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Results for "

retinoic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	RAR/RXR (73) Aldehyde Dehydrogenase (ALDH) (2) AP-1 (2) Apoptosis (17) Aryl Hydrocarbon Receptor (1) Autophagy (30) Bacterial (3) Bcl-2 Family (3) Biochemical Assay Reagents (2) Cytochrome P450 (10) Drug Derivative (4) Drug Metabolite (5) Endogenous Metabolite (21) FGFR (2) Fungal (2) HBV (1) HCV (2) HSP (3) IFNAR (2) Interleukin Related (3) Isotope-Labeled Compounds (20) Ligands for Target Protein for PROTAC (1) LXR (1) mGluR (1) Nuclear Hormone Receptor 4A/NR4A (1) Organoid (1) PKD (3) PPAR (8) PROTACs (3) Reactive Oxygen Species (ROS) (2) Reference Standards (13) ROR (18) SNIPERs (3) SphK (2) Steroid Sulfatase (1) Toll-like Receptor (TLR) (6) VD/VDR (1)
By Research Areas:	Cancer (83) Endocrinology (2) Infection (9) Inflammation/Immunology (54) Metabolic Disease (16) Neurological Disease (7)

By Targets:

RAR/RXR (73)

Aldehyde Dehydrogenase (ALDH) (2)

AP-1 (2)

Apoptosis (17)

Aryl Hydrocarbon Receptor (1)

Autophagy (30)

Bacterial (3)

Bcl-2 Family (3)

Biochemical Assay Reagents (2)

Cytochrome P450 (10)

Drug Derivative (4)

Drug Metabolite (5)

Endogenous Metabolite (21)

FGFR (2)

Fungal (2)

HBV (1)

HCV (2)

HSP (3)

IFNAR (2)

Interleukin Related (3)

Isotope-Labeled Compounds (20)

Ligands for Target Protein for PROTAC (1)

LXR (1)

mGluR (1)

Nuclear Hormone Receptor 4A/NR4A (1)

Organoid (1)

PKD (3)

PPAR (8)

PROTACs (3)

Reactive Oxygen Species (ROS) (2)

Reference Standards (13)

ROR (18)

SNIPERs (3)

SphK (2)

Steroid Sulfatase (1)

Toll-like Receptor (TLR) (6)

VD/VDR (1)

By Research Areas:

Cancer (83)

Endocrinology (2)

Infection (9)

Inflammation/Immunology (54)

Metabolic Disease (16)

Neurological Disease (7)

141

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: RAR/RXR Amino acid Transporter Amino Acid Derivatives Amino Acid Decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Amino Acid Oxidase Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14649

Retinoic acid Maximum Cited Publications 90 Publications Verification Vitamin A acid; all-trans-retinoic acid; ATRA	Organoid RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

HY-14649R

Retinoic acid (Standard) Maximum Cited Publications 90 Publications Verification Vitamin A acid (Standard); all-trans-retinoic acid (Standard); ATRA (Standard)	Reference Standards RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
Retinoic acid (Standard) is the analytical standard of Retinoic acid. This product is intended for research and analytical applications. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

HY-14649G

Retinoic acid Vitamin A acid; all-trans-retinoic acid; ATRA	RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .

HY-141778S

Retinoic acid ethyl ester-d5	Isotope-Labeled Compounds Others	Others
Retinoic acid ethyl ester-d5 is the deuterium labeled Retinoic acid ethyl ester .

HY-14649S4

Retinoic acid-d5 Vitamin A acid-d₅; all-trans-retinoic acid-d₅; ATRA-d₅	Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
Retinoic acid-d₅ is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S3

Retinoic acid-d6 Vitamin A acid-d₆; all-trans-retinoic acid-d₆; ATRA-d₆	Isotope-Labeled Compounds RAR/RXR PPAR Autophagy Endogenous Metabolite	Cancer
Retinoic acid-d₆ is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].

HY-107395

BMS 753	RAR/RXR	Inflammation/Immunology
BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a K_i of 2 nM .

HY-14649S5

Retinoic acid-d3 Vitamin A acid-d₃; all-trans-retinoic acid-d₃; ATRA-d₃	Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
Retinoic acid-d₃ is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S6

Retinoic acid-d3-1 Vitamin A acid-d₃-1; all-trans-retinoic acid-d₃-1; ATRA-d₃-1	Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy	Metabolic Disease Cancer
Retinoic acid-d₃-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S2

*11-cis-Retinoic* Acid-d5**	Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
11-cis-Retinoic Acid-d₅ is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2].

HY-132334S

*9-cis-Retinoic* acid-d5**	Isotope-Labeled Compounds RAR/RXR Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
9-cis-Retinoic acid-d₅ is the deuterium labeled 9-cis-Retinoic acid. 9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities .

HY-15128R

*9-cis-Retinoic* acid (Standard)** Alitretinoin (Standard)	Reference Standards RAR/RXR Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
9-cis-Retinoic acid (Standard) is the analytical standard of 9-cis-Retinoic acid. This product is intended for research and analytical applications. 9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities[1][2][3][4][5].

HY-101556

Namirotene CBS-211A	Drug Derivative	Cancer
Namirotene (CBS-211A) is a retinoic acid analog, which is utilized in topical eye administration. Namirotene enhances 1α,25-dihydroxyvitamin D3-induced cytotoxicity in cell U937 and induces the differentation in U937 .

HY-W741560

*4,4-Dimethyl retinoic* acid**	Biochemical Assay Reagents
4,4-Dimethyl retinoic acid is a kind of biochemical reagent.

HY-15128

*9-cis-Retinoic* acid** 2 Publications Verification Alitretinoin	RAR/RXR Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities .

HY-W741375

*13-cis Retinoic* Acid Methyl Ester-d5**	Isotope-Labeled Compounds	Others
13-cis Retinoic Acid Methyl Ester-d₅ is the deuterium labeled 13-cis Retinoic Acid Methyl Ester (HY-W739914).

HY-101106

AR7 5+ Cited Publications	RAR/RXR	Neurological Disease Cancer
AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy .

HY-122299

Motretinide Ro 11-1430	Drug Derivative	Others
Motretinide (Ro 11-1430) is an aromatic retinoic acid with teratogenic activity. Motretinide can be used in studies on medication guidance during pregnancy .

HY-119359

*5,6-Epoxy-13-cis retinoic* acid** Isotretinoin EP impurity G	Drug Metabolite	Others
5,6-Epoxy-13-cis retinoic acid (Isotretinoin EP impurity G) is a metabolite of 13-cis retinoic acid .

HY-15127

Isotretinoin 5+ Cited Publications 13-cis-retinoic acid	RAR/RXR Endogenous Metabolite Autophagy	Cancer
Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-W587468

*all-trans-3,4-Didehydro retinoic* acid** 3,4-DHRA	Biochemical Assay Reagents
All-trans-3,4-Didehydro retinoic acid (3,4-DHRA) is a compound with gene-regulating activity that binds to retinoic acid receptors (RARs) and triggers receptor activation. All-trans-3,4-Didehydro retinoic acid plays an important role in skin development and differentiation and has potential anti-tumor and anti-inflammatory properties. All-trans-3,4-Didehydro retinoic acid is also being studied for the inhibition of a variety of diseases, including skin diseases and certain types of cancer.

HY-W364575

Methyl-4-oxoretinoate	Drug Derivative	Cancer
Methyl-4-oxoretinoate is a derivative of Retinoic acid (HY-14649). Methyl-4-oxoretinoate inhibits TPA (HY-18739)-induced ornithine decarboxylase (ODC) activity, and carcinogen-induced papillomas in mouse skin .

HY-108529

BMS493 5+ Cited Publications	RAR/RXR	Metabolic Disease
BMS493 is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 increases nuclear corepressor interaction with RARs. BMS493 also could prevent retinoic acid-induced differentiation . BMS493 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101108

Tazarotenic acid 1 Publications Verification AGN 190299	Drug Metabolite	Others
Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma .

HY-108520

HX630	RAR/RXR Apoptosis	Cancer
HX630 is a potent retinoic acid X receptor (RXR) agonist, can induce apoptosis, has anti-tumor effect, and can be used in Cushing's disease research .

HY-108531

ER 50891	RAR/RXR	Cancer
ER-50891 is a potent antagonist of retinoic acid receptor α(RARα). ER-50891 significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis .

HY-108531A

ER 50891 quarterhydrate	RAR/RXR	Cancer
ER 50891 quarterhydrate is a potent antagonist of retinoic acid receptor α(RARα). ER 50891 quarterhydrate significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis .

HY-15682G

TTNPB Ro 13-7410; Arotinoid acid; AGN191183	RAR/RXR	Cancer
TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist .

HY-107494A

all-trans-4-Oxoretinoic acid all-trans 4-Keto retinoic acid	Endogenous Metabolite	Metabolic Disease
all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).

HY-15127R

Isotretinoin (Standard) 13-cis-retinoic acid (Standard)	Reference Standards RAR/RXR Endogenous Metabolite Autophagy	Cancer
Isotretinoin (Standard) is the analytical standard of Isotretinoin. This product is intended for research and analytical applications. Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-156280

RARα antagonist 1	RAR/RXR	Endocrinology
RARα antagonist 1 (compound 21) is an orally active and selective retinoic acid receptor α(RARα) antagonist, with the IC₅₀ of 4.6nM .

HY-116248

Ro 41-5253 1 Publications Verification	RAR/RXR Apoptosis	Cancer
Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RARα) antagonist. Ro 41-5253 can bind RARα without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, has antitumor activity .

HY-107494

13-cis-4-Oxoretinoic acid 4-Keto 13-cis-retinoic acid; 4-Oxoisotretinoin; Ro 22-6595	Endogenous Metabolite	Others
13-cis-4-Oxoretinoic acid (4-Keto 13-cis-retinoic acid) is a metabolite of vitamin A in human plasma .

HY-15870

SR 11302 15+ Cited Publications	AP-1	Inflammation/Immunology Cancer
SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) .

HY-W744249

Isotretinoin-d5-1 13-cis-retinoic acid-d₅	Isotope-Labeled Compounds	Others
Isotretinoin-d5-1 (13-cis-Retinoic acid-d5) is the deuterium labeled Isotretinoin-d5-1 (HY-W744249) .

HY-107494AR

all-trans-4-Oxoretinoic acid (Standard) all-trans 4-Keto retinoic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
all-trans-4-Oxoretinoic acid (Standard) is the analytical standard of all-trans-4-Oxoretinoic acid. This product is intended for research and analytical applications. all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).

HY-119366

S18-000003	ROR	Inflammation/Immunology
S18-000003 is a potent, selective and orally active inhibitor of retinoic acid receptor-related orphan receptor-gamma-t (RORγt), with an IC₅₀ of <30 nM towards human RORγt in competitive binding assays. S18-000003 shows selectivity for RORγt over other ROR family members (IC₅₀>10 μM). S18-000003 can be used for the research of psoriasis with low risk of thymic aberrations .

