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Results for "

HSV

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HSV (209) Acyltransferase (2) Adenosine Receptor (11) Akt (2) Androgen Receptor (1) Antibiotic (35) AP-1 (1) Apoptosis (31) ATP Synthase (1) Autophagy (18) Bacterial (38) Biochemical Assay Reagents (3) Caspase (2) Cathepsin (2) CCR (1) CDK (4) Cholinesterase (ChE) (1) CMV (22) COX (2) CXCR (1) Cyclic GMP-AMP Synthase (1) Cytochrome P450 (1) DNA/RNA Synthesis (21) Drug Metabolite (2) DYRK (1) EBV (1) Endogenous Metabolite (48) Enterovirus (3) ERK (1) FAK (1) Ferroptosis (4) FGFR (2) Filovirus (1) Flavivirus (2) Fungal (9) GSK-3 (2) HBV (5) HCV (1) HIF/HIF Prolyl-Hydroxylase (1) Histone Demethylase (3) HIV (17) HPV (2) HSP (1) Influenza Virus (10) Integrin (2) Interleukin Related (3) Isotope-Labeled Compounds (30) Mitophagy (2) MMP (1) Monoamine Oxidase (2) NF-κB (2) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (25) Orthopoxvirus (10) Parasite (10) Phosphatase (2) Proton Pump (2) Reactive Oxygen Species (ROS) (6) Reference Standards (37) RSV (2) S100 Protein (2) SARS-CoV (4) SGLT (1) STAT (5) STING (2) Tau Protein (2) Thymidylate Synthase (3) Toll-like Receptor (TLR) (2) Tyrosinase (2) VEGFR (1) Virus Protease (5) VSV (5) YB-1 (1)
By Research Areas:	Cancer (75) Cardiovascular Disease (1) Infection (218) Inflammation/Immunology (32) Metabolic Disease (33) Neurological Disease (10)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Nucleosides and their Analogs (4) C (1) U (1) G (2) Cholesterol (1)

234

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: HSV

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1862

HSV-gB2 (498-505)	HSV	Infection
HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope .

HY-174252

HSV-1/HSV-2-IN-3	HSV	Infection
HSV-1/HSV-2-IN-3 inhibits the herpes-simplex-virus (HSV) helicase-primase complex, blocking the coordinated DNA-unwinding and primer-synthesis steps required for viral genome replication. HSV-1/HSV-2-IN-3 exhibits an EC₅₀ of 7.0 nM against HSV-2 in a gD-immunofluorescence cell assay containing 2 % FBS and 57.5 nM when 10 % human serum is present. HSV-1/HSV-2-IN-3 achieves an EC₅₀ of 1.1 nM in a qPCR replication assay. HSV-1/HSV-2-IN-3 shows strong selectivity over human carbonic-anhydrase off-targets (IC₅₀ ≈ 2.9 µM for hCA II and > 35 µM for hCA I). HSV-1/HSV-2-IN-3 can be studied in anti-HSV research .

HY-163546

HSV-1-IN-1	HSV	Infection
HSV-1-IN-1 (compound 1b) is a drug candidate for herpes simplex virus *HSV-1(IC₅₀*=0.5 nM) and *HSV-2(IC₅₀*=16 nM) infection. HSV-1-IN-1 inhibits the helicase-primase complex to prevent viral replication, thereby inhibiting *HSV* infection .

HY-149023

HSV-1/HSV-2-IN-2	HSV	Infection
HSV-1/HSV-2-IN-2 is a *HSV-1, HSV-2* and VV inhibitor with EC₅₀ values of 6.8, 8.9 and 8.9 µM, respectively. HSV-1/HSV-2-IN-2 shows antiviral activity .

HY-149022

HSV-1/HSV-2-IN-1	HSV Orthopoxvirus	Infection
HSV-1/HSV-2-IN-1 (compound 7d) is a *HSV-1* and *HSV-2* inhibitor, with EC₅₀s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK ^- KOS ACV ^r and vaccinia virus in human embryonic lung fibroblast cell cultures .

HY-126218

HSV-TK substrate	HSV	Cancer
HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity .

HY-174429

HSV-1-IN-3	HSV	Infection
HSV-1-IN-3 (Compound A50) is a *HSV* inhibitor. HSV-1-IN-3 shows good antiviral efficacy against both Acyclovir (HY-17422) -sensitive and -resistant HSV strains .

HY-176163

HSV-1-IN-2	HSV	Infection
HSV-1-IN-2 (compound 5i) is a potent Herpes simplex virus type 1 (HSV-1) inhibitor with an EC₅₀ of 1.95 μM. HSV-1-IN-2 inhibits apoptosis and improves herpes encephalitis model mouse survival .

HY-160222

HSV-60mer sodium	HSV STING	Infection Inflammation/Immunology
HSV-60mer sodium is a 60 bp double-stranded oligonucleotide containing viral DNA motifs that derive from the herpes simplex virus 1 (HSV-1) genome . Transfected HSV-60 has been shown to potently induce IFN-β in a Toll-like receptor (TLR)-, DNA-dependent activator of IRFs (DAI)-, and RNA polymerase III (Pol III)-independent, but STING-, TBK1- and IFN regulatory factor 3 (IRF3)-dependent manner.

