressions and durable memory T-cell immunity. Dazostinag disodium promotes durable IFN-dependent antitumor immunity .
|
-
- HY-113407C
-
|
|
Drug Intermediate
|
Metabolic Disease
|
|
D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
|
-
- HY-153631
-
|
|
Drug Intermediate
|
Inflammation/Immunology
|
|
Sulfo-TAG NHS ester (disodium) is an N-hydroxysuccinimide ester that can be coupled to proteins via primary amine groups. Sulfo-TAG NHS ester (disodium) can be used for antibody labeling .
|
-
- HY-B1141
-
|
NC-503
|
Amyloid-β
|
Others
|
|
Eprodisate disodium (NC-503) is the orally available disodium salt form of Eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
|
-
- HY-113606
-
|
|
Drug Intermediate
|
Metabolic Disease
|
|
Adenosine 5'-phosphosulfate disodium is a metabolism intermediates of sulfur. Adenosine 5'-phosphosulfate disodium can used in study sulfotransferases and sulforeductases in various organisms .
|
-
- HY-106723A
-
|
|
HSP
|
Cancer
|
|
AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90 .
|
-
- HY-B1247A
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
- HY-13781R
-
|
|
Antifolate
Autophagy
Apoptosis
|
Cancer
|
|
Pemetrexed (disodium hemipenta hydrate) (Standard) is the analytical standard of Pemetrexed (disodium hemipenta hydrate). This product is intended for research and analytical applications. Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
|
-
- HY-W740049
-
-
- HY-W115799
-
|
Ethylenediaminetetraacetic acid disodium manganese
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Biochemical Assay Reagents
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Others
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Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B0730R
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Reference Standards
RANKL/RANK
Toll-like Receptor (TLR)
Wnt
β-catenin
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Metabolic Disease
Inflammation/Immunology
Cancer
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Pamidronate (disodium pentahydrate) (Standard) is the analytical standard of Pamidronate (disodium pentahydrate). This product is intended for research and analytical applications. Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
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- HY-N7032
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UDP-D-Glucose disodium
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Endogenous Metabolite
P2Y Receptor
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Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
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Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.
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- HY-W013100
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Cytidine triphosphate disodium; 5'-CTP disodium
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
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Metabolic Disease
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Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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- HY-Z3203S
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- HY-128374R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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D-Glucose 6-phosphate disodium salt (Standard) is the analytical standard of D-Glucose 6-phosphate disodium salt (HY-128374). This product is intended for research and analytical applications. D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6.
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- HY-113407A
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Endogenous Metabolite
FBPase
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Neurological Disease
Metabolic Disease
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D-Fructose 6-phosphate disodium is an endogenous metabolite. D-Fructose 6-phosphate disodium can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia.
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- HY-F0002AR
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Endogenous Metabolite
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Metabolic Disease
Inflammation/Immunology
Cancer
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NADP (disodium salt) (Standard) is the analytical standard of NADP (disodium salt). This product is intended for research and analytical applications. NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
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- HY-137255
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3-Sulfotaurolithocholic acid disodium
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GPR39
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Inflammation/Immunology
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Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 71.6 and 69.4 (absence of Zn 2+) and 9 and 9.6 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
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- HY-W582564
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Ethylenediaminetetraacetic acid copper disodium tetrahydrate
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Biochemical Assay Reagents
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Others
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Cu(Ⅱ)-EDTA disodium tetrahydrate, a typical contaminant in industrial wastewater, is an EDTA-complexed heavy metal. Cu(Ⅱ)-EDTA disodium tetrahydrate can be used in research on the recovery of heavy metal resources from mixed wastewater .
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- HY-160202
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Bacterial
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Infection
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18:1 Cardiolipin disodium is a virulence regulator with two phosphate groups and four acyl chains.18:1 Cardiolipin disodium can be used in the study of the regulation and mechanism of bacterial infection .
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- HY-W115721
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Sodium rhodizonate dibasic
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Biochemical Assay Reagents
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Others
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Rhodizonic acid disodium (Sodium rhodizonate dibasic) can be used as an indicator in the volumetric determination of barium and sulfates. Rhodizonic acid disodium is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-114364
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P2Y Receptor
Endogenous Metabolite
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Infection
Neurological Disease
Metabolic Disease
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UDP-Galactose disodium is a natural agonist of the P2Y14 receptor with an EC50 of 0.67 μM for the hP2Y14 receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major .
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- HY-W013175
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- HY-B0174
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- HY-W300403A
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- HY-138870
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Bacterial
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Infection
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Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Enzyme-IN-3 disodium has antibacterial activity .
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- HY-15928
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p-Nitrophenyl phosphate disodium
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Fluorescent Dye
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Others
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4-Nitrophenyl phosphate (p-Nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
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- HY-131524S
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- HY-143840S
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- HY-143645S
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Isotope-Labeled Compounds
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Others
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Glycochenodeoxycholic acid 3-sulfate-d5 (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium .
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- HY-143017S
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- HY-139614S
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- HY-116022A
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p-Nitrophenyl phosphate disodium hexahydrate
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Biochemical Assay Reagents
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Others
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4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .
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- HY-W879008
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- HY-123065
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- HY-107360
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- HY-21586
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m7GTP disodium
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Nucleoside Antimetabolite/Analog
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Metabolic Disease
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7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor .
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- HY-N2021A
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- HY-133424A
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Fluorescent Dye
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Others
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Trisulfo-Cy3-acid disodium is a derivative of Cy3 (Cyanine3) dye. Trisulfo-Cy3-acid disodium contains three sulfonate ions and has improved water solubility.
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- HY-126304
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Phosphatase
Endogenous Metabolite
ERK
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Metabolic Disease
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β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .
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- HY-N11102A
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Others
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Others
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Thymidine-5'-diphosphate-L-rhamnose disodium is the disodium form of Thymidine-5'-diphosphate-L-rhamnose (HY-N11102). Thymidine-5'-diphosphate-L-rhamnose disodium can be isolated from Occhromonas malhamensis .
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- HY-W009371
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DNA/RNA Synthesis
Endogenous Metabolite
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Metabolic Disease
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D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate disodium is used in the synthesis of nucleotides and nucleic acids .
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- HY-W700989
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- HY-W009162S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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Cytidine 5′-monophosphate- 15N3 (disodium) is the 15N labeled Cytidine 5'-monophosphate disodium . Cytidine 5'-monophosphate (5'-Cytidylic acid) disodium is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate disodium consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .
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- HY-150659S
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- HY-W110914A
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- HY-W713875
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- HY-D2238
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- HY-W879370
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- HY-D1676
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Phosphatase
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Others
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Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
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- HY-D0170
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Biochemical Assay Reagents
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Others
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Ferene disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-108879
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Bacterial
Antibiotic
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Infection
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Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .
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- HY-W015883A
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- HY-B0397A
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Diclofenamide disodium
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Carbonic Anhydrase
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Neurological Disease
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Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research .
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- HY-W011012S
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Isotope-Labeled Compounds
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Others
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Adenosine 5'-monophosphate- 13C (disodium) is a 13C-labeled Adenosine 5'-monophosphate (HY-W011012). Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
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- HY-W011012S1
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Isotope-Labeled Compounds
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Others
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Adenosine 5'-monophosphate-d2 disodium is the deuterium labeled Adenosine 5'-monophosphate (HY-W011012). Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
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- HY-B0730
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RANKL/RANK
Toll-like Receptor (TLR)
Wnt
β-catenin
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Metabolic Disease
Inflammation/Immunology
Cancer
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Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
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- HY-128738
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- HY-152903S
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- HY-B1657AR
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Reference Standards
Sodium Channel
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Neurological Disease
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Fosphenytoin (disodium) (Standard) is the analytical standard of Fosphenytoin (disodium). This product is intended for research and analytical applications. Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
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- HY-130116A
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STING
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Cancer
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IACS-8779 disodium is a highly potent stimulator of interferon genes (STING) agonist with robust systemic antitumor efficacy. IACS-8779 disodium shows robust activation of the STING pathway in vitro and a superior systemic anti-tumor response in the B16 murine model of melanoma .
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- HY-114364S
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- HY-W008940
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Cytidine diphosphate disodium
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Endogenous Metabolite
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Metabolic Disease
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Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
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- HY-W127778
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Pentacyanoamine ferrate ammonium disodium
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Biochemical Assay Reagents
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Others
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Ammonium disodium pentacyanoammineferrate(II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-D0199S
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Endogenous Metabolite
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Others
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Adenosine- 15N5 5′-diphosphate (disodium salt) is the 15N labeled Adenosine 5'-diphosphate disodium salt .
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- HY-139610S
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- HY-W011012S2
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- HY-133953A
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Drug Intermediate
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Others
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9-Oxoheptadecanedioic acid (Compound 46) disodium is a precursor of Civetone used for labeling proteins .
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- HY-D0855A
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Biochemical Assay Reagents
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Others
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ADA (disodium) is a buffer salt derived from ADA (adenosine deaminase) and is widely used in biochemical research, especially in the preparation of enzyme buffers.
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- HY-W015114
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(S)-2-Hydroxyglutaric acid disodium
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Histone Demethylase
Mitochondrial Metabolism
Endogenous Metabolite
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Cancer
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L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively .
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- HY-13038BR
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Syk
FLT3
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Inflammation/Immunology
Cancer
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Fostamatinib (disodium hexahydrate) (Standard) is the analytical standard of Fostamatinib (disodium hexahydrate). This product is intended for research and analytical applications. Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
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- HY-W015883AS
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- HY-107921
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EDTA calcium disodium salt,98%; Adsorbonac,98%
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Biochemical Assay Reagents
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Others
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EDTA Calcium disodium, 98% (EDTA calcium disodium salt, 98%; Adsorbonac, 98%) is a chelating agent for calcium and other metal ions, preventing them from participating in chemical reactions. It can effectively remove metal ions from solutions, preventing them from interfering with experimental processes.
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- HY-B2097
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YM 175; Bisphonal
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Farnesyl Transferase
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Metabolic Disease
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Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (Ki=57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC50=64 μM). Incadronate disodium has the potential for malignant tumors research .
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- HY-N7032S
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UDP-D-Glucose-13C disodium
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Isotope-Labeled Compounds
Endogenous Metabolite
P2Y Receptor
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Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
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Uridine 5′-diphosphoglucose- 13C (UDP-D-Glucose- 13C) disodium is the 13C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032) . Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .
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- HY-134269A
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7-deaza-8-bromo-cADPR disodium; 7-deaza-8-bromo-cyclic ADP ribose disodium
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Calcium Channel
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Neurological Disease
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8-Br-7-CH-cADPR disodium (7-Deaza-8-bromo-cADPR) is a potent cADPR antagonist. 8-Br-7-CH-cADPR disodium shows partial inhibition of calcium elevation caused by sTIR dimerization. 8-Br-7-CH-cADPR disodium significantly decreases Paclitaxel (HY-B0015)-induced axon degeneration .
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- HY-17449
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CA 4DP; CA 4P; Combretastatin A4 disodium phosphate
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Microtubule/Tubulin
Apoptosis
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Cancer
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Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin disodium is the Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis .
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- HY-W879228
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Fluorescent Dye
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Others
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Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .
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- HY-B1657AS
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Isotope-Labeled Compounds
Sodium Channel
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Neurological Disease
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Fosphenytoin-d10 (disodium) is deuterium labeled Fosphenytoin (disodium). Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
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- HY-D0886
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Phosphatase
Endogenous Metabolite
ERK
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Metabolic Disease
Cancer
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β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .
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- HY-D0850
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Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate
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Phosphatase
Endogenous Metabolite
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Cardiovascular Disease
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Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications .
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- HY-113407CS
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Isotope-Labeled Compounds
Drug Intermediate
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Metabolic Disease
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D-Fructose-6-phosphate disodium monohydrate- 13C6 is the 13C-labeled D-Fructose-6-phosphate disodium monohydrate (HY-113407C). D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
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- HY-134318B
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DNA/RNA Synthesis
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Others
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8-Azido-ADP (disodium) is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP (disodium) causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP (disodium) inhibits the normal state 4 → 3 transitions of mitochondrial respiration induced by ADP . 8-Azido-ADP (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-B0012AR
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CGP 23339A (Standard)
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RANKL/RANK
Toll-like Receptor (TLR)
Wnt
β-catenin
Reference Standards
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Metabolic Disease
Inflammation/Immunology
Cancer
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Pamidronate disodium (Standard) is the analytical standard of Pamidronate disodium. Pamidronate disodium (CGP 23339A), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
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- HY-113066AR
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Endogenous Metabolite
Potassium Channel
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Neurological Disease
Inflammation/Immunology
Cancer
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Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
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- HY-A0213A
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Tiludronic acid disodium
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Proton Pump
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Inflammation/Immunology
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Tiludronate (Tiludronic Acid) disodium, an orally active bisphosphonate, can act an osteoregulator. Tiludronate is used for the research of the metabolic bone disorders. Tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase. Antiresorptive and anti-inflammatory properties .
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- HY-145934A
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OGT
Biochemical Assay Reagents
Glycosidase
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Metabolic Disease
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UDP-GlcNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GlcNAc (HY-112174). UDP-GlcNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GlcNAc (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1848
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Fluorescent Dye
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Others
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Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-129963
-
-
- HY-D0505A
-
|
Acid Red 87
|
Fluorescent Dye
|
Others
|
|
Eosin Y disodium (Acid Red 87) is a soluble acid red dye molecule. Eosin Y disodium has a wide application in organic synthesis as a photoredox catalyst .
|
-
- HY-W151206
-
|
|
Fluorescent Dye
|
Others
|
|
Hydroxy naphthol blue disodium, an azo dye, is a metal indicator for calcium and a colorimetric reagent for alkaline earth metal ions ( λmax = 650 nm). In the pH range between 12 and 13, the solution of the indicator is reddish pink in the presence of calcium ion and to deep blue in the presence of disodium EDTA .
|
-
- HY-112253A
-
|
|
Endogenous Metabolite
|
Others
|
|
D-Fructose 1-phosphate disodium salt is a derivative of fructose. It is an important intermediate of glucose metabolism.
|
-
- HY-113128S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
sn-Glycerol 3-phosphate- 13C3 disodium is the 13C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .
|
-
- HY-157917
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .
|
-
- HY-128747R
-
|
|
Reference Standards
Endogenous Metabolite
|
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
|
|
α-D-Glucose-1-phosphate disodium (Standard) is the analytical standard of α-D-Glucose-1-phosphate disodium (HY-128747). This product is intended for research and analytical applications.
α-D-Glucose-1-phosphate disodium is used as a starting material for synthesis of glucuronic acid. α-D-Glucose-1-phosphate disodium can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive agent, and as a circulatory system therapy element.
|
-
- HY-W615108B
-
|
NMNH disodium
|
Endogenous Metabolite
|
Cancer
|
|
β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is an orally active reduced version of β-Nicotinamide mononucleotide (HY-F0004). β-Nicotinamide mononucleotide, reduced form disodium can significantly increase the levels of NAD + and NADH, inhibit glycolysis, the tricarboxylic acid cycle, and cell growth, with its effects being dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT) .
|
-
- HY-W744986
-
|
(2S)-2-Hydroxyglutaric acid-d5 disodium
|
Isotope-Labeled Compounds
Histone Demethylase
Mitochondrial Metabolism
Endogenous Metabolite
|
Cancer
|
|
L-2-Hydroxyglutaric acid-d5 disodium ((2S)-2-Hydroxyglutaric acid-d5 disodium) is the deuterium labeled L-2-Hydroxyglutaric acid disodium (HY-W015114). L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively .
|
-
- HY-D0850R
-
|
Sodium tartrate dibasic dihydrate (Standard); Sodium tartrate dihydrate (Standard)
|
Reference Standards
Phosphatase
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Tartaric acid (disodium dihydrate) (Standard) is the analytical standard of Tartaric acid (disodium dihydrate). This product is intended for research and analytical applications. Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications [4].
|
-
- HY-W793605
-
-
- HY-B1654A
-
|
FAD disodium salt; FAD-Na2
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
|
-
- HY-W105272
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
|
-
- HY-W134005
-
|
Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate
|
Phosphatase
|
Others
|
|
Mg(Ⅱ)-EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (Km=0.9 μM). Mg(Ⅱ)-EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg 2+, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis .
|
-
- HY-129834
-
|
|
Drug Metabolite
|
Metabolic Disease
|
|
Bilirubin Conjugate disodium is a ditaurate derivative of Bilirubin. Bilirubin, a major end product of heme breakdown, is an important constituent of bile .
|
-
- HY-128695
-
|
|
Drug Derivative
|
Inflammation/Immunology
|
|
Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid (HY-128695) with anti-inflammatory and potential anti-ulcer activities .
|
-
- HY-A0119
-
|
Sodium nitroprusside dihydrate; Sodium Nitroferricyanide(III) Dihydrate
|
Autophagy
|
Cardiovascular Disease
Cancer
|
|
Nitroprusside disodium dehydrate (Sodium nitroprusside dihydrate) is a vasodilator that available for the research of acute hypertension, heart failure. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model .
|
-
- HY-W766913
-
-
- HY-W011061
-
-
- HY-137243
-
-
- HY-113407CR
-
|
|
Reference Standards
Drug Intermediate
|
Metabolic Disease
|
|
D-Fructose-6-phosphate disodium monohydrate (Standard) is the analytical standard of D-Fructose-6-phosphate disodium monohydrate. D-Fructose-6-phosphate is an intermediate of Glycolysis. D-Fructose-6-phosphate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
|
-
- HY-106139A
-
|
TBC-1269Z
|
P-selectin
|
Inflammation/Immunology
|
|
Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose disodium has anti-inflammatory effects .
|
-
- HY-W601362
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-galactosamine-6-phosphate disodium is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate disodium can be hydrolyze by NagA .
|
-
- HY-139793
-
|
|
OGT
Endogenous Metabolite
|
Metabolic Disease
|
|
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .
|
-
- HY-13781
-
|
LY231514 disodium hemipenta hydrate
|
Antifolate
Autophagy
Apoptosis
|
Cancer
|
|
Pemetrexed disodium hemipenta hydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
|
-
- HY-10820B
-
|
LY231514 disodium heptahydrate
|
Antifolate
Autophagy
|
Cancer
|
|
Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
|
-
- HY-128374
-
-
- HY-B0012A
-
|
CGP 23339A
|
RANKL/RANK
Toll-like Receptor (TLR)
Wnt
β-catenin
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Pamidronate disodium (CGP 23339A), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
|
-
- HY-160199A
-
|
|
Drug Derivative
|
Others
|
|
3'-L-histidyl-AMP (disodium) is applicable for nucleoside modification (DNA, RNA) .
|
-
- HY-W339545A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
α-Ketoglutaric acid disodium hydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium hydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties .
|
-
- HY-144085S
-
-
- HY-N7389B
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM) .
|
-
- HY-W127776
-
|
Ethylenediaminetetraacetic acid zinc disodium tetrahydrate
|
Biochemical Assay Reagents
|
Others
|
|
Zn(Ⅱ)-EDTA (Ethylenediaminetetraacetic acid zinc) disodium tetrahydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-N7032S1
-
|
UDP-D-Glucose-13C6 disodium
|
Isotope-Labeled Compounds
Endogenous Metabolite
P2Y Receptor
|
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
|
|
Uridine 5′-diphosphoglucose- 13C6 (UDP-D-Glucose- 13C6) disodium is the 13C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032) . Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .
|
-
- HY-137942
-
|
α-Naphthyl phosphate disodium salt, 98%
|
Biochemical Assay Reagents
|
Others
|
|
1-Naphthyl phosphate disodium salt, 98% is a histochemical substrate for acidic and alkaline phosphatases, and can also be used as a substrate for measuring prostatic acid phosphatase.
|
-
- HY-124329A
-
|
|
ADC Linker
|
Cancer
|
|
BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145934
-
|
UDP-N-azidoacetylgalactosamine disodium
|
Biochemical Assay Reagents
OGT
Glycosidase
|
Metabolic Disease
|
|
UDP-GalNAz (UDP-N-azidoacetylgalactosamine) disodium is the analogue of UDP-GalNAc (HY-114365). UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134242
-
|
6-Thioguanosine monophosphate disodium; 6-Thio-GMP disodium
|
Drug Metabolite
|
Inflammation/Immunology
|
|
6-T-5'-GMP disodium is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, azathioprine (HY-B0256) .
|
-
- HY-103233
-
|
FG 9041 disodium salt
|
iGluR
|
Cancer
|
|
DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) .
|
-
- HY-130767A
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Naphthol AS-TR Phosphate disodium is a water-soluble dye commonly used as an enzymatic substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate disodium has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase, forming a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.
|
-
- HY-128747
-
-
- HY-128747A
-
-
- HY-W011142
-
|
dUMP disodium
|
Endogenous Metabolite
|
Infection
Metabolic Disease
|
|
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
|
-
- HY-151267A
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-25 (Compound CP026) disodium is a potent SARS-CoV-2 spike pseudoparticle transduction inhibitor with an IC50 of 1.6 μM. SARS-CoV-2-IN-25 disodium inhibits enveloped viruses and liposomes .
|
-
- HY-111926
-
|
|
Phosphorylase
|
Metabolic Disease
|
|
N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 µM . N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor .
|
-
- HY-164903A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
UDP-D-GalNAlk disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W010832
-
-
- HY-151269A
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-23 disodium is a two-armed diphosphate ester and medium length molecular tweezers. SARS-CoV-2-IN-23 disodium exhibits antiviral activity with IC50s of 8.2 μM and 2.6 μM against SARS-CoV-2 activity and the spike pseudoparticle transduction, respectively. SARS-CoV-2-IN-23 disodium induces liposomal membrane disruption with an EC50 value of 4.4 μM .
|
-
- HY-151276A
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-29 disodium is a two-armed diphosphate ester with benzene system and molecular tweezers. SARS-CoV-2-IN-29 disodium exhibits antiviral activity with IC50s of 1.5 μM and 1.6 μM against SARS-CoV-2 activity and the spike pseudoparticle transduction, respectively. SARS-CoV-2-IN-29 disodium induces liposomal membrane disruption with an EC50 value of 3.0 μM .
|
-
- HY-151274A
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-28 disodium is a two-armed diphosphate ester with C7 alkyl and molecular tweezers with extended length. SARS-CoV-2-IN-28 disodium exhibits antiviral activity with IC50s of 0.4 μM and 1.0 μM against SARS-CoV-2 activity and the spike pseudoparticle transduction, respectively. SARS-CoV-2-IN-28 disodium induces liposomal membrane disruption with an EC50 value of 4.4 μM .
|
-
- HY-151271A
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-27 disodium is a two-armed diphosphate ester with C6 alkyl and molecular tweezers with extended length. SARS-CoV-2-IN-27 disodium exhibits antiviral activity with IC50s of 1.0 μM and 1.7 μM against SARS-CoV-2 activity and the spike pseudoparticle transduction, respectively. SARS-CoV-2-IN-27 disodium induces liposomal membrane disruption with an EC50 value of 6.5 μM .
