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Results for "

Resistant bacteria

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Antibiotic (84) Apoptosis (1) Arginase (2) Bacterial (183) Beta-lactamase (5) Calcium Channel (1) Cytochrome P450 (1) DNA/RNA Synthesis (3) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (1) Fungal (6) HIV (1) Isotope-Labeled Compounds (2) Monoamine Oxidase (2) Nucleoside Antimetabolite/Analog (1) Parasite (3) Protein Arginine Deiminase (1) Reactive Oxygen Species (ROS) (3) Reference Standards (13) SARS-CoV (1) Toll-like Receptor (TLR) (1) Topoisomerase (5)
By Research Areas:	Cancer (31) Cardiovascular Disease (1) Infection (186) Inflammation/Immunology (10) Neurological Disease (1)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Nucleosides and their Analogs (1) C (1) Solubilizing Agents (1) Freeze-drying Protective Agents (1)

199

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0279

Pristinamycin Pristinamycine	Bacterial Antibiotic	Infection
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

HY-146595

FtsZ-IN-1	Bacterial	Infection
FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity .

HY-N14653

Glysperin A	Bacterial	Infection
Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-B1075A

Fosfomycin MK-0955	Bacterial Antibiotic	Infection Cancer
Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-N14654

Glysperin B	Bacterial	Infection
Glysperin B has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-N14680

Glysperin C	Bacterial	Infection
Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-126577

Dactylocycline B	Antibiotic Bacterial
Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria .

HY-N5184

Nocathiacin Ⅲ Nocathiacine III	Bacterial	Infection
Nocathiacin III (Nocathiacine III) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N5195

Nocathiacin II Nocathiacine II	Bacterial	Infection
Nocathiacin II (Nocathiacine II) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N5196

Nocathiacin I Nocathiacine I	Bacterial	Infection
Nocathiacin I (Nocathiacine I) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N14899

Oxasetin	Bacterial	Infection
Oxasetin has medium activity against Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis (MIC is 16 μg/mL). Oxasetin has no activity against Gram-negative bacteria and fungi .

HY-165294

Amidinomycin	Bacterial	Infection
Amidinomycin is mainly resistant to Gram-positive bacteria (weak) .

HY-N14497

Nocardicyclin A	Bacterial	Infection
Nocardicyclin A is resistant to Gram-positive bacteria, mycobacterium and Nocardia .

HY-N13971

Bamicetin	Bacterial	Infection
Bamicetin is mainly resistant to Gram-positive bacteria and Mycobacteria .

HY-N14948

2"-N-Formimidoylsporaricin A	Bacterial	Infection
2"-N-Formimidoylsporaricin A has the activity of anti-Gram-positive bacteria and negative bacteria, and also has the antibacterial activity against the aminoglycol-resistant bacteria .

HY-N14528

Oganomycin A	Bacterial	Infection
Oganomycin A is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-117742

DA-7867	Bacterial	Others
DA-7867 is an antibacterial compound with activity against a wide range of bacteria, including drug-resistant bacteria. DA-7867 shows promising antibacterial activity against some clinically important pathogens, including drug-resistant bacteria. It is an amide analog of Tedizolid, reflecting the potential use of tetrazoles in the development of new antibacterial agents.

HY-N14529

Oganomycin B	Bacterial	Infection
Oganomycin B is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-N13147

Tetromycin C5	Antibiotic Bacterial	Infection
Tetromycin C5 is an antibiotic, that exhibits board-spectrum antibacterial activity against gram-positive bacteria and their drug-resistant bacteria .

HY-106590

Saccharocin Antibiotic KA 5685	Bacterial	Infection
Saccharocin (Antibiotic KA 5685) is effective against Gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria .

HY-B1075AS

(Rac)-Fosfomycin (benzylamine)-13C3 MK-0955 (benzylamine)-¹³C₃	Bacterial Antibiotic	Infection
(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin . Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-N14313

Nocardicyclin B	Bacterial	Infection
Nocardicyclin B is resistant to Gram-positive bacteria, mycobacterium and Nocardia .

HY-W016420

Fosfomycin sodium 5+ Cited Publications MK-0955 sodium	Bacterial Antibiotic	Infection Cancer
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-N14118

Chloropolysporin B	Bacterial	Infection
Chloropolysporin B has strong activity of anti-Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria .

HY-N14119

Chloropolysporin C	Bacterial	Infection
Chloropolysporin C has strong activity of anti-Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria .

HY-B1075

Fosfomycin calcium 5+ Cited Publications MK-0955 calcium	Bacterial Antibiotic	Infection Cancer
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-B0609

Fosfomycin tromethamine 5+ Cited Publications MK-0955 tromethamine	Bacterial Antibiotic	Infection Cancer
Fosfomycin (MK-0955) tromethamine is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin tromethamine shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-W748035

Etamycin A	Antibiotic Bacterial	Infection
Etamycin A is an ester peptide antibiotic. Mainly resistant to Gram-positive bacteria and mycobacteria .

HY-N14706

Kibdelin A	Bacterial	Infection
Kibdelin A is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-W016456

5-Bromopentanoic acid	Drug Intermediate	Others
5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria .

HY-N14489

Neocopiamycin A	Bacterial Fungal	Infection
Neocopiamycin A is broad-spectrum resistant to Gram-positive bacteria, yeast and filamentous fungi .

HY-N14707

Kibdelin B	Bacterial	Infection
Kibdelin B is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14710

Kibdelin D	Bacterial	Infection
Kibdelin D is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14542

Oleficin	Bacterial	Infection Cancer
Oleficin is resistant to Gram-positive bacteria and effective against subcutaneous transplantation of Yoshida sarcoma .

HY-N15059

Cissetin	Bacterial	Infection
Cissetin shows activity against Gram-positive bacteria, including drug-resistant strains .

HY-N14486

Neihumicin	Fungal	Infection
Neihumicin is resistant to beer Saccharomyces yeast ATCC 9763 and Penicillium italium Wehmer, but not to bacteria .

HY-N14709

Kibdelin C2	Bacterial	Infection
Kibdelin C2 is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14708

Kibdelin C1	Bacterial	Infection
Kibdelin C1 is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-14849

PTZ601 Razupenem; SM 216601; SMP 601	Antibiotic Bacterial	Others
PTZ601 (SMP 601) is an antibiotic, which inhibits the gram-positive bacteria, including the Vancomycin (HY-B0671)-resistant Enterococcus faecium (VREF) and Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). PTZ601 exhibits antimicrobial activity in infected mouse models .

HY-N15119

Polymyxin S1	Bacterial	Infection
Polymyxin S1 is found in Bacillus Polymyxa RS-6 and is resistant to Gram-positive bacteria .

HY-N11874

Staphyloferrin A	Bacterial	Infection
Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .

HY-128384

Benzyldodecyldimethylammonium chloride dihydrate	Bacterial	Infection
Benzyldodecyldimethylammonium chloride dihydrate is a quaternary ammonium compound (QAC) and can be used as a biocide to target antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant (MDR) P. aeruginosa et. al. Benzyldodecyldimethylammonium chloride dihydrate, an antimicrobial agent, bacteriostatic or bactericidal properties depending on the concentration.

HY-118036

ACT-387042	Topoisomerase	Infection
ACT-387042 is a bacterial topoisomerase inhibitor with broad-spectrum activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus and penicillin- and fluoroquinolone-resistant Streptococcus pneumoniae .

HY-B1075R

Fosfomycin calcium (Standard) MK-0955 calcium (Standard)	Reference Standards Bacterial Antibiotic	Infection Cancer
Fosfomycin (calcium) (Standard) is the analytical standard of Fosfomycin (calcium). This product is intended for research and analytical applications. Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-167651

TAN-1057C	Bacterial Antibiotic	Infection
TAN-1057C is a potent antibiotic which exhibits antibacterial activity against Gram-negative and Gram-positive bacteria, including Methicillin (HY-121544)-resistant Staphylococcus aureus .

HY-N14125

Chloroquinocin	Bacterial	Infection
Chloroquinocin has moderate activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) .

HY-126629

Antibacterial agent 12	Bacterial	Infection
Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria .

HY-151567

Antibacterial agent 123	Bacterial	Infection
Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria .

HY-116571

RU44790	Antibiotic Bacterial	Infection
RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative *bacteria* and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research .

HY-N15019

Glycothiohexide α	Antibiotic Bacterial	Infection
Glycothiohexide α is a peptide antibiotic. Glycothiohexide α has strong activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VREF), MIC values of 0.03-0.06 μg/mL .

