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O2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Linker (4) Adenylate Cyclase (1) Akt (1) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (1) Amyloid-β (6) Apoptosis (19) Aquaporin (1) Autophagy (2) Bacterial (7) Beta-secretase (1) Biochemical Assay Reagents (24) Calcium Channel (3) CaMK (1) Carbonic Anhydrase (2) Caspase (4) CDK (1) Cholinesterase (ChE) (9) Complement System (1) COX (1) DNA/RNA Synthesis (8) Drug Derivative (1) Drug Intermediate (2) Drug Metabolite (1) EGFR (2) Endogenous Metabolite (22) Epigenetic Reader Domain (1) ERK (4) Ferroptosis (1) Fluorescent Dye (20) Fungal (3) HDAC (2) Heme Oxygenase (HO) (1) Histamine Receptor (1) Histone Acetyltransferase (1) HIV Protease (1) Huntingtin (3) iGluR (1) Influenza Virus (3) Insecticide (1) Interleukin Related (1) Isotope-Labeled Compounds (11) Keap1-Nrf2 (4) Liposome (1) LOX-1 (1) Melanocortin Receptor (4) mGluR (1) Mitochondrial Metabolism (2) Monoamine Oxidase (4) mTOR (4) nAChR (2) NADPH Oxidase (2) Necroptosis (1) Neurokinin Receptor (3) NF-κB (3) NO Synthase (1) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (63) p38 MAPK (2) Parasite (3) PARP (1) Phosphatase (1) Phosphodiesterase (PDE) (1) Photosensitizer (2) Phytohormone (1) PKC (1) PPAR (2) PROTAC Linkers (1) PROTACs (1) Pyroptosis (1) Reactive Oxygen Species (ROS) (49) Reference Standards (8) Reverse Transcriptase (1) ROS Kinase (1) Ser/Thr Protease (1) Sirtuin (2) Tau Protein (1) Toll-like Receptor (TLR) (1) Tyrosinase (1) URAT1 (1) VD/VDR (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (96) Cardiovascular Disease (20) Endocrinology (2) Infection (11) Inflammation/Immunology (45) Metabolic Disease (32) Neurological Disease (37)
Click Chemistry:	ADC Synthesis (1) Labeling and Fluorescence Imaging (1) Azide (8) Alkynes (3)
Oligonucleotides:	A (21) Nucleosides and their Analogs (61) C (7) U (19) G (9) I (5) Antisense Oligonucleotides (4)

284

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-402383

O-(((2R,3S,5R)-5-(5-Bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) O,S-dihydrogen phosphorothioate	Biochemical Assay Reagents	Others
O-(((2R,3S,5R)-5-(5-Bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) O,S-dihydrogen phosphorothioate is a biological molecule.

HY-W012313

2,2'-Anhydrouridine 2,2'-Cyclouridine; O2,2'-Cyclouridine	Drug Intermediate Nucleoside Antimetabolite/Analog	Others
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a nucleoside analog. 2,2'-Anhydrouridine is an important intermediate in the synthesis of other nucleoside-related compounds ^[2].

HY-159854

C14-O2	Liposome	Cancer
C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .

HY-P1012

[Sar9,Met(O2)11]-Substance P	Neurokinin Receptor	Neurological Disease Endocrinology
[Sar9,Met(O2)11]-Substance P is a tachykinin NK₁ receptor selective agonist.

HY-P1012A

[Sar9,Met(O2)11]-Substance P TFA	Neurokinin Receptor	Neurological Disease Endocrinology
[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK₁ receptor selective agonist.

HY-P2902

Glucose oxidase 3 Publications Verification	Endogenous Metabolite	Cancer
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O₂) to produce hydrogen peroxide (H₂O₂) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation ^[2] .

HY-W721191

O-2-Amino-2-methylpropyl bilastine-d6	Isotope-Labeled Compounds	Others
O-2-Amino-2-methylpropyl bilastine-d₆ is the deuterium labeled O-tert-Butyl-dimethylsilyl curcumin.

HY-W073314

2,2,2-Trifluoroethoxyamine hydrochloride O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride	Biochemical Assay Reagents	Others
2,2,2-Trifluoroethoxyamine (O-(2,2,2-Trifluoroethyl)hydroxylamine) hydrochloride can be used as an oxime reactant for coupling reactions with reducing sugars .

HY-P3782

(Met(O2)35)-Amyloid β-Protein (1-42)	Amyloid-β	Others
(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide .

HY-N7161

*3-O-(2'E,4'E-Decadienoyl)-ingenol*	Others	Others
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC₅₀s of 8.22 μM and 6.67 μM, respectively .

HY-115386

MitoTEMPOL	Reactive Oxygen Species (ROS)	Cancer
MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2 ^-to H2O2 .

HY-119038

ML-7	Endogenous Metabolite	Cardiovascular Disease
ML-7 is a myosin light chain kinase inhibitor with the activity to inhibit superoxide anion (O(2)(-)) release in human neutrophils. ML-7 can affect the activity of neutrophils independently of myosin light chain kinase. ML-7 inhibits the extracellular O(2)(-) release of stimulated cells, but has no effect on the intracellular O(2)(-) production. ML-7 also strongly inhibits the binding of the intracellular compartment of oxide production to the cell membrane, indicating that it plays a key role in stimulated neutrophils. At the same time, ML-7 protects cardiac function from ischemia/reperfusion injury .

HY-D1156

HKSOX-1m (5/6-mixture)	Reactive Oxygen Species (ROS) Fluorescent Dye	Others
HKSOX-1m (5/6-mixture) is a O₂ fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂ over a broad range of pH, strong oxidants, and abundant reductants found in cells .

HY-D1156A

HKSOX-1m (5/6-mixture) hydrobromide 1 Publications Verification	Reactive Oxygen Species (ROS) Fluorescent Dye	Others
HKSOX-1m (5/6-mixture) hydrobromide is a O₂ fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂ over a broad range of pH, strong oxidants, and abundant reductants found in cells .

HY-117457

BPIC	DNA/RNA Synthesis	Cancer
BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals .

HY-139701

NI-Pano	HDAC	Cancer
NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor. NI-Pano (CH-03) is reduced in an O₂-dependent manner to release panobinostat.

HY-W013794

Salcomine N,N′-Bis(salicylidene)ethylenediaminocobalt(II)	Influenza Virus	Infection
Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O₂ and oxidation catalysts. Salcomine has anti-influenza virus activity .

HY-125575

FC11409B	Carbonic Anhydrase	Cancer
FC11409B is an ureido-sulfamate carbonic anhydrase IX (CAIX) inhibitor. FC11409B inhibits proliferation and migration of breast cancer cell lines in both hypoxic (0.5% O₂) and normoxic conditions (21% O₂). FC11409B also inhibits 3D spheroid of breast cancer subtypes invasion. FC11409B is promising for research of breast and ovarian cancers .

HY-10535

Evofosfamide 5+ Cited Publications TH-302	Apoptosis	Cancer
Evofosfamide (TH-302) is a hypoxia-activated proagent with IC₅₀ of 10 μM and 1000 μM in hypoxia (N₂) and normoxia (21% O₂), respectively.

HY-B1776

Spermidine 5+ Cited Publications	Endogenous Metabolite	Metabolic Disease
Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H₂O₂ and O₂ ^.- contents .

HY-B1776A

Spermidine hydrochloride 5+ Cited Publications	Endogenous Metabolite	Metabolic Disease
Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H₂O₂ and O₂ ^.- contents .

HY-13619

Efaproxiral 1 Publications Verification RSR13	Reactive Oxygen Species (ROS)	Cancer
Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-161502

DHX-SP	Fluorescent Dye	Others
DHX-SP is a fluorescent probe, which visualizes superoxide anion (O₂ ^·–) and peroxynitrite (ONOO ^–) during ferroptosis of PC12 cells and in the Parkinson’s disease model .

HY-13619A

Efaproxiral sodium 1 Publications Verification RSR13 sodium	Reactive Oxygen Species (ROS)	Cancer
Efaproxiral sodium (RSR13 sodium) is a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy.

HY-150175

HKSOX-1	Fluorescent Dye	Inflammation/Immunology
HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O₂ ^•−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O₂ ^•−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O₂ ^•− roles in inflammation, mitochondrial stress, and other physiological processes .

HY-15475

UK-5099 Maximum Cited Publications 38 Publications Verification PF-1005023	Mitochondrial Metabolism	Cancer
UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O₂ consumption with an IC₅₀ of 50 nM.

HY-N0501

11-oxo-mogroside V	Reactive Oxygen Species (ROS)	Metabolic Disease
11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O₂ ^-, *H₂O₂* and OH) with EC₅₀* of 4.79, 16.52, and 146.17 μg/mL, respectively.

