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diphosphate

" in MedChemExpress (MCE) Product Catalog:

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226

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Recombinant Proteins

Isotope-Labeled Compounds

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Targets Recommended: UGT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W749117

*Inosine 5′-diphosphate* sodium**	Endogenous Metabolite	Metabolic Disease
Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .

HY-W010918

Adenosine 5'-diphosphate 3 Publications Verification Adenosine diphosphate; ADP	Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918R

*Adenosine 5'-diphosphate* (Standard)** Adenosine diphosphate (Standard); ADP (Standard)	Reference Standards Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

HY-106254A

Vapendavir diphosphate 4 Publications Verification BTA798 diphosphate	Enterovirus	Infection Inflammation/Immunology
Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC₅₀ values of 0.5-1.4 μM in different EV71 strains .

HY-16582

Sonidegib diphosphate 5+ Cited Publications Erismodegib diphosphate; LDE225 diphosphate; NVP-LDE225 diphosphate	Smo	Cancer
Sonidegib diphosphate (Erismodegib diphosphate) is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-B1831A

Oritavancin diphosphate 2 Publications Verification LY333328 diphosphate	Bacterial Antibiotic	Infection Inflammation/Immunology
Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate	Endogenous Metabolite	Others
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W008940R

*Cytidine 5'-diphosphate* disodium salt (Standard)** Cytidine diphosphate disodium (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W008940

*Cytidine 5'-diphosphate* disodium salt** Cytidine diphosphate disodium	Endogenous Metabolite	Metabolic Disease
Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W552525

*Deoxyadenosine diphosphate* sodium**	Phosphorylase	Infection
Deoxyadenosine diphosphate sodium is a nucleoside diphosphate, in which the nucleoside is deoxyadenosine. Deoxyadenosine diphosphate sodium participates in DNA synthesis and repair. Deoxyadenosine diphosphate sodium acts as the inhibitor of polynucleotide phosphorylase, interfers with the polymerization of ADP and CDP .

HY-P2881

*Nucleoside diphosphate* kinase** Nucleoside 5′-diphosphate kinase	Biochemical Assay Reagents	Others
Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0199

*Adenosine 5'-diphosphate* disodium** 3 Publications Verification	Endogenous Metabolite	Cardiovascular Disease
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-D0882

*Adenosine 5'-diphosphate* dicyclohexylammonium**	Biochemical Assay Reagents	Cardiovascular Disease
Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate dicyclohexylammonium induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors .

HY-B1831AR

*Oritavancin diphosphate* (Standard)** LY333328 diphosphate (Standard)	Reference Standards Bacterial Antibiotic	Infection Inflammation/Immunology
Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .

HY-D0199R

*Adenosine 5'-diphosphate* disodium (Standard)**	Endogenous Metabolite	Cardiovascular Disease
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-W010791

*Adenosine 5'-diphosphate* sodium salt** 3 Publications Verification	Endogenous Metabolite	Others
Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors .

HY-131576

Thymidine 5′-diphosphate dTDP	Endogenous Metabolite	Infection
Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-131576A

*Thymidine 5′-diphosphate* sodium** dTDP sodium	Endogenous Metabolite	Infection
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-113066

Guanosine 5'-diphosphate GDP	Endogenous Metabolite Potassium Channel	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113400S3

*Cytidine diphosphate-d13 dilithium*	Isotope-Labeled Compounds Endogenous Metabolite	Others
Cytidine diphosphate-d₁₃ dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-135811A

Desethyl chloroquine diphosphate 2 Publications Verification	Parasite Toll-like Receptor (TLR) Autophagy	Infection
Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity .

HY-135811AR

*Desethyl chloroquine diphosphate* (Standard)**	Parasite Toll-like Receptor (TLR) Autophagy	Infection
Desethyl chloroquine (diphosphate) (Standard) is the analytical standard of Desethyl chloroquine (diphosphate). This product is intended for research and analytical applications. Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity .

HY-113066AR

*Guanosine 5'-diphosphate* disodium salt (Standard)**	Endogenous Metabolite Potassium Channel	Neurological Disease Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-168165

Adefovir diphosphate	Endogenous Metabolite	Cancer
Adefovir diphosphate is an antiviral compound with activity against hepatitis B virus (HBV). Adefovir diphosphate blocks the replication of HBV by inhibiting reverse transcriptase. Adefovir diphosphate has also shown activity against other viruses such as herpes viruses and human immunodeficiency virus. Adefovir diphosphate is used as an effective inhibitory option in the suppression of chronic hepatitis B. The mechanism of action of Adefovir diphosphate involves blocking the autophosphorylation of growth factor receptors, thereby potentially reducing the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B .

HY-115581A

*Thymidine 3',5'-diphosphate* tetrasodium** Deoxythymidine 3′,5′-diphosphate tetrasodium; pdTp tetrasodium	Apoptosis MicroRNA	Cancer
Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the MicroRNA regulatory complex RISC subunit) and [3,5- ²H₂] tyrosyl nuclease. Thymidine 3',5'-diphosphate tetrasodium has anti-tumor activity and can also be used as a catalyst in biochemical reactions .