HY-P4773

HSV-1 Protease substrate	HSV	Infection
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (k_cat/K_m) at pH 7.5 for cleavage is 5.2 M ^-1 s ^-1 .

HY-150306

Adibelivir IM-250	HSV	Infection
Adibelivir (IM-250) is an orally active helicase-primase inhibitor. Adibelivir is effective against *HSV* infection and reduces reactivation of latent HSV. Adibelivir inhibits HSV-1 infection in Vero cells (IC₅₀: ~20 nM). Adibelivir can be used for the study of recurrent herpes disease^[1][2]_.

HY-129861

5'-Ethynyl-2'-deoxycytidine	HSV	Infection Cancer
5'-Ethynyl-2'-deoxycytidine is an inhibitor for *HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC* of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC₅₀ of 64.5 μg/mL .

HY-131606

Cidofovir diphosphate	HSV CMV	Infection
Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with K_i values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .

HY-131606B

Cidofovir diphosphate tri(triethylamine)	Drug Metabolite	Infection
Cidofovir diphosphate tri triethylamine is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate tri triethylamine is a selective inhibitor of viral DNA polymerases with K_i values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .

HY-N0097S5

Guanosine-d13 DL-Guanosine-d₁₃; Vernine-d₁₃	Isotope-Labeled Compounds	Infection
Guanosine-d13 (DL-Guanosine-d13) is a deuterium of Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-N0097S6

Guanosine-13C10,15N5 DL-Guanosine-¹³C₁₀,¹⁵N₅; Vernine-¹³C₁₀,¹⁵N₅	HSV Isotope-Labeled Compounds	Infection
Guanosine- ¹³C₁₀, ¹⁵N₅ is the ¹³C and ¹⁵N labeled Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-N0097S4

Guanosine-13C10 DL-Guanosine-¹³C₁₀; Vernine-¹³C₁₀	Isotope-Labeled Compounds Endogenous Metabolite HSV	Infection
Guanosine- ¹³C₁₀ is the ¹³C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-148169

2'-Deoxy-L-guanosine	Nucleoside Antimetabolite/Analog	Infection
2'-Deoxy-L-guanosine selectively inhibits D-Thymidine phosphorylation catalyzed by HSV 1 thymidine kinase. 2'-Deoxy-L-guanosine is the L-configuration of 2'-Deoxyguanosine (HY-17563) .

HY-N7346

Lucidadiol	HSV Cholinesterase (ChE)	Infection
Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC₅₀ values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1 .

HY-106892

BW 348U87 348U87	DNA/RNA Synthesis	Infection
BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model .

HY-116758

16,16-Dimethyl prostaglandin A1 di-Me-PGA1	DNA/RNA Synthesis HIV HSV	Infection Cancer
16,16-Dimethyl prostaglandin A1 (di-Me-PGA1) is a prostaglandin analog that can inhibit DNA synthesis in Lewis lung carcinoma and B 16 amelanotic melanoma cells. 16,16-Dimethyl prostaglandin A1 also inhibits viral replication in both *HSV* and HIV-1 infection systems .

HY-19333

OG-L002 1 Publications Verification	Histone Demethylase Monoamine Oxidase HSV	Infection
OG-L002 is a potent and highly selective LSD1 inhibitor with an IC₅₀ of 0.02 μM. OG-L002 is a potent monoamine oxidases (MAO) inhibitor with IC₅₀s of 1.38 μM and 0.72 μM for MAO-A and MAO-B, respectively. OG-L002 potently inhibits the expression of HSV IE genes .

HY-19333A

OG-L002 hydrochloride	Histone Demethylase Monoamine Oxidase HSV	Infection
OG-L002 hydrochloride is a potent and highly selective LSD1 inhibitor with an IC₅₀ of 0.02 μM. OG-L002 hydrochloride is a potent monoamine oxidases (MAO) inhibitor with IC₅₀s of 1.38 μM and 0.72 μM for MAO-A and MAO-B, respectively. OG-L002 hydrochloride potently inhibits the expression of HSV IE genes .

HY-W291131

Isatin-β-thiosemicarbazone IBT	HSV Orthopoxvirus	Infection
Isatin-β-thiosemicarbazone is a potent anti-poxvirus agent (including monkeypox virus, orthopoxvirus, vaccinia virus, etc). Isatin-β-thiosemicarbazone also is a potent herpes simplex virus (HSV) inhibitor. Isatin-β-thiosemicarbazone exhibits

HY-100272

B220	HSV CMV	Infection Cancer
B220 is an antiviral agent which can inhibit the growth of *HSV-1, HSV-2* and human cytomegalovirus (CMV).

HY-148852

PNU-183792	HSV	Infection
PNU-183792, a 4-oxo-dihydroquinoline, is an orally active HSV polymerases inhibitor. PNU-183792 shows a broad-spectrum antiviral activity, with IC₅₀ values of 0.69 μM, 0.37 μM and 0.58 μM for human cytomegalovirus (HCM), varicella zoster virus and HSV polymerases, respectively. PNU-183792 is inactive against human α, γ and δ polymerases. PNU-183792 also inhibits simian varicella virus (SVV), murine cytomegalovirus (MCMV) and rat cytomegalovirus (RCMV) .

HY-U00124

Tromantadine	HSV	Infection
Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .

HY-U00124B

Tromantadine hydrochloride 1 Publications Verification	HSV	Infection
Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and *HSV-2* replication .

