Search Result
Results for "
sulfated
" in MedChemExpress (MCE) Product Catalog:
108
Biochemical Assay Reagents
98
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W145658
-
|
Heparamine sodium salt
|
Biochemical Assay Reagents
|
Others
|
|
De-N-sulfated heparin (Heparin I-H) sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-W094475C
-
-
-
- HY-P2678
-
|
|
Cholecystokinin Receptor
|
Metabolic Disease
|
|
CCK (26-31) (non-sulfated) is the N-terminal fragment of CCK, a peptide hormone found in the gut and brain that stimulates digestion, regulates satiety, and is associated with anxiety. CCK (26-31) is also less active in non-sulfated than in sulfated form .
|
-
-
- HY-P4325
-
|
|
Thrombin
|
Others
|
|
Hirudin (55-65) (sulfated) is a fragment of Hirudin with anticoagulant effects. Hirudin is a thrombin inhibitor with blood anticoagulant property.
|
-
-
- HY-P2677
-
|
|
Cholecystokinin Receptor
|
Metabolic Disease
|
|
CCK (26-31) (sulfated) is the N-terminal fragment of CCK, a peptide hormone found in the gut and brain that stimulates digestion, regulates satiety, and is associated with anxiety .
|
-
-
- HY-P4795
-
|
|
Thrombin
|
Others
|
|
Acetyl-Hirudin (55-65) (sulfated) is a Acetyl-fragment of Hirudin. Hirudin is a thrombin inhibitor with blood anticoagulant property .
|
-
-
- HY-P2490
-
|
|
Thrombin
|
Metabolic Disease
|
|
Acetyl-Hirudin (54-65) (sulfated) is a acetyl-fragment of Hirudin which binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex .
|
-
-
- HY-129480
-
|
|
Drug Intermediate
|
Others
|
|
Vertilmicin sulfate combines with FMOC-Cl to form the Vertilmicin-FMOC-Cl adduct, and can be used for the determination of glucosamine sulfate in plasma .
|
-
-
- HY-P4721
-
|
|
Thrombin
|
Cardiovascular Disease
|
|
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an antithrombotic agent. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 μM .
|
-
-
- HY-W094477D
-
|
Epsom salts, for molecular biology
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
Magnesium sulfate heptahydrate, for molecular biology is a biochemical assay reagent and is suitable fo molecular biology.
|
-
-
- HY-P2165
-
-
-
- HY-E70171
-
|
EC:2.8.2.23; HS3ST1
|
Biochemical Assay Reagents
|
Endocrinology
|
|
Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure .
|
-
-
- HY-164090
-
-
-
- HY-P99694
-
|
JR-171
|
Transferrin Receptor
|
Neurological Disease
|
|
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I .
|
-
-
- HY-157424
-
|
PAPS tetralithium salt
|
Biochemical Assay Reagents
|
Others
|
|
3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt (PAPS tetralithium salt) is the cosubstrate and the source of sulfonic acid groups in sulfation reactions. 3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt is important for maintaining sulfation balance in living organisms .
|
-
-
- HY-172404
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Arylsulfatase is an enzyme catalyzing the hydrolysis of aryl sulfates. Arylsulfatase specifically cleaves sulfate ester bonds to release free phenols. Arylsulfatase is promising for research of tumor markers .
|
-
-
- HY-D0430
-
|
Tracid Brilliant Red B
|
Fluorescent Dye
|
Others
|
|
Acid Red 249 (Tracid Brilliant Red B) is a kind of weak acid dye containing sulfate ion .
|
-
-
- HY-W094475E
-
|
Epsom salts (Pharmaceutical primary standard, USP)
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
-
- HY-W115721
-
|
Sodium rhodizonate dibasic
|
Biochemical Assay Reagents
|
Others
|
|
Rhodizonic acid disodium (Sodium rhodizonate dibasic) can be used as an indicator in the volumetric determination of barium and sulfates. Rhodizonic acid disodium is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
-
- HY-W110904
-
|
|
Fluorescent Dye
|
Others
|
|
Methylthymol blue tetrasodium is a metallochromic indicator dye and can be used for determination of sulfate and calcium .
|
-
-
- HY-162297
-
|
|
Drug Metabolite
|
Others
|
|
4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids .
|
-
-
- HY-163388
-
|
|
Glycosidase
|
Others
|
|
CHI3L1-IN-2 (Compound 36) is a CHI3L1 (Chitinase-3-Like Protein 1) inhibitor. CHI3L1-IN-2 inhibits the? interaction between CHI3L1 and heparan sulfate (CHI3L1:HSIII), with an IC50 of 26 nM. CHI3L1, also known as YKL-40, is a glycoprotein associated with inflammation, fibrosis, and cancer .
|
-
-
- HY-N7699
-
|
|
Others
|
Infection
|
|
D-Dimannuronic acid is an alginate extract from brown algae which can be used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides .
|
-
-
- HY-N7699H
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
D-Dimannuronic acid is an alginate extract from brown algae which can be used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides .
|
-
-
- HY-P2803B
-
|
|
β-glucuronidase
|
Metabolic Disease
|
|
Beta-glucuronidase (helix pomatia) is a glycosyl hydrolase that hydrolyzes β-glucuronic acid and sulfate esters in urine and other biological fluids, and then releases β-glucuronate .
|
-
-
- HY-N9422
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Adenosine 3'-phosphate 5'-phosphosulfate triethylamine, is a universal sulfuryl donor for sulfation. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine (PAPS) is synthesized in the cytosol and subsequently translocated into the Golgi lumen via a PAPS transporter (PAPST) .
|
-
-
- HY-148225
-
|
|
Drug Metabolite
|
Cancer
|
|
Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer .
|
-
-
- HY-113238F
-
|
FITC-Sulfolithocholic acid
|
Fluorescent Dye
|
Others
|
|
FITC-Lithocholic acid 3-sulfate (FITC-Sulfolithocholic acid) is a FITC-labeled Lithocholic acid 3-sulfate, which is a sulfated biliary metabolite. Lithocholic acid 3-sulfate selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate can be used for the research of pathogenesis of cholestatic liver diseases .
|
-
-
- HY-Y0316S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Sodium-dodecyl sulfate-d25 is a deuterium labeled Sodium dodecyl sulfate. Sodium dodecyl sulfate is the most widely used of the anionic alkyl sulfate surfactants .
|
-
-
- HY-169231
-
|
|
Bcr-Abl
|
Cancer
|
|
BCR-ABL-IN-10 (compound B4) is a covalent and aryl vinyl sulfate (AVS)-containing BCR-ABL inhibitor with an IC50 of 43.1 nM for ABL kinase. BCR-ABL-IN-10 forms a covalent and stable adduct with ABL kinase, leading to sustained inhibition of endogenous BCR-ABL activities. BCR-ABL-IN-10 can be used for the study of chronic myeloid leukemia (CML) .
|
-
-
- HY-132641S
-
-
-
- HY-141931S
-
|
Glycolithocholate sulfate-d4 sodium; Sulfolithocholylglycine-d4 sodium; SLCG-d4 sodium
|
Isotope-Labeled Compounds
|
Others
|
|
Glycolithocholic acid 3-sulfate-d4 (sodium) is the deuterium labeled Glycolithocholic acid 3-sulfate .
|
-
-
- HY-141918S
-
-
-
- HY-113238S1
-
-
-
- HY-W743264
-
|
17β-Estradiol 3-sulfate-d6 sodium
|
Isotope-Labeled Compounds
GABA Receptor
|
Neurological Disease
|
|
17β-Estradiol sulfate-d3 sodium (17β-Estradiol 3-sulfate-d3 sodium) is the deuterium labeled 17β-Estradiol sulfate sodium (HY-141672). 17β-Estradiol sulfate sodium, also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
|
-
-
- HY-122009
-
|
Indoxyl-β-D-glucoside
|
P-glycoprotein
OAT
Fluorescent Dye
|
Others
|
|
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .
|
-
-
- HY-113360
-
-
-
- HY-131524S
-
-
-
- HY-143645S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Glycochenodeoxycholic acid 3-sulfate-d5 (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium .
|
-
-
- HY-144158S
-
-
-
- HY-139614S
-
-
-
- HY-141944S
-
-
-
- HY-113238AS
-
|
Sulfolithocholic acid-d4 disodium
|
Isotope-Labeled Compounds
|
Others
|
|
Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium .
|
-
-
- HY-W743434
-
-
-
- HY-154775S
-
-
-
- HY-113074
-
|
Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG
|
HIV
Endogenous Metabolite
|
Infection
Inflammation/Immunology
|
|
Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease .
|
-
-
- HY-141672S1
-
|
17β-Estradiol 3-sulfate-d4 sodium
|
GABA Receptor
|
Neurological Disease
|
|
17β-Estradiol sulfate-d4 (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
|
-
-
- HY-W746074S
-
-
-
- HY-142768S
-
-
-
- HY-W284558S
-
-
- HY-144152S
-
-
- HY-141931S1
-
-
- HY-W779068
-
-
- HY-141936S
-
-
- HY-141943S
-
-
- HY-141916S
-
-
- HY-137255S
-
-
- HY-141926S
-
-
- HY-141911S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Tauroursodeoxycholic Acid-3-Sulfate Sodium Salt-d4 is the deuterium labeled Tauroursodeoxycholic Acid-3-Sulfate Sodium Salt .
|
-
- HY-N2028A
-
|
Demethylwedelolactone 3-sulfate
|
Others
|
Cancer
|
|
Demethylwedelolactone Sulfate (Demethylwedelolactone 3-sulfate) is a coumestan isolated from Eclipta prostrata L. .
|
-
- HY-N8460A
-
|
Cortisol 21-sulfate sodium
|
Endogenous Metabolite
|
Endocrinology
|
|
Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin .
|
-
- HY-N8460
-
|
Cortisol 21-sulfate
|
Endogenous Metabolite
|
Endocrinology
|
|
Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin .
|
-
- HY-W654121
-
|
p-Tolyl sulfate-d4 potassium
|
Isotope-Labeled Compounds
Endogenous Metabolite
p38 MAPK
JNK
|
Inflammation/Immunology
|
|
p-Cresol sulfate-d4 (potassium) is deuterium labeled p-Cresyl sulfate (potassium). p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .
|
-
- HY-111660S
-
-
- HY-166257
-
-
- HY-66006S1
-
-
- HY-111431AS
-
|
p-Tolyl sulfate-d7 (potassium)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
p-Cresol sulfate-d7 (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].
|
-
- HY-W780275S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Alternariol-9-monomethylether sulfate-d3 (ammonium) is deuterium labeled Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt .
|
-
- HY-B1824R
-
|
HR-810 sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Cefpirome sulfate (Standard) is the analytical standard of Cefpirome sulfate. This product is intended for research and analytical applications. Cefpirome sulfate (HR-810 sulfate) is a fourth generation cephalosporin antibiotic.
|
-
- HY-116282P
-
|
|
Bacterial
|
Inflammation/Immunology
|
|
Dextran sulfate, high sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, high sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-116282J
-
|
|
Bacterial
|
Inflammation/Immunology
|
|
Dextran sulfate, low sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-116282M
-
|
|
Bacterial
|
Inflammation/Immunology
|
|
Dextran sulfate, low sulfate (MW 40000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 40000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-W009439
-
|
GlcN6P; D-Glucosamine-6-sulfate
|
Biochemical Assay Reagents
|
Others
|
|
Glucosamine 6-sulfate (GlcN6P) is an organic cofactor that splits phosphodiester bonds. Glucosamine 6-sulfate plays a variety of catalytic roles in glmS ribozymes .
|
-
- HY-66006S
-
-
- HY-143935S
-
-
- HY-132429S
-
-
- HY-66006AS
-
-
- HY-B1241R
-
|
DHSM sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Dihydrostreptomycin (sulfate) (Standard) is the analytical standard of Dihydrostreptomycin (sulfate) (HY-B1241). This product is intended for research and analytical applications. Dihydrostreptomycin sulfate (DHSM sulfate) is the sulfate salt form of Dihydrostreptomycin (HY-B1241A). Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin sulfate exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss .
|
-
- HY-129071R
-
|
|
Reference Standards
Microtubule/Tubulin
|
Cancer
|
|
Vindesine (sulfate) (Standard) is the analytical standard of Vindesine (sulfate). This product is intended for research and analytical applications. Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 μM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo .
|
-
- HY-111662
-
|
|
NOD-like Receptor (NLR)
|
Inflammation/Immunology
|
|
Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium (DSS; HY-116282C)-induced murine experimental colitis .
|
-
- HY-N0716BR
-
-
- HY-W654272
-
|
4-MU-α-idoa 2-sulfate sodium
|
Fluorescent Dye
|
Metabolic Disease
|
|
4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium is a fluorogenic substrate of iduronate-2-sulfatase (I2S). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be hydrolyzed by lysosomal enzyme α-l-iduronidase (IDUA) and release the fluorophore 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be used to detect Hurler syndrome .
|
-
- HY-143928S
-
-
- HY-142641S
-
-
- HY-B1241
-
|
DHSM sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Dihydrostreptomycin sulfate (DHSM sulfate) is the sulfate salt form of Dihydrostreptomycin (HY-B1241A). Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin sulfate exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss .
|
-
- HY-147323R
-
|
Ferulic acid 4-sulfate (Standard)
|
Reference Standards
Drug Metabolite
|
Cardiovascular Disease
|
|
Ferulic acid 4-O-sulfate (Standard) is the analytical standard of Ferulic acid 4-O-sulfate. This product is intended for research and analytical applications. Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice[1].
|
-
- HY-129040AR
-
|
MIBG sulfate (Standard)
|
Adrenergic Receptor
Reference Standards
|
Cancer
|
|
Iobenguane (sulfate) (Standard) is the analytical standard of Iobenguane (sulfate). This product is intended for research and analytical applications. Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .
|
-
- HY-147323
-
-
- HY-101406R
-
-
- HY-141672
-
|
17β-Estradiol 3-sulfate sodium
|
GABA Receptor
|
Neurological Disease
|
|
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
|
-
- HY-W740171
-
-
- HY-113293BS
-
|
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
Endogenous Metabolite
|
Cancer
|
|
Estrone sulfate-d5 (sodium) is the deuterium labeled Estrone sulfate sodium. Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer .
|
-
- HY-113293BS1
-
|
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Cancer
|
|
Estrone sulfate-d4 (sodium) is deuterium labeled Estrone sulfate (sodium). Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer .
|
-
- HY-146734S
-
-
- HY-126855S
-
|
7-Sulfocholic acid-d4
|
Isotope-Labeled Compounds
G protein-coupled Bile Acid Receptor 1
MHC
|
Metabolic Disease
|
|
Cholic acid 7-sulfate-d4 (7-Sulfocholic acid-d4) is the deuterium labeled Cholic acid 7-sulfate (HY-126855). Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation .
|
-
- HY-17423AR
-
|
Abacavir Hemisulfate (Standard); ABC sulfate (Standard)
|
Reference Standards
Reverse Transcriptase
HIV
Telomerase
Apoptosis
|
Infection
|
|
Abacavir (sulfate) (Standard) is the analytical standard of Abacavir (sulfate). This product is intended for research and analytical applications. Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity .
|
-
- HY-117179R
-
|
|
Reference Standards
Parasite
|
Infection
|
|
Endosulfan sulfate (Standard) is the analytical standard of Endosulfan sulfate. This product is intended for research and analytical applications. Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan .
|
-
- HY-111431AR
-
|
|
JNK
p38 MAPK
Reactive Oxygen Species (ROS)
|
Metabolic Disease
|
|
p-Cresyl sulfate (potassium) (Standard) is the analytical standard of p-Cresyl sulfate (potassium). This product is intended for research and analytical applications. p-Cresyl sulfate (p-Tolyl sulfate) potassium is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate potassium shows antiproliferation activity. p-Cresyl sulfate potassium increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate potassium induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways .
|
-
- HY-N0471AR
-
|
Daturine sulfate (Standard)
|
Reference Standards
mAChR
|
Neurological Disease
|
|
L-Hyoscyamine (sulfate) (Standard) is the analytical standard of L-Hyoscyamine (sulfate). This product is intended for research and analytical applications. L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate is a levo-isomer to Atropine (HY-B1205) .
|
-
- HY-W776843
-
-
- HY-146712S
-
-
- HY-B0472R
-
|
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
|
-
- HY-W129471R
-
|
Pentadecan-2-one (Standard)
|
Bacterial
Reference Standards
|
Others
|
|
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
|
-
- HY-146736S
-
-
- HY-B1370S
-
-
- HY-128442R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Phenyl sulfate (Standard) is the analytical standard of Phenyl sulfate. This product is intended for research and analytical applications. Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease .
|
-
- HY-137099A
-
|
|
Fluorescent Dye
|
Endocrinology
|
|
Genistein 7-sulfate sodium is a metabolite of genistein that can reduce the activity of estrogen agonists in MCF-7 cells. Genistein 7-sulfate sodium can promote the growth of MCF-7 cells at concentrations of 10 μM and above .
|
-
- HY-137099
-
|
|
Fluorescent Dye
|
Endocrinology
|
|
Genistein 7-sulfate is a metabolite of genistein that can reduce the activity of estrogen agonists in MCF-7 cells. Genistein 7-sulfate can promote the growth of MCF-7 cells at concentrations of 10 μM and above .
|
-
- HY-156836
-
|
Tyramine sulfate
|
Drug Metabolite
|
Neurological Disease
|
|
Tyramine O-sulfate (Tyramine sulfate) is a metabolite of Tyramine (HY-W007606) in urinary. Tyramine O-sulfate can be used as a marker for melancholia .
|
-
- HY-A0248R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Polymyxin B (Sulfate) (Standard) is the analytical standard of Polymyxin B (Sulfate). This product is intended for research and analytical applications. Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo .
|
-
- HY-111769
-
-
- HY-N0716B
-
-
- HY-13780R
-
|
Vincaleukoblastine sulfate salt (Standard)
|
Reference Standards
Microtubule/Tubulin
Autophagy
nAChR
|
Cancer
|
|
Vinblastine (sulfate) (Standard) is the analytical standard of Vinblastine (sulfate). This product is intended for research and analytical applications. Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
|
-
- HY-113416R
-
|
DHEA sulfate (Standard); Prasterone sulfate (Standard)
|
Reference Standards
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-12866AR
-
|
|
Trk Receptor
Apoptosis
|
Cancer
|
|
Larotrectinib sulfate (Standard) is the analytical standard of Larotrectinib sulfate. This product is intended for research and analytical applications. Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
|
-
- HY-B1445
-
|
|
Potassium Channel
|
Metabolic Disease
|
|
Minoxidil sulfate, a potent and ATP-sensitive K + channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo .
|
-
- HY-NP183
-
|
HSPG
|
Biochemical Assay Reagents
|
Others
|
|
Heparan sulfate proteoglycan (HSPG) is a glycoprotein composed of a core protein covalently bound to heparin sulfate chains. Heparan sulfate proteoglycan is an integral part of the basement membrane .
|
-
- HY-B1581AR
-
|
|
NO Synthase
|
Cancer
|
|
L-Canavanine (sulfate) (Standard) is the analytical standard of L-Canavanine (sulfate). This product is intended for research and analytical applications. L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.
|
-
- HY-N7065R
-
|
|
Drug Derivative
Reference Standards
|
Cardiovascular Disease
|
|
Dihydralazine sulfate (Standard) is the analytical standard of Dihydralazine sulfate (HY-N7065). This product is intended for research and analytical applications. Dihydralazine sulfate is a vasodilator and an antihypertensive agent.
|
-
- HY-B0800R
-
|
Guanethidine monosulfate (Standard)
|
Reference Standards
Adrenergic Receptor
|
Neurological Disease
|
|
Guanethidine (sulfate) (Standard) is the analytical standard of Guanethidine (sulfate). This product is intended for research and analytical applications. Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier .
|
-
- HY-B1222R
-
|
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [4].
|
-
- HY-17624AR
-
|
Neomycin B sulfate (Standard); Fradiomycin B sulfate (Standard)
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
|
Framycetin (sulfate) (Standard) is the analytical standard of Framycetin (sulfate). This product is intended for research and analytical applications. Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-B1018AS
-
-
- HY-143831S
-
-
- HY-B1134AS
-
-
- HY-15283AS
-
-
- HY-107867S
-
-
- HY-107867S3
-
-
- HY-150779S
-
-
- HY-B1824
-
-
- HY-W654100
-
-
- HY-129071
-
|
|
Microtubule/Tubulin
|
Cancer
|
|
Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 μM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo .
|
-
- HY-N3025
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and to prevent the condition in those at high risk .
|
-
- HY-W010973S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
5-Hydroxytryptamine-d4 creatinine sulfate monohydrate is the deuterium labeled 5-Hydroxytryptamine creatinine sulfate monohydrate. 5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.
|
-
- HY-113441S
-
|
MHPG sulfate-d3 potassium
|
Isotope-Labeled Compounds
|
Others
|
|
3-Methoxy-4-Hydroxyphenylglycol sulfate-d3 potassium is the deuterium labeled 3-Methoxy-4-Hydroxyphenylglycol sulfate potassium .
|
-
- HY-B1751B
-
-
- HY-W011910S
-
-
- HY-123742
-
|
|
P-glycoprotein
|
Metabolic Disease
|
|
Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17-(β -D-Glucuronide) transport with a Ki of 22 μM .
|
-
- HY-122389R
-
|
|
Herbicide
Reference Standards
|
Others
|
|
Difenzoquat methyl sulfate (Standard) is the analytical standard of Difenzoquat methyl sulfate. This product is intended for research and analytical applications. Difenzoquat methyl sulfate is a herbicide, which is used for post-emergence control of wild oats in cereal crops. Difenzoquat methyl sulfate is toxic to health and environment .