HY-113359AS

*Uridine 5'-diphosphate-d12 dilithium*	Isotope-Labeled Compounds	Others
Uridine 5'-diphosphate-d₁₂ dilithium is the deuterium labeled Uridine 5'-diphosphate .

HY-N7740

*Adenosine 2',5'-diphosphate* sodium**	P2Y Receptor Endogenous Metabolite	Others
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors .

HY-125072

Arabinose 1,5-diphosphate	Phosphatase	Others
Arabinose 1,5-diphosphate serves as an inhibitor of bisphosphatase activity.

HY-10229R

*Motesanib Diphosphate* (Standard)** AMG 706 diphosphate (Standard)	Reference Standards c-Kit VEGFR	Cancer
Motesanib (Diphosphate) (Standard) is the analytical standard of Motesanib (Diphosphate). This product is intended for research and analytical applications. Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.

HY-136548

Tenofovir diphosphate TFV-DP	Reverse Transcriptase HIV	Infection Inflammation/Immunology
Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (K_i = 1.55 μM) and RNA (K_i = 0.022 μM). Tenofovir diphosphate can be used for the research of AIDS .

HY-D0199S

*Adenosine 5′-diphosphate-15N5 disodium*	Endogenous Metabolite	Others
Adenosine- ¹⁵N₅ 5′-diphosphate (disodium salt) is the ¹⁵N labeled Adenosine 5'-diphosphate disodium salt .

HY-W010820

*Uridine 5'-diphosphate* sodium salt** 1 Publications Verification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52) and a potent P2Y₁₄ antagonist (pEC₅₀=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-128606

*Thiamine diphosphate* analog 1**	Drug Derivative	Metabolic Disease
Thiamine diphosphate analog 1 is an analog of Thiamine diphosphate . Thiamine diphosphate is the active form of vitamin B₁. Thiamine diphosphate a universal cofactor involved in pivotal cellular pathways .

HY-113066B

*Guanosine 5'-diphosphate* ditromethamine** GDP ditromethamine	Potassium Channel Endogenous Metabolite	Inflammation/Immunology
Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-12651S

Primaquine-d3 diphosphate	Isotope-Labeled Compounds Parasite	Infection
Primaquine-d₃ (diphosphate) is the deuterium labeled Primaquine diphosphate. Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale .

HY-137243

*Adenosine 3',5'-diphosphate* disodium**	Endogenous Metabolite	Others
Adenosine 3',5'-diphosphate disodium is an hydroxysteroid sulfotransferases inhibitor .

HY-113066A

*Guanosine 5'-diphosphate* disodium salt** 2 Publications Verification GDP disodium salt	Endogenous Metabolite Potassium Channel	Neurological Disease Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-W008915R

*Cytidine 5'-diphosphate* trisodium salt (Standard)** CDP (Standard)	Reference Standards DNA/RNA Synthesis	Metabolic Disease
Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

HY-135867F

*NHC-diphosphate* triammonium** 1 Publications Verification	Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV	Infection
NHC-diphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC-diphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA .

HY-113400S

*Cytidine diphosphate-15N3 dilithium*	Isotope-Labeled Compounds Endogenous Metabolite	Others
Cytidine diphosphate- ¹⁵N₃ dilithium is ¹⁵N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-W010918S3

*Adenosine 5'-diphosphate-13C5* Adenosine diphosphate-¹³C₅; ADP-¹³C₅	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate- ¹³C₅ (Adenosine diphosphate- ¹³C₅) is the ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

HY-113359AS3

*Uridine 5'-diphosphate-15N2 dilithium*	Isotope-Labeled Compounds Endogenous Metabolite P2Y Receptor	Others
Uridine 5'-diphosphate- ¹⁵N₂ dilithium is ¹⁵N labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-W008915

*Cytidine 5'-diphosphate* trisodium salt** CDP	DNA/RNA Synthesis	Metabolic Disease
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .

HY-113400S1

*Cytidine diphosphate-13C9 dilithium*	Isotope-Labeled Compounds Endogenous Metabolite	Others
Cytidine diphosphate- ¹³C₉ dilithium is ¹³C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113359AS1

*Uridine 5'-diphosphate-13C9 dilithium*	Isotope-Labeled Compounds Endogenous Metabolite P2Y Receptor	Others
Uridine 5'-diphosphate- ¹³C₉ dilithium is ¹³C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-113359

Uridine 5'-diphosphate	P2Y Receptor Endogenous Metabolite	Others
Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-112889

Oxythiamine diphosphate	Transketolase	Metabolic Disease
Oxythiamin diphosphate is a potent transketolase (TK) inhibitor .

HY-164839A

*Clofarabine-5'-diphosphate* trisodium** Clofarabine-DP trisodium	DNA/RNA Synthesis	Cancer
Clofarabine-5'-diphosphate trisodium (Clofarabine-DP trisodium) is the trisodium salt form of Clofarabine-5'-diphosphate (HY-164839). Clofarabine-5'-diphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-diphosphate trisodium can be further phorphorylated into Clofarabine-5'-triphosphate, and exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .

HY-W010832

*Uridine-5'-diphosphate* disodium salt** 1 Publications Verification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-164839

Clofarabine-5'-diphosphate Clofarabine-DP	DNA/RNA Synthesis	Cancer
Clofarabine-5'-diphosphate (Clofarabine-DP) is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-diphosphate can be further phorphorylated into Clofarabine-5'-triphosphate, and exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .

Cat. No.	Product Name	Type

HY-D0199

*Adenosine 5'-diphosphate* disodium** 3 Publications Verification	Biochemical Assay Reagents
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-Y1918

Potassium diphosphate tetra-Potassium pyrophosphate	Buffer Reagents
Potassium diphosphate (tetra-Potassium pyrophosphate) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-113066C

Guanosine 5'-diphosphate (sodium), 96% (HPLC)

2 Publications Verification

GDP (sodium), Type I, 96% (HPLC)

Gene Sequencing and Synthesis

Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-W010854

*2'-Deoxyadenosine 5'-di-phos-phate* disodium** dADP disodium	Gene Sequencing and Synthesis
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-D0199R

Adenosine 5'-diphosphate disodium (Standard)

Biochemical Assay Reagents

Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-125954A

Uridine diphosphate glucuronic acid ammonium

UDP-α-D-glucuronic acid ammonium

Gene Sequencing and Synthesis

Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .

HY-164112

*1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium* 18:1 CDP DG	Drug Delivery
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate .

HY-163973

α-D-Glucopyranosyl β-D-arabino-2-hexulofuranosidonic acid	Carbohydrates
Clindamycin 2,4-diphosphate is a biochemical assay reagent.

HY-163967

Clindamycin 2,4-diphosphate	Cell Assay Reagents
Arlacel A is a biochemical assay reagent.

HY-W127689

Bis(tetrabutylammonium) dihydrogen pyrophosphate Bis(tetrabutylammonium) dihydrogen diphosphate	Biochemical Assay Reagents
Bis(tetrabutylammonium) Dihydrogen Pyrophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010918R

*Adenosine 5'-diphosphate* (Standard)** Adenosine diphosphate (Standard); ADP (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder	Reference Standards Endogenous Metabolite
Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

HY-131576A

*Thymidine 5′-diphosphate* sodium** dTDP sodium	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-N7740

*Adenosine 2',5'-diphosphate* sodium**	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	P2Y Receptor Endogenous Metabolite
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors .

HY-W010820

*Uridine 5'-diphosphate* sodium salt** 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine 5'-diphosphate sodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52) and a potent P2Y₁₄ antagonist (pEC₅₀=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W008940R

*Cytidine 5'-diphosphate* disodium salt (Standard)** Cytidine diphosphate disodium (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Reference Standards
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-D0199R

*Adenosine 5'-diphosphate* disodium (Standard)**	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-131576

Thymidine 5′-diphosphate dTDP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-113066

Guanosine 5'-diphosphate GDP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite Inflammation/Immunology Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113066AR

*Guanosine 5'-diphosphate* disodium salt (Standard)**	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-113066A

*Guanosine 5'-diphosphate* disodium salt** 2 Publications Verification GDP disodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-W008915R

*Cytidine 5'-diphosphate* trisodium salt (Standard)** CDP (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards DNA/RNA Synthesis
Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

HY-135867F

*NHC-diphosphate* triammonium** 1 Publications Verification	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV
NHC-diphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC-diphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA .

HY-W008915

*Cytidine 5'-diphosphate* trisodium salt** CDP	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .

HY-113359

Uridine 5'-diphosphate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	P2Y Receptor Endogenous Metabolite
Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-W010832

*Uridine-5'-diphosphate* disodium salt** 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y₆ receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-135867D

NHC-diphosphate 1 Publications Verification	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV
NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) .

HY-114327

D-Ribose 1,5-diphosphate R15P	Microorganisms Source classification	Others
D-Ribose 1,5-diphosphate (R15P) is a pentaglucose, it plays an important role in the Calvin cycle of photosynthesis .

HY-113066C

*Guanosine 5'-diphosphate* (sodium), 96% (HPLC)** 2 Publications Verification GDP (sodium), Type I, 96% (HPLC)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-114295A

*Geranyl diphosphate* triammonium** Geranyl pyrophosphate triammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Geranyl diphosphate triammonium is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl diphosphate triammonium plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .

HY-N11102

*Thymidine-5'-diphosphate-L-rhamnose*	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Leguminosae Source classification Vigna radiata (L.) Wilczek Plants Endogenous metabolite	Others
Thymidine-5'-diphosphate-L-rhamnose disodium can be isolated from Occhromonas malhamensis .

HY-125954

*Uridine diphosphate* glucuronic acid** UDP-α-D-glucuronic acid	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .

HY-141472

*7-Methylguanosine 5'-diphosphate* sodium** 7-Methyl-GDP sodium; m7GDP sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

HY-125954A

*Uridine diphosphate* glucuronic acid ammonium** UDP-α-D-glucuronic acid ammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .

HY-114295

Geranyl diphosphate Geranyl pyrophosphate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Geranyl diphosphate is a key intermediate in the isoprenoid biosynthesis pathway (IBP). HY-114295 plays key roles in cellular metabolism and is responsible for the production of both sterol and non-sterol isoprenoids .