HY-15303B

Pritelivir mesylate hydrate 5 Publications Verification AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate	HSV	Infection
Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (HSV-1 and *HSV-2) with the IC₅₀ of 0.02 μM against HSV*1-2 .

HY-15303

Pritelivir 5 Publications Verification AIC316; BAY 57-1293	HSV	Infection
Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and *HSV-2) with the IC₅₀ of 0.02 μM against HSV*1-2 .

HY-15303A

Pritelivir mesylate 5 Publications Verification AIC316 mesylate; BAY 57-1293 mesylate	HSV	Infection
Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and *HSV-2) with the IC₅₀ of 0.02 μM against HSV*1-2 .

HY-108137

Z-LVG-CHN2 2 Publications Verification	Cathepsin HSV SARS-CoV	Infection Inflammation/Immunology
Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on *HSV* whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC₅₀=190 nM) via inhibition of SARS-COV-2 3CL pro protease .

HY-N7677

Isookanin	HSV	Infection Inflammation/Immunology Cancer
Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity .

HY-W141881

N-Lauroylsarcosine	Biochemical Assay Reagents HSV	Infection
N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection .

HY-15303AR

Pritelivir mesylate (Standard)	HSV	Infection
Pritelivir (mesylate) (Standard) is the analytical standard of Pritelivir (mesylate). This product is intended for research and analytical applications. Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .

HY-15303R

Pritelivir (Standard)	HSV	Infection
Pritelivir (Standard) is the analytical standard of Pritelivir. This product is intended for research and analytical applications. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .

HY-118745

A-73209	HSV	Infection
A-73209 is an orally active and potent antivirus agent against VZV, HSV-1, and HSV-2. A-73209 is an Oxetanocin derivative and can be utilized in antivirus research .

HY-A0181A

Adenosine 5'-monophosphate monohydrate 10+ Cited Publications 5'-AMP monohydrate	Endogenous Metabolite Adenosine Receptor HSV	Infection Metabolic Disease
Adenosine 5'-monophosphate monohydrate is an adenosine A₁ receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against *HSV-1* and *HSV-2* .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits *HSV-1/2* virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-15303S

Pritelivir-d4-1 AIC316-d4-1; BAY 57-1293-d4-1	Isotope-Labeled Compounds HSV	Infection
Pritelivir-d₄-1 (AIC316-d₄-1) is deuterium labeled Pritelivir. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and *HSV-2) with the IC₅₀ of 0.02 μM against HSV*1-2 .

HY-N14446

Karalicin	HSV	Infection
Karalicin inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC₅₀s (μg/mL) of 0.004, 0.008, 0.016 and 0.016 .

HY-108137A

Z-L(D-Val)G-CHN2	Cathepsin HSV SARS-CoV	Infection
Z-L(D-Val)G-CHN2 is the isoform of Z-LVG-CHN2 (HY-108137). Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on *HSV* whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC₅₀=190 nM) via inhibition of SARS-COV-2 3CL pro protease .

HY-107801

Inosine pranobex 1 Publications Verification Imunovir; Delimmun; Groprinosin	Interleukin Related HSV HIV HPV	Infection Inflammation/Immunology
Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus .

HY-A0181

Adenosine monophosphate 10+ Cited Publications AMP	Endogenous Metabolite Adenosine Receptor HSV	Infection Metabolic Disease
Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-170547

DNA polymerase-IN-6	DNA/RNA Synthesis HSV Filovirus	Infection
DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, and inhibits HCMV, *HSV-1, HSV-2* and EBV with EC₅₀s of 0.33, 1.9, 0.76 and 0.066 µM, respectively .

HY-50735

Fiacitabine NSC 382097; FIAC; FOAC	HSV	Infection
Fiacitabine(NSC 382097; FIAC; FOAC) is a selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively.

HY-107739

Penciclovir sodium VSA 671 sodium; BRL 39123A; BRL 39123D	HSV	Infection
Penciclovir (VSA 671) sodium is a potent and selective anti-herpesvirus agent with EC₅₀ values of 0.5, 0.8 µg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir sodium shows anti-herpesvirus activity with no-toxic. Penciclovir sodium preventes mortality in mouse .

HY-17424

Penciclovir 1 Publications Verification BRL 39123; VSA 671	HSV	Infection
Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC₅₀ values of 0.5, 0.8 μg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse .

HY-U00224

BRL44385	EBV HSV	Infection
BRL44385 is a potent and selective inhibitor of the replication of herpes simplex virus types 1 and 2 (HSV-1 and *HSV2*), varicella zoster virus (VZV) and Epstein-Barr virus (EBV).

HY-B0277

Vidarabine 5 Publications Verification Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine	HSV Nucleoside Antimetabolite/Analog Orthopoxvirus Antibiotic	Infection
Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses . Vidarabine has IC₅₀s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 . Vidarabine also has anti-orthopoxvirus activity .

Cat. No.	Product Name

HY-L027

Antiviral Compound Library

1,422 compounds

Viruses are much simpler organisms than bacteria, and they are made from protein substances and nucleic acid. Despite the fact that the exact mechanism of infection is extremely specific to each type of virus, the general scheme of infection can be represented in the following manner: A virus is absorbed at the surface of a host cell and then permeates through the membrane, where it releases nucleic acid from its protein protection. Then the viral nucleic acid begins to replicate, and transcription of the viral genome takes place either in the cytoplasm, or in the nucleus of the host cell. As a result of these events, a large amount of viral nucleic acid and protein are made to make new generations of virions. Therefore, one mechanism of action of antiviral drugs is to interfere with the ability of a virus to get into a target cell. A second mechanism of action is to target the processes that synthesize virus components after a virus invades a cell, such as nucleotide or nucleoside analogs.

