Search Result

Pathways Recommended:	MAPK/ERK Pathway

Results for "

MAPK Kinase Kinase Kinase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MAP4K (2) MAPKAPK2 (MK2) (4) p38 MAPK (48) AAK1 (3) Akt (6) AMPK (2) Apoptosis (14) Aurora Kinase (1) Autophagy (9) Bcr-Abl (1) Btk (1) c-Myc (1) CaMK (1) Casein Kinase (3) CDK (6) Checkpoint Kinase (Chk) (1) COX (2) Cyclin G-associated Kinase (GAK) (2) Drug Metabolite (1) DYRK (1) EGFR (3) Endogenous Metabolite (1) Ephrin Receptor (1) ERK (16) Ferroptosis (3) FGFR (3) FLT3 (2) HSP (1) IKK (1) Interleukin Related (2) IRAK (1) Isotope-Labeled Compounds (2) Itk (2) JAK (2) JNK (3) Keap1-Nrf2 (1) LIM Kinase (LIMK) (3) MAP3K (1) MEK (2) MELK (1) MMP (1) NF-κB (12) PDGFR (1) Phosphatase (1) Phosphodiesterase (PDE) (2) PI3K (5) Pim (1) PKC (1) PROTACs (7) Raf (7) RANKL/RANK (1) Ras (1) Reference Standards (5) RET (1) Salt-inducible Kinase (SIK) (3) Ser/Thr Kinase (1) SHP2 (1) Src (6) STAT (2) TAM Receptor (2) TGF-beta/Smad (2) TNF Receptor (2) Toll-like Receptor (TLR) (1) ULK (3) VEGFR (1) Wee1 (2) Wnt (5) β-catenin (1)
By Research Areas:	Cancer (52) Cardiovascular Disease (7) Endocrinology (2) Infection (3) Inflammation/Immunology (34) Metabolic Disease (6) Neurological Disease (7)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: p38 MAPK MAP4K MNK MAPKAPK2 (MK2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107620

PD 198306	MEK	Neurological Disease
PD 198306 is a selective MAPK/ERK-kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects .

HY-P10438

TAT-Braftide	Raf	Cancer
TAT-Braftide is a peptide inhibitor designed to block the dimerization of BRAF, thereby inhibiting its kinase activity. The destruction of BRAF dimer by TAT-Braftide makes BRAF protein more susceptible to proteasome degradation, directly inhibits the activity of BRAF kinase, and reduces the activation of MAPK signaling pathway. Tat-braftide can be used for the role of RAF kinase in MAPK signaling pathway and for the study of BRAF mutant cancers .

HY-120595

JNJ-49095397 RV568	p38 MAPK Src	Inflammation/Immunology
JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma .

HY-112181

KO-947 4 Publications Verification	ERK	Cancer
KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential utility in MAPK pathway dysregulated tumors.

HY-49073

p38 MAP Kinase Inhibitor Ⅵ	p38 MAPK	Cancer
p38 MAP Kinase Inhibitor VI (compound c32) is a p38 MAPK inhibitor with an inhibition rate of 24% .

HY-142452

Pan-RAF kinase inhibitor 1	Raf	Cancer
Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B) .

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-15496

E6201 ER-806201	MEK FLT3	Cancer
E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosphorylation with an IC₅₀ value of 5.2 nM, MKK4-induced JNK phosphorylation with an IC₅₀ value of 91 nM, and MKK6-induced p38 MAPK phosphorylation with an IC₅₀ value of 19 nM. Anti-tumor and anti-psoriasis efficacy .

HY-U00324

p38 MAPK-IN-2	p38 MAPK Autophagy	Cancer
p38 MAPK-IN-2 is an inhibitor of p38 kinase.

HY-P10367

Ziptide	MAPKAPK2 (MK2) Checkpoint Kinase (Chk) AMPK	Others
Ziptide is a substrate for MAPK activated protein kinase 2 (MAPKAPK2, K_m = 5 μM), MAPKAPK3 (K_m = 30 μM), PARK (K_m = 40 μM), checkpoint kinase 1 (Chk1, K_m = 5 μM), AMP-activated protein kinase (AMPK, K_m = 75 μM), and calcium/calmodulin-dependent protein kinase II (CamKII, K_m = 300 μM) .

HY-152087

DCZ19931	ERK p38 MAPK	Cardiovascular Disease
DCZ19931 is a potent multi-targeting kinase inhibitor. DCZ19931 has anti-angiogenic effects on ocular neovascularization. DCZ19931 also inhibits ERK1/2-MAPK and p38-MAPK signaling .

HY-161293

p38-α MAPK-IN-6	p38 MAPK	Cancer
p38-α MAPK-IN-6 (compound 3a) is a p38α mitogen-activated protein kinase inhibitor .

HY-120485

Raxofelast IRFI-016	p38 MAPK ERK PKC	Cardiovascular Disease
Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H₂O₂-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), *ERK kinase* 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras** expression .

HY-Z3832

N-Methylparoxetine	Apoptosis p38 MAPK Autophagy	Cancer
N-Methylparoxetine is a derivative of Paroxetine that induces Apoptosis NSCLC cells by activating mitogen-activated protein kinase ( *MAPK*). N-Methylparoxetine has antitumor activity .

HY-145026

ERK1/2 inhibitor 4	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1) .

HY-145027

ERK1/2 inhibitor 5	ERK	Cancer
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1) .

HY-175431

p38 MAPK-IN-8	p38 MAPK	Inflammation/Immunology Cancer
p38 MAPK-IN-8 (Compound 8) is an orally active, potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor. p38 MAPK-IN-8 is promising for research of inflammatory responses, autoimmune diseases, and cancer .

HY-145025

ERK1/2 inhibitor 3	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 3 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 3 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021218912A1, compound 1) .

HY-145028

ERK1/2 inhibitor 6	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 6 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021063335A1, compound 1) .

HY-112389

p38 MAP Kinase Inhibitor III 2 Publications Verification	p38 MAPK	Inflammation/Immunology
p38 MAP Kinase Inhibitor III (compound 7h) is a p38 MAPK inhibitor with an ₅₀ of 0.9 μM. p38 MAP Kinase Inhibitor III also inhibits IL-1β and TNF-α release with ₅₀ values of 0.37 μM and 0.044 μM, respectively .

HY-N1966

(E)-Osmundacetone 2 Publications Verification	p38 MAPK JNK ERK	Neurological Disease
(E)-Osmundacetone is the isomer of Osmundacetone. Osmundacetone significantly suppresses the phosphorylation of MAPKs, including JNK, ERK, and p38 kinases. Osmundacetone has a neuroprotective effect against oxidative stress .

HY-112401

p38 MAP Kinase Inhibitor IV	p38 MAPK	Inflammation/Immunology
p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC₅₀s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively .

HY-175429

p38 MAPK-IN-7	p38 MAPK	Inflammation/Immunology
p38 MAPK-IN-7 (Compound 2) is an orally active, potent and selective p38 MAP kinase inhibitor (IC₅₀=170 nM). p38 MAPK-IN-7 is promising for research of inflammatory diseases such as rheumatoid arthritis and septic shock .

HY-12072

Lck Inhibitor 2 Publications Verification	Src	Inflammation/Immunology
Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC₅₀s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis .

HY-175433

p38 MAPK-IN-10	p38 MAPK	Inflammation/Immunology
p38 MAPK-IN-10 (Compound 4) is an orally active and potent p38 MAP kinase inhibitor (IC₅₀=570 nM). p38 MAPK-IN-10 is promising for research of chronic inflammatory diseases such as rheumatoid arthritis and Crohn’s disease .

HY-110193

SPP-86 2 Publications Verification	RET	Cancer
SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC₅₀ of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells . SPP-86 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-175432

p38 MAPK-IN-9	p38 MAPK	Inflammation/Immunology
p38 MAPK-IN-9 (Compound 15) is an orally active and highly selective p38α mitogen-activated protein kinase (p38 MAPK) inhibitor with an IC₅₀ value of 9.6 nM. p38 MAPK-IN-9 is promising for research of inflammatory diseases such as rheumatoid arthritis, septic shock, and chronic obstructive pulmonary disease (COPD) .

HY-P10436

Braftide	Raf	Cancer
Braftide is an allosteric inhibitor for BRAF kinase by targeting the dimer interface of BRAF kinase and inhibiting the formation of BRAF dimers. Braftide inhibits wild-type BRAF and oncogenic BRAF ^G469A with IC₅₀ of 364 nM and 172 nM, respectively. Braftide inhibits MAPK signaling pathway, inhibits proliferation of KRAS mutant tumor cells (EC₅₀ is 7.1 and 6.6 μM, for HCT116 and HCT-15), in combination of TAT sequence .

HY-100278

AKP-001	p38 MAPK	Inflammation/Immunology
AKP-001 is an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). AKP-001 can inhibit the production of inflammatory cytokines and can be used for research in rheumatoid arthritis and inflammatory bowel disease .