|
-
- HY-B1370R
-
|
HCQ sulfate (Standard)
|
Reference Standards
Parasite
Toll-like Receptor (TLR)
SARS-CoV
Autophagy
|
Infection
Cancer
|
|
Hydroxychloroquine (sulfate) (Standard) is the analytical standard of Hydroxychloroquine (sulfate). This product is intended for research and analytical applications. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .
|
-
- HY-D1633
-
|
|
Fluorescent Dye
|
Others
|
|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase .
|
-
- HY-129040A
-
|
MIBG sulfate
|
Adrenergic Receptor
|
Cancer
|
|
Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .
|
-
- HY-D1633A
-
|
|
Fluorescent Dye
|
Others
|
|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase .
|
-
- HY-141921S
-
|
DHEA sulfate sodium-d6; Prasterone sulfate sodium-d6
|
Isotope-Labeled Compounds
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Dehydroepiandrosterone sulfate sodium salt-d6 (DHEA sulfate sodium salt-d6; Prasterone sulfate sodium salt-d6) is the deuterium labeled Dehydroepiandrosterone sulfate sodium salt (HY-B0765). Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-B0765R
-
|
DHEA sulfate sodium (Standard); Prasterone sulfate sodium (Standard)
|
Reference Standards
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt (Standard) is the analytical standard of Dehydroepiandrosterone sulfate sodium salt (HY-B0765). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-111355
-
-
- HY-113415A
-
|
|
Endogenous Metabolite
Drug Metabolite
|
Endocrinology
|
|
Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone. Testosterone is the main male sex hormone which determination is useful for assessment of androgen status .
|
-
- HY-W019877
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Sodium sulfate decahydrate is a ubiquitous salt that reaches toxic concentrations due to mining and other industrial activities. Sodium sulfate can be used to enhance the conjugation of phenolic drugs with sulfate and to treat hypercalcemia .
|
-
- HY-E70186
-
|
EC:3.1.6.12; ARSB
|
Biochemical Assay Reagents
|
Others
|
|
Arylsulfatase B (EC:3.1.6.12, ARSB) removes a chemical group known as a sulfate from two GAGs called dermatan sulfate and chondroitin sulfate .
|
-
- HY-W587430
-
|
Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium
|
HIV
GPR39
|
Infection
Inflammation/Immunology
|
|
Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 47.9 and 66.8 μM (absence of Zn 2+) and 8 and 8.7 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .
|
-
- HY-111431
-
|
p-Tolyl sulfate
|
JNK
p38 MAPK
Reactive Oxygen Species (ROS)
|
Metabolic Disease
|
|
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate shows antiproliferation activity. p-Cresyl sulfate increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate activates the JNK and p38 MAPK signaling pathways .
|
-
- HY-113296S
-
-
- HY-176010
-
|
|
Drug Derivative
|
Others
|
|
Dehydroepiandrosterone sulfate 17-(O-carboxymethyl)oxime is a derivative of dehydroepiandrosterone sulfate .
|
-
- HY-111355S
-
-
- HY-166934S
-
-
- HY-B0186BR
-
|
FK-037 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Cefoselis (sulfate) (Standard) is the analytical standard of Cefoselis (sulfate). This product is intended for research and analytical applications. Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier[1][2][3].
|
-
- HY-B0441AR
-
|
Nebramycin Factor 6 sulfate (Standard); Deoxykanamycin B sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tobramycin (sulfate) (Standard) is the analytical standard of Tobramycin (sulfate). This product is intended for research and analytical applications. Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms[1].
|
-
- HY-157359
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
|
-
- HY-108826
-
|
Iduronate sulfate sulfatase
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Iduronate sulfatase (Iduronate sulfate sulfatase) is an exo-sulfatase that hydrolyzes the C2-sulfate ester bond from nonreducing terminal α-L-iduronic acid residues in HS .
|
-
- HY-B0802R
-
|
Terbutaline hemisulfate (Standard)
|
Reference Standards
Adrenergic Receptor
Antibiotic
|
Endocrinology
|
|
Terbutaline (sulfate) (Standard) is the analytical standard of Terbutaline (sulfate). This product is intended for research and analytical applications. Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol . Terbutaline sulfate can be used in asthma symptom research .
|
-
- HY-N0487R
-
|
|
Endogenous Metabolite
Reactive Oxygen Species (ROS)
HIF/HIF Prolyl-Hydroxylase
Autophagy
|
Inflammation/Immunology
Cancer
|
|
Glucosamine (sulfate) (Standard) is the analytical standard of Glucosamine (sulfate). This product is intended for research and analytical applications. Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
|
-
- HY-10119AR
-
|
SCH 530348 sulfate (Standard)
|
Reference Standards
Protease Activated Receptor (PAR)
|
Cardiovascular Disease
|
|
Vorapaxar (sulfate) (Standard) is the analytical standard of Vorapaxar (sulfate). This product is intended for research and analytical applications. Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
|
-
- HY-W017158R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
Vorapaxar (sulfate) (Standard) is the analytical standard of Vorapaxar (sulfate). This product is intended for research and analytical applications. Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
|
-
- HY-D1213
-
|
Dipotassium nitrocatechol sulfate
|
Biochemical Assay Reagents
|
Others
|
|
4-Nitrocatechol sulfate dipotassium salt (Dipotassium nitrocatechol sulfate) is a chromogenic substrate for sulphatase .
|
-
- HY-129899
-
-
- HY-W096997A
-
|
Sodium capryl sulfate, 95%
|
Biochemical Assay Reagents
|
Others
|
|
Sodium octyl sulfate (SOS), 95% (Sodium capryl sulfate, 95%) is an anionic detergent and ion-pairing agent.
|
-
- HY-B1304
-
|
(-)-Lupinidine sulfate pentahydrate
|
Sodium Channel
|
Cardiovascular Disease
|
|
(-)-Sparteine sulfate pentahydrate ((-)-Lupinidine sulfate pentahydrate) is a class 1a antiarrhythmic agent and a sodium channel blocker.
|
-
- HY-W115752
-
|
Diamine sulfate (99%)
|
Biochemical Assay Reagents
|
Others
|
|
Hydrazine sulfate (99%) (Diamine sulfate (99%)) is used as an insecticide, sterilant, and plant growth inhibitor in agriculture. Hydrazine sulfate (99%) is a biomaterial or organic compound that can be used in life science research .
|
-
- HY-113257
-
|
DA-4S; Dopamine 4-Sulfate
|
Drug Metabolite
|
Neurological Disease
|
|
Dopamine 4-sulfate (DA-4S) is an inactive metabolite of the catecholamine dopamine. It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3. Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate.
|
-
- HY-107813
-
|
BAY 41-6551 sulfate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .
|
-
- HY-17423A
-
|
Abacavir Hemisulfate; ABC sulfate
|
Reverse Transcriptase
HIV
Telomerase
Apoptosis
|
Infection
Cancer
|
|
Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity .
|
-
- HY-100589
-
|
Sch 21420 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance .
|
-
- HY-N10478A
-
|
|
Drug Derivative
|
Others
|
|
Sitosterol sulfate (trimethylamine) is an active compound. Sitosterol sulfate can be used in a variety of biological research .
|
-
- HY-135197
-
|
|
Drug Intermediate
|
Infection
|
|
L-Iduronic acid sodium salt is an important monosaccharide component of glycosaminoglycans (GAGs) such as Heparin, Heparan sulfate and Dermatan sulfate .
|
-
- HY-W769792
-
-
- HY-154768S
-
-
- HY-116282
-
|
DSS (MW 5000); DXS (MW 5000)
|
HIV
Complement System
Apoptosis
|
Infection
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
|
-
- HY-113293BR
-
|
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Cancer
|
|
Estrone sulfate (sodium) (Standard) is the analytical standard of Estrone sulfate (sodium). This product is intended for research and analytical applications. Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). Estrone sulfate can be used for the research of breast cancer .
|
-
- HY-W744217
-
|
7-HCS-d5(potassium)
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
7-Hydroxy coumarin sulfate-d5 potassium (7-HCS-d5 potassium) is the deuterium labeled 7-Hydroxy coumarin sulfate potassium (HY-129977). 7-Hydroxy coumarin sulfate (7-HCS) potassium is a metabolite of 7-Ethoxycoumarin (HY-133091) .
|
-
- HY-116282I
-
|
DSS (MW>500000); DXS (MW>500000)
|
Apoptosis
HIV
|
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (MW>500000) (DSS (MW>500000)) is a negatively charged sulfated polysaccharide. Dextran sulfate sodium salt has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate sodium salt can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-Y1267D
-
-
- HY-B1134A
-
|
Enilconazolel sulfate
|
Fungal
|
Infection
|
|
Imazalil (Enilconazole) sulfate is a fungicide. Imazalil sulfate has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil sulfate is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .
|
-
- HY-N6901
-
|
|
Epigenetic Reader Domain
|
Metabolic Disease
|
|
Luteolin 7-sulfate is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis .
|
-
- HY-122350
-
|
SF-2052 sulfate
|
Antibiotic
|
Infection
|
|
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .
|
-
- HY-A0248
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo .
|
-
- HY-131688R
-
|
|
PARP
Caspase
Reference Standards
|
Inflammation/Immunology
|
|
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .
|
-
- HY-Y1878
-
|
Cupric sulfate
|
Biochemical Assay Reagents
|
Others
|
|
Copper(Ⅱ) sulfate (Cupric sulfate) is an inorganic compound that is a source of copper ions. Copper(Ⅱ) sulfate forms coordination compounds through the coordination of copper ions with ligands. For example, it is used to synthesize anionic copper sulfate aggregates and chains for magnetic research. At the same time, Copper(Ⅱ) sulfate can be used as a copper supplement in animal nutrition to evaluate bioavailability, or participate in enzymatic reactions and material synthesis .
|
-
- HY-B0470R
-
|
|
Reference Standards
Bacterial
Antibiotic
Phospholipase
|
Infection
Cancer
|
|
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .
|
-
- HY-N0471A
-
|
Daturine sulfate
|
mAChR
|
Neurological Disease
|
|
L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate is a levo-isomer to Atropine (HY-B1205) .
|
-
- HY-Y1369C
-
|
Manganous sulfate monohydrate, for cell culture
|
Biochemical Assay Reagents
|
Others
|
|
Manganese sulfate monohydrate, for cell culture (Manganous sulfate monohydrate, for cell culture) can be used to prepare micronutrients. Manganese sulfate monohydrate, for cell culture is a biomaterial or organic compound that can be used as a life science research-related material .
|
-
- HY-148377
-
|
|
Drug Metabolite
|
Cancer
|
|
Abiraterone sulfate N-oxide is a carboxylic acid. Abiraterone sulfate N-oxide also is a major metabolite of Abiraterone (HY-70013). Abiraterone sulfate N-oxide can be used for the research of prostate cancer .
|
-
- HY-111431A
-
-
- HY-B1660
-
|
|
Adrenergic Receptor
|
Cardiovascular Disease
|
|
Guanadrel sulfate is an orally active, potent and postganglionic sympathetic inhibitor. Guanadrel sulfate lowers blood pressure by reducing systemic vascular resistance with little effect on cardiac output. Guanadrel sulfate is promising for research of hypertension .
|
-
- HY-17459R
-
|
(S)-(+)-Clopidogrel bisulfate (Standard); (S)-(+)-Clopidogrel hydrogen sulfate (Standard)
|
Reference Standards
Cytochrome P450
P2Y Receptor
|
Cardiovascular Disease
Cancer
|
|
Clopidogrel (hydrogen sulfate) (Standard) is the analytical standard of Clopidogrel (hydrogen sulfate). This product is intended for research and analytical applications. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation ．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
|
-
- HY-113238A
-
|
Sulfolithocholic acid disodium; LCAS disodium
|
GPR39
|
Others
Inflammation/Immunology
|
|
Lithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 41 and 42.4 (absence of Zn 2+) and 0.88 and 0.97 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Lithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Lithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-137255
-
|
3-Sulfotaurolithocholic acid disodium
|
GPR39
|
Inflammation/Immunology
|
|
Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 71.6 and 69.4 (absence of Zn 2+) and 9 and 9.6 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-17459S
-
|
(S)-(+)-Clopidogrel bisulfate-d3; (S)-(+)-Clopidogrel-d3 hydrogen sulfate
|
P2Y Receptor
Cytochrome P450
|
Cardiovascular Disease
|
|
Clopidogrel-d3 (hydrogen sulfate) is the deuterium labeled Clopidogrel hydrogen sulfate . Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
|
-
- HY-126855
-
|
7-Sulfocholic acid
|
G protein-coupled Bile Acid Receptor 1
MHC
|
Metabolic Disease
|
|
Cholic acid 7-sulfate (7-Sulfocholic acid) is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation .
|
-
- HY-17565
-
|
Bleomycin sulfate
|
DNA/RNA Synthesis
Antibiotic
|
Cancer
|
|
Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic .
|
-
- HY-W020772S
-
-
- HY-W020772S1
-
-
- HY-W714568
-
-
- HY-W654221
-
|
HCQ O-Sulfate sodium
|
Parasite
|
Infection
|
|
Hydroxychloroquine O-Sulfate (HCQ O-Sulfate) sodium is a derivative of the antimalarial agent Hydroxychloroquine (HY-W031727).
|
-
- HY-W654215
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Homovanillic acid sulfate (sodium) is a phenol that can be found in olive oil and a dopamine metabolite. Homovanillic acid sulfate (sodium) increases in response to acute renal injury in vivo. Homovanillic acid sulfate (sodium) can be used as a biomarker for early detection of kidney disease .
|
-
- HY-45609R
-
|
|
iGluR
Endogenous Metabolite
|
Neurological Disease
|
|
L-Cysteine S-sulfate (sodium hydrate) (Standard) is the analytical standard of L-Cysteine S-sulfate (sodium hydrate). This product is intended for research and analytical applications. L-Cysteine S-sulfate sodium hydrate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist. L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry operations .
|
-
- HY-B1751D
-
-
- HY-10962R
-
|
|
JAK
Autophagy
Apoptosis
|
Cancer
|
|
Momelotinib (sulfate) (Standard) is the analytical standard of Momelotinib (sulfate). This product is intended for research and analytical applications. Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).
|
-
- HY-Y1103
-
|
Ferrous sulfate heptahydrate, 99%
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
|
Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .
|
-
- HY-N0677AR
-
|
Potassium dehydroandrographolide succinate (Standard)
|
Antibiotic
Reference Standards
|
Infection
Inflammation/Immunology
Cancer
|
|
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .
|
-
- HY-17624A
-
|
Neomycin B sulfate; Fradiomycin B sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .
|
-
- HY-N0113A
-
|
Ordenina sulfate; Peyocactine sulfate
|
Antibiotic
|
Others
|
|
Hordenine sulfate (Ordenina sulfate) is an active compound extracted from malted barley that has melanin-inhibiting activity. Hordenine sulfate significantly reduced melanin content and reduced intracellular cAMP levels. Hordenine sulfate inhibits the expression of proteins related to melanogenesis, including microblind transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2. Therefore, Hordenine sulfate can be used as an active ingredient to inhibit pigmentation .
|
-
- HY-B0394R
-
|
Tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)
|
Reference Standards
mAChR
|
Cardiovascular Disease
Neurological Disease
|
|
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
|
-
- HY-17367AR
-
|
BMS-232632 sulfate (Standard)
|
Reference Standards
HIV
HIV Protease
SARS-CoV
Cytochrome P450
P-glycoprotein
Endogenous Metabolite
|
Infection
Cancer
|
|
Atazanavir (sulfate) (Standard) is the analytical standard of Atazanavir (sulfate). This product is intended for research and analytical applications. Atazanavir (BMS-232632) sulfate, a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration . Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp) . Atazanavir sulfate is also a SARS-CoV 3CLpro inhibitor with an IC50 of
3.49 μM .
|
-
- HY-B1205AR
-
|
Tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)
|
Reference Standards
mAChR
|
Cardiovascular Disease
Neurological Disease
|
|
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
|
-
- HY-B0956R
-
|
Aminosidine sulfate (Standard)
|
Reference Standards
Antibiotic
Parasite
Bacterial
|
Infection
|
|
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .
|
-
- HY-116282A
-
|
DSS (MW 4500-5500); DXS (MW 4500-5500)
|
HIV
Apoptosis
Complement System
|
Infection
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (DSS) (MW 4500-5500) is a polymer of dehydrated glucose with a molecular weight of approximately 4500-5500. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 4500-5500) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 4500-5500) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (MW 4500-5500) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 4500-5500) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
|
-
- HY-113416AS
-
|
DHEA sulfate-d6 sodium dihydrate; Prasterone sulfate-d6 sodium dihydrate
|
Isotope-Labeled Compounds
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Dehydroepiandrosterone sulfate sodium dihydrate-d6 sodium dihydrate is the deuterium labeled Dehydroepiandrosterone sulfate sodium dihydrate. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium dihydrate is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium dihydrate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium dihydrate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium dihydrate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium dihydrate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-N0488S2
-
|
Leurocristine-d6 sulfate; NSC-67574-d6 sulfate; 22-Oxovincaleukoblastine-d6 sulfate
|
Isotope-Labeled Compounds
Microtubule/Tubulin
Apoptosis
|
Cancer
|
|
Vincristine-d6 (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
|
-
- HY-172163
-
-
- HY-172163C
-
-
- HY-172163A
-
-
- HY-B1206R
-
-
- HY-172163B
-
-
- HY-A0276R
-
|
|
Reference Standards
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Gentamicin (sulfate) (Standard) is the analytical standard of Gentamicin (sulfate). This product is intended for research and analytical applications. Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM .
|
-
- HY-W145483
-
|
N-Acetyl-de-O-sulfated heparin (Heparin IV-A) (sodium)
|
Biochemical Assay Reagents
|
Others
|
|
Heparin IV-A sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-A0089R
-
|
Polymyxin E sulfate (Standard)
|
Reference Standards
Bacterial
Autophagy
Antibiotic
|
Infection
|
|
Colistin (sulfate) (Standard) is the analytical standard of Colistin (sulfate). This product is intended for research and analytical applications. Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
|
-
- HY-128442
-
|
Phenyl hydrogen sulfate
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease .
|
-
- HY-116282D
-
|
DSS (MW 450000-550000); DXS (MW 450000-550000)
|
HIV
Influenza Virus
|
Others
|
|
Dextran sulfate sodium salt (DSS) (MW 450000-550000) is a polymer of dehydrated glucose with a molecular weight of approximately 450000-550000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 450000-550000) inhibits replication of HIV-1 and influenza A virus. Dextran sulfate sodium salt (MW 450000-550000) can be formulated as nanoparticles and shows antibacterial activity. Dextran sulfate sodium salt (MW 450000-550000) can be used for functional material preparation .
|
-
- HY-Y0316BR
-
|
Sodium lauryl sulfate for electrophoresis (Standard); Laurylsulfuric acid sodium salt for electrophoresis (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
Sodium dodecyl sulfate for electrophoresis (Standard) is the analytical standard of Sodium dodecyl sulfate for electrophoresis. This product is intended for research and analytical applications. Sodium dodecyl sulfate for electrophoresis is a high purity sodium dodecyl sulfate (SDS) with a minimum purity of 98.5%. It is an anionic detergent commonly used in electrophoretic procedures to denature and impart a negative charge to proteins, allowing separation based on size and charge. Sodium dodecyl sulfate for electrophoresis has unique chemical properties that make it an effective ingredient in many laboratory applications, helping to improve the resolution and sensitivity of protein analysis.
|
-
- HY-150526
-
|
|
Endogenous Metabolite
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
|
-
- HY-101048
-
|
|
Bacterial
|
Infection
Metabolic Disease
|
|
Synthalin A sulfate is a biguanylated diamine with antibacterial and hypoglycemic properties. Synthalin A sulfate against S. aureus with a MIC of 64 μg/mL .
|
-
- HY-W751109
-
-
- HY-P3025
-
-
- HY-154744S
-
-
- HY-111660S1
-
-
- HY-127128
-
|
ACC-9089 sulfate
|
Adrenergic Receptor
|
Neurological Disease
|
|
Flestolol (ACC-9089) sulfate is a competitive, ultra-short-acting beta-adrenergic blocking agent. Flestolol sulfate shows a half-life of approximately 6.5 minutes. Flestolol sulfate has the potential for the research of chest pain .
|
-
- HY-N0488S
-
|
Leurocristine-d3 sulfate; NSC-67574-d3 sulfate; 22-Oxovincaleukoblastine-d3 sulfate
|
Isotope-Labeled Compounds
Microtubule/Tubulin
Apoptosis
|
Cancer
|
|
Vincristine-d3 (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM .
|
-
- HY-W051140
-
|
Disilver sulfate, 99%
|
Biochemical Assay Reagents
|
Others
|
|
Silver sulfate, 99% (Disilver sulfate, 99%) can be used for colorimetric determination of nitrates, phosphates, and fluoride, or for the determination of chromium and cobalt in water. Silver sulfate, 99% is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-N0488S1
-
|
Leurocristine-d3-ester sulfate; NSC-67574-d3-ester sulfate; 22-Oxovincaleukoblastine-d3-ester sulfate
|
Microtubule/Tubulin
Apoptosis
|
Cancer
|
|
Vincristine-d3-ester (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM .
|
-
- HY-101422A
-
|
|
Potassium Channel
|
Inflammation/Immunology
|
|
GAL-021 sulfate is a potent BKCa-channel blocker. GAL-021 sulfate inhibits KCa1.1 in GH3 cells. GAL-021 sulfate is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 sulfate increases minute ventilation in rats and non-human primates .
|
-
- HY-B0510A
-
|
|
Antifolate
Bacterial
Antibiotic
Influenza Virus
|
Infection
Cancer
|
|
Trimethoprim sulfate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim sulfate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim sulfate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim sulfate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
- HY-Y1878C
-
|
Cupric sulfate anhydrous, 99%
|
Bacterial
|
Infection
Metabolic Disease
|
|
Anhydrous copper sulfate, 99% (Cupric sulfate anhydrous, 99%) is an orally administerable disinfectant. Anhydrous copper sulfate, 99% can be used as a biomaterial or organic compound related to life sciences research, and it can increase the Cu content in rat organs .
