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Isoforms Recommended:	TNFRSF6/Fas/CD95

Results for "

FAS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	17β-HSD (1) Amino Acid Derivatives (1) AMPK (1) Antibiotic (1) Apoptosis (28) Bacterial (2) Bcl-2 Family (3) c-Myc (1) C-type Lectin-like Receptors (CTLRs) (1) Calcium Channel (1) Caspase (6) Cholinesterase (ChE) (2) Drug Intermediate (2) Endogenous Metabolite (2) FAP (1) Fatty Acid Synthase (FASN) (14) Fungal (3) GLUT (2) Histone Methyltransferase (1) iGluR (1) Indoleamine 2,3-Dioxygenase (IDO) (1) MDM-2/p53 (1) MicroRNA (2) Mitochondrial Metabolism (1) mRNA (2) PARP (1) PKC (2) PPAR (2) PTEN (2) Reactive Oxygen Species (ROS) (1) Reference Standards (6) REV-ERB (1) RIP kinase (1) SARS-CoV (2) Sirtuin (1) Small Interfering RNA (siRNA) (5) STAT (2) TNF Receptor (5) Topoisomerase (2) TRP Channel (1)
By Research Areas:	Cancer (30) Cardiovascular Disease (4) Infection (8) Inflammation/Immunology (14) Metabolic Disease (13) Neurological Disease (5)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (2) mRNA (2) Human Pre-designed siRNA Sets (2) siRNAs (5)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101849

Fasentin 4 Publications Verification	GLUT TNF Receptor Apoptosis	Cardiovascular Disease Cancer
Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC₅₀=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .

HY-103323

Fas C-Terminal Tripeptide	FAP	Others
Fas C-Terminal Tripeptide is a C-terminal tripeptide of Fas. Fas C-Terminal Tripeptide shows the inhibitory effect on *Fas/FAP-1* binding .

HY-P5797

Fasciculin-II FAS-2	Cholinesterase (ChE)	Neurological Disease
Fasciculin-II (Fas-2) is a potential inhibitor of acetylcholinesterase (AChE) .

HY-RS23147

Fas Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fas Rat Pre-designed siRNA Set A contains three designed siRNAs for Fas gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fas Rat Pre-designed siRNA Set A Fas Rat Pre-designed siRNA Set A

HY-RS16712

Fas Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fas Mouse Pre-designed siRNA Set A Fas Mouse Pre-designed siRNA Set A

HY-RS04751

FAS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FAS Human Pre-designed siRNA Set A contains three designed siRNAs for FAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FAS Human Pre-designed siRNA Set A FAS Human Pre-designed siRNA Set A

HY-101849R

Fasentin (Standard)	Reference Standards GLUT TNF Receptor Apoptosis	Cardiovascular Disease Cancer
Fasentin (Standard) is the analytical standard of Fasentin. This product is intended for research and analytical applications. Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .

HY-P5798

Fasciculin-I FAS-I	Cholinesterase (ChE)	Neurological Disease
Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .

HY-RS04754

Fasn Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Fatty Acid Synthase (FASN)	Others
Fasn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fasn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fasn Mouse Pre-designed siRNA Set A Fasn Mouse Pre-designed siRNA Set A

HY-RS04753

FASN Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Fatty Acid Synthase (FASN)	Others
FASN Human Pre-designed siRNA Set A contains three designed siRNAs for FASN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FASN Human Pre-designed siRNA Set A FASN Human Pre-designed siRNA Set A

HY-P99133

*Anti-Mouse Fas* Ligand Antibody (MFL3)**	TNF Receptor	Inflammation/Immunology Cancer
Anti-Mouse Fas Ligand Antibody (MFL3) is an anti-mouse Fas Ligand IgG antibody inhibitor derived from host Armenian Hamster. Anti-Mouse Fas Ligand Antibody (MFL3) can block Fas Ligand (FasL). Anti-Mouse Fas Ligand Antibody (MFL3) can be used for the researches of cancer and immunology .

HY-174714

*Human FAS* mRNA**	mRNA	Inflammation/Immunology
Human FAS mRNA encodes the human Fas cell surface death receptor (FAS) protein, a member of the TNF-receptor superfamily. FAS has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.