HY-148061

DB1113	PROTACs Bcr-Abl CDK Salt-inducible Kinase (SIK) Cyclin G-associated Kinase (GAK) MAP4K MAPKAPK2 (MK2) Ferroptosis ULK LIM Kinase (LIMK)	Others
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-160765

WNTinib APS-8-100-2	Wnt Apoptosis	Cancer
WNTinib (APS-8-100-2) is a multi-kinase inhibitor that selectively antagonizes β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC). WNTinib downregulates oncogenicWntsignaling by inhibiting KIT/MAPK and downstream EZH2 activation .

HY-172787

FGFR4-IN-23	FGFR Akt AMPK	Cancer
FGFR4-IN-23 (compound 48c) is a FGFR4 inhibitor with an IC₅₀ value of 2.9 nM against FGFR4 ^WT kinase. FGFR4-IN-23 inhibits the phosphorylation of FGFR4, AKT and *MAPK* .

HY-160469

INY-05-040	Akt PROTACs	Cancer
INY-05-040 is an AKT degrader that can selectively and quickly degrade all three AKT isoforms. INY-05-040 exhibits anti-cancer activity. INY-05-040 can inhibit downstream signaling and cell proliferation in 288 cancer cell lines. INY-05-040 can suppress AKT signaling and induces the stress mitogen-activated protein kinase (MAPK) c-Jun N-terminal kinase (JNK). INY-05-040 is effective for breast cancer lines with a low-baseline activation of stress MAPK pathway. INY-05-040 can be studied for anti-cancer research .

HY-136990

GLPG0259	Others	Cancer
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) cells .

HY-112345

PD-089828	FGFR PDGFR EGFR Src	Cancer
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC₅₀s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC₅₀=0.18 µM). PD-089828 also inhibits *MAPK* with an IC₅₀ of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity .

HY-P10414A

Klotho-derived peptide 1 hydrochloride KP1 (human) hydrochloride	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-P10072A

MK2-IN-5 acetate Hsp25 Kinase inhibitor acetate; Mk2 pseudosubstrate acetate	JNK HSP MAPKAPK2 (MK2) p38 MAPK ERK	Others
MK2-IN-5 (Hsp25 kinase inhibitor) acetate is a Mk2 pseudosubstrate (K_i= 8 μM). MK2-IN-5 acetate targets the protein interaction domain in the MAPK pathway. MK2-IN-5 acetate inhibits HSP25 and HSP27 phosphorylation .

HY-14974

R 1487	p38 MAPK	Inflammation/Immunology
R 1487 is an orally active and highly selective p38α mitogen-activated protein kinase inhibitor. R 1487 can be used in the study of rheumatoid arthritis .

HY-10406

Talmapimod 3 Publications Verification SCIO-469	p38 MAPK	Cancer
Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC₅₀ of 9 nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs .

HY-10406A

Talmapimod hydrochloride SCIO-469 hydrochloride	p38 MAPK	Cancer
Talmapimod (SCIO-469) hydrochloride is an orally active, selective, and ATP-competitive p38α inhibitor with an IC₅₀ of 9 nM. Talmapimod hydrochloride shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs .

HY-135906

CK2/ERK8-IN-1 2 Publications Verification	Casein Kinase ERK Pim DYRK Apoptosis	Cancer
CK2/ERK8-IN-1 is a dual *casein kinase* 2 (CK2) (K_i of 0.25 µM) and ERK8** (MAPK15, ERK7) inhibitor with IC₅₀s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (*homeodomain-interacting protein kinase* 2), and DYRK1A with K_is of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 has pro-apoptotic** efficacy .

HY-137092

IACS-13909 3 Publications Verification	SHP2 Phosphatase	Cancer
IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC₅₀ of 15.7 nM and a K_d of 32 nM. IACS-13909 is more selective for SHP2 than other phosphatases (including SHP1). IACS-13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases (RTK)-dependent cancers .

HY-P10954

Link N peptide	p38 MAPK	Others
Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases .

HY-N6246

Asperulosidic Acid	NF-κB ERK	Inflammation/Immunology Cancer
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-108645

AL 8697	p38 MAPK Autophagy	Inflammation/Immunology
AL 8697 is a specific and orally active p38α MAPK inhibitor with an IC₅₀ of 6 nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC₅₀=82 nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity .

HY-111820

CK1-IN-1	Casein Kinase p38 MAPK	Cardiovascular Disease
CK1-IN-1 (Compound 1c) is a casein kinase 1 (CK1) inhibitor with IC₅₀ values of 15 nM and 16 nM for CK1δ and CK1ε, respectively. CK1-IN-1 inhibits p38α MAPK with an IC₅₀ of 73 nM. CK1-IN-1 can be used to study cardiomyogenesis .

HY-N12726

Halociline	p38 MAPK MMP	Infection Inflammation/Immunology Cancer
Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .

HY-116035

Nimbolide 1 Publications Verification	Wnt NF-κB CDK Apoptosis	Cancer
Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-172581

Clifutinib	FLT3 Apoptosis Ras p38 MAPK PI3K Akt JAK STAT	Cancer
Clifutinib (Compound 9e) is an orally active and selective internal tandem duplication mutation of FMS-like tyrosine kinase 3 (FLT3-ITD) inhibitor with an IC₅₀ value of 15.1 nM. Clifutinib inhibits the activity of FLT3-ITD kinase and blocks the downstream RAS/MAPK, PI3K/AKT, and JAK/STAT5 signaling pathways of FLT3. Clifutinib induces apoptosis of acute myeloid leukemia (AML) cells with FLT3-ITD mutations. Clifutinib is promising for research of relapsed/refractory FLT3-ITD-positive acute myeloid leukemia .

Cat. No.	Product Name

HY-L164

Serine/Threonine Kinase Inhibitor Library

1,845 compounds

Protein serine/threonine kinases (PSKs) are protein kinases that use ATP as a high-energy donor molecule to transfer phosphate groups to serine/threonine residues of target protein. As an important signal transduction regulator, serine/threonine kinases can affect the function of target proteins by disrupting enzyme activity or binding of target proteins to other proteins. Serine/threonine kinases are involved in the regulation of immune response, cell proliferation, differentiation, apoptosis and other physiological processes. Serine/threonine kinase inhibitors are an important class of compounds that have been widely studied in cancer, chronic inflammation, autoimmune diseases, aging and other diseases.

MCE designs a unique collection of 1,845 serine/threonine kinase inhibitors, mainly targeting the receptor PKA, Akt, PKC, MAPK/ERK, etc, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases, anti-autoimmune diseases and anti-aging compounds.

HY-L010

MAPK Compound Library

825 compounds

MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. In mammalian cells, four MAPK families have been clearly characterized: ERK1/2, C-Jun N-terminal kinse/stress-activated protein kinase (JNK/SAPK) , p38 kinase and ERK5. They respond to different signals. Each MAPK-related cascade consists of three enzymes that are activated in series: a MAPK kinase kinase (MAPKKK), a MAPK kinase (MAPKK) and a MAP kinase (MAPK). MAPK signaling pathways has been implicated in the development of many human diseases including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and various types of cancers.

MCE designs a unique collection of 825 MAPK signaling pathway inhibitors that act as a useful tool for MAPK-related drug screening and disease research.

Cat. No.	Product Name	Target	Research Area

HY-P10438

TAT-Braftide	Raf	Cancer
TAT-Braftide is a peptide inhibitor designed to block the dimerization of BRAF, thereby inhibiting its kinase activity. The destruction of BRAF dimer by TAT-Braftide makes BRAF protein more susceptible to proteasome degradation, directly inhibits the activity of BRAF kinase, and reduces the activation of MAPK signaling pathway. Tat-braftide can be used for the role of RAF kinase in MAPK signaling pathway and for the study of BRAF mutant cancers .

HY-P10436

Braftide	Raf	Cancer
Braftide is an allosteric inhibitor for BRAF kinase by targeting the dimer interface of BRAF kinase and inhibiting the formation of BRAF dimers. Braftide inhibits wild-type BRAF and oncogenic BRAF ^G469A with IC₅₀ of 364 nM and 172 nM, respectively. Braftide inhibits MAPK signaling pathway, inhibits proliferation of KRAS mutant tumor cells (EC₅₀ is 7.1 and 6.6 μM, for HCT116 and HCT-15), in combination of TAT sequence .

HY-P10414A

Klotho-derived peptide 1 hydrochloride KP1 (human) hydrochloride	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

HY-P10072A

MK2-IN-5 acetate Hsp25 Kinase inhibitor acetate; Mk2 pseudosubstrate acetate	JNK HSP MAPKAPK2 (MK2) p38 MAPK ERK	Others
MK2-IN-5 (Hsp25 kinase inhibitor) acetate is a Mk2 pseudosubstrate (K_i= 8 μM). MK2-IN-5 acetate targets the protein interaction domain in the MAPK pathway. MK2-IN-5 acetate inhibits HSP25 and HSP27 phosphorylation .