|
-
- HY-151278A
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-30 disodium is a two-armed diphosphate ester with benzene system and molecular tweezers. SARS-CoV-2-IN-30 disodium exhibits antiviral activity with IC50s of 0.6 μM and 6.9 μM against SARS-CoV-2 activity and the spike pseudoparticle transduction, respectively. SARS-CoV-2-IN-30 disodium induces liposomal membrane disruption with an EC50 value of 6.9 μM .
|
-
- HY-W802699
-
|
|
Biochemical Assay Reagents
|
Others
|
|
α-Ketoglutaric acid disodium dihydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium dihydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties .
|
-
- HY-W145626
-
|
beta-D-Glucopyranose 1-phosphate disodium salt
|
Biochemical Assay Reagents
|
Others
|
|
β-D-Glucopyranose 1-Phosphate Disodium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W133934A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
EDTA magnesium disodium, 99% is a chelating agent with the ability to effectively bind metal ions (including calcium, magnesium, and iron) and remove them from solution.
|
-
- HY-110385
-
|
Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium
|
STING
Endogenous Metabolite
|
Inflammation/Immunology
|
|
cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
|
-
- HY-100747A
-
|
|
CD73
|
Cancer
|
|
PSB-12379 disodium, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human) .
|
-
- HY-130547
-
|
|
ADC Linker
|
Cancer
|
|
BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-16182A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Ecamsule disodium is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression .
|
-
- HY-131475A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Naphthol AS-BI phosphate (disodium hydrate) is used as a substrate for determining the activity of both alkaline and acidic phosphatases; it can also be used to measure the activity of individual cell acid phosphatase.
|
-
- HY-D0885A
-
|
Creatine phosphate disodium tetrahydrate; Creatinephosphoric acid disodium tetrahydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Phosphocreatine disodium tetrahydrate, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction .
|
-
- HY-141535A
-
|
|
Interleukin Related
|
Infection
Inflammation/Immunology
|
|
IL-17 modulator 1 (disodium) is an orally active, highly efficacious IL-17 modulator extracted from patent WO 2020127685. IL-17 modulator 1 (disodium) can be used for the research of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis .
|
-
- HY-W590551A
-
-
- HY-W105272S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2′-Deoxyadenosine 5′-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2′-Deoxyadenosine 5′-monophosphate disodium . 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
|
-
- HY-W010759
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP .
|
-
- HY-W250156
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Acetylpyridine adenine dinucleotide (disodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-147063
-
|
|
Endogenous Metabolite
|
Others
|
|
N-acetyl-α-d-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, is a key intermediate in the biosynthesis of N-linked glycoproteins. N-acetyl-α-d-glucosamine 1-phosphate disodium is a metabolic precursor of the bacterial cell-wall components teichoic acid and mureine .
|
-
- HY-W250303
-
|
Hydroxybutanedioic acid disodium salt; E 296 disodium salt
|
Biochemical Assay Reagents
|
Others
|
|
Sodium DL-Malate is an organic compound commonly used as a food additive, buffer and nutritional supplement. It contains sodium and malic acid. Malic acid disodium salt has several properties suitable for these applications, including the ability to enhance food flavor, improve texture and regulate acidity. Additionally, it can be used as a dietary supplement due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance.
|
-
- HY-W243460
-
|
|
Biochemical Assay Reagents
|
Others
|
|
EDTA copper(II) disodium salt, 97% can be used to eliminate the inhibition of enzyme-catalyzed reactions caused by trace heavy metals.
|
-
- HY-B1175R
-
|
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
|
(2S,5R,6R)-Ticarcillin disodium (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin disodium. This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is a semisynthetic antibiotic with bactericidal activities. (2S,5R,6R)-Ticarcillin disodium is the (2S,5R,6R)-enantiomer of Ticarcillin (HY-139805).
|
-
- HY-126304A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Glycerophosphoric acid (disodium salt hydrate) (α and β mixture) is a complex contains α and β Glycerophosphoric acid isomers.
|
-
- HY-108244
-
|
|
Interleukin Related
STAT
|
Inflammation/Immunology
Cancer
|
|
Balsalazide disodium is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway .
|
-
- HY-136072A
-
|
(1R,2S)-QPX7728 disodium
|
Drug Derivative
|
Others
|
|
(1R,2S)-Xeruborbactam ((1R,2S)-QPX7728) disodium is a boronic acid derivative .
|
-
- HY-13615A
-
|
|
Fluorescent Dye
Folate Receptor (FR)
|
Cancer
|
|
EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .
|
-
- HY-13038B
-
|
R788 disodium hexahydrate
|
Syk
FLT3
|
Inflammation/Immunology
Cancer
|
|
Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
|
-
- HY-W127712
-
-
- HY-141931S1
-
-
- HY-W105310A
-
|
Nacr
|
Biochemical Assay Reagents
|
Others
|
|
Croconic acid (disodium) (Nacr) can promote cell growth and proliferation by enhancing the expression of genes associated with lysine crotonylation (Kcr) modification. Croconic acid holds potential for improving somatic cell nuclear transfer (SCNT) efficiency and optimizing cell culture conditions research
|
-
- HY-W013175S2
-
|
5'-Uridylic acid-13C9,15N2 disodium
|
Isotope-Labeled Compounds
Endogenous Metabolite
Cholinesterase (ChE)
Potassium Channel
Apoptosis
|
Cardiovascular Disease
Metabolic Disease
|
|
Uridine 5'-monophosphate- 13C9, 15N2 disodium is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt (HY-W013175). Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
|
-
- HY-D1867
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-137896
-
|
|
Fluorescent Dye
|
Others
|
|
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium is a fluorescent dye. 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium can be used to demonstrate retrograde axonal transport to label secondary antibodies and as a fluorescent whole cell stain .
|
-
- HY-147061
-
|
|
Endogenous Metabolite
|
Others
|
|
2-Deoxyribose 5-phosphate disodium is a substrate of 2-deoxyribose-5-phosphate aldolase (DERA). DERA belongs to the class I aldolases and catalyzes the reversible aldol condensation reaction without any cofactors .
|
-
- HY-137255S
-
-
- HY-B1175
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
(2S,5R,6R)-Ticarcillin disodium is a semisynthetic antibiotic with bactericidal activities. (2S,5R,6R)-Ticarcillin disodium is the (2S,5R,6R)-enantiomer of Ticarcillin (HY-139805) .
|
-
- HY-B0712S
-
|
Ro 13-9904-d3 disodium
|
Bacterial
Antibiotic
|
Infection
|
|
Ceftriaxone-d3 (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics .
|
-
- HY-W009371C
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Ribose 5-phosphate disodium dihydrate is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids .
|
-
- HY-B1433S
-
-
- HY-174295
-
|
|
Drug Derivative
|
Others
|
|
Guanine nucleotide imidazolide intermediate (Compound 19e) disodium is a guanine nucleotide derivative that can be used to synthesize modified RNA .
|
-
- HY-141719S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
N-Acetyl-S-(3-carboxy-2-propyl)-L-cysteine-d3 disodium is the deuterium labeled N-Acetyl-S-(3-carboxy-2-propyl)-L-cysteine disodium .
|
-
- HY-114365
-
|
UDP-N-acetyl-D-galactosamine disodium
|
Endogenous Metabolite
|
Metabolic Disease
|
|
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate of EpsC115. EpsC115 is an exopolymeric substances (EPS) N-terminal deletion mutant with the residue 1-115 deletion. UDP-GalNAc UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor .
|
-
- HY-W127790
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent for iron detection, with a wavelength of 535 nm for iron complex. It can be used for iron determination in aqueous solution systems without the need for extraction solvents. BPS can serve as a precursor to prepare Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) complex and ruthenium(II) tris(bathophenanthrolinedisulfonate), or participate in the catalytic oxidation of 2-hexanol by forming water-soluble complexes with palladium .
|
-
- HY-124329AS
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
BS3 Crosslinker-d4 (disodium) is the deuterium labeled BS3 Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-N8515C
-
|
UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium
|
Endogenous Metabolite
|
Infection
Others
|
|
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .
|
-
- HY-18756A
-
|
|
SHP2
SHP1
Phosphatase
Apoptosis
|
Cancer
|
|
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively . NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26) .
|
-
- HY-W854355
-
|
|
Biochemical Assay Reagents
|
Others
|
|
D-Mannose-6-phosphate (disodium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W747072
-
|
3-Sulfocholyl Taurine; TCA3S
|
Drug Metabolite
|
Metabolic Disease
|
|
3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine; TCA3S) is a metabolite of the conjugated bile acid taurocholic acid. Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL.
|
-
- HY-W127347
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,2-Dioleoyl-sn-glycero-3-phosphoric acid disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-15027S3
-
|
Mesalamine-d3 disodium; 5-ASA-d3 disodium; Mesalazine-d3 disodium
|
PPAR
NF-κB
Endogenous Metabolite
PAK
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
5-Aminosalicylic acid-d3 disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
|
-
- HY-141945S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Taurochenodeoxycholic acid-3-o-glucuronide-d4 (disodium) is the deuterium labeled Taurochenodeoxycholic acid-3-o-glucuronide .
|
-
- HY-D0206
-
|
|
Fluorescent Dye
|
Others
|
|
Chromotropic acid disodium is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W010737
-
|
5'-GTP disodium salt
|
Endogenous Metabolite
MicroRNA
|
Metabolic Disease
|
|
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
|
-
- HY-128738S
-
|
TMP-13C10,15N2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Thymidine-5'-monophosphate- 13C10, 15N2 (disodium) is the 13C and 15N labeled Thymidine-5'-monophosphate disodium salt . Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
|
-
- HY-130547S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
BS2G Crosslinker-d4 (disodium) is the deuterium labeled BS2G Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-W747597
-
|
Disialoganglioside GD1b; Ganglioside C1; Ganglioside G2
|
Endogenous Metabolite
|
Cancer
|
|
Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) is an acidic glycosphingolipid containing two sialic acid residues linked to an internal galactose unit. Ganglioside GD1b Disodium Salt tightly packs with cholesterol to form lipid microdomains that modulate intracellular and intercellular signaling events. Concentrations of Ganglioside GD1b Disodium Salt (Bovine Brain) in the human brain increase with age and are positively correlated with pilocytic astrocytoma tumor grade. Ganglioside GD1b Disodium Salt has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.
|
-
- HY-W768574
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Bisphenol A Bissulfate Disodium Salt- 13C12 is the 13C-labeled Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate (2:1) (HY-W587516).
|
-
- HY-N7389A
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
GDP-D-mannose disodium contains GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM) .
|
-
- HY-145538
-
|
5'-Deoxyguanylic acid disodium hydrate
|
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxyguanosine 5'-monophosphate (5'-Deoxyguanylic acid; dGMP) disodium hydrate is an oxidizable target of the photosensitizer pterin (PT) and can be used to evaluate the photosensitizing properties of biopterins (such as Bip, Fop and Cap) . Pterin causes a photosensitive reaction of dGMP under UV-A radiation, causing damage to DNA molecules. There are two main mechanisms for the photosensitive oxidation of purine nucleotides by pterin in vitro: one is the hydrogen abstraction reaction of electron transfer from dGMP to the triplet excited state of pterin (type I mechanism), and the other is the interaction between dGMP and pterin. The reaction produces singlet molecular oxygen (1O2) (Type II mechanism) .
|
-
- HY-112537S1
-
-
- HY-139409A
-
|
|
Drug Derivative
|
Metabolic Disease
|
|
2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
|
-
- HY-W779800
-
-
- HY-W013159S
-
|
dGMP-13C10,15N5
|
Isotope-Labeled Compounds
Endogenous Metabolite
Nucleoside Antimetabolite/Analog
|
Metabolic Disease
|
|
2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (dGMP- 13C10, 15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
|
-
- HY-D1851
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-137672A
-
|
2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate
|
Phosphodiesterase (PDE)
Calcium Channel
|
Neurological Disease
|
|
2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme abundant in myelin. It has been used in a coupled enzyme assay to quantify CNP activity. 2',3'-Cyclic NADP disodium (5 μM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria.
