NAD+ (GMP Like) (Synonyms: β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like))

Name: NAD+ (GMP Like)
Brand: MedChemExpress
SKU: HY-B0445GL
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0445GL Purity: 99.79%: Data Sheet
COA

SDS
Handling Instructions
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NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

For research use only. We do not sell to patients.

NAD+ (GMP Like) Chemical Structure

CAS No. : 53-84-9

Size	Stock	Quantity
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Description

In Vitro

NAD+ (GMP Like) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ (GMP Like) is the oxidized form of NADH^[1]. NAD+ (GMP Like) is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Oral NAD+ (GMP Like) supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

663.43

Formula

C₂₁H₂₇N₇O₁₄P₂

CAS No.

53-84-9

Appearance

Powder

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]2O)N3C=NC4=C3N=CN=C4N)[C@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC(C(N)=O)=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O : 11.67 mg/mL (17.59 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5073 mL	7.5366 mL	15.0732 mL
5 mM	0.3015 mL	1.5073 mL	3.0146 mL
10 mM	0.1507 mL	0.7537 mL	1.5073 mL

View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.79%

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Data Sheet (272 KB) SDS (252 KB)

COA (251 KB) HNMR (310 KB) RP-HPLC (205 KB) MS (104 KB)

Handling Instructions (2659 KB)

References

[1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70. [Content Brief]

[2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92. [Content Brief]

[3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.5073 mL	7.5366 mL	15.0732 mL	37.6830 mL
	5 mM	0.3015 mL	1.5073 mL	3.0146 mL	7.5366 mL
	10 mM	0.1507 mL	0.7537 mL	1.5073 mL	3.7683 mL
	15 mM	0.1005 mL	0.5024 mL	1.0049 mL	2.5122 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

NAD+ (GMP Like) Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NAD+ (GMP Like)53-84-9β-DPN (GMP Like)β-NAD (GMP Like)β-Nicotinamide Adenine Dinucleotide (GMP Like)Endogenous MetaboliteInhibitorinhibitorinhibit

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NAD+ (GMP Like) (Synonyms: β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like))

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NAD+ (GMP Like) Related Antibodies

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Biological Activity

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NAD+ (GMP Like) Related Antibodies

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Complete Stock Solution Preparation Table

NAD+ (GMP Like) Related Classifications

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