Search Result
        
        
            
                Results for "
Resistant bacteria
" in MedChemExpress (MCE) Product Catalog:
            
         
        
        
            
                
            
            
                
            
            
            
                
                    1
Biochemical Assay Reagents
 
                    
                 
            
            
                
            
            
            
            
                
            
            
            
                
                    14
Isotope-Labeled Compounds
 
                    
                 
            
            
            
                
            
            
                
            
         
        
            
            
                
                    
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Target | 
                            Research Areas | 
                            Chemical Structure | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-A0279
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Pristinamycine 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-146595
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14653
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-B1075A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MK-0955 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14680
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14654
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Glysperin B has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-126577
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N5195
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Nocathiacine II 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Nocathiacin II (Nocathiacine II) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N5184
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Nocathiacine III 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Nocathiacin III (Nocathiacine III) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N5196
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Nocathiacine I 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Nocathiacin I (Nocathiacine I) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14899
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Oxasetin has medium activity against Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis (MIC is 16 μg/mL). Oxasetin has no activity against Gram-negative bacteria and fungi .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-165294
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14497
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Nocardicyclin A is resistant to Gram-positive bacteria, mycobacterium and Nocardia .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N13971
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Bamicetin is mainly resistant to Gram-positive bacteria and Mycobacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14528
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Oganomycin A is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14948
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    2"-N-Formimidoylsporaricin A has the activity of anti-Gram-positive bacteria and negative bacteria, and also has the antibacterial activity against the aminoglycol-resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-117742
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    DA-7867 is an antibacterial compound with activity against a wide range of bacteria, including drug-resistant bacteria. DA-7867 shows promising antibacterial activity against some clinically important pathogens, including drug-resistant bacteria. It is an amide analog of Tedizolid, reflecting the potential use of tetrazoles in the development of new antibacterial agents.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14529
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Oganomycin B is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N13147
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Tetromycin C5 is an antibiotic, that exhibits board-spectrum antibacterial activity against gram-positive bacteria and their drug-resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-106590
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Antibiotic KA 5685 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saccharocin (Antibiotic KA 5685) is effective against Gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-B1075AS
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MK-0955 (benzylamine)-13C3 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    (Rac)-Fosfomycin (benzylamine)- 13C3 is the  13C labeled Fosfomycin . Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-W016420
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MK-0955 sodium 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14313
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Nocardicyclin B is resistant to Gram-positive bacteria, mycobacterium and Nocardia .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14119
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Chloropolysporin C has strong activity of anti-Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14118
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Chloropolysporin B has strong activity of anti-Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-B1075
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MK-0955 calcium 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-B0609
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MK-0955 tromethamine 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Fosfomycin (MK-0955) tromethamine is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin tromethamine shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-W748035
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14706
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kibdelin A is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-W016456
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Drug Intermediate
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14489
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Neocopiamycin A is broad-spectrum resistant to Gram-positive bacteria, yeast and filamentous fungi .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14707
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kibdelin B is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14710
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kibdelin D is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N15551
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Armeniaspirol C is a potent antibacterial agent targeting Gram-positive bacteria. Armeniaspirol C is is promising for research of infections caused by multidrug-resistant Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N15059
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cissetin shows activity against Gram-positive bacteria, including drug-resistant strains .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14542
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Oleficin is resistant to Gram-positive bacteria and effective against subcutaneous transplantation of Yoshida sarcoma .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14486
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Fungal
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Neihumicin is resistant to beer Saccharomyces yeast ATCC 9763 and Penicillium italium Wehmer, but not to bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14709
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kibdelin C2 is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14708
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kibdelin C1 is resistant to Gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as Vancomycin (HY-B0671) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-14849
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Razupenem;  SM 216601;  SMP 601 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    PTZ601 (SMP 601) is an antibiotic, which inhibits the gram-positive bacteria, including the Vancomycin (HY-B0671)-resistant Enterococcus faecium (VREF) and Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). PTZ601  exhibits antimicrobial activity in infected mouse models .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N15119
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Polymyxin S1 is found in Bacillus Polymyxa RS-6 and is resistant to Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N11874
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-128384
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Benzyldodecyldimethylammonium chloride dihydrate is a quaternary ammonium compound (QAC) and can be used as a biocide to target antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant (MDR) P. aeruginosa et. al. Benzyldodecyldimethylammonium chloride dihydrate, an antimicrobial agent, bacteriostatic or bactericidal properties depending on the concentration.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-118036
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Topoisomerase
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    ACT-387042 is a bacterial topoisomerase inhibitor with broad-spectrum activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus and penicillin- and fluoroquinolone-resistant Streptococcus pneumoniae  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-B1075R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MK-0955 calcium (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Fosfomycin (calcium) (Standard) is the analytical standard of Fosfomycin (calcium). This product is intended for research and analytical applications. Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-167651
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    TAN-1057C is a potent antibiotic which exhibits antibacterial activity against Gram-negative and Gram-positive bacteria, including Methicillin (HY-121544)-resistant Staphylococcus aureus .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N14125
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Chloroquinocin has moderate activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-126629
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-151567
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-116571
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative bacteria and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            
                                