HY-B1776S

Spermidine-d6	Endogenous Metabolite	Metabolic Disease
Spermidine-d₆ is the deuterium labeled Spermidine . Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents ^[2].

HY-B1776AS

Spermidine-d8 hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Spermidine-d₈ (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-109110

Avasopasem manganese GC-4419; M-40419	Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O₂ ^- to hydrogen peroxide (H₂O₂),* arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .

HY-B1776AS1

Spermidine-13C4 hydrochloride 1 Publications Verification	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Spermidine- ¹³C₄ (hydrochloride) is the ¹³C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-B1776R

Spermidine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Spermidine (Standard) is the analytical standard of Spermidine. This product is intended for research and analytical applications. Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents .

HY-B1776AR

Spermidine hydrochloride (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Spermidine (hydrochloride) (Standard) is the analytical standard of Spermidine (hydrochloride). This product is intended for research and analytical applications. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-13619S

Efaproxiral-d6	Isotope-Labeled Compounds Reactive Oxygen Species (ROS)	Cancer
Efaproxiral-d₆ is the deuterium labeled Efaproxiral. Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy ^[2].

HY-13619R

Efaproxiral (Standard)	Reactive Oxygen Species (ROS)	Cancer
Efaproxiral (Standard) is the analytical standard of Efaproxiral. This product is intended for research and analytical applications. Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-N3464

Isopedicin	Phosphodiesterase (PDE)	Metabolic Disease
Isopedicin potently and concentration-dependently inhibits superoxide anion (O2 U?) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. Isopedicin increases cAMP formation and PKA activity in FMLP-activated cells by inhibiting phosphodiesterase (PDE) activity .

HY-B0019

Azasetron (Rac)-SENS-401 free base	5-HT Receptor	Neurological Disease
Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .

HY-135849C

Catalase, trichoderma reesei	Reactive Oxygen Species (ROS)	Cancer
Catalase, Trichoderma reesei, is a catalase enzyme that catalyzes the decomposition of hydrogen peroxide (H₂O₂) into water (H₂O) and oxygen (O₂). Catalase is mainly present in peroxisomes and shuttles between the cytoplasm and peroxisomes, thereby protecting cells from oxidative damage. Abnormal activity or expression of catalase is closely related to the occurrence and development of cancer .

HY-116694

Digallic acid	Apoptosis Reactive Oxygen Species (ROS) Reverse Transcriptase Xanthine Oxidase URAT1	Infection Metabolic Disease Inflammation/Immunology Cancer
Digallic acid is an antioxidant, antimutagenic, antigenotoxic, and anti-hyperuricemic compound. Digallic acid is a reverse transcriptase and XOD, URAT1 (IC₅₀: 5.34 μM) inhibitor. Digallic acid scavenges DPPH· and O2·− radicals. Digallic acid induces apoptosis. Digallic acid can be isolated from the fruits of Pistascia lentiscus ^[2] .

HY-B0464A

Hydralazine	Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology Cancer
Hydralazine is a orally active antihypertensive agent, reduces peripheral resistance directly by relaxing the smooth muscle cell layer in arterial vessel. Hydralazine has antioxidant activity, as well as inhibits reactive oxygen species (ROS) release and O₂ ^·- generation with an IC₅₀ value of 9.53 mM and 1.19 mM, respectively ^[2].

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Others	Inflammation/Immunology
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

HY-W112239

BDPI	Reactive Oxygen Species (ROS) Fluorescent Dye	Cancer
BDPI is the a BODIPY derivative. BDPI reveals a high O₂ quantum yield and exhibits phototoxicity that inhibits HeLa with an IC₅₀ of 0.6 µg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models .

HY-108298

Perfluorodecalin PP 5; Perfluorodecahydronaphthalene	Biochemical Assay Reagents	Others
Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears ^[2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O₂-carrier and used as artificial blood . Perfluorodecalin enhances bone regeneration and cell viability .

HY-N0501R

11-oxo-mogroside V (Standard)	Reference Standards Reactive Oxygen Species (ROS)	Metabolic Disease
11-oxo-mogroside V (Standard) is the analytical standard of 11-oxo-mogroside V. This product is intended for research and analytical applications. 11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2-, H2O2 and OH) with EC₅₀* of 4.79, 16.52, and 146.17 μg/mL, respectively.