HY-P10954

Link N peptide	p38 MAPK	Others
Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases .

HY-P10367

Ziptide	MAPKAPK2 (MK2) Checkpoint Kinase (Chk) AMPK	Others
Ziptide is a substrate for MAPK activated protein kinase 2 (MAPKAPK2, K_m = 5 μM), MAPKAPK3 (K_m = 30 μM), PARK (K_m = 40 μM), checkpoint kinase 1 (Chk1, K_m = 5 μM), AMP-activated protein kinase (AMPK, K_m = 75 μM), and calcium/calmodulin-dependent protein kinase II (CamKII, K_m = 300 μM) .

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model .

Cat. No.	Product Name	Target	Research Area

HY-P99463

Batiraxcept AVB-500; AVB-S6-500	TAM Receptor PI3K Akt p38 MAPK	Cancer
Batiraxcept (AVB-500; AVB-S6-500) is a selective, soluble AXL receptor and GAS6 inhibitor that targets the GAS6-AXL signaling axis. Batiraxcept is orally inactive and does not cross the blood-brain barrier. Batiraxcept competitively binds to GAS6 ((K_D <1 nM), preventing its interaction with the AXL receptor tyrosine kinase, thereby inhibiting downstream PI3K/AKT and *MAPK* signaling pathways, reducing tumor cell glycolysis, angiogenesis, and metastatic potential. Batiraxcept has demonstrated antitumor activity in preclinical models of endometrial, cholangiocarcinoma, and ovarian cancer by inhibiting tumor growth, invasion, and metastasis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1966

(E)-Osmundacetone 2 Publications Verification	Structural Classification Microorganisms Source classification Phenols Polyphenols	p38 MAPK JNK ERK
(E)-Osmundacetone is the isomer of Osmundacetone. Osmundacetone significantly suppresses the phosphorylation of MAPKs, including JNK, ERK, and p38 kinases. Osmundacetone has a neuroprotective effect against oxidative stress .

HY-N6246

Asperulosidic Acid	Iridoids Classification of Application Fields Terpenoids Source classification Rubiaceae Plants Morinda officinalis How Inflammation/Immunology Disease Research Fields	NF-κB ERK
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-116035

Nimbolide 1 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Azadirachta indica A. Juss. Plants Meliaceae Disease Research Fields Cancer	Wnt NF-κB CDK Apoptosis
Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-16558

Butein 5 Publications Verification 2’,3,4,4’-tetrahydroxy Chalcone	Structural Classification Chalcones Flavonoids other families Classification of Application Fields Anti-aging Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	EGFR Autophagy Apoptosis Phosphodiesterase (PDE)
Butein is a cAMP-specific PDE inhibitor with an IC₅₀ of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC₅₀s of 16 and 65 μM for EGFR and p60 ^c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).

HY-N0632

Esculentoside A 2 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Phytolacca acinosa Roxb. Plants Inflammation/Immunology Disease Research Fields Phytolaccaceae	COX NF-κB
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-N12726

Halociline	Structural Classification Microorganisms Marine natural products Source classification Phenols Marine microorganism	p38 MAPK MMP
Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .

HY-N1818

Deoxysappanone B 3-Deoxysappanone B	Structural Classification Leguminosae Caesalpinia sappan L. Source classification Phenols Polyphenols Plants	p38 MAPK
Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage .

HY-N6246R

Asperulosidic Acid (Standard)	Structural Classification Iridoids Terpenoids Source classification Rubiaceae Plants Morinda officinalis How	Reference Standards NF-κB ERK
Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-116035R

Nimbolide (Standard)	Triterpenes Structural Classification Terpenoids Source classification Azadirachta indica A. Juss. Plants Meliaceae	Wnt NF-κB CDK Apoptosis
Nimbolide (Standard) is the analytical standard of Nimbolide. This product is intended for research and analytical applications. Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-16558R

Butein (Standard) 2’,3,4,4’-tetrahydroxy Chalcone (Standard)	Structural Classification Chalcones Flavonoids other families Source classification Phenols Polyphenols Plants	Reference Standards EGFR Autophagy Apoptosis Phosphodiesterase (PDE)
Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).

HY-N0031

Plantamajoside 2 Publications Verification	Plantaginaceae Structural Classification Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plantago asiatica L. Plants Inflammation/Immunology Disease Research Fields	NF-κB PI3K Akt Apoptosis Autophagy p38 MAPK Src
Plantamajoside is an orally active phenylpropanoid glycoside. Plantamajoside can be isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside inactivates NF-κB, PI3K/akt, induces Apoptosis, and improves Autophagy. Plantamajoside regulates *MAPK, integrin-linked kinase/c-Src*. Plantamajoside inhibits multiple cancers, improves lung and kidney damage. Plantamajoside has neuroprotective and anti-inflammatory effects .

HY-N0632R

Esculentoside A (Standard)	Triterpenes Structural Classification Terpenoids Source classification Phytolacca acinosa Roxb. Plants Phytolaccaceae	Reference Standards COX NF-κB
Esculentoside A (Standard) is the analytical standard of Esculentoside A. This product is intended for research and analytical applications. Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-N0818

Chikusetsusaponin Iva 2 Publications Verification Calenduloside F	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Amaranthaceae Plants Alternanthera philoxeroides (Mart.) Griseb. Disease Research Fields	Keap1-Nrf2
Chikusetsusaponin IVa is an orally active protein kinase activator. Chikusetsusaponin IVa binds to YAP with a K_D value of 0.388 mM. Chikusetsusaponin IVa reduces inflammatory mediators (IL-6, IL-10, COX-2) expression, NO production, promotes ROS generation, induces Apoptosis, inhibits *MAPK, TAZ, and regulates Nrf2, JAK/STAT. Chikusetsusaponin Iva has anti-H9N2 AIV* and anti-endometrial cancer activities. Chikusetsusaponin Iva shows anti-inflammatory, hepatoprotective and osteoprotective effects .

HY-N0031R

Plantamajoside (Standard)	Plantaginaceae Structural Classification Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plantago asiatica L. Plants	Reference Standards NF-κB PI3K Apoptosis Autophagy p38 MAPK Src
Plantamajoside (Standard) is the analytical standard of Plantamajoside. This product is intended for use in research and analytical applications. Plantamajoside is an orally active phenylpropanoid glycoside. Plantamajoside can be isolated from Plantago asiatica L.(Plantaginaceae). Plantamajoside inactivates NF-κB, PI3K/akt, induces Apoptosis, and improves Autophagy. Plantamajoside regulates *MAPK, integrin-linked kinase/c-Src*. Plantamajoside inhibits multiple cancers, improves lung and kidney damage. Plantamajoside has neuroprotective and anti-inflammatory effects .

HY-W100287

Murrayafoline A	Structural Classification Alkaloids Murraya tetramera C. C. Huang Source classification Rutaceae Carbazole Alkaloids Plants	NF-κB p38 MAPK Interleukin Related IKK JNK β-catenin Wnt
Murrayafoline A is a carbazole alkaloid that can be extracted from Murraya tetramera. Murrayafoline A directly targets Specificity protein 1 (Sp1), thereby inhibiting NF-κB and *MAPK* signaling pathways. Murrayafoline a induces a G0/G1-phase arrest in platelet-derived growth factor (PDGF)-stimulated vascular smooth muscle cells. Murrayafoline A attenuates the Wnt/β-catenin pathway by promoting the degradation of intracellular β-catenin proteins. Murrayafoline A enhances the contraction of rat ventricular myocytes and L-type calcium current by activating protein kinase C. Murrayafoline A inhibits LPS (HY-D1056)-induced neuroinflammation in vivo. Murrayafoline A can be used for the study of inflammation, vascular complications and colon cancer .

Species:	Human (39) Mouse (2)
Tag:	His (19) Tag Free (9) Strep (2) GST (17) Flag (2)
Source:	Sf9 insect cells (2) Sf9 insect cells (20) P. pastoris (1) E. coli (18)

Cat. No.	Compare	Product Name	Species	Source

HY-P701678

	ERK1 Protein, Human (GST) MAPK3; Mitogen-activated protein Kinase 3; MAP Kinase 3; MAPK 3; ERT2; Extracellular signal-regulated Kinase 1; ERK-1; Insulin-stimulated MAP2 Kinase; MAP Kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 Kinase; p44-ERK1	Human	E. coli
	ERK1 protein is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. ERK1 Protein, Human (GST) is the recombinant human-derived ERK1 protein, expressed by E. coli , with N-GST labeled tag.

