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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

neural cell

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Akt (3) AMPK (2) Antibiotic (4) Apoptosis (23) Autophagy (2) Bacterial (11) Biochemical Assay Reagents (3) Calcium Channel (3) CaMK (1) Caspase (3) CaSR (7) CCR (1) Chloride Channel (1) COX (13) CRAC Channel (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) DYRK (1) Endogenous Metabolite (13) Epigenetic Reader Domain (1) ERK (1) Estrogen Receptor/ERR (3) Ferroportin (1) Flavivirus (1) Free Fatty Acid Receptor (1) Fungal (5) G-quadruplex (2) GLUT (1) GPR55 (1) HDAC (1) Herbicide (3) HIF/HIF Prolyl-Hydroxylase (1) Histone Methyltransferase (1) Interleukin Related (2) Isotope-Labeled Compounds (7) Keap1-Nrf2 (2) Lipoxygenase (1) LPL Receptor (1) mGluR (1) MicroRNA (1) Monoamine Oxidase (1) mRNA (4) mTOR (1) nAChR (1) NF-κB (1) Notch (2) Orphan Receptor (1) p38 MAPK (1) PACAP Receptor (1) Parasite (1) Phosphodiesterase (PDE) (1) Phospholipase (1) PI3K (2) PKA (2) PKC (1) PKG (2) Reactive Oxygen Species (ROS) (3) Reference Standards (11) Sirtuin (1) STAT (2) Steroid Sulfatase (1) Telomerase (1) TGF-beta/Smad (1) TGF-β Receptor (1) TNF Receptor (2) Transferrin Receptor (1) Trk Receptor (2) TRP Channel (1)
By Research Areas:	Cancer (33) Cardiovascular Disease (4) Endocrinology (3) Infection (10) Inflammation/Immunology (18) Metabolic Disease (4) Neurological Disease (55)
Oligonucleotides:	Flavoring Agents (1) mRNA (4) Sweetening Agents (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor VISTA BCL6 Tim3 BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113845

(+)-Intermedine	Others	Neurological Disease
(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs) .

HY-10591

Neuropathiazol 1 Publications Verification	TGF-β Receptor	Neurological Disease
Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells .

HY-B0141

Estradiol Maximum Cited Publications 108 Publications Verification β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Endocrinology Cancer
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B0141C

Estradiol hemihydrate Maximum Cited Publications 108 Publications Verification β-Estradiol hemihydrate; 17β-Estradiol hemihydrate; 17β-Oestradiol hemihydrate	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Neurological Disease Cancer
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-15036

Diclofenac 15+ Cited Publications	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15038

Diclofenac potassium 15+ Cited Publications	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15036A

Diclofenac diethylamine 15+ Cited Publications	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15037

Diclofenac Sodium 15+ Cited Publications GP 45840	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-158736

Lyso-sulfatide (bovine) ammonium Psychosine 3′-O-sulfate ammonium; Psychosine 3′-sulfate ammonium	Phospholipase	Cancer
Lyso-sulfatide (bovine) ammonium, a derivative of the glycosphingolipid sulfatide, acts as an extracellular signal regulating the migration of a neural precursor cell line (B35 neuroblastoma cells) by rapidly promoting process retraction and cell rounding .

HY-107614G

1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl-sn-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium	TGF-beta/Smad	Neurological Disease
1-Oleoyl lysophosphatidic acid sodium (GMP) is a GMP-grade 1-Oleoyl lysophosphatidic acid sodium (HY-107614) that can be used as an auxiliary reagent in cell therapy. 1-Oleoyl lysophosphatidic acid sodium can stimulate neuronal differentiation in neural progenitor cells from mice or rats, and it also promotes the differentiation of human adipose-derived mesenchymal stem cells into myofibroblast-like cells in vitro by activating the autocrine TGF-β1-Smad signaling pathway .

HY-15036R

Diclofenac (Standard)	Reference Standards COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac (Standard) is the analytical standard of Diclofenac. This product is intended for research and analytical applications. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15038R

Diclofenac potassium (Standard)	Reference Standards COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac (potassium) (Standard) is the analytical standard of Diclofenac (potassium). This product is intended for research and analytical applications. Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15036AR

Diclofenac diethylamine (Standard)	Reference Standards COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac (diethylamine) (Standard) is the analytical standard of Diclofenac (diethylamine). This product is intended for research and analytical applications. Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-16637D

Folic acid disodium 20+ Cited Publications Vitamin B9 disodium; Vitamin M disodium	Endogenous Metabolite DNA/RNA Synthesis	Others Neurological Disease Cancer
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-B1119

Triclosan 5+ Cited Publications	Bacterial Fungal Antibiotic Apoptosis	Infection Cancer
Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-N2740

Agalloside	Sirtuin	Neurological Disease
Agalloside is a neural stem cell differentiation activator that can be found in Aquilaria agallocha .

HY-12323G

ISX-9 Isoxazole 9	Calcium Channel	Cardiovascular Disease Neurological Disease
ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation.