HY-120167

YM-44778	Neurokinin Receptor	Neurological Disease Inflammation/Immunology
YM-44778 is a neurokinin receptor antagonist. The _pK_i values for NK1, NK2 and NK3 are 8.08, 8.55 and 8.24, respectively. YM-44778 inhibits the increase of bladder pressure induced by substance [Sar9,Met(O2)11] -P (HY-P1012) in anestheticized rats .

HY-W777959

Azasetron Hydrochloride-13C,d3	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Azasetron Hydrochloride- ¹³C,d₃ is the deuterium and ¹³C-labeled Azasetron (HY-B0019). Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .

HY-W010417

4-Thiouracil	Reactive Oxygen Species (ROS)	Others
4-Thiouracil is a thionucleobase with cytostatic properties. 4-Thiouracil can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts. 4-Thiouracil can also act as a strong ultraviolet A (UVA) photosensitizer, providing a source of the reactive oxygen species of O₂. 4-Thiouracil is promising for research of photocross linking, photodamage, as well as photodynamic therapy .

HY-129109

NBD-Pen	Fluorescent Dye	Inflammation/Immunology Cancer
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λ_ex: 470 nm, λ_em: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H₂O₂, ClO ^-, O₂ ^-∙, and ∙OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .

HY-170938

AChE-IN-82	Cholinesterase (ChE) Monoamine Oxidase Beta-secretase COX LOX-1	Neurological Disease
AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-82 inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC₅₀s of 0.072, 9.81, 14.52, 0.024, 2.42 μM, respectively. AChE-IN-82 inhibits COX-1, *COX-2* and 5-LOX with IC₅₀s of 60.41, 0.187, 0.18 μM, respectively. AChE-IN-82 shows an excellent neuroprotective effect by significantly reducing oxidative stress induced by H₂ O₂ .

HY-W051271

Titanium(IV) oxide Titanium dioxide	Photosensitizer Reactive Oxygen Species (ROS)	Others
Titanium(IV) oxide is a photosensitizer and photocatalyst. Titanium(IV) oxide can be used as a pharmaceutical excipient such as a flow aid, coating agent, sunscreen, colorant, etc. Pharmaceutical excipients or pharmaceutical excipients refer to other chemical substances used in the pharmaceutical process other than the drug ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations that can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism and elimination (ADME) process of co-administered drugs. Titanium(IV) oxide can use light energy to generate electron-hole pairs to degrade pollutants. Photons excite electrons in TiO₂ to generate active oxygen species (such as ·OH and ·O₂ ^-), thereby oxidizing and mineralizing pollutants such as organic compounds and heavy metals. TiO₂ can be used in the research of environmental remediation fields such as water treatment, air purification and self-cleaning materials ^[2] .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012313

2,2'-Anhydrouridine 2,2'-Cyclouridine; O2,2'-Cyclouridine	Infection Classification of Application Fields Disease Research Fields	Drug Intermediate Nucleoside Antimetabolite/Analog
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a nucleoside analog. 2,2'-Anhydrouridine is an important intermediate in the synthesis of other nucleoside-related compounds ^[2].

HY-B1776

Spermidine 5+ Cited Publications	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H₂O₂ and O₂ ^.- contents .

HY-B1776A

Spermidine hydrochloride 5+ Cited Publications	Structural Classification Natural Products other families Animals Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H₂O₂ and O₂ ^.- contents .

HY-N0501

11-oxo-mogroside V	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research	Reactive Oxygen Species (ROS)
11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O₂ ^-, *H₂O₂* and OH) with EC₅₀* of 4.79, 16.52, and 146.17 μg/mL, respectively.

HY-B1776R

Spermidine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Spermidine (Standard) is the analytical standard of Spermidine. This product is intended for research and analytical applications. Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents .

HY-N7161

*3-O-(2'E,4'E-Decadienoyl)-ingenol*	Structural Classification Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants	Others
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC₅₀s of 8.22 μM and 6.67 μM, respectively .

HY-B1776AR

Spermidine hydrochloride (Standard)	Structural Classification Natural Products other families Animals Source classification Plants Endogenous metabolite	Reference Standards Endogenous Metabolite
Spermidine (hydrochloride) (Standard) is the analytical standard of Spermidine (hydrochloride). This product is intended for research and analytical applications. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-N3464

Isopedicin	Structural Classification Flavonoids Flavonones Source classification Plants Annonaceae Fissistigma oldhamii (Hemsl.) Merr.	Phosphodiesterase (PDE)
Isopedicin potently and concentration-dependently inhibits superoxide anion (O2 U?) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. Isopedicin increases cAMP formation and PKA activity in FMLP-activated cells by inhibiting phosphodiesterase (PDE) activity .