|
-
- HY-N0488R
-
|
Leurocristine sulfate (Standard); NSC-67574 sulfate (Standard); 22-Oxovincaleukoblastine sulfate (Standard)
|
Reference Standards
Microtubule/Tubulin
Apoptosis
|
Cancer
|
|
Vincristine (sulfate) (Standard) is the analytical standard of Vincristine (sulfate). This product is intended for research and analytical applications. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
|
-
- HY-128420
-
|
α-Lobeline sulfate; L-Lobeline sulfate
|
nAChR
Dopamine Transporter
|
Neurological Disease
|
|
Lobeline (α-Lobeline) sulfate is a brain-penetrant nicotinic receptor agonist. Lobeline sulfate increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage. Lobeline sulfate is effective in smoking cessation .
|
-
- HY-W276164
-
|
Sodium stearyl sulfate
|
Biochemical Assay Reagents
|
Others
|
|
Sodium octadecyl sulfate (Sodium stearyl sulfate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-B1222
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria.
|
-
- HY-117179
-
|
|
Parasite
|
Infection
|
|
Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan .
|
-
- HY-160992
-
-
- HY-N0491
-
|
(-)-Lupinidine sulfate
|
nAChR
|
Neurological Disease
|
|
(-)-Sparteine (sulfate) is a quinolizidine alkaloid that can be extracted from Lupinus. (-)-Sparteine (sulfate) inhibits the release of acetylcholine and has anticonvulsant effects .
|
-
- HY-14928A
-
-
- HY-Y1103A
-
|
Ferrous sulfate heptahydrate, for cell culture, 99%
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
|
Iron(II) sulfate heptahydrate, for cell culture, 99% (Ferrous sulfate heptahydrate, for cell culture, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, for cell culture, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, for cell culture, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, for cell culture, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .
|
-
- HY-101238R
-
-
- HY-104026CS
-
-
- HY-12866A
-
|
LOXO-101 sulfate; ARRY-470 sulfate
|
Trk Receptor
Apoptosis
|
Cancer
|
|
Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
|
-
- HY-Y1881A
-
|
|
Biochemical Assay Reagents
Reactive Oxygen Species (ROS)
MyD88
SOD
Caspase
|
Neurological Disease
Metabolic Disease
Cancer
|
|
Copper sulfate pentahydrate, 99% is a biochemical reagent. Copper sulfate pentahydrate, 99% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, 99% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, 99% is cytotoxic to various cells. Copper sulfate pentahydrate, 99% has antioxidant activity. Copper sulfate pentahydrate, 99% can be used in the research of diabetes, Parkinson's disease and DMBA (HY-W011845)-induced tumors .
|
-
- HY-B0765
-
|
DHEA sulfate sodium; Prasterone sulfate sodium
|
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-113416
-
|
DHEA sulfate; Prasterone sulfate
|
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-W020772AS1
-
-
- HY-W020772AS
-
-
- HY-W019950
-
|
Chromic potassium sulfate (98%); Chrome alum (98%)
|
Biochemical Assay Reagents
|
Others
|
|
Chromium(Ⅲ) potassium sulfate dodecahydrate (98%) (Chromic potassium sulfate (98%); Chrome alum (98%)), can be used as a fixative for microscopic analysis. Chromium(Ⅲ) potassium sulfate dodecahydrate (98%) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-B1370
-
-
- HY-137432D
-
|
BEY1107 sulfate
|
CDK
Apoptosis
|
Cancer
|
|
Avotaciclib (BEY1107) sulfate is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib sulfate can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib sulfate can be used in the research of cancer such as pancreatic cancer and lung cancer .
|
-
- HY-B0186B
-
|
FK-037
|
Bacterial
Antibiotic
|
Infection
|
|
Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier .
|
-
- HY-116282B
-
|
DSS (MW 16000-24000); DXS (MW 16000-24000)
|
Biochemical Assay Reagents
STING
|
Others
|
|
Dextran sulfate sodium salt (DSS) (MW 16000-24000) is a polymer of dehydrated glucose with a molecular weight of approximately 16000-24000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 16000-24000) induces STING polymerization and TBK1 activation .
|
-
- HY-N6665R
-
|
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
|
Cefquinome (sulfate) (Standard) is the analytical standard of Cefquinome (sulfate). This product is intended for research and analytical applications. Cefquinome sulfate is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae .
|
-
- HY-Y1267
-
-
- HY-116282W
-
|
DSS (MW 6500-10000); DXS (MW 6500-10000)
|
HIV
|
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .
|
-
- HY-E70172
-
|
EC:2.8.2.23; HS3ST4; 3-OST-4
|
Notch
|
Neurological Disease
|
|
Heparan Sulfate 3-O-Sulfotransferase 4 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase 4 regulates Notch signaling .
|
-
- HY-167815
-
|
|
Biochemical Assay Reagents
|
|
|
Myo-Inositol hexasulfate hexapotassium is a sulfated derivative of inositol that has the activity of mimicking highly sulfated polysaccharides such as heparin, affecting many cell signaling pathways.
|
-
- HY-W134301
-
|
Potassium alum
|
Biochemical Assay Reagents
|
Others
|
|
Aluminum potassium sulfate (Potassium alum) is a biochemical agent that has water purification and antibacterial activity. Aluminum potassium sulfate can be used in the research of microbiology and environmental science .
|
-
- HY-101916
-
-
- HY-138697A
-
|
VOB560 sulfate
|
Bcl-2 Family
Apoptosis
|
Cancer
|
|
S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, is a proagent of S55746. S65487 sulfate is also active on BCL-2 mutations, such as G101V and D103Y. S65487 sulfate has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 sulfate induces apoptosis and has anticaner activities .
|
-
- HY-101238S
-
-
- HY-100373
-
|
BAL8557-002
|
Fungal
|
Infection
|
|
Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis .
|
-
- HY-109051C
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Arfolitixorin sulfate is a potent 5-Fluorouracil (5-FU) moderator. Arfolitixorin sulfate is an immediately active form of Folate, [6R]-5,10-methylenetetrahydrofolate ([6R]-MTHF). Arfolitixorin sulfate is potent for the research of metastatic colorectal cancer .
|
-
- HY-104026BS
-
-
- HY-W928617
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
|
-
- HY-B0560B
-
|
Baryta white
|
Biochemical Assay Reagents
|
Others
|
|
Barium sulfate (Baryta white) can be used as an opacifier. Barium sulfate is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-W766913
-
-
- HY-122389
-
|
|
Herbicide
|
Others
|
|
Difenzoquat methyl sulfate is a herbicide, which is used for post-emergence control of wild oats in cereal crops. Difenzoquat methyl sulfate is toxic to health and environment .
|
-
- HY-13780
-
|
Vincaleukoblastine sulfate salt
|
Microtubule/Tubulin
nAChR
Autophagy
|
Cancer
|
|
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
|
-
- HY-A0086R
-
|
SCH-20569 sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Netilmicin sulfate (Standard) is the analytical standard of Netilmicin sulfate (HY-A0086). This product is intended for research and analytical applications. Netilmicin (Sch 20569) sulfate is a broad-spectrum semisynthetic aminoglycoside antibiotic. Netilmicin sulfate exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL .
|
-
- HY-N0252B
-
|
(+)-3,4-Didehydrocoronaridine Sulfate
|
Calcium Channel
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Catharanthine ((+)-3,4-Didehydrocoronaridine) Sulfate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca 2+ channel (VOCC). Catharanthine Sulfate has IC50s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Sulfate lowers blood pressure (BP), heart rate (HR). Catharanthine Sulfate has anti-cancer activity .
|
-
- HY-N0487
-
-
- HY-156199
-
|
|
Others
|
Inflammation/Immunology
Cancer
|
|
o-Cresol sulfate is a biomarker related to CAR T cell-independent and dependent metabolic and inflammatory. o-Cresol sulfate can be used to predict patient response .
|
-
- HY-B0800
-
-
- HY-W009454
-
|
4-Nitopheyl Sulfate potassium
|
Fluorescent Dye
|
Others
|
|
p-Nitrophenyl Sulfate Potassium is a chromogenic substrate for arylsulfatase. p-Nitrophenyl Sulfate Potassium is released by arylsulfonase cleavage, and the activity of arylsulfonase can be quantitatively determined by colorimetric detection at 400 nm .
|
-
- HY-172443
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Keratin sulfate is a heparin-related proteoglycan that interacts with the receptor or alters its stability and function. Keratin sulfate does not enhance the mitogenic effect of FGF-2 .
|
-
- HY-153745A
-
|
|
Trk Receptor
|
Cancer
|
|
Protein kinase inhibitor 5 sulfate hydrate is a potent TRK-A inhibitor with an IC50 value of 1.8 nM. Protein kinase inhibitor 5 sulfate hydrate inhibits cell viability .
|
-
- HY-100799
-
|
|
GABA Receptor
|
Neurological Disease
|
|
ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM .
|
-
- HY-100652A
-
|
|
Factor Xa
|
Cardiovascular Disease
|
|
O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM .
|
-
- HY-W040128
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Kanamycins sulfate is a broad-spectrum antibiotic, can be used in certain severe staphylococcal or Gram-negative bacillary infections. Kanamycin sulfate has certain ototoxicity .
|
-
- HY-117651R
-
|
|
Reference Standards
Acyltransferase
|
Cancer
|
|
Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .
|
-
- HY-P0263R
-
|
|
Reference Standards
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
|
-
- HY-17459
-
|
(S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate
|
Cytochrome P450
P2Y Receptor
|
Cardiovascular Disease
Cancer
|
|
Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation ．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
|
-
- HY-W010668R
-
|
|
Flavivirus
Dengue Virus
Reference Standards
Parasite
Potassium Channel
|
Others
|
|
Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .
|
-
- HY-16566AR
-
|
Kanamycin A sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
|
-
- HY-137855
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.
|
-
- HY-17367A
-
-
- HY-B0402B
-
|
1-Adamantanamine sulfate; 1-Aminoadamantane sulfate
|
Influenza Virus
Orthopoxvirus
SARS-CoV
Apoptosis
CDK
Bcl-2 Family
|
Infection
Neurological Disease
Cancer
|
|
Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
|
-
- HY-116282H
-
|
DSS (MW 9000-20000); DXS (MW 9000-20000)
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (DSS) (MW 9000-20000) is a polymer of dehydrated glucose with a molecular weight of approximately 9000-20000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 9000-20000) is a biocompatible and biodegradable biochemical reagent and can be used for pharmaceutical and biomedical applications .
|
-
- HY-10119A
-
|
SCH 530348 sulfate
|
Protease Activated Receptor (PAR)
|
Cardiovascular Disease
|
|
Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
|
-
- HY-W009425R
-
|
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
N,N-Diethyl-p-phenylenediamine Sulfate (Standard) is the analytical standard of N,N-Diethyl-p-phenylenediamine Sulfate. This product is intended for research and analytical applications. N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W749873
-
-
- HY-W094709
-
-
- HY-A0199
-
-
- HY-104026S5
-
-
- HY-19399B
-
|
(-)-BRX 005 sulfate; (-)-BRX 235 sulfate
|
p38 MAPK
HSP
|
Cardiovascular Disease
|
|
Iroxanadine (BRX 005) sulfate is a vasculoprotector. Iroxanadine is a p38 kinase and HSP protein dual activator. Iroxanadine sulfate has the potential for atherosclerosis and vascular diseases research .
|
-
- HY-W674241
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
4-Ethylphenyl sulfate is a gut microbial metabolite. 4-Ethylphenyl sulfate is also a protein-bound uremic toxin, a xenobiotic substrate, and causes endothelial dysfunction .
|
-
- HY-W674241A
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
4-Ethylphenyl sulfate sodium is a gut microbial metabolite. 4-Ethylphenyl sulfate sodium is also a protein-bound uremic toxin, a xenobiotic substrate, and causes endothelial dysfunction .
|
-
- HY-108307
-
|
Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate
|
Antibiotic
Bacterial
|
Infection
|
|
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .
|
-
- HY-B0441A
-
|
Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .
|
-
- HY-W099535
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lithium dodecyl sulfate is an anionic detergent and surfactant that can be used in place of SDS for electrophoresis under low temperatures. Lithium dodecyl sulfate can be used for synthesis of nanomaterials and chromatography .
|
-
- HY-W096997S
-
|
Sodium octyl sulfate
|
Isotope-Labeled Compounds
|
Others
|
|
Sodium octyl sulfate(Reagent for Ion-Pair Chromatography,99%)-d17 is the deuterium labeled Sodium octyl sulfate(Reagent for Ion-Pair Chromatography,99%)[1].
|
-
- HY-Y0317E
-
|
Disodium sulfate (Pharmaceutical primary standard, USP)
|
Biochemical Assay Reagents
|
Others
|
|
Sodium sulfate anhydrous (Disodium sulfate), can be widely used as a desiccant, pH regulator, etc. in biochemical experiments. It is a reference standard grade of the United States Pharmacopeia (USP), pharmaceutical primary standard.
|
-
- HY-15498A
-
|
BMS-927711 sulfate hydrate; BHV-3000 sulfate hydrate
|
CGRP Receptor
|
Neurological Disease
|
|
Rimegepant (sulfate hydrate) is an orally active, selective and competitive calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki of 0.027 nM. Rimegepant (sulfate hydrate) can be used in migraine related research .
|
-
- HY-A0272
-
-
- HY-W094350
-
|
Gypsum fibrosum (99%)
|
Biochemical Assay Reagents
|
Others
|
|
Calcium sulfate dihydrate (99%) (Gypsum fibrosum (99%)) is a desiccant. Calcium sulfate dihydrate (99%) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-79457
-
|
|
NO Synthase
HSV
|
Infection
Inflammation/Immunology
|
|
S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock .
|
-
- HY-Y1881B
-
|
|
Biochemical Assay Reagents
Reactive Oxygen Species (ROS)
MyD88
SOD
Caspase
|
Others
|
|
Copper sulfate pentahydrate, for cell culture, 98% is a biochemical reagent. Copper sulfate pentahydrate, for cell culture, 98% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, for cell culture, 98% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, for cell culture, 98% is cytotoxic to various cells .
|
-
- HY-B1154R
-
|
(-)-Terbuclomine (Standard)
|
Reference Standards
Adrenergic Receptor
5-HT Receptor
|
Neurological Disease
|
|
Penbutolol (sulfate) (Standard) is the analytical standard of Penbutolol (sulfate). This product is intended for research and analytical applications. Penbutolol sulfate ((-)-Terbuclomine) is a potent β-adrenoceptor and 5-HT receptor antagonist with Ki of 11.6 nM and 11.9 nM for 5-HT in rat cornu ammonis 1 (CA1) and human CA3 .
|
-
- HY-16955A
-
|
ACHN 490 sulfate
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Plazomicin (ACHN 490) sulfate is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin sulfate is against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin sulfate has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .
|
-
- HY-B0470
-
|
|
Bacterial
Antibiotic
Phospholipase
|
Infection
Cancer
|
|
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .
|
-
- HY-101406
-
-
- HY-W284558
-
-
- HY-B0394S
-
|
Tropine tropate-d5; DL-Hyoscyamine-d5
|
mAChR
Autophagy
|
Neurological Disease
|
|
Atropine-d5 is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect .
|
-
- HY-137318
-
|
|
Others
|
Metabolic Disease
|
|
BM 15766 sulfate is an inhibitor of 7-dehydrocholesterol δ7-reductase and reduces plasma cholesterol levels. BM 15766 sulfate is a hypolipidemic agent .
|
-
- HY-114231C
-
|
ELX-02 sulfate; NB-124 sulfate
|
Others
|
Metabolic Disease
|
|
Exaluren (ELX-02) sulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). Exaluren sulfate is being developed as a therapy for genetic diseases caused by nonsense mutations .
|
-
- HY-Y0317IR
-
|
Disodium sulfate, meets analytical specification of Ph. Eur. BP USP (Standard)
|
Reference Standards
Biochemical Assay Reagents
|
Others
|
|
Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP (Standard) is the analytical standard of Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP. This product is intended for research and analytical applications. Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
|
-
- HY-B0689A
-
|
MK-639; L735524
|
HIV
HIV Protease
SARS-CoV
Apoptosis
MMP
|
Infection
Cancer
|
|
Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CL pro inhibitor .
|
-
- HY-14915A
-
|
MN-221; KUR-1246
|
Adrenergic Receptor
|
Inflammation/Immunology
|
|
Bedoradrine (MN-221) sulfate is a highly selective β2-adrenergic receptor agonist. Bedoradrine sulfate can effectively relieve airway spasm in asthma patients, dilate airway smooth muscle cells, reduce airway inflammation, and thus improve respiratory function. Bedoradrine sulfate can be used in research on asthma treatment .
|
-
- HY-B0956
-
|
Aminosidine sulfate
|
Antibiotic
Parasite
Bacterial
|
Infection
|
|
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .
|
-
- HY-N0471C
-
|
Daturine sulfate hydrate
|
mAChR
|
Neurological Disease
|
|
L-Hyoscyamine sulfate hydrate, a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate hydrate is a levo-isomer to Atropine (HY-B1205) .
|
-
- HY-W094464
-
-
- HY-B0802
-
|
Terbutaline hemisulfate
|
Adrenergic Receptor
Antibiotic
|
Endocrinology
|
|
Terbutaline sulfate is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol . Terbutaline sulfate can be used in asthma symptom research .
|
-
- HY-111355B
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholesteryl sulfate sodium is an orally available, NPC2-targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis (EC50=50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation .
|
-
- HY-148682
-
|
Glycyrrhetic acid 3-O-hydrogen sulfate
|
OAT
11β-HSD
Drug Metabolite
|
Metabolic Disease
Inflammation/Immunology
|
|
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research .
|
-
- HY-158221
-
|
CSMA
|
Biochemical Assay Reagents
|
Others
|
Chondroitin Sulfate Methacryloyl (CSMA) is methacrylated chondroitin sulfate and is biocompatible. Chondroitin Sulfate Methacryloyl has a higher degree of methacrylation than HAMA (HY-158220), and the degree of methacrylation is closely related to customizable mechanical properties, swelling properties and enzymatic degradability. Chondroitin Sulfate Methacryloyl is a versatile biomaterial suitable for biomimetic hydrogel scaffolds and an ideal 3D printing hydrogel ink . Chondroitin Sulfate Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.
|
-
- HY-W106012
-
-
- HY-W706303
-
-
- HY-W019901B
-
|
Gypsum ustum (97%)
|
Biochemical Assay Reagents
|
Others
|
|
Anhydrous calcium sulfate (97%) (Gypsum ustum (97%)) can be used in medical materials. Anhydrous calcium sulfate (97%) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-A0155B
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Viomycin sulfate hydrate is a potent antibiotic against Mycobacteria. Viomycin sulfate hydrate rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis .
|
-
- HY-113155A
-
|
|
Drug Intermediate
|
Neurological Disease
|
|
17-Hydroxypregnenolone sulfate sodium is a key brain-penetrant intermediate in adrenal and gonadal steroidogenesis. 17-Hydroxypregnenolone sulfate sodium acts as a precursor in the biosynthesis of steroid hormones (e.g., glucocorticoids, sex hormones). 17-Hydroxypregnenolone sulfate sodium is promising for research of adrenal function development and neurosteroid-related diseases (e.g., cognitive impairment, neurodegenerative diseases) .
|
-
- HY-17566
-
|
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
Metabolic Disease
|
|
Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease .
|
-
- HY-B0394
-
|
Tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate
|
mAChR
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
|
-
- HY-Y0316B
-
|
Sodium lauryl sulfate for electrophoresis; Laurylsulfuric acid sodium salt for electrophoresis
|
Biochemical Assay Reagents
|
Others
|
|
Sodium dodecyl sulfate for electrophoresis is a high purity sodium dodecyl sulfate (SDS) with a minimum purity of 98.5%. It is an anionic detergent commonly used in electrophoretic procedures to denature and impart a negative charge to proteins, allowing separation based on size and charge. Sodium dodecyl sulfate for electrophoresis has unique chemical properties that make it an effective ingredient in many laboratory applications, helping to improve the resolution and sensitivity of protein analysis.
|
-
- HY-B1205A
-
|
Tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol
|
mAChR
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
|
-
- HY-A0248C
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Polymyxin B2 Sulfate is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 Sulfate kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 Sulfate can be used in antibiotic development and treatment of drug-resistant strains .
|
-
- HY-10202B
-
|
|
FLT3
c-Kit
PDGFR
Apoptosis
|
Cancer
|
|
Tandutinib (MLN518) sulfate is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib sulfate can be used for acute myelogenous leukemia (AML) . Tandutinib sulfate has the ability to cross the blood-brain barrier .
|
-
- HY-W019927
-
|
Ammonium ferric sulfate dodecahydrate, 99%
|
Biochemical Assay Reagents
|
Others
|
|
Ammonium iron(Ⅲ) sulfate dodecahydrate, 99% is a biochemical reagent. Ammonium iron(Ⅲ) sulfate dodecahydrate, 99% is often used as a source material for the reagent solution or the standard solution of iron(III) .
|
-
- HY-148682S2
-
|
Glycyrrhetic acid 3-O-(hydrogen sulfate)-d3
|
Isotope-Labeled Compounds
|
Others
|
|
18β-Glycyrrhetyl-3-O-sulfate-d3 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682) .
|
-
- HY-W094475D
-
|
Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
|
Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC is currently the anticonvulsant of choice for the prevention and control of eclamptic fits. Magnesium sulfate is also widely used as a tocolytic agent .
|
-
- HY-45609
-
|
|
iGluR
Endogenous Metabolite
|
Neurological Disease
|
|
L-Cysteine S-sulfate sodium hydrate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist. L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry operations .