                                    - HY-N15019
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Glycothiohexide α is a peptide antibiotic. Glycothiohexide α has strong activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VREF), MIC values of 0.03-0.06 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14191
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Malonylniphimycin is a macrolide antibiotic found in Streptomyces str. hygroscopicus B-7. Malonylniphimycin is resistant to Gram-positive bacteria, fungi and yeasts .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-122073
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Furalazine is an antimicrobial agent. Furalazine shows activity against drug-resistant strains of cholera bacteria. Furalazine has the potential for the research of cholera .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13885
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13941
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Baciphelacin is mainly resistant to gram-positive bacteria and has the activity of inhibiting Newcastle disease virus and leukemia P-388 cells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14608
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Pacidamycin D is a Pacidamycin antibiotic. Pacidamycin D has the activity against Pseudomonas aeruginosa with a MIC of 4-16 μg/mL. it has no effect on other Gram-negative bacteria and Gram-positive bacteria, and no effect on drug-resistant pseudomonas aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13990
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Senfolomycin A has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin, Macrolide antibiotics. Senfolomycin A also has weaker effect of anti-Gram-negative bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14171
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Epicorazine A has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine A also has effect on Candida albicans with a MIC of 25 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13991
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Senfolomycin B has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin, Macrolide antibiotics. Senfolomycin A also has weaker effect of anti-Gram-negative bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-139618
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    DuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14673
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Helvecardin A is a glycopeptidtic antibiotic. Helvecardin A has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P1720
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13881
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-149309
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Topoisomerase
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Topoisomerase inhibitor 2 (18C) is a bacterial topoisomeraseinhibitor that exhibits potent broad-spectrum activity against multidrug-resistant Gram-negative bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-106350
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     U-63196E;  AC-1370 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cefpimizole (U-63196E) is a broad-spectrum cephalosporin antibiotic. Cefpimizole inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole augments phagocytosis of macrophages and neutrophils  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-106350A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     U-63196E sodium; AC-1370 sodium 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cefpimizole (U-63196E) sodium is a broad-spectrum cephalosporin antibiotic. Cefpimizole sodium inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole sodium augments phagocytosis of macrophages and neutrophils  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14520
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Pacidamycin 4N is a Pacidamycin antibiotic. Pacidamycin 4N has the activity against Pseudomonas aeruginosa with MIC of 4-16 μg/mL. it has no effect on other Gram-negative bacteria and Gram-positive bacteria, and no effect on drug-resistant pseudomonas aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14172
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Epicorazine B has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine B also has effect on Candida albicans with a MIC of 25 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14623
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Paulomycin B has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-151102
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Fabimycin is a FabI inhibitor with potent antibacterial activity against gram-negative bacteria. Fabimycin is effective against drug-resistant gram-negative Infections in vivo .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-139863
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 62 is a novel redox cycling antituberculosis chemotype with potent bactericidal activity against growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-116271
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Sperabillin C is an antibacterial antibiotic with activity against both Gram-negative and Gram-positive bacteria, including resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N12421
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Volonomycin A 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Paulomycin A (Volonomycin A) has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14470
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kigamicin A shows activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs of 0.025-0.78 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-117285
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Lactoquinomycin A;  LQM-A 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Lactoquinomycin A is a quinone antibiotic. Lactoquinomycin A has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi.  Lactoquinomycin A inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013 and 0.03, respectively .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14774
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi.  Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14476
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kigamicin B shows activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs of 0.025-0.78 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14657
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Paulomycin A2 has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14106
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cinerubin R has anti-Gram-positive bacteria and inhibition of tumor cell activity, and its inhibition effect on multidrug resistant (MDR) cells is the same as that on protocells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14675
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Helvecardin B is a glycopeptidtic antibiotic. Helvecardin B has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-161300
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 191 (compound 11a) is a potent semi-synthetic antibiotic. Antibacterial agent 191 exhibits preferable metabolic stability .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-149089
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 138 has excellent antibacterial activity to multi-drug resistant bacteria. Antibacterial agent 138 inhibits bacterial protein synthesis but bacterial cell walls .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-116168
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Aldecalmycin is an antibiotic showing antimicrobial activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs values of 6.25-25 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P1649B
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     NAB741 acetate 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P1649
 
                                    - 
                                        
                                            
                                                
                                                    
                                                        
                                                            SPR741
                                                            
                                                        
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    3 Publications Verification 
                                                                
                                                             
                                                        
                                                     
                                                    NAB741 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-12459
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Pyrindamycin B is an antibiotic, actives against gram-positive and gram-negative bacterias, and exhibits strong therapeutic effects against both agent-sensitive and resistant cells of P388 leukemia in mice .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113759
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saquayamycin A has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin A has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-155682
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 150 (compound 5g) is an antibacterial agent with potent antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria (MIC values ranging from 1-32 μg/mL). Antibacterial agent 150 can increase survival rate of MRSA (Methicillin-resistant Staphylococcus aureus)-infected mice .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P1649A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     NAB741 TFA 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P5691
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P10411
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-112959
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     TD-6424 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Telavancin (TD-6424) is a semisynthetic lipoglycopeptide vancomycin-derivative, is a novel antimicrobial agent developed by Theravance for overcoming resistant Gram-positive bacterial infections, specifically methicillin-resistant Staphylococcus aureus (MRSA). Telavancin disrupts cell membrane integrity, can be used for research of complicated skin and skin structure infections (cSSSIs) caused by Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N11879
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    6-C-Methylquercetin-3,4'-dimethyl etheris a flavonol derivative isolated from the leaves of Bauhinia thonningii Schum. 6-C-Methylquercetin-3,4'-dimethyl ether has antibacterial activity against Gram-negative multidrug-resistant bacteria and against methicillin-resistant Staphylococcus aureus (MRSA) strains .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-173478
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Topoisomerase
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    OSUAB-0284 is a bacterial topoisomerase inhibitor. OSUAB-0284 has significant anti-staphylococcal activity, especially against methicillin-resistant Staphylococcus aureus (MRSA). OSUAB-0284 exerts its antibacterial effect by inhibiting bacterial topoisomerase. OSUAB-0284 can be used to study infections caused by drug-resistant bacteria such as MRSA .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-167669
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Tioxacin is an orally active bactericide agent. Tioxacin combined with aliphatic amines has activities against G(+) and G (-) bacteria, including Escherichia coli resistant to Nalidixic acid (HY-B0398) and Pseudomonas aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113771
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saquayamycin C has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin C has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P10210
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-A0248B
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-105048A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-169175
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    CN-CC-861 is a broad-spectrum antibiotic. CN-CC-861 shows antibiotic activities for susceptible and multidrug-resistant bacteria. CN-CC-861 shows potent bactericidal activity in vivo .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-173080
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 267 (Compound h19) is a pleuromutilin derivative with a potent antibacterial activity on Gram-positive bacteria. Antibacterial agent 267 shows an antibacterial activity in methicillin-resistant Staphylococcus aureus (MRSA)-infected mouse models .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13870
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saquayamycin A1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin A1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13868
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saquayamycin C1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin C1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-W024297
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    VP-4509, an anti-methicillin‐resistant Staphylococcus aureus (MRSA) agent, with the MIC of 49.3 µM. VP-4509 also possesses high antibacterial activity towards gram-negative bacteria P. aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-126802
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saquayamycin B1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin B1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-19964
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Potassium clavulanate:cellulose (1:1) 
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Potassium clavulanate cellulose (Potassium clavulanate:cellulose (1:1)) is a mixture of potassium clavulanate and cellulose, is a bacterial β-lactamase inhibitor.  Clavulanate potassium is a form of Clavulanic acid. Clavulanate potassium fights bacteria that resistant to penicillins and other antibiotics.  Potassium clavulanate with the combination of amoxicillin can be used for the research of different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-A0248C
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Polymyxin B2 Sulfate is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 Sulfate kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 Sulfate can be used in antibiotic development and treatment of drug-resistant strains .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-19915A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MRX-4 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Contezolid acefosamil (MRX-4) is the orally active proagent of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14955
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    3-O-α-D-Forosaminyl-(+)-griseusin is a memberof naphthoquinone antibiotic. 3-O-α-D-Forosaminyl-(+)-griseusin is active against Gram-positive bacteria including methicillin-resistant strain of Staphylococcus aureus (MRSA) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-123347
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Endogenous Metabolite
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to Lydicamycin (HY-125414). It is active against Gram-positive bacteria (MICs=0.39-3.13 μg/mL), including methicillin-resistant S. aureus strains (MIC=3.13 μg/mL), but is ineffective against Gram-negative bacteria (MICs=>50 μg/mL).
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-121295
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-146811
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    HSGN-94 is a potent antimicrobial agent with lipoteichoic acid (LTA) biosynthesis inhibition. HSGN-94 inhibits drug-resistant Gram-positive bacteria with MIC values of 0.25-2 μg/mL. HSGN-94 inhibits biofilm formation of MRSA and Vancomycin-resistant Enterococci. HSGN-94 also inhibits pro-inflammatory cytokines, exhibits in vivo efficacy in an MRSA murine wound infection model .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-157482
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    EBP-59 is a bacterial inhibitor with antibiofilm activity against Gram-positive bacteria. EBP-59 is effective against Staphylococcus aureus and MRSA (methicillin–resistant staphylococcus aureus). EBP-59 can be used to study bacterial infections .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N7047
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-19915
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MRX-I 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Monoamine Oxidase
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Contezolid (MRX-I), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI)  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-127155
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kigamicin C is an anti-tumor antibiotic that selectively kills pancreatic cancer PANC-1 cells only in nutrient-poor conditions. Kigamicin C has antimicrobial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-124679A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    (R)-DS86760016 is the R-enantiomer of DS86760016 (HY-124679). DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-10394
 