HY-B0141R

Estradiol (Standard) Maximum Cited Publications 108 Publications Verification β-Estradiol(Standard); E2(Standard); 17β-Estradiol(Standard); 17β-Oestradiol (Standard)	Reference Standards Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Endocrinology Cancer
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B1119R

Triclosan (Standard)	Reference Standards Bacterial Fungal Antibiotic Apoptosis	Infection Cancer
Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-N1838

Dehydromaackiain	Others	Neurological Disease
Dehydromaackiain is a potent Neurogenin2 (Ngn2) promoter activator. Dehydromaackiain promotes differentiation of neural stem cells into neurons .

HY-103361

SB297006 1 Publications Verification	CCR	Neurological Disease Endocrinology
SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.

HY-126644

Halocyamine B	Bacterial Fungal	Infection Cancer
Halocyamine B exhibits antimicrobial activity against a variety of bacteria and yeasts. Halocyamine B exhibits cytotoxicity to cultured neural cells of rat fetal brain, mouse neuroblastoma N18 cells, and human hepatoma HepG2 cells .

HY-N0949

(-)-Variabilin	Others	Neurological Disease
(-)-Variabilin (compound 13) is an Neurogenin2 (Ngn2) promoter activator isolated from Butea superba. (-)-Variabilin promotes differentiation of neural stem cells into neurons .

HY-120782A

Yhhu-3792 hydrochloride	Notch	Neurological Disease
Yhhu-3792 hydrochloride is a Notch activator. Yhhu-3792 hydrochloride enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 hydrochloride promotes the expression of Hes3 and Hes5. Yhhu-3792 hydrochloride increases the spatial and episodic memory abilities of mice. Thhu-3792 can be used for the treatment of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury .

HY-120782

Yhhu-3792	Notch	Neurological Disease
Yhhu-3792 is a Notch activator. Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 promotes the expression of Hes3 and Hes5. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Thhu-3792 can be used for the treatment of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury .

HY-139201B

Poly-D-lysine hydrobromide (MW 84000) PDLHB (MW 84000)	CaSR	Neurological Disease Cancer
Poly-D-lysine hydrobromide (MW 84000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201H

Poly-D-lysine hydrobromide (MW ≥300000) PDLHB (MW ≥300000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW ≥300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-122788

N-Oleoyl serinol Oleoyl serinol	Apoptosis	Cancer
N-Oleoyl serinol is a ceramide analog that can be used in stem cell therapy to prevent stem cells from developing into teratomas. N-Oleoyl serinol induces apoptosis in residual pluripotent embryoid body-derived cells (EBCs), prevents teratoma formation, and enriches EBC cells that undergo neural differentiation after transplantation .

HY-139201D

Poly-D-lysine hydrobromide (MW 4000-15000) PDLHB (MW 4000-15000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW 4000-15000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201E

Poly-D-lysine hydrobromide (MW 150000-300000) PDLHB (MW 150000-300000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW 150000-300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201C

Poly-D-lysine hydrobromide (MW 1000-5000) PDLHB (MW 1000-5000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201A

Poly-D-lysine hydrobromide (MW 70000-150000) PDLHB (MW 70000-150000)	Biochemical Assay Reagents CaSR	Neurological Disease Cancer
Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201

Poly-D-lysine hydrobromide (MW 30000-70000) PDLHB (MW 30000-70000)	CaSR	Neurological Disease Metabolic Disease Cancer
Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-B0430B

(±)-Pantothenic acid (±)-Pantothenate; (±)-Vitamin B5	Endogenous Metabolite	Neurological Disease Metabolic Disease
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice .

HY-174560

Human PAX3 mRNA	mRNA	Cancer
Human PAX3 mRNA encodes the human paired box 3 (PAX3) protein, a member of the paired box (PAX) family. PAX3 may regulate cell proliferation, migration and apoptosis and involve in neural development and myogenesis.

HY-174571

Human NEUROG2 mRNA	mRNA	Neurological Disease
Human NEUROG2 mRNA encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells. NEUROG2 plays a role in the differentiation and survival of midbrain dopaminergic neurons.

HY-174558

Human PAX5 mRNA	mRNA	Cancer
Human PAX5 mRNA encodes the human paired box 5 (PAX5) protein, a member of the paired box (PAX) family. PAX5 may play an important role in B-cell differentiation as well as neural development and spermatogenesis.

HY-111253

CYM-5478	LPL Receptor	Neurological Disease
CYM-5478 is a potent and highly selective S1P₂ agonist with an EC₅₀ of 119 nM in a TGFα-shedding assay. CYM-5478 protects neural-derived cell lines against Cisplatin toxicity .

HY-N6953

Garcinone D 3 Publications Verification	STAT Keap1-Nrf2 Reactive Oxygen Species (ROS)	Neurological Disease
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC₅₀ for CDK2/CyclinE1 is 28.23 μM). Garcinone D promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression and enhancing the Nrf2/HO-1 signaling pathway. In addition, Garcinone D blocks the tumor cell cycle by inhibiting CDK2/CyclinE1. Garcinone D can promote the proliferation of C17.2 neural stem cells and inhibit prostate and breast cancer .

HY-P3267A

Apo-Bovine Transferrin	Ferroportin Transferrin Receptor	Neurological Disease
Apo-Bovine Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin can directly bind to hephaestin, which can convert Fe ²⁺ to Fe ³⁺. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1. Apo-Bovine Transferrin can be used in neuroretinal research .

HY-108476

INDY 2 Publications Verification	DYRK	Cancer
INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC₅₀s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a K_i value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells .

HY-W012788

Maltol 2 Publications Verification	Endogenous Metabolite Apoptosis	Infection Neurological Disease
Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .

HY-12323

ISX-9 5+ Cited Publications Isoxazole 9	Calcium Channel	Neurological Disease
ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation. ISX-9 activates Ca ²⁺ influx through both voltage-gated Ca ²⁺ channels and NMDA receptors and increases neuroD expression. ISX-9 also induces cardiomyogenic differentiation of Notch-activated epicardium-derived cells (NECs) .

HY-N6953R

Garcinone D (Standard)	Reference Standards STAT Keap1-Nrf2 Reactive Oxygen Species (ROS)	Neurological Disease
Garcinone D (Standard) is the analytical standard of Garcinone D (HY-N6953). This product is intended for research and analytical applications. Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC₅₀ for CDK2/CyclinE1 is 28.23 μM). Garcinone D promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression and enhancing the Nrf2/HO-1 signaling pathway. In addition, Garcinone D blocks the tumor cell cycle by inhibiting CDK2/CyclinE1. Garcinone D can promote the proliferation of C17.2 neural stem cells and inhibit prostate and breast cancer .

HY-174495

Human EPO mRNA	mRNA	Others
Human EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.

HY-N2045

Musk ketone 1 Publications Verification	PI3K Akt Apoptosis Cytochrome P450	Neurological Disease
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis .

HY-178048

Neuroprotective agent 13	Autophagy	Neurological Disease
Neuroprotective agent 13 is a brain-penetrant 1H-benzo[d]imidazoles compound with neuroprotective effect. Neuroprotective agent 13 can activate autophagy and clear SCMAS accumulation from iPSC-derived neural progenitor cells. Neuroprotective agent 13 can be used for the research of neurological disease, such as neuronal ceroid lipofuscinoses (NCLs) .

HY-178052

Neuroprotective agent 14	Autophagy	Neurological Disease
Neuroprotective agent 14 is a brain-penetrant 1H-benzo[d]imidazoles compound with neuroprotective effect. Neuroprotective agent 14 can activate autophagy and clear SCMAS accumulation from iPSC-derived neural progenitor cells. Neuroprotective agent 14 can be used for the research of neurological disease, such as neuronal ceroid lipofuscinoses (NCLs) .

HY-W018555

D-Cysteine	Endogenous Metabolite Bacterial	Infection Neurological Disease
D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day .

HY-149552

Ac4-5SGlcNAc	Biochemical Assay Reagents	Cancer
Ac4-5SGlcNAc is a pro-inhibitor of carbohydrate-based glycosyltransferases (OGTs). Ac4-5SGlcNAc inhibits o-GlcN acylation and interferes with the effects of o-GlcN on neural induction of human embryonic stem cells (hESCs), and reduces the invasive phenotype of breast cancer cells. Ac4-5SGlcNAc also targets other carbohydrate-processing enzymes .

Cat. No.	Product Name

HY-L017

Stem Cell Signaling Compound Library

2,290 compounds

Adult stem cells are important for tissue homeostasis and regeneration due to their ability to self-renew and generate multiple types of differentiated daughters. Self-renewal is reflected by their capacity to undergo multiple/limitless divisions. Several signaling pathways are involved in self-renewal of stem cells, that is, Notch, Wnt, and Hedgehog pathways or Polycomb family proteins. Recent studies mainly focus on cancer stem cell (CSCs), induced pluripotent stem cell (iPSCs), neural stem cell and maintenance of embryonic stem cell pluripotency. Among them, CSCs have been believed to be responsible for tumor initiation, growth, and recurrence that have implications for cancer therapy.

MCE owns a unique collection of 2,290 compounds that can be used for stem cell regulatory and signaling pathway research.

HY-L013

Neuronal Signaling Compound Library

3,384 compounds

Neuronal Signaling is involved in the regulation of the mechanisms of the central nervous system (CNS) such as its structure, function, genetics and physiology as well as how this can be applied to understand diseases of the nervous system. Every information processing system in the CNS is composed of neurons and glia, neurons have evolved unique capabilities for intracellular signaling (communication within the cell) and intercellular signaling (communication between cells). G protein-coupled receptors (GPCRs), including 5-HT receptor, histamine receptor, opioid receptor, etc. are the largest class of sensory proteins and are important therapeutic targets in Neuronal Signaling. Besides, Notch signaling, such as β- and γ-secretase, also plays multiple roles in the development of the CNS including regulating neural stem cell (NSC) proliferation, survival, self-renewal and differentiation. GPCR dysfunction caused by receptor mutations and environmental challenges contributes to many neurological diseases. Notch signaling in neurons, glia, and NSCs is also involved in pathological changes that occur in disorders such as stroke, Alzheimer's disease and CNS tumors. Thus, targeting Neuronal Signaling, such as notch signaling and GPCRs, can be used as therapeutic interventions for several different CNS disorders.

MCE designs a unique collection of 3,384 Neuronal Signaling-related compounds that act as a useful tool for the research of neuronal regulation and neuronal diseases.

Cat. No.	Product Name	Type

HY-12318G

IBMX (GMP) 3-Isobutyl-1-methylxanthine (GMP); Isobutylmethylxanthine (GMP)	Fluorescent Dye
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor .

HY-13418G

Dorsomorphin dihydrochloride (GMP)

Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP)

Fluorescent Dye

Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) .

