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C9

" in MedChemExpress (MCE) Product Catalog:

218

Inhibitors & Agonists

3

Fluorescent Dye

3

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1

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3

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24

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21

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67

Isotope-Labeled Compounds

12

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1

Click Chemistry

14

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N11222

    C9 carnitine

    Endogenous Metabolite Cardiovascular Disease Cancer
    Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction .
    Nonanoylcarnitine
  • HY-RS17317

    Small Interfering RNA (siRNA) Others

    C9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for C9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C9 Mouse Pre-designed siRNA Set A
    C9 Mouse Pre-designed siRNA Set A
  • HY-RS23772

    Small Interfering RNA (siRNA) Others

    C9 Rat Pre-designed siRNA Set A contains three designed siRNAs for C9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C9 Rat Pre-designed siRNA Set A
    C9 Rat Pre-designed siRNA Set A
  • HY-RS01759

    Small Interfering RNA (siRNA) Others

    C9 Human Pre-designed siRNA Set A contains three designed siRNAs for C9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C9 Human Pre-designed siRNA Set A
    C9 Human Pre-designed siRNA Set A
  • HY-171836

    Endogenous Metabolite Cardiovascular Disease Metabolic Disease Cancer
    c9,t11-CLA is an active isomer of conjugated linoleic acid (CLA). c9,t11-CLA has multiple physiological activities such as anti-cancer, anti-atherosclerosis, anti-obesity, anti-diabetes and anti-hypertension. The main regulatory mechanism of c9,t11-CLA is related to the regulation of cell signaling pathways and metabolic processes. c9,t11-CLA can be used in functional foods, drug development and health-related research .
    c9,t11-CLA
  • HY-171837

    Caspase Cancer
    c9,t11,c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. c9,t11,c15-CLNA has significant anti-proliferation activity against colon cancer cells (IC50: 18.26 μM). c9,t11,c15-CLNA induces pyroptosis by activating the canonical pyroptosis pathway mediated by caspase-1. c9,t11,c15-CLNA can be used in the study of colon cancer .
    c9,t11,c15-CLNA
  • HY-172335

    Liposome Others
    C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs). C9-200-based LNPs encapsulating mRNA encoding erythropoietin (EPO) can induced EPO production and stimulate red blood cell production in mice .
    C9-200
  • HY-124352S

    C9-PQS-d4

    Isotope-Labeled Compounds Bacterial Others
    2-Nonyl-3-hydroxy-4-quinolone-d4 (C9-PQS-d4) is deuterium labeled 2-Nonyl-3-hydroxy-4-quinolone. 2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .
    2-Nonyl-3-hydroxy-4-quinolone-d4
  • HY-RS01760

    Small Interfering RNA (siRNA) Others

    C9orf72 Human Pre-designed siRNA Set A contains three designed siRNAs for C9orf72 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C9orf72 Human Pre-designed siRNA Set A
    C9orf72 Human Pre-designed siRNA Set A
  • HY-RS01761

    Small Interfering RNA (siRNA) Others

    C9orf78 Human Pre-designed siRNA Set A contains three designed siRNAs for C9orf78 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C9orf78 Human Pre-designed siRNA Set A
    C9orf78 Human Pre-designed siRNA Set A
  • HY-RS21991

    Small Interfering RNA (siRNA) Others

    C9orf72 Mouse Pre-designed siRNA Set A contains three designed siRNAs for C9orf72 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C9orf72 Mouse Pre-designed siRNA Set A
    C9orf72 Mouse Pre-designed siRNA Set A
  • HY-155265

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C9-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-5-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C9-NH2 hydrochloride
  • HY-156159

    Ligands for E3 Ligase Cancer
    Thalidomide-NH-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-NH-C9-NH2 hydrochloride
  • HY-138517

    PROTAC Linkers Cancer
    Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Thiol-C9-PEG7
  • HY-138527

    PROTAC Linkers Cancer
    Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Thiol-C9-PEG4
  • HY-138529

    PROTAC Linkers Cancer
    Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Thiol-C9-PEG5
  • HY-149566

    Ligands for E3 Ligase Cancer
    Thalidomide-5-O-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-5-O-C9-NH2 hydrochloride
  • HY-149572

    Ligands for E3 Ligase Cancer
    Thalidomide-4-O-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-4-O-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-O-C9-NH2 hydrochloride
  • HY-138528