HY-P10102

Kp7-6 2 Publications Verification	Apoptosis	Metabolic Disease Cancer
Kp7-6, a Fas mimetic peptide, is a *Fas/FasL* antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury .

HY-16100

BI 99179 1 Publications Verification	Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
BI 99179, a chemical probe, is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC₅₀ of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats .

HY-150190

F5446	Histone Methyltransferase Apoptosis	Cancer
F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo .

HY-103347

M50054	Apoptosis	Inflammation/Immunology
M50054 is a potent inhibitor of apoptosis. M50054 inhibits Etoposide-induced caspase-3 activation of U937 cells with an IC₅₀ of 79 μg/mL. M50054 does not directly inhibit the enzymatic activity of caspase-3. M50054 can be used for the research anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia .

HY-129624A

Bisindolylmaleimide VIII acetate 1 Publications Verification Ro 31-7549 acetate; Bis VIII acetate	PKC Apoptosis	Inflammation/Immunology Cancer
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC₅₀ of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC₅₀s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-β_I, PKC-β_II, PKC-γ, PKC-ε, respectively . Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases .

HY-129624

Bisindolylmaleimide VIII Ro 31-7549; Bis VIII	PKC Apoptosis	Inflammation/Immunology Cancer
Bisindolylmaleimide VIII (Ro 31-7549) is a potent and selective protein kinase C (PKC) inhibitor with an IC₅₀ of 158 nM for rat brain PKC. Bisindolylmaleimide VIII has IC₅₀s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-β_I, PKC-β_II, PKC-γ, PKC-ε, respectively . Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases .

HY-103347R

M50054 (Standard)	Reference Standards Apoptosis	Inflammation/Immunology
M50054 (Standard) is the analytical standard of M50054. This product is intended for research and analytical applications. M50054 is a potent inhibitor of apoptosis. M50054 inhibits Etoposide-induced caspase-3 activation of U937 cells with an IC50 of 79 μg/mL. M50054 does not directly inhibit the enzymatic activity of caspase-3. M50054 can be used for the research anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia .

HY-118147

ML356	Fatty Acid Synthase (FASN)	Cancer
ML356 (Compound 16) is an inhibitor for fatty acid synthase (FAS), that inhibits the thioesterase domain of FAS (FAS TE) with an IC₅₀ of 0.334 μM, and blocks the de novo palmitate synthesis in PC-3 cell with an IC₅₀ of 20 μM. ML356 exhibits good membrane permeability, and good stability in human and mouse plasma .

HY-P10227

Xelafaslatide ONL-1204	Fatty Acid Synthase (FASN)	Metabolic Disease
Xelafaslatide is a *Fatty acid synthase (Fas) receptor* antagonist.

HY-174713

Human FASLG mRNA	mRNA	Inflammation/Immunology
Human FASLG mRNA encodes the human Fas ligand (FASLG) protein, a member of the tumor necrosis factor superfamily. The primary function of the FASLG is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers.

HY-P6440

Met-12	Apoptosis Caspase	Others
Met-12 is a small peptide inhibitor of the Fas receptor. Met-12 can inhibit Fas receptor-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor .

HY-100755

KR-33493	TNF Receptor	Neurological Disease
KR-33493 is a potent inhibitor of Fas-mediated cell death (FAF1).

HY-112716

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 1 Publications Verification	Amino Acid Derivatives	Cancer
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.

HY-108610A

Edelfosine ET-18-OCH3	Apoptosis	Cancer
Edelfosine (ET-18-OCH3) is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor .

HY-103348

Boc-Asp(OMe)-fluoromethyl ketone Boc-Asp(OMe)-FMK	Caspase	Inflammation/Immunology
Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8 .

HY-146197

Apoptotic agent-1	Apoptosis	Cancer
Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes .

HY-N6777

Penicillic acid 1 Publications Verification	Caspase Bacterial Apoptosis Antibiotic	Infection Cancer
Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 .

HY-103243

TCPOBOP 3 Publications Verification	Bcl-2 Family	Cancer
TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss . TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins .

HY-167879A

NPD6433	Fungal Fatty Acid Synthase (FASN)	Infection Inflammation/Immunology
NPD6433 is a triazenyl indole with broad-spectrum activity against all screening fungal strains. NPD6433 targets the enoyl reductase domain of fatty acid synthase 1 (Fas1), covalently inhibiting its flavin mononucleotide-dependent NADPH-oxidation activity and arresting essential fatty acid biosynthesis .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

HY-12325

GSK2194069 4 Publications Verification	Fatty Acid Synthase (FASN)	Cancer
GSK2194069 is a potent inhibitor of β-ketoyl reductase (KR) of fatty acid synthase (FASN), with an IC₅₀ value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on *FAS* expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC₅₀ or K_i values of 4.8 nM and 5.6 nM, respectively .

HY-N7930

Crenulatin	Others	Others
Crenulatin is a gallotannin that can be isolated from Rhodiola rosea. Crenulatin can be used as a biomarker to identify potentially adulterated R. rosea products. Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, via regulating Fas/Bcl-2 expression and caspase-3 activity .

HY-103243R

TCPOBOP (Standard)	Reference Standards Bcl-2 Family	Cancer
TCPOBOP (Standard) is the analytical standard of TCPOBOP. This product is intended for research and analytical applications. TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss . TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins .

HY-167879

(Rac)-NPD6433	Fungal Fatty Acid Synthase (FASN)	Infection Inflammation/Immunology
(Rac)-NPD6433 is a racemate of NPD6433. NPD6433 is a triazenyl indole with broad-spectrum activity against all screening fungal strains. NPD6433 targets the enoyl reductase domain of fatty acid synthase 1 (Fas1), covalently inhibiting its flavin mononucleotide-dependent NADPH-oxidation activity and arresting essential fatty acid biosynthesis .

HY-133897

(Rac)-Indoximod 1 Publications Verification 1-Methyl-DL-tryptophan; (Rac)-NLG-8189	Indoleamine 2,3-Dioxygenase (IDO) Apoptosis	Inflammation/Immunology Cancer
(Rac)-Indoximod (1-Methyl-DL-tryptophan) is an indoleamine 2,3-dioxygenase (IDO) inhibitor. Co-treatment with IFN-γ and (Rac)-Indoximod markedly reduces the activity of human cardiac myofibroblasts (hCMs) expressing α-SMA and induces apoptosis through up-regulating the IRF-1, Fas, and FasL genes .

HY-Y0598

trans-Chalcone	Fatty Acid Synthase (FASN) Apoptosis Fungal	Inflammation/Immunology Cancer
trans-Chalcone, isolated from Aronia melanocarpa skin, is a biphenolic core structure of flavonoids precursor. trans-Chalcone is a potent fatty acid synthase (FAS) and α-amylase inhibitor. trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7. trans-Chalcone has antifungal and anticancer activity .

HY-21088

3-Amino-2-piperidinone Cyclo-ornithine	Endogenous Metabolite Drug Intermediate	Metabolic Disease
3-amino-2-piperidinone is a cyclic ornithine analogue. 3-amino-2-piperidinone can be used to synthesize N-(2-oxopiperidin-3-yl)dodecanamide. N-(2-oxopiperidin-3-yl)dodecanamide inhibits Fas-induced Apoptosis .

HY-P3779

Amyloid 17-42 Aβ(17-42)	Apoptosis	Neurological Disease
Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP). Amyloid 17-42 can induce neuronal apoptosis via a Fas-like/caspase-8 activation pathway .

HY-P991606

TRX585	C-type Lectin-like Receptors (CTLRs)	Infection Inflammation/Immunology Cancer
TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research .

HY-P10815

IP3RCYT	Apoptosis Calcium Channel	Others
IP3RCYT is an IP₃R inhibitory peptide, which can inhibit the binding of cytochrome C to IP₃R with an IC₅₀ about 100 nM. IP3RCYT regulates calcium signaling within cells. P3RCYT inhibits apoptosis in HeLa and Jurkat cells treated with Staurosporine (HY-15141) or Membrane-bound Fas ligand (FasL) .

HY-13721

Phenoxodiol 3 Publications Verification Idronoxil; Dehydroequol; Haginin E	Caspase Apoptosis Topoisomerase	Cancer
Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21 ^WAF1 via a p53 independent manner .