|
-
- HY-W034953
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.
|
-
- HY-125818S1
-
|
|
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Cytidine-5′-triphosphate-d14 disodium is the deuterium labeled Cytidine-5'-triphosphate . Cytidine 5′-triphosphate (Cytidine triphosphate;5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
|
-
- HY-113044R
-
|
UDP-D-Glucose (Standard)
|
Reference Standards
Endogenous Metabolite
P2Y Receptor
|
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
|
|
Uridine 5′-diphosphoglucose (Standard) (UDP-D-Glucose (Standard)) is the analytical standard of Uridine 5′-diphosphoglucose (HY-113044). This product is intended for research and analytical applications. Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.
|
-
- HY-113044
-
|
UDP-D-Glucose
|
Endogenous Metabolite
P2Y Receptor
|
Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
|
|
Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .
|
-
- HY-A0181BS
-
|
AMP-13C10,15N5 disodium
|
Isotope-Labeled Compounds
Endogenous Metabolite
Adenosine Receptor
HSV
|
Infection
Metabolic Disease
|
|
Adenosine monophosphate- 13C10, 15N5 (AMP- 13C10, 15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
|
-
- HY-W008646R
-
|
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
|
-
- HY-W766835
-
|
Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate-d6 (2:1)
|
Isotope-Labeled Compounds
|
Others
|
|
Bisphenol A bissulfate-d6 (disodium salt) (Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate-d6 (2:1)) is the deuterium labeled Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate (2:1) (HY-W587516).
|
-
- HY-138247R
-
|
EX-A4764 (Standard); UUN51204 (Standard)
|
Beta-lactamase
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
ATP (disodium salt) (Standard) is the analytical standard of ATP (disodium salt). This product is intended for research and analytical applications. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-13570CS
-
|
|
Apoptosis
Glucocorticoid Receptor
Isotope-Labeled Compounds
|
Others
|
|
Betamethasone 21-phosphate-d5 is the deuterium labeled Betamethasone disodium phosphate. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids .
|
-
- HY-108971R
-
|
|
Antibiotic
Reference Standards
Bacterial
|
Infection
|
|
Uridine 5'-monophosphate (disodium salt) (Standard) is the analytical standard of Uridine 5'-monophosphate (disodium salt). This product is intended for research and analytical applications. Uridine 5'-monophosphate disodium salt is component used for RNA synthesis.
|
-
- HY-135359R
-
|
|
Drug Metabolite
Reference Standards
|
Neurological Disease
|
|
Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
- HY-108213AR
-
|
5'-IMP disodiumhydrate(1:2:X) (Standard); IMP disodiumhydrate(1:2:X) (Standard); Inosine 5'-(dihydrogen phosphate) disodiumhydrate(1:2:X) (Standard)
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
Inosinic acid (disodium)(hydrate)(1:2:X) (Standard) is the analytical standard of Inosinic acid (disodium)(hydrate)(1:2:X). This product is intended for research and analytical applications. Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
|
-
- HY-100196AR
-
|
PQQ disodium salt (Standard); Methoxatin disodium salt (Standard)
|
Reference Standards
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Triazophos (Standard) is the analytical standard of Triazophos. This product is intended for research and analytical applications. Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.
|
-
- HY-125818C
-
|
Cytidine triphosphate disodium hydrate; 5'-CTP disodium hydrate
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Infection
Cancer
|
|
Cytidine 5′-triphosphate is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
|
-
- HY-109000A
-
|
Debio 1450 disodium; AFN-1720 disodium
|
Bacterial
|
Infection
|
|
Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci .
|
-
- HY-12326A
-
|
Cyclic diadenylate disodium; Cyclic-di-AMP disodium
|
STING
Bacterial
Endogenous Metabolite
|
Inflammation/Immunology
|
|
c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .
|
-
- HY-108932A
-
|
Gemcitabine 5′-phosphate disodium
|
Apoptosis
|
Cancer
|
|
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .
|
-
- HY-113038AR
-
|
2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard)
|
Reference Standards
Histone Demethylase
Endogenous Metabolite
|
Cancer
|
|
Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside . Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years .
|
-
- HY-108213A
-
|
5'-IMP disodiumhydrate(1:2:X); IMP disodiumhydrate(1:2:X); Inosine 5'-(dihydrogen phosphate) disodiumhydrate(1:2:X)
|
Endogenous Metabolite
|
Others
|
|
Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
|
-
- HY-D1160
-
-
- HY-136830
-
|
Adenosine-5'-diphosphoglucose disodium
|
Biochemical Assay Reagents
|
Others
|
|
ADP-Glucose disodiumIs an immediate precursor for the biosynthesis of storage polysaccharides in plants, green algae and cyanobacteria, and structural polysaccharides in some bacteria, by the addition of glucose. It is used to produce amylose, amylopectin, starch and other polysaccharides by amylose synthase or starch synthase in plastids. ADPGUsually produced in plastids, although it can be biosynthesized in the cytoplasm of some grasses and imported into plastids by membrane-bound transporters .
|
-
- HY-138227A
-
|
3′-dADP disodium
|
DNA/RNA Synthesis
|
Others
|
|
3′-Deoxyadenosine 5′-diphosphate (3′-dADP) disodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.
|
-
- HY-W127640
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Phosphocholine Chloride Sodium Salt is an organic compound containing phosphate, choline and chloride ions. It is commonly used to prepare cell membranes and liposomes for drug delivery systems. Phosphocholine Chloride Sodium Salt has various applications in the pharmaceutical industry, especially as a stabilizer and surfactant. In addition, it is used as an emulsifier and conditioning agent in the manufacture of cosmetic and personal care products.
|
-
- HY-B1657A
-
|
|
Sodium Channel
|
Neurological Disease
|
|
Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
|
-
- HY-W011271
-
|
1,4-Piperazinediethanesulfonic acid monosodium
|
Biochemical Assay Reagents
|
Others
|
|
PIPES (1,4-Piperazinediethanesulfonic acid) monosodium is a pH buffer that can be mixed with another disodium salt form of PIPES. By changing the ratio and total amount of the PIPES monosodium and disodium buffers, the pH and ionic strength of the medium can be changed .
|
-
- HY-W776843
-
-
- HY-N2021AR
-
-
- HY-W096124
-
-
- HY-W704805
-
|
|
Isotope-Labeled Compounds
Histone Demethylase
Endogenous Metabolite
|
Cancer
|
|
Sodium 2-hydroxypentanedioate-2,3,3-d3 is the deuterium labeled α-Hydroxyglutaric acid disodium (HY-113038A). α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
|
-
- HY-B1829
-
|
Dexamethasone 21-phosphate
|
Glucocorticoid Receptor
|
Others
|
|
Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a biologically inactive compound which undergoes dephosphorylation by intra-erythrocyte enzymes. The active metabolite, Dexamethasone, is then released into the circulation by simple passive diffusion through cell membranes. Dexamethasone phosphate disodium-encapsulated erythrocyte has the potential for steroid-dependent ulcerative colitis research .
|
-
- HY-110382S
-
|
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguaylate, 13C20,15N10-3’,5’-Cyclic diguaylic Acid
|
Isotope-Labeled Compounds
Endogenous Metabolite
STING
|
Cancer
|
|
13C20, 15N10-Cyclic di-GMP ( 13C20, 15N10-c-di-GMP) is 13C and 15N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .
|
-
- HY-W587911
-
-
- HY-B0667A
-
|
Balsalazide disodium dihydrate
|
Interleukin Related
STAT
|
Inflammation/Immunology
Cancer
|
|
Balsalazide sodium hydrate is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway .
|
-
- HY-107579R
-
|
AY 25712 (Standard)
|
Reference Standards
GPR109A
|
Cardiovascular Disease
|
|
(2S,5R,6R)-Ticarcillin (disodium) (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin (disodium). This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
|
-
- HY-N11102
-
|
|
Others
|
Others
|
|
Thymidine-5'-diphosphate-L-rhamnose disodium can be isolated from Occhromonas malhamensis .
|
-
- HY-A0213AS
-
|
Tiludronic acid-d5 sodium
|
Isotope-Labeled Compounds
Proton Pump
|
Inflammation/Immunology
|
|
Tiludronate-d5 (sodium)mis the deuterium labeled Tiludronate disodium. Tiludronate (Tiludronic Acid) disodium, an orally active bisphosphonate, can act an osteoregulator. Tiludronate is used for the research of the metabolic bone disorders. Tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase. Antiresorptive and anti-inflammatory properties .
|
-
- HY-U00148
-
-
- HY-147061R
-
|
|
Endogenous Metabolite
Reference Standards
|
Others
|
|
2-Hydroxybenzimidazole (Standard) is the analytical standard of 2-Hydroxybenzimidazole. This product is intended for research and analytical applications. 2-Hydroxybenzimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B1829R
-
|
Dexamethasone 21-phosphate (Standard)
|
Glucocorticoid Receptor
Reference Standards
|
Others
|
|
Dexamethasone phosphate (Standard) is the analytical standard of Dexamethasone phosphate. This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a biologically inactive compound which undergoes dephosphorylation by intra-erythrocyte enzymes. The active metabolite, Dexamethasone, is then released into the circulation by simple passive diffusion through cell membranes. Dexamethasone phosphate disodium-encapsulated erythrocyte has the potential for steroid-dependent ulcerative colitis research .
|
-
- HY-164903
-
|
|
Biochemical Assay Reagents
|
Others
|
|
UDP-D-GalNAlk disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-16344
-
-
- HY-W105272R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical applications. Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM . Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .
|
-
- HY-B0961
-
|
Mercury dibromofluorescein disodium salt; ZP1
|
Flavivirus
Proteasome
|
Others
|
|
Merbromin is a mixed inhibitor of the 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2, with an IC50 of 2.7 μM. Merbromin effectively inhibits the replication of the Zika virus (ZIKV) and shows anti-ZIKV activity by inhibiting ZIKVpro. Merbromin can also be used as a topical disinfectant for cuts and scrapes, and it serves as a biological dye .
|
-
- HY-W013724S
-
-
- HY-N2417
-
|
|
Bacterial
|
Infection
|
|
Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects .
|
-
- HY-147063R
-
|
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
|
-
- HY-157367
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bismuth Sulfite Agar Medium can be used for selective isolation and culture of Salmonella. Bismuth Sulfite Agar Medium ingredients include tryptone, peptone, beef powder, ferrous sulfate, bismuth sulfite, disodium hydrogen phosphate, glucose, brilliant green, agar .
|
-
- HY-113038AS
-
|
2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 sodium; 2-Hydroxypentanedioic acid-13C5 disodium
|
Histone Demethylase
Endogenous Metabolite
|
Cancer
|
|
α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
|
-
- HY-W748361
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3(Me)COOH sodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Trisulfo-Cy3-acid disodium contains sulfonate ions and has improved water solubility.
|
-
- HY-N0420
-
|
Wormwood acid
|
Endogenous Metabolite
|
Neurological Disease
|
|
Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
- HY-126367
-
|
Acid Green 5
|
Fluorescent Dye
|
Others
|
|
Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains .
|
-
- HY-N0420R
-
|
Wormwood acid (Standard)
|
Reference Standards
Endogenous Metabolite
|
Neurological Disease
|
|
Succinic acid (Standard) is the analytical standard of Succinic acid. This product is intended for research and analytical applications. Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
- HY-D0256
-
|
Chlorazol Black E; Ferristatin II disodium; C.I. 30235
|
Biochemical Assay Reagents
|
Others
|
|
Direct Black 38 (Chlorazol Black E) is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
|
-
- HY-D0256A
-
|
Chlorazol Black E free acid; Ferristatin II; C.I. 30235 free acid
|
Biochemical Assay Reagents
|
Others
|
|
Direct Black 38 (Chlorazol Black E; Ferristatin II disodium) free acid is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 free acid is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 free acid can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
|
-
- HY-12695
-
|
5'-GTP trisodium salt
|
Endogenous Metabolite
DNA/RNA Synthesis
|
Others
|
|
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0075
-
|
|
Fluorescent Dyes/Probes
|
|
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .
|
-
- HY-D0217
-
|
Bromosulfophthalein disodium salt
|
Dyes
|
|
Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites .
|
-
- HY-15928
-
|
p-Nitrophenyl phosphate disodium
|
Chromogenic Substrates
|
|
4-Nitrophenyl phosphate (p-Nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.
|
-
- HY-D0994A
-
|
4-MUP disodium; MUP disodium
|
Chromogenic Substrates
|
|
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .
|
-
- HY-D1520
-
|
|
Fluorescent Dyes/Probes
|
|
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .
|
-
- HY-W879008
-
-
- HY-133424A
-
|
|
Fluorescent Dyes/Probes
|
|
Trisulfo-Cy3-acid disodium is a derivative of Cy3 (Cyanine3) dye. Trisulfo-Cy3-acid disodium contains three sulfonate ions and has improved water solubility.
|
-
- HY-D2238
-
-
- HY-W879370
-
-
- HY-D1676
-
|
|
Fluorescent Dyes/Probes
|
|
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
|
-
- HY-W879228
-
|
|
Fluorescent Dyes/Probes
|
|
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .
|
-
- HY-D1848
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-W151206
-
|
|
Dyes
|
|
Hydroxy naphthol blue disodium, an azo dye, is a metal indicator for calcium and a colorimetric reagent for alkaline earth metal ions ( λmax = 650 nm). In the pH range between 12 and 13, the solution of the indicator is reddish pink in the presence of calcium ion and to deep blue in the presence of disodium EDTA .
|
-
- HY-D1867
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-137896
-
|
|
Fluorescent Dyes/Probes
|
|
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium is a fluorescent dye. 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium can be used to demonstrate retrograde axonal transport to label secondary antibodies and as a fluorescent whole cell stain .
|
-
- HY-D0206
-
|
|
Dyes
|
|
Chromotropic acid disodium is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1851
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1160
-
|
Diiodofluorescein
|
Dyes
|
|
Diiodofluorescein disodium salt is a dye.
|
-
- HY-B0961
-
|
Mercury dibromofluorescein disodium salt; ZP1
|
Dyes
|
|
Merbromin is a mixed inhibitor of the 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2, with an IC50 of 2.7 μM. Merbromin effectively inhibits the replication of the Zika virus (ZIKV) and shows anti-ZIKV activity by inhibiting ZIKVpro. Merbromin can also be used as a topical disinfectant for cuts and scrapes, and it serves as a biological dye .
|
-
- HY-W748361
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3(Me)COOH sodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Trisulfo-Cy3-acid disodium contains sulfonate ions and has improved water solubility.
|
-
- HY-126367
-
|
Acid Green 5
|
Dyes
|
|
Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains .
|
-
- HY-D0256
-
|
Chlorazol Black E; Ferristatin II disodium; C.I. 30235
|
Dyes
|
|
Direct Black 38 (Chlorazol Black E) is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
|
-
- HY-D0256A
-
|
Chlorazol Black E free acid; Ferristatin II; C.I. 30235 free acid
|
Dyes
|
|
Direct Black 38 (Chlorazol Black E; Ferristatin II disodium) free acid is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 free acid is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 free acid can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W250127
-
|
Terephthalic acid disodium salt
|
Buffer Reagents
|
|
Disodium terephthalate (Terephthalic acid disodium salt) is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Disodium terephthalate can be used to build skin tumor models .
|
-
- HY-Y1324
-
|
disodium hydrogen phosphate dodecahydrate; disodium phosphate dodecahydrate
|
Buffer Reagents
|
|
Phosphoric acid disodium dodecahydrate is an inorganic compound and food additive. Phosphoric acid disodium dodecahydrate promotes gel formation, improves food texture and thermal properties of materials. Phosphoric acid disodium dodecahydrate induces glomerular calcification. Phosphoric acid disodium dodecahydrate can be used in kidney disease research .
|
-
- HY-W094516
-
|
Wormwood acid disodium hexahydrate
|
Biochemical Assay Reagents
|
|
Disodium succinate hexahydrate (Wormwood acid (disodium hexahydrate)) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-W250303A
-
|
Hydroxybutanedioic acid disodium hydrate; disodium DL-malate hydrate; E 296 disodium hydrate
|
Buffer Reagents
|
|
Malic acid disodium hydrate is an organic compound that is commonly used as a food additive, buffering agent, and nutritional supplement. It contains sodium and malic acid. Malic acid disodium hydrate has a variety of properties that make it suitable for these applications, including the ability to enhance food flavor, improve texture, and regulate acidity. In addition, due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance, Malic acid disodium hydrate can be used as a dietary supplement .
|
-
- HY-B0540
-
|
Sodium monofluorophosphate
|
Biochemical Assay Reagents
|
|
Disodium monofluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W105970
-
|
disodium pyrophosphate; Sodium acid pyrophosphate; SAPP
|
Biochemical Assay Reagents
|
|
Sodium pyrophosphate (Disodium pyrophosphate), a food additive, is an inorganic compound. Sodium pyrophosphate has potential hematotoxic and immunotoxic effects .
|
-
- HY-15908
-
|
disodium bicinchoninate
|
Biochemical Assay Reagents
|
|
BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 value of 28 µM, a Ki value of 43 µM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) .
|
-
- HY-Y0308E
-
|
disodium hydrogen phosphate, for cell culture
|
Buffer Reagents
|
|
Sodium phosphate dibasic (Disodium hydrogen phosphate), for cell culture is a buffer and chelating agent. Sodium phosphate dibasic is used to adjust the pH of liquids. Sodium phosphate dibasic can be used in cell culture .
|
-
- HY-W322022
-
|
|
Enzyme Substrates
|
|
Disodium Phenyl phosphate is a substrate for alkaline phosphatase .
|
-
- HY-Y0317E
-
|
disodium sulfate (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Sodium sulfate anhydrous (Disodium sulfate), can be widely used as a desiccant, pH regulator, etc. in biochemical experiments. It is a reference standard grade of the United States Pharmacopeia (USP), pharmaceutical primary standard.
|
-
- HY-W111522
-
|
di-Sodium hydrogen phosphite, 98%
|
Chelators
|
|
Sodium phosphite dibasic pentahydrate, 98% is a metal chelating agent used to remove copper ions from water supplies.
|
-
- HY-Y0308H
-
|
disodium hydrogen phosphate, for molecular biology
|
Buffer Reagents
|
|
Sodium phosphate dibasic, for molecular biology is an inorganic salt that can be used for life science related research .
|
-
- HY-Y0317H
-
|
disodium sulfate, for cell culture
|
Buffer Reagents
|
|
Sodium sulfate anhydrous, for cell culture is a drying agent in organic synthesis, which can be used for cell culture .
|
-
- HY-W094708C
-
|
disodium hydrogen phosphate dihydrate, for molecular biology
|
Buffer Reagents
|
|
Sodium phosphate dibasic dihydrate, for molecular biology is an inorganic salt compound. Sodium phosphate dibasic dihydrate, for molecular biology is commonly used in molecular biology experiments and can be used as a buffer, nutritional supplement, and detergent.
|
-
- HY-W094708D
-
|
disodium hydrogen phosphate dihydrate, meets analytical specification of Ph. Eur. BP
|
Buffer Reagents
|
|
Sodium phosphate dibasic dihydrate, meets analytical specification of Ph. Eur. BP is an inorganic salt that can be used for life science related research .
|
-
- HY-Y0317I
-
|
disodium sulfate, meets analytical specification of Ph. Eur. BP USP
|
Buffer Reagents
|
|
Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
|
-
- HY-Y0317IR
-
|
disodium sulfate, meets analytical specification of Ph. Eur. BP USP (Standard)
|
Buffer Reagents
|
|
Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP (Standard) is the analytical standard of Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP. This product is intended for research and analytical applications. Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
|
-
- HY-Y0308D
-
|
disodium hydrogen phosphate, meets analytical specification of Ph. Eur. BP USP FCC E339
|
Buffer Reagents
|
|
Sodium phosphate dibasic is commonly used as a food additive, buffer and laboratory reagent. Sodium phosphate dibasic has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions .
|
-
- HY-114294A
-
|
HMG-CoA disodium hydrate
|
Enzyme Substrates
|
|
DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor .
|
-
- HY-W010771
-
|
dCTP disodium; 2′-Deoxycytidine-5′-triphosphate disodium
|
Gene Sequencing and Synthesis
|
|
Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W011152
-
-
- HY-Y0682A
-
|
EDTA disodium dihydrate
|
Chelators
|
|
Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .
|
-
- HY-Y0682AR
-
|
EDTA disodium dihydrate (Standard)
|
Chelators
|
|
Ethylenediaminetetraacetic acid (disodium dihydrate) (Standard) is the analytical standard of Ethylenediaminetetraacetic acid (disodium dihydrate). This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research [4] .
|
-
- HY-W127530R
-
|
alpha-Tocopherol phosphate disodium (Standard); TocP disodium (Standard); Vitamin E phosphate disodium (Standard)
|
Biochemical Assay Reagents
|
|
α-Tocopherol phosphate (Standard) (alpha-Tocopherol phosphate (Standard)) disodium is the analytical standard of α-Tocopherol phosphate disodium (HY-W127530). This product is intended for research and analytical applications.
α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity .
|
-
- HY-W018746R
-
|
Ethylenediaminetetraacetic acid disodium (Standard)
|
Chelators
|
|
EDTA (disodium) (Standard) is the analytical standard of EDTA (disodium). This product is intended for research and analytical applications. EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
- HY-W127530
-
|
alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium
|
Biochemical Assay Reagents
|
|
α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity .
|
-
- HY-107921R
-
|
EDTA calcium disodium salt,98% (Standard); Adsorbonac,98% (Standard)
|
Chelators
|
|
EDTA Calcium disodium,98% (Standard) is the analytical standard of EDTA Calcium disodium,98%. This product is intended for research and analytical applications. EDTA Calcium disodium, 98% (EDTA calcium disodium salt, 98%; Adsorbonac, 98%) is a chelating agent for calcium and other metal ions, preventing them from participating in chemical reactions. It can effectively remove metal ions from solutions, preventing them from interfering with experimental processes.
|
-
- HY-W013098
-
|
5'-Dexoadenosine triphosphate disodium
|
Enzyme Substrates
|
|
2'-Deoxyadenosine 5'-triphosphate disodium (5'-Dexoadenosine triphosphate disodium) is a nucleotide with important biological activities and can serve as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. 2'-Deoxyadenosine 5'-triphosphate disodium plays a key role in DNA synthesis and reverse transcription. 2'-Deoxyadenosine 5'-triphosphate disodium is also widely used in in vitro reactions in molecular biology research.
|
-
- HY-136664A
-
|
|
Indicators
|
|
Neothorin (disodium) is a kind of biochemical reagent.
|
-
- HY-W392263
-
|
|
Carbohydrates
|
|
Glycerophosphate (disodium hydrate) is a biochemical assay reagent.