HY-P701803

	MAPK4 Protein, Human (sf9, His, GST) MAPK4; Mitogen-activated protein Kinase 4; MAP Kinase 4; MAPK 4; Extracellular signal-regulated Kinase 4; ERK-4; MAP Kinase isoform p63; p63-MAPK	Human	Sf9 insect cells
	MAPK4, an atypical MAPK protein, phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5, forming a complex with intricate phosphorylation events. Interaction with MAPKAPK5 leads to ERK3/MAPK6 phosphorylation at Ser-189, activating MAPKAPK5, which reciprocally phosphorylates ERK3/MAPK6. The specific cellular role of this interplay, while unclear, suggests ERK3's potential involvement in promoting entry into the cell cycle. MAPK4 Protein, Human (sf9, His, GST) is the recombinant human-derived MAPK4 protein, expressed by sf9 insect cells , with N-8*His, N-GST labeled tag.

HY-P701679

	ERK3 Protein, Human (L290V) MAPK6; Mitogen-activated protein Kinase 6; MAP Kinase 6; MAPK 6; Extracellular signal-regulated Kinase 3; ERK-3; MAP Kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V) is the recombinant human-derived ERK3 protein, expressed by E. coli , with tag free.

HY-P701680

	ERK3 Protein, Human (L290V, His) MAPK6; Mitogen-activated protein Kinase 6; MAP Kinase 6; MAPK 6; Extracellular signal-regulated Kinase 3; ERK-3; MAP Kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V, His) is the recombinant human-derived ERK3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702735

	MAPK1/ERK2 Protein, Human (Flag, His) MAPK1; mitogen-activated protein Kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41MAPK; ERK-2; MAPK 2; p42-MAPK; MAP Kinase 1; MAP Kinase 2; MAP Kinase isoform p42; protein tyrosine Kinase ERK2; mitogen-activated protein Kinase 2; extracellular signal-regulated Kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1 Protein, Human (Flag, His) is the recombinant human-derived MAPK1, expressed by E. coli, with His, Flag labeled tag.

HY-P704008

	MAPK1/ERK2 Protein, Human (Inactive, GST) MAPK1; mitogen-activated protein Kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41MAPK; ERK-2; MAPK 2; p42-MAPK; MAP Kinase 1; MAP Kinase 2; MAP Kinase isoform p42; protein tyrosine Kinase ERK2; mitogen-activated protein Kinase 2; extracellular signal-regulated Kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1/ERK2 Protein, Human (Inactive, GST) is the recombinant human-derived MAPK1/ERK2 protein, expressed by E. coli, with N-GST labeled tag.

HY-P705421

	JNK1 Protein, Mouse (Active, sf9, GST) MAP Kinase 8; MAPK 8; Stress-activated protein Kinase JNK1; c-Jun N-terminal Kinase 1; MAPK8	Mouse	Sf9 insect cells

HY-P701801

	MAP4K6 Protein, Human (sf9, GST) MINK1; Misshapen-like Kinase 1; GCK family Kinase MiNK; MAPK/ERK Kinase Kinase Kinase 6; MEK Kinase Kinase 6; MEKKK 6; Misshapen/NIK-related Kinase; Mitogen-activated protein Kinase Kinase Kinase Kinase 6	Human	Sf9 insect cells
	MAP4K6 protein is a key serine/threonine kinase that negatively regulates Ras-related Rap2-mediated signaling, affecting neuronal structure and AMPA receptor trafficking. Its importance is underlined by its important role in regulating synaptic density, dendritic complexity, and surface AMPA receptor expression in hippocampal neurons. MAP4K6 Protein, Human (sf9, GST) is the recombinant human-derived MAP4K6 protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P701791

	JNK3 Protein, Human (His) MAPK10; Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; Stress-activated protein Kinase JNK3; c-Jun N-terminal Kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human (His) is the recombinant human-derived JNK3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703924

	p38 gamma/MAPK12 Protein, Human (Active, sf9, GST) Mitogen-activated protein Kinase 12; MAP Kinase 12; MAPK 12; Extracellular signal-regulated Kinase 6 (ERK-6); Mitogen-activated protein Kinase p38 gamma (MAP Kinase p38 gamma); Stress-activated protein Kinase 3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (Active, sf9, GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells, with N-GST labeled tag.

HY-P701814

	MKNK2 Protein, Human MKNK2; MAP Kinase-interacting serine/threonine-protein Kinase 2; MAP Kinase signal-integrating Kinase 2; MAPK signal-integrating Kinase 2; Mnk2	Human	E. coli
	MKNK2 is a serine/threonine protein kinase that centrally affects cellular processes by phosphorylating SFPQ/PSF, HNRNPA1, and EIF4E. MKNK2 sits at the intersection of environmental stress and cytokine signaling and regulates translation by enhancing the affinity of EIF4E for the mRNA cap, thereby affecting the translation machinery. MKNK2 Protein, Human is the recombinant human-derived MKNK2 protein, expressed by E. coli , with tag free.

HY-P701705

	ASK1 Protein, Human (His) MAP3K5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	Human	E. coli
	ASK1 protein is a key serine/threonine kinase in the MAP kinase pathway, coordinating cellular responses to environmental changes and affecting cell fate, differentiation, and survival. ASK1 is a key player in apoptosis and promotes mitochondria-dependent caspase activation. ASK1 Protein, Human (His) is the recombinant human-derived ASK1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P702934

	MAPK15 Protein, Human (sf9, GST, StrepⅡ) Mitogen-activated protein Kinase 15 Curated; MAPK 15; Extracellular signal-regulated Kinase 7 (ERK-7); Extracellular signal-regulated Kinase 8 (ERK-8); MAPK15 Imported; ERK7 By similarity	Human	Sf9 insect cells
	MAPK15 Protein, Human (sf9, GST, StrepII) is the recombinant human-derived MAPK15, expressed by Sf9 insect cells , with C-Strep, N-GST labeled tag. ,

HY-P701815

	MKNK2 Protein, Human (His) MKNK2; MAP Kinase-interacting serine/threonine-protein Kinase 2; MAP Kinase signal-integrating Kinase 2; MAPK signal-integrating Kinase 2; Mnk2	Human	E. coli
	MKNK2 is a serine/threonine protein kinase that centrally affects cellular processes by phosphorylating SFPQ/PSF, HNRNPA1, and EIF4E. MKNK2 sits at the intersection of environmental stress and cytokine signaling and regulates translation by enhancing the affinity of EIF4E for the mRNA cap, thereby affecting the translation machinery. MKNK2 Protein, Human (His) is the recombinant human-derived MKNK2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701790

	JNK3 Protein, Human (364a.a, His) MAPK10; Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; Stress-activated protein Kinase JNK3; c-Jun N-terminal Kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human is the recombinant human-derived JNK3 protein, expressed by E. coli , with tag free.

HY-P700593

	MAP3K1 Protein, Mouse (His) MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK Kinase Kinase 1; MAPK/ERK Kinase Kinase 1; MEK Kinase 1; mitogen-activated protein Kinase Kinase Kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein Kinase Kinase Kinase 1	Mouse	E. coli
	MAP3K1 is a key component of the protein kinase signal transduction cascade and plays a crucial role in cell signaling pathways.Through its kinase activity, MAP3K1 coordinates the activation of the ERK and JNK kinase pathways by phosphorylating MAP2K1 and MAP2K4.MAP3K1 Protein, Mouse (His) is the recombinant mouse-derived MAP3K1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P701813

	MKNK1 Protein, Human (sf9, GST) MKNK1; MAP Kinase-interacting serine/threonine-protein Kinase 1; MAP Kinase signal-integrating Kinase 1; MAPK signal-integrating Kinase 1; Mnk1	Human	Sf9 insect cells
	MKNK1 (MAP Kinase Interacting Serine/Threonine Kinase 1) plays a central role in coordinating cellular responses to environmental stress and cytokines. It exerts regulatory control over translation processes by phosphorylating EIF4E, enhancing its affinity for mRNA cap structures with 7-methylguanosine. This highlights MKNK1's crucial involvement in finely tuning translation machinery in response to diverse cellular stimuli. MKNK1 Protein, Human (sf9, GST) is the recombinant human-derived MKNK1 protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P703250

	MAP4K3 Protein, Human (sf9, GST, Flag) Mitogen-activated protein Kinase Kinase Kinase Kinase 3; Germinal center Kinase-related protein Kinase; GLK; MAPK/ERK Kinase Kinase Kinase 3; MEK Kinase Kinase 3; MEKKK 3; MAP4K3; RAB8IPL1; Homo sapiens; Human; GLK; Kinase; Serine/threonine-protein Kinase; Transferase; 2.7.11.1	Human	Sf9 insect cells
	MAP4K3 Protein, Human (sf9, GST, Flag) is the recombinant human-derived MAP4K3, expressed by sf9 insect cells , with GST, Flag labeled tag. ,

HY-P702662

	MAPKAPK2 Protein, Human (323a.a) MAPKAPK2; mitogen-activated protein Kinase-activated protein Kinase 2; MAP Kinase-activated protein Kinase 2; MAPKAP Kinase 2; MAPK-activated protein Kinase 2; MK2; MK-2; MAPKAP-K2	Human	E. coli
	The MAPKAPK2 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production, endocytosis, cytoskeletal reorganization, cell migration, cell cycle control, chromatin remodeling, DNA damage response, and transcriptional regulation. MAPKAPK2 Protein, Human (323a.a) is the recombinant human-derived MAPKAPK2, expressed by E. coli, with tag Free labeled tag.