                                    - 
                                        
                                            
                                                
                                                    
                                                        
                                                            Linezolid
                                                            
                                                        
                                                        
                                                            
                                                                
                                                                    Maximum Cited Publications 
                                                                    42 Publications Verification 
                                                                
                                                                
                                                                
                                                             
                                                        
                                                     
                                                    PNU-100766 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0593
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     GR20263 
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-174333
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Cytochrome P450
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cardiovascular Disease
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    CYP1A1-IN-1 (Compound 47) is a small-molecule cytochrome P4501A1 (CYP1A1) inhibitor. CYP1A1-IN-1 reduces the bacterial loads of methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii by enhancing macrophage phagocytosis. CYP1A1-IN-1 is promising for research of sepsis caused by multidrug-resistant (MDR) bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0317F
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Calcium Channel
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amlodipine hydrochloride is a biologically active drug used to lower blood pressure and prevent chest pain. Amlodipine hydrochloride has shown synergistic effects with antimicrobial drugs in in vitro studies, especially against carbene peptide-resistant Acinetobacter baumannii. Amlodipine hydrochloride can be used in combination with other antibiotics to enhance the inhibitory effect against resistant bacteria. The use of amlodipine hydrochloride helps reduce the dosage requirements of the drug, reduce toxic effects, and delay the emergence of drug resistance .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2805
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0593A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     GR20263 pentahydrate 
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate  is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-122523
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Tetromycin A is a tetronic acid-based antibiotic. It reportedly has pronounced activity against Gram-positive bacteria, including methicillin-resistant S. aureus. Related tetromycin derivatives have been found to have anti-trypanosomal activity and inhibit the cysteine protease cathepsin L with Ki values in the low micromolar range.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P10540
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Pantinin-2 is a cysteine-free toxic peptide found in the emperor scorpion (paninus imperator). Pantinin-2 has high activity against Gram-positive bacteria but weak activity against Gram-negative bacteria. Pantinin-2 also exhibits activity against Candida tropicalis and has relatively mild hemolytic activity against human erythrocytes. Pantinin-2 can be used in the development of antimicrobial drugs for drug-resistant pathogens .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113640
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P1708
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BRN 537924;  NSC 657143 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC=25 μg/mL), and Gram-negative bacteria, including mutant forms of E. coli and P. aeruginosa (MICs=200 μg/mL); however, it is not inhibitory to fungi.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0509AR
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BAY 41-6551 (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amikacin (Standard) is the analytical standard of Amikacin. This product is intended for research and analytical applications. Amikacin (BAY 41-6551), a semisynthetic analog of kanamycin, is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin (BAY 41-6551) is ototoxic and nephrotoxic  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-W016456S
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    5-Bromopentanoic-3,3,4,4 Acid-d4 is the deuterium labeled 5-Bromopentanoic-3,3,4,4 Acid (HY-W016456). 5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-19915B
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     MRX-4 sodium 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Monoamine Oxidase
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Contezolid acefosamil sodium (MRX-4), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid acefosamil sodium (MRX-4) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI)  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-161980
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Topoisomerase
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Topoisomerases/ribosomes-IN-1 (compound 30f) is an inhibitor of ribosomes and topoisomerases, and has inhibitory effects on constitutively macrolide-resistant bacteria. Topoisomerases/ribosomes-IN-1 can inhibit bacterial protein synthesis (IC50: 0.647 μM) and DNA replication (IC50: 0.218 μM) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-162959
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Topoisomerase
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    BWC0977 is a potent bacterial topoisomerase inhibitor that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 exhibits a minimum inhibitory concentration (MIC90) of 0.03-2 µg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0509A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BAY 41-6551 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amikacin (BAY 41-6551) is a semisynthetic kanamycin analog that is active against most Gram-negative bacteria, including gentamicin- and tobramycin-resistant strains. Significant inhibitory effect. Amikacin is ototoxic and nephrotoxic. Amikacin can be used in bacteriostatic, anti-cancer and analgesic studies     .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-10393
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     PNU-100592 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of chloramphenicol (HY-B0239) and lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P3328
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-117974
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     ETX2514 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P3328A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-172734
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    FG-2101 is a selective and orally active non-hydroxamate LpxC inhibitor with an IC50 of ~1 nM. FG-2101 exhibits exquisite selectivity over other bacterial and human metalloenzymes. FG-2101 can be used for the study of Gram-negative bacteria infections including drug-resistant strains .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-69174
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113678
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Colistin is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P11100
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    PepW is a potent antimicrobial peptide targeting the capsule of multidrug-resistant Klebsiella pneumoniae (MIC=2-8 μM). PepW achieves bactericidal activity via capsule polysaccharide aggregation and structural disruption. PepW is promising for research of infectious diseases caused by Gram-negative bacteria (e.g., pneumonia, sepsis) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14530
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cremeomycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremeomycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14144
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cremimycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremimycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14484
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kigamicin D shows activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs of 0.025-0.78 μg/mL. Kigamicin D also shows effect against L-1210 LB32T and other genera tumor cells with IC50 of 1 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-A0097
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Antibiotic MDL-507;  MDL-507 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-A0097A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Antibiotic MDL-507 sodium; MDL-507 sodium 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        HIV
                                                    