|
-
- HY-113238A
-
|
Sulfolithocholic acid disodium; LCAS disodium
|
Cell Assay Reagents
|
|
Lithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 41 and 42.4 (absence of Zn 2+) and 0.88 and 0.97 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Lithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Lithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-W018746
-
|
Ethylenediaminetetraacetic acid disodium
|
Chelators
|
|
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
|
-
- HY-W073082
-
|
Triglycollamic acid disodium salt
|
Biochemical Assay Reagents
|
|
Nitrilotriacetic acid disodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-D0199R
-
|
|
Biochemical Assay Reagents
|
|
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
|
-
- HY-D0199
-
|
|
Biochemical Assay Reagents
|
|
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
|
-
- HY-W749867
-
|
Calcium disodium EDTA dihydrate
|
Chelators
|
|
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .
|
-
- HY-W250119
-
|
EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
|
Surfactants
|
|
Calcium disodium edetate hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W011012R
-
|
|
Enzyme Substrates
|
|
Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
- HY-W011012
-
|
|
Enzyme Substrates
|
|
Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
- HY-W787630
-
-
- HY-W342120
-
|
|
Indicators
|
|
Phenolphthalein (disodium), 95% is a pH indicator.
|
-
- HY-W010854
-
|
dADP disodium
|
Gene Sequencing and Synthesis
|
|
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .
|
-
- HY-134433A
-
|
|
Carbohydrates
|
|
GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .
|
-
- HY-W040147
-
|
1,4-Piperazinediethanesulfonic acid disodium
|
Buffer Reagents
|
|
PIPES (1,4-Piperazinediethanesulfonic acid) disodium is an important component of PIPES buffer agent used in biochemistry .
|
-
- HY-W115799
-
|
Ethylenediaminetetraacetic acid disodium manganese
|
Chelators
|
|
Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-137255
-
|
3-Sulfotaurolithocholic acid disodium
|
Surfactants
|
|
Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 71.6 and 69.4 (absence of Zn 2+) and 9 and 9.6 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-W582564
-
|
Ethylenediaminetetraacetic acid copper disodium tetrahydrate
|
Chelators
|
|
Cu(Ⅱ)-EDTA disodium tetrahydrate, a typical contaminant in industrial wastewater, is an EDTA-complexed heavy metal. Cu(Ⅱ)-EDTA disodium tetrahydrate can be used in research on the recovery of heavy metal resources from mixed wastewater .
|
-
- HY-W115721
-
|
Sodium rhodizonate dibasic
|
Indicators
|
|
Rhodizonic acid disodium (Sodium rhodizonate dibasic) can be used as an indicator in the volumetric determination of barium and sulfates. Rhodizonic acid disodium is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-114364
-
|
|
Gene Sequencing and Synthesis
|
|
UDP-Galactose disodium is a natural agonist of the P2Y14 receptor with an EC50 of 0.67 μM for the hP2Y14 receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major .
|
-
- HY-116022A
-
|
p-Nitrophenyl phosphate disodium hexahydrate
|
Enzyme Substrates
|
|
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .
|
- HY-123065
-
|
|
Indicators
|
|
Chromotropic acid (disodium dihydrate) can be used for the detection of formaldehyde .
|
- HY-W110914A
-
|
|
Indicators
|
|
Xylenol orange,indicator (disodium) is a kind of biochemical reagent.
|
- HY-W713875
-
- HY-D0170
-
|
|
Indicators
|
|
Ferene disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W015883A
-
|
|
Biochemical Assay Reagents
|
|
Fumaric acid disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W127778
-
|
Pentacyanoamine ferrate ammonium disodium
|
Biochemical Assay Reagents
|
|
Ammonium disodium pentacyanoammineferrate(II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-D0855A
-
|
|
Buffer Reagents
|
|
ADA (disodium) is a buffer salt derived from ADA (adenosine deaminase) and is widely used in biochemical research, especially in the preparation of enzyme buffers.
|
- HY-107921
-
|
EDTA calcium disodium salt,98%; Adsorbonac,98%
|
Chelators
|
|
EDTA Calcium disodium, 98% (EDTA calcium disodium salt, 98%; Adsorbonac, 98%) is a chelating agent for calcium and other metal ions, preventing them from participating in chemical reactions. It can effectively remove metal ions from solutions, preventing them from interfering with experimental processes.
|
- HY-D0850
-
|
Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate
|
Chelators
|
|
Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications .
|
- HY-145934A
-
|
|
Gene Sequencing and Synthesis
|
|
UDP-GlcNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GlcNAc (HY-112174). UDP-GlcNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GlcNAc (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-157917
-
|
|
Chelators
|
|
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .
|
- HY-D0850R
-
|
Sodium tartrate dibasic dihydrate (Standard); Sodium tartrate dihydrate (Standard)
|
Chelators
|
|
Tartaric acid (disodium dihydrate) (Standard) is the analytical standard of Tartaric acid (disodium dihydrate). This product is intended for research and analytical applications. Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications [4].
|
- HY-W793605
-
|
|
Drug Delivery
|
|
(Rac)-Glycerol 1-phosphate (disodium hexahydrate) is a kind of biochemical reagent.
|
- HY-W134005
-
|
Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate
|
Chelators
|
|
Mg(Ⅱ)-EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (Km=0.9 μM). Mg(Ⅱ)-EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg 2+, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis .
|
- HY-W011061
-
- HY-W339545A
-
|
|
Cell Assay Reagents
|
|
α-Ketoglutaric acid disodium hydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium hydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties .
|
- HY-W127776
-
|
Ethylenediaminetetraacetic acid zinc disodium tetrahydrate
|
Chelators
|
|
Zn(Ⅱ)-EDTA (Ethylenediaminetetraacetic acid zinc) disodium tetrahydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-137942
-
|
α-Naphthyl phosphate disodium salt, 98%
|
Enzyme Substrates
|
|
1-Naphthyl phosphate disodium salt, 98% is a histochemical substrate for acidic and alkaline phosphatases, and can also be used as a substrate for measuring prostatic acid phosphatase.
|
- HY-W802699
-
|
|
Cell Assay Reagents
|
|
α-Ketoglutaric acid disodium dihydrate, an important dicarboxylic acid, is an intermediate in the tricarboxylic acid cycle (TCC) and amino acid metabolism. α-Ketoglutaric acid disodium dihydrate can be used as building block chemical for the chemical synthesis of heterocycles, dietary supplement, component of infusion solutions and wound healing compounds, or as main component of new elastomers with a wide range of interesting mechanical and chemical properties .
|
- HY-W145626
-
|
beta-D-Glucopyranose 1-phosphate disodium salt
|
Carbohydrates
|
|
β-D-Glucopyranose 1-Phosphate Disodium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W133934A
-
|
|
Chelators
|
|
EDTA magnesium disodium, 99% is a chelating agent with the ability to effectively bind metal ions (including calcium, magnesium, and iron) and remove them from solution.
|
- HY-131475A
-
|
|
Carbohydrates
|
|
Naphthol AS-BI phosphate (disodium hydrate) is used as a substrate for determining the activity of both alkaline and acidic phosphatases; it can also be used to measure the activity of individual cell acid phosphatase.
|
- HY-W010759
-
|
|
Gene Sequencing and Synthesis
|
|
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP .
|
- HY-W250156
-
|
|
Biochemical Assay Reagents
|
|
3-Acetylpyridine adenine dinucleotide (disodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W250303
-
|
Hydroxybutanedioic acid disodium salt; E 296 disodium salt
|
Biochemical Assay Reagents
|
|
Sodium DL-Malate is an organic compound commonly used as a food additive, buffer and nutritional supplement. It contains sodium and malic acid. Malic acid disodium salt has several properties suitable for these applications, including the ability to enhance food flavor, improve texture and regulate acidity. Additionally, it can be used as a dietary supplement due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance.
|
- HY-W127712
-
|
|
Enzyme Substrates
|
|
4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulphate (disodium) is a biochemical assay reagent.
|
- HY-114365
-
|
UDP-N-acetyl-D-galactosamine disodium
|
Gene Sequencing and Synthesis
|
|
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate of EpsC115. EpsC115 is an exopolymeric substances (EPS) N-terminal deletion mutant with the residue 1-115 deletion. UDP-GalNAc UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor .
|
- HY-W127790
-
|
|
Biochemical Assay Reagents
|
|
Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent for iron detection, with a wavelength of 535 nm for iron complex. It can be used for iron determination in aqueous solution systems without the need for extraction solvents. BPS can serve as a precursor to prepare Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) complex and ruthenium(II) tris(bathophenanthrolinedisulfonate), or participate in the catalytic oxidation of 2-hexanol by forming water-soluble complexes with palladium .
|
- HY-W854355
-
|
|
Carbohydrates
|
|
D-Mannose-6-phosphate (disodium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
- HY-W034953
-
|
|
Biochemical Assay Reagents
|
|
Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.
|
- HY-136830
-
|
Adenosine-5'-diphosphoglucose disodium
|
Carbohydrates
|
|
ADP-Glucose disodiumIs an immediate precursor for the biosynthesis of storage polysaccharides in plants, green algae and cyanobacteria, and structural polysaccharides in some bacteria, by the addition of glucose. It is used to produce amylose, amylopectin, starch and other polysaccharides by amylose synthase or starch synthase in plastids. ADPGUsually produced in plastids, although it can be biosynthesized in the cytoplasm of some grasses and imported into plastids by membrane-bound transporters .
|
- HY-W127640
-
|
|
Enzyme Substrates
|
|
Phosphocholine Chloride Sodium Salt is an organic compound containing phosphate, choline and chloride ions. It is commonly used to prepare cell membranes and liposomes for drug delivery systems. Phosphocholine Chloride Sodium Salt has various applications in the pharmaceutical industry, especially as a stabilizer and surfactant. In addition, it is used as an emulsifier and conditioning agent in the manufacture of cosmetic and personal care products.
|
- HY-W011271
-
|
1,4-Piperazinediethanesulfonic acid monosodium
|
Buffer Reagents
|
|
PIPES (1,4-Piperazinediethanesulfonic acid) monosodium is a pH buffer that can be mixed with another disodium salt form of PIPES. By changing the ratio and total amount of the PIPES monosodium and disodium buffers, the pH and ionic strength of the medium can be changed .
|
- HY-W776843
-
|
|
Carbohydrates
|
|
Glycochenodeoxycholic acid 3-sulfate (disodium) is a biochemical assay reagent.
|
- HY-W587911
-
|
|
Surfactants
|
|
N-β-D-Glucopyranosyloctanamide is a biochemical assay reagent.
|
- HY-157367
-
|
|
Microbial Culture
|
|
Bismuth Sulfite Agar Medium can be used for selective isolation and culture of Salmonella. Bismuth Sulfite Agar Medium ingredients include tryptone, peptone, beef powder, ferrous sulfate, bismuth sulfite, disodium hydrogen phosphate, glucose, brilliant green, agar .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-N0473A
-
-
- HY-105168
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-12590
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-D0887
-
-
-
- HY-F0001
-
-
-
- HY-F0001R
-
|
disodium NADH (Standard)
|
Structural Classification
Natural Products
Source classification
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
|
|
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .
|
-
-
- HY-B0345A
-
-
-
- HY-W015410
-
-
-
- HY-D0885B
-
-
-
- HY-100542
-
-
-
- HY-B0345AR
-
-
-
- HY-W015410R
-
|
|
Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
|
|
Disodium succinate (Standard) is the analytical standard of Disodium succinate. This product is intended for research and analytical applications. Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
-
- HY-100542R
-
-
-
- HY-N0666D
-
-
-
- HY-F0002A
-
-
-
- HY-100196A
-
-
-
- HY-16637D
-
-
-
- HY-W010970
-
-
-
- HY-17556A
-
-
-
- HY-B2176A
-
-
-
- HY-W010735R
-
-
-
- HY-N7097
-
-
-
- HY-B2176AR
-
|
|
Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Endogenous Metabolite
|
|
ATP (disodium trihydrate) (Standard) is the analytical standard of ATP (disodium trihydrate). This product is intended for research and analytical applications. ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
|
-
-
- HY-D0885D
-
-
-
- HY-12590
-
-
-
- HY-113149A
-
|
|
Structural Classification
Classification of Application Fields
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
Inflammation/Immunology
Disease Research Fields
|
Endogenous Metabolite
Reactive Oxygen Species (ROS)
|
|
Argininosuccinic acid disodium is an intermediate metabolite in the urea cycle, and its level is associated with argininosuccinic aciduria. Argininosuccinic acid disodium can induce oxidative stress, leading to lipid and protein oxidation, reduction of glutathione, and decrease in antioxidant enzyme activity. Argininosuccinic acid disodium can be converted into guanidinosuccinic acid, a nitric oxide mimic, under the action of nitric oxide-derived free radicals. Argininosuccinic acid disodium can be used in the research of metabolic diseases, renal failure, nervous system diseases, etc .