HY-168877

FMP	MDM-2/p53 Reactive Oxygen Species (ROS) Apoptosis Caspase PARP Bcl-2 Family	Cancer
FMP is a Platinum(IV) complexe. FMP significantly upregulates the expression of γ-H2AX and p53. FMP increases the production of ROS. FMP markedly upregulates the expressions of Apoptosis-related proteins (*DR5, Fas, caspase-8, Cyt-c, caspase-3, cleaved-PARP1, Bax*). FMP shows antiproliferative activity against breast cancer .

HY-P10401

TAT-GluR6-9c	Apoptosis iGluR	Cardiovascular Disease Neurological Disease
TAT-GluR6-9c is a GluR6-PSD95 interaction blocker. By regulating the GluR6 mediated signaling pathway, TAT-GluR6-9c inhibits the activation of JNK and phosphorylation of c-Jun, reduces the expression of Fas L and thus reduces the occurrence of apoptosis. TAT-GluR6-9c can be used to study cerebral ischemia and neuroprotective strategies .

HY-13721R

Phenoxodiol (Standard)	Caspase Apoptosis Topoisomerase	Cancer
Phenoxodiol (Standard) is the analytical standard of Phenoxodiol. This product is intended for research and analytical applications. Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner .

HY-21088R

3-Amino-2-piperidinone (Standard)	Endogenous Metabolite Drug Intermediate	Metabolic Disease
3-Amino-2-piperidinone (Standard) is the analytical standard of 3-Amino-2-piperidinone. This product is intended for research and analytical applications. 3-amino-2-piperidinone is a cyclic ornithine analogue. 3-amino-2-piperidinone can be used to synthesize N-(2-oxopiperidin-3-yl)dodecanamide. N-(2-oxopiperidin-3-yl)dodecanamide inhibits Fas-induced Apoptosis .

HY-168770

Cl-Necrostatin-1	RIP kinase TNF Receptor Apoptosis	Cardiovascular Disease
Cl-Necrostatin-1 is a RIPK1 inhibitor. Cl-Necrostatin-1 can also inhibit TNF-α-induced necroptosis in Jurkat cells deficient in Fas-associated death domain protein (FADD; EC₅₀ = 180 nM), a modification that prevents caspase activation in response to death-domain receptor signaling. Cl-Necrostatin-1 can also reduce infarct size in a mouse model of middle cerebral artery occlusion (MCAO). Cl-Necrostatin-1 is used for research in cardiovascular and cerebrovascular diseases .

HY-B0515B

Ibandronate Sodium	Apoptosis	Metabolic Disease Cancer
Ibandronate Sodium is an orally active, selective inhibitor of farnesyl pyrophosphate synthase (FPP synthase). Ibandronate Sodium can block the mevalonate pathway to inhibit the isoprenylation modification of small GTPases (such as RAS, RHO family proteins), induce tumor cell apoptosis and inhibit bone resorption. Ibandronate Sodium inhibits tumor cell proliferation (such as ER+ breast cancer cells), promotes the expression of the pro-apoptotic gene FAS, and can produce synergistic anti-tumor effects with anti-estrogen compounds. Ibandronate Sodium is used in the study of osteoporosis and bone metastatic tumors (such as breast cancer bone metastasis) .

HY-N2116

Ginkgolic acid C17:1	PTEN Fatty Acid Synthase (FASN) STAT Apoptosis SARS-CoV	Infection Cancer
Ginkgolic acid C17:1 is a fatty acid synthase (FAS) inhibitor with an IC₅₀ of 10.5 µM. Ginkgolic acid C17:1 shows anti-tumor activity by inhibiting the phosphorylation of STAT3 and inducing apoptosis. Ginkgolic acid C17:1 can block the interaction between S-RBD and ACE2, and has anti-SARS-CoV-2-S pseudovirus activity. Ginkgolic acid C17:1 inhibits the biofilm formation of enterohemorrhagic Escherichia coli and Staphylococcus aureus .

Cat. No.	Product Name

HY-L182

Fatty Acids Compound Library

287 compounds

Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases.

MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Cat. No.	Product Name	Target	Research Area

HY-P10102

Kp7-6 2 Publications Verification	Apoptosis	Metabolic Disease Cancer
Kp7-6, a Fas mimetic peptide, is a *Fas/FasL* antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury .

HY-P10227

Xelafaslatide ONL-1204	Fatty Acid Synthase (FASN)	Metabolic Disease
Xelafaslatide is a *Fatty acid synthase (Fas) receptor* antagonist.

HY-P6440

Met-12	Apoptosis Caspase	Others
Met-12 is a small peptide inhibitor of the Fas receptor. Met-12 can inhibit Fas receptor-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor .

HY-P1743

Acyl Carrier Protein (ACP) (65-74)	Peptides	Infection
Acyl Carrier Protein (ACP) (65-74) is a key coenzyme fragment of fatty acid synthase (FAS) and participates in fatty acid synthesis as an acyl carrier. Acyl Carrier Protein (ACP) (65-74) mediates condensation, reduction and other cyclic reactions in fatty acid synthesis by covalently binding to acyl chains to form acyl-ACP intermediates, promoting acyl chain extension. Acyl Carrier Protein (ACP) (65-74) can regulate the synthesis ratio of saturated and unsaturated fatty acids. Acyl Carrier Protein (ACP) (65-74) can be used to study the mechanism of bacterial fatty acid synthesis and is a potential target for antibiotics (such as inhibiting the FAS system of pathogens) .

HY-P5797

Fasciculin-II FAS-2	Cholinesterase (ChE)	Neurological Disease
Fasciculin-II (Fas-2) is a potential inhibitor of acetylcholinesterase (AChE) .

HY-P5798

Fasciculin-I FAS-I	Cholinesterase (ChE)	Neurological Disease
Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

HY-P3779

Amyloid 17-42 Aβ(17-42)	Apoptosis	Neurological Disease
Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP). Amyloid 17-42 can induce neuronal apoptosis via a Fas-like/caspase-8 activation pathway .

HY-P10815

IP3RCYT	Apoptosis Calcium Channel	Others
IP3RCYT is an IP₃R inhibitory peptide, which can inhibit the binding of cytochrome C to IP₃R with an IC₅₀ about 100 nM. IP3RCYT regulates calcium signaling within cells. P3RCYT inhibits apoptosis in HeLa and Jurkat cells treated with Staurosporine (HY-15141) or Membrane-bound Fas ligand (FasL) .

HY-P10401

TAT-GluR6-9c	Apoptosis iGluR	Cardiovascular Disease Neurological Disease
TAT-GluR6-9c is a GluR6-PSD95 interaction blocker. By regulating the GluR6 mediated signaling pathway, TAT-GluR6-9c inhibits the activation of JNK and phosphorylation of c-Jun, reduces the expression of Fas L and thus reduces the occurrence of apoptosis. TAT-GluR6-9c can be used to study cerebral ischemia and neuroprotective strategies .

Cat. No.	Product Name	Target	Research Area

HY-P99133

*Anti-Mouse Fas* Ligand Antibody (MFL3)**	TNF Receptor	Inflammation/Immunology Cancer
Anti-Mouse Fas Ligand Antibody (MFL3) is an anti-mouse Fas Ligand IgG antibody inhibitor derived from host Armenian Hamster. Anti-Mouse Fas Ligand Antibody (MFL3) can block Fas Ligand (FasL). Anti-Mouse Fas Ligand Antibody (MFL3) can be used for the researches of cancer and immunology .

HY-P991606

TRX585	C-type Lectin-like Receptors (CTLRs)	Infection Inflammation/Immunology Cancer
TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research .

Species:	Human (14) Mouse (5) Rat (2) Cynomolgus (3)
Tag:	His (15) Tag Free (3) Avi (2) GST (1) Fc (5)
Source:	HEK293 (15) P. pastoris (3) Sf9 insect cells (1) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P70330

	Fas/CD95 Protein, Mouse (HEK293, His) rMuTumor necrosis factor receptor superfamily member 6//TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD95; FAS; TNFRSF6	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, His) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P7169

	Fas/CD95 Protein, Human rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; FAS receptor; CD95; APT1; FAS1; Apo-1	Human	E. coli
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human has a full length of 157 amino acids (R17-N173), produced in E.coli with tag free.