HY-116694

Digallic acid	Structural Classification Pistacia lentiscus var. Chia Source classification Phenols Polyphenols Plants Anacardiaceae	Apoptosis Reactive Oxygen Species (ROS) Reverse Transcriptase Xanthine Oxidase URAT1
Digallic acid is an antioxidant, antimutagenic, antigenotoxic, and anti-hyperuricemic compound. Digallic acid is a reverse transcriptase and XOD, URAT1 (IC₅₀: 5.34 μM) inhibitor. Digallic acid scavenges DPPH· and O2·− radicals. Digallic acid induces apoptosis. Digallic acid can be isolated from the fruits of Pistascia lentiscus ^[2] .

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Quinones Structural Classification Anthraquinones Polygonaceae Source classification Rheum rhabarbarum Linnaeus Plants	Others
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

HY-N0501R

11-oxo-mogroside V (Standard)	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants	Reference Standards Reactive Oxygen Species (ROS)
11-oxo-mogroside V (Standard) is the analytical standard of 11-oxo-mogroside V. This product is intended for research and analytical applications. 11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2-, H2O2 and OH) with EC₅₀* of 4.79, 16.52, and 146.17 μg/mL, respectively.

HY-N2153

*Apigenin-7-O-(2G-rhamnosyl)gentiobioside*	Structural Classification Flavonoids Classification of Application Fields Flavones Source classification Other Diseases Phenols Polyphenols Umbelliferae Plants Baccharis sarothroides A.Gray Disease Research Fields	Others
Apigenin-7-O-(2G-rhamnosyl)gentiobioside is a flavone glycosides from Lonicera gracilipes var. glandulosa .

HY-N11538

*Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside*	Structural Classification Flavonoids Classification of Application Fields Polygonaceae Source classification Plants Other Flavonoids Inflammation/Immunology Disease Research Fields Polygonum capitatum Buch.-Ham. ex D. Don Prodr	Others
Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside is a orally active phenolic compound that can be isolated from the Geranium species. Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside has anti-inflammatory activities and has potential application in edema and aortic endothelium-dependent relaxation injury .

HY-N7166

*3-O-(2'E,4'Z-Decadienoyl)ingenol*	Structural Classification Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants	Complement System
3-O-(2'E,4'Z-Decadienoyl)ingenol is a natural diterpene that exhibits significant anticomplement activity with an IC₅₀ of 89.5 μM .

HY-N7168A

*3-O-(2'E ,4'Z-Decadienoyl)-20-O-acetylingenol*	Structural Classification Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants	Others
3-O-(2'E ,4'Z-Decadienoyl)-20-O-acetylingenol (compound 6) is a diterpene that can be isolated from Euphorbia kansui. 3-O-(2'E ,4'Z-Decadienoyl)-20-O-acetylingenol shows cleavage inhibition activity of individual Xenopus cells at the blastular stage .

HY-N7168

*3-O-(2'E ,4'E-Decadienoyl)-20-O-acetylingenol*	Structural Classification Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants	Others
3-O-(2'E ,4'E-Decadienoyl)-20-O-acetylingenol is a ingenol-type diterpenoid that contains a 2,4-decadienoyloxy group .

HY-N5119

*Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside*	Flavonoids other families Classification of Application Fields Flavones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside is a natural glycoside that could be found in Camellia oleifera seeds .

HY-N9529

*Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside)*	Flavonols Flavonoids Classification of Application Fields Leguminosae Source classification Clitoria ternatea Linn. Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside) is a flavonoid glycoside compound .

HY-N13116

*3-O-(2",3"-Dimethylbutanoyl)-13-O-decanoylingenol*	Structural Classification Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants	Parasite
3-O-(2",3"-Dimethylbutanoyl)-13-O-decanoylingenol (compound 2) is a diterpenoid with antinematode activity, which can be isolated from Euphorbia kansui .

HY-N13542

*Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside*	Structural Classification Melastomataceae Flavonoids Melastoma dodecandrum Lour. Source classification Plants Other Flavonoids	Others
Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product .