|
-
- HY-148682S1
-
|
Glycyrrhetic acid 3-O-(hydrogen sulfate)-d2
|
Isotope-Labeled Compounds
|
Others
|
|
18β-Glycyrrhetyl-3-O-sulfate-d2 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682) .
|
-
- HY-B2162
-
|
Chondroitin polysulfate
|
NO Synthase
MMP
Endogenous Metabolite
|
Inflammation/Immunology
Cancer
|
|
Chondroitin sulfate, one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs.
|
-
- HY-100401A
-
|
CS-505
|
Acyltransferase
|
Cardiovascular Disease
|
|
Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively . Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity .
|
-
- HY-116282C
-
|
DSS (MW 35000-45000); DXS (MW 35000-45000)
|
Apoptosis
|
Infection
Inflammation/Immunology
|
|
Dextran sulfate sodium salt (DSS) (MW 35000-45000) is a polymer of dehydrated glucose with a molecular weight of approximately 35000-45000. DSS with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (DSS) (MW 35000-45000) is a potent inducer of colitis. Dextran sulfate sodium salt (DSS) (MW 35000-45000) can be used to induce model acute colitis, chronic colitis, and colitis-related colon cancer. Dextran sulfate sodium salt (DSS) (MW 35000-45000) may be related to macrophage dysfunction, intestinal flora dysbiosis, and is particularly toxic to the colonic epithelium .
|
-
- HY-129065
-
|
Streptothricin sulfate
|
Fungal
Bacterial
Antibiotic
|
Infection
|
|
Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that destroys the outer membrane of Gram-negative bacteria and is a dominant selective marker for Fonsecaea pedrosoi . Nourseothricin sulfate inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi and can also be used as a elective marker for a wide range of organisms including bacteria, yeast, filamentous fungi, and plant cells .
|
-
- HY-B0689B
-
|
MK-639 ethanolate; L735524 ethanolate
|
Apoptosis
MMP
HIV
HIV Protease
SARS-CoV
|
Infection
Cancer
|
|
Indinavir sulfate ethanolate (MK-639 ethanolate) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir sulfate ethanolate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate ethanolate is also a SARS-CoV 3CL pro inhibitor .
|
-
- HY-108314A
-
-
- HY-W010973
-
-
- HY-B1083
-
-
- HY-B1581A
-
|
|
NO Synthase
|
Cancer
|
|
L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.
|
-
- HY-100920
-
-
- HY-108314
-
-
- HY-N7065
-
-
- HY-120098A
-
|
|
Others
|
Cancer
|
|
Vinleurosine sulfate is an indole alkaloid with antineoplastic activity .
|
-
- HY-B0472
-
-
- HY-100787
-
|
|
iGluR
Endogenous Metabolite
|
Neurological Disease
|
|
L-Cysteine S-sulfate sodium is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist. L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry operations .
|
-
- HY-113084
-
|
|
iGluR
Endogenous Metabolite
|
Neurological Disease
|
|
L-Cysteine S-sulfate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptor agonist. L-Cysteine S-sulfate is the substrate for cystine lyase, and can be used in mass spectrometry operations .
|
-
- HY-B0089A
-
|
Bay-g 5421 sulfate
|
Glycosidase
|
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Acarbose (BAY g 5421) sulfate, antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose sulfate can potentiate the hypoglycemic effects of sulfonylureas or insulin .
|
-
- HY-153993
-
|
|
Endogenous Metabolite
|
Others
|
|
Pyrocatechol sulfate, a phenolic metabolite present in human plasma, is associated with the consumption of specific foods such as berries and the condition of gut microbiota. It serves as a potential urinary biomarker for kidney function, dialytic clearance, whole grain consumption, and regular coffee intake. Additionally, Pyrocatechol sulfate, along with other phenolic sulfates, plays a role in modulating various biological functions, including those related to brain health and the rhythmic beating of cardiomyocytes.
|
-
- HY-113293B
-
|
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Cancer
|
|
Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). Estrone sulfate can be used for the research of breast cancer .
|
-
- HY-W501565
-
-
- HY-W587959
-
-
- HY-113293A
-
-
- HY-149466
-
-
- HY-124704
-
|
|
SULT
|
Neurological Disease
|
|
Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair .
|
-
- HY-23120
-
|
|
Antibiotic
Virus Protease
|
Infection
Cancer
|
|
1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity .
|
-
- HY-10962
-
|
CYT387 sulfate salt
|
JAK
Autophagy
Apoptosis
|
Cancer
|
|
Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).
|
-
- HY-168573
-
|
|
BCRP
|
Cancer
|
|
AZ99 (compound 7) is a potent ABCG2 inhibitor. AZ99 inhibits ABCG2-mediated transport of estrone-3-sulfate (E1S) into proteoliposomes and ABCG2 ATPase activity .
|
-
- HY-B1228
-
|
Vistamycin sulfate
|
Bacterial
Antibiotic
PDI
|
Infection
|
|
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies
|
-
- HY-12279B
-
|
TGR-1202 sulfate; RP-5264 sulfate
|
PI3K
Casein Kinase
|
Cancer
|
|
Umbralisib (TGR-1202) sulfate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib sulfate exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib sulfate can be used for haematological malignancies reseach .
|
-
- HY-172549
-
-
- HY-131150
-
-
- HY-W328317
-
-
- HY-137932
-
-
- HY-A0276
-
|
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM .
|
-
- HY-B1329
-
|
Nebramycin II sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .
|
-
- HY-Y1083H
-
|
Salt of lemery, 99%
|
Biochemical Assay Reagents
|
Others
|
|
Potassium sulfate, 99% (Salt of lemery, 99%) can be used in biochemical tests for serum proteins, the determination of blood potassium and other potassium salts, and the preparation of protein capillary electrophoresis buffers. Potassium sulfate, 99% is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-Y0945B
-
-
- HY-D0745
-
|
|
Fluorescent Dye
|
|
|
Acid red 405 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-W742957
-
|
|
iGluR
|
Neurological Disease
|
|
Pregnanolone sulfate pyridinium is an endogenous neurosteroid that inhibits NMDA receptors and is neuroprotective .
|
-
- HY-D0613
-
|
|
Fluorescent Dye
|
|
|
Acid Red 337 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-D0398
-
|
|
Fluorescent Dye
|
|
|
Acid red 42 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-115762
-
-
- HY-D0660
-
|
|
Fluorescent Dye
|
|
|
Acid red 131 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-D1209
-
|
|
Fluorescent Dye
|
|
|
Acid Red 35 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-B2162A
-
|
Chondroitin polysulfate sodium (from shark cartilage)
|
NO Synthase
MMP
Endogenous Metabolite
|
Inflammation/Immunology
Cancer
|
|
Chondroitin sulfate sodium (from shark cartilage), one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs .
|
-
- HY-Y1083C
-
|
Salt of lemery, for cell culture
|
Biochemical Assay Reagents
|
Others
|
|
Potassium sulfate, for cell culture (Salt of lemery, for cell culture) can be used in biochemical tests for serum proteins, the determination of blood potassium and other potassium salts, and the preparation of protein capillary electrophoresis buffers. Potassium sulfate, for cell culture is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-116441
-
|
|
Drug Metabolite
|
Neurological Disease
|
|
4-Hydroxy-3-methoxyamphetamine hydrochloride is a metabolite of 3,4-Methylenedioxymethamphetamine (MDMA). 4-Hydroxy-3-methoxyamphetamine hydrochloride can be used for forensic analysis .
|
-
- HY-W011910
-
-
- HY-W792683
-
|
|
Others
|
Others
|
|
Homovanillic Acid Sulfate is a Phenols product that can be isolated from From olive oil. .
|
-
- HY-157348
-
-
- HY-B1206
-
-
- HY-107027
-
|
|
Antibiotic
|
Infection
|
|
Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa .
|
-
- HY-N3513
-
|
Kuwanon C
|
OAT
|
Cardiovascular Disease
|
|
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8?±1.5 μM.
|
-
- HY-50859
-
|
INCB018424 sulfate
|
JAK
Autophagy
|
Cancer
|
|
Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.
|
-
- HY-P2727
-
|
ChABC
|
Endogenous Metabolite
|
Neurological Disease
Inflammation/Immunology
|
|
Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury .
|
-
- HY-75385A
-
|
CDP323 sulfate; UCB1184197 sulfate
|
Integrin
|
Inflammation/Immunology
|
|
Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester proagent of CT7758 , is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders .
|
-
- HY-113152
-
|
|
Endogenous Metabolite
|
Others
|
|
Hypogeic acid can be isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters .
|
-
- HY-W195048
-
-
- HY-W775100
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Spectinomycin sulfate is an aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity .
|
-
- HY-W103170
-
|
|
Bacterial
|
Others
|
|
1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .
|
-
- HY-W019976
-
-
- HY-N1523
-
|
Cleroindicin A
|
Others
|
Neurological Disease
|
|
Rengyol (Cleroindicin A), a natural alcohol compound, is an inhibitor of emesis induced by copper sulfate pentahydrate .
|
-
- HY-N0675A
-
|
|
Microtubule/Tubulin
|
Cancer
|
|
Anhydrovinblastine sulfate is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves .
|
-
- HY-B1018A
-
-
- HY-50706AR
-
|
|
MEK
Apoptosis
|
Cancer
|
|
Selumetinib (sulfate) (Standard) is the analytical standard of Selumetinib (sulfate). This product is intended for research and analytical applications. Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.
|
-
- HY-W019832
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Glucosamine 3-sulfate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-A0086
-
|
SCH-20569 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Netilmicin (Sch 20569) sulfate is a broad-spectrum semisynthetic aminoglycoside antibiotic. Netilmicin sulfate exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL .
|
-
- HY-Y0316
-
|
Sodium lauryl sulfate; Laurylsulfuric acid sodium salt
|
Biochemical Assay Reagents
|
Others
|
|
Sodium dodecyl sulfate is an anionic surfactant commonly used as a detergent, emulsifier, and protein denaturant in various industrial processes, especially in the production of personal care products, cleaners, and laboratory reagents. Sodium dodecyl sulfate has unique chemical properties that make it an effective ingredient in many applications, helping to reduce surface tension and enhance cleaning power.
|
-
- HY-Y0261A
-
-
- HY-169798
-
|
|
Fluorescent Dye
|
Others
|
|
1,9-Dimethylmethylene blue is a fluorescent dye that can be used for detection of sulfated glycosaminoglycans .
|
-
- HY-19806A
-
|
CXA-101; FR264205
|
Bacterial
|
Infection
|
|
Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. Ceftolozane binds to P. aeruginosa essential PBPs (1b, 1c, 2 and 3) with high affinity. Ceftolozane inhibits cell wall synthesis by binding the PBPs. Ceftolozane sulfate inhibits P. aeruginosa and Enterobacteriaceae .
|
-
- HY-Y0317H
-
|
Disodium sulfate, for cell culture
|
Biochemical Assay Reagents
|
Cancer
|
|
Sodium sulfate anhydrous, for cell culture is a drying agent in organic synthesis, which can be used for cell culture .
|
-
- HY-W127367
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sodium eicosyl sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B1304A
-
|
(+)-Lupinidine sulfate pentahydrate
|
nAChR
|
Neurological Disease
|
|
(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons .
|
-
- HY-W096994A
-
|
Tetramethylammonium sulphate
|
Biochemical Assay Reagents
|
Others
|
|
Tetramethylammonium sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-137513
-
|
|
Biochemical Assay Reagents
|
|
|
N-Acetyl-D-glucosamine 6-sulfate (sodium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
|
-
- HY-B1329R
-
|
Nebramycin II sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
|
-
- HY-W110772
-
|
Coumarin 540A
|
Fluorescent Dye
|
Others
|
|
Coumarin153 is a coumarin. Coumarin153 can used as a fluorescence probe of Na dodecyl sulfate and cetyltrimethylammonium bromide .
|
-
- HY-114603A
-
|
LY 294468 sulfate
|
Thrombin
|
Cardiovascular Disease
|
|
Efegatran (LY 294468) sulfate is an inhibitor for thrombin, which inhibits aggregation of platelets, and exhibits anticoagulant and antithrombotic activities .
|
-
- HY-W127623
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tris Dodecyl Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-137847
-
-
- HY-W010668
-
|
|
Flavivirus
Dengue Virus
Parasite
Potassium Channel
|
Others
|
|
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM .
|
-
- HY-16566A
-
|
Kanamycin A sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
|
-
- HY-W754114
-
-
- HY-145530
-
-
- HY-137208
-
|
|
Drug Metabolite
|
Inflammation/Immunology
|
|
Chondroitin disaccharide Δdi-0S sodium is an unsaturated disaccharide produced by the degradation of Chondroitin sulfate (HY-B2162). Chondroitin disaccharide Δdi-0S sodium produces fluorescent pyridylamino derivative with 2-aminopyridine, which can be used in studies about the metabolic pathway of Chondroitin sulfate and related disease mechanisms .
|
-
- HY-B2162D
-
|
Chondroitin polysulfate sulfate (from chicken)
|
Biochemical Assay Reagents
|
Others
|
|
Chondroitin sulfate from Chicken is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W927849
-
|
Magnesium lauryl sulfate
|
Biochemical Assay Reagents
|
Others
|
|
Magnesium dodecyl sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-130072
-
|
|
Fungal
|
Cancer
|
|
Bivittoside B is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal and potential antitumor activities.
|
-
- HY-130047
-
|
|
Fungal
|
Cancer
|
|
Bivittoside A is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal properties and potential for antitumor applications.
|
-
- HY-B2162C
-
|
Chondroitin polysulfate sulfate (from pig)
|
Biochemical Assay Reagents
|
Others
|
|
Chondroitin sulfate from Pig is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B2162B
-
|
Chondroitin polysulfate sulfate sodium (from bovine)
|
Biochemical Assay Reagents
|
Others
|
|
Chondroitin sulfate from Bovine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B0755
-
|
|
Antibiotic
|
Infection
|
|
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.
|
-
- HY-129977
-
-
- HY-113293
-
-
- HY-N3513R
-
|
Kuwanon C (Standard)
|
Reference Standards
Others
|
Cardiovascular Disease
|
|
Mulberrin (Standard) is the analytical standard of Mulberrin. This product is intended for research and analytical applications. Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
|
-
- HY-109075A
-
|
|
Adrenergic Receptor
|
Neurological Disease
|
|
Tasipimidine sulfate is an orally active and selective α2A-adrenoceptor agonist with a pEC50 of 7.57 for human α2A-adrenoceptors and an EC50 of 5.7 nM for rat α2-adrenoceptor. Tasipimidine sulfate can be utilized in research related to situational anxiety and fear .
|
-
- HY-18754A
-
|
FR 167653 sulfate
|
p38 MAPK
Autophagy
|
Endocrinology
|
|
FR 167653 (FR 167653 sulfate), an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 (FR 167653 sulfate) is effective in treating inflammation, relieving trauma and ischemia-reperfusion injury in vivo .
|
-
- HY-113263
-
|
|
Endogenous Metabolite
|
Endocrinology
|
|
17a-Hydroxypregnenolone is an intermediate in the synthesis of steroid hormones and may be related to the synthesis of sex hormones or adrenal hormones. The sulfate form of 17a-Hydroxypregnenolone (17α-hydroxypregnenolone sulfate) is the main interfering substance in neonatal plasma, which can significantly affect the immunoassay results of 17α-hydroxyprogesterone (17-OHP) by cross-reacting with antibodies .
|
-
- HY-B1174A
-
|
Kanamycin B sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
Bekanamycin (Kanamycin B) sulfate is a minor component of the kanamycin complex, an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus, with antibacterial activity .
|
-
- HY-120206B
-
|
BMS-204756 sulfate
|
Monoamine Oxidase
|
Neurological Disease
|
|
Brasofensine (BMS-204756) sulfate is an oral active dopamine transporter antagonist and can be used for parkinson’s disease research .
|
-
- HY-148375
-
|
|
Drug Metabolite
|
Others
|
|
Abiraterone sulfate is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity .
|
-
- HY-113415
-
-
- HY-W110917
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dimethylsulfonazo III is a potent sulfate indicator. Dimethylsulfonazo III can be used as indicator to test those samples contaminated with potassium or phosphate ions .
|
-
- HY-150520
-
|
|
Antibiotic
|
Infection
Cancer
|
|
Neomycin is an aminoglycoside antibiotic. Neomycin can be used for the research of external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt .
|
-
- HY-15954B
-
-
- HY-P2953
-
|
Heparinase III
|
Biochemical Assay Reagents
|
Others
|
|
Heparitin sulfate lyase (Heparinase III) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-77026
-
-
- HY-B2162E
-
|
Chondroitin polysulfate (from shark cartilage)
|
Biochemical Assay Reagents
|
Others
|
|
Chondroitin sulfate (from shark cartilage) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W130648
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sodium 2-ethylhexyl sulfate (40% in water) is an anionic surfactant commonly used as a detergent, wetting agent, and emulsifier in various industrial processes, especially in the production of personal care products, cleaning agents, and textile auxiliaries. Sodium 2-ethylhexyl sulfate (40% in water) has unique chemical properties that make it an effective ingredient in many applications, helping to reduce surface tension and enhance cleaning power.
|
-
- HY-16094
-
|
BW 467C60
|
Adrenergic Receptor
|
Neurological Disease
|
|
Bethanidine sulfate and its ortho-chloro derivative (BW 392C60) are potent adrenergic neurone blockers with sympathomimetic effects similar to bretylium and guanethidine in various animal models, particularly in cats. They inhibit the release of noradrenaline during nerve stimulation and enhance smooth muscle responses to adrenaline and noradrenaline. Bethanidine sulfate increases pressor responses to tyramine, though this effect diminishes with higher doses. Unlike guanethidine, Bethanidine sulfate does not deplete pressor amine content in the iris of cats post-administration. It also briefly inhibits autonomic cholinergic mechanisms and causes temporary neuromuscular paralysis in large doses, contrasting with its prolonged adrenergic neurone blocking effects .
|
-
- HY-120206A
-
|
BMS-204756 maleate
|
Monoamine Oxidase
|
Neurological Disease
|
|
Brasofensine maleate(BMS-204756) sulfate is an oral active dopamine transporter antagonist and can be used for parkinson’s disease research .
|
-
- HY-118774
-
-
- HY-Y0317I
-
|
Disodium sulfate, meets analytical specification of Ph. Eur. BP USP
|
Biochemical Assay Reagents
|
Others
|
|
Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
|
-
- HY-122307
-
|
DAN-603
|
Bacterial
|
Metabolic Disease
|
|
Sulisatin (DAN-603) is an anionic laxative that is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon during oral administration .
|
-
- HY-101900
-
|
Nile blue sulfate
|
Fluorescent Dye
|
Others
|
|
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
|
-
- HY-P2123A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria .
|
-
- HY-B0560A
-
|
|
Biochemical Assay Reagents
|
|
|
Ammonium aluminum sulfate dodecahydrate is a biomolecule precipitation agent that can change the solubility of proteins by interacting with water molecules, thereby effectively purifying proteins.
|
-
- HY-W739789
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(6R)-Tetrahydro-L-biopterin (sulfate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-113305
-
-
- HY-A0089
-
|
Polymyxin E sulfate
|
Bacterial
Autophagy
Antibiotic
|
Infection
|
|
Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
|
-
- HY-W145672
-
|
|
Biochemical Assay Reagents
|
Others
|
|
D-Galactose-4-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-107911
-
|
|
Thrombin
|
Metabolic Disease
|
|
Protamine sulfate, polycationic peptide and a antiheparin agent, could neutralize the anticoagulant action of heparin and enhances lipid-mediated gene transfer .
|
-
- HY-19857
-
-
- HY-B0172B
-
|
|
Endogenous Metabolite
|
Endocrinology
|
|
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .
|
-
- HY-W009425
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W145673
-
|
D-Galactose-6-O-sulphate sodium salt
|
Biochemical Assay Reagents
|
Others
|
|
D-Galactose-6-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-141692A
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
IL-17 modulator 4 sulfate is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. IL-17 modulator 4 sulfate is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome .
|
-
- HY-W698571
-
|
4-O-(3-O-Sulfo-β-D-galactopyranosyl)-D-glucose
|
Biochemical Assay Reagents
|
Others
|
|
Lactose-3'-sulfate (4-O-(3-O-Sulfo-β-D-galactopyranosyl)-D-glucose) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-N0488
-
|
Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate
|
Microtubule/Tubulin
Apoptosis
|
Cancer
|
|
Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
|
-
- HY-104026B
-
-
- HY-160216A
-
|
|
RIP kinase
|
Inflammation/Immunology
|
|
RIPK1-IN-18 sulfate hydrate is a potent RIPK1 inhibitor that can be used in autoimmune diseases research (NZ748385A; compound i) .
|
-
- HY-148083
-
|
|
Drug Metabolite
PPAR
|
Metabolic Disease
|
|
TBBPA-sulfate is metabolite of TBBPA. TBBPA has been reported to enhance adipogenesis by binding with the peroxisome proliferator-activated receptor gamma (PPARγ) .
|
-
- HY-162588
-
-
- HY-164416
-
|
|
Drug Intermediate
|
Inflammation/Immunology
|
|
DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .
|
-
- HY-113441
-
|
MHPG sulfate potassium
|
Biochemical Assay Reagents
|
Others
|
|
4-Hydroxy-3-methoxyphenylglycol sulfate potassium is a biosynthesis product that releases Na2SO4 and free ethylene glycol on acidic hydrolysis .
|
-
- HY-101238
-
-
- HY-157357
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fungi Agar Medium can be used in sterile growth tests. Fungi Agar Medium ingredients include peptone, glucose, yeast powder, potassium dihydrogen phosphate, magnesium sulfate, and agar.
|
-
- HY-W748456
-
|
|
Others
|
Others
|
|
Apigenin-7-O-sulfate is a major flavonoid which is found to be a distinctive feature of plants from the Bay of Cadiz and can be extracted from these plants .