HY-133552

RORγt Inverse agonist 10	ROR	Inflammation/Immunology
RORγt Inverse agonist 10 is a potent and orally bioavailable *RORγt (retinoic* acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC₅₀** of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R

HY-174987

mGluR1 activator-1	mGluR Steroid Sulfatase	Neurological Disease
mGluR1 activator-1 is a stable Vitamin K (HY-B2172) analogue and a mGluR1 activator that can penetrate the blood-brain barrier. mGluR1 activator-1 exhibits strong transcriptional activation via steroid and xenobiotic receptor as well as retinoic acid receptor. mGluR1 activator-1 induces neuronal differentiation in mouse neural progenitor cells. mGluR1 activator-1 can be used for the study of neurodegenerative disease such as Alzheimer’s .

HY-107494S3

13-cis-4-Oxoretinoic acid-d6 4-Keto 13-cis-retinoic acid-d₆; 4-Oxoisotretinoin-d₆; Ro 22-6595-d₆	Isotope-Labeled Compounds Endogenous Metabolite	Others
13-cis-4-Oxoretinoic acid-d₆ (4-Keto 13-cis-retinoic acid-d₆; 4-Oxoisotretinoin-d₆; Ro 22-6595-d₆) is the deuterium labeled 13-cis-4-Oxoretinoic acid (HY-107494). 13-cis-4-Oxoretinoic acid (4-Keto 13-cis-retinoic acid) is a metabolite of vitamin A in human plasma .

HY-105689

AGN 192870	RAR/RXR	Others
AGN 192870 is a RAR neutral antagonist with K_ds of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC₅₀s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism . AGN 192870 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-108522

PA452 1 Publications Verification	RAR/RXR	Metabolic Disease
PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development .

HY-106019A

Liarozole hydrochloride R75251 hydrochloride	Cytochrome P450 RAR/RXR	Metabolic Disease Inflammation/Immunology Cancer
Liarozole hydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole hydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of retinoic acid (IC₅₀=7 μM), resulting in increased tissue levels of retinoic acid. Liarozole hydrochloride shows antitumoral properties .

HY-106019B

Liarozole fumarate R75251 fumarate	Cytochrome P450	Metabolic Disease
Liarozole fumarate, an imidazole derivative, is a potent inhibitor of cytochrome P450-dependent all-trans retinoic acid 4-hydroxylase and acts by increasing the levels of all-trans retinoic acid in plasma and skin.

HY-106019

Liarozole R75251	Cytochrome P450 RAR/RXR	Metabolic Disease Inflammation/Immunology Cancer
Liarozole (R75251; R85246) is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of retinoic acid (IC₅₀=7 μM), resulting in increased tissue levels of retinoic acid. Liarozole shows antitumoral properties .

HY-112077

(Z)-Viaminate	Drug Derivative	Inflammation/Immunology
(Z)-Viaminate is a derivative of Retinoic acid (HY-14649).

HY-14799

Palovarotene 10+ Cited Publications R 667; Ro 3300074	RAR/RXR Autophagy	Others
Palovarotene is a nuclear retinoic acid receptor γ (RAR-γ) agonist.

HY-100532

CD437 3 Publications Verification AHPN	RAR/RXR Autophagy	Cancer
CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.

HY-106019R

Liarozole (Standard) R75251 (Standard)	Reference Standards Cytochrome P450 RAR/RXR	Metabolic Disease Inflammation/Immunology Cancer
Liarozole (Standard) is the analytical standard of Liarozole. This product is intended for research and analytical applications. Liarozole (R75251; R85246) is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of retinoic acid (IC50=7 μM), resulting in increased tissue levels of retinoic acid. Liarozole shows antitumoral properties .

HY-101108R

Tazarotenic acid (Standard) AGN 190299 (Standard)	Reference Standards Drug Metabolite	Others
Deoxycholic acid (Standard) is the analytical standard of Deoxycholic acid. This product is intended for research and analytical applications. Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5 .

Cat. No.	Product Name

HY-L038

Differentiation Inducing Compound Library

1,977 compounds

Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method.

MCE Differentiation Inducing Compound Library contains a unique collection of 1,977 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

Cat. No.	Product Name	Type

HY-14649G

Retinoic acid (GMP) Vitamin A acid (GMP); all-trans-retinoic acid (GMP); ATRA (GMP)	Fluorescent Dye
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .

HY-U00449G

AGN 193109 (GMP)

Fluorescent Dye

AGN 193109 (GMP) is AGN 193109 (HY-U00449) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AGN 193109 is a specific and highly effective retinoic acid receptor (RAR) antagonist . AGN 193109 (GMP) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity.

HY-107202GL

Polyinosinic-polycytidylic acid (GMP Like)

Poly(I:C) (GMP Like)

Fluorescent Dye

Polyinosinic-polycytidylic acid (Poly(I:C)) (GMP Like) is the GMP Like class Polyinosinic-polycytidylic acid (HY-107202), and can be used as pharmaceutical excipients. Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis .

HY-15682G

TTNPB (GMP) Ro 13-7410 (GMP); Arotinoid acid (GMP); AGN191183 (GMP)	Fluorescent Dye
TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist .

Cat. No.	Product Name	Type

HY-14649G

Retinoic acid (GMP) Vitamin A acid (GMP); all-trans-retinoic acid (GMP); ATRA (GMP)	Biochemical Assay Reagents
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .

HY-U00449G

AGN 193109 (GMP)

Biochemical Assay Reagents

HY-107202GL

Polyinosinic-polycytidylic acid (GMP Like)

Poly(I:C) (GMP Like)

Biochemical Assay Reagents

HY-W741560

*4,4-Dimethyl retinoic* acid**	Cell Assay Reagents
4,4-Dimethyl retinoic acid is a kind of biochemical reagent.