                                                        SARS-CoV
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-161263
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-Z15868
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Nucleoside Antimetabolite/Analog
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-164036
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Lolamicin is an orally effective inhibitor that specifically targets the Gram-negative bacteria lipoprotein transport system LolCDE complex. It selectively inhibits the transmembrane transport of outer membrane lipoproteins by competitively binding to lipoprotein binding sites. Lolamicin destroys the integrity of the bacterial outer membrane, leading to cell death, and has both bactericidal and antibacterial activity. It has significant effects on multidrug-resistant Enterobacteriaceae pathogens (such as Escherichia coli and Klebsiella pneumoniae). Lolamicin can be used to inhibit the study of acute pneumonia, sepsis and other infections caused by Gram-negative bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P10539
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Kanamycin A 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0593R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     GR20263 (Standard) 
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Ceftazidime (Standard) is the analytical standard of Ceftazidime. This product is intended for research and analytical applications. Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-10394R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     PNU-100766 (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B1924
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     N-Demethylvancomycin monohydrochloride; NVCM monohydrochloride 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Norvancomycin hydrochloride is a cell wall synthesis inhibitor targeting peptidoglycan precursors of Gram-positive bacteria and cannot pass the blood-brain barrier. Norvancomycin hydrochloride can competitively bind to peptidoglycan precursors, irreversibly inhibit bacterial cell wall synthesis, and exert antibacterial activity. Norvancomycin hydrochloride is mainly used in the study of Gram-positive bacterial infections, especially infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE). Norvancomycin hydrochloride can also be incorporated into the bionic calcium phosphate coating of titanium implants to enhance antibacterial activity and inhibit postoperative orthopedic infections  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Kanamycin A sulfate 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-129454
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Antibiotic TPU-0037-A 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    TPU-0037A is an antibiotic and a congener of lydicamycin. It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs=1.56-12.5 μg/mL), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs=>50 μg/mL).
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-115693
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    CAP 3 is a cholic acid-peptide conjugate (CAP) antimicrobial agent. CAP 3 effectively inhibits Gram-negative bacteria, with MIC99 (minimum inhibitory concentration for 99% bacterial killing) values of 8 μM, 16 μM, and 16 μM against E. coli, Klebsiella pneumoniae and Acinetobacter baumannii, respectively. CAP 3 exerts its antibacterial effects by disrupting the structural integrity of the bacterial lipopolysaccharide (LPS) outer membrane. CAP 3 rapidly kills bacteria, inhibits biofilm formation, and effectively combats drug-resistant strains and persistent bacterial infections .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-12770R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Mebeverine metabolite Mebeverine alcohol (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Drug Metabolite
                                                    
                                                 | 
                                                
                                                    
                                                        Neurological Disease
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Mebeverine alcohol (Standard) is an analytical standard for Mebeverine alcohol. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of Chloramphenicol (HY-B0239) and Lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-170991
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    C12-rrw-NH2 (Compound Lip7) is an antibacterial agent against gram-positive bacteria, especially against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). C12-rrw-NH2 induces bacterial death  via depolarizing the bacterial cytoplasmic membrane, disrupting the integrity of the bacterial membrane, leading to leakage of nucleic acid and protein and promoting the generation of Reactive Oxygen Species. C12-rrw-NH2 is potential to be used for research of developing high-stability antimicrobial peptides .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-130282
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Ianthelliformisamine C ditrifluoroacetate is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine C ditrifluoroacetate has been shown to improve the efficacy of doxycycline against Pseudomonas aeruginosa. Ianthelliformisamine C ditrifluoroacetate was prepared using peptide coupling, resulting in high chemical yields of 27 to 91%. Ianthelliformisamine C ditrifluoroacetate exhibits its mechanism of action by inducing ATP efflux and causing membrane depolarization in bacterial cells.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0509
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BAY 41-6551 hydrate 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0593AR
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     GR20263 pentahydrate (Standard) 
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Ceftazidime (pentahydrate) (Standard) is the analytical standard of Ceftazidime (pentahydrate). This product is intended for research and analytical applications. Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate  is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-124679
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. DS86760016 inhibits LeuRS enzymes from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, with IC50s of 0.38, 0.62, and 0.16 μM, respectively  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-10394S1
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     PNU-100766-d8 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-130280
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Ianthelliformisamine A TFA is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine A TFA exhibits bactericidal activity against Staphylococcus aureus with an IC50 value of 3.8 μM (minimum inhibitory concentration = 25 μM). The biological activity of Ianthelliformisamine A TFA is derived from the structural variation of its synthetic derivatives and its coupling reaction with different amino ester derivatives .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16485
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     TD-6424 hydrochloride 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Telavancin hydrochloride is the hydrochloride form of Telavancin (HY-112959). Telavancin hydrochloride is a semisynthetic derivative of vancomycin, and exhibits antibacterial efficacy through inhibition of cell wall synthesis and disruption of cell membrane barrier function. Telavancin hydrochloride is efficient against antibiotic resistant S. aureus strains MRSA, VISA, and hVISA. Telavancin hydrochloride attenuates gram positive bacteria induced complicated skin and skin structure infections (cSSSI) .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16745A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     KRP-AM1977 hydrochloride 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P3349
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-119387
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Chevalone B was isolated from the ethyl acetate extract of the marine sponge-associated fungus Aspergillus similanensis. The structure of Chevalone B was confirmed by 1D and 2D NMR spectroscopy. Chevalone B showed antimicrobial activity against Gram-positive and Gram-negative bacteria, Candida albicans, and multidrug-resistant strains from the environment. Studies on Chevalone B have shown its potential value in antimicrobial applications.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P11102
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                        HIV
                                                    