HY-P7168

	Fas/CD95 Protein, Human (HEK293) rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; FAS receptor; CD95; APT1; FAS1; Apo-1	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.

HY-P78296

	Fas/CD95 Protein, Mouse (HEK293, Fc) FASLG receptor; CD95; APT1; FAS1; TNFRSF6; FAS; ALPS1A; APO1; FASTM; FASR	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, Fc) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal hFc-tag.

HY-P76330

	Fas/CD95 Protein, Cynomolgus (HEK293) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6	Cynomolgus	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293) has a full length of 173 amino acids (M1-D173), produced in HEK293 cells with tag free.

HY-P73049

	Fas/CD95 Protein, Rat (HEK293, His) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6	Rat	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Rat Fas receptor contain a death domain (219-303 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Rat (HEK293, His) has a full length of 149 amino acids (Q22-K170), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P703920

	Fas/CD95 Protein, Cynomolgus (HEK293, hFc) FAS cell surface death receptor	Cynomolgus	HEK293
	Fas/CD95 Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived Fas/CD95 protein, expressed by HEK293, with C-hFc tag.

HY-P73047

	Fas/CD95 Protein, Human (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, Fc) has a full length of 173 amino acids (M1-N173), produced in HEK293 cells with C-terminal hFc-tag.

HY-P73048

	Fas/CD95 Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6	Rat	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Rat Fas receptor contain a death domain (219-303 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Rat (HEK293, Fc) produced in HEK293 cells with C-terminal hFc tag.

HY-P76331

	Fas/CD95 Protein, Cynomolgus (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6	Cynomolgus	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293, Fc) is produced in HEK293 cells with C-terminal hFc-tag.

HY-P70329

	Fas/CD95 Protein, Human (HEK293, His) rHuTumor necrosis factor receptor superfamily member 6/TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; APT1; FAS1; TNFRSF6 and FAS	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, His) has a full length of 147 amino acids (Q26-N173), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P700520

	Fas Ligand Protein, Human (His) Apoptosis antigen ligand ; APTLCD95 ligand ; CD95-LFAS antigen ligand ; FAS ligand ; FASL; CD178	Human	E. coli
	FASLG protein binds to TNFRSF6/FAS and triggers apoptotic signals.Fas Ligand Protein, Human (His) is the recombinant human-derived FASLG protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700521

	Fas Ligand Protein, Human (P.pastoris, His) Apoptosis antigen ligand ; APTLCD95 ligand ; CD95-LFAS antigen ligand ; FAS ligand ; FASL; CD178	Human	P. pastoris
	FASLG protein binds to TNFRSF6/FAS and triggers apoptotic signals. Fas Ligand Protein, Human (P.pastoris, His) is the recombinant human-derived FASLG protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P72658

	Fas Ligand Protein, Human (HEK293, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; FAS ligand; FASL; CD178; TNFSF6	Human	HEK293
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (HEK293, His) has a total length of 148 amino acids (P134-L281), is expressed in HEK392 cells with N-terminal 6*His-tag.

HY-P74157

	Fas Ligand Protein, Mouse (P.pastoris, His) 1 Publications Verification Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; FAS ligand; FASL; CD178; TNFSF6	Mouse	P. pastoris
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Mouse Fas Ligand has a total length of 279 amino acids (M1-L279), with a TNF_2 domain (144-279 a.a.). Fas Ligand Protein, Mouse (P.pastoris, His) is a recombinant protein expressed in P.pastoris cells with N-terminal His-tag.

HY-P72658A

	Fas Ligand Protein, Human (HEK293, N-His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; FAS ligand; FASL; CD178; TNFSF6	Human	HEK293
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (HEK293, His) has a total length of 148 amino acids (P134-L281), is expressed in HEK392 cells with N-terminal 6*His-tag.

HY-P74158

	Fas Ligand Protein, Human (148a.a, P.pastoris, His) Tumor necrosis factor ligand superfamily member 6; APTL; CD95-L; FAS ligand; FASL; CD178; TNFSF6	Human	P. pastoris
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Fas Ligand Protein, Human (148a.a, P.pastoris, His) has a total length of 148 amino acids (P134-L281), with a TNF_2 domain (146-281 a.a.). It is a recombinant protein expressed in P.pastoris cells with N-terminal His-tag.