|
-
- HY-W145694
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Acetyl-D-galactosamine-4-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-N0430A
-
-
- HY-W744419
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Epiandrosterone sulfate sodium salt-d5 is the deuterium labeled Sodium (3S,5S,8R,9S,10S,13S,14S)-10,13-dimethyl-17-oxohexadecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfate (HY-W707903).
|
-
- HY-16765A
-
|
TD-1211 sulfate
|
Opioid Receptor
|
Neurological Disease
|
|
Axelopran sulfate is an opioid receptor antagonist with pKi values of 9.8, 8.8 and 9.9 for human recombinant μ and δ receptors and guinea pig κ receptor, respectively.
|
-
- HY-17567
-
-
- HY-122307A
-
|
DAN-603 disodium
|
Bacterial
|
Metabolic Disease
|
|
Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon .
|
-
- HY-149049
-
|
Cajanine
|
HCV
|
Infection
Inflammation/Immunology
|
|
Cajaninstilbene acid is a potent HCV inhibitor with an IC50 of 3.17 μM. Cajaninstilbene acid inhibits HCV replications via down-regulates a cellular protein chondroitin sulfate N-acetylgalactosaminyltransferase 1 .
|
-
- HY-121360
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Cylindrospermopsin is a cyanotoxin produced by a variety of freshwater cyanobacteria. It is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA .
|
-
- HY-N6665
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Cefquinome sulfate is a broad-spectrum cephem antibiotic that has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, including Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae .
|
-
- HY-123063
-
|
5α-Petromyzonol; 5α-PZ
|
Endogenous Metabolite
|
Others
|
|
Petromyzonol (5α-Petromyzonol) is a tetrahydroxy stearol produced by the bile of sea lamprey larvae from the bile acid precursor acetylcholic acid. Petromyzonol sulfate acts as a pheromone and oviposition chemical attractant .
|
-
- HY-17561
-
|
Geneticin sulfate; Antibiotic G-418 sulfate
|
Bacterial
Antibiotic
|
Infection
|
|
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .
|
-
- HY-B0639C
-
|
WR2721 sodium
|
MDM-2/p53
HIF/HIF Prolyl-Hydroxylase
|
Neurological Disease
|
|
Amifostine sodium (WR2721 sodium) is a phosphorus sulfate with radioprotective activity. Amifostine sodium can cause splenic vasodilation and may block autonomic ganglia. Amifostine sodium is clinically used to prevent cisplatin-induced ototoxicity .
|
-
- HY-W653718
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
o-Cresol-d7 is the deuterium labeled o-Cresol (HY-156199). o-Cresol sulfate is a biomarker related to CAR T cell-independent and dependent metabolic and inflammatory .
|
-
- HY-D0241
-
|
Variamine Blue RT sulfate
|
Fluorescent Dye
|
Others
|
|
4-Aminodiphenylamine sulfate (Variamine Blue RT sulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-108622
-
-
- HY-W068581
-
|
|
Drug Intermediate
|
Others
|
|
(S)-3-Amino-2,2-dimethyl-4-oxoazetidin-1-yl hydrogen sulfate is a drug intermediate for synthesis of various active compounds.
|
-
- HY-168626A
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 252 hydrochloride is an amino acid derivative with antibacterial activity. Antibacterial agent 252 hydrochloride enhances the killing of colistin sulfate (HY-A0089) against a variety of gram-negative bacteria by targeting the bacterial membrane .
|
-
- HY-N15142
-
|
|
Others
|
Others
|
|
Furcellaran is an anionic sulfated polysaccharide obtained from red algae. Furcellaran inhibits ice recrystallization as effectively as κ-Carrageenan (HY-138962). Furcellaran is promising for research of edible film production .
|
-
- HY-Y0261AS
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Ammonium sulphate-d8 is the deuterium labeled Ammonium sulphate,≥99.0%,AR . Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology .
|
-
- HY-157370
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Blood Enrichment Medium can be used for enrichment culture of pathogenic bacteria in blood. Blood Enrichment Medium ingredients include peptone, beef extract powder, NaCl, glucose, sodium citrate, para-aminobenzoic acid, magnesium sulfate, phenol red .
|
-
- HY-P3160
-
|
|
Integrin
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
|
-
- HY-B0172BR
-
|
|
Reference Standards
Endogenous Metabolite
|
Endocrinology
|
|
Isolithocholic acid (Standard) is the analytical standard of Isolithocholic acid. This product is intended for research and analytical applications. Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2].
|
-
- HY-W338810S
-
-
- HY-B1154
-
-
- HY-157367
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bismuth Sulfite Agar Medium can be used for selective isolation and culture of Salmonella. Bismuth Sulfite Agar Medium ingredients include tryptone, peptone, beef powder, ferrous sulfate, bismuth sulfite, disodium hydrogen phosphate, glucose, brilliant green, agar .
|
-
- HY-100898
-
|
|
Glycosidase
|
Cancer
|
|
OGT 2115 is a potent, cell-permeable and orally active heparanase inhibitor with an IC50 of 0.4 μM. OGT 2115 has anti-angiogenic properties (IC50 of 1 μM). OGT 2115 also inhibits heparan sulfate degradation activity .
|
-
- HY-15781
-
|
|
Bacterial
|
Infection
|
|
Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
|
-
- HY-Y0261AS1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Ammonium sulphate,≥99.0%,AR- 15N2 is the deuterium labeled Ammonium sulphate,≥99.0%,AR . Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology .
|
-
- HY-B2241A
-
|
Aluminum potassium sulfate dodecahydrate, for cell culture
|
Biochemical Assay Reagents
|
Others
|
|
Potassiumalum, for cell culture (Aluminum potassium sulfate dodecahydrate, for cell culture) is an egg white adjuvant that can induce allergic reactions in mice; it can also be used for bacterial staining. Potassiumalum, for cell culture is a biomaterial or organic compound that can be used in life science research .
|
-
- HY-126996
-
|
|
Drug Metabolite
Endogenous Metabolite
|
Metabolic Disease
|
|
Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity .
|
-
- HY-15781A
-
|
|
Bacterial
|
Infection
|
|
(R)-Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. (R)-Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
|
-
- HY-W012836
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine. 4-Ethylphenol is a phenolic compound that can be synthesized by intestinal flora. 4-Ethylphenol will be converted to 4-ethylphenyl sulfate (HY-W674241) by Lactobacillus plantarum .
|
-
- HY-150612
-
|
|
p38 MAPK
|
Cancer
|
|
(R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC50s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis .
|
-
- HY-E70190
-
|
EC:2.8.2.20; TPST2
|
Transmembrane Glycoprotein
|
Metabolic Disease
|
|
Tyrosylprotein Sulfotransferase 2 (TPST-2) is a subtype of TPST. Tyrosylprotein Sulfotransferase is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation of soluble and membrane proteins passing through this compartment .
|
-
- HY-118774R
-
|
|
Reference Standards
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Propofol β-D-glucuronide (Standard) is the analytical standard of Propofol β-D-glucuronide. This product is intended for research and analytical applications. Propofol β-D-glucuronide is a metabolite of Propofol sulfate and can be used for diagnosis to distinguish colorectal cancer from healthy individuals .
|
-
- HY-172486
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-W031727S
-
-
- HY-172484
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG1000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172485A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172485
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-115292
-
|
Tenivastatin sodium; Simvastatin Impurity A sodium
|
HMG-CoA Reductase (HMGCR)
Reactive Oxygen Species (ROS)
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Simvastatin hydroxy acid (Tenivastatin) sodium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin hydroxy acid sodium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin hydroxy acid sodium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-119695B
-
|
Tenivastatin calcium hydrate
|
HMG-CoA Reductase (HMGCR)
Reactive Oxygen Species (ROS)
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Simvastatin acid (Tenivastatin) calcium hydrate is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid calcium hydrate reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid calcium hydrate can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-N0278
-
|
Pulsatilla camphor; Anemonine; trans-Anemonin
|
PKC
NO Synthase
|
Inflammation/Immunology
|
|
Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
|
-
- HY-119695A
-
-
- HY-158403
-
|
|
METTL3
|
Inflammation/Immunology
|
|
METTL3-IN-7 (7460-0250) is a potent METTL3 inhibitor. METTL3-IN-7 strongly ameliorates Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis. METTL3-IN-7 can be used Inflammatory bowel disease (IBD) research .
|
-
- HY-W008992
-
|
8-Hydroxyquinoline sulfate hydrate
|
Biochemical Assay Reagents
|
Others
|
|
Quinolin-8-ol sulfate hydrate is an organic compound commonly used in dyes and as a raw material for chemical analysis. It can cooperate with metal ions to form dyes, and is widely used in the fields of dyes, printing and textile manufacturing. In addition, the compound also has good toxicity and biocompatibility, and is also used in some medical fields.
|
-
- HY-17561R
-
|
Geneticin sulfate (Standard); Antibiotic G-418 sulfate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
G-418 (disulfate) (Standard) is the analytical standard of G-418 (disulfate). This product is intended for research and analytical applications. G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].
|
-
- HY-118704
-
|
|
mTOR
|
Inflammation/Immunology
Cancer
|
|
P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P2281 inhibits mTOR activity in colon cancer cells. P-2281 suppresses Dextran sulfate sodium salt (HY-116282C) (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis .
|
-
- HY-P11101
-
|
|
Biochemical Assay Reagents
|
Others
|
|
plCSA-BP is a Placental CSA-binding peptide. plCSA-BP binds specifically to trophoblasts and not to other cell types in the placenta or to CSA-expressing cells in other tissues. plCSA-BP can guide nanoparticles for the targeted delivery of payloads (such as Indocyanine green (ICG) (HY-D0711) and Methotrexate (MTX) (HY-14519)) to the placenta, promising for placenta-specific drug delivery .
|
-
- HY-W016034
-
|
p-Acetamidophenyl β-D-glucuronide sodium salt; p-AAPG sodium salt
|
Drug Metabolite
|
Infection
|
|
Acetaminophen glucuronide is a safe and effective
antipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liver
and kidney .
|
-
- HY-W016034R
-
|
p-Acetamidophenyl β-D-glucuronide sodium salt (Standard); p-AAPG sodium salt (Standard)
|
Drug Metabolite
Reference Standards
|
Infection
|
|
Acetaminophen glucuronide (sodium salt) (Standard) is the analytical standard of Acetaminophen glucuronide (sodium salt). This product is intended for research and analytical applications. Acetaminophen glucuronide is a safe and effective
antipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liver
and kidney .
|
-
- HY-158404
-
|
|
METTL3
|
Inflammation/Immunology
|
|
METTL3-IN-8 (F039-0002) is a potent METTL3 inhibitor. METTL3-IN-8 strongly ameliorates Dextran sulfate sodium salt (DSS) (HY-116282C)-induced colitis. METTL3-IN-8 can be used Inflammatory bowel disease (IBD) research .
|
-
- HY-Y1092
-
|
|
Biochemical Assay Reagents
Adenylate Cyclase
|
Others
|
|
N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
-
- HY-119695
-
-
- HY-15781R
-
|
|
Bacterial
|
Infection
|
|
Morinidazole (Standard) is the analytical standard of Morinidazole. This product is intended for research and analytical applications. Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N+-glucuronidation and sulfation. Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
|
-
- HY-N0716
-
-
- HY-168567
-
|
|
RIP kinase
NF-κB
p38 MAPK
|
Inflammation/Immunology
|
|
RIPK2-IN-6 (Compound 15a) is an inhibitor for RIPK, that inhibits the phosphorylation of RIPK2, and thus inhibits the NF-κB and MAPK signaling pathways. RIPK2-IN-6 exhibits anti-inflammatory and anti-fibrotic activities in Dextran sodium sulfate (HY-116282C)-induced mice colitis models .
|
-
- HY-W099641
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyltrioctylammonium hydrogen sulfate is a quaternary ammonium salt that is mainly used as an extraction solvent and a phase transfer catalyst in various chemical reactions. It is also used as an electrolyte in electrochemical devices such as batteries and fuel cells, and as a building block for the synthesis of pharmaceuticals and agrochemicals. MTOAHS are multifunctional compounds with many potential industrial applications due to their reactivity, stability, and ability to selectively extract certain compounds from mixtures.
|
-
- HY-14829A
-
|
D-Isofagomine hydrochloride; Isofagomine hydrochloride
|
Glycosidase
|
Metabolic Disease
|
|
Afegostat hydrochloride (D-Isofagomine hydrochloride) is a potent β-galactosidase inhibitor with activity ameliorating GM1-gangliosidosis and Morquio B disease-associated mutations. Afegostat hydrochloride is able to induce the maturation of mutant β-galactosidase in fibroblasts from patients with GM1-gangliosidosis. Afegostat hydrochloride also promotes the reduction of keratin sulfate and oligosaccharide load in patient cells .
|
-
- HY-109006
-
|
|
mAChR
|
Neurological Disease
|
|
Ilmetropium iodide is an anticholinergic agent. Ilmetropium iodide selectively blocks M-cholinergic receptors of bronchial muscle, reduces or prevents bronchoconstrictor response associated with both cholinergic stimulation, as well as the impact of the factors that provoke bronchospasm. Strength and selectivity of ilmetropium iodide action substantially exceeds Atropine sulfate (HY-B1205A) and Ipratropium bromide (HY-B0241) .
|
-
- HY-151252
-
|
|
Proteasome
NOD-like Receptor (NLR)
|
Inflammation/Immunology
|
|
NIC-0102 is an orally active proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammatory vesicle activation. NIC-0102 shows potent anti-inflammatory effects in a model of dextran sulfate sodium (DSS)-induced ulcerative colitis. NIC-0102 also inhibits production of pro-IL-1β .
|
-
- HY-N15207
-
|
|
Others
|
Others
|
|
(3R,5R)-1-(4-Hydroxyphenyl)-7-phenyl-3,5-heptanediol is an antiemetic found in Alpinia officinarum that significantly inhibits copper sulfate-induced emesis in young chicks (with an inhibition rate of 50.9% at a dose of 20 mg/kg and 37.7% at a dose of 50 mg/kg) .
|
-
- HY-W012426
-
|
MDBP
|
Biochemical Assay Reagents
|
Neurological Disease
|
|
1-Piperonylpiperazine (MDBP) is metabolized by demethylenation and subsequent methylation to N-(4-hydroxy-3-methoxybenzyl)piperazine followedby partial glucuronidation or sulfation. 1-Piperonylpiperazine can alter the disposition and metabolism of 3,4-methylenedioxymethamphetamine (MDMA) in the brain and in peripheral organs. 1-Piperonylpiperazine can inhibit the MDMA-induced neurotoxicity .
|
-
- HY-N0278A
-
|
(Rac)-Pulsatilla camphor; (Rac)-Anemonine
|
PKC
NO Synthase
|
Inflammation/Immunology
|
|
(Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases .
|
-
- HY-W753473
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
|
4-Ethylphenol-d9 is the deuterium labeled 4-Ethylphenol (HY-W012836). 4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine. 4-Ethylphenol is a phenolic compound that can be synthesized by intestinal flora. 4-Ethylphenol will be converted to 4-ethylphenyl sulfate (HY-W674241) by Lactobacillus plantarum .
|
-
- HY-163548
-
|
|
Sialyltransferase
|
Cancer
|
|
SPP-002 is a sulfate analogue that acts as a potential Sialyltransferase (ST) inhibitor. SPP-002 selectively inhibits n-glycosialylation with inhibition at least an order of magnitude greater than that of unmodified parental cholic acid (LCA). SPP-002 reduces tumor cell migration and invasion by inhibiting the integrin /FAK/Paxillin signaling pathway. SPP-002 can be used in the study of tumor metastasis .
|
-
- HY-122704A
-
|
Aminoquinuride dihydrochloride
|
FGFR
HSV
Tau Protein
|
Infection
Neurological Disease
Inflammation/Immunology
|
|
Surfen dihydrochloride is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen dihydrochloride inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 μM. Surfen dihydrochloride inhibits HSV-1 viral infection. Surfen dihydrochloride inhibits neural differentiation, delays remyelination, and alleviates EAE .
|
-
- HY-122704
-
|
Aminoquinuride
|
FGFR
HSV
Tau Protein
|
Infection
Neurological Disease
Inflammation/Immunology
|
|
Surfen is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 μM. Surfen inhibits HSV-1 viral infection. Surfen inhibits neural differentiation, delays remyelination, and alleviates EAE .
|
-
- HY-100897
-
|
|
Thrombin
|
Cardiovascular Disease
|
|
Sulodexide is an orally active mixture of glycosaminoglycans composed of low molecular weight heparin (80%) and dermatan sulfate (20%). Sulodexide exhibits antithrombotic activity through interaction with antithrombin III (AT III) and heparin cofactor II (HC II), and inhibition of thrombin formation. Sulodexide exhibits profibrinolytic activity through release of tissue plasminogen activator (tPA). Sulodexide exhibits endothelial protective and anti-inflammatory effect, ameliorates chronic venous disease .
|
-
- HY-P99797
-
|
JR-141
|
Transferrin Receptor
|
Neurological Disease
|
|
Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .
|
-
- HY-119695AR
-
|
Tenivastatin ammonium (Standard)
|
Reference Standards
HMG-CoA Reductase (HMGCR)
Reactive Oxygen Species (ROS)
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Simvastatin acid (ammonium) (Standard) is the analytical standard of Simvastatin acid (ammonium). This product is intended for research and analytical applications. Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-108903A
-
|
|
Glycosidase
Biochemical Assay Reagents
|
Endocrinology
|
|
Hyaluronidase, Ovine testes is an endoglycosidase. Hyaluronidase, Ovine testes specifically degrades Hyaluronic acid (HY-B0633A) and Chondroitin sulfate (HY-B2162) by hydrolyzing β-glycosidic bonds in acidic mucopolysaccharides. Hyaluronidase, Ovine testes disperses follicular cells during fertilization by breaking down the hyaluronic acid-rich cumulus. Hyaluronidase, Ovine testes can be used in the study of fertility-related diseases .
|
-
- HY-B1268
-
|
Dioctyl sulfosuccinate sodium salt
|
HSV
|
Others
|
|
Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice .
|
-
- HY-P10552
-
|
|
CXCR
|
Inflammation/Immunology
|
|
pCXCL8-1aa is an anti-inflammatory peptide. pCXCL8-1aa competitively inhibits the binding of CXCL8 to glycosaminoglycans such as heparin sulfate (HS) by binding with high affinity. This reduces the presentation of CXCL8 on the surface of vascular endothelial cells, thereby inhibiting neutrophil migration and inflammatory responses. pCXCL8-1aa can be used to study inflammatory diseases such as rheumatoid arthritis .
|
-
- HY-119695S
-
-
- HY-W039883
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,3,4,6-Tetra-O-acetyl-2-amino-2-deoxy-α-D-glucopyranose sulfate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-119695AS
-
|
Tenivastatin-d6 ammonium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-119695AS1
-
-
- HY-112724A
-
|
SHR0302 sulfate
|
JAK
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Ivarmacitinib (SHR0302) sulfate is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of Ivarmacitinib for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. Ivarmacitinib inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. Ivarmacitinib has anti-proliferative and anti-inflammatory effects .
|
-
- HY-B1752
-
|
LY 171555; (-)-LY 141865
|
Dopamine Receptor
|
Neurological Disease
|
|
Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist with activity in reducing hypothalamic norepinephrine concentrations. The effects of Quinpirole are not produced by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity. By activating D2 receptors, Quinpirole leads to a decrease in dopamine metabolites, a decrease in hypothalamic norepinephrine concentrations, and a possible increase in MHPG sulfate by enhancing norepinephrine release .
|
-
- HY-Y1092R
-
|
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
N,N-Dicyclohexylcarbodiimide(DCC) (Standard) is the analytical standard of N,N-Dicyclohexylcarbodiimide(DCC). This product is intended for research and analytical applications. N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
-
- HY-133012
-
|
|
TRP Channel
|
Neurological Disease
|
|
GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model .
|
-
- HY-118984
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide (LPS, HY-D1056) with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-α induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis (namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model) .
|
-
- HY-149802
-
|
|
GLUT
|
Metabolic Disease
|
|
SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
|
-
- HY-149276
-
|
|
GLUT
|
Metabolic Disease
|
|
SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
|
-
- HY-103539
-
|
|
γ-secretase
|
Metabolic Disease
|
|
3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum .
|
-
- HY-120812
-
|
|
HIV Protease
|
Infection
|
|
HIV-IN-11 is part of the hydroxylaminoglutaramide (HAPA) transition state isomeric series of HIV protease inhibitors and is a potent and selective inhibitor of HIV-1 protease. HIV-IN-11 competitively inhibits HIV-1 PR (Ki: 0.049 nM) and potently inhibits replication of HIV(IIIb)-infected MT4 lymphocytes at concentrations of 25.0-50.0 nM. HIV-IN-11 displays a longer half-life than indinavir sulfate in animal models and serves as a promising second-generation HIV protease inhibitor .
|
-
- HY-P5982
-
|
|
Phosphatase
|
Neurological Disease
|
|
PTPσ Inhibitor, ISP can bind to recombinant human PTPs and inhibits PTPσ signaling. PTPσ Inhibitor, ISP can penetrate the membrane and relieves the chondroitin sulfate proteoglycan (CSPG)-mediated axonal sprouting inhibition in spinal cord injury model. PTPσ Inhibitor, ISP enhances remyelination in LPC-induced demyelinated spinal cord. PTPσ Inhibitor, ISP also promotes oligodendrocyte progenitor cells (OPCs) migration, maturation, remyelination, and functional recovery in animal models of Multiple Sclerosis (MS) .
|
-
- HY-B1268R
-
|
Dioctyl sulfosuccinate sodium salt (Standard)
|
Reference Standards
HSV
|
Others
|
|
Docusate (Sodium) (Standard) is the analytical standard of Docusate (Sodium). This product is intended for research and analytical applications. Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice .
|
-
- HY-N14924
-
|
|
Bacterial
|
Infection
|
|
Oganomycin GA is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria .
|
-
- HY-19891A
-
|
PG545 free acid
|
Toll-like Receptor (TLR)
SARS-CoV
|
Infection
Inflammation/Immunology
Cancer
|
|
Pixatimod free acid (PG545 free acid) is a mimetic of Heparan Sulfate (HY-101916), and exhibits inhibitory activity against heparanase. Pixatimod free acid binds to the S1 receptor binding domain (RBD) of the SARS-CoV-2 virus, that inhibits SARS-CoV-2 isolate strains with EC50 of 2.4-13.8 µg/mL. Pixatimod free acid is an agonist for TLR9 signaling pathway, enhances the activity of dendritic cells (DCs), activates natural killer cells, and exhibits immunomodulatory and anti-tumor activities .
|
-
- HY-107867S1
-
|
|
Isotope-Labeled Compounds
P2Y Receptor
|
Inflammation/Immunology
|
|
(Rac)-Clopidogrel hydrogen-d9 sulfate is the deuterium labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .
|
-
- HY-157161
-
|
|
11β-HSD
|
Cancer
|
|
11β-HSD2-IN-1 (compound CDSN) is a potent inhibitor of 11β-HSD2, inhibiting the metabolism of Cholestane-3β,5α,6β-triol (CT) in cells by 11β-HSD2 into the tumor promoter, carcinosterone. 11β-HSD2-IN-1 inhibits testosterone biosynthesis, thereby inhibiting MCF-7 cell proliferation. 11β-HSD2-IN-1 has immune activity and antiviral infection effects .
|
-
- HY-17412S1
-
-
- HY-115004
-
|
|
FAAH
|
Neurological Disease
|
|
MM-433593 is a potent and selective inhibitor of fatty acid amide hydrolase-1 (FAAH-1) that is orally administered to inhibit pain, inflammation, and related disorders. Pharmacokinetic studies of MM-433593 in macaques revealed a biphasic elimination profile with a rapid distribution phase and a slower elimination phase, with a systemic clearance of 8-11 mL/min/kg. MM-433593 exhibits moderate oral bioavailability (14-21%) and its metabolism primarily involves oxidation of the methyl group on the indole ring, resulting in a variety of sulfate, glucuronide, or glutathione-conjugated metabolites .
|
-
- HY-N14926
-
|
|
Bacterial
|
Infection
|
|
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .
|
-
- HY-107867S2
-
|
|
Isotope-Labeled Compounds
P2Y Receptor
|
Cardiovascular Disease
|
|
Clopidogrel- 13C,d3 sulfate is the deuterium and 13C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .
|
-
- HY-155199
-
|
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
|
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor (IC50: 15 nM). PDE1-IN-5 has anti- inflammatory activity, and inhibits expression of iNOS, TNF-α, IL-1α, IL-1β, and IL-6 induced by LPS. PDE1-IN-5 has anti-inflammatory bowel disease (IBD) effects in the dextran sodium sulfate (DSS)-Induced colitis mice model. PDE1-IN-5 can be used for research of IBD .
|
-
- HY-155998
-
|
|
NF-κB
|
Inflammation/Immunology
|
|
NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay .
|
-
- HY-112624K
-
|
Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
|
Apoptosis
Autophagy
|
Others
|
|
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-159179
-
|
|
Integrin
|
Inflammation/Immunology
|
|
α4 integrin receptor antagonist 3 (Compound 11) is an orally active α4integrin receptor antagonist. α4 integrin receptor antagonist 3 can inhibit the adhesion of K562 cells mediated by the interaction between α4β1/VCAM-1 and α4β7/MAdCAM-1, with IC50 values of 130 nM and 2 nM, respectively. α4 integrin receptor antagonist 3 has the potential to be used in the study of dextran sulfate sodium (DSS) colitis mouse model .
|
-
- HY-W250143
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.
|
-
- HY-N0648
-
|
|
Interleukin Related
Keap1-Nrf2
Heme Oxygenase (HO)
NF-κB
Apoptosis
|
Inflammation/Immunology
|
|
Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
|
-
- HY-N0648R
-
|
|
Reference Standards
Interleukin Related
Heme Oxygenase (HO)
Keap1-Nrf2
NF-κB
Apoptosis
|
Inflammation/Immunology
|
|
Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
|
-
- HY-W074143
-
|
|
Fluorescent Dye
|
Others
|
|
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe that can be used to modify the electrode surface to detect sulfate (S2O8 2-) and oxalate. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can generate excited state species based on electrochemical reactions and release photons through irreversible redox reactions. When used as a cathode to detect persulfate, it can avoid the interference of hydrogen evolution. At the same time, the anode shows a wide linear range for oxalate. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to construct a regenerable ECL sensor .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0430
-
|
Tracid Brilliant Red B
|
Dyes
|
|
Acid Red 249 (Tracid Brilliant Red B) is a kind of weak acid dye containing sulfate ion .
|
-
- HY-W110904
-
|
|
Dyes
|
|
Methylthymol blue tetrasodium is a metallochromic indicator dye and can be used for determination of sulfate and calcium .
|
-
- HY-113238F
-
|
FITC-Sulfolithocholic acid
|
Fluorescent Dyes/Probes
|
|
FITC-Lithocholic acid 3-sulfate (FITC-Sulfolithocholic acid) is a FITC-labeled Lithocholic acid 3-sulfate, which is a sulfated biliary metabolite. Lithocholic acid 3-sulfate selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate can be used for the research of pathogenesis of cholestatic liver diseases .
|
-
- HY-D1633
-
|
|
Fluorescent Dyes/Probes
|
|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase .
|
-
- HY-D1633A
-
|
|
Fluorescent Dyes/Probes
|
|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase .
|
-
- HY-D1213
-
|
Dipotassium nitrocatechol sulfate
|
Dyes
|
|
4-Nitrocatechol sulfate dipotassium salt (Dipotassium nitrocatechol sulfate) is a chromogenic substrate for sulphatase .
|
-
- HY-W009454
-
|
4-Nitopheyl Sulfate potassium
|
Dyes
|
|
p-Nitrophenyl Sulfate Potassium is a chromogenic substrate for arylsulfatase. p-Nitrophenyl Sulfate Potassium is released by arylsulfonase cleavage, and the activity of arylsulfonase can be quantitatively determined by colorimetric detection at 400 nm .
|
-
- HY-D0745
-
|
|
Dyes
|
|
Acid red 405 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-D0613
-
|
|
Dyes
|
|
Acid Red 337 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-D0398
-
|
|
Dyes
|
|
Acid red 42 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-D0660
-
|
|
Dyes
|
|
Acid red 131 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-D1209
-
|
|
Dyes
|
|
Acid Red 35 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
|
-
- HY-101900
-
|
Nile blue sulfate
|
Fluorescent Dyes/Probes
|
|
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
|
-
- HY-D0241
-
|
Variamine Blue RT sulfate
|
Dyes
|
|
4-Aminodiphenylamine sulfate (Variamine Blue RT sulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W250143
-
|
|
Dyes
|
|
Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.
|
-
- HY-W074143
-
|
|
Fluorescent Dyes/Probes
|
|
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe that can be used to modify the electrode surface to detect sulfate (S2O8 2-) and oxalate. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can generate excited state species based on electrochemical reactions and release photons through irreversible redox reactions. When used as a cathode to detect persulfate, it can avoid the interference of hydrogen evolution. At the same time, the anode shows a wide linear range for oxalate. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to construct a regenerable ECL sensor .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W145658
-
|
Heparamine sodium salt
|
Biochemical Assay Reagents
|
|
De-N-sulfated heparin (Heparin I-H) sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W094475C
-
|
Epsom salts, for cell culture
|
Buffer Reagents
|
|
Magnesium sulfate heptahydrate, for cell culture is a biochemical assay reagent and is suitable fo cell culture .
|
-
- HY-E70173
-
|
EC:2.8.2.-; HS6ST1
|
Enzyme Substrates
|
|
Heparan Sulfate 6-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 6-O-Sulfotransferase 1 is important in heparan sulfate biosynthesis .
|
-
- HY-W115721
-
|
Sodium rhodizonate dibasic
|
Indicators
|
|
Rhodizonic acid disodium (Sodium rhodizonate dibasic) can be used as an indicator in the volumetric determination of barium and sulfates. Rhodizonic acid disodium is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-E70175
-
|
EC:2.8.2.30; HS3ST3B1; 3OST3B1
|
Enzyme Substrates
|
|
Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is a sulfotransferase. Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is important in heparan sulfate biosynthesis .
|
-
- HY-E70170
-
|
EC:2.8.2.-; HS2ST1
|
Enzyme Substrates
|
|
Heparan Sulfate 2-O-Sulfotransferase 1 is a sulfotransferase and influences dermatan sulfate biosynthesis .
|
-
- HY-W094477D
-
|
Epsom salts, for molecular biology
|
Buffer Reagents
|
|
Magnesium sulfate heptahydrate, for molecular biology is a biochemical assay reagent and is suitable fo molecular biology.
|
-
- HY-E70174
-
|
EC:2.8.2.-; HS6ST3
|
Enzyme Substrates
|
|
Heparan Sulfate 6-O-Sulfotransferase 3 is a sulfotransferase. Heparan Sulfate 6-O-Sulfotransferase 3 is important in heparan sulfate biosynthesis .
|
-
- HY-E70171
-
|
EC:2.8.2.23; HS3ST1
|
Enzyme Substrates
|
|
Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure .
|
-
- HY-W094475E
-
|
Epsom salts (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
|
-
- HY-E70176
-
|
EC:2.8.2.8; NDST1
|
Enzyme Substrates
|
|
N-Deacetylase/N-Sulfotransferase 1 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 1 modifies heparan sulfate-dependent growth factor and morphogen signalling .
|
-
- HY-116282P
-
|
|
Cell Assay Reagents
|
|
Dextran sulfate, high sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, high sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-116282J
-
|
|
Cell Assay Reagents
|
|
Dextran sulfate, low sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-116282M
-
|
|
Cell Assay Reagents
|
|
Dextran sulfate, low sulfate (MW 40000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 40000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-W009439
-
|
GlcN6P; D-Glucosamine-6-sulfate
|
Cell Assay Reagents
|
|
Glucosamine 6-sulfate (GlcN6P) is an organic cofactor that splits phosphodiester bonds. Glucosamine 6-sulfate plays a variety of catalytic roles in glmS ribozymes .
|
-
- HY-W776843
-
|
|
Carbohydrates
|
|
Glycochenodeoxycholic acid 3-sulfate (disodium) is a biochemical assay reagent.
|
-
- HY-NP183
-
|
HSPG
|
Native Proteins
|
|
Heparan sulfate proteoglycan (HSPG) is a glycoprotein composed of a core protein covalently bound to heparin sulfate chains. Heparan sulfate proteoglycan is an integral part of the basement membrane .
|
-
- HY-E70177
-
|
EC:2.8.2.8; NDST2; N-HSST 2
|
Enzyme Substrates
|
|
N-Deacetylase/N-Sulfotransferase 2 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 2 synthesizes serglycin-bound heparin chains in mast cells .
|
-
- HY-E70186
-
|
EC:3.1.6.12; ARSB
|
Enzyme Substrates
|
|
Arylsulfatase B (EC:3.1.6.12, ARSB) removes a chemical group known as a sulfate from two GAGs called dermatan sulfate and chondroitin sulfate .
|
-
- HY-157359
-
|
|
Microbial Culture
|
|
Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
|
-
- HY-W096997A
-
|
Sodium capryl sulfate, 95%
|
Surfactants
|
|
Sodium octyl sulfate (SOS), 95% (Sodium capryl sulfate, 95%) is an anionic detergent and ion-pairing agent.
|
-
- HY-W115752
-
|
Diamine sulfate (99%)
|
Cell Assay Reagents
|
|
Hydrazine sulfate (99%) (Diamine sulfate (99%)) is used as an insecticide, sterilant, and plant growth inhibitor in agriculture. Hydrazine sulfate (99%) is a biomaterial or organic compound that can be used in life science research .
|
-
- HY-116282
-
|
DSS (MW 5000); DXS (MW 5000)
|
Carbohydrates
|
|
Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
|
-
- HY-116282I
-
|
DSS (MW>500000); DXS (MW>500000)
|
Cell Assay Reagents
|
|
Dextran sulfate sodium salt (MW>500000) (DSS (MW>500000)) is a negatively charged sulfated polysaccharide. Dextran sulfate sodium salt has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate sodium salt can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .
|
-
- HY-Y1267D
-
|
|
Buffer Reagents
|
|
Magnesium sulfate, for cell culture is a bioreagent. Magnesium sulfate is a calcium antagonist and a potent L-type calcium channel inhibitor, as well as a tocolytic. Magnesium sulfate has anti-inflammatory, anticonvulsant, vasodilatory, and neuroprotective effects. Magnesium sulfate can be used in the research of diseases such as preeclampsia/eclampsia .
|
-
- HY-Y1369C
-
|
Manganous sulfate monohydrate, for cell culture
|
Cell Assay Reagents
|
|
Manganese sulfate monohydrate, for cell culture (Manganous sulfate monohydrate, for cell culture) can be used to prepare micronutrients. Manganese sulfate monohydrate, for cell culture is a biomaterial or organic compound that can be used as a life science research-related material .
|
-
- HY-113238A
-
|
Sulfolithocholic acid disodium; LCAS disodium
|
Cell Assay Reagents
|
|
Lithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 41 and 42.4 (absence of Zn 2+) and 0.88 and 0.97 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Lithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Lithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-137255
-
|
3-Sulfotaurolithocholic acid disodium
|
Surfactants
|
|
Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 71.6 and 69.4 (absence of Zn 2+) and 9 and 9.6 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease .
|
-
- HY-Y1103
-
|
Ferrous sulfate heptahydrate, 99%
|
Buffer Reagents
|
|
Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .
|
-
- HY-172163
-
|
|
Cell Assay Reagents
|
|
FITC-dextran sulfate, 4kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 4 kDa .
|
-
- HY-172163C
-
|
|
Cell Assay Reagents
|
|
FITC-dextran sulfate, 500kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 500 kDa .
|
-
- HY-172163A
-
|
|
Cell Assay Reagents
|
|
FITC-dextran sulfate, 10kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 10 kDa .
|
-
- HY-172163B
-
|
|
Cell Assay Reagents
|
|
FITC-dextran sulfate, 40kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 40 kDa .
|
-
- HY-W145483
-
|
N-Acetyl-de-O-sulfated heparin (Heparin IV-A) (sodium)
|
Enzyme Substrates
|
|
Heparin IV-A sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y0316BR
-
|
Sodium lauryl sulfate for electrophoresis (Standard); Laurylsulfuric acid sodium salt for electrophoresis (Standard)
|
Surfactants
|
|
Sodium dodecyl sulfate for electrophoresis (Standard) is the analytical standard of Sodium dodecyl sulfate for electrophoresis. This product is intended for research and analytical applications. Sodium dodecyl sulfate for electrophoresis is a high purity sodium dodecyl sulfate (SDS) with a minimum purity of 98.5%. It is an anionic detergent commonly used in electrophoretic procedures to denature and impart a negative charge to proteins, allowing separation based on size and charge. Sodium dodecyl sulfate for electrophoresis has unique chemical properties that make it an effective ingredient in many laboratory applications, helping to improve the resolution and sensitivity of protein analysis.
|
-
- HY-P3025
-
|
|
Native Proteins
|
|
Salmine sulfate is an antimicrobial protein. Salmine sulfate is a polycationic coacervate embolic agent that can be used in tumor research .
|
-
- HY-W051140
-
|
Disilver sulfate, 99%
|
Indicators
|
|
Silver sulfate, 99% (Disilver sulfate, 99%) can be used for colorimetric determination of nitrates, phosphates, and fluoride, or for the determination of chromium and cobalt in water. Silver sulfate, 99% is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-Y1878C
-
|
Cupric sulfate anhydrous, 99%
|
Buffer Reagents
|
|
Anhydrous copper sulfate, 99% (Cupric sulfate anhydrous, 99%) is an orally administerable disinfectant. Anhydrous copper sulfate, 99% can be used as a biomaterial or organic compound related to life sciences research, and it can increase the Cu content in rat organs .
|
-
- HY-W276164
-
|
Sodium stearyl sulfate
|
Biochemical Assay Reagents
|
|
Sodium octadecyl sulfate (Sodium stearyl sulfate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-Y1103A
-
|
Ferrous sulfate heptahydrate, for cell culture, 99%
|
Buffer Reagents
|
|
Iron(II) sulfate heptahydrate, for cell culture, 99% (Ferrous sulfate heptahydrate, for cell culture, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, for cell culture, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, for cell culture, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, for cell culture, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .
|
-
- HY-Y1881A
-
|
|
Buffer Reagents
|
|
Copper sulfate pentahydrate, 99% is a biochemical reagent. Copper sulfate pentahydrate, 99% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, 99% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, 99% is cytotoxic to various cells. Copper sulfate pentahydrate, 99% has antioxidant activity. Copper sulfate pentahydrate, 99% can be used in the research of diabetes, Parkinson's disease and DMBA (HY-W011845)-induced tumors .
|
-
- HY-W019950
-
|
Chromic potassium sulfate (98%); Chrome alum (98%)
|
Cell Assay Reagents
|
|
Chromium(Ⅲ) potassium sulfate dodecahydrate (98%) (Chromic potassium sulfate (98%); Chrome alum (98%)), can be used as a fixative for microscopic analysis. Chromium(Ⅲ) potassium sulfate dodecahydrate (98%) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-Y1267
-
|
|
Biochemical Assay Reagents
|
|
Magnesium sulfate is a calcium antagonist and a potent L-type calcium channel inhibitor, as well as a tocolytic. Magnesium sulfate has anti-inflammatory, anticonvulsant, vasodilatory, and neuroprotective effects. Magnesium sulfate can be used in the research of diseases such as preeclampsia/eclampsia .
|
-
- HY-116282W
-
|
DSS (MW 6500-10000); DXS (MW 6500-10000)
|
Cell Assay Reagents
|
|
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .
|
-
- HY-E70172
-
|
EC:2.8.2.23; HS3ST4; 3-OST-4
|
Enzyme Substrates
|
|
Heparan Sulfate 3-O-Sulfotransferase 4 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase 4 regulates Notch signaling .
|
-
- HY-167815
-
|
|
Cell Assay Reagents
|
|
Myo-Inositol hexasulfate hexapotassium is a sulfated derivative of inositol that has the activity of mimicking highly sulfated polysaccharides such as heparin, affecting many cell signaling pathways.
|
-
- HY-B0560B
-
|
Baryta white
|
Biochemical Assay Reagents
|
|
Barium sulfate (Baryta white) can be used as an opacifier. Barium sulfate is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-137855
-
|
|
Enzyme Substrates
|
|
4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.
|
-
- HY-116282H
-
|
DSS (MW 9000-20000); DXS (MW 9000-20000)
|
Cell Assay Reagents
|
|
Dextran sulfate sodium salt (DSS) (MW 9000-20000) is a polymer of dehydrated glucose with a molecular weight of approximately 9000-20000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 9000-20000) is a biocompatible and biodegradable biochemical reagent and can be used for pharmaceutical and biomedical applications .
|
-
- HY-W009425R
-
|
|
Biochemical Assay Reagents
|
|
N,N-Diethyl-p-phenylenediamine Sulfate (Standard) is the analytical standard of N,N-Diethyl-p-phenylenediamine Sulfate. This product is intended for research and analytical applications. N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-W094709
-
- HY-W099535
-
|
|
Biochemical Assay Reagents
|
|
Lithium dodecyl sulfate is an anionic detergent and surfactant that can be used in place of SDS for electrophoresis under low temperatures. Lithium dodecyl sulfate can be used for synthesis of nanomaterials and chromatography .
|
- HY-Y0317E
-
|
Disodium sulfate (Pharmaceutical primary standard, USP)
|
Buffer Reagents
|
|
Sodium sulfate anhydrous (Disodium sulfate), can be widely used as a desiccant, pH regulator, etc. in biochemical experiments. It is a reference standard grade of the United States Pharmacopeia (USP), pharmaceutical primary standard.
|
- HY-W094350
-
|
Gypsum fibrosum (99%)
|
Thickeners
|
|
Calcium sulfate dihydrate (99%) (Gypsum fibrosum (99%)) is a desiccant. Calcium sulfate dihydrate (99%) is a kind of biological materials or organic compounds that are widely used in life science research .
|
- HY-Y1881B
-
|
|
Buffer Reagents
|
|
Copper sulfate pentahydrate, for cell culture, 98% is a biochemical reagent. Copper sulfate pentahydrate, for cell culture, 98% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, for cell culture, 98% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, for cell culture, 98% is cytotoxic to various cells .
|
- HY-W284558
-
- HY-Y0317IR
-
|
Disodium sulfate, meets analytical specification of Ph. Eur. BP USP (Standard)
|
Buffer Reagents
|
|
Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP (Standard) is the analytical standard of Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP. This product is intended for research and analytical applications. Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
|
- HY-158221
-
|
CSMA
|
3D Bioprinting
|
Chondroitin Sulfate Methacryloyl (CSMA) is methacrylated chondroitin sulfate and is biocompatible. Chondroitin Sulfate Methacryloyl has a higher degree of methacrylation than HAMA (HY-158220), and the degree of methacrylation is closely related to customizable mechanical properties, swelling properties and enzymatic degradability. Chondroitin Sulfate Methacryloyl is a versatile biomaterial suitable for biomimetic hydrogel scaffolds and an ideal 3D printing hydrogel ink . Chondroitin Sulfate Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.
|
- HY-W106012
-
|
|
Chelators
|
|
Aluminum sulfate hexadecahydrate is a kind of biochemical reagent.