MCE designs a unique collection of 1,422 anti-virus compounds that target several viruses, including SARS-CoV, HBV, HCV, HIV, HSV and Influenza Virus. It’s an effective tool for anti-virus drug discovery.

Cat. No.	Product Name	Target	Research Area

HY-P1862

HSV-gB2 (498-505)	HSV	Infection
HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope .

HY-W141881

N-Lauroylsarcosine	Biochemical Assay Reagents HSV	Infection
N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection .

HY-P5997

XQ2B	Autophagy Cyclic GMP-AMP Synthase	Inflammation/Immunology
XQ2B is a specific cGAS inhibitor targeting protein-DNA interaction and phase separation. XQ2B markedly reduces ISD-induced Autophagy. XQ2B inhibits herpes simplex virus 1 (HSV-1)-induced antiviral immune responses and enhances HSV-1 infection .

HY-P1958

Histone H4 (2-21)	HSV	Infection
Histone H4 (2-21) is the core histones associated with chromatinization of herpes simplex virus 1 (HSV-1) genomes .

HY-P4773

HSV-1 Protease substrate	HSV	Infection
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (k_cat/K_m) at pH 7.5 for cleavage is 5.2 M ^-1 s ^-1 .

HY-P5567

GLR-19	HIV HSV	Infection
GLR-19 is an anti-HIV peptide. GLR-19 also has antiviral activity against *HSV-2* .

HY-P5693

HBA(111–142)	Bacterial CMV HSV	Infection
HBA(111-142), an antimicrobial peptide, is a C-terminal 32-mer fragment of alpha-hemoglobin. HBA(111-142) has antibacterial activity against the ESKAPE panel of pathogens. HBA(111-142) forms amyloid fibrils, and has antiviral activities. HBA(111-142) inhibits measles and herpes viruses (HSV-1, HSV-2, HCMV) .

HY-P2036

FSL-1	Toll-like Receptor (TLR) Antibiotic	Infection
FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection .

HY-P4318

HHV-2 Envelope Glycoprotein G (552-574)	HSV	Infection
HHV-2 Envelope Glycoprotein G (552-574) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .

HY-P4743

FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)	HSV	Infection
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578) is a FITC labeled HHV-2 Envelope Glycoprotein G (561-578). HHV-2 Envelope Glycoprotein G (561-578) is an immunodominant region of glycoprotein G (gG-2) reactive with all herpes simplex (HSV-2) sera .

HY-P2036A

FSL-1 TFA 3 Publications Verification	Toll-like Receptor (TLR) MMP HSV Antibiotic	Infection
FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection . FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB/AP-1 signaling pathways in monocytic THP-1 cells .

HY-14743

Golotimod SCV 07; Gamma-D-glutamyl-L-tryptophan	Bacterial STAT	Infection Inflammation/Immunology Cancer
Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .

HY-P11008

DX-236	Biochemical Assay Reagents	Others
DX-236 is a macrocyclic peptide with a binding affinity of 1.9 µM to human serum albumin (HSA). DX-236 can fuse with HSV to prolong its circulation in vivo.

HY-14743R

Golotimod (Standard)	Bacterial STAT	Infection Inflammation/Immunology Cancer
Golotimod (Standard) is the analytical standard of Golotimod. This product is intended for research and analytical applications. Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .

Cat. No.	Product Name	Target	Research Area

HY-P991072

MB-66 MAPP-66	HIV HSV	Infection
MB-66 (MAPP-66) is a fully human IgG1 antibody that targets *HSV* and HIV. MB-66 is a monoclonal antibody film for vaginal application. The isotype control for MB-66 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7346

Lucidadiol	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	HSV Cholinesterase (ChE)
Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC₅₀ values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1 .

HY-N7677

Isookanin	Structural Classification Classification of Application Fields Source classification Plants Compositae Infection Flavonoids Deguelia rufescens (Benth.) R.A.Camargo & A.M.G.Azevedo Flavonones Phenols Polyphenols Inflammation/Immunology Disease Research Fields	HSV
Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity .

HY-A0181A

Adenosine 5'-monophosphate monohydrate 10+ Cited Publications 5'-AMP monohydrate	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Adenosine Receptor HSV
Adenosine 5'-monophosphate monohydrate is an adenosine A₁ receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against *HSV-1* and *HSV-2* .

HY-A0181

Adenosine monophosphate 10+ Cited Publications AMP	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Adenosine Receptor HSV
Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-B0277

Vidarabine 5 Publications Verification Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine	Infection Structural Classification Microorganisms Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields	HSV Nucleoside Antimetabolite/Analog Orthopoxvirus Antibiotic
Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses . Vidarabine has IC₅₀s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 . Vidarabine also has anti-orthopoxvirus activity .