Cat. No.	Product Name

HY-L142

Anti-tuberculosis Compound Library

126 compounds

Tuberculosis (TB), usually caused by bacteria (Mycobacterium tuberculosis), is an infectious disease that mainly affects the lungs. According to the statistics of the World Health Organization (WHO), 10 million people suffer from tuberculosis every year, and 1.5 million people die of tuberculosis every year, which makes tuberculosis the number one killer of infectious diseases.

Tuberculosis can be cured through the standard 6-month course of treatment of four kinds of antibiotics. Common drugs include rifampicin and isoniazid. In some cases, TB bacteria do not respond to standard drugs, that is, patients with drug-resistant tuberculosis. The treatment of drug-resistant tuberculosis takes longer and is more complex. In the face of the resurgence of tuberculosis in the world and the rapid emergence of multi drug resistant tuberculosis, it is very important to develop new anti-tuberculosis drugs or new clinical treatment schemes for existing anti mycobacterium drugs.

MCE supplies a unique collection of 126 compounds with clear anti-tuberculosis activity. MCE Anti-tuberculosis Compound Library is a useful tool for anti-tuberculosis related research and anti-tuberculosis drug development

HY-L049

Antibacterial Compound Library

1,599 compounds

Antibacterial agents are a group of materials that fight against pathogenic bacteria. Thus, by killing or reducing the metabolic activity of bacteria, their pathogenic effect in the biological environments will be minimized. The most widely used antibacterial agents exert their effects on bacterial cell wall synthesis, protein synthesis, DNA replication and metabolic pathways. However, resistance to antimicrobial agents has become a major source of morbidity and mortality worldwide. The main mechanisms of resistance are limiting uptake of a drug, modification of a drug target, inactivation of a drug, and active efflux of a drug. Therefore, it is an urgent need to develop new drugs targeted at resistant organisms.

MCE offers a unique collection of 1,599 compounds with validated antibacterial activities. MCE antibacterial compound library is an effective tool for drug repurposing screening, combination screening and biological investigation.

Cat. No.	Product Name	Type

HY-69174

1-Amino-2,5-anhydro-1-deoxy-D-mannitol

Microbial Culture

1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition.

Cat. No.	Product Name	Target	Research Area

HY-P1649

SPR741 3 Publications Verification NAB741	Bacterial Antibiotic	Infection
SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative *bacteria* and is used to treat severe Gram-negative *bacteria* infections. SPR741 inhibits multidrug-resistant Gram-negative *bacteria*. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 .

HY-P1649B

SPR741 acetate 3 Publications Verification NAB741 acetate	Bacterial Antibiotic	Infection
SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative *bacteria* and is used to treat severe Gram-negative *bacteria* infections. SPR741 acetate inhibits multidrug-resistant Gram-negative *bacteria*. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate .

HY-A0248B

Polymyxin B2	Antibiotic Bacterial	Infection
Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .

HY-P1720

Telomycin	Antibiotic Bacterial	Infection
Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .

HY-P1649A

SPR741 TFA NAB741 TFA	Bacterial Antibiotic	Infection
SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative *bacteria* and is used to treat severe Gram-negative *bacteria* infections. SPR741 TFA inhibits multidrug-resistant Gram-negative *bacteria*. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA .

HY-P5691

P1	Bacterial	Infection Cancer
P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .

HY-P10411

BING	Bacterial	Infection
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .

HY-P10210

Paenilagicin	Antibiotic Bacterial	Infection
Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria .

HY-105048A

Omiganan pentahydrochloride	Bacterial	Infection
Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes .

HY-P10540

Pantinin-2	Bacterial	Infection
Pantinin-2 is a cysteine-free toxic peptide found in the emperor scorpion (paninus imperator). Pantinin-2 has high activity against Gram-positive bacteria but weak activity against Gram-negative bacteria. Pantinin-2 also exhibits activity against Candida tropicalis and has relatively mild hemolytic activity against human erythrocytes. Pantinin-2 can be used in the development of antimicrobial drugs for drug-resistant pathogens .

HY-P3328

MDP1	Bacterial	Infection
MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .

HY-P3328A

MDP1 acetate	Bacterial	Infection
MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .

HY-P10539

Hp1404	Bacterial	Infection
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .

HY-P3349

c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]	Bacterial	Infection
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .

HY-P3348

c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]	Bacterial	Infection
c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .

HY-P0263R

Dermaseptin (Standard)	Reference Standards Bacterial Fungal Antibiotic	Infection
Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .

HY-P5484

SMAP-18	Bacterial	Others
SMAP-18 is a biological active peptide. (SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-A0279

Pristinamycin Pristinamycine	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

HY-N14653

Glysperin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-N14654

Glysperin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Glysperin B has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-N14680

Glysperin C	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-126577

Dactylocycline B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria .

HY-N5184

Nocathiacin Ⅲ Nocathiacine III	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Nocathiacin III (Nocathiacine III) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N5195

Nocathiacin II Nocathiacine II	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Nocathiacin II (Nocathiacine II) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N5196

Nocathiacin I Nocathiacine I	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Nocathiacin I (Nocathiacine I) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N14899

Oxasetin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Oxasetin has medium activity against Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis (MIC is 16 μg/mL). Oxasetin has no activity against Gram-negative bacteria and fungi .

HY-165294

Amidinomycin	Structural Classification Microorganisms Antibiotics Source classification	Bacterial
Amidinomycin is mainly resistant to Gram-positive bacteria (weak) .

HY-N14497

Nocardicyclin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Nocardicyclin A is resistant to Gram-positive bacteria, mycobacterium and Nocardia .

HY-N13971

Bamicetin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Bamicetin is mainly resistant to Gram-positive bacteria and Mycobacteria .

HY-N14948

2"-N-Formimidoylsporaricin A	Structural Classification Natural Products Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
2"-N-Formimidoylsporaricin A has the activity of anti-Gram-positive bacteria and negative bacteria, and also has the antibacterial activity against the aminoglycol-resistant bacteria .

HY-N14528

Oganomycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Oganomycin A is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-N14529

Oganomycin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Oganomycin B is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-N13147

Tetromycin C5	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Tetromycin C5 is an antibiotic, that exhibits board-spectrum antibacterial activity against gram-positive bacteria and their drug-resistant bacteria .

HY-106590

Saccharocin Antibiotic KA 5685	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Saccharocin (Antibiotic KA 5685) is effective against Gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria .

HY-N14313

Nocardicyclin B	Quinones Structural Classification Microorganisms Anthraquinones Source classification	Bacterial
Nocardicyclin B is resistant to Gram-positive bacteria, mycobacterium and Nocardia .

HY-W016420

Fosfomycin sodium 5+ Cited Publications MK-0955 sodium	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Bacterial Antibiotic
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-N14118

Chloropolysporin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Chloropolysporin B has strong activity of anti-Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria .

HY-N14119

Chloropolysporin C	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Chloropolysporin C has strong activity of anti-Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria .

HY-W748035

Etamycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Etamycin A is an ester peptide antibiotic. Mainly resistant to Gram-positive bacteria and mycobacteria .

HY-N14706

Kibdelin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Kibdelin A is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14489

Neocopiamycin A	Structural Classification Natural Products Microorganisms Source classification	Bacterial Fungal
Neocopiamycin A is broad-spectrum resistant to Gram-positive bacteria, yeast and filamentous fungi .

HY-N14707

Kibdelin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Kibdelin B is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14710

Kibdelin D	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Kibdelin D is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14542

Oleficin	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Bacterial
Oleficin is resistant to Gram-positive bacteria and effective against subcutaneous transplantation of Yoshida sarcoma .

HY-N15059

Cissetin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cissetin shows activity against Gram-positive bacteria, including drug-resistant strains .

HY-N14486

Neihumicin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Neihumicin is resistant to beer Saccharomyces yeast ATCC 9763 and Penicillium italium Wehmer, but not to bacteria .

HY-N14709

Kibdelin C2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Kibdelin C2 is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N14708

Kibdelin C1	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Kibdelin C1 is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .

HY-N15119

Polymyxin S1	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Polymyxin S1 is found in Bacillus Polymyxa RS-6 and is resistant to Gram-positive bacteria .

HY-N11874

Staphyloferrin A	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .

HY-N14125

Chloroquinocin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Chloroquinocin has moderate activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) .

HY-N15019

Glycothiohexide α	Structural Classification Natural Products Microorganisms Antibiotics Source classification	Antibiotic Bacterial
Glycothiohexide α is a peptide antibiotic. Glycothiohexide α has strong activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VREF), MIC values of 0.03-0.06 μg/mL .