HY-W587468

all-trans-3,4-Didehydro retinoic acid

3,4-DHRA

Cell Assay Reagents

All-trans-3,4-Didehydro retinoic acid (3,4-DHRA) is a compound with gene-regulating activity that binds to retinoic acid receptors (RARs) and triggers receptor activation. All-trans-3,4-Didehydro retinoic acid plays an important role in skin development and differentiation and has potential anti-tumor and anti-inflammatory properties. All-trans-3,4-Didehydro retinoic acid is also being studied for the inhibition of a variety of diseases, including skin diseases and certain types of cancer.

HY-15682G

TTNPB (GMP) Ro 13-7410 (GMP); Arotinoid acid (GMP); AGN191183 (GMP)	Biochemical Assay Reagents
TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist .

Cat. No.	Product Name	Target	Research Area

HY-P3695

VSPPLTLGQLLS	FGFR	Cancer
VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation. VSPPLTLGQLLS inhibits 9-cisRA-induced tracheal lymphangiogenesis and blocks lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P3695A

VSPPLTLGQLLS TFA	FGFR	Cancer
VSPPLTLGQLLS TFA is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation. VSPPLTLGQLLS TFA inhibits 9-cisRA-induced tracheal lymphangiogenesis and blocks lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation .

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-14649

Retinoic acid Maximum Cited Publications 90 Publications Verification Vitamin A acid; all-trans-retinoic acid; ATRA	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Whitening Agent Cosmetic Research Endogenous metabolite Disease Research Fields Cancer	Organoid RAR/RXR PPAR Endogenous Metabolite Autophagy
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

HY-14649R

Retinoic acid (Standard) Maximum Cited Publications 90 Publications Verification Vitamin A acid (Standard); all-trans-retinoic acid (Standard); ATRA (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Reference Standards RAR/RXR PPAR Endogenous Metabolite Autophagy
Retinoic acid (Standard) is the analytical standard of Retinoic acid. This product is intended for research and analytical applications. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

HY-15128

*9-cis-Retinoic* acid** 2 Publications Verification Alitretinoin	Structural Classification Classification of Application Fields Terpenoids Source classification Diterpenoids Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	RAR/RXR Apoptosis Endogenous Metabolite
9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities .

HY-15127

Isotretinoin 5+ Cited Publications 13-cis-retinoic acid	Structural Classification Classification of Application Fields Terpenoids Source classification Diterpenoids Endogenous metabolite Disease Research Fields Cancer	RAR/RXR Endogenous Metabolite Autophagy
Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-107494A

all-trans-4-Oxoretinoic acid all-trans 4-Keto retinoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).

HY-P1934A

Cyclo(L-Phe-L-Pro)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-15128R

*9-cis-Retinoic* acid (Standard)** Alitretinoin (Standard)	Structural Classification Terpenoids Source classification Diterpenoids Endogenous metabolite	Reference Standards RAR/RXR Apoptosis Endogenous Metabolite
9-cis-Retinoic acid (Standard) is the analytical standard of 9-cis-Retinoic acid. This product is intended for research and analytical applications. 9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities[1][2][3][4][5].

HY-15127R

Isotretinoin (Standard) 13-cis-retinoic acid (Standard)	Structural Classification Terpenoids Source classification Diterpenoids Endogenous metabolite	Reference Standards RAR/RXR Endogenous Metabolite Autophagy
Isotretinoin (Standard) is the analytical standard of Isotretinoin. This product is intended for research and analytical applications. Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-107494AR

all-trans-4-Oxoretinoic acid (Standard) all-trans 4-Keto retinoic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
all-trans-4-Oxoretinoic acid (Standard) is the analytical standard of all-trans-4-Oxoretinoic acid. This product is intended for research and analytical applications. all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

Species:	Human (17) Mouse (5)
Tag:	His (14) SUMO (1) Tag Free (3) Myc (1) Fc (5)
Source:	HEK293 (11) E. coli (11)

Cat. No.	Compare	Product Name	Species	Source

HY-P71251A

	RBP7 Protein, Human (His) Retinoid-binding protein 7; Cellular retinoic acid-binding protein 4; CRABP4; CRBP4; Cellular retinoic acid-binding protein IV; CRABP-IV; RBP7	Human	E. coli
	RBP7 protein, a member of the CRBP family, is involved in the stability and metabolism of vitamin A. It binds to all-trans-retinol but with lower affinity compared to other CRBPs. RBP7 protein is expressed in fat, spleen, and other tissues, indicating possible tissue-specific functions. RBP7 Protein, Human (His) is the recombinant human-derived RBP7 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P79419

	Midkine Protein, Mouse Midkine; Mdk; MK; Retanoic acid-responsive protein; retinoic acid-induced differentiation factor	Mouse	E. coli
	Midkine (MDK) is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. It affects inflammatory responses, cell proliferation, adhesion, survival, tissue regeneration, differentiation and migration. Midkine Protein, Mouse is the recombinant mouse-derived Midkine protein, expressed by E. coli , with tag free.

HY-P75687

	CRABP1 Protein, Human Cellular retinoic acid-binding protein 1; CRABP-I; RBP5	Human	E. coli
	The CRABP1 protein is present in the cytoplasm and is involved in regulating the entry of retinoic acid into nuclear retinoic acid receptors. As an important molecular player, CRABP1 may mediate the complex process of interaction between retinoic acid and its nuclear receptor. CRABP1 Protein, Human is the recombinant human-derived CRABP1 protein, expressed by E. coli , with tag free.