HY-N1067

Xanthohumol 10+ Cited Publications	Infection Structural Classification Chalcones Flavonoids Classification of Application Fields Humulus lupulus L. Source classification Phenols Polyphenols Plants Moraceae Disease Research Fields	COX Acyltransferase Apoptosis HSV CMV Influenza Virus
Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, *HSV-1, HSV-2* and cytomegalovirus (CMV).

HY-N1430

Oxyresveratrol 1 Publications Verification trans-Oxyresveratrol	Structural Classification other families Stilbenes Classification of Application Fields Anti-aging Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Tyrosinase HSV Autophagy
Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC₅₀ of 28.9 µM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC₅₀ value of 1.2 µM for mushroom tyrosinase. Oxyresveratrol is effective against *HSV-1, HSV-2* and varicella-zoster virus, and has neuroprotective effects .

HY-N10177

Peniterphenyl A	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	HSV
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits *HSV-1/2* virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-N14446

Karalicin	Structural Classification Natural Products Microorganisms Source classification	HSV
Karalicin inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC₅₀s (μg/mL) of 0.004, 0.008, 0.016 and 0.016 .

HY-111801

Woodorien	Structural Classification Blechnaceae Source classification Plants Woodwardia orientalis Sw. Saccharides Monosaccharides	HSV
Woodorien is a potent *HSV-1* inhibitor. Woodorien also is a glucoside that can be isolated from Woodwardia orientalis .

HY-B0277R

Vidarabine (Standard) Ara-A (Standard); Adenine Arabinoside (Standard); 9-β-D-Arabinofuranosyladenine (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antiviral Antibacterial Disease Research	Reference Standards HSV Nucleoside Antimetabolite/Analog Orthopoxvirus Antibiotic
Vidarabine (Standard) is the analytical standard of Vidarabine. This product is intended for research and analytical applications. Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses . Vidarabine has IC₅₀s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 . Vidarabine also has anti-orthopoxvirus activity .

HY-A0181R

Adenosine monophosphate (Standard) AMP (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Adenosine Receptor HSV
Adenosine monophosphate (Standard) is the analytical standard of Adenosine monophosphate (HY-A0181). This product is intended for research and analytical applications. Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-122920

Soyasaponin II	Triterpenes Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields Glycine soja Sieb. Et Zucc.	HSV CMV Influenza Virus HIV NOD-like Receptor (NLR) YB-1
Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure .

HY-N1067R

Xanthohumol (Standard)	Structural Classification Chalcones Flavonoids Humulus lupulus L. Source classification Phenols Polyphenols Plants Moraceae	Reference Standards COX Acyltransferase Apoptosis HSV CMV Influenza Virus
Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).

HY-N1430R

Oxyresveratrol (Standard) trans-Oxyresveratrol (Standard)	Structural Classification other families Stilbenes Source classification Phenols Polyphenols Plants	Reference Standards Tyrosinase HSV Autophagy
Oxyresveratrol (Standard) is the analytical standard of Oxyresveratrol. This product is intended for research and analytical applications. Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 μM against DPPH free radicals). Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects .

HY-113135

5-Methylcytidine	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Nucleoside Antimetabolite/Analog HSV
5-Methylcytidine is a nucleoside compound. 5-Methylcytidine has antiviral activity, and its IC₅₀ against *HSV-1* is 0.06 μM .

HY-N14563

Cycloviracin B1	Structural Classification Natural Products Microorganisms Source classification	Bacterial HSV
Cycloviracin B1 has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-Gram-positive bacterial activity .

HY-N14564

Cycloviracin B2	Structural Classification Natural Products Microorganisms Source classification	Antibiotic HSV
Cycloviracin B2 is an antibiotic with antiviral activity. Cycloviracin B2 has a strong inhibitory activity against herpes simplex virus type 1 (HSV-1) .

HY-N1451

Betulonic acid 4 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Infection Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Parasite HSV
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N1060

Yatein	Infection Structural Classification Cupressaceae Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Disease Research Fields Chamaecyparis obtusa	HSV Apoptosis
Yatein is a lignan isolated from A. chilensis, with antiproliferative activity . Yatein suppresses *herpes simplex virus type 1 (HSV-1 )* replication by interruption the immediate-early gene expression .

HY-N2004

Isoborneol (±)-Isoborneol	Structural Classification Natural Products Source classification Curcuma aromatica Salisb. cv. Wenyujin Plants Zingiberaceae	HSV
Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 *(HSV-1)* .

HY-Y0136

3-Indoleacetonitrile 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Influenza Virus HSV VSV
3-Indoleacetonitrile is an indole derivative with anti-influenza activity. 3-Indoleacetonitrile is a plant hormone produced by cruxiferous vegetables. 3-Indoleacetonitrile exerts profound antiviral activity against a broad spectrum of influenza A viruses, HSV-1 and VSV viruses in vitro. 3-Indoleacetonitrile diminishes lung virus titers and alleviates lung lesions in vivo. 3-Indoleacetonitrile induces an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile can be used in research for combating viral infections including COVID-19, HSV-1, and VSV .

HY-N3395

Leachianone G	Flavonoids Flavonones Source classification Morus alba L. Plants Moraceae	HSV
Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC₅₀* value of 1.6 μg/mL .*

HY-17425A

Valacyclovir hydrochloride 1 Publications Verification Valaciclovir hydrochloride	Infection Classification of Application Fields Disease Research Fields	HSV Antibiotic Bacterial
Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits *HSV-1* W (₅₀=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) .