|
- HY-W706303
-
|
|
Carbohydrates
|
|
Diethanolamine dodecyl sulfate is a biochemical assay reagent.
|
- HY-W019901B
-
|
Gypsum ustum (97%)
|
Thickeners
|
|
Anhydrous calcium sulfate (97%) (Gypsum ustum (97%)) can be used in medical materials. Anhydrous calcium sulfate (97%) is a kind of biological materials or organic compounds that are widely used in life science research .
|
- HY-Y0316B
-
|
Sodium lauryl sulfate for electrophoresis; Laurylsulfuric acid sodium salt for electrophoresis
|
Surfactants
|
|
Sodium dodecyl sulfate for electrophoresis is a high purity sodium dodecyl sulfate (SDS) with a minimum purity of 98.5%. It is an anionic detergent commonly used in electrophoretic procedures to denature and impart a negative charge to proteins, allowing separation based on size and charge. Sodium dodecyl sulfate for electrophoresis has unique chemical properties that make it an effective ingredient in many laboratory applications, helping to improve the resolution and sensitivity of protein analysis.
|
- HY-W019927
-
|
Ammonium ferric sulfate dodecahydrate, 99%
|
Indicators
|
|
Ammonium iron(Ⅲ) sulfate dodecahydrate, 99% is a biochemical reagent. Ammonium iron(Ⅲ) sulfate dodecahydrate, 99% is often used as a source material for the reagent solution or the standard solution of iron(III) .
|
- HY-W094475D
-
|
Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC
|
Buffer Reagents
|
|
Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC is currently the anticonvulsant of choice for the prevention and control of eclamptic fits. Magnesium sulfate is also widely used as a tocolytic agent .
|
- HY-W501565
-
|
SUS
|
Surfactants
|
|
Sodium 1-undecyl sulfate (SUS) is a kind of biochemical reagent.
|
- HY-W328317
-
|
Azoic diazo No. 4, 90%
|
Indicators
|
|
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.
|
- HY-Y1083H
-
|
Salt of lemery, 99%
|
Buffer Reagents
|
|
Potassium sulfate, 99% (Salt of lemery, 99%) can be used in biochemical tests for serum proteins, the determination of blood potassium and other potassium salts, and the preparation of protein capillary electrophoresis buffers. Potassium sulfate, 99% is a kind of biological materials or organic compounds that are widely used in life science research .
|
- HY-Y0945B
-
|
|
Cell Assay Reagents
|
|
Iron (III) sulfate hydrate,for plant cell culture is a biochemical assay reagent.
|
- HY-Y1083C
-
|
Salt of lemery, for cell culture
|
Buffer Reagents
|
|
Potassium sulfate, for cell culture (Salt of lemery, for cell culture) can be used in biochemical tests for serum proteins, the determination of blood potassium and other potassium salts, and the preparation of protein capillary electrophoresis buffers. Potassium sulfate, for cell culture is a kind of biological materials or organic compounds that are widely used in life science research .
|
- HY-157348
-
|
LST
|
Microbial Culture
|
|
Lauryl Sulfate Tryptose Broth can be used for preparation of selective enrichment broth .
|
- HY-W019976
-
|
|
Enzyme Substrates
|
|
Cadmium sulfate hydrate,99.995% trace metals basis is a kind of biochemical reagent.
|
- HY-W019832
-
|
|
Carbohydrates
|
|
Glucosamine 3-sulfate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
- HY-Y0317H
-
|
Disodium sulfate, for cell culture
|
Buffer Reagents
|
|
Sodium sulfate anhydrous, for cell culture is a drying agent in organic synthesis, which can be used for cell culture .
|
- HY-W127367
-
|
|
Drug Delivery
|
|
Sodium eicosyl sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W096994A
-
|
Tetramethylammonium sulphate
|
Biochemical Assay Reagents
|
|
Tetramethylammonium sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-137513
-
|
|
Carbohydrates
|
|
N-Acetyl-D-glucosamine 6-sulfate (sodium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
|
- HY-W127623
-
|
|
Biochemical Assay Reagents
|
|
Tris Dodecyl Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-137847
-
|
|
Enzyme Substrates
|
|
5-Bromo-4-chloro-3-indolyl sulfate (potassium) is a biochemical assay reagent.
|
- HY-B2162D
-
|
Chondroitin polysulfate sulfate (from chicken)
|
Carbohydrates
|
|
Chondroitin sulfate from Chicken is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W927849
-
|
Magnesium lauryl sulfate
|
Surfactants
|
|
Magnesium dodecyl sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-B2162C
-
|
Chondroitin polysulfate sulfate (from pig)
|
Carbohydrates
|
|
Chondroitin sulfate from Pig is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-B2162B
-
|
Chondroitin polysulfate sulfate sodium (from bovine)
|
Carbohydrates
|
|
Chondroitin sulfate from Bovine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-B2162E
-
|
Chondroitin polysulfate (from shark cartilage)
|
Carbohydrates
|
|
Chondroitin sulfate (from shark cartilage) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W130648
-
|
|
Biochemical Assay Reagents
|
|
Sodium 2-ethylhexyl sulfate (40% in water) is an anionic surfactant commonly used as a detergent, wetting agent, and emulsifier in various industrial processes, especially in the production of personal care products, cleaning agents, and textile auxiliaries. Sodium 2-ethylhexyl sulfate (40% in water) has unique chemical properties that make it an effective ingredient in many applications, helping to reduce surface tension and enhance cleaning power.
|
- HY-Y0317I
-
|
Disodium sulfate, meets analytical specification of Ph. Eur. BP USP
|
Buffer Reagents
|
|
Sodium sulfate anhydrous, meets analytical specification of Ph. Eur. BP USP, an inorganic salt, is a biochemical reagent that can be used for life science related research.
|
- HY-B0560A
-
|
|
Cell Assay Reagents
|
|
Ammonium aluminum sulfate dodecahydrate is a biomolecule precipitation agent that can change the solubility of proteins by interacting with water molecules, thereby effectively purifying proteins.
|
- HY-W739789
-
|
|
Biochemical Assay Reagents
|
|
(6R)-Tetrahydro-L-biopterin (sulfate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W145672
-
|
|
Carbohydrates
|
|
D-Galactose-4-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W009425
-
|
|
Biochemical Assay Reagents
|
|
N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-W145673
-
|
D-Galactose-6-O-sulphate sodium salt
|
Carbohydrates
|
|
D-Galactose-6-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-W698571
-
|
4-O-(3-O-Sulfo-β-D-galactopyranosyl)-D-glucose
|
Carbohydrates
|
|
Lactose-3'-sulfate (4-O-(3-O-Sulfo-β-D-galactopyranosyl)-D-glucose) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
- HY-157357
-
|
|
Microbial Culture
|
|
Fungi Agar Medium can be used in sterile growth tests. Fungi Agar Medium ingredients include peptone, glucose, yeast powder, potassium dihydrogen phosphate, magnesium sulfate, and agar.
|
- HY-W145694
-
|
|
Biochemical Assay Reagents
|
|
N-Acetyl-D-galactosamine-4-O-sulfate sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-157370
-
|
|
Microbial Culture
|
|
Blood Enrichment Medium can be used for enrichment culture of pathogenic bacteria in blood. Blood Enrichment Medium ingredients include peptone, beef extract powder, NaCl, glucose, sodium citrate, para-aminobenzoic acid, magnesium sulfate, phenol red .
|
- HY-P3160
-
|
|
Native Proteins
|
|
Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
|
- HY-157367
-
|
|
Microbial Culture
|
|
Bismuth Sulfite Agar Medium can be used for selective isolation and culture of Salmonella. Bismuth Sulfite Agar Medium ingredients include tryptone, peptone, beef powder, ferrous sulfate, bismuth sulfite, disodium hydrogen phosphate, glucose, brilliant green, agar .
|
- HY-B2241A
-
|
Aluminum potassium sulfate dodecahydrate, for cell culture
|
Cell Assay Reagents
|
|
Potassiumalum, for cell culture (Aluminum potassium sulfate dodecahydrate, for cell culture) is an egg white adjuvant that can induce allergic reactions in mice; it can also be used for bacterial staining. Potassiumalum, for cell culture is a biomaterial or organic compound that can be used in life science research .
|
- HY-E70190
-
|
EC:2.8.2.20; TPST2
|
Enzyme Substrates
|
|
Tyrosylprotein Sulfotransferase 2 (TPST-2) is a subtype of TPST. Tyrosylprotein Sulfotransferase is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation of soluble and membrane proteins passing through this compartment .
|
- HY-172486
-
|
|
Drug Delivery
|
|
DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172484
-
|
|
Drug Delivery
|
|
DSPE-PEG1000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG1000-LTLRWVGLMS can be used for drug delivery .
|
- HY-172485A
-
|
|
Drug Delivery
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
- HY-172485
-
|
|
Drug Delivery
|
|
DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery .
|
- HY-W008992
-
|
8-Hydroxyquinoline sulfate hydrate
|
Biochemical Assay Reagents
|
|
Quinolin-8-ol sulfate hydrate is an organic compound commonly used in dyes and as a raw material for chemical analysis. It can cooperate with metal ions to form dyes, and is widely used in the fields of dyes, printing and textile manufacturing. In addition, the compound also has good toxicity and biocompatibility, and is also used in some medical fields.
|
- HY-Y1092
-
|
|
Biochemical Assay Reagents
|
|
N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
- HY-W099641
-
|
|
Biochemical Assay Reagents
|
|
Methyltrioctylammonium hydrogen sulfate is a quaternary ammonium salt that is mainly used as an extraction solvent and a phase transfer catalyst in various chemical reactions. It is also used as an electrolyte in electrochemical devices such as batteries and fuel cells, and as a building block for the synthesis of pharmaceuticals and agrochemicals. MTOAHS are multifunctional compounds with many potential industrial applications due to their reactivity, stability, and ability to selectively extract certain compounds from mixtures.
|
- HY-W039883
-
|
|
Carbohydrates
|
|
1,3,4,6-Tetra-O-acetyl-2-amino-2-deoxy-α-D-glucopyranose sulfate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
- HY-Y1092R
-
|
|
Biochemical Assay Reagents
|
|
N,N-Dicyclohexylcarbodiimide(DCC) (Standard) is the analytical standard of N,N-Dicyclohexylcarbodiimide(DCC). This product is intended for research and analytical applications. N,N-Dicyclohexylcarbodiimide(DCC) is a dehydrating and condensing agent. N,N-Dicyclohexylcarbodiimide(DCC) enhances adenylate cyclase activity. N,N-Dicyclohexylcarbodiimide(DCC) inhibits amine accumulation. N,N-Dicyclohexylcarbodiimide(DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides .
|
- HY-112624K
-
|
Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
|
Thickeners
|
|
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5055
-
|
|
Peptides
|
Others
|
|
Gastrin I (human) (sulfated) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P2678
-
|
|
Cholecystokinin Receptor
|
Metabolic Disease
|
|
CCK (26-31) (non-sulfated) is the N-terminal fragment of CCK, a peptide hormone found in the gut and brain that stimulates digestion, regulates satiety, and is associated with anxiety. CCK (26-31) is also less active in non-sulfated than in sulfated form .
|
-
- HY-P4325
-
|
|
Thrombin
|
Others
|
|
Hirudin (55-65) (sulfated) is a fragment of Hirudin with anticoagulant effects. Hirudin is a thrombin inhibitor with blood anticoagulant property.
|
-
- HY-P2677
-
|
|
Cholecystokinin Receptor
|
Metabolic Disease
|
|
CCK (26-31) (sulfated) is the N-terminal fragment of CCK, a peptide hormone found in the gut and brain that stimulates digestion, regulates satiety, and is associated with anxiety .
|
-
- HY-P4795
-
|
|
Thrombin
|
Others
|
|
Acetyl-Hirudin (55-65) (sulfated) is a Acetyl-fragment of Hirudin. Hirudin is a thrombin inhibitor with blood anticoagulant property .
|
-
- HY-P2490
-
|
|
Thrombin
|
Metabolic Disease
|
|
Acetyl-Hirudin (54-65) (sulfated) is a acetyl-fragment of Hirudin which binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex .
|
-
- HY-P4721
-
|
|
Thrombin
|
Cardiovascular Disease
|
|
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an antithrombotic agent. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 μM .
|
-
- HY-P2165
-
-
- HY-P5519
-
|
|
Peptides
|
Others
|
|
[Thr28, Nle31]-Cholecystokinin (25-33) is a biological active peptide. (Cholecystokinin (CCK) acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.This Cholecystokinin (CCK) analog retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements (Thr 28 and Nle31 were substituted for Methionine). The predominant conformation contains a gamma-turn centered on Thr4, separated by Gly5 from a helical segment that comprises the C-terminal residues.)
|
-
- HY-A0248R
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Polymyxin B (Sulfate) (Standard) is the analytical standard of Polymyxin B (Sulfate). This product is intended for research and analytical applications. Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo .
|
-
- HY-A0248
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo .
|
-
- HY-P0263R
-
|
|
Reference Standards
Bacterial
Fungal
Antibiotic
|
Infection
|
|
Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
|
-
- HY-113084
-
|
|
iGluR
Endogenous Metabolite
|
Neurological Disease
|
|
L-Cysteine S-sulfate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptor agonist. L-Cysteine S-sulfate is the substrate for cystine lyase, and can be used in mass spectrometry operations .
|
-
- HY-107027
-
|
|
Antibiotic
|
Infection
|
|
Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa .
|
-
- HY-77026
-
-
- HY-P2123A
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria .
|
-
- HY-P11101
-
|
|
Biochemical Assay Reagents
|
Others
|
|
plCSA-BP is a Placental CSA-binding peptide. plCSA-BP binds specifically to trophoblasts and not to other cell types in the placenta or to CSA-expressing cells in other tissues. plCSA-BP can guide nanoparticles for the targeted delivery of payloads (such as Indocyanine green (ICG) (HY-D0711) and Methotrexate (MTX) (HY-14519)) to the placenta, promising for placenta-specific drug delivery .
|
-
- HY-P10552
-
|
|
CXCR
|
Inflammation/Immunology
|
|
pCXCL8-1aa is an anti-inflammatory peptide. pCXCL8-1aa competitively inhibits the binding of CXCL8 to glycosaminoglycans such as heparin sulfate (HS) by binding with high affinity. This reduces the presentation of CXCL8 on the surface of vascular endothelial cells, thereby inhibiting neutrophil migration and inflammatory responses. pCXCL8-1aa can be used to study inflammatory diseases such as rheumatoid arthritis .
|
-
- HY-P5982
-
|
|
Phosphatase
|
Neurological Disease
|
|
PTPσ Inhibitor, ISP can bind to recombinant human PTPs and inhibits PTPσ signaling. PTPσ Inhibitor, ISP can penetrate the membrane and relieves the chondroitin sulfate proteoglycan (CSPG)-mediated axonal sprouting inhibition in spinal cord injury model. PTPσ Inhibitor, ISP enhances remyelination in LPC-induced demyelinated spinal cord. PTPσ Inhibitor, ISP also promotes oligodendrocyte progenitor cells (OPCs) migration, maturation, remyelination, and functional recovery in animal models of Multiple Sclerosis (MS) .
|
-
- HY-K1055
-
|
|
|
Kanamycin sulfate is an aminoglycoside antibiotic purified from Streptomyces kanamyceticus. It acts by binding to the 30S subunit of the bacterial ribosome and inhibiting protein synthesis in susceptible bacteria.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99797
-
|
JR-141
|
Transferrin Receptor
|
Neurological Disease
|
|
Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .
|
-
- HY-P99694
-
|
JR-171
|
Transferrin Receptor
|
Neurological Disease
|
|
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-122009
-
-
-
- HY-113074
-
-
-
- HY-W779068
-
-
-
- HY-N8460A
-
-
-
- HY-N7699
-
-
-
- HY-113360
-
-
-
- HY-N2028A
-
-
-
- HY-N8460
-
-
-
- HY-129071R
-
-
-
- HY-N0716BR
-
-
-
- HY-101406R
-
-
-
- HY-W740171
-
-
-
- HY-111431AR
-
|
|
Structural Classification
Natural Products
Human Gut Microbiota Metabolites
Source classification
Endogenous metabolite
|
JNK
p38 MAPK
Reactive Oxygen Species (ROS)
|
|
p-Cresyl sulfate (potassium) (Standard) is the analytical standard of p-Cresyl sulfate (potassium). This product is intended for research and analytical applications. p-Cresyl sulfate (p-Tolyl sulfate) potassium is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate potassium shows antiproliferation activity. p-Cresyl sulfate potassium increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate potassium induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways .
|
-
-
- HY-N0471AR
-
-
-
- HY-B0472R
-
-
-
- HY-W129471R
-
-
-
- HY-128442R
-
-
-
- HY-A0248R
-
-
-
- HY-111769
-
-
-
- HY-N0716B
-
-
-
- HY-13780R
-
-
-
- HY-113416R
-
|
DHEA sulfate (Standard); Prasterone sulfate (Standard)
|
Human Gut Microbiota Metabolites
Microorganisms
Source classification
Disease markers
Endocrine diseases
Nervous System Disorder
Endogenous metabolite
|
Reference Standards
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
-
- HY-B1581AR
-
-
-
- HY-B1222R
-
-
-
- HY-129071
-
-
-
- HY-B0765R
-
|
DHEA sulfate sodium (Standard); Prasterone sulfate sodium (Standard)
|
Structural Classification
Source classification
Endogenous metabolite
Steroids
|
Reference Standards
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt (Standard) is the analytical standard of Dehydroepiandrosterone sulfate sodium salt (HY-B0765). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
-
- HY-111355
-
-
-
- HY-113415A
-
-
-
- HY-111431
-
-
-
- HY-B0441AR
-
-
-
- HY-108826
-
-
-
- HY-N0487R
-
-
-
- HY-W017158R
-
-
-
- HY-B1304
-
-
-
- HY-113293BR
-
-
-
- HY-N6901
-
-
-
- HY-A0248
-
-
-
- HY-B0470R
-
-
-
- HY-N0471A
-
-
-
- HY-111431A
-
-
-
- HY-17565
-
-
-
- HY-45609R
-
-
-
- HY-B1751D
-
-
-
- HY-N0677AR
-
|
Potassium dehydroandrographolide succinate (Standard)
|
Structural Classification
Andrographis paniculata (Burm. F.) Nees
Acanthaceae
Terpenoids
Source classification
Diterpenoids
Plants
|
Antibiotic
Reference Standards
|
|
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .
|
-
-
- HY-N0113A
-
|
Ordenina sulfate; Peyocactine sulfate
|
Structural Classification
Monophenols
Gramineae
Source classification
Hordeum vulgare
Phenols
Plants
|
Antibiotic
|
|
Hordenine sulfate (Ordenina sulfate) is an active compound extracted from malted barley that has melanin-inhibiting activity. Hordenine sulfate significantly reduced melanin content and reduced intracellular cAMP levels. Hordenine sulfate inhibits the expression of proteins related to melanogenesis, including microblind transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2. Therefore, Hordenine sulfate can be used as an active ingredient to inhibit pigmentation .
|
-
-
- HY-B0394R
-
|
Tropine tropate sulfate monohydrate (Standard); DL-Hyoscyamine sulfate monohydrate (Standard)
|
Alkaloids
Structural Classification
Other Alkaloids
Source classification
Atropa belladonna Linn.
Solanaceae
Plants
|
Reference Standards
mAChR
|
|
Atropine (sulfate monohydrate) (Standard) is the analytical standard of Atropine (sulfate monohydrate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia .
|
-
-
- HY-17367AR
-
-
-
- HY-B1205AR
-
|
Tropine tropate sulfate (Standard); DL-Hyoscyamine sulfate (Standard); Sulfatropinol (Standard)
|
Alkaloids
Structural Classification
Other Alkaloids
Source classification
Atropa belladonna Linn.
