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Results for "

helix-loop-helix

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

4

Recombinant Proteins

48

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-129241
    AGX51
    5+ Cited Publications

    DNA/RNA Synthesis DNA Alkylator/Crosslinker Cancer
    AGX51 is the first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and viability reduction. AGX51 can inhibit TNBC and has an IC50 of about 25 nM. AGX51 can be used in cancer research.
    AGX51
  • HY-174570

    mRNA Neurological Disease
    Human NEUROG3 mRNA encodes the human neurogenin 3 (NEUROG3) protein, a basic helix-loop-helix (bHLH) transcription factor that involved in neurogenesis.
    Human NEUROG3 mRNA
  • HY-174571

    mRNA Neurological Disease
    Human NEUROG2 mRNA encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells. NEUROG2 plays a role in the differentiation and survival of midbrain dopaminergic neurons.
    Human NEUROG2 mRNA
  • HY-174778

    mRNA Neurological Disease
    Human ASCL1 mRNA encodes the human achaete-scute family bHLH transcription factor 1 (ASCL1) protein, a member of the basic helix-loop-helix (BHLH) family. ASCL1 plays a role in the neuronal commitment and differentiation, and in the generation of olfactory and autonomic neurons.
    Human ASCL1 mRNA
  • HY-174580

    mRNA Cancer
    Human MITF mRNA encodes the human melanocyte inducing transcription factor (MITF) protein, a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. MITF could regulate melanocyte development and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes.
    Human MITF mRNA
  • HY-174573

    mRNA Neurological Disease
    Human NEUROD1 mRNA encodes the human neuronal differentiation 1 (NEUROD1)protein, a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. NEUROD1 forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box.
    Human NEUROD1 mRNA
  • HY-174575

    mRNA Cancer
    Human MYOD1 mRNA encodes the human myogenic differentiation 1 (MYOD1) protein, a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. MYOD1 acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
    Human MYOD1 mRNA
  • HY-174572

    mRNA Neurological Disease
    Human NEUROD2 mRNA encodes the human neuronal differentiation 2 (NEUROD2) protein, a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Human NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
    Human NEUROD2 mRNA
  • HY-174536

    mRNA Cancer
    Human TFE3 mRNA encodes the human transcription factor binding to IGHM enhancer 3 (TFE3) protein, a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences. TFE3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins.
    Human TFE3 mRNA

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