HY-N1451R

Betulonic acid (Standard) Betunolic acid (Standard); Liquidambaric acid (Standard); (+)-Betulonic acid (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Reference Standards Parasite HSV
Betulonic acid (Standard) is the analytical standard of Betulonic acid. This product is intended for research and analytical applications. Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N11097

FK-3000	Structural Classification Alkaloids Piperidine Alkaloids Source classification Plants Stephania delavayi Diels Menispermaceae	Apoptosis HSV HIV
FK-3000 is a potent anti-tumor agent that inhibits the growth of carcinoma cells through apoptosis and induction cell cycle arrest. FK-3000 also exhibit antiviral effects against *HSV-1* and HIV-1 .

HY-113135R

5-Methylcytidine (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog HSV
5-Methylcytidine (Standard) is the analytical standard of 5-Methylcytidine. This product is intended for research and analytical applications. 5-Methylcytidine is a nucleoside compound. 5-Methylcytidine has antiviral activity, and its IC₅₀ against *HSV-1* is 0.06 μM .

HY-16592

Brefeldin A Maximum Cited Publications 105 Publications Verification BFA; Cyanein; Decumbin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antiviral Disease Research Anticancer Disease Research Fields	Autophagy Mitophagy HSV Antibiotic Bacterial
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus . Brefeldin A is also an autophagy and mitophagy inhibitor . Brefeldin A inhibits *HSV-1* and has anti-cancer activity .

HY-N2004R

Isoborneol (Standard) (±)-Isoborneol (Standard)	Structural Classification Natural Products Source classification Curcuma aromatica Salisb. cv. Wenyujin Plants Zingiberaceae	Reference Standards HSV
Isoborneol (Standard) is the analytical standard of Isoborneol. This product is intended for research and analytical applications. Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1) .

HY-Y0136R

3-Indoleacetonitrile (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Influenza Virus HSV VSV
3-Indoleacetonitrile (Standard) is the analytical standard of 3-Indoleacetonitrile. This product is intended for research and analytical applications. 3-Indoleacetonitrile is an indole derivative with anti-influenza activity. 3-Indoleacetonitrile is a plant hormone produced by cruxiferous vegetables. 3-Indoleacetonitrile exerts profound antiviral activity against a broad spectrum of influenza A viruses, HSV-1 and VSV viruses in vitro. 3-Indoleacetonitrile diminishes lung virus titers and alleviates lung lesions in vivo. 3-Indoleacetonitrile induces an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile can be used in research for combating viral infections including COVID-19, HSV-1, and VSV .

HY-N2011

Octyl gallate n-Octyl gallate; Stabilizer GA 8	Infection Structural Classification Paeonia lactiflora Pall. Classification of Application Fields Source classification Phenols Polyphenols Plants Paeoniaceae Disease Research Fields	VSV Bacterial HSV Influenza Virus Reactive Oxygen Species (ROS)
Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against *HSV-1, vesicular stomatitis virus (VSV)* and poliovirus .

HY-110398

5,6,7-Trimethoxyflavone Baicalein trimethyl ether	Structural Classification Flavonoids Classification of Application Fields Flavones Verbenaceae Bignoniaceae Plants Oroxylum indicum (Linn.) Bentham ex Kurz Callicarpa japonica Thunb. Inflammation/Immunology Disease Research Fields Cancer	NF-κB AP-1 STAT HSV CMV Enterovirus
5,6,7-Trimethoxyflavone is a flavonoid compound that can be isolated from plants Callicarpa japonica. 5,6,7-Trimethoxyflavone exhibits antiviral and anti-inflammatory activities through inhibition of NF-κB/AP-1/STAT signaling pathway .

HY-107789

Sodium lauryl sulfoacetate	Structural Classification Saururaceae Classification of Application Fields Houttuynia cordata Thunb. Ketones, Aldehydes, Acids Source classification Plants Inflammation/Immunology Disease Research Fields	Biochemical Assay Reagents HSV
Sodium lauryl sulfoacetate is a solid anionic surfactant of plant origin. Sodium lauryl sulfoacetate is an immunoadjuvant with antiimmunosuppressive effects. Sodium lauryl sulfoacetate has antiviral activity .

HY-16592R

Brefeldin A (Standard) BFA (Standard); Cyanein (Standard); Decumbin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antiviral Disease Research Anticancer	Reference Standards Autophagy Mitophagy HSV Antibiotic Bacterial
Brefeldin A (Standard) (BFA (Standard)) is the analytical standard of Rutin. This product is intended for research and analytical applications. Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A inhibits HSV-1 and has anti-cancer activity.

HY-N8156

Soyasapogenol C	Infection Triterpenes Structural Classification Trifolium repens Linn. Classification of Application Fields Leguminosae Terpenoids Source classification Plants Disease Research Fields	HSV
Soyasapogenol C is an oleanane-type triterpenoid. Soyasapogenol C exhibits anti-HSV-1 activity, with an IC₅₀ of 18.9 μM .

HY-117010

Kushenol K	Flavanonols Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Plants Sophora flavescens Aiton Disease Research Fields	Cytochrome P450 HSV SGLT
Kushenol K, a flavonoid antioxidant isolated from the roots of Sophora flavescens. Kushenol K is a cytochrome P-450 3A4 (CYP3A4) inhibitor with a K_i value of 1.35 μM . Kushenol K shows weak antiviral activity against *HSV-2* (EC₅₀ of 147 μM) . Kushenol K also inhibits the activity of SGLT1 and SGLT2 .