                                                        Parasite
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Temporin-Sha is an antibacterial peptide with extensive biological activity. Temporin-Sha exhibits broad-spectrum antibacterial activity (e.g., against L. ivanovii, MIC = 6.25 μM), and is effective against Gram-negative bacteria (such as Escherichia coli, MIC = 10 μM), including drug-resistant strains (such as Methicillin (HY-121544)-resistant Staphylococcus aureus). Temporin-Sha also has inhibitory effects on Candida albicans (MIC = 25 μM), Saccharomyces cerevisiae (MIC = 12 μM), the pre-flagellated and non-flagellated forms of Leishmania infantum (IC50 = 5-20 μM), and Trypanosoma cruzi (IC50 = 17 μM). Temporin-Sha exhibits antiviral activity against HSV-1 and has anti-cancer effects (cytotoxicity against breast cancer cells MCF-7 and lung cancer cells H460, etc.)     .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-121348
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     U-47929 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                
                                                    Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases . 
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0509B
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BAY 41-6551 disulfate 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Kanamycin A (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (Standard) is the analytical standard of Kanamycin. This product is intended for research and analytical applications. Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia[1][2][3][4].
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-107813
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BAY 41-6551 sulfate 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P3348
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-121120
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N6680
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections [1][2].
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-126735
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC50 of 0.15 and 0.15 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-139554A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     KBP-7072 TFA 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-I1124
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     L-VALINE-2,3,4,4,4,5,5,5-d8 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-d8 is a deuterated form of L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P0263R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16764A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     JNJ-Q2 hydrochloride 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Acorafloxacin hydrochloride (JNJ-Q2  hydrochloride) is a broad-spectrum fluoroquinolone anti-bacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia . 
Acorafloxacin hydrochloride (Avarofloxacin ) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value . 
Acorafloxacin hydrochloride (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566AR
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Kanamycin A sulfate (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-155060
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antibacterial agent 144 (compound 8e) is an antibacterial agent,with better effect against multi-resistant Staphylococcus aureus than Chloromycin and Amoxicillin (HY-B0467A). Antibacterial agent 144 destroys the cytoplasmic membrane of bacteria,and inhibits the biofilms formation. Antibacterial agent 144 binds to HSA (Kd=13.2 μM),and exerts bactericidal efficacy. Antibacterial agent 144 also binds with DNA to for supramolecular complex to obstruct DNA replications .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-139554
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     KBP-7072 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-100589
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Sch 21420 sulfate 
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cardiovascular Disease
                                                    
                                                        Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Isepamicin sulfate (Sch 21420 sulfate) is a broad-spectrum aminoglycoside antibiotic. Isepamicin sulfate has considerable antimicrobial activity against some Gram-negative non-fermenting bacteria that are highly resistant to antibiotics. Isepamicin sulfate inhibits writhing reactions induced by Acetic acid (HY-Y0319), regulates vascular blood flow and blood pressure, and inhibits spontaneous uterine movements. Isepamicin sulfate has antidiuretic and blood sugar-raising effects. Isepamicin sulfate can be used in seizure research  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-178111
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    AcrB-IN-6 is an effective AcrB inhibitor. AcrB-IN-6 The compound inhibits the function of bacterial multidrug efflux pumps, thereby significantly enhancing the antibacterial activity of various antibiotics. AcrB-IN-6 achieves 32-fold MIC reductions in wild-type E. coli BW25113. AcrB-IN-6 exhibits excellent synergistic antibacterial effects, low cytotoxicity and hemolytic properties. AcrB-IN-6 can be used for researching anti-resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-15N 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 15N ((S)-Valine- 15N) is the  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16764
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     JNJ-Q2 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial agent being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia with oral activity. Avarofloxacin (JNJ-Q2) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value. Avarofloxacin (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S6
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-13C5 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5 ((S)-Valine- 13C5) is the  13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine (Standard) ((S)-Valine (Standard)) is the analytical standard of L-Valine (HY-N0717). This product is intended for research and analytical applications. L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S8
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-d1 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-Y1826
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    IITR01324 is an antimicrobial agent. IITR01324 has antimicrobial activity against Escherichia coli (MIC = 3.58 mg/L) and other Gram-negative bacteria (Shigella flexneri: MIC = 3.58 mg/L; Cronobacter sakazakii: MIC = 28.63 mg/L). IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases. IITR01324 can be used to study the development of new antimicrobial drugs, especially against multidrug-resistant (MDR) pathogens .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-146460
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P5484
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SMAP-18 is a biological active peptide. (SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.)
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S5
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-13C 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-2- 13C ((S)-Valine-2- 13C) is the  13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S4
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-1-13C 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-1- 13C ((S)-Valine-1- 13C) is the  13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-B0509BR
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     BAY 41-6551 disulfate (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Amikacin (disulfate) (Standard) is the analytical standard of Amikacin (disulfate). This product is intended for research and analytical applications. Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin-and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S9
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-15N,d8 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 15N,d8 ((S)-Valine- 15N,d8) is the deuterium and  15N labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N6680R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-150260
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SA09-Cu is a noncompetitive and potent NDM-1 inhibitor with an IC50 of 9.6 nM. SA09-Cu can convert NDM-1 into an inactive state by oxidizing the Zn(II)-thiolate site of the enzyme and avoids to be reduced by intracellular thiols of bacteria. SA09-Cu exhibits excellent inhibition against a series of clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) in restoring the Meropenem (HY-13678) effect, and slows down the development of carbapenem resistance .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S1
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-13C5,15N 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5, 15N ((S)-Valine- 13C5, 15) is the  13C- and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-117746
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    KSK120 is a potent inhibitor of drug-resistant infections with specific activity against Chlamydia trachomatis (C. trachomatis). KSK120 inhibits the developmental cycle of C. trachomatis, thereby reducing the infectivity of progeny bacteria. KSK120 targets the glucose-6-phosphate (G-6P) metabolic pathway of C. trachomatis, showing its potential application in antimicrobial inhibition. The mechanism of KSK120 may involve inhibition of the transcriptional machinery, which provides new ideas for the development of specific drugs against C. trachomatis infection .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S7
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-1-13C,15N 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-1- 13C, 15N ((S)-Valine-1- 13C, 15N) is the  13C- and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-139554AR
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     KBP-7072 TFA (Standard) 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Reference Standards
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Zifanocycline (TFA) (Standard) is the analytical standard of Zifanocycline (TFA). This product is intended for research and analytical applications. Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections[1][2].
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113703
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    PD117588 is a quinolone antibacterial agent with a broad range of antibacterial activity. PD117588 exhibits excellent activity against a variety of Gram-positive and Gram-negative bacteria from cancer patients, especially against all Gram-positive strains, including methicillin-resistant Staphylococcus aureus, coagulase-negative Staphylococci, and Enterococci. PD117588 is also very effective against most Gram-negative bacilli, although ciprofloxacin shows stronger activity against Pseudomonas aeruginosa. Compared with other quinolone antibiotics, the minimum inhibitory concentration of PD117588 outperforms most of the tested microorganisms, including imipenem and ceftazidime .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S2
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-13C5,15N,d8 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5, 15N,d8 ((S)-Valine- 13C5, 15N,d8) is the deuterium,  13C-, and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717S3
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     (S)-Valine-13C5,15N,d2 
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                        Arginase
                                                    