HY-N8946

*1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone*	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae Piptanthus nepalensis (Hook.) D. Don	Others
1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone is a Sesquiterpenoids product that can be isolated from the flower heads of Inula britannica. .

HY-N10784

*Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside*	Triterpenes Structural Classification Terpenoids Source classification Plants Fagaceae Castanea crenata Siebold et Zuccarini	Insecticide
Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside is a acylated keampferol glucoside. Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside can be isolated from the leaves of O. dentata, acts as a repellent against a fouling organism, the blue mussel M. edulis .

HY-N15631

*Apigenin-4'-O-(2",6"-di-O-coumaroyl)-β-D-glucopyranoside*	Lycopodiaceae Structural Classification Source classification Phenols Polyphenols Palhinhaea cernua (L.) Vasc. et Franco Plants	Others
Apigenin-4'-O-(2",6"-di-O-coumaroyl)-β-D-glucopyranoside is a flavonoid compound that can be isolated from the methanol extract of Lycopodium cernuum .

HY-N9676

*Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside*	Structural Classification Flavonoids Flavones Source classification Quercus dentata Thunb. Plants Fagaceae	Others
Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside is a flavonoid compound that can be isolated from Quercus dentata. Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside suppresses the superoxide generation induced by arachidonic acid .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Flavonoids Classification of Application Fields Ginkgoaceae Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Ginkgo biloba	Others
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

HY-N3117

Paeonilactone B (+)-Paeonilactone B	Structural Classification Natural Products Paeonia lactiflora Pall. Source classification Plants Paeoniaceae	Others
Paeonilactone B is a monoterpene with neuroprotective effect against oxidative stress. Paeonilactone B protects rat cortical cells against H₂O₂-induced neurotoxicity .

HY-N1318

Salvigenin 5 Publications Verification Psathyrotin	Structural Classification Monophenols Flavonoids other families Neurological Disease Classification of Application Fields Flavones Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Autophagy Apoptosis ROS Kinase
Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H₂O₂-induced cell apoptosis ^[2].

HY-N2190

Hederagenin 28-O-beta-D-glucopyranosyl ester	Cardiovascular Disease Triterpenes Structural Classification Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Araliaceae	Others
Hederagenin 28-O-beta-D-glucopyranosyl ester, a triterpenoid saponin isolated from Ilex cornuta, exhibits protective effects against H₂O₂-induced myocardial cell injury .

HY-N5045

Jionoside A1	Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Scrophulariaceae Phenylpropanoids Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Disease Research Fields Inflammation/Immunology	Others
Jionoside A1 isolated from Radix Rehmanniae Praeparata displays dose dependent immune-enhancement activity and possesses moderate protective activities on H₂O₂-treated SH-SY5Y cells .

HY-N7627

Regaloside C	Cardiovascular Disease Classification of Application Fields Simple Phenylpropanols Gramineae Source classification Secale cereale Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields	Others
Regaloside C is a glycerol glucoside isolated from the bulbs of Lilium genus with anti-inflammatory activities. Regaloside C has cardiomyocyte protective activity by protecting the mitochondria in H₂O₂-induced heart H9C2 cells .

HY-125919

Vulpinic acid	Source classification Plants Endogenous metabolite	Reactive Oxygen Species (ROS) Bacterial Endogenous Metabolite
Vulpinic acid, a lichen metabolite, decreases H₂O₂-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research ^[2].

HY-N2410

N-trans-Feruloyltyramine N-feruloyltyramine; Moupinamide	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Phenols Polyphenols Piperaceae Plants Inflammation/Immunology Disease Research Fields Piper nigrum Linn.	Reactive Oxygen Species (ROS) Apoptosis
N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid, is a potent antioxidant. N-trans-Feruloyltyramine improves H₂O₂-induced intracellular ROS generation and decreases apoptosis. N-trans-Feruloyltyramine has the potential for oxidative stress-related neurodegenerative conditions and cancer research ^[2].

HY-N2565

Rosamultin	Infection Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Rosaceae Potentilla anserina Linn. Plants Disease Research Fields	HIV Protease Apoptosis
Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina?L. Rosamultin has inhibitory effects against HIV-1 protease . Rosamultin has the potential for treating H₂O₂-induced oxidative stress injury through its antioxidant and antiapoptosis effects ^[2].