    PROTAC Linkers Cancer
    Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Thiol-C9-PEG5-acid
  • HY-138526

    PROTAC Linkers Cancer
    Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Thiol-C9-PEG4-acid
  • HY-139345

    VH032-NH-CO-C9-acid

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-CO-C9-acid is an E3 ligase ligand-linker conjugate that can be connected to the ligand for protein to form PROTACs.
    (S,R,S)-AHPC-CO-C9-acid
  • HY-168277

    E3 Ligase Ligand-Linker Conjugates Cancer
    5-Aminothalidomide-C9-Boc is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) .
    5-Aminothalidomide-C9-Boc
  • HY-153371

    Liposome Others
    50-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.
    50-C2-C9-4tail
  • HY-168235

    Epigenetic Reader Domain E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-Me-amide-C9-acid is a E3 ligase ligand-linker conjugate, used for the synthesis of PROTAC SMARCA2 degrader-31 (HY-168234) .
    (S,R,S)-AHPC-Me-amide-C9-acid
  • HY-160555

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs.
    (S,R,S)-AHPC-CO-C9-NH2
  • HY-160555A

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-CO-C9-NH2 (hydrochloride) is a von Hippel-Lindau (VHL) amino building block that can be used to synthesize E3 ligase ligands required for PROTACs..
    (S,R,S)-AHPC-CO-C9-NH2 hydrochloride
  • HY-169095

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-Me-CO-C9-NH2yes E3Ligase ligand and PROTAC LinkerThe conjugate can be used to synthesize PROTACMolecules, such as MS41 (HY-169093).
    (S,R,S)-AHPC-Me-CO-C9-NH2
  • HY-116095

    Sirtuin Neurological Disease Metabolic Disease
    CypD-IN-5 (compound C-9) is a potent cyclophilin D (CypD) inhibitor. CypD-IN-5 can be used in the study of Alzheimer's disease .
    CypD-IN-5
  • HY-113887

    PGF1β

    Prostaglandin Receptor Drug Isomer Endocrinology
    Prostaglandin F1β (PGF1β) is the C-9 epimer of 1α. Prostaglandin F1β increased the respiratory rate of rabbits .
    Prostaglandin F1β
  • HY-W800740

    Biochemical Assay Reagents Others
    Nonyl 6-bromohexanoate is an aliphatic lipid reagent featuring a C9 chain, an ester, and a C6-bromide.
    Nonyl 6-bromohexanoate
  • HY-156133

    Others Others
    Dihydrospinosyn A aglycone (compound 2) is a derivative of spinosyn A aglycone with a hydrolyzed C9- and C17-glycosidic bond.
    Dihydrospinosyn A aglycone
  • HY-113887A

    11β-PGF1β

    Drug Isomer Endocrinology
    11β-Prostaglandin F (11β-PGF) is a stereoisomer of PGF with inverted C-9 and C-11 hydroxyl groups .
    11β-Prostaglandin F1β
  • HY-169735

    Aurora Kinase Cancer
    Aurora A inhibitor 4 (compound C9) is a potent inhibitor of Aurora A, with the GI50 of 4.26 and 7.08 μM in DU 145 cells and HT-29 cells, respectively .
    Aurora A inhibitor 4
  • HY-W440809

    Biochemical Assay Reagents Others
    Nonyl 8-bromooctanoate is a chemical reagent featuring a bromide linked to a larger ester chain consisting of a C8 ester coupled to a C9 chain. Bromide is easily displaced by nucleophiles in substitution reactions.Nonyl 8-bromooctanoate can be used as an intermediate in building lipids for use in lipid nanoparticles.
    Nonyl 8-bromooctanoate
  • HY-170367

    Bacterial Infection
    Antimicrobial agent-35 (Compound c9) exhibits antibacterial agent, that inhibits S. aureus, E. coli, E. faecalis, and S. maltophilia with MIC of 0.5-2 μg/mL. Antimicrobial agent-35 exhibits cytotoxicity against HT-22 with IC50 of 130.4 μg/mL .
    Antimicrobial agent-35
  • HY-124352

    Bacterial Others
    2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .
    2-Nonyl-3-hydroxy-4-quinolone
  • HY-124209

    Prostaglandin Receptor Endocrinology
    9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist.
    9-keto Fluprostenol
  • HY-N7057S3

    Pelargonic acid-d2; Pelargonic acid-d2 (n-Nonanoic acid, C9 )