                                                        Akt
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5, 15N,d2 ((S)-Valine- 13C5, 15N,d2) is the deuterium,  13C-, and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-Y1826R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    IITR01324 (Standard) is the analytical standard of IITR01324. This product is intended for research and analytical applications. IITR01324 is an antimicrobial agent. IITR01324 has antimicrobial activity against Escherichia coli (MIC=3.58 mg/L) and other Gram-negative bacteria (Shigella flexneri: MIC=3.58 mg/L; Cronobacter sakazakii: MIC=28.63 mg/L). IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases. IITR01324 can be used to study the development of new antimicrobial drugs, especially against multidrug-resistant (MDR) pathogens .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P11085
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    WLBU2 is a engineered cationic antimicrobial peptide (eCAP) that overcomes the environmental sensitivity of natural antimicrobial peptides (AMPs). WLBU2 exhibits rapid bactericidal effect, with the MIC values of ≤ 10 μM against both Gram-negative and Gram-positive bacteria including MRSA, vancomycin-resistant enterococci, K. pneumoniae, E.aerogenes, E. cloacae, Escherichia coli, et, al. WLBU2 prevents P. aeruginosa biofilm growth and retains its activity in an environment rich in mucus, low pH and high salt concentrations without negative effects on human airway epithelial cells. WLBU2 can be used for the studies of cystic fibrosis (CF) and Pseudomonas aeruginosa infections  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-42034
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Dihydroquinine 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        Protein Arginine Deiminase
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-107833
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). A40926 irreversibly inhibits cell wall synthesis by competitively binding to this target, and has high bactericidal activity against Gram-positive bacteria (such as Staphylococcus, Streptococcus) and Neisseria gonorrhoeae, with MIC=0.06-2 μg/mL, and is also effective against penicillin-resistant strains. A40926 blocks peptidoglycan cross-linking, destroys cell wall integrity, and causes bacterial lysis and death. A40926 has a fat-soluble fatty acid structure, which can increase serum concentrations and prolong the duration of action (e.g., the terminal half-life in rats is 61.22 h)  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-42034R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Dihydroquinine (Standard) 
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        Protein Arginine Deiminase
                                                    
                                                 | 
                                                
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-135748A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Toll-like Receptor (TLR)
                                                    
                                                        Apoptosis
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Poly (I:C):Kanamycin (1:1) sodium is an isometric complex of Poly (I:C) (HY-135748) and Kanamycin (HY-16566). Poly(I:C) sodium, a synthetic analog of double-stranded RNA, is a TLR3 and retinoic acid-inducible gene I receptor (RIG-I and  b>MDA5) agonist. Poly(I:C) sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses and induce apoptosis in cancer cells  . Kanamycin is an orally active antibacterial agent (Gram-negative/positive bacteria) that inhibits translocation and causes miscoding by binding to the 70S ribosomal subunit. Kanamycin shows good inhibitory activity against Mycobacterium tuberculosis (susceptible and drug-resistant) and Klebsiella pneumoniae, and can be used in the research of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-121195
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     PC-904 
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N8501
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities. It is active against the fungi C. albicans and C. neoformans, as well as the bacteria E. coli, S. aureus, and methicillin-resistant S. aureus (MRSA; IC50s=3.94, 0.6, 2.21, 4.55, and 2.21 μg/mL, respectively).2 Emestrin is a chemokine (C-C motif) receptor 2 (CCR2) antagonist (IC50=5.4 μM in a radioligand binding assay using isolated human monocytes).3 Emestrin (0.1 μg/mL) induces apoptosis in HL-60 cells. It induces heart, thymus, and liver tissue necrosis in mice when administered at doses ranging from 18 to 30 mg/kg.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2736
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        COX
                                                    
                                                        Interleukin Related
                                                    
                                                        Bacterial
                                                    
                                                        JNK
                                                    
                                                        ERK
                                                    
                                                        p38 MAPK
                                                    
                                                        STAT
                                                    
                                                        Apoptosis
                                                    
                                                        NO Synthase
                                                    
                                                        Nuclear Factor of activated T Cells (NFAT)
                                                    
                                                        Lactate Dehydrogenase
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        SOD
                                                    
                                                        Akt
                                                    
                                                        Caspase
                                                    
                                                        Bcl-2 Family
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Neurological Disease
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    3′,4′,7-Trihydroxyflavone is an orally active inhibitor of OXA-48 (IC50 = 1.89 μM) and COX-1 (IC50 = 36.37 μM). 3′,4′,7-Trihydroxyflavone exhibits antioxidant and anti-inflammatory properties, inhibiting the release of inflammatory cytokines such as IL-6, IL-8, and TNF-α. 3′,4′,7-Trihydroxyflavone inhibits H2O2-induced neuronal apoptosis and ROS accumulation, and exerts anti-neuroinflammatory effects by suppressing the JNK-STAT1 pathway. 3′,4′,7-Trihydroxyflavone exhibits antimicrobial and antibiotic-modifying activities against multidrug-resistant Gram-negative enteric bacteria. 3′,4′,7-Trihydroxyflavone inhibits RANKL-induced osteoclast formation via NFATc1. 3′,4′,7-Trihydroxyflavone activates the CREB-BDNF axis and restores scopolamine (HY-N0296)-induced memory deficits in mice         .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                        
                 