HY-P75688

	CRABP2 Protein, Human (His) Cellular retinoic acid-binding protein 2; CRABP-II; CRABP2	Human	E. coli
	CRABP2 (cellular retinoic acid binding protein 2) plays a crucial role in cellular processes by transporting retinoic acid into the nucleus and mediating its contact with nuclear retinoic acid receptors. CRABP2 interacts with RXR (retinoic acid X receptor) and RARA (retinoic acid receptor Alpha) to regulate the retinoic acid signaling pathway. CRABP2 Protein, Human (His) is the recombinant human-derived CRABP2 protein, expressed by E. coli , with N-His labeled tag.

HY-P75689

	CRABP2 Protein, Mouse (His) Cellular retinoic acid-binding protein 2; CRABP-II; CRABP2	Mouse	E. coli
	CRABP2 is an important mediator that promotes intracellular retinoic acid transport and regulates its contact with nuclear retinoic acid receptors. This key role is essential for the cellular processes controlled by retinoic acid. CRABP2 Protein, Mouse (His) is the recombinant mouse-derived CRABP2 protein, expressed by E. coli , with N-His labeled tag.

HY-P75553

	Chemerin/RARRES2 Protein, Mouse (HEK293, Fc) 1 Publications Verification retinoic acid receptor responder protein 2; Chemerin; Rarres2	Mouse	HEK293
	Chemerin/RARRES2 proteins bind to signaling receptors and are involved in various processes, including promotion of adipocyte differentiation, protein phosphorylation, and insulin receptor signaling. It plays a role in brown adipocyte differentiation and is located in the extracellular region. Chemerin/RARRES2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Chemerin/RARRES2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75554

	Chemerin/RARRES2 Protein, Mouse (HEK293, His) 1 Publications Verification retinoic acid receptor responder protein 2; Chemerin; Rarres2	Mouse	HEK293
	Chemerin/RARRES2 proteins bind to signaling receptors and are involved in various processes, including promotion of adipocyte differentiation, protein phosphorylation, and insulin receptor signaling. It plays a role in brown adipocyte differentiation and is located in the extracellular region. Chemerin/RARRES2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Chemerin/RARRES2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700223AF

	Animal-Free Midkine Protein, Mouse (His) Midkine; Mdk; MK; Retanoic acid-responsive protein; retinoic acid-induced differentiation factor	Mouse	E. coli
	Midkine (MDK) is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors.It affects inflammatory responses, cell proliferation, adhesion, survival, tissue regeneration, differentiation and migration.Animal-Free Midkine Protein, Mouse (His) is the recombinant mouse-derived animal-FreeMidkine protein, expressed by E.coli , with C-His labeled tag.This product is for cell culture use only.

HY-P701402

	RXRB Protein, Human RXRB; retinoic acid receptor RXR-beta; Nuclear receptor subfamily 2 group B member 2; Retinoid X receptor beta	Human	E. coli
	RXRB protein is a receptor for retinoic acid and forms a heterodimer, especially RAR/RXR, which regulates gene expression through the retinoic acid response element (RARE). RXRB exhibits homodimerization and forms heterodimers with other retinoic acid receptor family members. RXRB Protein, Human is the recombinant human-derived RXRB protein, expressed by E. coli , with tag free.

HY-P701403

	RXRB Protein, Human (His) RXRB; retinoic acid receptor RXR-beta; Nuclear receptor subfamily 2 group B member 2; Retinoid X receptor beta	Human	E. coli
	RXRB protein is a receptor for retinoic acid and forms a heterodimer, especially RAR/RXR, which regulates gene expression through the retinoic acid response element (RARE). RXRB exhibits homodimerization and forms heterodimers with other retinoic acid receptor family members. RXRB Protein, Human (His) is the recombinant human-derived RXRB protein, expressed by E. coli , with N-6*His labeled tag.

HY-P76690

	ULBP4/RAET1E Protein, Human (HEK293, Fc) retinoic acid early transcript 1E; NKG2D ligand 4; LETAL; N2DL4	Human	HEK293
	ULBP4/RAET1E Protein crucially activates natural killer cell cytotoxicity by binding to and activating the KLRK1/NKG2D receptor. This interaction mediates cytotoxic responses, contributing to receptor activation and facilitating the recognition and targeting of marked cells for elimination. ULBP4/RAET1E's engagement with KLRK1/NKG2D underscores its significance in immune response regulation and natural killer cell activity modulation. ULBP4/RAET1E Protein, Human (HEK293, Fc) is the recombinant human-derived ULBP4/RAET1E protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76691

	ULBP4/RAET1E Protein, Human (HEK293, His) retinoic acid early transcript 1E; NKG2D ligand 4; LETAL; N2DL4	Human	HEK293
	ULBP4/RAET1E Protein crucially activates natural killer cell cytotoxicity by binding to and activating the KLRK1/NKG2D receptor. This interaction mediates cytotoxic responses, contributing to receptor activation and facilitating the recognition and targeting of marked cells for elimination. ULBP4/RAET1E's engagement with KLRK1/NKG2D underscores its significance in immune response regulation and natural killer cell activity modulation. ULBP4/RAET1E Protein, Human (HEK293, His) is the recombinant human-derived ULBP4/RAET1E protein, expressed by HEK293 , with C-His labeled tag.

HY-P77502

	ULBP-6/RAET1L Protein, Human (HEK293, Fc) UL16-binding protein 6; retinoic acid early transcript 1L protein; ULBP6; RAET1L	Human	HEK293
	ULBP-6/RAET1L Protein, a key immune response modulator, activates the KLRK1/NKG2D receptor, triggering natural killer (NK) cell cytotoxicity. This engagement is pivotal for the immune system's defense against threats, showcasing ULBP-6/RAET1L's orchestration of NK cell responses. Its specificity is highlighted by the absence of a binding association with beta2-microglobulin in molecular interactions. ULBP-6/RAET1L Protein, Human (HEK293, Fc) is the recombinant human-derived ULBP-6/RAET1L protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77503

	ULBP-6/RAET1L Protein, Human (HEK293, His) UL16-binding protein 6; retinoic acid early transcript 1L protein; ULBP6; RAET1L	Human	HEK293
	ULBP-6/RAET1L Protein, a key immune response modulator, activates the KLRK1/NKG2D receptor, triggering natural killer (NK) cell cytotoxicity. This engagement is pivotal for the immune system's defense against threats, showcasing ULBP-6/RAET1L's orchestration of NK cell responses. Its specificity is highlighted by the absence of a binding association with beta2-microglobulin in molecular interactions. ULBP-6/RAET1L Protein, Human (HEK293, His) is the recombinant human-derived ULBP-6/RAET1L protein, expressed by HEK293 , with C-His labeled tag.

HY-P72023

	ULBP1/RAET1I Protein, Human (HEK293, Fc-Myc) ALCAN-beta; NKG2D ligand 1; N2DL-1; NKG2DL1; retinoic acid early transcript 1I	Human	HEK293
	The ULBP1/RAET1I protein is critical in the cytotoxicity of natural killer cells and can bind to and activate the KLRK1/NKG2D receptor. This mechanism highlights the importance of ULBP1/RAET1I in mediating cytotoxic responses. ULBP1/RAET1I Protein, Human (HEK293, Fc-Myc) is the recombinant human-derived ULBP1/RAET1I protein, expressed by HEK293 , with C-hFc, C-Myc labeled tag.

HY-P70099

	Chemerin/RARRES2 Protein, Human (HEK293, His) 1 Publications Verification rHuretinoic acid receptor responder protein 2/Chemerin, His; retinoic acid receptor responder protein 2; Chemerin; RAR-responsive protein TIG2; Tazarotene-induced gene 2 protein; RARRES2; TIG2	Human	HEK293
	Chemerin/RARRES2 protein is an adipokine secreted by adipocytes that is activated by CMKLR1 and serves as a CMKLR2 ligand to complexly regulate adipogenesis, metabolism, and inflammation. It actively regulates adipocyte differentiation, affects lipid and glucose metabolism, and plays a role in angiogenesis. Chemerin/RARRES2 Protein, Human (HEK293, His) is the recombinant human-derived Chemerin/RARRES2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71163

	ULBP1/RAET1I Protein, Human (HEK293, His) NKG2D ligand 1; N2DL-1; NKG2DL1; ALCAN-beta; retinoic acid early transcript 1I; UL16-binding protein 1; ULBP1	Human	HEK293
	The ULBP1/RAET1I protein is critical in the cytotoxicity of natural killer cells and can bind to and activate the KLRK1/NKG2D receptor. This mechanism highlights the importance of ULBP1/RAET1I in mediating cytotoxic responses. ULBP1/RAET1I Protein, Human (HEK293, His) is the recombinant human-derived ULBP1/RAET1I protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71020

	UBE2L6 Protein, Human (His) Ubiquitin/ISG15-Conjugating Enzyme E2 L6; retinoic acid-Induced Gene B Protein; RIG-B; UbcH8; Ubiquitin Carrier Protein L6; Ubiquitin-Protein Ligase L6; UBE2L6; UBCH8	Human	E. coli
	The UBE2L6 protein plays a key role in cell regulation by catalyzing the covalent attachment of ubiquitin or ISG15 to other proteins. Notably, it plays a role in E6/E6-AP-induced ubiquitination of p53/TP53, a core process in regulating cellular responses to stress and DNA damage. UBE2L6 Protein, Human (His) is the recombinant human-derived UBE2L6 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P71164

	NKG2DL2 Protein, Human (HEK293, His) NKG2D Ligand 2; N2DL-2; NKG2DL2; ALCAN-Alpha; retinoic acid Early Transcript 1H; UL16-Binding Protein 2; ULBP2; N2DL2; RAET1H	Human	HEK293
	NKG2DL2 Protein activates KLRK1/NKG2D receptor, promoting natural killer cell cytotoxicity. Importantly, it does not bind beta2-microglobulin, confirmed by research findings. NKG2DL2 Protein, Human (HEK293, His) is the recombinant human-derived NKG2DL2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71539

	Lymphocyte antigen 6E/LY6E Protein, Human (His-SUMO) LY6E; 9804; RIGE; SCA2; TSA1; Lymphocyte antigen 6E; Ly-6E; retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1; TSA-1	Human	E. coli
	Lymphocyte antigen 6E/LY6E protein is a GPI-anchored cell surface regulator that regulates T cell receptor signaling through interaction with CD3Z/CD247. It limits the entry of human coronaviruses, serves as the primary receptor for syncytin-A, and may modulate nicotinic acetylcholine receptor activity. Lymphocyte antigen 6E/LY6E Protein, Human (His-SUMO) is the recombinant human-derived Lymphocyte antigen 6E/LY6E protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P705423

	Lymphocyte antigen 6E/LY6E Protein, Human (HEK293, Fc) LY6E; 9804; RIGE; SCA2; TSA1; Lymphocyte antigen 6E; Ly-6E; retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1; TSA-1	Human	HEK293

HY-P700138AF

	Animal-Free MDK Protein, Human (His) Amphiregulin associated protein; Amphiregulin-associated protein; ARAP; FLJ27379; Mdk; Midgestation and kidney protein; Midkine; MK 1; MK; MK_HUMAN; MK1; NEGF 2; NEGF2; Neurite growth promoting factor 2; Neurite outgrowth promoting protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; retinoic acid inducible factor	Human	E. coli
	Midkine (MDK) protein is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. MDK regulates inflammatory responses, cell proliferation, adhesion, growth, survival, tissue regeneration, differentiation, and migration and plays a crucial role in inflammation by recruiting neutrophils and macrophages. Animal-Free MDK Protein, Human (His) is the recombinant human-derived animal-FreeMDK protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

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Cat. No.	Product Name	Chemical Structure

HY-141778S

Retinoic acid ethyl ester-d5
Retinoic acid ethyl ester-d5 is the deuterium labeled Retinoic acid ethyl ester .