HY-N15711

Ganoleucoin R	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Reactive Oxygen Species (ROS)
Ganoleucoin R is a triterpenoid compound that can be isolated from Ganoderma leucocontextum. Ganoleucoin R exerts a protective effect against H₂O₂-induced oxidative damage and can promote neurite outgrowth in PC12 cells. Ganoleucoin R possesses neuroprotective and neurogenic activities, and can be used in the research of neurodegenerative diseases .

HY-N0115

Gastrodin Maximum Cited Publications 17 Publications Verification Gastrodine	Structural Classification Natural Products Gastrodia elata Bl. Neurological Disease Classification of Application Fields Anti-aging Orchidaceae Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Apoptosis Ferroptosis
Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H₂O₂-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia ^[2] .

HY-N5021

Anhydrosafflor yellow B AHSYB	Quinones Simple Phenylpropanols Carthamus tinctorius L. Source classification Phenols Polyphenols Benzene Quinones Phenylpropanoids Plants Compositae	Others
Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H₂O₂-induced cytotoxicity in cultured PC12 cells and primary neuronal cells .

HY-N7880

Salvianolic acid Y	Structural Classification Classification of Application Fields Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Source classification Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Cancer	Reactive Oxygen Species (ROS)
Salvianolic acid Y is a phenolic acid with the same planar structure as Salvianolic acid B. Salvianolic acid Y rescues cell injury by H₂O₂ .

HY-N2410R

N-trans-Feruloyltyramine (Standard) N-feruloyltyramine (Standard); Moupinamide (Standard)	Alkaloids Structural Classification Other Alkaloids Source classification Phenols Polyphenols Piperaceae Plants Piper nigrum Linn.	Reference Standards Reactive Oxygen Species (ROS) Apoptosis
N-trans-Feruloyltyramine (Standard) is the analytical standard of N-trans-Feruloyltyramine. This product is intended for research and analytical applications. N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid, is a potent antioxidant. N-trans-Feruloyltyramine improves H2O2-induced intracellular ROS generation and decreases apoptosis. N-trans-Feruloyltyramine has the potential for oxidative stress-related neurodegenerative conditions and cancer research ^[2].

HY-N2442

Methylophiopogonone B	Structural Classification Natural Products other families Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	Reactive Oxygen Species (ROS)
Methylophiopogonone B, a homoisoflavonoidal compound that could be isolated from Ophiopogonis Tiber, could scavenge •OH and H₂O₂ in vitro to a certain extent ^[2].

HY-N0615

Notoginsenoside R1 2 Publications Verification Sanchinoside R1; Sanqi glucoside R1	Triterpenes Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields Araliaceae	Amyloid-β Apoptosis
Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H₂O₂-induced oxidative damage in PC12 cells ^[2] .

HY-N0540

Cynaroside 5+ Cited Publications Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Centaurea ornata Phenols Polyphenols Umbelliferae Plants Disease Research Fields	Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal
Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-121174

Alaternin Catharticin	Structural Classification Flavonoids Source classification Plants Rhamnaceae Rhamnus saxatilis X. H. Song	NO Synthase CDK Tyrosinase Reactive Oxygen Species (ROS)
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO₄/H₂O₂) with an IC₅₀ value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC₅₀ value of 4.02 μM .

HY-N7697E

Chitotriose trihydrochloride	Structural Classification Polysaccharides Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Others
Chitotriose trihydrochloride is an orally active chitooligosaccharide with antioxidant activities. Chitotriose trihydrochloride inhibits hydroxylation of benzoate to salicylate by H₂O₂ in the presence of Cu ²⁺ (IC₅₀ value of 80 μM) .

HY-N13174

Peanut procyanidin A	Structural Classification Arachis hypogaea L. Leguminosae Source classification Phenols Polyphenols Plants	Reactive Oxygen Species (ROS) Apoptosis
Peanut procyanidin A is a type of A-type procyanidin that can be extracted from peanut skins. Peanut procyanidin A can protect prostate DU145 cells from *H₂O₂*-induced oxidative stress damage through the MAPKs signaling pathway, alleviate cell cycle arrest, and reduce cell apoptosis. Peanut procyanidin A can also regulate gut microbiota and metabolism in mice with DSS (HY-116282)-induced ulcerative colitis ^[2].

HY-N10277

Inubritannolide A	Natural Products other families Source classification Plants	Others
Inubritannolide A displays slight strong neuroprotective potency against different types of neuronal cells mediated by various inducers including H₂O₂, 6-hydroxydopamine (6-OHDA), and lipopolysaccharide (LPS).