HY-P701804

	MAPKAPK2 Protein, Human MAPKAPK2; MAP Kinase-activated protein Kinase 2; MAPK-activated protein Kinase 2; MAPKAP Kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2	Human	E. coli
	The MAPKAPK2 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production, endocytosis, cytoskeletal reorganization, cell migration, cell cycle control, chromatin remodeling, DNA damage response, and transcriptional regulation. MAPKAPK2 Protein, Human is the recombinant human-derived MAPKAPK2 protein, expressed by E. coli , with tag free and ΔH217-P237, S216G mutation.

HY-P701730

	P38β Protein, Human (sf9) MAPK11; Mitogen-activated protein Kinase 11; MAP Kinase 11; MAPK 11; Mitogen-activated protein Kinase p38 beta; MAP Kinase p38 beta; p38b; Stress-activated protein Kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (sf9) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with tag free.

HY-P701731

	P38β Protein, Human (sf9, GST) MAPK11; Mitogen-activated protein Kinase 11; MAP Kinase 11; MAPK 11; Mitogen-activated protein Kinase p38 beta; MAP Kinase p38 beta; p38b; Stress-activated protein Kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (sf9, GST) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P704064

	MAP2K4 Protein, Human (sf9, His, StrepⅡ, GST) Dual specificity mitogen-activated protein Kinase Kinase 4; MAP Kinase Kinase 4; MAPKK 4; JNK-activating Kinase 1; MAPK/ERK Kinase 4 (MEK 4); SAPK/ERK Kinase 1 (SEK1); Stress-activated protein Kinase Kinase 1 (SAPK Kinase 1; SAPKK-1; SAPKK1); c-Jun N-terminal Kinase Kinase 1 (JNKK)	Human	Sf9 insect cells
	The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (sf9, His, StrepⅡ, GST) is the recombinant human-derived MAP2K4 protein, expressed by Sf9 insect cells, with N-His and N-GST and N-StrepⅡ labeled tag.

HY-P700592

	MAP2K6 Protein, Human (sf9, His) MAP2K6; mitogen-activated protein Kinase Kinase 6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; protein Kinase, mitogen-activated, Kinase 6 (MAP Kinase Kinase 6); EC 2.7.12.2; Dual specificity mitogen-activated protein Kinase Kinase 6; MAP Kinase Kinase 6; MAPK/ERK Kinase 6	Human	Sf9 insect cells
	The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K6 Protein, Human (sf9, His) is the recombinant human-derived MAP2K6 protein, expressed by sf9 insect cells , with N-6*His labeled tag.

HY-P701805

	MAPKAPK2 Protein, Human (His) MAPKAPK2; MAP Kinase-activated protein Kinase 2; MAPK-activated protein Kinase 2; MAPKAP Kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2	Human	E. coli
	The MAPKAPK2 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production, endocytosis, cytoskeletal reorganization, cell migration, cell cycle control, chromatin remodeling, DNA damage response, and transcriptional regulation. MAPKAPK2 Protein, Human (His) is the recombinant human-derived MAPKAPK2 protein, expressed by E. coli , with N-6*His labeled tag and ΔH217-P237, S216G mutation.

HY-P700589

	MAP2K4 Protein, Human (P. pastoris, His-GST) MAP2K4; mitogen-activated protein Kinase Kinase 4; SERK1; dual specificity mitogen-activated protein Kinase Kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK Kinase 1; MAPK/ERK Kinase 4; SAPK/ERK Kinase 1; MAP Kinase Kinase 4; JNK-activated Kinase 1; JNK activating Kinase 1; JNK-activating Kinase 1; c-Jun N-terminal Kinase Kinase 1; stress-activated protein Kinase Kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1	Human	P. pastoris
	The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (P. pastoris, His-GST) is the recombinant human-derived MAP2K4 protein, expressed by P. pastoris , with N-6*His, N-GST labeled tag.

HY-P702841

	MAP2K4 Protein, Human (sf9) MAP2K4; mitogen-activated protein Kinase Kinase 4; SERK1; dual specificity mitogen-activated protein Kinase Kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK Kinase 1; MAPK/ERK Kinase 4; SAPK/ERK Kinase 1; MAP Kinase Kinase 4; JNK-activated Kinase 1; JNK activating Kinase 1; JNK-activating Kinase 1; c-Jun N-terminal Kinase Kinase 1; stress-activated protein Kinase Kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1	Human	Sf9 insect cells
	The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (sf9) is the recombinant human-derived MAP2K4 protein, expressed by sf9 insect cells , tag free.

HY-P702663

	MAPKAPK3 Protein, Human (Active, sf9, GST) MAPKAPK3; mitogen-activated protein Kinase-activated protein Kinase 3; MAP Kinase-activated protein Kinase 3; 3pK; 3PK; MAPKAP3; MAPKAP Kinase 3; chromosome 3p Kinase; MAPK-activated protein Kinase 3; MK-3; MAPKAP-K3; MAPKAPK-3	Human	Sf9 insect cells
	The MAPKAPK3 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production and endocytosis. It is phosphorylated by p38-alpha/MAPK14 during stress, targets specific substrates, and has similarities to MAPKAPK2 but is less active. MAPKAPK3 Protein, Human (Active, sf9, GST) is the recombinant human-derived MAPKAPK3, expressed by Sf9 insect cells, with GST labeled tag.

HY-P76532

	p38 gamma/MAPK12 Protein, Human (sf9) Mitogen-activated protein Kinase 12; Extracellular signal-regulated Kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells, with tag free.

HY-P75223

	MAPK1/ERK2 Protein, Human (sf9, His) Mitogen-activated protein Kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK	Human	Sf9 insect cells
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1/ERK2 Protein, Human (sf9, His) is the recombinant human-derived ERK2 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P76533

	p38 gamma/MAPK12 Protein, Human (sf9, His-GST) Mitogen-activated protein Kinase 12; Extracellular signal-regulated Kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9, His-GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P73334

	p38 delta/MAPK13 Protein, Human (sf9, GST) Mitogen-activated protein Kinase 13; MAPK 13; PRKM13; SAPK4	Human	Sf9 insect cells
	The p38 delta/MAPK13 protein is an important serine/threonine kinase in the MAP kinase pathway. It coordinates cellular responses to stimuli such as cytokines or stress and directly activates the transcription factors ELK1 and ATF2. In this cascade, p38 MAPK (including MAPK13) each phosphorylates approximately 200 to 300 substrates. p38 delta/MAPK13 Protein, Human (sf9, GST) is the recombinant human-derived p38 delta/MAPK13 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P73848

	JNK1 Protein, Human (sf9, GST) Mitogen-activated protein Kinase 8; MAPK 8; JNK-46; JNK1; PRKM8	Human	Sf9 insect cells
	JNK1 is a multifunctional serine/threonine protein kinase that complexly regulates multiple cellular processes, including cell proliferation, apoptosis, and differentiation. JNK1 is activated by MAP2K4/MKK4 and MAP2K7/MKK7, phosphorylates AP-1 components, and affects transcriptional activity. JNK1 Protein, Human (sf9, GST) is the recombinant human-derived JNK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P73335

	p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) Mitogen-activated protein Kinase 14; MAPK 14; CSBP; MXI2; SAPK2A	Human	Sf9 insect cells
	The p38 α/MAPK14 protein is an important serine/threonine kinase in the MAP kinase pathway. It can respond to stimuli such as cytokines or stress and directly activate transcription factors. In this cascade, p38 MAPK each phosphorylates approximately 200 to 300 substrates, including the downstream kinases RPS6KA5/MSK1 and RPS6KA4/MSK2, which are critical for immediate early gene induction. p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) is the recombinant human-derived p38 alpha/MAPK14 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P701773

	RSK2 Protein, Human RPS6KA3; Ribosomal protein S6 Kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 Kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein Kinase 1; ISPK-1; MAP Kinase-activated protein Kinase 1b; MAPK-activated protein Kinase 1b; MAPKAP Kinase 1b; MAPKAPK-1b; Ribosomal S6 Kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human is the recombinant human-derived RSK2 protein, expressed by E. coli , with tag free.

HY-P701774

	RSK2 Protein, Human (His) RPS6KA3; Ribosomal protein S6 Kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 Kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein Kinase 1; ISPK-1; MAP Kinase-activated protein Kinase 1b; MAPK-activated protein Kinase 1b; MAPKAP Kinase 1b; MAPKAPK-1b; Ribosomal S6 Kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human (His) is the recombinant human-derived RSK2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701771

	RSK1 Protein, Human (sf9) RPS6KA1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAPK-1a; Ribosomal S6 Kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (sf9) is the recombinant human-derived RSK1 protein, expressed by sf9 insect cells , with tag free.

