Fostamatinib disodium hexahydrate (Standard)

Cat. No.: HY-13038BR Purity: ≥98%: Handling Instructions
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Fostamatinib (disodium hexahydrate) (Standard) is the analytical standard of Fostamatinib (disodium hexahydrate). This product is intended for research and analytical applications. Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

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Fostamatinib disodium hexahydrate (Standard) Chemical Structure

CAS No. : 914295-16-2

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Description	Fostamatinib (disodium hexahydrate) (Standard) is the analytical standard of Fostamatinib (disodium hexahydrate). This product is intended for research and analytical applications. Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
Molecular Weight	732.51
Formula	C₂₃H₃₆FN₆Na₂O₁₅P
CAS No.	914295-16-2
SMILES	COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O[Na])(O[Na])=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC.O.O.O.O.O.O
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Fostamatinib disodium hexahydrate (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fostamatinib disodium hexahydrate (Standard)914295-16-2SykFLT3Spleen tyrosine kinaseCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3Inhibitorinhibitorinhibit

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Fostamatinib disodium hexahydrate (Standard)

Product Information

Purity & Documentation

Customer Review

Fostamatinib disodium hexahydrate (Standard) Related Classifications

Molarity Calculator

Dilution Calculator