2. GPCR/G Protein
  3. GLP Receptor
  4. GLP-1R modulator-1

GLP-1R modulator-1 (Compound 384) is an orally active, potent selective glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R modulator-1 activates G-protein coupled signaling, elevates intracellular cAMP levels, promotes insulin secretion, delays gastric emptying and suppresses appetite. GLP-1R modulator-1 is promising for research of type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).

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GLP-1R modulator-1

GLP-1R modulator-1 Chemical Structure

CAS No. : 2978244-71-0

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GLP-1R modulator-1 Related Antibodies

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Description

GLP-1R modulator-1 (Compound 384) is an orally active, potent selective glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R modulator-1 activates G-protein coupled signaling, elevates intracellular cAMP levels, promotes insulin secretion, delays gastric emptying and suppresses appetite. GLP-1R modulator-1 is promising for research of type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH)[1].

Molecular Weight

733.23

Formula

C41H38ClFN6O4
CAS No.
SMILES

C[C@@]1(C2=C(C=C(C=C2)Cl)F)OC3=C(C4=CCN(CC5=NC6=CC(NC(C7=CC(C)=C(NN=C8C)C8=C7)=O)=CC=C6N5C[C@@H]9CCO9)CC4)C=CC=C3O1
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Purity & Documentation
References
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GLP-1R modulator-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GLP-1R modulator-12978244-71-0GLP Receptororally activeGLP-1RcAMPinsulin secretiontype 2 diabetesobesityNASHInhibitorinhibitorinhibit

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