HY-P701772

	RSK1 Protein, Human (sf9, His) RPS6KA1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAPK-1a; Ribosomal S6 Kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (sf9, His) is the recombinant human-derived RSK1 protein, expressed by sf9 insect cells , with N-8*His labeled tag.

HY-P702664

	MAPKAPK5 Protein, Human (sf9, GST) MAPKAPK5; MAPK activated protein Kinase 5; MK5; MK-5; NCFD; PRAK; MAPKAP-K5	Human	Sf9 insect cells
	MAPKAPK5 Protein, Human (sf9, GST) is the recombinant human-derived MAPKAPK5, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P70931

	MAPKSP1 Protein, Human (His) Ragulator Complex Protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; Mp1; Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; Mitogen-Activated Protein Kinase Scaffold Protein 1; LAMTOR3; MAP2K1IP	Human	E. coli
	The MAPKSP1 protein, also known as porphobilinogen deaminase (HMBS), is crucial in the heme biosynthetic pathway and catalyzes the sequential polymerization of four porphobilinogen molecules to form hydroxymethyl bixane. The process begins with the assembly of the dipyrromethane cofactor of porphobilinogen or preuroporphyrinogen. MAPKSP1 Protein, Human (His) is the recombinant human-derived MAPKSP1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70921

	MBIP Protein, Human (His) MAP3K12-Binding Inhibitory Protein 1; MAPK Upstream Kinase-Binding Inhibitory Protein; MUK-Binding Inhibitory Protein; MBIP	Human	E. coli
	MBIP protein inhibits MAP3K12 activity and prevents activation of the JNK/SAPK pathway. It is an important component of the ATAC complex, a histone acetyltransferase complex targeting histones H3 and H4. MBIP Protein, Human (His) is the recombinant human-derived MBIP protein, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-121605S

RL71-d6

RL71-d₆ is a deuterium labeled RL71 (HY-121605). RL71 is a curcuminoid anticancer agent that exhibits potent cytotoxicity against a variety of ER-negative breast cancer cells. RL71 (1 μM) induces cell cycle arrest in the G2/M phase and induces apoptosis in SKBr3 cells. RL7 also decreases HER2/neu phosphorylation and increases p27. RL71 also significantly reduced the phosphorylation of Akt and transiently increased the stress kinases JNK1/2 and p38 MAPK. Furthermore, RL71 exhibited anti-angiogenic potential in vitro, inhibiting the migration of HUVEC cells and the ability of these cells to form tubular networks .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80393

	ERK1/2 Antibody (YA453) 3 Publications Verification MAP Kinase 3; MAPK 3; ERK-1; p44-MAPK; MAP Kinase 1; MAPK 1; ERK-2; p42-MAPK	WB, ICC/IF, IP, FC	Human, Mouse, Rat
	ERK1/2 Antibody (YA453) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERK1/2.

HY-P85835

	ERK2 Antibody (YA5527) MAPK1; ERK2; PRKM1; PRKM2; Mitogen-activated protein Kinase 1; MAP Kinase 1; MAPK 1; ERT1; Extracellular signal-regulated Kinase 2; ERK-2; MAP Kinase isoform p42; p42-MAPK; Mitogen-activated protein Kinase 2; MAP Kinase 2; MAPK 2	WB, ICC/IF, ELISA	Human, Mouse, Rat
	ERK2 Antibody (YA5527) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ERK2.

HY-P85152

	MAPK6/ERK3 Antibody (YA4844) MAPK6; ERK3; PRKM6; Mitogen-activated protein Kinase 6; MAP Kinase 6; MAPK 6; Extracellular signal-regulated Kinase 3; ERK-3; MAP Kinase isoform p97; p97-MAPK	WB, FC, ELISA	Human
	MAPK6/ERK3 Antibody (YA4844) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MAPK6/ERK3.

HY-P86354

	ERK5 Antibody (YA6046) MAPK7; BMK1; ERK5; PRKM7; Mitogen-activated protein Kinase 7; MAP Kinase 7; MAPK 7; Big MAP Kinase 1; BMK-1; Extracellular signal-regulated Kinase 5; ERK-5	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	ERK5 Antibody (YA6046) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERK5.

HY-P82888

	MEKK3 Antibody (YA2633) MAP/ERK Kinase Kinase 3; MAP3K3; MAPK/ERK Kinase Kinase 3; MAPKKK3; MEK Kinase 3; MEKK 3; MEKK3; Mitogen activated protein Kinase Kinase Kinase 3	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	MEKK3 Antibody (YA2633) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2633), targeting MEKK3, with a predicted molecular weight of 71 kDa (observed band size: 71 kDa). MEKK3 Antibody (YA2633) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P86387

	ERK1/2 Antibody (YA6079) MAPK3; ERK1; PRKM3; Mitogen-activated protein Kinase 3; MAP Kinase 3; MAPK 3; ERT2; Extracellular signal-regulated Kinase 1; ERK-1; Insulin-stimulated MAP2 Kinase; MAP Kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 Kinase; p	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	ERK1/2 Antibody (YA6079) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERK1/2.

HY-P81378

	MAP4K4/NIK Antibody (YA1123) MAP4K4; HGK, KIAA0687, NIK; Mitogen-activated protein Kinase Kinase Kinase Kinase 4; HPK/GCK-like Kinase HGK; MAPK/ERK Kinase Kinase Kinase 4 (MEK Kinase Kinase 4; MEKKK 4); Nck-interacting Kinase	IHC-P	Human
	MAP4K4/NIK Antibody (YA1123) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAP4K4/NIK.

HY-P85200

	MAP4K4/NIK Antibody (YA4892) MAP4K4; HGK; KIAA0687; NIK; Mitogen-activated protein Kinase Kinase Kinase Kinase 4; HPK/GCK-like Kinase HGK; MAPK/ERK Kinase Kinase Kinase 4; MEK Kinase Kinase 4; MEKKK 4; Nck-interacting Kinase	WB, ELISA	Human
	MAP4K4/NIK Antibody (YA4892) is a mouse-derived and non-conjugated monoclonal antibody, targeting to HGK. It can be applicated for WB, ELISA assays, in the background of human.

HY-P80214

	MAPKAPK2 Antibody (YA304) MAP Kinase activated protein Kinase 2 antibody; MAP Kinase-activated protein Kinase 2 antibody; MAPK activated protein Kinase 2 antibody; MAPK-activated protein Kinase 2 antibody; MAPK2_HUMAN antibody; MAPKAP K2 antibody; MAPKAP Kinase 2 antibody; MAPKAPK 2 antibody; MAPKAPK-2 antibody; MAPKAPK2 antibody; Mitogen activated protein Kinase activated protein Kinase 2 antibody; MK 2 antibody; MK2 antibody	WB, IP	Human, Mouse, Rat
	MAPKAPK2 Antibody (YA304) is a non-conjugated and Rabbit origined monoclonal antibody about 46 kDa, targeting to MAPKAP Kinase 2. It can be used for WB,IP assays with tag free, in the background of Human, Mouse,Rat.

HY-P86654

	ERK1/2 Antibody (YA6346) ERK1+ERK2; ERK 1; ERK 2; ERK-2; ERK1; ERK2; ERT1; ERT2; Extracellular signal regulated Kinase 1; Extracellular signal regulated Kinase 2; Extracellular signal-regulated Kinase 2; HS44KDAP; HUMKER1A; Insulin stimulated MAP2 Kinase; MAP Kinase 1; MAP Kinase 2; MAP Kinase isoform p42; MAP Kinase isoform p44; MAPK 1; MAPK 2; MAPK 3; MAPK1; MAPK2; MAPK3; MGC20180; Microtubule associated protein 2 Kinase; Mitogen activated protein Kinase 1; Mitogen activated protein Kinase 2; Mitogen activated protein Kinase 3; Mitogen-activated protein Kinase 1; Mitogen-activated protein Kinase 2; MK01_HUMAN; MK03_HUMAN; p38; p40; p41; p41MAPK; p42 MAPK; p42-MAPK; p42MAPK; p44 ERK1; p44 MAPK; p44ERK1; p44MAPK; PRKM 1; PRKM 2; PRKM 3; PRKM1; PRKM2; PRKM3; Protein Kinase mitogen activated 1; Protein Kinase mitogen activated 2; Protein Kinase mitogen activated 3; Protein tyrosine Kinase ERK 2.	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Human, Mouse, Rat
	ERK1/2 Antibody (YA6346) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERK1/2. It can be applicated for WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC assays, in the background of human, mouse, rat.