            
            
            
                
                    
                    
                        
                            
                            - 
                                
                                    - 
                                        HY-L142
                                    
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                                
                                                    
                                                        134 compounds
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                      Tuberculosis (TB), usually caused by bacteria (Mycobacterium tuberculosis), is an infectious disease that mainly affects the lungs. According to the statistics of the World Health Organization (WHO), 10 million people suffer from tuberculosis every year, and 1.5 million people die of tuberculosis every year, which makes tuberculosis the number one killer of infectious diseases. 
 Tuberculosis can be cured through the standard 6-month course of treatment of four kinds of antibiotics. Common drugs include rifampicin and isoniazid. In some cases, TB bacteria do not respond to standard drugs, that is, patients with drug-resistant tuberculosis. The treatment of drug-resistant tuberculosis takes longer and is more complex. In the face of the resurgence of tuberculosis in the world and the rapid emergence of multi drug resistant tuberculosis, it is very important to develop new anti-tuberculosis drugs or new clinical treatment schemes for existing anti mycobacterium drugs.  
MCE supplies a unique collection of 134 compounds with clear anti-tuberculosis activity. MCE Anti-tuberculosis Compound Library is a useful tool for anti-tuberculosis related research and anti-tuberculosis drug development p>
                                                  | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - 
                                        HY-L049
                                    
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                                
                                                    
                                                        1,674 compounds
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                     Antibacterial agents are a group of materials that fight against pathogenic bacteria. Thus, by killing or reducing the metabolic activity of bacteria, their pathogenic effect in the biological environments will be minimized. The most widely used antibacterial agents exert their effects on bacterial cell wall synthesis, protein synthesis, DNA replication and metabolic pathways. However, resistance to antimicrobial agents has become a major source of morbidity and mortality worldwide. The main mechanisms of resistance are limiting uptake of a drug, modification of a drug target, inactivation of a drug, and active efflux of a drug. Therefore, it is an urgent need to develop new drugs targeted at resistant organisms. 
MCE offers a unique collection of 1,674 compounds with validated antibacterial activities. MCE antibacterial compound library is an effective tool for drug repurposing screening, combination screening and biological investigation. 
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                        
                    
                 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Type | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-69174
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microbial Culture
                                                            
                                                        
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition.
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                        
                    
                 
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Target | 
                            Research Area | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-P1649B
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     NAB741 acetate 
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate  .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P1649
 
                                    - 
                                        
                                            
                                                
                                                    
                                                        SPR741
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    3 Publications Verification 
                                                                
                                                             
                                                        
                                                     
                                                    NAB741 
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741  .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-A0248B
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P1720
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P1649A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     NAB741 TFA 
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA  .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P5691
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P10411
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P10210
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-105048A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P10540
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Pantinin-2 is a cysteine-free toxic peptide found in the emperor scorpion (paninus imperator). Pantinin-2 has high activity against Gram-positive bacteria but weak activity against Gram-negative bacteria. Pantinin-2 also exhibits activity against Candida tropicalis and has relatively mild hemolytic activity against human erythrocytes. Pantinin-2 can be used in the development of antimicrobial drugs for drug-resistant pathogens .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P3328
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P3328A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P11100
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    PepW is a potent antimicrobial peptide targeting the capsule of multidrug-resistant Klebsiella pneumoniae (MIC=2-8 μM). PepW achieves bactericidal activity via capsule polysaccharide aggregation and structural disruption. PepW is promising for research of infectious diseases caused by Gram-negative bacteria (e.g., pneumonia, sepsis) .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P10539
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P3349
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P11102
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Fungal
                                                        
                                                    
                                                        
                                                        
                                                            HIV
                                                        
                                                    
                                                        
                                                        
                                                            Parasite
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Temporin-Sha is an antibacterial peptide with extensive biological activity. Temporin-Sha exhibits broad-spectrum antibacterial activity (e.g., against L. ivanovii, MIC = 6.25 μM), and is effective against Gram-negative bacteria (such as Escherichia coli, MIC = 10 μM), including drug-resistant strains (such as Methicillin (HY-121544)-resistant Staphylococcus aureus). Temporin-Sha also has inhibitory effects on Candida albicans (MIC = 25 μM), Saccharomyces cerevisiae (MIC = 12 μM), the pre-flagellated and non-flagellated forms of Leishmania infantum (IC50 = 5-20 μM), and Trypanosoma cruzi (IC50 = 17 μM). Temporin-Sha exhibits antiviral activity against HSV-1 and has anti-cancer effects (cytotoxicity against breast cancer cells MCF-7 and lung cancer cells H460, etc.)     .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P3348
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P0263R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Reference Standards
                                                        
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Fungal
                                                        
                                                    
                                                        
                                                        
                                                            Antibiotic
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P5484
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    SMAP-18 is a biological active peptide. (SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.)
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-P11085
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Bacterial
                                                        
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    WLBU2 is a engineered cationic antimicrobial peptide (eCAP) that overcomes the environmental sensitivity of natural antimicrobial peptides (AMPs). WLBU2 exhibits rapid bactericidal effect, with the MIC values of ≤ 10 μM against both Gram-negative and Gram-positive bacteria including MRSA, vancomycin-resistant enterococci, K. pneumoniae, E.aerogenes, E. cloacae, Escherichia coli, et, al. WLBU2 prevents P. aeruginosa biofilm growth and retains its activity in an environment rich in mucus, low pH and high salt concentrations without negative effects on human airway epithelial cells. WLBU2 can be used for the studies of cystic fibrosis (CF) and Pseudomonas aeruginosa infections  .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                        
                    
                 
            
            
            
            
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Category | 
                            Target | 
                            Chemical Structure | 
                        
                    
                    
                            
                                