|
-
-
- HY-16502
-
-
-
- HY-D0885BR
-
|
|
Structural Classification
Source classification
Amino acids
Endogenous metabolite
|
Endogenous Metabolite
MAP3K
Akt
Mitochondrial Metabolism
ERK
Apoptosis
ROS Kinase
|
|
Phosphocreatine (disodium) (Standard) is the analytical standard of Phosphocreatine (disodium). This product is intended for research and analytical applications. Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. .
|
-
-
- HY-113038A
-
-
-
- HY-W008940R
-
-
-
- HY-N1443
-
-
-
- HY-W010735
-
-
-
- HY-110382
-
-
-
- HY-W013159
-
-
-
- HY-W013175R
-
-
-
- HY-D0199R
-
|
|
Structural Classification
Natural Products
Source classification
Endogenous metabolite
|
Endogenous Metabolite
|
|
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
|
-
-
- HY-N11287A
-
-
-
- HY-B1654AR
-
-
-
- HY-W779068
-
-
-
- HY-128738R
-
-
-
- HY-112169A
-
-
-
- HY-134433A
-
-
-
- HY-W015114R
-
-
-
- HY-113066A
-
|
GDP disodium salt
|
Structural Classification
Natural Products
Classification of Application Fields
Source classification
Endogenous metabolite
Inflammation/Immunology
Disease Research Fields
|
Endogenous Metabolite
Potassium Channel
|
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K + channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
|
-
-
- HY-N7032
-
|
UDP-D-Glucose disodium
|
Structural Classification
Natural Products
Source classification
Endogenous metabolite
|
Endogenous Metabolite
P2Y Receptor
|
|
Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.
|
-
-
- HY-113407A
-
-
-
- HY-F0002AR
-
|
|
Structural Classification
Microorganisms
other families
Animals
Ketones, Aldehydes, Acids
Source classification
Plants
|
Endogenous Metabolite
|
|
NADP (disodium salt) (Standard) is the analytical standard of NADP (disodium salt). This product is intended for research and analytical applications. NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
|
-
-
- HY-114364
-
-
-
- HY-W013175
-
-
-
- HY-N2021A
-
-
-
- HY-126304
-
-
-
- HY-W009371
-
-
-
- HY-W015883A
-
-
- HY-128738
-
-
- HY-W015114
-
-
- HY-17449
-
-
- HY-D0886
-
-
- HY-113066AR
-
|
|
Structural Classification
Natural Products
Source classification
Endogenous metabolite
|
Endogenous Metabolite
Potassium Channel
|
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
|
-
- HY-129963
-
-
- HY-112253A
-
-
- HY-W615108B
-
-
- HY-B1654A
-
-
- HY-W105272
-
-
- HY-113407CR
-
-
- HY-139793
-
-
- HY-128374
-
-
- HY-N7389B
-
-
- HY-128747
-
-
- HY-128747A
-
-
- HY-W011142
-
-
- HY-W010832
-
-
- HY-110385
-
-
- HY-D0885A
-
-
- HY-147063
-
-
- HY-147061
-
-
- HY-W009371C
-
-
- HY-114365
-
-
- HY-N8515C
-
-
- HY-W010737
-
-
- HY-N7389A
-
-
- HY-113044R
-
|
UDP-D-Glucose (Standard)
|
Structural Classification
Natural Products
Human Gut Microbiota Metabolites
Microorganisms
Source classification
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
P2Y Receptor
|
|
Uridine 5′-diphosphoglucose (Standard) (UDP-D-Glucose (Standard)) is the analytical standard of Uridine 5′-diphosphoglucose (HY-113044). This product is intended for research and analytical applications. Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.
|
-
- HY-113044
-
-
- HY-W008646R
-
-
- HY-108213AR
-
|
5'-IMP disodiumhydrate(1:2:X) (Standard); IMP disodiumhydrate(1:2:X) (Standard); Inosine 5'-(dihydrogen phosphate) disodiumhydrate(1:2:X) (Standard)
|
Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
|
|
Inosinic acid (disodium)(hydrate)(1:2:X) (Standard) is the analytical standard of Inosinic acid (disodium)(hydrate)(1:2:X). This product is intended for research and analytical applications. Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
|
-
- HY-100196AR
-
|
PQQ disodium salt (Standard); Methoxatin disodium salt (Standard)
|
Quinones
Structural Classification
Microorganisms
Source classification
Benzene Quinones
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
|
|
Triazophos (Standard) is the analytical standard of Triazophos. This product is intended for research and analytical applications. Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.
|
-
- HY-12326A
-
-
- HY-113038AR
-
|
2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard)
|
Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
|
Reference Standards
Histone Demethylase
Endogenous Metabolite
|
|
Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside . Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years .
|
-
- HY-108213A
-
-
- HY-N2021AR
-
-
- HY-107579R
-
|
AY 25712 (Standard)
|
Human Gut Microbiota Metabolites
Source classification
Endogenous metabolite
|
Reference Standards
GPR109A
|
|
(2S,5R,6R)-Ticarcillin (disodium) (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin (disodium). This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections.
|
-
- HY-N11102
-
-
- HY-147061R
-
-
- HY-W105272R
-
|
|
Structural Classification
Natural Products
Source classification
Endogenous metabolite
|
Reference Standards
Endogenous Metabolite
|
|
Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical applications. Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM . Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .
|
-
- HY-N2417
-
-
- HY-147063R
-
-
- HY-N0420
-
-
- HY-N0420R
-
-
- HY-12695
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W015410S
-
|
|
|
Disodium succinate- 13C2 is the 13C labeled Disodium succinate . Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism .
|
-
-
- HY-W654003
-
|
|
|
D-α-Hydroxyglutaric acid-d5 disodium (Disodium (R)-2-hydroxyglutarate-d5) is the deuterium labeled D-α-Hydroxyglutaric acid disodium (HY-100542). D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid disodium is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling .
|
-
-
- HY-B0302AS
-
|
|
|
Etidronic acid-d3 (disodium) is the deuterium labeled Etidronic acid disodium .
|
-
-
- HY-112174S
-
|
|
|
UDP-GlcNAc- 13C (disodium) is the 13C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O .
|
-
-
- HY-W015410S2
-
|
|
|
Disodium succinate-d4 is the deuterium labeled Disodium succinate . Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism .
|
-
-
- HY-136883S
-
|
|
|
Benzophenone-9-d6 (Disodium 3,3'-carbonylbis[4-hydroxy-6-methoxybenzenesulphonate]-d6) is deuterium labeled Benzophenone-9 .
|
-
-
- HY-10820AS
-
|
|
|
Pemetrexed-d5 disodium is the deuterium labeled Pemetrexed disodium. Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
|
-
-
- HY-A0294AS
-
|
|
|
Ertapenem-d4 (disodium) is deuterium labeled Ertapenem (disodium).
|
-
-
- HY-W769288
-
|
|
|
Pemetrexed disodium- 13C5 (LY231514 disodium- 13C5) is the 13C-labeled Pemetrexed disodium (HY-10820A). Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .
|
-
-
- HY-B0345AS
-
|
|
|
ATP- 18O4 (disodium salt) is the 18O labeled ATP disodium salt . ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .
|
-
-
- HY-W742557
-
|
|
|
Acetaminophen glutathione-d3 disodium is the deuterium labeled Acetaminophen glutathione disodium.
|
-
-
- HY-W766920
-
|
|
|
Olsalazine disodium- 13C12 is the 13C-labeled Olsalazine disodium (HY-B0174). Olsalazine Disodium is an anti-inflammatory compound that works in inflammatory bowel disease and ulcerative colitis.
|
-
-
- HY-113238AS
-
|
|
|
Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium .
|
-
-
- HY-Y0262BS
-
|
|
|
Oxalic Acid- 13C2 (disodium) is the 13C labeled Oxalic Acid disodium .
|
-
-
- HY-113038AS1
-
|
|
|
α-Hydroxyglutaric acid-d4 (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
|
-
-
- HY-W740049
-
|
|
|
N-Desmethyl rosuvastatin-d6 disodium salt is the deuterium labeled N-Desmethyl rosuvastatin disodium salt.
|
-
-
- HY-Z3203S
-
|
|
|
N-Desmethyl Rosuvastatin-d6 (disodium) is the deuterium labeled N-Desmethyl Rosuvastatin disodium .
|
-
-
- HY-131524S
-
|
|
|
Taurocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Taurocholic acid 3-sulfate disodium .
|
-
-
- HY-143840S
-
|
|
|
2-Hydroxy Atorvastatin-d5 (disodium) is the deuterium labeled 2-Hydroxy Atorvastatin disodium .
|
-
-
- HY-143645S
-
|
|
|
Glycochenodeoxycholic acid 3-sulfate-d5 (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium .
|
-
-
- HY-143017S
-
|
|
|
4-Hydroxy Atorvastatin-d5 (disodium) is the deuterium labeled 4-Hydroxy Atorvastatin disodium salt .
|
-
-
- HY-139614S
-
|
|
|
Cholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Cholic acid 3-sulfate disodium .
|
-
-
- HY-W700989
-
|
|
|
Methyl-D-erythritol phosphate-d3 disodium is the deuterium labeled Methyl-D-erythritol phosphate disodium.
|
-
-
- HY-W009162S
-
|
|
|
Cytidine 5′-monophosphate- 15N3 (disodium) is the 15N labeled Cytidine 5'-monophosphate disodium . Cytidine 5'-monophosphate (5'-Cytidylic acid) disodium is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate disodium consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .
|
-
-
- HY-150659S
-
|
|
|
Adenosine-5′-triphosphate-d14 (disodium) is the deuterium labeled Adenosine-5′-triphosphate disodium .
|
-
-
- HY-W011012S
-
|
|
|
Adenosine 5'-monophosphate- 13C (disodium) is a 13C-labeled Adenosine 5'-monophosphate (HY-W011012). Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
-
- HY-W011012S1
-
|
|
|
Adenosine 5'-monophosphate-d2 disodium is the deuterium labeled Adenosine 5'-monophosphate (HY-W011012). Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
|
-
-
- HY-152903S
-
|
|
|
Sulfuric-34S acid disodium is an active compound.
|
-
-
- HY-114364S
-
|
|
|
UDP-α-D-Galactose- 13C (disodium) is the 13C labeled UDP-α-D-Galactose disodium salt .
|
-
-
- HY-D0199S
-
|
|
|
Adenosine- 15N5 5′-diphosphate (disodium salt) is the 15N labeled Adenosine 5'-diphosphate disodium salt .
|
-
-
- HY-139610S
-
|
|
|
3-Sulfo-glycodeoxycholic acid-d4 (disodium) is the deuterium labeled 3-Sulfo-glycodeoxycholic acid disodium .
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-
- HY-W011012S2
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Adenosine-5'-monophosphate- 15N5 (disodium) is the deuterium labeled Adenosine 5'-monophosphate disodium salt .