HY-N2011R

Octyl gallate (Standard) n-Octyl gallate (Standard); Stabilizer GA 8 (Standard)	Structural Classification Paeonia lactiflora Pall. Source classification Phenols Polyphenols Plants Paeoniaceae	VSV Reference Standards Bacterial HSV Influenza Virus Reactive Oxygen Species (ROS)
Octyl gallate (Standard) is the analytical standard of Octyl gallate. This product is intended for research and analytical applications. Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .

HY-117025A

Manzamine A hydrochloride 1 Publications Verification Keramamine A hydrochloride	Structural Classification Neurological Disease Classification of Application Fields Source classification Marine natural products Pyridine Alkaloids Indole Alkaloids Infection Alkaloids Piperidine Alkaloids Animals Sponge Disease Research Fields	GSK-3 CDK Parasite Proton Pump HSV Autophagy
Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC₅₀s of 10.2 μM and 1.5 μM, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against *HSV-1* .

HY-117025

Manzamine A 1 Publications Verification Keramamine A	Infection Alkaloids Structural Classification Neurological Disease Classification of Application Fields Animals Marine natural products Sponge Disease Research Fields Cancer	GSK-3 CDK Parasite Proton Pump HSV Autophagy
Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC₅₀s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against *HSV-1* .

HY-113289

Brassicasterol	Infection Animals Classification of Application Fields Source classification Disease Research Fields Steroids Cancer	Akt Androgen Receptor Bacterial Drug Metabolite HSV
Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits *HSV-1* (IC₅₀=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease .

HY-B0222

1-Docosanol 1 Publications Verification Behenyl alcohol	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	HSV
1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) .

HY-N15215

Antiviral agent 64	Structural Classification Monophenols Source classification Phenols Alpinia officinarum Hance Plants Zingiberaceae	Enterovirus Influenza Virus RSV HSV
Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC₅₀ of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits RSV, poliovirus, measles virus, *HSV-1, and influenza virus H1N1, with EC₅₀* of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively .

HY-N12191

Cangorinine E-1	Structural Classification Alkaloids Terpenoids Other Alkaloids Sesquiterpenes Source classification Celastraceae Plants Tripterygium wilfordii Hook. f.	HSV
Cangorinine E-1 (compound 11) is a dihydroagarofuran derivative of the sesquiterpenoid family. Cangorinine E-1 exhibits weak inhibitory effects on herpes simplex virus type II (HSV) .

HY-N0097

Guanosine 5+ Cited Publications DL-Guanosine; Vernine	Structural Classification Natural Products Classification of Application Fields Anti-aging Source classification Endocrine diseases Endogenous metabolite Infection Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Disease Research Fields	HSV Endogenous Metabolite
Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.

HY-N2812

Epipodophyllotoxin acetate 4-O-Epipodophyllotoxinyl acetate	Structural Classification Cupressaceae Source classification Lignans Phenylpropanoids Plants	HSV VSV
Epipodophyllotoxin acetate (4-O-Epipodophyllotoxinyl acetate; compound 4) is a cyclolignan that exhibits antineoplastic and antiviral activities. Epipodophyllotoxin acetate inhibits *HSV* and VSV, with IC₅₀s of 0.2 and 0.1 μg/mL, respectively .

HY-N6073

Soyasapogenol A	Triterpenes Structural Classification Classification of Application Fields Leguminosae Glycine max (L.) merr Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Apoptosis HSV
Soyasapogenol A is a triterpenoid aglycone of soyasaponins. Soyasapogenol A has activities such as anti-inflammation, anti-cancer, hepatoprotection and anti-HSV-1. Soyasapogenol A can be used in the research of tumors and immune inflammatory diseases .

HY-13605

Cytarabine 70+ Cited Publications Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Marine natural products Source classification Sponge Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HSV Autophagy Apoptosis Endogenous Metabolite Orthopoxvirus
Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC₅₀ of 16 nM. Cytarabine has antiviral effects against *HSV*. Cytarabine shows anti-orthopoxvirus activity.

HY-111243

Ganoderone A	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	HSV
Ganoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against *HSV* with IC₅₀ value of 0.3 µg/mL. Ganoderone A has potential applications in viral infections and tumors .

HY-W017522

Adipic acid Hexanedioic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Cancer	Endogenous Metabolite HSV
Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-B0222R

1-Docosanol (Standard) Behenyl alcohol (Standard)	Structural Classification Natural Products other families Source classification Plants	Reference Standards HSV
1-Docosanol (Standard) is the analytical standard of 1-Docosanol. This product is intended for research and analytical applications. 1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) .

Species:	Virus (2)
Tag:	His (2)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P704068

	*glycoprotein D/gD Protein, HSV-1 (HEK293, His)* Envelope Glycoprotein D,Human alphaherpesvirus 1,HSV-1	Virus	HEK293
	glycoprotein D/gD Protein, HSV-1 (HEK293, His) is the recombinant virus-derived glycoprotein D/gD protein, expressed by HEK293, with C-6*His tag.