HY-14649S4

Retinoic acid-d5

Retinoic acid-d₅ is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S3

Retinoic acid-d6

Retinoic acid-d₆ is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].

HY-132334S

*9-cis-Retinoic* acid-d5**
9-cis-Retinoic acid-d₅ is the deuterium labeled 9-cis-Retinoic acid. 9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities .

HY-14649S5

Retinoic acid-d3

Retinoic acid-d₃ is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S6

Retinoic acid-d3-1

Retinoic acid-d₃-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S2

11-cis-Retinoic Acid-d5

11-cis-Retinoic Acid-d₅ is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2].

HY-W741375

*13-cis Retinoic* Acid Methyl Ester-d5**
13-cis Retinoic Acid Methyl Ester-d₅ is the deuterium labeled 13-cis Retinoic Acid Methyl Ester (HY-W739914).

HY-W744249

Isotretinoin-d5-1
Isotretinoin-d5-1 (13-cis-Retinoic acid-d5) is the deuterium labeled Isotretinoin-d5-1 (HY-W744249) .

HY-107494S3

13-cis-4-Oxoretinoic acid-d6
13-cis-4-Oxoretinoic acid-d₆ (4-Keto 13-cis-retinoic acid-d₆; 4-Oxoisotretinoin-d₆; Ro 22-6595-d₆) is the deuterium labeled 13-cis-4-Oxoretinoic acid (HY-107494). 13-cis-4-Oxoretinoic acid (4-Keto 13-cis-retinoic acid) is a metabolite of vitamin A in human plasma .

HY-100532S

CD437-13C6
CD437- ¹³C₆ is the ¹³C- and deuterium labeled CD437. CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.

HY-15388S

Tazarotene-d8
Tazarotene-d₈ is the deuterium labeled Tazarotene. Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris .

HY-101108S

Tazarotenic acid-d6
Tazarotenic acid-d₆ is deuterium labeled Tazarotenic acid. Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma .

HY-107494S2

4-Oxoretinoic acid-d3
4-Oxoretinoic acid-d₃ is the deuterium labeled 4-Oxoretinoic acid .

HY-U00449S

AGN 193109-d7
AGN 193109-d₇ is the deuterium labeled AGN 193109. AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs), with Kds of 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ, respectively.

HY-15388S3

Tazarotene-d6
Tazarotene-d₆ (AGN 190168-d₆) is deuterium labeled Tazarotene. Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-15388S2

Tazarotene-13C6
Tazarotene- ¹³C₆ (AGN 190168- ¹³C₆) is ¹³C labeled Tazarotene. Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W654334

9-cis-Retinol-d5
9-cis-Retinol-d₅ is deuterium labeled 9-cis Retinol. 9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells .

HY-101108S1

Tazarotenic acid-13C2,d2
Tazarotenic acid-13C2,d2 (AGN 190299-13C2,d2) is the ¹³C and deuterium labeled isotope of Tazarotenic acid (HY-101108). Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma .

HY-15388S1

Tazarotene-13C2,d2

Tazarotene-13C2,d2 (AGN 190168-13C2,d2) is the ¹³C and deuterium labeled isotope of Tazarotene (HY-15388). Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80308

	Retinoic Acid Receptor alpha Antibody (YA096) 1 Publications Verification	WB, FC	Human
	Retinoic Acid Receptor alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 51 kDa, targeting to Retinoic Acid Receptor alpha. It can be used for WB,FC assays with tag free, in the background of Human.

HY-P81829

	Retinoic Acid Receptor beta Antibody (YA1574) RARB; HAP; NR1B2; retinoic acid receptor beta; RAR-beta; HBV-activated protein; Nuclear receptor subfamily 1 group B member 2; RAR-epsilon	WB, IHC-P, ICC/IF	Human
	Retinoic Acid Receptor beta Antibody (YA1574) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1574), targeting Retinoic Acid Receptor beta, with a predicted molecular weight of 50 kDa (observed band size: 55 kDa). Retinoic Acid Receptor beta Antibody (YA1574) can be used for WB, IHC-P, ICC/IF experiment in human background.

HY-P81907

	CRABP2 Antibody (YA1652) Cellular retinoic acid-binding protein II; CRABP-II	WB, ICC/IF	Human
	CRABP2 Antibody (YA1652) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1652), targeting CRABP2, with a predicted molecular weight of 16 kDa (observed band size: 16 kDa). CRABP2 Antibody (YA1652) can be used for WB, ICC/IF experiment in human background.

HY-P82573

	DDX58 Antibody (YA2318) RIG-I-like receptor 1; RLR-1; RLR1; retinoic acid-inducible gene 1 protein; RIG-1; RIG1; RIG-I; RIGI	WB, IP	Human
	DDX58 Antibody (YA2318) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2318), targeting DDX58, with a predicted molecular weight of 107 kDa (observed band size: 107 kDa). DDX58 Antibody (YA2318) can be used for WB, IP experiment in human background.