HY-P700176AF

	*Animal-Free Fas* Ligand Protein, Mouse (His)** 1 Publications Verification soluble FAS Ligand (sFASL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178; FAS-Lg; Tnfs; Tnlg1a; gld	Mouse	E. coli
	The cytoplasmic form of Fas ligand protein exerts powerful effects by inhibiting gene transcription. This protein plays a crucial role in regulating cellular processes by inhibiting the expression of specific genes. Animal-Free Fas Ligand Protein, Mouse (His) is the recombinant mouse-derived animal-FreeFas Ligand protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P700052AF

	*Animal-Free Fas* Ligand Protein, Human (His)** 1 Publications Verification soluble FAS Ligand (sFASL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178	Human	E. coli
	Fas Ligand (CD178; APTL) is a ligand to TNFRSF6/FAS/CD95, transduces the apoptotic signal to regulate cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Human Fas Ligand exhibits 4 isoforms, the soluble form (130-281 a.a.) of which plays an important role in the activation-induced cell death (AICD) of T lymphocytes Jurkat cells. However the membrane-bound isoform could be responsible for its inflammatory activity. Animal-Free Fas Ligand Protein, Human (His) has a total length of 152 amino acids (Q130-L281), is expressed in E. coli with N-terminal His-tag.This product is for cell culture use only.

HY-P701698

	HIPK3 Protein, Human (sf9, GST) HIPK3; Homeodomain-interacting protein kinase 3; Androgen receptor-interacting nuclear protein kinase; ANPK; FAS-interacting serine/threonine-protein kinase; FIST; Homolog of protein kinase YAK1	Human	Sf9 insect cells
	HIPK3 is a multifaceted serine/threonine protein kinase that plays multiple roles in transcriptional regulation, apoptosis, and steroidogenic gene expression. It phosphorylates the transcription factors JUN and RUNX2, contributing to complex gene expression control. HIPK3 Protein, Human (sf9, GST) is the recombinant human-derived HIPK3 protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P78363

	TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) CD262; DR5; DR5TRICK2B; FAS-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER	Mouse	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and activates apoptosis through FADD-mediated recruitment of caspase-8 to form death-inducing signaling complex (DISC).It initiates caspase cascade-mediated apoptosis and promotes NF-kappa-B activation, which is critical for ER stress-induced apoptosis.TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) is the recombinant mouse-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-His labeled tag.

HY-P78530

	TRAIL R2/TNFRSF10B Protein, Human (HEK293, His-Avi) CD262; DR5; DR5TRICK2B; FAS-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER	Human	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and recruits caspase-8 through FADD to initiate cell apoptosis. It forms the death-inducing signaling complex (DISC), activates caspases and mediates apoptosis. TRAIL R2/TNFRSF10B Protein, Human (HEK293, His-Avi) is the recombinant human-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78220

	TRAIL R2/TNFRSF10B Protein, Human (Biotinylated, HEK293, His-Avi) CD262; DR5; DR5TRICK2B; FAS-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER	Human	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and recruits caspase-8 through FADD to initiate cell apoptosis. It forms the death-inducing signaling complex (DISC), activates caspases and mediates apoptosis. TRAIL R2/TNFRSF10B Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P79135

	Stabilin-2 Protein, Human (His) Stabilin-2; STAB2; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; FASciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2; Hyaluronan receptor for endocytosis; FEEL2; FELL; FEX2; HARE	Human	E. coli
	Stabilin-2 protein is a multifunctional phosphatidylserine and hyaluronic acid receptor that engulfs apoptotic cells and mediates hyaluronic acid endocytosis. As a systemic scavenger receptor, it binds various ligands and supports extracellular matrix turnover and body mobility. Stabilin-2 Protein, Human (His) is the recombinant human-derived Stabilin-2 protein, expressed by E. coli , with C-His labeled tag.

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HY-P80666

	Fas Antibody (YA447) FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6	WB, IHC-F, IHC-P, ICC/IF	Human
	Fas Antibody (YA447) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P80668

	Fatty Acid Synthase Antibody (YA766) FASN; FAS; Fatty acid synthase	WB, ICC/IF, IP	Human, Mouse, Rat, Monkey
	Fatty Acid Synthase Antibody (YA766) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Fatty Acid Synthase.