HY-P703871

	*glycoprotein D/gD Protein, HSV-2 (HEK293, His)* Envelope glycoprotein D; Gd; US6	Virus	HEK293
	glycoprotein D/gD Protein, HSV-2 (HEK293, His) is the recombinant virus-derived glycoprotein D/gD protein, expressed by HEK293, with C-His tag.

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Cat. No.	Product Name	Chemical Structure

HY-N0097S5

Guanosine-d13
Guanosine-d13 (DL-Guanosine-d13) is a deuterium of Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-N0097S6

Guanosine-13C10,15N5
Guanosine- ¹³C₁₀, ¹⁵N₅ is the ¹³C and ¹⁵N labeled Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-N0097S4

Guanosine-13C10
Guanosine- ¹³C₁₀ is the ¹³C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-A0181S1

Adenosine monophosphate-15N5 dilithium
Adenosine monophosphate- ¹⁵N₅ dilithium is the ¹⁵N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181S3

Adenosine monophosphate-13C10 dilithium
Adenosine monophosphate- ¹³C₁₀ (AMP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181BS

Adenosine monophosphate-13C10,15N5 disodium

1 Publications Verification

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅ (AMP- ¹³C₁₀, ¹⁵N₅) disodium is ¹³C and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181S

Adenosine monophosphate-13C10,15N5 dilithium

1 Publications Verification

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅(AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C-labeled and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-15303S

Pritelivir-d4-1
Pritelivir-d₄-1 (AIC316-d₄-1) is deuterium labeled Pritelivir. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and *HSV-2) with the IC₅₀ of 0.02 μM against HSV*1-2 .

HY-A0181S2

Adenosine monophosphate-d12 dilithium
Adenosine monophosphate-d₁₂ (AMP-d₁₂) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181S6

Adenosine monophosphate3C10,15N5

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅ (AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C- and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181S5

Adenosine monophosphate-15N5,d12 dilithium

Adenosine monophosphate- ¹⁵N₅,d₁₂ (AMP- ¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-17422S1

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC₅₀ of 0.85 μM), HSV-2 (IC₅₀ of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination . Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .

HY-A0181S4

Adenosine monophosphate-13C10,15N5,d12 dilithium

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅,d₁₂ (AMP- ¹³C₁₀, ¹⁵N₅,d₁₂) dilithium is ¹³C and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-17425AS

Valacyclovir-d8 hydrochloride
Valacyclovir-d₈ (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) .

HY-17425AS1

Valacyclovir-d4 hydrochloride
Valacyclovir-d₄ (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) .

HY-13666S

Levamisole-d5 hydrochloride
Levamisole-d₅ (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV .

HY-N0415S

Trigonelline-d3 chloride
Trigonelline-d₃ (chloride) is the deuterium labeled Trigonelline chloride. Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. Trigonelline chloride has anti-HSV-1 , antibacterial, and antifungal activities.

HY-17424S

Penciclovir-d4
Penciclovir-d₄ is the deuterium labeled Penciclovir. Penciclovir is reported to be potent against HSV types 1 and 2 with IC₅₀ of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively .

HY-13605S

Cytarabine-d2
Cytarabine-d₂ is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC₅₀ of 16 nM. Cytarabine has antiviral effects against HSV .

HY-N0097S3

Guanosine-15N5
Guanosine- ¹⁵N₅ is the ¹⁵N labeled Guanosine . Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .

HY-17426S1

Famciclovir-d6
Famciclovir-d₆ (BRL 42810-d₆) is deuterium labeled Famciclovir. Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection .

HY-N0097S1

Guanosine-8-d-1
Guanosine-8-d-1 is the deuterium labeled Guanosine. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activ .

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine . Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity .

HY-B0275S

Oxytetracycline-d6
Oxytetracycline-d₆ is deuterium labeled Oxytetracycline. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

HY-W017522S3

Adipic acid-13C
Adipic acid- ¹³C (Hexanedioic acid- ¹³C) is the ¹³C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W755036

Oxytetracycline-13C,d3 hydrochloride

Oxytetracycline-13C,d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride (HY-B0275A). Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity .

HY-W017522S

Adipic acid-d10
Adipic acid-d₁₀ (Hexanedioic acid-d₁₀) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S6

Adipic acid-13C2
Adipic acid- ¹³C₂ (Hexanedioic acid- ¹³C₂) is ¹³C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S2

Adipic acid-d4
Adipic acid-d₄ (Hexanedioic acid-d₄) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S1

Adipic acid-13C6
Adipic acid- ¹³C₆ (Hexanedioic acid- ¹³C₆) is the ¹³C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S4

Adipic acid-d8
Adipic acid-d₈ (Hexanedioic acid-d₈) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S5

Adipic acid-d4-1
Adipic acid-d₄-1 (Hexanedioic acid-d₄-1) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-13637S

Ganciclovir-d5

Ganciclovir-d₅ is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) .

HY-W766548

Floxuridine-13C,15N2

Floxuridine- ¹³C, ¹⁵N₂ (5-Fluorouracil 2'-deoxyriboside- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled labeled Floxuridine (HY-B0097). Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis . Floxuridine has antiviral effects against HSV and CMV .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81032

	HSV Tag Antibody (YA878) QPELAPEDPED tag	WB	Species independent
	HSV Tag Antibody (YA878) is an unconjugated, mouse-derived, anti-HSV Tag (YA878) monoclonal antibody. HSV Tag Antibody (YA878) can be used for: WB expriments in species-independent background without labeling.