HY-134556

2'-Hydroxyflavanone	Structural Classification Flavonoids Mimosa pudica Linn. Leguminosae Flavonones Source classification Plants	Apoptosis
2'-Hydroxyflavanone is a flavanone that can inhibit cancer cell proliferation, induce apoptosis, and reduce inflammation. 2'-Hydroxyflavanone shows inhibitory effect on platelet aggregation caused by two inducers with IC₅₀s 47.8 μM arachidonic acid (AA) and 147.2 μM aenosine diphosphate (ADP) .

HY-113037

(E/Z)-Farnesyl pyrophosphate (E/Z)-Farnesyl diphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	TRP Channel Endogenous Metabolite
(E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .

HY-165154

Cyclamidomycin Desdanine; Pyracrimycin A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Fungal Pyruvate Kinase Oxidative Phosphorylation
Cyclamidomycin (Desdanine) is an acrylamide antibiotic with antibacterial activity. Cyclamidomycin inhibits *nucleoside diphosphate* kinase and pyruvate kinase** (in E. coli) and oxidative phosphorylation in rat liver mitochondria. Cyclamidomycin is active against S. aureus, M. flavus, S. lutea, B. subtilis, E. coli, S. flexneri, S. typhosa, P. vulgaris, and K. pneumoniae (MICs=3.12-25 mg/ml) .

HY-B0739R

Citicoline (Standard) Cytidine diphosphate-choline (Standard); CDP-Choline (Standard); Cytidine 5'-diphosphocholine (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Animals Other Alkaloids Source classification Plants Endogenous metabolite	Reference Standards Apoptosis Endogenous Metabolite Caspase Reactive Oxygen Species (ROS)
Citicoline (Cytidine diphosphate-choline) (Standard) is the analytical standard of Citicoline. This product is intended for research and analytical applications. Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study.

HY-B0445

NAD+ Maximum Cited Publications 32 Publications Verification β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-130573

DMAPP Dimethylallyl diphosphate	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Populus tremula Salicaceae	Others
DMAPP (Dimethylallyl pyrophosphate) is an isoprenoid precursor. DMAPP, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms .

HY-A0129

Histamine phosphate 10+ Cited Publications Histamine diphosphate	Alkaloids Structural Classification Neurological Disease Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-N1717

2-Acetylbenzoic acid	Structural Classification Natural Products Ketones, Aldehydes, Acids Impatiens balsamina Linn. Source classification Balsaminaceae Plants	Platelet-activating Factor Receptor (PAFR)
2-Acetylbenzoic acid, a Benzoic acid (HY-N0216) derivative, is a weak platelet aggregation inhibitor. 2-Acetylbenzoic acid inhibits Adenosine 5'-diphosphate (ADP, HY-W010918)-induced platelet aggregation .

HY-N14932

Aggreceride A	Structural Classification Natural Products Microorganisms Source classification	Platelet-activating Factor Receptor (PAFR)
Aggreceride A is a platelet aggregation inhibitor. Aggreceride A shows an inhibitory activity against aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590) and PAF (platelet activating factor), but was less active against aggregation induced by collagen .

HY-A0129R

Histamine phosphate (Standard) Histamine diphosphate (Standard)	Alkaloids Structural Classification Other Alkaloids Source classification Endogenous metabolite	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine phosphate (Standard) is the analytical standard of Histamine phosphate (HY-A0129). This product is intended for research and analytical applications. Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-N14933

Aggreceride B	Structural Classification Natural Products Microorganisms Source classification	Platelet-activating Factor Receptor (PAFR)
Aggreceride B is a platelet aggregation inhibitor. Aggreceride B shows an inhibitory activity against aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590) and PAF (platelet activating factor), but was less active against aggregation induced by collagen .

HY-N14934

Aggreceride C	Structural Classification Natural Products Microorganisms Source classification	Platelet-activating Factor Receptor (PAFR)
Aggreceride C is a platelet aggregation inhibitor. Aggreceride C shows an inhibitory activity against aggregation induced by Adenosine 5'-diphosphate (ADP) (HY-W010918), Arachidonic acid (HY-109590) and PAF (platelet activating factor), but was less active against aggregation induced by collagen .

HY-124723

Gerfelin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Farnesyl Transferase
Gerfelin inhibits *geranylgeranyl diphosphate* synthase (GGPP synthase) activity with an IC₅₀** of 3.5 μg/mL .

HY-113037C

Farnesyl pyrophosphate ammonium Farnesyl diphosphate ammonium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	TRP Channel Endogenous Metabolite
Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .

HY-N8246

2',3'-cUMP sodium Uridine-2', 3'-cyclic monophosphate sodium salt	Structural Classification Natural Products Microorganisms Source classification	Others
2',3'-cUMP sodium (Uridine-2', 3'-cyclic monophosphate sodium salt) is a competitive inhibitor of *dip-nitrophenyl diphosphate* hydrolysis** .