Solanaceae
Plants
|
Reference Standards
mAChR
|
|
Atropine (sulfate) (Standard) is the analytical standard of Atropine (sulfate). This product is intended for research and analytical applications. Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia .
|
-
-
- HY-B0956R
-
-
-
- HY-A0276R
-
-
- HY-A0089R
-
-
- HY-128442
-
-
- HY-150526
-
-
- HY-N0488R
-
-
- HY-128420
-
-
- HY-B1222
-
-
- HY-101238R
-
-
- HY-B0765
-
|
DHEA sulfate sodium; Prasterone sulfate sodium
|
Structural Classification
Classification of Application Fields
Source classification
Metabolic Disease
Endogenous metabolite
Disease Research Fields
Steroids
|
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-113416
-
|
DHEA sulfate; Prasterone sulfate
|
Human Gut Microbiota Metabolites
Microorganisms
Source classification
Disease markers
Endocrine diseases
Nervous System Disorder
Endogenous metabolite
|
GABA Receptor
Sigma Receptor
iGluR
PPAR
NF-κB
|
|
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-101916
-
-
- HY-109051C
-
-
- HY-13780
-
-
- HY-N0252B
-
-
- HY-N0487
-
-
- HY-P0263R
-
|
|
Structural Classification
Natural Products
Animals
Source classification
|
Reference Standards
Bacterial
Fungal
Antibiotic
|
|
Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
|
-
- HY-W010668R
-
|
|
Source classification
Plants
|
Flavivirus
Dengue Virus
Reference Standards
Parasite
Potassium Channel
|
|
Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .
|
-
- HY-16566AR
-
-
- HY-17367A
-
-
- HY-W674241A
-
-
- HY-108307
-
-
- HY-B0441A
-
-
- HY-B0470
-
-
- HY-101406
-
-
- HY-B0956
-
-
- HY-111355B
-
|
|
Structural Classification
Classification of Application Fields
Source classification
Metabolic Disease
Endogenous metabolite
Disease Research Fields
Steroids
|
Endogenous Metabolite
|
|
Cholesteryl sulfate sodium is an orally available, NPC2-targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis (EC50=50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation .
|
-
- HY-17566
-
-
- HY-45609
-
-
- HY-B2162
-
-
- HY-W010973
-
-
- HY-B1581A
-
-
- HY-B0472
-
-
- HY-100787
-
-
- HY-113084
-
-
- HY-B0089A
-
-
- HY-113293B
-
-
- HY-113293A
-
-
- HY-B1228
-
-
- HY-131150
-
-
- HY-A0276
-
-
- HY-B1329
-
-
- HY-115762
-
-
- HY-B2162A
-
-
- HY-W011910
-
-
- HY-W792683
-
-
- HY-N3513
-
-
- HY-113152
-
-
- HY-W775100
-
-
- HY-N1523
-
-
- HY-B1304A
-
-
- HY-B1329R
-
-
- HY-W010668
-
|
|
Source classification
Plants
|
Flavivirus
Dengue Virus
Parasite
Potassium Channel
|
|
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM .
|
-
- HY-16566A
-
-
- HY-130072
-
-
- HY-130047
-
-
- HY-113293
-
-
- HY-N3513R
-
-
- HY-113263
-
-
- HY-113415
-
-
- HY-118774
-
-
- HY-113305
-
-
- HY-A0089
-
-
- HY-B0172B
-
-
- HY-N0488
-
-
- HY-104026B
-
-
- HY-101238
-
-
- HY-N0430A
-
-
- HY-17567
-
-
- HY-149049
-
-
- HY-121360
-
|
|
Microorganisms
Source classification
|
DNA/RNA Synthesis
|
|
Cylindrospermopsin is a cyanotoxin produced by a variety of freshwater cyanobacteria. It is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA .
|
-
- HY-123063
-
-
- HY-17561
-
-
- HY-N15142
-
-
- HY-P3160
-
-
- HY-B0172BR
-
-
- HY-126996
-
-
- HY-W012836
-
-
- HY-118774R
-
-
- HY-N0278
-
-
- HY-119695A
-
-
- HY-17561R
-
-
- HY-N0716
-
-
- HY-N15207
-
-
- HY-N0278A
-
-
- HY-119695AR
-
-
- HY-N14924
-
|
|
Structural Classification
Microorganisms
Ketones, Aldehydes, Acids
Source classification
|
Bacterial
|
|
Oganomycin GA is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria .
|
-
- HY-N14926
-
|
|
Structural Classification
Natural Products
Microorganisms
Ketones, Aldehydes, Acids
Source classification
|
Bacterial
|
|
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .
|
-
- HY-N0648
-
-
- HY-N0648R
-
-
| Cat. No. |
Compare |
Product Name |
Species |
Source |
Compare Products
|
| Products |
|
| Cat. No. |
|
| Species |
|
| Source |
|
| Tag |
|
| Accession |
|
| Gene ID |
|
| Molecular Weight |
|
| Purity |
|
| Endotoxin Level |
|
| Biological Activity |
|
| Appearance |
|
| Formulation |
|
| Storage & Stability |
|
| Shipping |
|
| Free Sample |
Yes
No
|
| Size |
* This product has been "discontinued".
Optimized version of product available:
|
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y0316S
-
|
|
|
Sodium-dodecyl sulfate-d25 is a deuterium labeled Sodium dodecyl sulfate. Sodium dodecyl sulfate is the most widely used of the anionic alkyl sulfate surfactants .
|
-
-
- HY-143645S
-
|
|
|
Glycochenodeoxycholic acid 3-sulfate-d5 (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium .
|
-
-
- HY-132641S
-
|
|
|
Equilin 3-Sulfate-d4 (sodium) is the deuterium labeled Equilin 3-Sulfate sodium salt .
|
-
-
- HY-141931S
-
|
|
|
Glycolithocholic acid 3-sulfate-d4 (sodium) is the deuterium labeled Glycolithocholic acid 3-sulfate .
|
-
-
- HY-141918S
-
|
|
|
Chenodeoxycholic acid 3-sulfate-d4 is the deuterium labeled Chenodeoxycholic acid 3-sulfate .
|
-
-
- HY-113238S1
-
|
|
|
Lithocholic acid 3-sulfate-d4（sodium salt） is the deuterium labeled Lithocholic acid 3-sulfate .
|
-
-
- HY-W743264
-
|
|
|
17β-Estradiol sulfate-d3 sodium (17β-Estradiol 3-sulfate-d3 sodium) is the deuterium labeled 17β-Estradiol sulfate sodium (HY-141672). 17β-Estradiol sulfate sodium, also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
|
-
-
- HY-131524S
-
|
|
|
Taurocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Taurocholic acid 3-sulfate disodium .
|
-
-
- HY-144158S
-
|
|
|
Resveratrol 3-sulfate-d4 (triethylamine) is the deuterium labeled Resveratrol 3-sulfate triethylamine .
|
-
-
- HY-139614S
-
|
|
|
Cholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Cholic acid 3-sulfate disodium .
|
-
-
- HY-141944S
-
|
|
|
Cortisol-21-sulfate-d4 (sodium) is the deuterium labeled Cortisol-21-sulfate .
|
-
-
- HY-113238AS
-
|
|
|
Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium .
|
-
-
- HY-W743434
-
|
|
|
Endosulfan sulfate-d4 is the deuterium labeled Endosulfan sulfate.
|
-
-
- HY-154775S
-
|
|
|
Ethinylestradiol sulfate-d4 is deuterated labeled Ethinylestradiol sulfate.
|
-
-
- HY-141672S1
-
|
|
|
17β-Estradiol sulfate-d4 (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
|
-
-
- HY-W746074S
-
|
|
|
Alternariol-3-sulfate-d3 (ammonium) is deuterium labeled Alternariol 3-Sulfate Ammonium Salt .
|
-
-
- HY-142768S
-
|
|
|
Homovanillic acid sulfate-d3 (sodium) is the deuterium labeled Homovanillic acid sulfate sodium .
|
-
-
- HY-W284558S
-
|
|
|
Sodium hexadecyl sulfate-d33 is the deuterium labeled Sodium hexadecyl sulfate .
|
-
-
- HY-144152S
-
|
|
|
Catechol sulfate-d4 (sodium) is the deuterium labeled Catechol sulfate sodium .
|
-
-
- HY-141931S1
-
|
|
|
Glycolithocholic acid 3-sulfate-d4 disodium is the deuterium labeled Glycolithocholic acid 3-sulfate (HY-113074) .
|
-
-
- HY-141936S
-
|
|
|
Glycochenodeoxychlolic Acid-3-Sulfate-d4 (sodium) is the deuterium labeled Glycochenodeoxychlolic Acid-3-Sulfate .
|
-
-
- HY-141943S
-
|
|
|
Glycocholic Acid-3-Sulfate-d4 (sodium) is the deuterium labeled Glycocholic Acid-3-Sulfate .
|
-
-
- HY-141916S
-
|
|
|
Taurodeoxycholic Acid-3-Sulfate-d4 (Sodium) is the deuterium labeled Taurodeoxycholic Acid-3-Sulfate .
|
-
-
- HY-137255S
-
|
|
|
Taurolithocholic Acid-3-Sulfate-d4 （disodium salt） is the deuterium labeled Taurolithocholic Acid-3-Sulfate .
|
-
-
- HY-141926S
-
|
|
|
Deoxycholic Acid-3-Sulfate Sodium Salt-d4 is the deuterium labeled Deoxycholic Acid-3-Sulfate Sodium Salt .
|
-
-
- HY-141911S
-
|
|
|
Tauroursodeoxycholic Acid-3-Sulfate Sodium Salt-d4 is the deuterium labeled Tauroursodeoxycholic Acid-3-Sulfate Sodium Salt .
|
-
-
- HY-W654121
-
|
|
|
p-Cresol sulfate-d4 (potassium) is deuterium labeled p-Cresyl sulfate (potassium). p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .
|
-
-
- HY-111660S
-
|
|
|
3-Methoxytyramine sulfate-d4 is deuterium labeled 3-Methoxytyramine sulfate.
|
-
-
- HY-66006S1
-
|
|
|
4-Acetaminophen sulfate-d4 is deuterated labeled 4-Acetaminophen sulfate.
|
-
-
- HY-111431AS
-
|
|
|
p-Cresol sulfate-d7 (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].
|
-
-
- HY-W780275S
-
|
|
|
Alternariol-9-monomethylether sulfate-d3 (ammonium) is deuterium labeled Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt .
|
-
-
- HY-66006S
-
|
|
|
4-Acetaminophen sulfate-d3 is the deuterium labeled 4-Acetaminophen sulfate .
|
-
-
- HY-143935S
-
|
|
|
7-Hydroxycoumarin sulfate-d5 is the deuterium labeled 7-Hydroxycoumarin sulfate .
|
-
-
- HY-132429S
-
|
|
|
3-Indoxyl Sulfate-d5 (potassium) is the deuterium labeled 3-Indoxyl Sulfate potassium .
|
-
-
- HY-66006AS
-
|
|
|
4-Acetaminophen sulfate-d3 (potassium) is the deuterium labeled 4-Acetaminophen sulfate potassium .
|
-
-
- HY-143928S
-
|
|
|
4-Hydroxy biphenyl sulfate-d5 (sodium) is the deuterium labeled 4-Hydroxy biphenyl sulfate .
|
-
-
- HY-142641S
-
|
|
|
4-Hydroxy triamterene sulfate-d4 (sodium) is the deuterium labeled 4-Hydroxy triamterene sulfate sodium .
|
-
-
- HY-113293BS
-
|
|
|
Estrone sulfate-d5 (sodium) is the deuterium labeled Estrone sulfate sodium. Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer .
|
-
-
- HY-113293BS1
-
|
|
|
Estrone sulfate-d4 (sodium) is deuterium labeled Estrone sulfate (sodium). Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer .
|
-
-
- HY-146734S
-
|
|
|
17β-Dihydroequilenin 3-sulfate-4,16,16-d3 (sodium) is the deuterium labeled 17β-Dihydroequilenin 3-sulfate-4,16,16.
|
-
-
- HY-126855S
-
|
|
|
Cholic acid 7-sulfate-d4 (7-Sulfocholic acid-d4) is the deuterium labeled Cholic acid 7-sulfate (HY-126855). Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation .
|
-
-
- HY-146712S
-
|
|
|
N-(4-Hydroxyphenyl)acetamide sulfate-d3 (sodium) is the deuterium labeled N-(4-Hydroxyphenyl)acetamide sulfate.
|
-
-
- HY-146736S
-
|
|
|
17β-Dihydroequilin 3-sulfate-2,4,16,16-d4 (sodium) is the deuterium labeled 17β-Dihydroequilin 3-sulfate-2,4,16,16.
|
-
-
- HY-B1370S
-
|
|
|
Hydroxychloroquine-d4 (sulfate) is the deuterium labeled Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .
|
-
-
- HY-B1018AS
-
|
|
|
Phenelzine-d5 (sulfate) is the deuterium labeled Phenelzine sulfate .
|
-
-
- HY-143831S
-
|
|
|
Cefepime-d8 (sulfate) is the deuterium labeled Cefepime sulfate .
|
-
-
- HY-B1134AS
-
|
|
|
Imazalil-d5 (sulfate) is the deuterium labeled Imazalil sulfate .
|
-
-
- HY-15283AS
-
|
|
|
(±)-Clopidogrel-d7 (sulfate) is the deuterium labeled (±)-Clopidogrel sulfate .
|
-
-
- HY-107867S
-
|
|
|
Clopidogrel-d4 (sulfate) is the deuterium labeled Clopidogrel sulfate .
|
-
-
- HY-107867S3
-
|
|
|
(Rac)-Clopidogrel-d3 (sulfate) is deuterium labeled Clopidogrel (sulfate).
|
-
- HY-150779S
-
|
|
|
Choline-d13 (sulfate) is the deuterium labeled Choline sulfate .
|
-
- HY-W654100
-
|
|
|
Cefepime-d3 (sulfate) is deuterium labeled Cefepime (sulfate) .
|
-
- HY-W010973S
-
|
|
|
5-Hydroxytryptamine-d4 creatinine sulfate monohydrate is the deuterium labeled 5-Hydroxytryptamine creatinine sulfate monohydrate. 5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.
|
-
- HY-113441S
-
|
|
|
3-Methoxy-4-Hydroxyphenylglycol sulfate-d3 potassium is the deuterium labeled 3-Methoxy-4-Hydroxyphenylglycol sulfate potassium .
|
-
- HY-W011910S
-
|
|
|
Potassium 1H-indol-3-yl sulfate-d4 (potassium) is the deuterium labeled Potassium 1H-indol-3-yl sulfate. Potassium 1H-indol-3-yl sulfate is an endogenous metabolite.
|
-
- HY-141921S
-
|
|
|
Dehydroepiandrosterone sulfate sodium salt-d6 (DHEA sulfate sodium salt-d6; Prasterone sulfate sodium salt-d6) is the deuterium labeled Dehydroepiandrosterone sulfate sodium salt (HY-B0765). Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-113296S
-
|
|
|
Indoxyl Sulfate Potassium Salt- 13C6 is the 13C labeled Indoxyl Sulfate Potassium Salt .
|
-
- HY-111355S
-
|
|
|
Cholesterol sulfate sodium-d7 is the deuterium labeled Cholesterol sulfate sodium .
|
-
- HY-166934S
-
|
|
|
Endosulfan- 13C9 (sulfate) is 13C labeled Endosulfan (sulfate) .
|
-
- HY-W769792
-
|
|
|
Methotrexate-d3 Diglutamate TFA Sulfate is the deuterium labeled Methotrexate Diglutamate TFA Sulfate.
|
-
- HY-154768S
-
|
|
|
Ciprofloxacin-piperazinyl-N-sulfate-d8 is deuterated labeled Ciprofloxacin-piperazinyl-N-sulfate.
|
-
- HY-W744217
-
|
|
|
7-Hydroxy coumarin sulfate-d5 potassium (7-HCS-d5 potassium) is the deuterium labeled 7-Hydroxy coumarin sulfate potassium (HY-129977). 7-Hydroxy coumarin sulfate (7-HCS) potassium is a metabolite of 7-Ethoxycoumarin (HY-133091) .
|
-
- HY-17459S
-
|
|
|
Clopidogrel-d3 (hydrogen sulfate) is the deuterium labeled Clopidogrel hydrogen sulfate . Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
|
-
- HY-W020772S
-
|
|
|
Aminoguanidine sulfate- 13C, 15N2 is the 13C, 15N labeled Aminoguanidine sulfate.
|
-
- HY-W020772S1
-
|
|
|
Aminoguanidine sulfate- 13C, 15N4 is the 13C, 15N labeled Aminoguanidine sulfate.
|
-
- HY-W714568
-
|
|
|
4-Hydroxychlorpropham Sulfate Sodium Salt-d7 is the deuterium labeled 4-Hydroxychlorpropham Sulfate Sodium Salt.
|
-
- HY-113416AS
-
|
|
|
Dehydroepiandrosterone sulfate sodium dihydrate-d6 sodium dihydrate is the deuterium labeled Dehydroepiandrosterone sulfate sodium dihydrate. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium dihydrate is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium dihydrate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium dihydrate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium dihydrate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium dihydrate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
|
-
- HY-N0488S2
-
|
|
|
Vincristine-d6 (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
|
-
- HY-W751109
-
|
|
|
Methyl carbamimidothioate sulfate- 13C is the 13C-labeled Methyl carbamimidothioate sulfate (HY-W089554).
|
-
- HY-154744S
-
|
|
|
Trimegestone sulfate pyridinium salt- 13C,d3 is 13C and deuterated labeled Trimegestone sulfate pyridinium salt.
|
-
- HY-111660S1
-
|
|
|
3-Methoxytyramine sulfate- 13C,d3 is deuterium labeled 3-Methoxytyramine sulfate.
|
-
- HY-N0488S
-
|
|
|
Vincristine-d3 (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM .
|
-
- HY-N0488S1
-
|
|
|
Vincristine-d3-ester (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM .
|
-
- HY-104026CS
-
|
|
|
L-Kynurenine- 13C10 (sulfate hemihydrate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .
|
-
- HY-W020772AS1
-
|
|
|
Aminoguanidine- 13C, 15N4 sulfate (1:2) is the 13C, 15N labeled Aminoguanidine sulfate (1:2).
|
-
- HY-W020772AS
-
|
|
|
Aminoguanidine- 13C, 15N2 sulfate (1:2) is the 13C, 15N labeled Aminoguanidine sulfate (1:2).
|
-
- HY-101238S
-
|
|
|
Agmatine-d8 sulfate is a deuterium labeled Agmatine sulfate (HY-101238). Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor .
|
-
- HY-104026BS
-
|
|
|
L-Kynurenine-13C10 (sulfate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .
|
-
- HY-W766913
-
|
|
|
Moxifloxacin (N-Sulfate Disodium)- 13C,d3 is the deuterium labeled and 13C-labeled Moxifloxacin (N-Sulfate Disodium).
|
-
- HY-104026S5
-
|
|
|
L-Kynurenine-13C10 sulfate hydrate is the C13 labeled L-Kynurenine sulfate hydrate. L-Kynurenine is an aryl hydrocarbon receptor agonist .
|
-
- HY-W096997S
-
|
|
|
Sodium octyl sulfate(Reagent for Ion-Pair Chromatography,99%)-d17 is the deuterium labeled Sodium octyl sulfate(Reagent for Ion-Pair Chromatography,99%)[1].
|
-
- HY-B0394S
-
|
|
|
Atropine-d5 is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect .
|
-
- HY-148682S2
-
|
|
|
18β-Glycyrrhetyl-3-O-sulfate-d3 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682) .
|
-
- HY-148682S1
-
|
|
|
18β-Glycyrrhetyl-3-O-sulfate-d2 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682) .
|
-
- HY-W754114
-
|
|
|
Nalmefene Sulfate-d3 is the deuterium labeled Nalmefene (HY-107744). Nalmefene is a BBB-penetrable opioid receptor modulator. Nalmefene is an antagonist of MOR and DOR, and a partial agonist of KOR. Nalmefene has anti-inflammatory and neuroprotective activities. Nalmefene can be used in the research of reducing alcohol-dependent disorders .
|
-
- HY-W744419
-
|
|
|
Epiandrosterone sulfate sodium salt-d5 is the deuterium labeled Sodium (3S,5S,8R,9S,10S,13S,14S)-10,13-dimethyl-17-oxohexadecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfate (HY-W707903).
|
-
- HY-W653718
-
|
|
|
o-Cresol-d7 is the deuterium labeled o-Cresol (HY-156199). o-Cresol sulfate is a biomarker related to CAR T cell-independent and dependent metabolic and inflammatory .
|
-
- HY-Y0261AS
-
|
|
|
Ammonium sulphate-d8 is the deuterium labeled Ammonium sulphate,≥99.0%,AR . Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology .
|
-
- HY-W338810S
-
|
|
|
S-(5'-Adenosyl)-L-methionine- 13C5 sulfate is a 13C-labeled S-(5'-Adenosyl)-L-methionine. S-(5'-Adenosyl)-L-methionine is a methyl donor and cofactor .
|
-
- HY-Y0261AS1
-
|
|
|
Ammonium sulphate,≥99.0%,AR- 15N2 is the deuterium labeled Ammonium sulphate,≥99.0%,AR . Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology .
|
-
- HY-W031727S
-
|
|
|
Hydroxychloroquine-d4-1 (sulfate) is the deuterium labeled Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .
|
-
- HY-W753473
-
|
|
|
4-Ethylphenol-d9 is the deuterium labeled 4-Ethylphenol (HY-W012836). 4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine. 4-Ethylphenol is a phenolic compound that can be synthesized by intestinal flora. 4-Ethylphenol will be converted to 4-ethylphenyl sulfate (HY-W674241) by Lactobacillus plantarum .
|
-
- HY-119695S
-
|
|
|
Simvastatin acid-d6 (Tenivastatin-d6) is deuterium labeled Simvastatin acid. Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-119695AS
-
|
|
|
Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-119695AS1
-
|
|
|
Simvastatin acid-d9 ammonium is deuterated labeled Simvastatin acid ammonium (HY-119695A). Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
|
-
- HY-107867S1
-
|
|
|
(Rac)-Clopidogrel hydrogen-d9 sulfate is the deuterium labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .
|
-
- HY-17412S1
-
|
|
|
Minocycline-d6 sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .
|
-
- HY-107867S2
-
|
|
|
Clopidogrel- 13C,d3 sulfate is the deuterium and 13C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-157424
-
|
PAPS tetralithium salt
|
|
Nucleotides and their Analogs
A
|
|
3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt (PAPS tetralithium salt) is the cosubstrate and the source of sulfonic acid groups in sulfation reactions. 3′-Phosphoadenosine 5′-phosphosulfate tetralithium salt is important for maintaining sulfation balance in living organisms .
|
-
- HY-Y0316
-
|
Sodium lauryl sulfate; Laurylsulfuric acid sodium salt
|
|
Emulsifiers
Surfactants
|
|
Sodium dodecyl sulfate is an anionic surfactant commonly used as a detergent, emulsifier, and protein denaturant in various industrial processes, especially in the production of personal care products, cleaners, and laboratory reagents. Sodium dodecyl sulfate has unique chemical properties that make it an effective ingredient in many applications, helping to reduce surface tension and enhance cleaning power.
|
-
- HY-B0172B
-
|
|
|
Cholesterol
|
|
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .
|
-
- HY-164090
-
-
- HY-160067
-
|
|
|
Aptamers
|
|
T18.3 aptamer sodium is an anticoagulant RNA aptamer targeting FV/Va and eliminates the interaction of FV/FVa with phospholipid membranes. T18.3 aptamer sodium exhibits clinically relevant anticoagulant activity in plasma and whole blood and acts synergistically with low molecular weight heparin. The anticoagulant activity of T18.3 aptamer sodium is effectively and rapidly reversed by protamine sulfate .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