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-
-
- HY-W015883AS
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Fumaric acid2,3- 13C2 (disodium) is the deuterium labeled Fumaric acid disodium .
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-
-
- HY-N7032S
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Uridine 5′-diphosphoglucose- 13C (UDP-D-Glucose- 13C) disodium is the 13C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032) . Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .
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-
-
- HY-B1657AS
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Fosphenytoin-d10 (disodium) is deuterium labeled Fosphenytoin (disodium). Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
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-
-
- HY-113407CS
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D-Fructose-6-phosphate disodium monohydrate- 13C6 is the 13C-labeled D-Fructose-6-phosphate disodium monohydrate (HY-113407C). D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
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-
-
- HY-113128S
-
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sn-Glycerol 3-phosphate- 13C3 disodium is the 13C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .
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-
-
- HY-W744986
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L-2-Hydroxyglutaric acid-d5 disodium ((2S)-2-Hydroxyglutaric acid-d5 disodium) is the deuterium labeled L-2-Hydroxyglutaric acid disodium (HY-W015114). L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively .
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-
-
- HY-W766913
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Moxifloxacin (N-Sulfate Disodium)- 13C,d3 is the deuterium labeled and 13C-labeled Moxifloxacin (N-Sulfate Disodium).
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-
-
- HY-144085S
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D-Fructose-6-phosphate- 13C6 disodium x.hydrate is a 13C-labeled D-Fructose-6-phosphate disodium x.hydrate .
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-
-
- HY-N7032S1
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Uridine 5′-diphosphoglucose- 13C6 (UDP-D-Glucose- 13C6) disodium is the 13C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032) . Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .
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-
- HY-W105272S
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2′-Deoxyadenosine 5′-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2′-Deoxyadenosine 5′-monophosphate disodium . 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
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-
- HY-141931S1
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Glycolithocholic acid 3-sulfate-d4 disodium is the deuterium labeled Glycolithocholic acid 3-sulfate (HY-113074) .
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-
-
- HY-W013175S2
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Uridine 5'-monophosphate- 13C9, 15N2 disodium is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt (HY-W013175). Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
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-
-
- HY-137255S
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Taurolithocholic Acid-3-Sulfate-d4 （disodium salt） is the deuterium labeled Taurolithocholic Acid-3-Sulfate .
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-
-
- HY-B0712S
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Ceftriaxone-d3 (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics .
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-
- HY-B1433S
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Perindoprilat-d3 disodium is deuterated labeled Perindoprilat (HY-B1433). Perindoprilat (S 9780) is an angiotensin-converting enzyme (ACE) inhibitor with the IC50 value ranging from 1.5 to 3.2 nM. Perindoprilat can be used in hypertension research .
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-
- HY-141719S
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N-Acetyl-S-(3-carboxy-2-propyl)-L-cysteine-d3 disodium is the deuterium labeled N-Acetyl-S-(3-carboxy-2-propyl)-L-cysteine disodium .
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-
-
- HY-124329AS
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BS3 Crosslinker-d4 (disodium) is the deuterium labeled BS3 Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
- HY-15027S3
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5-Aminosalicylic acid-d3 disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).
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- HY-141945S
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Taurochenodeoxycholic acid-3-o-glucuronide-d4 (disodium) is the deuterium labeled Taurochenodeoxycholic acid-3-o-glucuronide .
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-
- HY-128738S
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Thymidine-5'-monophosphate- 13C10, 15N2 (disodium) is the 13C and 15N labeled Thymidine-5'-monophosphate disodium salt . Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
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-
- HY-130547S
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BS2G Crosslinker-d4 (disodium) is the deuterium labeled BS2G Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
- HY-W768574
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Bisphenol A Bissulfate Disodium Salt- 13C12 is the 13C-labeled Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate (2:1) (HY-W587516).
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-
- HY-112537S1
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D-Glucose 6-Phosphate- 13C6 disodium xhydrate is the 13C labeled D-Glucose 6-phosphate (HY-112537) . D-Glucose 6-phosphate is a glucose sugar phosphorylated at the hydroxy group on carbon 6 .
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-
- HY-W779800
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D-α-Hydroxyglutaric acid- 13C5 disodium is the 13C-labeled D-α-Hydroxyglutaric acid (HY-113038). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-W013159S
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2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (dGMP- 13C10, 15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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- HY-125818S1
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Cytidine-5′-triphosphate-d14 disodium is the deuterium labeled Cytidine-5'-triphosphate . Cytidine 5′-triphosphate (Cytidine triphosphate;5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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- HY-A0181BS
-
1 Publications Verification
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Adenosine monophosphate- 13C10, 15N5 (AMP- 13C10, 15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
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- HY-W766835
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Bisphenol A bissulfate-d6 (disodium salt) (Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate-d6 (2:1)) is the deuterium labeled Sodium S,S′-[(1-methylethylidene)di-4,1-phenylene] disulfate (2:1) (HY-W587516).
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- HY-13570CS
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Betamethasone 21-phosphate-d5 is the deuterium labeled Betamethasone disodium phosphate. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids .
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- HY-W704805
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Sodium 2-hydroxypentanedioate-2,3,3-d3 is the deuterium labeled α-Hydroxyglutaric acid disodium (HY-113038A). α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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- HY-110382S
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13C20, 15N10-Cyclic di-GMP ( 13C20, 15N10-c-di-GMP) is 13C and 15N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .
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- HY-A0213AS
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Tiludronate-d5 (sodium)mis the deuterium labeled Tiludronate disodium. Tiludronate (Tiludronic Acid) disodium, an orally active bisphosphonate, can act an osteoregulator. Tiludronate is used for the research of the metabolic bone disorders. Tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase. Antiresorptive and anti-inflammatory properties .
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- HY-W013724S
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Inosine-5'-diphosphoric acid- 15N4 dilithium is 15N labeled Inosine-5'-diphosphoric acid (disodium) (HY-W013724).
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- HY-113038AS
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α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium . α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .
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| Cat. No. |
Product Name |
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Classification |
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- HY-145934A
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Azide
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UDP-GlcNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GlcNAc (HY-112174). UDP-GlcNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GlcNAc (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-145934
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UDP-N-azidoacetylgalactosamine disodium
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Azide
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UDP-GalNAz (UDP-N-azidoacetylgalactosamine) disodium is the analogue of UDP-GalNAc (HY-114365). UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W879008
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Azide
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DiSulfo-ICG-azide disodium is a fluorescent dye.
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- HY-W879370
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Alkynes
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Disulfo-ICG-alkyne disodium is a click chemistry reagent.
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- HY-W879228
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DBCO
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Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .
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- HY-134318B
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Azide
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8-Azido-ADP (disodium) is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP (disodium) causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP (disodium) inhibits the normal state 4 → 3 transitions of mitochondrial respiration induced by ADP . 8-Azido-ADP (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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| Cat. No. |
Product Name |
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Classification |
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- HY-Y1324
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disodium hydrogen phosphate dodecahydrate; disodium phosphate dodecahydrate
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pH Modifiers
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Phosphoric acid disodium dodecahydrate is an inorganic compound and food additive. Phosphoric acid disodium dodecahydrate promotes gel formation, improves food texture and thermal properties of materials. Phosphoric acid disodium dodecahydrate induces glomerular calcification. Phosphoric acid disodium dodecahydrate can be used in kidney disease research .
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-
- HY-Y0308
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Chelating Agents
pH Modifiers
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Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.
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- HY-F0002A
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disodium NADP
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Nucleotides and their Analogs
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NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
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- HY-W010771
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dCTP disodium; 2′-Deoxycytidine-5′-triphosphate disodium
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Nucleotides and their Analogs
C
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Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W010970
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5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt
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Nucleotides and their Analogs
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5'-Guanylic acid disodium salt is the disodium salt form of 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid disodium salt is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid disodium salt regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid disodium salt is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid disodium salt also causes neuronal cell death at high concentrations .
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-
- HY-W011152
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-
- HY-B2176A
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Adenosine-5'-triphosphate disodium trihydrate
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Nucleotides and their Analogs
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ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
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-
- HY-Y0682A
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EDTA disodium dihydrate
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Antioxidants
Chelating Agents
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Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .
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-
- HY-W013707
-
|
Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
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|
Nucleotides and their Analogs
C
|
|
Cytidine-5'-triphosphate disodium dihydrate (5'-CTP disodium dihydrate) is a molecule of high energy, and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation .
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-
- HY-W013098
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|
5'-Dexoadenosine triphosphate disodium
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|
Nucleotides and their Analogs
A
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|
2'-Deoxyadenosine 5'-triphosphate disodium (5'-Dexoadenosine triphosphate disodium) is a nucleotide with important biological activities and can serve as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. 2'-Deoxyadenosine 5'-triphosphate disodium plays a key role in DNA synthesis and reverse transcription. 2'-Deoxyadenosine 5'-triphosphate disodium is also widely used in in vitro reactions in molecular biology research.
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-
- HY-W013159
-
|
5′-dGMP disodium
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|
Nucleotides and their Analogs
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|
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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-
- HY-D0199
-
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Nucleotides and their Analogs
A
|
|
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
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-
- HY-W010854
-
|
dADP disodium
|
|
Nucleotides and their Analogs
A
|
|
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .
|
-
- HY-113066A
-
|
GDP disodium salt
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|
Nucleotides and their Analogs
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Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K + channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
|
-
- HY-113606
-
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|
|
Nucleotides and their Analogs
A
|
|
Adenosine 5'-phosphosulfate disodium is a metabolism intermediates of sulfur. Adenosine 5'-phosphosulfate disodium can used in study sulfotransferases and sulforeductases in various organisms .
|
-
- HY-W013100
-
|
Cytidine triphosphate disodium; 5'-CTP disodium
|
|
Nucleotides and their Analogs
C
|
|
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
|
-
- HY-160202
-
|
|
|
Phospholipids
|
|
18:1 Cardiolipin disodium is a virulence regulator with two phosphate groups and four acyl chains.18:1 Cardiolipin disodium can be used in the study of the regulation and mechanism of bacterial infection .
|
-
- HY-W013175
-
|
5'-Uridylic acid disodium salt
|
|
Nucleotides and their Analogs
|
|
Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea .
|
-
- HY-21586
-
|
m7GTP disodium
|
|
Nucleotides and their Analogs
G
|
|
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor .
|
-
- HY-128738
-
-
- HY-W008940
-
|
Cytidine diphosphate disodium
|
|
Nucleotides and their Analogs
C
|
|
Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .
|
-
- HY-D0850
-
|
Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate
|
|
Chelating Agents
|
|
Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications .
|
-
- HY-W105272
-
|
|
|
Nucleotides and their Analogs
|
|
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
|
-
- HY-W011061
-
-
- HY-137243
-
-
- HY-145934
-
|
UDP-N-azidoacetylgalactosamine disodium
|
|
Nucleotides and their Analogs
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UDP-GalNAz (UDP-N-azidoacetylgalactosamine) disodium is the analogue of UDP-GalNAc (HY-114365). UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W011142
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dUMP disodium
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Nucleotides and their Analogs
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2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
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- HY-W590551A
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- HY-W010759
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Nucleotides and their Analogs
I
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Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP .
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- HY-W010737
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5'-GTP disodium salt
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Nucleotides and their Analogs
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
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- HY-125818C
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Cytidine triphosphate disodium hydrate; 5'-CTP disodium hydrate
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Nucleotides and their Analogs
C
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Cytidine 5′-triphosphate is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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- HY-138227A
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3′-dADP disodium
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Nucleotides and their Analogs
A
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3′-Deoxyadenosine 5′-diphosphate (3′-dADP) disodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.
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- HY-N0420
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Wormwood acid
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Cosolvents
pH Modifiers
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Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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- HY-12695
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5'-GTP trisodium salt
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Nucleotides and their Analogs
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
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