HY-N0540R

Cynaroside (Standard) Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)	Structural Classification Flavonoids Flavones Centaurea ornata Phenols Polyphenols Umbelliferae Plants	Apoptosis DNA/RNA Synthesis Parasite Bacterial Influenza Virus Fungal Reference Standards
Cynaroside (Standard) is the analytical standard of Cynaroside. This product is intended for research and analytical applications. Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC₅₀ of 32 nM. Cynaroside also is a promising inhibitor for H₂O₂-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .

HY-N0615R

Notoginsenoside R1 (Standard) Sanchinoside R1 (Standard); Sanqi glucoside R1 (Standard)	Triterpenes Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Source classification Plants Araliaceae	Reference Standards Amyloid-β Apoptosis
Notoginsenoside R1 (Standard) is the analytical standard of Notoginsenoside R1. This product is intended for research and analytical applications. Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells ^[2] .

HY-N8788

Baicalein 7-O-β-D-ethylglucuronide	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Baicalein 7-O-β-D-ethylglucuronide is a natural flavone glycoside that can be extracted from Scutellaria baicalensis Georgi. Baicalein 7-O-β-D-ethylglucuronide has antioxidant activity. Baicalein 7-O-β-D-ethylglucuronide inhibits FeSO₄-Cys-induced lipid peroxidation of liver homogenate. Baicalein 7-O-β-D-ethylglucuronide also shows strong cytoprotective effect on H₂O₂-induced oxidative damage of human umbilical vein endothelial cells ^[2].

HY-N2627

Isorhamnetin 3-O-robinobioside	Structural Classification Flavonoids Cactaceae Flavones Source classification Opuntia ficus-indica (L.) Mill. Plants	Others
Isorhamnetin 3-O-robinobioside is a flavonoid compound. Isorhamnetin shows a protective effect against lipid peroxidation induced by H₂O₂. Isorhamnetin 3-O-robinobioside also inhibits the genotoxicity induced by hydroxyl radicals .

HY-N2203

Vitexin2''-O-p-coumarate	Structural Classification Flavonoids other families Classification of Application Fields Flavones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ ^[2].

Cat. No.	Product Name	Chemical Structure

HY-B1776S

Spermidine-d6
Spermidine-d₆ is the deuterium labeled Spermidine . Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents ^[2].

HY-B1776AS

Spermidine-d8 hydrochloride
Spermidine-d₈ (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-B1776AS1

Spermidine-13C4 hydrochloride 1 Publications Verification
Spermidine- ¹³C₄ (hydrochloride) is the ¹³C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-W721191

O-2-Amino-2-methylpropyl bilastine-d6
O-2-Amino-2-methylpropyl bilastine-d₆ is the deuterium labeled O-tert-Butyl-dimethylsilyl curcumin.

HY-13619S

Efaproxiral-d6
Efaproxiral-d₆ is the deuterium labeled Efaproxiral. Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy ^[2].

HY-W777959

Azasetron Hydrochloride-13C,d3

Azasetron Hydrochloride- ¹³C,d₃ is the deuterium and ¹³C-labeled Azasetron (HY-B0019). Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .

HY-N7092S21

D-Fructose-18O-2
D-Fructose- ¹⁸O-2 is the ¹⁸O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants .

HY-B0389S31

D-Glucose-18O-2
D-Glucose- ¹⁸O-2 is the ¹⁸O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule

HY-N0486S10

L-Leucine-18O2
L-Leucine- ¹⁸O₂ is the ¹⁸O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

HY-W777322

3,4-Dihydroxybenzeneacetic acid-13C,18O2
3,4-Dihydroxybenzeneacetic acid- ¹³C, ¹⁸O₂ is the ¹³C- and ¹⁸O-labeled labeled 3,4-Dihydroxybenzeneacetic acid (HY-W001080). 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.

HY-166873S

Fluvoxamine-d3
Fluvoxamine-d₃ is deuterium labeled (Z)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)pentan-1-one O-(2-aminoethyl) oxime (Fluvoxamine Impurity) .

HY-W738271

Veratryl alcohol-13C

Veratryl alcohol- ¹³C (3,4-Dimethoxybenzyl alcohol- ¹³C) is the ¹³C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy ^[2] .

HY-W768213

2'-Deoxyguanosine monohydrate-13C5

2'-Deoxyguanosine monohydrate- ¹³C₅ is the ¹³C-labeled 2'-Deoxyguanosine monohydrate (HY-D0185). 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .

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