Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) 

Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) is an Armenian Hamster-derived IgG antibody inhibitor, targeting to mouse TCR V gamma 2. Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) reacts with an epitope on the delta chain of the mouse Vγ2 TCR (V gamma 2 T cell receptor). Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) can deplete γδ T cell. Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) can be used for the researches of infection and immunology, such as herpes simplex virus-1 (HSV-1) infection^[1][2].

Armenian Hamster IgG

Polyclonal Armenian hamster IgG, Isotype Control

Mouse

Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) (500 μg at day 2 before infection and 250 μg at day of infection) depletes γδ T cell and reduces IL-17 production in herpes simplex virus-1 (HSV-1) infected C57BL/6 mice^[1].
Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6) (200 μg, i.p.) depletes γδ T cell in CFA-immunized mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA, FACS, Functional assay, Research in vivo

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

[Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6)]

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Suryawanshi A, et al. Role of IL-17 and Th17 cells in herpes simplex virus-induced corneal immunopathology. J Immunol. 2011 Aug 15;187(4):1919-30.  [Content Brief]

  [2]. Rezende RM, et al. γδ T cells control humoral immune response by inducing T follicular helper cell differentiation. Nat Commun. 2018 Aug 8;9(1):3151.  [Content Brief]