HY-107614G

1-Oleoyl lysophosphatidic acid sodium (GMP)

1-Oleoyl-sn-glycero-3-phosphate sodium (GMP); 1-Oleoyl-LPA sodium (GMP)

Fluorescent Dye

1-Oleoyl lysophosphatidic acid sodium (GMP) is a GMP-grade 1-Oleoyl lysophosphatidic acid sodium (HY-107614) that can be used as an auxiliary reagent in cell therapy. 1-Oleoyl lysophosphatidic acid sodium can stimulate neuronal differentiation in neural progenitor cells from mice or rats, and it also promotes the differentiation of human adipose-derived mesenchymal stem cells into myofibroblast-like cells in vitro by activating the autocrine TGF-β1-Smad signaling pathway .

HY-12323G

ISX-9 (GMP) Isoxazole 9 (GMP)	Fluorescent Dye
ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation.

Cat. No.	Product Name	Type

HY-P3267A

Apo-Bovine Transferrin	Native Proteins
Apo-Bovine Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin can directly bind to hephaestin, which can convert Fe ²⁺ to Fe ³⁺. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1. Apo-Bovine Transferrin can be used in neuroretinal research .

HY-12318G

IBMX (GMP) 3-Isobutyl-1-methylxanthine (GMP); Isobutylmethylxanthine (GMP)	Biochemical Assay Reagents
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor .

HY-13418G

Dorsomorphin dihydrochloride (GMP)

Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP)

Biochemical Assay Reagents

HY-148123

Glycerophospholipids, cephalins

Drug Delivery

Glycerophospholipids and cephalins are a class of phospholipid compounds and important components of neural membranes. Glycerophospholipids and cephalins are hydrolysis substrates of phospholipase (such as PLA2, PLC, and PLD). After complete hydrolysis, they produce 1 mol of glycerol, phosphate, ethanolamine, and 2 mol of fatty acids, respectively. Glycerophospholipids and cephalins can maintain membrane structure, fluidity, and ion permeability, and serve as precursors of second messengers such as arachidonic acid and diacylglycerol. Glycerophospholipids and cephalins can regulate signal transduction, cell apoptosis, and membrane transport, and are used in the study of neurodegenerative diseases (such as Alzheimer's disease) .

HY-107614G

1-Oleoyl lysophosphatidic acid sodium (GMP)

1-Oleoyl-sn-glycero-3-phosphate sodium (GMP); 1-Oleoyl-LPA sodium (GMP)

Biochemical Assay Reagents

HY-12323G

ISX-9 (GMP) Isoxazole 9 (GMP)	Biochemical Assay Reagents
ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation.

HY-139201H

Poly-D-lysine hydrobromide (MW ≥300000) PDLHB (MW ≥300000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW ≥300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201D

Poly-D-lysine hydrobromide (MW 4000-15000) PDLHB (MW 4000-15000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW 4000-15000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201E

Poly-D-lysine hydrobromide (MW 150000-300000) PDLHB (MW 150000-300000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW 150000-300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201C

Poly-D-lysine hydrobromide (MW 1000-5000) PDLHB (MW 1000-5000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-112624I

Dextran T3 (MW 3,000)

Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)

Thickeners

Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

Cat. No.	Product Name	Target	Research Area

HY-P3532

[Glp1]-FGL peptide acetate 1 Publications Verification [pGlu1]-FGL peptide acetate; [Pyr1]-FGL peptide acetate	Peptides	Neurological Disease
[Glp1]-FGL peptide acetate is a neural cell adhesion molecule (NCAM) derived motif and can be used for the research of neurogenesis .

HY-P11322

NHIP peptide	Peptides	Neurological Disease
NHIP peptide is a peptide segment containing 20 amino acids located in the nucleus of the cell. NHIP is highly expressed in neuronal derived cells such as LUHMES cells. NHIP peptide can promote the proliferation of 293T cells. NHIP peptide regulates gene networks related to neural development and autism spectrum disorder (ASD) .

HY-P3483

Maxadilan	PACAP Receptor Caspase Apoptosis PKA Interleukin Related TNF Receptor	Cardiovascular Disease Neurological Disease
Maxadilan is a specific irreversible PAC1 receptor agonist and a potent vasodilator peptide present in the salivary glands of sand flies. Maxadilan exhibits anti-apoptotic activity in hADSCs. Maxadilan inhibits pro-inflammatory cytokines (TNF-α) and enhances anti-inflammatory mediators (IL-10). Maxadilan can activate leukocytes and inhibit vascular permeability through PAC1 receptors. Maxadilan promotes neural differentiation of human adipose-derived stem cells. Maxadilan can be used to study endotoxin shock, atherosclerosis, and neurodegenerative diseases ^{[1] [2] [3] [4] [5]}.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113845

(+)-Intermedine	Alkaloids Pyrrole Alkaloids Symphytum officinale L. Plants Boraginaceae	Others
(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs) .

HY-B0141

Estradiol Maximum Cited Publications 108 Publications Verification β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol	Monophenols Classification of Application Fields Sunscreen Source classification Disease markers Phenols Endocrine diseases Cosmetic Research Endogenous metabolite Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-16637D

Folic acid disodium 20+ Cited Publications Vitamin B9 disodium; Vitamin M disodium	Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite DNA/RNA Synthesis
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-N2740

Agalloside	Flavonoids Flavones Thymelaeaceae Source classification Plants Aquilaria sinensis (Lour.) Spreng.	Sirtuin
Agalloside is a neural stem cell differentiation activator that can be found in Aquilaria agallocha .

HY-B0141R

Estradiol (Standard) Maximum Cited Publications 108 Publications Verification β-Estradiol(Standard); E2(Standard); 17β-Estradiol(Standard); 17β-Oestradiol (Standard)	Classification of Application Fields Sunscreen Source classification Disease markers Phenols Endocrine diseases Cosmetic Research Endogenous metabolite Disease Research Fields Steroids Cancer	Reference Standards Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-N6953

Garcinone D 3 Publications Verification	Xanthones Guttiferae Source classification Phenols Polyphenols Garcinia mangostana Linn. Plants	STAT Keap1-Nrf2 Reactive Oxygen Species (ROS)
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC₅₀ for CDK2/CyclinE1 is 28.23 μM). Garcinone D promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression and enhancing the Nrf2/HO-1 signaling pathway. In addition, Garcinone D blocks the tumor cell cycle by inhibiting CDK2/CyclinE1. Garcinone D can promote the proliferation of C17.2 neural stem cells and inhibit prostate and breast cancer .

HY-N1838

Dehydromaackiain	Natural Products Leguminosae Source classification Plants Butea superba Roxb. ex Willd.	Others
Dehydromaackiain is a potent Neurogenin2 (Ngn2) promoter activator. Dehydromaackiain promotes differentiation of neural stem cells into neurons .

HY-126644

Halocyamine B	Natural Products Animals Marine natural products Source classification Other marine organisms	Bacterial Fungal
Halocyamine B exhibits antimicrobial activity against a variety of bacteria and yeasts. Halocyamine B exhibits cytotoxicity to cultured neural cells of rat fetal brain, mouse neuroblastoma N18 cells, and human hepatoma HepG2 cells .

HY-N0949

(-)-Variabilin	Natural Products Leguminosae Source classification Plants Butea superba Roxb. ex Willd.	Others
(-)-Variabilin (compound 13) is an Neurogenin2 (Ngn2) promoter activator isolated from Butea superba. (-)-Variabilin promotes differentiation of neural stem cells into neurons .

HY-B0430B

(±)-Pantothenic acid (±)-Pantothenate; (±)-Vitamin B5	Other disease Disease markers Endogenous metabolite	Endogenous Metabolite
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice .

HY-W012788

Maltol 2 Publications Verification	Panax ginseng C. A. Meyer Natural Products Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer	Endogenous Metabolite Apoptosis
Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .

HY-N6953R

Garcinone D (Standard)	Xanthones Guttiferae Source classification Phenols Polyphenols Garcinia mangostana Linn. Plants	Reference Standards STAT Keap1-Nrf2 Reactive Oxygen Species (ROS)
Garcinone D (Standard) is the analytical standard of Garcinone D (HY-N6953). This product is intended for research and analytical applications. Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC₅₀ for CDK2/CyclinE1 is 28.23 μM). Garcinone D promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression and enhancing the Nrf2/HO-1 signaling pathway. In addition, Garcinone D blocks the tumor cell cycle by inhibiting CDK2/CyclinE1. Garcinone D can promote the proliferation of C17.2 neural stem cells and inhibit prostate and breast cancer .

HY-W018555

D-Cysteine	Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Endogenous Metabolite Bacterial
D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day .

HY-W012788R

Maltol (Standard)	Panax ginseng C. A. Meyer Microorganisms Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite Araliaceae	Reference Standards Endogenous Metabolite Apoptosis
Maltol (Standard) is the analytical standard of Maltol. This product is intended for research and analytical applications. Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .

HY-130413

Protectin D1 Neuroprotectin D1; NPD1	Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite PI3K Akt HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Caspase Interleukin Related MicroRNA
Protectin D1, a neuroprotectin D1 produced by neuronal cells, is a member of a newly discovered family of bioactive products derived from docosahexaenoic acid. Protectin D1 also serves as a specialized pro-resolving mediator, exhibiting effective in vivo pro-resolving activity in various human disease models. Additionally, Protectin D1 is an inhibitor of NALP3 inflammasomes and regulates the PI3K/AKT and HIF-1α signaling pathways. Protectin D1 exerts anti-inflammatory effects by reducing ROS levels, inhibiting the expression of NALP3, ASC, and Caspase-1, and consequently decreasing the release of pro-inflammatory cytokines IL-1β and IL-18. Furthermore, Protectin D1 enhances miRNA-210 expression, activates the PI3K/AKT signaling pathway, and exerts cardioprotective effects. Protectin D1 holds promise for research in cardiovascular diseases and inflammatory disorders .

HY-W018555R

D-Cysteine (Standard)	Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Reference Standards Endogenous Metabolite Bacterial
D-Cysteine (Standard) is the analytical standard of D-Cysteine. This product is intended for research and analytical applications. D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day[1][2][3][4].

HY-N6588

3,4,5-Tricaffeoylquinic acid 3,4,5-triCQA	Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plants Convolvulaceae Inflammation/Immunology Disease Research Fields Ipomoea batatas (Linn.) Lamarck	Akt NF-κB
3,4,5-Tricaffeoylquinic acid (3,4,5-triCQA) inhibits tumor necrosis factor-α-stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-κB-pathways. 3,4,5-Tricaffeoylquinic acid induces cell cycle arrest at G0/G1, actin cytoskeleton organization, chromatin remodeling, neuronal differentiation, and bone morphogenetic protein signaling in human neural stem cells. 3,4,5-Tricaffeoylquinic acid has the potential for the research of aging-associated diseases .

HY-Y0337

L-Cysteine 5+ Cited Publications Cysteine	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite ERK
L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent .

HY-W019870A

Glufosinate	Microorganisms Source classification	Herbicide
Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity .

HY-N16121

12-Deoxyphorbol 13-isobutyrate	Euphorbia triangularis Desf. Terpenoids Source classification Diterpenoids Euphorbiaceae Plants	PKC
12-Deoxyphorbol 13-isobutyrate (ER272) (DPB), a diterpene, is a PKCα activator. 12-Deoxyphorbol 13-isobutyrate can be isolated from Euphorbia resinifera's latex. 12-Deoxyphorbol 13-isobutyrate facilitates neural stem cells (NSCs) proliferation and activation as well as TGFα release in a reaction dependent on PKCα activation. 12-Deoxyphorbol 13-isobutyrate increases cognitive performance and hippocampal neurogenesis in senescence-accelerated mouse-prone (SAMP8) models. 12-Deoxyphorbol 13-isobutyrate can be used for neurodegenerative diseases research .

HY-B2167R

Docosahexaenoic acid (Standard) DHA (Standard); Cervonic acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite Cardiovascular System Disorder	Reference Standards Endogenous Metabolite
Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC₅₀ for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .

Species:	Human (13) Mouse (4) Rat (1)
Tag:	His (12) Tag Free (2) Avi (2) Fc (4)
Source:	HEK293 (17) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70687

	NCAM-1/CD56 Protein, Human (HEK293, His) CD56; NCAM-1; CD56 antigen; MSK39; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (HEK293, His) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P75346

	CHL1 Protein, Mouse (HEK293) neural cell adhesion molecule L1-like protein; CHL1; CALL	Mouse	HEK293
	CHL1 Protein, Mouse (HEK293) is the recombinant mouse-derived CHL1 protein, expressed by HEK293, with tag free.

HY-P75347

	CHL1 Protein, Human (HEK293, His) neural cell adhesion molecule L1-like protein; CHL1; CALL	Human	HEK293
	CHL1 Protein, Human (HEK293, His) is the recombinant human-derived CHL1 protein, expressed by HEK293, with C-His labeled tag.

HY-P704799

	NCAM-1/CD56 Protein, Human (699a.a, HEK293, His) CD56; NCAM-1; CD56 antigen; MSK39; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (699a.a, HEK293, His) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293, with C-His labeled tag.

HY-P704806

	NCAM-1/CD56 Protein, Human (699a.a, HEK293, Fc) CD56; NCAM-1; CD56 antigen; MSK39; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (699a.a, HEK293, Fc) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293, with C-hFc labeled tag.

HY-P704807

	NCAM-1/CD56 Protein, Human (699a.a, HEK293, Llama Fc) CD56; NCAM-1; CD56 antigen; MSK39; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (699a.a, HEK293, Llama Fc) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293, with C-Llama Fc labeled tag.

HY-P75344

	CHL1 Protein, Mouse (HEK293, His) neural cell adhesion molecule L1-like protein; CHL1; CALL	Mouse	HEK293
	CHL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CHL1 protein, expressed by HEK293, with C-His labeled tag.

HY-P75345

	CHL1 Protein, Mouse (HEK293, hFc) neural cell adhesion molecule L1-like protein; CHL1; CALL	Mouse	HEK293
	CHL1 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived CHL1 protein, expressed by HEK293, with C-hFc labeled tag.

HY-P76505

	OCAM/NCAM2 Protein, Human (HEK293, Fc) neural cell adhesion molecule 2; NCAM-2; NCAM21	Human	HEK293
	OCAM/NCAM2 proteins are potential key players in selective fasciculations and interregional projections in olfactory axons. Its specific mechanism and functional significance in guiding axonal development remain to be further elucidated. OCAM/NCAM2 Protein, Human (HEK293, Fc) is the recombinant human-derived OCAM/NCAM2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76506

	OCAM/NCAM2 Protein, Human (HEK293, His) neural cell adhesion molecule 2; NCAM-2; NCAM21	Human	HEK293
	OCAM/NCAM2 proteins are potential key players in selective fasciculations and interregional projections in olfactory axons. Its specific mechanism and functional significance in guiding axonal development remain to be further elucidated. OCAM/NCAM2 Protein, Human (HEK293, His) is the recombinant human-derived OCAM/NCAM2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70843

	NEDD8 Protein, Human neural precursor cell expressed developmentally down-regulated protein 8; NEDD8; Neddylin; Ubiquitin-like protein Nedd8	Human	E. coli
	NEDD8 is an important ubiquitin-like protein that plays a key role in cell cycle regulation and embryogenesis by binding to specific proteins such as cullin and p53/TP53. Its binding to cullin is critical for recruiting E2 enzymes to the cullin-RING-based E3 ubiquitin-protein ligase complex, thereby enabling degradation of regulatory proteins. NEDD8 Protein, Human is the recombinant human-derived NEDD8 protein, expressed by E. coli , with tag free.