HY-N13135

Kadsutherin G	Structural Classification Kadsura heteroclita (Roxb.) Craib Source classification Lignans Phenylpropanoids Plants Schisandraceae	Others
Kadsutherin G (compound 3) is a lignin isolated from Kadsura. Kadsutherin G inhibits adenosine diphosphate (ADP)-induced platelet aggregation by 33.1 % .

HY-B0739

Citicoline 4 Publications Verification Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Animals Other Alkaloids Source classification Plants Endogenous metabolite	Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS) Caspase
Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study .

HY-B0739A

Citicoline sodium 4 Publications Verification Cytidine diphosphate-choline sodium; CDP-Choline sodium; Cytidine 5'-diphosphocholine sodium	Alkaloids Structural Classification Microorganisms other families Animals Other Alkaloids Source classification Plants Endogenous metabolite	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Caspase
Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study .

HY-N13134

Kadsutherin F	Structural Classification Kadsura heteroclita (Roxb.) Craib Source classification Lignans Phenylpropanoids Plants Schisandraceae	Others
Kadsutherin F (compound 2) is a lignin that can be isolated from Kadsura. Kadsutherin F has an inhibitory effect on adenosine diphosphate (ADP)-induced platelet aggregation with an inhibition rate of 49.47% .

HY-N4266

Vinaginsenoside R8	Cardiovascular Disease Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Araliaceae	Others
Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC₅₀=25.18 μM) .

HY-N9474

Mevalonic acid 5-pyrophosphate tetralithium 5-Diphosphomevalonic acid tetralithium; Mevalonic acid 5-diphosphate tetralithium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway .

HY-134891

HMBPP lithium (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium	Structural Classification Natural Products Microorganisms Source classification	Nuclear Factor of activated T Cells (NFAT)
HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .

HY-17026E

Gemcitabine triphosphate trisodium dFdCTP trisodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Gemcitabine triphosphate (trisodium) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells .

HY-B0739AR

Citicoline sodium (Standard) Cytidine diphosphate-choline sodium (Standard); CDP-Choline sodium (Standard); Cytidine 5'-diphosphocholine sodium (Standard)	Alkaloids Structural Classification Microorganisms other families Animals Other Alkaloids Source classification Plants Endogenous metabolite	Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Caspase
Citicoline sodium (Standard) is the analytical standard of Citicoline sodium. This product is intended for research and analytical applications. Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study.

HY-17026A

Gemcitabine triphosphate dFdCTP	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
Gemcitabine triphosphate (dFdCTP) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells .

Species:	Human (10)
Tag:	His (10) GST (1)
Source:	HEK293 (2) Sf9 insect cells (1) P. pastoris (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P72193

	FDFT1 Protein, Human (His) DGPT; ERG9; Farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; SQS; Squalene synthase; Squalene synthetase; SS	Human	E. coli
	FDFT1 is a key enzyme in cellular metabolism responsible for coordinating the condensation of two farnesyl pyrophosphate (FPP) molecules, a key step in sterol biosynthesis. The process proceeds in two distinct steps: First, two FPP molecules react to form the stable squalene diphosphate intermediate (PSQPP), releasing protons and inorganic diphosphate. FDFT1 Protein, Human (His) is the recombinant human-derived FDFT1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70299

	NME1/NDPKA Protein, Human (His) rHuNucleoside diphosphate kinase A/NDPKA, His; Nucleoside diphosphate Kinase A; NDK A; NDP Kinase A; Granzyme A-Activated DNase; GAAD; Metastasis Inhibition Factor nm23; Tumor Metastatic Process-Associated Protein; nm23-H1; NME1; NDPKA; NM23	Human	E. coli
	The NME1/NDPKA protein plays a crucial role in the synthesis of nucleoside triphosphates and exhibits multiple activities, including nucleoside diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease functions. NME1/NDPKA Protein, Human (His) is the recombinant human-derived NME1/NDPKA protein, expressed by E. coli , with N-6*His labeled tag.

HY-P76534

	p53R2 Protein, Human (His) Ribonucleoside-diphosphate reductase subunit M2 B; p53R2; RRM2B	Human	E. coli
	The p53R2 protein is essential for cell survival and operates in a p53/TP53-dependent manner to support DNA repair. It provides essential deoxyribonucleotides for DNA repair, particularly in G1 or G2 arrested cells, and contains an iron-tyrosyl radical center critical for catalysis. p53R2 Protein, Human (His) is the recombinant human-derived p53R2 protein, expressed by E. coli , with N-His labeled tag.

HY-P71267

	RRM2 Protein, Human (HEK293, His) Ribonucleoside-diphosphate Reductase Subunit M2; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RRM2; RR2	Human	HEK293
	RRM2 Protein, pivotal in DNA synthesis, catalyzes deoxyribonucleotide biosynthesis from ribonucleotide precursors, ensuring vital building blocks for DNA replication. Beyond nucleotide biosynthesis, RRM2 inhibits Wnt signaling, indicating involvement in regulating this crucial cellular pathway. RRM2 Protein, Human (HEK293, His) is the recombinant human-derived RRM2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70903

	IDI2 Protein, Human (His) Isopentenyl-diphosphate Delta-Isomerase 2; Isopentenyl Pyrophosphate Isomerase 2; IPP Isomerase 2; IPPI2; IDI2	Human	E. coli
	IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (His) is the recombinant human-derived IDI2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70903A

	IDI2 Protein, Human (C-His) Isopentenyl-diphosphate Delta-Isomerase 2; Isopentenyl Pyrophosphate Isomerase 2; IPP Isomerase 2; IPPI2; IDI2	Human	E. coli
	IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (C-His) is the recombinant human-derived IDI2 protein, expressed by E. coli , with C-8*His labeled tag.

