2. Apoptosis
  3. Apoptosis Caspase
  4. Met-12

Met-12 is a small peptide inhibitor of the Fas receptor. Met-12 can inhibit Fas receptor-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Met-12 Chemical Structure

Met-12 Chemical Structure

CAS No. : 1242964-46-0

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Met-12 Related Antibodies

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Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

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Description

Met-12 is a small peptide inhibitor of the Fas receptor. Met-12 can inhibit Fas receptor-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor[1].

Molecular Weight

1462.65

Formula

C71H99N17O17
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (68.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6837 mL 3.4185 mL 6.8369 mL
5 mM 0.1367 mL 0.6837 mL 1.3674 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6837 mL 3.4185 mL 6.8369 mL 17.0923 mL
5 mM 0.1367 mL 0.6837 mL 1.3674 mL 3.4185 mL
10 mM 0.0684 mL 0.3418 mL 0.6837 mL 1.7092 mL
15 mM 0.0456 mL 0.2279 mL 0.4558 mL 1.1395 mL
20 mM 0.0342 mL 0.1709 mL 0.3418 mL 0.8546 mL
25 mM 0.0273 mL 0.1367 mL 0.2735 mL 0.6837 mL
30 mM 0.0228 mL 0.1139 mL 0.2279 mL 0.5697 mL
40 mM 0.0171 mL 0.0855 mL 0.1709 mL 0.4273 mL
50 mM 0.0137 mL 0.0684 mL 0.1367 mL 0.3418 mL
60 mM 0.0114 mL 0.0570 mL 0.1139 mL 0.2849 mL
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Met-12 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Met-121242964-46-0Met12Met 12ApoptosisCaspase661W cellsInhibitorinhibitorinhibit

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