Liarozole dihydrochloride (Standard) (Synonyms: R75251 dihydrochloride (Standard))

Cat. No.: HY-106019CR Purity: ≥98%: FAQs
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Liarozole (dihydrochloride) (Standard) is the analytical standard of Liarozole (dihydrochloride). This product is intended for research and analytical applications. Liarozole (R75251) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole dihydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of RA (IC50=7 μM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties[1][2][3].

For research use only. We do not sell to patients.

Liarozole dihydrochloride (Standard) Chemical Structure

CAS No. : 1883548-96-6

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Description	Liarozole (dihydrochloride) (Standard) is the analytical standard of Liarozole (dihydrochloride). This product is intended for research and analytical applications. Liarozole (R75251) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole dihydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of RA (IC50=7 μM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties[1][2][3].
Molecular Weight	381.69
Formula	C₁₇H₁₅Cl₃N₄
CAS No.	1883548-96-6
SMILES	ClC1=CC(C(C2=CC=C3N=CNC3=C2)N4C=CN=C4)=CC=C1.[H]Cl.[H]Cl
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Liarozole dihydrochloride (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Liarozole dihydrochloride (Standard)1883548-96-6R75251 dihydrochloride (Standard)Cytochrome P450RAR/RXRCYPsRetinoic acid receptorsRetinoid X receptorsSCIDOvariectomizedMCF-7MesenchymalImidazoleHydroxylationInhibitorinhibitorinhibit

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Liarozole dihydrochloride (Standard) (Synonyms: R75251 dihydrochloride (Standard))

Product Information

Purity & Documentation

Customer Review

Liarozole dihydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator