Search Result

Results for "

active peptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (7) CGRP Receptor (8) Formyl Peptide Receptor (FPR) (2) Natriuretic Peptide Receptor (NPR) (1) Adenylate Cyclase (1) Akt (2) Amino Acid Decarboxylase (1) Amino Acid Derivatives (3) AMPK (1) Amylases (1) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (1) Angiotensin Receptor (6) Angiotensin-converting Enzyme (ACE) (8) Antibiotic (17) APC (1) Apelin Receptor (APJ) (3) Apoptosis (16) Arenavirus (1) Arp2/3 Complex (1) Autophagy (2) Bacterial (73) Bcl-2 Family (10) Bcr-Abl (1) Biochemical Assay Reagents (39) Bradykinin Receptor (3) Btk (1) c-Kit (1) Calcium Channel (5) Calmodulin (1) CaMK (1) Carboxypeptidase (1) Casein Kinase (1) Caspase (4) CaSR (1) Cathepsin (1) CCR (1) CD3 (1) CDK (3) CFTR (4) CHIKV (1) Cholecystokinin Receptor (6) Complement System (1) COX (1) CRFR (2) Cytochrome P450 (1) DAPK (1) Dengue Virus (1) Dipeptidyl Peptidase (2) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Isomer (1) Drug-Linker Conjugates for ADC (1) DYRK (1) EAAT (5) EBV (3) EGFR (1) Elastase (3) Endogenous Metabolite (6) Endothelin Receptor (8) Epigenetic Reader Domain (1) ERK (3) Estrogen Receptor/ERR (2) Factor XI (1) FAK (1) Ferroptosis (1) FGFR (1) FLT3 (1) Fluorescent Dye (14) Fungal (11) Furin (1) G Protein-coupled Receptor Kinase (GRK) (1) Gap Junction Protein (3) GCGR (11) GHR (1) GHSR (1) GLP Receptor (8) Glucocorticoid Receptor (1) Glutathione Peroxidase (1) GnRH Receptor (18) GSK-3 (2) Guanylate Cyclase (1) HCV (1) Histone Demethylase (4) Histone Methyltransferase (2) HIV (10) HPV (1) IFNAR (1) iGluR (2) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (3) Insulin Receptor (5) Integrin (4) Interleukin Related (5) IRAK (1) Isotope-Labeled Compounds (8) JAK (1) Keap1-Nrf2 (2) LIM Kinase (LIMK) (1) Liposome (1) MARCKS (1) MDM-2/p53 (2) Melanocortin Receptor (2) mGluR (1) MHC (3) Microtubule/Tubulin (1) Mineralocorticoid Receptor (1) MMP (3) N-myristoyltransferase (1) NADPH Oxidase (5) Necroptosis (1) Neprilysin (6) Neurokinin Receptor (2) Neuropeptide B/W Receptor (1) Neurotensin Receptor (6) NF-κB (2) NO Synthase (2) NOD-like Receptor (NLR) (6) Nuclear Factor of activated T Cells (NFAT) (4) Opioid Receptor (2) Orexin Receptor (OX Receptor) (3) Orphan Receptor (1) Oxytocin Receptor (2) PACAP Receptor (1) Parasite (3) PDK-1 (1) PGE synthase (1) Phosphatase (4) PI3K (2) Pim (1) PKA (1) PKC (7) Potassium Channel (1) Prolyl Endopeptidase (PREP) (5) Protease Activated Receptor (PAR) (11) Proteasome (1) Protein Arginine Deiminase (1) Proton Pump (1) PTHR (1) Reactive Oxygen Species (ROS) (8) Reference Standards (9) Renin (2) Ribosomal S6 Kinase (RSK) (1) ROCK (1) SARS-CoV (3) Ser/Thr Kinase (1) Ser/Thr Protease (3) Sodium Channel (1) Src (2) STAT (3) Tau Protein (3) TGF-beta/Smad (1) Thrombin (3) Thrombopoietin Receptor (2) TNF Receptor (4) Toll-like Receptor (TLR) (1) Transmembrane Glycoprotein (4) TRP Channel (1) Vasopressin Receptor (2) VEGFR (2) Virus Protease (1) YAP (1) β-catenin (1) γ-secretase (2)
By Research Areas:	Cancer (68) Cardiovascular Disease (51) Endocrinology (25) Infection (70) Inflammation/Immunology (55) Metabolic Disease (51) Neurological Disease (58)
Click Chemistry:	Alkynes (3)

466

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

680

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Formyl Peptide Receptor (FPR) Connective Peptide Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) RXFP Receptor CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3281

FGL peptide	Biochemical Assay Reagents	Others
FGL peptide, is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2784

[Tyr8]-Substance P	Biochemical Assay Reagents	Others
[Tyr8]-Substance P is an **active peptide**. [Tyr8]-Substance P can be used for the research of various biochemical .

HY-P3623

Biotin-Glucagon-Like Peptide 1 (7-36) amide, human	Fluorescent Dye	Others
Biotin-Glucagon-Like Peptide 1 (7-36) amide, human is a biologically **active peptide*. Biotin-Glucagon-Like Peptide* 1 (7-36) amide, human can be used for the research of various biochemical studies.

HY-P4352

HIV-2 Peptide	HIV	Others
HIV-2 Peptide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4463

(Des-Pyr1)-LHRH	GnRH Receptor	Others
(Des-Pyr1)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4536

(D-Leu6)-LHRH (1-8)	GnRH Receptor	Others
(D-Leu6)-LHRH (1-8) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4351

HIV-1 gag Protein p24 (194-210)	HIV	Others
HIV-1 gag Protein p24 (194-210) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3588

N-Acetyl semax amidate	Biochemical Assay Reagents	Others
N-Acetyl semax amidate is a biologically **active peptide**. N-Acetyl semax amidate can be used for the research of various biochemical studies.

HY-P4570

(D-Ser6,Azagly10)-LHRH	GnRH Receptor	Others
(D-Ser6,Azagly10)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4538

(D-Leu6,Pro-NHEt9)-LHRH (4-9)	GnRH Receptor	Others
(D-Leu6,Pro-NHEt9)-LHRH (4-9) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4534

(D-His2,D-Trp6)-LHRH (D-His2)-Triptorelin	GnRH Receptor	Others
(D-His2,D-Trp6)-LHRH ((D-His2)-Triptorelin) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3610

[Ala18] Endothelin-1, human	Endothelin Receptor	Others
[Ala18] Endothelin-1, human is a biologically **active peptide**. [Ala18] Endothelin-1, human can be used for the research of various biochemical studies.

HY-P4442

(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH	GnRH Receptor	Others
(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4467

(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH (Des-Pyr1)-Leuprolide	GnRH Receptor	Others
(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4447

(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH	GnRH Receptor	Others
(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4440

(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH	GnRH Receptor	Others
(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4445

(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH	GnRH Receptor	Others
(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4441

(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH	GnRH Receptor	Others
(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3551

[Ala2] Met-Enkephalinamide	Biochemical Assay Reagents	Others
[Ala2] Met-Enkephalinamide is an **active peptide**. [Ala2] Met-Enkephalinamide can be used for the research of various biochemical studies .

HY-P3586

HKPao Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide	Apoptosis	Cancer
HKPao (Hunter-killer peptide ao) is a biologically **active peptide*. HKPao (Hunter-killer peptide* ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles .

HY-P3540

Y-{d-Trp}-GFM-NH2	Biochemical Assay Reagents	Others
Y-{d-Trp}-GFM-NH2 is an **active peptide**. Y-{d-Trp}-GFM-NH2 can be used for the research of various biochemical studies .

HY-W090942

Z-Gly-Gly-Phe-OH	Endogenous Metabolite Sodium Channel	Others
Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC₅₀ of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis .

HY-P3603

a-TGF (34-43), rat	TGF-beta/Smad	Inflammation/Immunology
a-TGF (34-43), rat is an **active peptide**. a-TGF (34-43), rat can be used in the research of immunity .

HY-P5971A

TCMCB07 TFA	Melanocortin Receptor	Metabolic Disease
TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia .

HY-P5774

Leu-Valorphin-Arg	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Leu-Valorphin-Arg (LVV-hemorphin-6), an opioid active peptide, is an angiotensin converting enzyme (ACE) inhibitor. Leu-Valorphin-Arg can be used for hypertension research .

HY-P5971

TCMCB07 Mifomelatide	Melanocortin Receptor	Metabolic Disease
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia. TCMCB07 has potential transport capabilities .

HY-Y1703

HATU	Biochemical Assay Reagents	Others
HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds .

HY-148263

Biotin-PEG-Thiol (MW 2000)	Fluorescent Dye	Cancer
Biotin-PEG-Thiol (MW 2000) is an active compound. Biotin-PEG-Thiol (MW 2000) is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG-Thiol (MW 2000) can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG-Thiol (MW 2000) is widely used in the research of agent release and nano new materials .

HY-P5498

N36 peptide	HIV	Others
N36 peptide is a biological active peptide. (HIV-1 gp41 fusion peptide)

HY-P5463

C18G	Bacterial	Others
C18G is a biological active peptide. (C18G is a synthetic α-helical peptide derived from human platelet factor IV. This peptide was found to be antibacterial and is active against Salmonella.)

HY-P5564

BTL peptide	Fungal	Infection
BTL peptide is an antifungal peptide. BTL peptide is active against B. maydis, A. brassicae, A. niger and C. personata .

HY-P5456

KRPpSQRHGSKY-NH2	PKC	Others
KRPpSQRHGSKY-NH2 is a biological active peptide. (This is a phosphorylated PKC substrate peptide)

HY-P5359

FLLRN TRAP-6 (2-6)	Protease Activated Receptor (PAR)	Others
FLLRN is a biological active peptide. (PAR1-specific antagonist peptide)

HY-P5388

Renin inhibitor peptide,rat	Renin	Others
Renin inhibitor peptide,rat is a biological active peptide. (A specific rat renin inhibitor.)

HY-P5450

PDKtide	PDK-1	Others
PDKtide is a biological active peptide. (This peptide is a substrate for PDK1 (Phosphatidylinositide-Dependent Kinase 1).)

HY-P5433F

IRS-1 Peptide, FAM labeled	Insulin Receptor	Others
IRS-1 Peptide, FAM labeled is a biological active peptide. (Insulin receptor substrate)

HY-P5391

LL-37(17-32)	Bacterial	Others
LL-37(17-32) is a biological active peptide. (This peptide is an active segment of LL-37, a peptide derived from the C-terminal domain of human cathelicidin antimicrobial peptide. It has been reported that the LL17-32 peptide exhibits reversal effect on ABCG2-mediated multidrug resistance in cancer cell lines.)

HY-E70017

Peptidase, microorganism Erepsin; Peptidase (IMPa)	Others	Others
Peptidase (IMPa) (Erepsin) is catalytically active enzyme that cleaves peptide bonds in proteins and peptides by hydrolysis .

HY-P5474

PMAP-23	Bacterial	Others
PMAP-23 is a biological active peptide. (an antimicrobial peptide (AMP) derived from porcine myeloid.)

HY-P5384

sgp91 ds-tat	NADPH Oxidase	Others
sgp91 ds-tat is a biological active peptide. (This is a scrambled control peptide for gp91 ds-tat.)

HY-P2880

PHI-27 (porcine)	GCGR	Others
PHI-27 (porcine) is a 27 amino acid peptide.PHI-27 (porcine) is used to find peptide hormones and other active peptides .

HY-P5447

RRLIEDAEpYAARG	Phosphatase	Others
RRLIEDAEpYAARG is a biological active peptide. (Phosphatase substrate.)

HY-P5710

LCI peptide	Bacterial	Infection
LCI peptide is an antimicrobial peptide with antibacterial activity. LCI peptide is active against plant pathogens, Xanthomonas and Pseudomonas, including E. coli, Gentamicin-resistant MRSA and Xoo .

HY-P5431

Insulin receptor (1142-1153), pTyr1150	Insulin Receptor	Others
Insulin receptor (1142-1153), pTyr1150 is a biological active peptide. (Peptide used as insulin receptor tyrosine kinase substrate.)

HY-P1527

Bim BH3 1 Publications Verification	Bcl-2 Family	Others
Bim BH3 is a biological active peptide. (This Bim peptide belongs to the pro-apoptotic Bcl-2 family of proteins.)

HY-P1897

Fibronectin Active Fragment Control	Integrin	Inflammation/Immunology
Fibronectin Active Fragment Control is an active peptide fragment of fibronectin. Fibronectin is a glycoprotein interacting with integrins .

HY-P5555

LMW peptide	Bacterial	Infection
LMW peptide is an antimicrobial peptide. LMW peptide is active against Gram-positive and Gram-negative bacterial, such as B. subtilis, L. monocytogenes, E. coli, P. aeruginosa, V. cholera .

HY-P5432

IRAK-4 Peptide substrate IRAK-1 (360-380)	IRAK	Others
IRAK-4 Peptide substrate (IRAK-1 (360-380)) is a biological active peptide. (This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4)

HY-P5449

p70 S6 Kinase substrate	Ribosomal S6 Kinase (RSK)	Others
p70 S6 Kinase substrate is a biological active peptide. (This peptide is a substrate for p70 ribosomal S6 kinase.)

HY-P5324

Bad BH3 (mouse)	Bcl-2 Family	Others
Bad BH3 (mouse) is a biological active peptide. (This is a bcl-2 binding peptide. This peptide is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165.)

Cat. No.	Product Name

HY-L105

Peptide Library

2,062 compounds

Peptides are a group of biologically active substances that are involved in various cellular functions of organisms. Peptides are often used in functional analysis, vaccine research and especially in the field of drug research and development. At present, more than 80 peptide drugs have reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis, multiple sclerosis, HIV infection and chronic pain.

MedChemExpress (MCE) offers a comprehensive collection of 2,062 peptides, including bioactive peptides, amino acid derivatives, and blocking peptides. MCE Peptide Library can be used for peptide library screening, peptide drug discovery, vaccine development, target verification, structural activity research, etc.

HY-L143

Marine-Sourced Natural Product Library

62 compounds

Oceans cover more than 70% of the Earth’s surface and host a huge species diversity. Marine organisms are considered the most recent source of bioactive natural products after terrestrial plants and nonmarine microorganisms. Marine biological sources are taxonomically diverse and include sponges, tunicates, corals, mollusks, fungi, and sediment-derived bacteria.

Marine organisms can produce a plethora of small molecules with novel chemical structures and potent biological properties, being a rich source for the discovery of pharmacologically active compounds, already with several marine-derived agents approved as drugs. Ziconotide, a peptide originally discovered in a tropical cone snail, was the first marine-derived compound to be approved in the United States in December 2004 for the treatment of pain. Then, in October 2007, Trabectedin became the first marine anticancer drug to be approved in the European Union.

MCE offers a unique collection of 62 marine-sourced natural products which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE marine-sourced natural product library is an important source for drug discovery and development.

Cat. No.	Product Name	Type

HY-137834A

Gly-Pro-AMC	Fluorescent Dyes/Probes
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)

HY-135414A

Cyanine5 NHS ester bromide	Fluorescent Dyes/Probes
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .

HY-D2858A

8-arm-PEG-FITC (MW 20000)	Fluorescent Dyes/Probes
8-arm-PEG-FITC (MW 20000) is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em = 488/525 nm) .

HY-D2845C

4-arm-PEG-FITC (MW 20000)	Fluorescent Dyes/Probes
4-arm-PEG-FITC (MW 20000) is a fluorescent dye composed of FITC (HY-66019) and four-arm polyethylene glycol (4-Arm PEG). 4-arm-PEG-FITC (MW 20000) can be used to modify proteins, peptides and other materials with active groups (Ex/Em = 488/525 nm) .

HY-D2858B

8-arm-PEG-FITC (MW 40000)	Fluorescent Dyes/Probes
8-arm-PEG-FITC (MW 40000) is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG-FITC (MW 40000) can be used to modify proteins, peptides and other materials with active groups (Ex/Em = 488/525 nm) .

HY-D2858

8-arm-PEG-FITC (MW 10000)	Fluorescent Dyes/Probes
8-arm-PEG-FITC (MW 20000) is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG-FITC (MW 20000) can be used to modify proteins, peptides and other materials with active groups (Ex/Em = 488/525 nm) .

Cat. No.	Product Name	Type

HY-174358C

HOOC-PEG-COOH (MW 5000)	Drug Delivery
HOOC-PEG-COOH (MW 5000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 5000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358

HOOC-PEG-COOH (MW 1000)	Drug Delivery
HOOC-PEG-COOH (MW 1000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 1000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358D

HOOC-PEG-COOH (MW 10000)	Drug Delivery
HOOC-PEG-COOH (MW 10000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 10000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358E

HOOC-PEG-COOH (MW 20000)	Drug Delivery
HOOC-PEG-COOH (MW 20000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 20000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358H

HOOC-PEG-COOH (MW 40000)	Drug Delivery
HOOC-PEG-COOH (MW 40000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 40000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358A

HOOC-PEG-COOH (MW 2000)	Drug Delivery
HOOC-PEG-COOH (MW 2000) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 2000) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-174358B

HOOC-PEG-COOH (MW 3400)	Drug Delivery
HOOC-PEG-COOH (MW 3400) has two active carboxyl groups at both ends, which can selectively react with the amino groups in peptide coupling agents. HOOC-PEG-COOH (MW 3400) is a good cross-linking agent for PEGylation of proteins and peptides, nanoparticles and surface modification .

HY-W1123939

Silane-PEG-COOH (MW 1000)	Drug Delivery
Silane-PEG-COOH (MW 1000) can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1123939A

Silane-PEG-COOH (MW 2000)	Drug Delivery
Silane-PEG-COOH (MW 2000) can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1123939C

Silane-PEG-COOH (MW 5000)	Drug Delivery
Silane-PEG-COOH (MW 5000) can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1123939B

Silane-PEG-COOH (MW 3400)	Drug Delivery
Silane-PEG-COOH (MW 3400) can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1049075A

mPEG-pALD (MW 5000)

Drug Delivery

mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075C

mPEG-pALD (MW 20000)

Drug Delivery

mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075B

mPEG-pALD (MW 10000)

Drug Delivery

mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075E

mPEG-pALD (MW 2000)

Drug Delivery

mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075D

mPEG-pALD (MW 40000)

Drug Delivery

mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075H

mPEG-pALD (MW 3400)

Drug Delivery

mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075

mPEG-pALD (MW 1000)

Drug Delivery

mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-B2228

Proteinase, Aspergillus oryzae

Biochemical Assay Reagents

Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

Cat. No.	Product Name

HY-K2016

Protein Transfection Reagent 1 Publications Verification
MCE Protein Transfection Reagent is a cationic lipid mixture for complexation with proteins, peptides, antibodies and other biologically active molecules to allow their direct intracellular delivery.

Cat. No.	Product Name	Target	Research Area

HY-P99906

Sirexatamab DKN-01; LY-2812176	β-catenin	Cancer
Sirexatamab (DKN-01) is a humanized IgG4 monoclonal antibody that can bind to and neutralize circulating DKK1. Sirexatamab exhibits antitumor activity in tumor models expressing DKK1 .

HY-P99928

Efprezimod alfa	Transmembrane Glycoprotein	Cancer
Efprezimod alfa is a CD24 fusion protein. Efprezimod alfa can be used for various biochemical studies.

HY-P99907

Efgivanermin alfa	Inhibitory Antibodies	Cancer
Efgivanermin alfa is an active peptide. Efgivanermin alfa can be used for various biochemical studies.

HY-P99924

Efpegsomatropin	GHR	Others
Efpegsomatropin is a human growth hormone-Fc conjugate peptide. Efpegsomatropin can be used for various biochemical studies.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P1543

Exendin-3	Structural Classification Natural Products Animals Source classification	GLP Receptor Amylases GCGR
Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn.

HY-N1476

Heterophyllin B 4 Publications Verification	Structural Classification other families Pseudostellaria heterophylla (Miq.) Pax Classification of Application Fields Cyclopeptides Source classification Plants Disease Research Fields Caryophyllaceae Cancer	PI3K
Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. Heterophyllin B provides a novel strategy for the treatment of esophageal cancer .

HY-105088

Pexiganan MSI 78 free base	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial
Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections .

HY-N11140

Glu-Lys	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
Glu-Lys is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5700

SAAP Fraction 3	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer .

HY-P5670

Maximin 31	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 31 is an antimicrobial peptide derived from the toad brain. Maximin 31 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 37.5, 75 μg/mL, respectively .

HY-P5671

Maximin 32	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 32 is an antimicrobial peptide derived from the toad brain. Maximin 32 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 9.4, 18.8 μg/mL, respectively .

HY-P5672

Maximin 39	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 39 is an antimicrobial peptide derived from the toad brain. Maximin 39 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 18.8, 37.5 μg/mL, respectively .

HY-P5708

Adenoregulin Dermaseptin b2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Antibiotic Fungal Bacterial
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-P5666

Maximin 15	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 15 is an antimicrobial peptide derived from the toad brain. Maximin 15 is active against Staphylococcus aureus, Escherichia coli and Bacillus subtilis, with MIC values of 9.4, 18.8, 75 μg/mL, respectively .

HY-P5668

Maximin 28	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 28 is an antimicrobial peptide derived from the toad brain. Maximin 28 is active against Staphylococcus aureus, Escherichia coli and Bacillus subtilis, with MIC values of 4.7, 9.4, 75 μg/mL, respectively .

HY-N10583

Motuporin	Natural Products Microorganisms	Others
Motuporin is a cyclic peptide. Motuporin was initially isolated from T. swinhoei .

HY-N7122R

Thymopentin (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite	Endogenous Metabolite
Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .

HY-N7122

Thymopentin	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .

HY-N7122A

Thymopentin acetate	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .

HY-105088A

Pexiganan acetate MSI 78	Structural Classification Natural Products Animals Source classification	Bacterial
Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections .

HY-P0270

Magainin 2 Magainin II	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an *antimicrobial peptide* (AMP) isolated from the skin of the African clawed frog Xenopus laevis*. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active* against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-B1746R

Pyridoxamine 5′-phosphate (Standard)	Structural Classification Alkaloids Human Gut Microbiota Metabolites Source classification Pyridine Alkaloids Endogenous metabolite	Reference Standards Endogenous Metabolite
Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .

HY-P1902

Cardiotoxin Analog (CTX) IV (6-12) Maximum Cited Publications 7 Publications Verification	Cardiovascular Disease Natural Products Animals Source classification Disease Research Fields	Apoptosis
Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .

HY-P1902A

Cardiotoxin Analog (CTX) IV (6-12) TFA Maximum Cited Publications 7 Publications Verification	Structural Classification Pyrrole Alkaloids Animals Source classification Other Diseases Disease Research Fields	Apoptosis
Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .

HY-113513

5-HEPE	Microorganisms Source classification	Others
5(S)-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.

Cat. No.	Product Name	Chemical Structure

HY-14184S

Macitentan-d4
Macitentan-d₄ is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) .

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-P4229

([D8]Val7,10)-C-Peptide (human)
([D8]Val7,10)-C-Peptide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10324

TAT-p16
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

HY-B0477AS2

Quinapril-d4

Quinapril-d₄ (CI-906-d₄) is deuterium labeled Quinapril. Quinapril is a potent, orally active, non-peptide and nonsulfhydryl inhibitor of angiotensin-converting enzyme (ACE). Quinapril specifically interrupts the conversion of angiotensin I to angiotensin II in both plasma and tissue. Quinapril is enzymatically hydrolyzed to a pharmacologically active diacid form quinaprilat. Quinapril is efficacious in hypertensive models .

HY-32709S

Telcagepant-d8
Telcagepant-d₈ (MK-0974-d₈) is deuterium labeled Telcagepant. Telcagepant (MK-0974) is an orally active *calcitonin gene-related peptide* (CGRP) receptor antagonist with K_i**s of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively.

HY-W751574

Elagolix-d6 sodium
Elagolix-d₆ (sodium) (NBI-56418-d₆ (sodium)) is deuterium labeled Elagolix sodium. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .

HY-10119S

Vorapaxar-d5
Vorapaxar-d₅ is deuterated labeled Vorapaxar (HY-10119). Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (K_i=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .

HY-12366S

Ubrogepant-d5

Ubrogepant-d₅ (MK-1602-d₅) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine .

HY-B1190S

Cefadroxil-d4 hydrate

Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil hydrate (HY-B1190A). Cefadroxil hydrate is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil hydrate inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil hydrate is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil hydrate has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .

HY-B1190S2

Cefadroxil-13C6

Cefadroxil- ¹³C₆ (BL-S 578- ¹³C₆) is ¹³C labeled Cefadroxil (HY-B1190). Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .

Cat. No.	Product Name		Classification

HY-106203A

Crinecerfont hydrochloride SSR-125543 hydrochloride		Alkynes
Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research . Crinecerfont (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-106203

Crinecerfont SSR-125543		Alkynes
Crinecerfont (SSR-125543) is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research . Crinecerfont is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-106203B

(R)-Crinecerfont (R)-SSR-125543		Alkynes
(R)-Crinecerfont is the R-enantiomer of Crinecerfont (HY-106203). Crinecerfont (SSR-125543) is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research. Crinecerfont is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

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