2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Hepcidin

Hepcidin

Hepcidin is a 25-amino-acid peptide hormone secreted by hepatocytes. Hepcidin determines plasma iron concentrations and total body iron content. The function of hepcidin is to control the activity of the cellular iron exporter ferroportin, which delivers iron to plasma from intestinal iron absorption and from iron stores.

Hepcidin Related Products (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113066
    Guanosine 5'-diphosphate
    		Inhibitor
    Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
    Guanosine 5'-diphosphate