    Bacterial Infection
    Nonanoic acid-d2 is the deuterium labeled Nonanoic acid . Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
    Nonanoic acid-d2
  • HY-172177

    Apoptosis HDAC ROCK Cancer
    ROCK/HDAC-IN-2 (Compound C-9) is a ROCK/HDAC inhibitor, with IC50 values of 0.185 µM, 0.8 µM, and 0.7 µM for HDAC6, ROCK1, and ROCK2, respectively. ROCK/HDAC-IN-2 can induce apoptosis and changes in mitochondrial membrane potential in cancer cells, demonstrating significant antitumor activity. ROCK/HDAC-IN-2 can be used in the research of pancreatic ductal adenocarcinoma (PDAC) and triple-negative breast cancer (TNBC) .
    ROCK/HDAC-IN-2
  • HY-W753927

    C18:2(9E,12Z); C18:2 n-6

    Endogenous Metabolite Metabolic Disease
    9(E),12(Z)-Octadecadienoic acid is an ω-6 polyunsaturated fatty acid and an isomer of linoleic acid (HY-N0729) that contains a trans double bond at the C9 position. It has been found as a minor component of bovine milk fat and in partially hydrogenated vegetable oils. 9(E),12(Z)-Octadecadienoic acid levels increase in rabbit meat following supplementation with heated sunflower oil, α-tocopheryl acetate, and zinc.
    9(Z)​,​12(E)​-​Octadecadienoic Acid
  • HY-161943

    Influenza Virus Neurological Disease
    NEU3-IN-1 (compound 963) is a NEU3 inhibitor (Ki: 0.12 μM; IC50: 0.31 μM) based on the 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) scaffold and is a C9 biphenylcarbamate derivative. NEU is a human neuraminidase with 4 isozymes; NEU3-IN-1 is an important tool for studying the function of NEU3 isozymes; its amide and triazole linker analogs are selective for NEU1 and NEU4 isozymes, respectively .
    NEU3-IN-1
  • HY-N12962

    Others Others
    11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .
    11S(12R)-EET
  • HY-176737

    TGF-beta/Smad Inflammation/Immunology
    TGF-β1/Smad-IN-1 (compound C9) is a potent TGF-β1/Smad inhibitor. TGF-β1/Smad-IN-1 inhibits the expression of fibrosis markers (α-SMA and COL1A1) induced by TGF-β1. TGF-β1/Smad-IN-1 shows antifibrotic effects. TGF-β1/Smad-IN-1 has the potential for the research of hepatic fibrosis .
    TGF-β1/Smad-IN-1
  • HY-42034

    Dihydroquinine

    Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase Infection
    Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .
    Hydroquinine
  • HY-N12962A

    Others Others
    11R(12S)-EET is a cis-epoxytrienoic acid (EETs) derivative that is metabolized by cytoplasmic cyclooxygenases. Studies have shown that 14(R), 15(S)-, 11(S),12(R)-, and 8(S),9(R)-EETs are metabolized at significantly higher rates than their enantiomers. Enzyme-catalyzed hydration revealed that water addition was non-regioselective for the 11,12-EET enantiomers, whereas water addition occurred primarily at the C9 position for both enantiomers of 8,9-EET. These results suggest that the metabolic properties of 11R(12S)-EET and other EET enantiomers in enzyme-catalyzed processes are significantly affected by their stereostructures .
    11R(12S)-EET
  • HY-42034R

    Dihydroquinine (Standard)

    Reference Standards Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase Inflammation/Immunology
    Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .
    Hydroquinine (Standard)
  • HY-157581

    PROTACs EGFR Cancer
    MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells .
    MS39
  • HY-W127393

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
    N-Nonanoyl-L-homoserine lactone
  • HY-E70473

    Cytochrome P450 Metabolic Disease
    Human CYP2C9, High-Reductase, a recombinant CYP2C9, is one of the most important cytochrome P450 (CYP) enzymes. Human CYP2C9, Low-Reductase is responsible for drug metabolism reactions that occur in human populations .
    Human CYP2C9,High-Reductase
  • HY-E70460

    Cytochrome P450 Metabolic Disease
    Human CYP2C9, Low-Reductase, a recombinant CYP2C9, is one of the most important cytochrome P450 (CYP) enzymes. Human CYP2C9, Low-Reductase is responsible for drug metabolism reactions that occur in human populations .
    Human CYP2C9,Low-Reductase

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