HY-P73749

	NCAM-1/CD56 Protein, Rat (HEK293, His) 1 Publications Verification CD56; MSK39; NCAM-1; neural cell adhesion molecule 1; NCAM	Rat	HEK293
	The NCAM-1/CD56 protein is a key cell adhesion molecule that plays a key role in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth.Its interaction with MDK contributes to complex cellular interactions in neural development.NCAM-1/CD56 Protein, Rat (HEK293, His) is the recombinant rat-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74224

	Contactin-1/CNTN1 Protein, Mouse (HEK293, His) CNTN1; Contactin1; F11; F3; neural cell surface protein F3	Mouse	HEK293
	Contactin-1/CNTN1 protein mediates surface interactions during nervous system development. It forms paranodal axo-glial junctions in peripheral nerves and facilitates axon-glia signaling through CNTNAP1. It acts as a ligand for NOTCH1, promoting NOTCH1 activation. Contactin-1/CNTN1 also interacts with TNR, inhibiting neurite outgrowth. It binds to CNTNAP1 and PTPRZ1, and forms a complex with NRCAM, PTPRB, and TASOR. Contactin-1/CNTN1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Contactin-1/CNTN1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74791

	L1CAM Protein, Human (HEK293, His) 1 Publications Verification neural cell adhesion molecule L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5	Human	HEK293
	The L1CAM protein is a neural cell adhesion molecule that plays a critical role in cell adhesion dynamics and initiation of tyrosine kinase receptor transmembrane signaling. Its importance spans brain development, affecting processes such as neuronal migration, axonal growth, fasciculations, and synaptogenesis. L1CAM Protein, Human (HEK293, His) is the recombinant human-derived L1CAM protein, expressed by HEK293 , with C-His labeled tag.

HY-P75932

	NCAM-1/CD56 Protein, Human (HEK293, His-Avi) CD56; CD56 antigen; MSK39; N-CAM-1; neural cell adhesion molecule 1; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (HEK293, His-Avi) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P75933

	NCAM-1/CD56 Protein, Human (HEK293, His, solution) CD56; CD56 antigen; MSK39; N-CAM-1; neural cell adhesion molecule 1; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (HEK293, His, solution) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75932A

	NCAM-1/CD56 Protein, Human (Biotinylated, HEK293, His-Avi) CD56; CD56 antigen; MSK39; N-CAM-1; neural cell adhesion molecule 1; NCAM	Human	HEK293
	Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived NCAM-1/CD56, expressed by HEK293, with C-Avi, C-His labeled tag.

HY-P700417

	L1CAM Protein, Human (HEK293, C-His) L1 cell adhesion molecule; antigen identified by monoclonal R1 , HSAS, HSAS1, MASA, MIC5, S10, SPG1; neural cell adhesion molecule L1; CD171; antigen identified by monoclonal R1; S10; HSAS; MASA; MIC5; SPG1; CAML1; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1	Human	HEK293
	The L1CAM protein is a neural cell adhesion molecule that plays a critical role in cell adhesion dynamics and initiation of tyrosine kinase receptor transmembrane signaling. Its importance spans brain development, affecting processes such as neuronal migration, axonal growth, fasciculations, and synaptogenesis. L1CAM Protein, Human (HEK293, C-His) is the recombinant human-derived L1CAM protein, expressed by HEK293 , with C-10*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-15036S1

Diclofenac-13C6
Diclofenac- ¹³C₆ is the ¹³C₆ labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

HY-15036S

Diclofenac-d4
Diclofenac-d₄ is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15037S1

Diclofenac-d4 sodium

Diclofenac-d₄ (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-W653962

Triclosan-13C6

Triclosan- ¹³C₆ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-W747491

Triclosan-13C12

Triclosan- ¹³C₁₂ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-15037S2

Diclofenac-13C6 sodium

Diclofenac- ¹³C₆ (Sodium) is the ¹³C₆ labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

HY-W012788S

Maltol-d3

Maltol-d₃ is a deuterium labeled Maltol (HY-W012788). Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .

HY-15037S

Diclofenac-13C6 sodium heminonahydrate

Diclofenac- ¹³C₆ (sodium heminonahydrate) is the ¹³C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83477

	CD56 Antibody (YA3222) NCAM1; NCAM; neural cell adhesion molecule 1; N-CAM-1; NCAM-1; CD56	WB, IHC-P, ICC/IF, IP, FC	Human
	CD56 Antibody (YA3222) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD56.

HY-P80240

	NEDD8 Antibody (YA273) FLJ43224 antibody; MGC104393 antibody; MGC125896 antibody; MGC125897 antibody; NED8 antibody; NEDD 8 antibody; NEDD-8 antibody; Nedd8 antibody; NEDD8_HUMAN antibody; Neddylin antibody; neural precursor cell expressed developmentally down regulated 8 antibody; neural precursor cell expressed developmentally down regulated gene 8 antibody; neural precursor cell expressed developmentally down-regulated protein 8 antibody; Rub1 antibody; Ubiquitin like protein Nedd 8 antibody; Ubiquitin like protein Nedd8 antibody; Ubiquitin-like protein Nedd8 antibody;	WB, ICC/IF, IHC-P, IP	Human, Rat
	NEDD8 Antibody (YA273) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NEDD8.

