1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 13-cis-4-Oxoretinoic acid

13-cis-4-Oxoretinoic acid  (Synonyms: 4-Keto 13-cis-retinoic acid; 4-Oxoisotretinoin; Ro 22-6595)

Cat. No.: HY-107494 Purity: 95.41%
Handling Instructions Technical Support

13-cis-4-Oxoretinoic acid (4-Keto 13-cis-retinoic acid) is a metabolite of vitamin A in human plasma.

For research use only. We do not sell to patients.

13-cis-4-Oxoretinoic acid Chemical Structure

13-cis-4-Oxoretinoic acid Chemical Structure

CAS No. : 71748-58-8

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Other Forms of 13-cis-4-Oxoretinoic acid:

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Description

13-cis-4-Oxoretinoic acid (4-Keto 13-cis-retinoic acid) is a metabolite of vitamin A in human plasma[1].

Molecular Weight

314.42

Formula

C20H26O3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(/C=C/C=C(/C=C/C1=C(C(CCC(C)1C)=O)C)C)=C/C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (318.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1805 mL 15.9023 mL 31.8046 mL
5 mM 0.6361 mL 3.1805 mL 6.3609 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1805 mL 15.9023 mL 31.8046 mL 79.5115 mL
5 mM 0.6361 mL 3.1805 mL 6.3609 mL 15.9023 mL
10 mM 0.3180 mL 1.5902 mL 3.1805 mL 7.9511 mL
15 mM 0.2120 mL 1.0602 mL 2.1203 mL 5.3008 mL
20 mM 0.1590 mL 0.7951 mL 1.5902 mL 3.9756 mL
25 mM 0.1272 mL 0.6361 mL 1.2722 mL 3.1805 mL
30 mM 0.1060 mL 0.5301 mL 1.0602 mL 2.6504 mL
40 mM 0.0795 mL 0.3976 mL 0.7951 mL 1.9878 mL
50 mM 0.0636 mL 0.3180 mL 0.6361 mL 1.5902 mL
60 mM 0.0530 mL 0.2650 mL 0.5301 mL 1.3252 mL
80 mM 0.0398 mL 0.1988 mL 0.3976 mL 0.9939 mL
100 mM 0.0318 mL 0.1590 mL 0.3180 mL 0.7951 mL
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13-cis-4-Oxoretinoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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13-cis-4-Oxoretinoic acid
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