HY-P82115

	Retinoic Acid Receptor gamma Antibody (YA1860) NR1B3; RAR gamma; RARC; Rarg	WB, ICC/IF	Human, Rat
	Retinoic Acid Receptor gamma Antibody (YA1860) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1860), targeting Retinoic Acid Receptor gamma, with a predicted molecular weight of 50 kDa (observed band size: 50 kDa). Retinoic Acid Receptor gamma Antibody (YA1860) can be used for WB, ICC/IF experiment in human, rat background.

HY-P87185

	Stra8 Antibody (YA6873) Stimulated by retinoic acid 8 antibody; STRA 8 antibody	WB, ICC/IF, FC	Human

HY-P87130

	ULBP1 Antibody (YA6823) Alcan beta antibody; ALCAN-beta antibody; N2DL-1 antibody; N2DL1 antibody; N2DL1_HUMAN antibody; NKG2D ligand 1 antibody; NKG2D ligand 1 precursor antibody; NKG2DL1 antibody; RAET1I antibody; retinoic acid early transcript 1I antibody; Alcan beta antibody; ALCAN-beta antibody; N2DL-1 antibody; N2DL1 antibody; N2DL1_HUMAN antibody; NKG2D ligand 1 antibody; NKG2D ligand 1 precursor antibody; NKG2DL1 antibody; RAET1I antibody; retinoic acid early transcript 1I antibody; UL16 antibody; UL16 binding protein 1 antibody; UL16-binding protein 1 antibody; ULBP1 antibody	WB	Human

HY-P83758

	ROR gamma T Antibody (YA3559) IMD42 antibody; MGC129539 antibody; NR1F3 antibody; Nuclear receptor ROR gamma antibody; Nuclear receptor subfamily 1 group F member 3 antibody; RAR related orphan receptor C antibody; retinoic acid binding receptor gamma antibody; Retinoid related orphan receptor gamma antibody; Rorc antibody; RORG antibody; RORG_HUMAN antibody; RZR GAMMA antibody; RZRG antibody; TOR antibody	WB, IHC-P	Human, Rat
	ROR gamma T Antibody (YA3559) is an unconjugated,, rabbit-derived, anti-ROR gamma T antibody. Cytokeratin 19 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, and predicted: rat, chicken, dog, pig, cow, horse, rabbit background without labeling.

HY-P87060

	Retinoid X Receptor beta/RXRB Antibody (YA6753) DAUD I6 antibody; DAUDI6 antibody; H 2RIIBP antibody; H2RIIBP antibody; MGC1831 antibody; MHC class I promoter binding protein antibody; NR2B2 antibody; Nuclear receptor subfamily 2 group B member 2 antibody; RCoR 1 antibody; RCoR1 antibody; DAUD I6 antibody; DAUDI6 antibody; H 2RIIBP antibody; H2RIIBP antibody; MGC1831 antibody; MHC class I promoter binding protein antibody; NR2B2 antibody; Nuclear receptor subfamily 2 group B member 2 antibody; RCoR 1 antibody; RCoR1 antibody; retinoic acid receptor RXR beta antibody; retinoic acid receptor RXR-beta antibody; Retinoid X receptor beta antibody; RXR beta antibody; Rxrb antibody; RXRB_HUMAN antibody; RXRbeta antibody	WB, ICC/IF, IHC-P	Human, Mouse, Rat

HY-P87131

	ULBP3 Antibody (YA6824) ALCAN- gamma antibody; ALCAN-gamma antibody; N2DL-3 antibody; N2DL3 antibody; N2DL3_HUMAN antibody; NKG2D ligand 3 antibody; NKG2D ligand 3 precursor antibody; NKG2DL3 antibody; OTTHUMP00000017411 antibody; RAET1N antibody; ALCAN- gamma antibody; ALCAN-gamma antibody; N2DL-3 antibody; N2DL3 antibody; N2DL3_HUMAN antibody; NKG2D ligand 3 antibody; NKG2D ligand 3 precursor antibody; NKG2DL3 antibody; OTTHUMP00000017411 antibody; RAET1N antibody; retinoic acid early transcript 1N antibody; UL16 binding protein 3 antibody; UL16-binding protein 3 antibody; ULBP3 antibody	WB, IHC-P, IP	Human

HY-P87071

	SHARP2 Antibody (YA6764) BHE40_HUMAN antibody; bHLHB2 antibody; bHLHe40 antibody; Class B Basic Helix Loop Helix Protein 2 antibody; Class B basic helix-loop-helix protein 2 antibody; Class E basic helix loop helix protein 40 antibody; Class E basic helix-loop-helix protein 40 antibody; Clast5 antibody; DEC1 antibody; Differentially expressed in chondrocytes protein 1 antibody; BHE40_HUMAN antibody; bHLHB2 antibody; bHLHe40 antibody; Class B Basic Helix Loop Helix Protein 2 antibody; Class B basic helix-loop-helix protein 2 antibody; Class E basic helix loop helix protein 40 antibody; Class E basic helix-loop-helix protein 40 antibody; Clast5 antibody; DEC1 antibody; Differentially expressed in chondrocytes protein 1 antibody; E47 interaction protein 1 antibody; EIP1 antibody; Enhancer of split and hairy related protein 2 antibody; Enhancer-of-split and hairy-related protein 2 antibody; SHARP 2 antibody; SHARP-2 antibody; Stimulated by retinoic acid gene 13 protein antibody; STRA13 antibody	WB, IHC-P, ICC/IF	Human

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