HY-P83404

	L1CAM Antibody (YA3149) L1CAM; CAML1; MIC5; neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171	WB, IHC-P	Human
	L1CAM Antibody (YA3149) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to L1CAM.

HY-P85951

	CD56 Antibody (YA5643) antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; neural cell adhesion molecule 1; neural cell adhesion molecule NCAM; OTTHUMP00000235666	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	CD56 Antibody (YA5643) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD56.

HY-P84998

	CD56 Antibody (YA4690) antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule; neural; 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; neural cell adhesion molecule 1; neural cell adhesion molecule NCAM; OTTHUMP00000235666; CD56 nanobody;	ELISA, FC	Human
	CD56 Antibody (YA4690) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD56.

HY-P81625

	L1CAM Antibody (YA1370) L1CAM; CAML1; MIC5; neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171	FC, ELISA	Human
	L1CAM Antibody (YA1370) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to L1CAM.

HY-P85443

	L1CAM Antibody (YA5135) L1CAM; CAML1; MIC5; neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD antigen CD171	WB	Human, Mouse, Rat, Dog, Rabbit
	L1CAM Antibody (YA5135) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to L1CAM.

HY-P82135

	RPL10A Antibody (YA1880) RPL10A; NEDD6; 60S ribosomal protein L10a; CSA-19; neural precursor cell expressed developmentally down-regulated protein 6; NEDD-6	WB	Human, Mouse, Rat
	RPL10A Antibody (YA1880) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RPL10A.

HY-P83027

	Cleaved-Caspase 2 Antibody (YA2772) Caspase-2; Caspase 2; Caspase2; CASP-2; neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; CASP2; ICH1; NEDD2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Cleaved-Caspase 2 Antibody (YA2772) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cleaved-Caspase 2.

HY-P86850

	Delta-catenin Antibody (YA6543) ARM-repeat protein antibody; Catenin (cadherin associated protein) delta 2 antibody; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody; Catenin delta 2 antibody; Catenin delta-2 antibody; CTND2_HUMAN antibody; CTNND 2 antibody; Ctnnd2 antibody; Delta catenin antibody; Delta-catenin antibody; ARM-repeat protein antibody; Catenin (cadherin associated protein) delta 2 antibody; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody; Catenin delta 2 antibody; Catenin delta-2 antibody; CTND2_HUMAN antibody; CTNND 2 antibody; Ctnnd2 antibody; Delta catenin antibody; Delta-catenin antibody; GT 24 antibody; GT24 antibody; neural plakophilin related arm repeat protein antibody; neural plakophilin related armadillo repeat protein antibody; neural plakophilin-related ARM-repeat protein antibody; neural plakophilin-related, Neurojungin antibody; Neurojungin antibody; NPRAP antibody; T cell delta catenin antibody;	WB, IHC-P, IP, IHC-F	Human, Mouse, Rat
	Delta-catenin Antibody (YA6543) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Delta-catenin.

HY-P86985

	NEDD4L Antibody (YA6678) E3 ubiquitin protein ligase NEDD4 like protein antibody; E3 ubiquitin-protein ligase NEDD4-like antibody; KIAA0439 antibody; NED4L_HUMAN antibody; NEDD4 2 antibody; NEDD4-2 antibody; NEDD4 2c antibody; Nedd4-2 antibody; NEDD4-2a antibody; NEDD4.2 antibody; E3 ubiquitin protein ligase NEDD4 like protein antibody; E3 ubiquitin-protein ligase NEDD4-like antibody; KIAA0439 antibody; NED4L_HUMAN antibody; NEDD4 2 antibody; NEDD4-2 antibody; NEDD4 2c antibody; Nedd4-2 antibody; NEDD4-2a antibody; NEDD4.2 antibody; NEDD4b antibody; NEDD4L antibody; NEDD4La antibody; NEDD4Lb antibody; NEDD4Lc antibody; NEDD4Ld antibody; NEDD4Le antibody; NEDD4Lf antibody; NEDD4Lg antibody; NEDD4Lh antibody; NEDL3 antibody; neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase antibody; neural precursor cell expressed, developmentally down regulated 4 like antibody; RSP5 antibody; Ubiquitin protein ligase Rsp5 antibody;	WB, IP	Human
	NEDD4L Antibody (YA6678) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NEDD4L.

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Cat. No.	Product Name		Classification

HY-W012788

Maltol 2 Publications Verification		Sweetening Agents Flavoring Agents
Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .

HY-174560

Human PAX3 mRNA		mRNA
Human PAX3 mRNA encodes the human paired box 3 (PAX3) protein, a member of the paired box (PAX) family. PAX3 may regulate cell proliferation, migration and apoptosis and involve in neural development and myogenesis.

HY-174571

Human NEUROG2 mRNA		mRNA
Human NEUROG2 mRNA encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells. NEUROG2 plays a role in the differentiation and survival of midbrain dopaminergic neurons.

HY-174558

Human PAX5 mRNA		mRNA
Human PAX5 mRNA encodes the human paired box 5 (PAX5) protein, a member of the paired box (PAX) family. PAX5 may play an important role in B-cell differentiation as well as neural development and spermatogenesis.

HY-174495

Human EPO mRNA		mRNA
Human EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.

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