HY-P70224

	GGPS1 Protein, Human (His) rHuGeranylgeranyl pyrophosphate synthase/GGPS1, His; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; GGPPSase; (2E; 6E)-Farnesyl diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl diphosphate Synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate Synthase; Geranyltranstransferase; GGPS1	Human	E. coli
	The GGPS1 protein is responsible for catalyzing the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) to dimethylallyl pyrophosphate (DMAPP) to synthesize geranylgeranyl pyrophosphate. This compound is an important precursor for the biosynthesis of carotenoids and geranylated proteins. GGPS1 Protein, Human (His) is the recombinant human-derived GGPS1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702577

	GGPS1 Protein, Human (HEK293, His) rHuGeranylgeranyl pyrophosphate synthase/GGPS1, His; Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; GGPPSase; (2E; 6E)-Farnesyl diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl diphosphate Synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate Synthase; Geranyltranstransferase; GGPS1	Human	HEK293
	The GGPS1 protein is responsible for catalyzing the trans-addition of three molecules of isopentenyl pyrophosphate (IPP) to dimethylallyl pyrophosphate (DMAPP) to synthesize geranylgeranyl pyrophosphate. This compound is an important precursor for the biosynthesis of carotenoids and geranylated proteins. GGPS1 Protein, Human (HEK293, His) is the recombinant human-derived GGPS1, expressed by HEK293, with C-His labeled tag. The total length of GGPS1 Protein, Human (HEK293, His) is 300 a.a..

HY-P74591

	RRM1 Protein, Human (sf9, His-GST) Ribonucleoside-diphosphate reductase large subunit; RRM1; RR1	Human	Sf9 insect cells
	RRM1 Protein, crucial for DNA synthesis, catalyzes the biosynthesis of deoxyribonucleotides from ribonucleotide precursors. Its enzymatic activity is essential, providing building blocks for accurate and efficient DNA replication. RRM1 Protein, Human (sf9, His-GST) is the recombinant human-derived RRM1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P71737

	GDI2 Protein, Human (P.pastoris, His) GDI-2; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta; RABGDIB	Human	P. pastoris
	GDI2 protein inhibits the exchange of GDP to GTP in Rab proteins and regulates intracellular membrane transport. GDI2 Protein, Human (P.pastoris, His) is the recombinant human-derived GDI2 protein, expressed by P. pastoris , with N-His labeled tag.

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Species
Source
Tag
Accession
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Molecular Weight
Purity
Endotoxin Level
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Cat. No.	Product Name	Chemical Structure

HY-D0199S

*Adenosine 5′-diphosphate-15N5 disodium*
Adenosine- ¹⁵N₅ 5′-diphosphate (disodium salt) is the ¹⁵N labeled Adenosine 5'-diphosphate disodium salt .

HY-W010918S2

Adenosine 5'-diphosphate-15N5 dilithium

Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-113400S3

*Cytidine diphosphate-d13 dilithium*
Cytidine diphosphate-d₁₃ dilithium is deuterium labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113359AS

*Uridine 5'-diphosphate-d12 dilithium*
Uridine 5'-diphosphate-d₁₂ dilithium is the deuterium labeled Uridine 5'-diphosphate .

HY-12651S

Primaquine-d3 diphosphate
Primaquine-d₃ (diphosphate) is the deuterium labeled Primaquine diphosphate. Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale .

HY-113400S

*Cytidine diphosphate-15N3 dilithium*
Cytidine diphosphate- ¹⁵N₃ dilithium is ¹⁵N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-W010918S3

Adenosine 5'-diphosphate-13C5

Adenosine 5'-diphosphate- ¹³C₅ (Adenosine diphosphate- ¹³C₅) is the ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

HY-113359AS3

*Uridine 5'-diphosphate-15N2 dilithium*
Uridine 5'-diphosphate- ¹⁵N₂ dilithium is ¹⁵N labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-113400S1

*Cytidine diphosphate-13C9 dilithium*
Cytidine diphosphate- ¹³C₉ dilithium is ¹³C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113359AS1

*Uridine 5'-diphosphate-13C9 dilithium*
Uridine 5'-diphosphate- ¹³C₉ dilithium is ¹³C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-113359AS2

*Uridine 5'-diphosphate-13C9,15N2 dilithium*
Uridine 5'-diphosphate- ¹³C₉, ¹⁵N₂ dilithium is ¹³C and ¹⁵N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y₆ receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-113066S2

Guanosine 5'-diphosphate-d13 dilithium

Guanosine 5'-diphosphate-d₁₃ (GDP-d₁₃) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113400S2

*Cytidine diphosphate-13C9,15N3 dilithium*
Cytidine diphosphate- ¹³C₉, ¹⁵N₃ dilithium is ¹³C and ¹⁵N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-113066S1

Guanosine 5'-diphosphate-13C10 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066S

Guanosine 5'-diphosphate-15N5 dilithium

Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113037S1

Farnesyl pyrophosphate-d3
Farnesyl pyrophosphate-d₃ (Farnesyl diphosphate-d₃) is deuterium-labeled Farnesyl pyrophosphate (HY-113037) .

