FADD Antibody (YA5328)

FADD Antibody (YA5328) is a mouse-derived and non-conjugated monoclonal antibody, targeting to FADD. It can be applicated for WB assays, in the background of human.

FADD is an apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting complex, called the death-inducing signaling complex (DISC), performs proteolytic activation of CASP8. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Additionally, FADD is involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. by similar content includes: FADD's function in DISC and its role in the apoptotic cascade.

Q13158

Observed band size: 23 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:1000

WB

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant human FADD protein fragments expressed in E.coli.