HY-N14191

Malonylniphimycin	Structural Classification Microorganisms Antibiotics Cyclopeptides Source classification	Antibiotic Bacterial Fungal
Malonylniphimycin is a macrolide antibiotic found in Streptomyces str. hygroscopicus B-7. Malonylniphimycin is resistant to Gram-positive bacteria, fungi and yeasts .

HY-N13941

Baciphelacin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Baciphelacin is mainly resistant to gram-positive bacteria and has the activity of inhibiting Newcastle disease virus and leukemia P-388 cells .

HY-N13885

Amythiamicin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Parasite
Amythiamicin A is an antimicrobial antibiotic against Gram-positive *bacteria* (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-N14608

Pacidamycin D	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Pacidamycin D is a Pacidamycin antibiotic. Pacidamycin D has the activity against Pseudomonas aeruginosa with a MIC of 4-16 μg/mL. it has no effect on other Gram-negative bacteria and Gram-positive bacteria, and no effect on drug-resistant pseudomonas aeruginosa .

HY-N13990

Senfolomycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Senfolomycin A has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin, Macrolide antibiotics. Senfolomycin A also has weaker effect of anti-Gram-negative bacteria .

HY-N14171

Epicorazine A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Fungal
Epicorazine A has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine A also has effect on Candida albicans with a MIC of 25 μg/mL .

HY-N13991

Senfolomycin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Senfolomycin B has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin, Macrolide antibiotics. Senfolomycin A also has weaker effect of anti-Gram-negative bacteria .

HY-N14673

Helvecardin A	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Helvecardin A is a glycopeptidtic antibiotic. Helvecardin A has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus .

HY-N13881

Amythiamicin C	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Parasite
Amythiamicin C is an antimicrobial antibiotic against Gram-positive *bacteria* (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-N14520

Pacidamycin 4N	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Pacidamycin 4N is a Pacidamycin antibiotic. Pacidamycin 4N has the activity against Pseudomonas aeruginosa with MIC of 4-16 μg/mL. it has no effect on other Gram-negative bacteria and Gram-positive bacteria, and no effect on drug-resistant pseudomonas aeruginosa .

HY-N14172

Epicorazine B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Fungal
Epicorazine B has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine B also has effect on Candida albicans with a MIC of 25 μg/mL .

HY-N14623

Paulomycin B	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Paulomycin B has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .

HY-116271

Sperabillin C	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .

HY-N12421

Paulomycin A Volonomycin A	Structural Classification Microorganisms Antibiotics Source classification	Bacterial
Paulomycin A (Volonomycin A) has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .

HY-N14470

Kigamicin A	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Kigamicin A shows activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs of 0.025-0.78 μg/mL .

Cat. No.	Product Name	Chemical Structure

HY-B1075AS

(Rac)-Fosfomycin (benzylamine)-13C3

(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin . Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-W016456S

5-Bromopentanoic-3,3,4,4 Acid-d4
5-Bromopentanoic-3,3,4,4 Acid-d₄ is the deuterium labeled 5-Bromopentanoic-3,3,4,4 Acid (HY-W016456). 5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria .

HY-10394S1

PNU-100766-d8
PNU-100766-d₈ is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .

Cat. No.	Product Name		Classification

HY-169175

CN-CC-861		Alkynes
CN-CC-861 is a broad-spectrum antibiotic. CN-CC-861 shows antibiotic activities for susceptible and multidrug-resistant bacteria. CN-CC-861 shows potent bactericidal activity in vivo .

HY-174333

CYP1A1-IN-1		Alkynes
CYP1A1-IN-1 (Compound 47) is a small-molecule cytochrome P4501A1 (CYP1A1) inhibitor. CYP1A1-IN-1 reduces the bacterial loads of methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii by enhancing macrophage phagocytosis. CYP1A1-IN-1 is promising for research of sepsis caused by multidrug-resistant (MDR) bacteria .

Cat. No.	Product Name		Classification

HY-N0717

L-Valine 4 Publications Verification (S)-Valine		Freeze-drying Protective Agents Solubilizing Agents
L-Valine (Valine) is a new nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .

HY-Z15868

5-Hydroxycytidine		Nucleosides and their Analogs C
5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli .

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