HY-113066S3

Guanosine 5'-diphosphate-13C10,15N5 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀, ¹⁵N₅ (GDP- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113037AS

Farnesyl pyrophosphate-d6
Farnesyl pyrophosphate-d₆ (Farnesyl diphosphate-d₆) is a deuterium labeled Farnesyl pyrophosphate (HY-113037B). Farnesyl pyrophosphate is a key isoprenoid metabolite in the mevalonic acid (MVA) metabolic pathway. Farnesyl pyrophosphate is essential for proper localization and activation of proteins .

HY-17589S

Chloroquine-d5 diphosphate

Chloroquine-d₅ (diphosphate) is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

HY-125954S

Uridine diphosphate glucuronic acid-13C,15N2

Uridine diphosphate glucuronic acid- ¹³C, ¹⁵N₂ (UDP-α-D-glucuronic acid- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled Uridine diphosphate glucuronic acid (HY-125954). Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .

HY-B0739AS

Citicoline-d9 sodium

Citicoline-d₉ (Cytidine diphosphate-choline-d₉) sodium is the deuterium labeled Citicoline sodium (HY-B0739A). Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study .

HY-B0445S1

NAD+-13C5
NAD+- ¹³C₅-1 is the ¹³C labeled NAD+ . NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-W654288

NAD+-d4
NAD+-d₄ is the deuterium-labeled NAD+ (HY-B0445). NAD+-d₄ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-11101S

Alendronate-d6 sodium hydrate
Alendronate-d₆ sodium hydrate is deuterated labeled Alendronate sodium hydrate (HY-11101). Alendronate sodium hydrate is a farnesyl diphosphate synthase inhibitor with IC₅₀ of 460 nM.

HY-B0153AS

Ticlopidine-d4 hydrochloride
Ticlopidine-d₄ (hydrochloride) is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.

HY-15592AS

Cabotegravir-d3 sodium
Cabotegravir-d₃ (sodium) is the deuterium labeled Cabotegravir sodium. Cabotegravir sodium is a highly potent HIV integrase inhibitor with an IC50 value of 2.5 nM for HIVADA. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltr

HY-135811S1

Desethyl chloroquine-d5
Desethyl chloroquine-d₅ is deuterium labeled Desethyl chloroquine. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .

HY-135811S

Desethyl chloroquine-d4
Desethyl chloroquine-d₄ is the deuterium labeled Desethyl chloroquine. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .

HY-B0631S

Alendronic acid-d6
Alendronic acid-d₆ is the deuterium labeled Alendronic acid. Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease .

HY-B0341S

Nicorandil-d4
Nicorandil-d₄ (SG-75-d₄) is the deuterium labeled Nicorandil. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases .

HY-B1826S2

Adefovir-d4
Adefovir-d₄ is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC₅₀ of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .

HY-107867S1

(Rac)-Clopidogrel hydrogen-d9 sulfate

(Rac)-Clopidogrel hydrogen-d₉ sulfate is the deuterium labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .

HY-107867S2

Clopidogrel-13C,d3 sulfate

Clopidogrel- ¹³C,d₃ sulfate is the deuterium and ¹³C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83223

	NME2 Antibody (YA2968) NME2; NM23B; Nucleoside diphosphate kinase B; NDK B; NDP kinase B; C-myc purine-binding transcription factor PUF; Histidine protein kinase NDKB; nm23-H2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	NME2 Antibody (YA2968) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2968), targeting NME2, with a predicted molecular weight of 17 kDa (observed band size: 17 kDa). NME2 Antibody (YA2968) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82976

	DPS1 Antibody (YA2721) Trans-prenyltransferase 1; TPT 1; Solanesyl-diphosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1	WB, IP	Human
	DPS1 Antibody (YA2721) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2721), targeting DPS1, with a predicted molecular weight of 46 kDa (observed band size: 46 kDa). DPS1 Antibody (YA2721) can be used for WB, IP experiment in human background.