HY-P83470

	MEKK2 Antibody (YA3215) MAP3K2; MAPKKK2; MEKK2; Mitogen-activated protein Kinase Kinase Kinase 2; MAPK/ERK Kinase Kinase 2; MEK Kinase 2; MEKK 2	WB, ICC/IF, IP	Human, Mouse, Rat
	MEKK2 Antibody (YA3215) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3215), targeting MEKK2, with a predicted molecular weight of 70 kDa (observed band size: 72 kDa). MEKK2 Antibody (YA3215) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P85273

	MEKK2 Antibody (YA4965) MAP3K2; MAPKKK2; MEKK2; Mitogen-activated protein Kinase Kinase Kinase 2; MAPK/ERK Kinase Kinase 2; MEK Kinase 2; MEKK 2	WB, ICC/IF, ELISA	Human
	MEKK2 Antibody (YA4965) is a mouse-derived and non-conjugated monoclonal antibody, targeting to MAP3K2. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human.

HY-P83325

	MAPKAP Kinase 3 Antibody (YA3070) MAPKAPK3; MAP Kinase-activated protein Kinase 3; MAPK-activated protein Kinase 3; MAPKAP Kinase 3; MAPKAP-K3; MAPKAPK-3; MK-3; Chromosome 3p Kinase; 3pK	WB, IP	Human
	MAPKAP Kinase 3 Antibody (YA3070) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3070), targeting MAPKAP Kinase 3, with a predicted molecular weight of 43 kDa (observed band size: 43 kDa). MAPKAP Kinase 3 Antibody (YA3070) can be used for WB, IP experiment in human background.

HY-P86225

	Phospho-Erk 1/2(Thr202/Tyr204) Antibody (YA5917) MAPK3; ERK1; PRKM3; Mitogen-activated protein Kinase 3; MAP Kinase 3; MAPK 3; ERT2; Extracellular signal-regulated Kinase 1; ERK-1; Insulin-stimulated MAP2 Kinase; MAP Kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 Kinase; p	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-Erk 1/2(Thr202/Tyr204) Antibody (YA5917) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Erk 1/2(Thr202/Tyr204).

HY-P85717

	JNK2 Antibody (YA5409) Mitogen-activated protein Kinase 9; MAP Kinase 9; MAPK 9; JNK-55; Stress-activated protein Kinase 1a; SAPK1a; Stress-activated protein Kinase JNK2; c-Jun N-terminal Kinase 2;	IHC-P	Human, Mouse, Rat
	JNK2 Antibody (YA5409) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to JNK2.

HY-P80549

	ASK1 Antibody MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	WB, IHC-P, ICC/IF, FC	Human, Mouse
	ASK1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 155 kDa, targeting to ASK1. It can be used for WB,IHC-P,ICC/IF,FC assays with tag free, in the background of Human, Mouse.

HY-P83469

	MEK3 Antibody (YA3214) AW212142; dual specificity mitogen activated protein Kinase Kinase 3; Dual specificity mitogen activated protein Kinase Kinase 6; Dual specificity mitogen-activated protein Kinase Kinase 3; MAP Kinase Kinase 3; MAP Kinase Kinase 6; map2k3; MAP2K6; MAPK ERK Kinase 3; MAPK/ERK Kinase 3; MAPK/ERK Kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; Mitogen activated protein Kinase Kinase 3; Mitogen activated protein Kinase Kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein Kinase; mitogen activated; Kinase 6 (MAP Kinase Kinase 6); protein Kinase; mitogen-activated; Kinase 3; SAPK Kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein Kinase Kinase 2; Stress activated protein Kinase Kinase 3; Stress-activated protein Kinase Kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat
	MEK3 Antibody (YA3214) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3214), targeting MEK3, with a predicted molecular weight of 39 kDa (observed band size: 38-40 kDa). MEK3 Antibody (YA3214) can be used for WB, ICC/IF,IP experiment in human, mouse, rat background.

HY-P86106

	JNK2 Antibody (YA5798) MAPK9; JNK2; PRKM9; SAPK1A; Mitogen-activated protein Kinase 9; MAP Kinase 9; MAPK 9; JNK-55; Stress-activated protein Kinase 1a; SAPK1a; Stress-activated protein Kinase JNK2; c-Jun N-terminal Kinase 2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	JNK2 Antibody (YA5798) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to JNK2.

HY-P85783

	Kininogen 1 Antibody (YA5475) Dual specificity mitogen-activated protein Kinase Kinase 5; MAP Kinase Kinase 5; MAPKK 5; MAPK/ERK Kinase 5; MEK 5;	WB	Human, Mouse, Rat
	Kininogen 1 Antibody (YA5475) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Kininogen 1. It can be applicated for WB assays, in the background of human, mouse, rat.

HY-P85237

	JNK3 Antibody (YA4929) MAPK10; JNK3; JNK3A; PRKM10; SAPK1B; Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; Stress-activated protein Kinase JNK3; c-Jun N-terminal Kinase 3	WB, ICC/IF, ELISA	Human, Mouse
	JNK3 Antibody (YA4929) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to JNK3.

HY-P85046

	ASK1 Antibody (YA4738) MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	WB, IHC-P, ICC/IF, FC, ELISA	Human
	ASK1 Antibody (YA4738) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to ASK1.

HY-P86322

	ASK1 Antibody (YA6014) MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse
	ASK1 Antibody (YA6014) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ASK1.

HY-P80792

	Phospho-ASK1 (Ser966) Antibody MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	WB, IHC-P	Human, Mouse, Rat
	Phospho-ASK1 (Ser966) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 155 kDa, targeting to Phospho-ASK1 (Ser966). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P86156

	MAPKAPK2 Antibody (YA5848) MAPKAPK2; MAP Kinase-activated protein Kinase 2; MAPK-activated protein Kinase 2; MAPKAP Kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MAPKAPK2 Antibody (YA5848) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAPKAPK2.

HY-P85516

	MEK1 Antibody (YA5208) AA589381; Dual specificity mitogen-activated protein Kinase Kinase 1; Dual specificity mitogen-activated protein Kinase Kinase 2; ERK activator Kinase 1; ERK activator Kinase 2; FLJ26075; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP2K1; MAP2K2; MAPK/ERK Kinase 1; MAPK/ERK Kinase 2; MAPKK 1; MAPKK1; MAPKK2; MEK 1; MEKK1; Mitogen activated protein Kinase Kinase 1; Mitogen activated protein Kinase Kinase 2; Mitogen-activated protein Kinase Kinase 2, p45; MK2; MKK 1; MKK 2; MKK1; MKK2; MP2K1_HUMAN; PRKMK 1; PRKMK 2; Prkmk1; Prkmk2; protein Kinase, mitogen-activated, Kinase 1; MAP Kinase Kinase 1; Protein Kinase, mitogen-activated, Kinase 1; Protein Kinase, mitogen-activated, Kinase 2.	WB	Human
	MEK1 Antibody (YA5208) is a mouse-derived and non-conjugated monoclonal antibody, targeting to MEK1. It can be applicated for WB assays, in the background of human.

HY-P83405

	JNK3 Antibody (YA3150) Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; MAPK10; JNK3; JNK3A; PRKM10; SAPK1B	WB, ICC/IF, FC	Human, Mouse, Rat
	JNK3 Antibody (YA3150) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3150), targeting JNK3, with a predicted molecular weight of 53 kDa (observed band size: 53 kDa). JNK3 Antibody (YA3150) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.

HY-P83774

	Phospho-MAPKAPK2 (Thr334) Antibody MAPKAPK2; MAP Kinase-activated protein Kinase 2; MAPK-activated protein Kinase 2; MAPKAP Kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2		Human, Mouse, Rat
	Phospho-MAPKAPK2 (Thr334) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-MAPKAPK2 (Thr334).

HY-P87386

	p38 beta/MAPK11 + p38 gamma/MAPK12 + p38 delta/MAPK13 Antibody (YA7069) ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracellular signal-regulated Kinase 6 antibody; MAP Kinase 12 antibody; MAP Kinase p38 gamma antibody; MAPK 12 antibody; MAPK12 antibody; Mitogen Activated Protein Kinase 12 antibody; Mitogen activated protein Kinase p38 gamma antibody	WB	Human, Mouse, Rat, Monkey

HY-P87165

	p38 gamma/MAPK12 Antibody (YA6858) ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracellular signal-regulated Kinase 6 antibody; MAP Kinase 12 antibody; MAP Kinase p38 gamma antibody; MAPK 12 antibody; MAPK12 antibody; Mitogen Activated Protein Kinase 12 antibody; Mitogen activated protein Kinase p38 gamma antibody; ERK 6 antibody; ERK-6 antibody; ERK6 antibody; Extracellular signal-regulated Kinase 6 antibody; MAP Kinase 12 antibody; MAP Kinase p38 gamma antibody; MAPK 12 antibody; MAPK12 antibody; Mitogen Activated Protein Kinase 12 antibody; Mitogen activated protein Kinase p38 gamma antibody; Mitogen-activated protein Kinase 12 antibody; Mitogen-activated protein Kinase p38 gamma antibody; MK12_HUMAN antibody; P38 GAMMA antibody; P38GAMMA antibody; PRKM12 antibody; SAPK 3 antibody; SAPK-3 antibody; SAPK3 antibody; Stress Activated Protein Kinase 3 antibody; Stress-activated protein Kinase 3 antibody;	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	p38 gamma/MAPK12 Antibody (YA6858) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p38 gamma/MAPK12.

HY-P82902

	MEK7 Antibody (YA2647) MAP2K7; JNKK2; MEK7; MKK7; PRKMK7; SKK4; Dual specificity mitogen-activated protein Kinase Kinase 7; MAP Kinase Kinase 7; MAPKK 7; JNK-activating Kinase 2; MAPK/ERK Kinase 7; MEK 7; Stress-activated protein Kinase Kinase 4; SAPK Kinase 4; S	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	MEK7 Antibody (YA2647) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK7.

HY-P83314

	MEK2 Antibody (YA3059) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein Kinase Kinase 2; MAP Kinase Kinase 2; MAPKK 2; ERK activator Kinase 2; MAPK/ERK Kinase 2; MEK 2	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse
	MEK2 Antibody (YA3059) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3059), targeting MEK2, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). MEK2 Antibody (YA3059) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

HY-P85274

	MEK2 Antibody (YA4966) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein Kinase Kinase 2; MAP Kinase Kinase 2; MAPKK 2; ERK activator Kinase 2; MAPK/ERK Kinase 2; MEK 2	WB, ICC/IF, FC, ELISA	Human, Mouse, Rat
	MEK2 Antibody (YA4966) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MEK2.

HY-P85739

	MEK2 Antibody (YA5431) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein Kinase Kinase 2; MAP Kinase Kinase 2; MAPKK 2; ERK activator Kinase 2; MAPK/ERK Kinase 2; MEK 2	WB	Human, Rat, Mouse
	MEK2 Antibody (YA5431) is a mouse-derived and non-conjugated monoclonal antibody, targeting to MEK2. It can be applicated for WB assays, in the background of human, rat, mouse.

HY-P86470

	MEK1 Antibody (YA6162) MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein Kinase Kinase 1; MAP Kinase Kinase 1; MAPKK 1; MKK1; ERK activator Kinase 1; MAPK/ERK Kinase 1; MEK 1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MEK1 Antibody (YA6162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK1.

HY-P86251

	JNK1/2/3 Antibody (YA5943) MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein Kinase 8; MAP Kinase 8; MAPK 8; JNK-46; Stress-activated protein Kinase 1c; SAPK1c; Stress-activated protein Kinase JNK1; c-Jun N-terminal Kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	JNK1/2/3 Antibody (YA5943) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to JNK1/2/3.

HY-P85311

	p38β Antibody (YA5003) MAPK11; PRKM11; SAPK2; SAPK2B; Mitogen-activated protein Kinase 11; MAP Kinase 11; MAPK 11; Mitogen-activated protein Kinase p38 beta; MAP Kinase p38 beta; p38b; Stress-activated protein Kinase 2b; SAPK2b; p38-2	WB, ELISA	Human
	p38β Antibody (YA5003) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to p38β.

HY-P81343

	MAP2K6 Antibody (YA1088) MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein Kinase Kinase 6; MAP Kinase Kinase 6; MAPKK 6; MAPK/ERK Kinase 6; MEK 6; Stress-activated protein Kinase Kinase 3; SAPK Kinase 3; SAPKK-3; SAPKK3	WB, IP	Human, Rat
	MAP2K6 Antibody (YA1088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MAP2K6.

HY-P85276

	MAP2K6 Antibody (YA4968) MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein Kinase Kinase 6; MAP Kinase Kinase 6; MAPKK 6; MAPK/ERK Kinase 6; MEK 6; Stress-activated protein Kinase Kinase 3; SAPK Kinase 3; SAPKK-3; SAPKK3	WB, ICC/IF, FC, ELISA	Human, Mouse
	MAP2K6 Antibody (YA4968) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MAP2K6.

HY-P86356

	MEK3 Antibody (YA6048) MAP2K3; MEK3; MKK3; PRKMK3; SKK2; Dual specificity mitogen-activated protein Kinase Kinase 3; MAP Kinase Kinase 3; MAPKK 3; MAPK/ERK Kinase 3; MEK 3; Stress-activated protein Kinase Kinase 2; SAPK Kinase 2; SAPKK-2; SAPKK2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MEK3 Antibody (YA6048) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK3.

HY-P83395

	MEK5 Antibody (YA3140) MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein Kinase Kinase 5; MAP Kinase Kinase 5; MAPKK 5; MAPK/ERK Kinase 5; MEK 5	WB, ICC/IF	Human
	MEK5 Antibody (YA3140) is a non-conjugated IgG antibody, targeting MEK5, with a predicted molecular weight of 50 kDa. MEK5 Antibody (YA3140) can be used for WB, ICC/IF experiment in human background.

HY-P85333

	MAPKAPK5 Antibody (YA5025) MAPKAPK5; PRAK; MAP Kinase-activated protein Kinase 5; MAPK-activated protein Kinase 5; MAPKAP Kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein Kinase; PRAK	WB, IHC-P, ICC/IF, ELISA	Human
	MAPKAPK5 Antibody (YA5025) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MAPKAPK5.

HY-P85712

	p38 alpha/MAPK14 Antibody (YA5404) Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein Kinase p38 alpha; MAP Kinase p38 alpha; Stress-activated protein Kinase 2a; SAPK2a;	WB, ICC/IF, ELISA	Human, Mouse, Rat
	p38 alpha/MAPK14 Antibody (YA5404) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p38 alpha/MAPK14.

HY-P86460

	p38 alpha/MAPK14 Antibody (YA6152) Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein Kinase p38 alpha; MAP Kinase p38 alpha; Stress-activated protein Kinase 2a; SAPK2a;	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	p38 alpha/MAPK14 Antibody (YA6152) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p38 alpha/MAPK14.

HY-P80832

	Phospho-MEK1 (Ser298) Antibody (YA178) 1 Publications Verification MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein Kinase Kinase 1; MAP Kinase Kinase 1; MAPKK 1; MKK1; ERK activator Kinase 1; MAPK/ERK Kinase 1; MEK 1	WB, ICC/IF	Human, Mouse, Rat
	Phospho-MEK1 (Ser298) Antibody (YA178) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-MEK1 (Ser298).

HY-P80833

	Phospho-MEK1 (Thr292) Antibody (YA177) MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein Kinase Kinase 1; MAP Kinase Kinase 1; MAPKK 1; MKK1; ERK activator Kinase 1; MAPK/ERK Kinase 1; MEK 1	WB	Mouse, Rat
	Phospho-MEK1 (Thr292) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Thr292). It can be used for WB assays with tag free, in the background of Mouse, Rat.

HY-P86863

	ERK8 Antibody (YA6556) ERK 7 antibody; ERK 8 antibody; ERK-7 antibody; ERK-8 antibody; ERK7 antibody; ERK8 antibody; Extracellular regulated Kinase 8 delta antibody; Extracellular signal regulated Kinase 8 antibody; Extracellular signal-regulated Kinase 7 antibody; Extracellular signal-regulated Kinase 8 antibody; ERK 7 antibody; ERK 8 antibody; ERK-7 antibody; ERK-8 antibody; ERK7 antibody; ERK8 antibody; Extracellular regulated Kinase 8 delta antibody; Extracellular signal regulated Kinase 8 antibody; Extracellular signal-regulated Kinase 7 antibody; Extracellular signal-regulated Kinase 8 antibody; MAP Kinase 15 antibody; MAPK 15 antibody; MAPK15 antibody; Mitogen activated protein Kinase 15 antibody; Mitogen-activated protein Kinase 15 antibody; MK15_HUMAN antibody	WB, IHC-P	Human, Mouse, Rat

HY-P85275

	MEK4 Antibody (YA4967) MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein Kinase Kinase 4; MAP Kinase Kinase 4; MAPKK 4; JNK-activating Kinase 1; MAPK/ERK Kinase 4; MEK 4; SAPK/ERK Kinase 1; SEK1; Stress-activated pro	WB, IHC-P, ICC/IF, FC, ELISA	Human
	MEK4 Antibody (YA4967) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MEK4.

HY-P86344

	MEK4 Antibody (YA6036) MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein Kinase Kinase 4; MAP Kinase Kinase 4; MAPKK 4; JNK-activating Kinase 1; MAPK/ERK Kinase 4; MEK 4; SAPK/ERK Kinase 1; SEK1; Stress-activated pro	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MEK4 Antibody (YA6036) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MEK4.

HY-P80776

	p38 alpha/MAPK14 Antibody (YA696) 2 Publications Verification MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein	WB	Human, Mouse, Rat, Monkey
	p38 alpha/MAPK14 Antibody (YA696) (YA696) is a non-conjugated and Mouse origined monoclonal antibody about 41 kDa, targeting to p38 (5A1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80777

	p38 alpha/MAPK14 Antibody (YA252) MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein	WB, IP	Human
	p38 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to p38. It can be used for WB,IP assays with tag free, in the background of Human.