HY-P86362

	Fatty Acid Synthase Antibody (YA6054) FASN; FAS; Fatty acid synthase	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Fatty Acid Synthase Antibody (YA6054) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fatty Acid Synthase.

HY-P83109

	Daxx Antibody (YA2854) DAXX; BING2; DAP6; Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; EAP1; FAS death domain-associated protein	WB, ICC/IF	Human
	Daxx Antibody (YA2854) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Daxx.

HY-P80126

	Fas Antibody (YA446)	WB, IHC-P, ICC/IF	Human
	Fas Antibody (YA446) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P86549

	Fas Antibody (YA6241) FAS; APT1; FAS1; TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD antigen CD95	WB, IHC-P, ICC/IF, IP, ELISA	Human
	Fas Antibody (YA6241) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P85515

	Fas(C-term) Antibody (YA5207) ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen FAS; Apoptosis-mediating surface antigen FAS; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta FAS; Delta FAS/APO 1/CD95; Delta FAS/APO1/CD95; FAS; TNF receptor superfamily, member 6; FAS 1; FAS 827dupA; FAS AMA; FAS; FAS Antigen; FAS cell surface death receptor; FAS1; FASLG receptor; FASTM; sFAS; Surface antigen APO1; TNF receptor superfamily, member 6; TNFRSF 6; TNFRSF6; TNR6_HUMAN; Tumor necrosis factor receptor superfamily member 6.	WB	Human
	Fas(C-term) Antibody (YA5207) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fas(C-term).

HY-P84345

	Fas Ligand Antibody (YA4042) FASLG; APTL; FASL; CD95L; ALPS1B; CD95-L; TNFSF6; TNLG1A; APT1LG1	ICC/IF, FC, ELISA	Human
	Fas Ligand Antibody (YA4042) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fas Ligand.

HY-P85636

	FADD Antibody (YA5328) FADD; FADD protein; FADD_HUMAN; FAS; TNFRSF6; associated via death domain; FAS associated via death domain; FAS associating death domain containing protein; FAS associating death domain containing protein; FAS associating protein; FAS associating protein with death domain; FAS associating protein with death domain; FAS TNFRSF6 associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; FASTNFRSF6 associated via death domain; FASTNFRSF6 associated via death domain; GIG 3; GIG3; Growth inhibiting gene 3 protein; Growth-inhibiting gene 3 protein; H sapiens mRNA for mediator of receptor induced toxicity; H sapiens mRNA for mediator of receptor induced toxicity; Mediator of receptor induced toxicity; Mediator of receptor induced toxicity; MGC8528; MGC8528; MORT 1; MORT1; MORT1; Protein FADD.	WB	Human
	FADD Antibody (YA5328) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FADD.

HY-P85118

	Daxx Antibody (YA4810) DAXX; BING2; DAP6; Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; EAP1; FAS death domain-associated protein	WB, ICC/IF, FC, ELISA	Human
	Daxx Antibody (YA4810) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Daxx.

HY-P82621

	Caspase-10 Antibody (YA2366) CASP10; MCH4; Caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4	WB, IHC-P, IP	Human
	Caspase-10 Antibody (YA2366) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-10.

HY-P80916

	DR5 Antibody (YA660) FAS like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; D	WB, ICC/IF	Human, Mouse
	DR5 Antibody (YA660) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DR5.

HY-P85577

	DR5 Antibody (YA5269) FAS like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; DR5; FAS like protein precursor; KILLER; KILLER/DR5; OTTHUMP00000123492; OTTHUMP00000123493; p53 regulated DNA damage inducible cell death receptor; killer; p53 regulated DNA damage inducible cell death receptor; killer; TNF related apoptosis inducing ligand receptor 2; TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TR10B_HUMAN; TRAIL R2; TRAIL receptor 2; TRAIL-R2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10b; Tumor necrosis factor receptor superfamily, member 10b; ZTNFR9.	WB, ICC	Human, Mouse
	DR5 Antibody (YA5269) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to DR5.