HY-P86994

	NUDT5 Antibody (YA6687) ADP sugar pyrophosphatase antibody; ADP-sugar pyrophosphatase antibody; hYSAH 1 antibody; hYSAH1 antibody; Nucleoside diphosphate linked moiety X motif 5 antibody; Nucleoside diphosphate linked moiety X type motif 5 antibody; Nucleoside diphosphate-linked moiety X motif 5 antibody; Nudix (nucleoside diphosphate linked moiety X) type motif 5 antibody; Nudix motif 5 antibody; Nudix type motif 5 antibody; ADP sugar pyrophosphatase antibody; ADP-sugar pyrophosphatase antibody; hYSAH 1 antibody; hYSAH1 antibody; Nucleoside diphosphate linked moiety X motif 5 antibody; Nucleoside diphosphate linked moiety X type motif 5 antibody; Nucleoside diphosphate-linked moiety X motif 5 antibody; Nudix (nucleoside diphosphate linked moiety X) type motif 5 antibody; Nudix motif 5 antibody; Nudix type motif 5 antibody; NUDT 5 antibody; Nudt5 antibody; NUDT5_HUMAN antibody; YSA1 antibody; YSA1H antibody	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P81705

	NUDT19 Antibody (YA1450) nudix (nucleoside diphosphate linked moiety X)-type motif 19; RP2	WB, IHC-F, IHC-P, ICC/IF	Human, Rat
	NUDT19 Antibody (YA1450) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1450), targeting NUDT19, with a predicted molecular weight of 42 kDa (observed band size: 42 kDa). NUDT19 Antibody (YA1450) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, rat background.

HY-P81289

	NM23A Antibody (YA1002) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB	Human, Mouse, Rat
	NM23A Antibody (YA1002) is a non-conjugated IgG1 antibody, targeting NM23A, with a predicted molecular weight of 17 kDa (observed band size: 16,18 kDa). NM23A Antibody (YA1002) can be used for WB experiment in human, mouse, rat background.

HY-P81289A

	NM23A Antibody (YA1003) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB	Human
	NM23A Antibody (YA1003) is a non-conjugated IgG antibody, targeting NM23A, with a predicted molecular weight of 17 kDa (observed band size: 17 kDa). NM23A Antibody (YA1003) can be used for WB experiment in human background.

HY-P85299

	NM23-H1 Antibody (YA4991) NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1	WB, IHC-P, ICC/IF, FC, ELISA	Human
	NM23-H1 Antibody (YA4991) is a mouse-derived and non-conjugated monoclonal antibody, targeting to NM23-H1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-163785

1"-α-Azido-RDPr		Azide
1"-α-Azido-RDPr (Compound 11) is an analog of adenosine diphosphate ribose, and exhibits inhibitory efficacy against the SARS-CoV-2 nonstructural protein macodomain SARS-CoV-2 NSP3 Mac1 with an IC₅₀ of 30 nM .

Cat. No.	Product Name		Classification

HY-W749117

*Inosine 5′-diphosphate* sodium**		Nucleotides and their Analogs I
Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .

HY-W010918

Adenosine 5'-diphosphate 3 Publications Verification Adenosine diphosphate; ADP		Nucleotides and their Analogs A
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-D0199

*Adenosine 5'-diphosphate* disodium** 3 Publications Verification		Nucleotides and their Analogs A
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-D0882

*Adenosine 5'-diphosphate* dicyclohexylammonium**		Nucleotides and their Analogs A
Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate dicyclohexylammonium induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors .

HY-W010791

*Adenosine 5'-diphosphate* sodium salt** 3 Publications Verification		Nucleotides and their Analogs A
Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors .

HY-137243

*Adenosine 3',5'-diphosphate* disodium**		Nucleotides and their Analogs A
Adenosine 3',5'-diphosphate disodium is an hydroxysteroid sulfotransferases inhibitor .

HY-113066A

*Guanosine 5'-diphosphate* disodium salt** 2 Publications Verification GDP disodium salt		Nucleotides and their Analogs
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate		Nucleotides and their Analogs
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W008940

*Cytidine 5'-diphosphate* disodium salt** Cytidine diphosphate disodium		Nucleotides and their Analogs C
Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-113066

Guanosine 5'-diphosphate GDP		Nucleotides and their Analogs
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-W008915

*Cytidine 5'-diphosphate* trisodium salt** CDP		Nucleotides and their Analogs
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .

HY-W010861

*2'-Deoxycytidine-5'-diphosphate* trisodium** 1 Publications Verification dCDP trisodium		Nucleotides and their Analogs C
2'-Deoxycytidine-5'-diphosphate (dCDP) trisodium is an endogenous metabolite.

HY-172507

3'-O-Methylguanosine-5'-diphosphate		Nucleotides and their Analogs G
3'-O-Methylguanosine-5'-diphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-138227

3′-Deoxyadenosine 5′-diphosphate 3′-dADP		Nucleotides and their Analogs A
3′-Deoxyadenosine 5′-diphosphate (3′-dADP)It can be used to study various physiological processes such as energy metabolism and information transmission.

HY-154828

Uridine 3′,5′-diphosphate 3′,5′-UDP		Nucleotides and their Analogs U
Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) is a competitive RNase inhibitor .

HY-138227A

*3′-Deoxyadenosine 5′-diphosphate* disodium** 3′-dADP disodium		Nucleotides and their Analogs A
3′-Deoxyadenosine 5′-diphosphate (3′-dADP) disodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.

HY-164112

*1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium* 18:1 CDP DG		Nucleotides and their Analogs C
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate .

HY-W010854

*2'-Deoxyadenosine 5'-di-phos-phate* disodium** dADP disodium		Nucleotides and their Analogs A
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

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