                                    - HY-N14470
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-117285
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Lactoquinomycin A;  LQM-A 
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Other Antibiotics
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Lactoquinomycin A is a quinone antibiotic. Lactoquinomycin A has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi.  Lactoquinomycin A inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013 and 0.03, respectively .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14774
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Other Antibiotics
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi.  Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14476
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14657
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14106
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14675
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-116168
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113759
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N11879
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113771
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13870
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N13868
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-126802
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14955
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N7047
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-127155
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2805
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-113678
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Colistin is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14530
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                                Natural Products
                                                            
                                                            
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Cremeomycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremeomycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14144
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N14484
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                                Natural Products
                                                            
                                                            
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kigamicin D shows activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs of 0.025-0.78 μg/mL. Kigamicin D also shows effect against L-1210 LB32T and other genera tumor cells with IC50 of 1 μg/mL .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-A0097
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-A0097A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Antibiotic MDL-507 sodium; MDL-507 sodium 
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Polyphenols
                                                            
                                                        
                                                            
                                                            
                                                                Endogenous metabolite
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        HIV
                                                    
                                                        SARS-CoV
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566A
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-119387
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Other Terpenoids
                                                            
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Terpenoids
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Chevalone B was isolated from the ethyl acetate extract of the marine sponge-associated fungus Aspergillus similanensis. The structure of Chevalone B was confirmed by 1D and 2D NMR spectroscopy. Chevalone B showed antimicrobial activity against Gram-positive and Gram-negative bacteria, Candida albicans, and multidrug-resistant strains from the environment. Studies on Chevalone B have shown its potential value in antimicrobial applications.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-121348
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     U-47929 
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Other Antibiotics
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                 | 
                                            
                                            
                                                
                                                    Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases . 
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Kanamycin A (Standard) 
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (Standard) is the analytical standard of Kanamycin. This product is intended for research and analytical applications. Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia[1][2][3][4].
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-121120
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Beta-lactam Antibiotics
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N6680
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-P0263R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                                Natural Products
                                                            
                                                            
                                                        
                                                            
                                                            
                                                                Animals
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Fungal
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia    .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-16566AR
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0717R
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N6680R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Macrolide Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Antibacterial
                                                            
                                                        
                                                            
                                                            
                                                                Disease Research
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-42034
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-42034R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     Dihydroquinine (Standard) 
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Alkaloids
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Rubiaceae
                                                            
                                                        
                                                            
                                                            
                                                                Cinchona calisaya Wedd.
                                                            
                                                        
                                                            
                                                            
                                                                Quinoline Alkaloids
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        Protein Arginine Deiminase
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2736
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Flavonoids
                                                            
                                                        
                                                            
                                                            
                                                                Classification of Application Fields
                                                            
                                                        
                                                            
                                                            
                                                                Flavones
                                                            
                                                        
                                                            
                                                            
                                                                Leguminosae
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Other Diseases
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Polyphenols
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                            
                                                            
                                                                Vicia faba L.
                                                            
                                                        
                                                            
                                                            
                                                                Disease Research Fields
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Beta-lactamase
                                                    
                                                        COX
                                                    
                                                        Interleukin Related
                                                    
                                                        Bacterial
                                                    
                                                        JNK
                                                    
                                                        ERK
                                                    
                                                        p38 MAPK
                                                    
                                                        STAT
                                                    
                                                        Apoptosis
                                                    
                                                        NO Synthase
                                                    
                                                        Nuclear Factor of activated T Cells (NFAT)
                                                    
                                                        Lactate Dehydrogenase
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        SOD
                                                    
                                                        Akt
                                                    
                                                        Caspase
                                                    
                                                        Bcl-2 Family
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    3′,4′,7-Trihydroxyflavone is an orally active inhibitor of OXA-48 (IC50 = 1.89 μM) and COX-1 (IC50 = 36.37 μM). 3′,4′,7-Trihydroxyflavone exhibits antioxidant and anti-inflammatory properties, inhibiting the release of inflammatory cytokines such as IL-6, IL-8, and TNF-α. 3′,4′,7-Trihydroxyflavone inhibits H2O2-induced neuronal apoptosis and ROS accumulation, and exerts anti-neuroinflammatory effects by suppressing the JNK-STAT1 pathway. 3′,4′,7-Trihydroxyflavone exhibits antimicrobial and antibiotic-modifying activities against multidrug-resistant Gram-negative enteric bacteria. 3′,4′,7-Trihydroxyflavone inhibits RANKL-induced osteoclast formation via NFATc1. 3′,4′,7-Trihydroxyflavone activates the CREB-BDNF axis and restores scopolamine (HY-N0296)-induced memory deficits in mice         .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                        
                 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Chemical Structure | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-10394S1
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-I1124
 
                                    - 
                                        
                                            
                                                
                                                    
                                                        
                                                        
                                                            
                                                                
                                                                
                                                                
                                                                    1 Publications Verification 
                                                                
                                                             
                                                        
                                                     
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-d8 is a deuterated form of L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 15N ((S)-Valine- 15N) is the  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S6
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5 ((S)-Valine- 13C5) is the  13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S8
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S4
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-1- 13C ((S)-Valine-1- 13C) is the  13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-B1075AS
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    (Rac)-Fosfomycin (benzylamine)- 13C3 is the  13C labeled Fosfomycin . Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-W016456S
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    5-Bromopentanoic-3,3,4,4 Acid-d4 is the deuterium labeled 5-Bromopentanoic-3,3,4,4 Acid (HY-W016456). 5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S5
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-2- 13C ((S)-Valine-2- 13C) is the  13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S9
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 15N,d8 ((S)-Valine- 15N,d8) is the deuterium and  15N labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S1
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5, 15N ((S)-Valine- 13C5, 15) is the  13C- and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S7
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine-1- 13C, 15N ((S)-Valine-1- 13C, 15N) is the  13C- and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S2
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5, 15N,d8 ((S)-Valine- 13C5, 15N,d8) is the deuterium,  13C-, and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0717S3
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    L-Valine- 13C5, 15N,d2 ((S)-Valine- 13C5, 15N,d2) is the deuterium,  13C-, and  15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                        
                    
                 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                             | 
                            Classification | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-169175
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Alkynes
                                                        
                                                        
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    CN-CC-861 is a broad-spectrum antibiotic. CN-CC-861 shows antibiotic activities for susceptible and multidrug-resistant bacteria. CN-CC-861 shows potent bactericidal activity in vivo .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-174333
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                 | 
                                                
                                                    
                                                        
                                                        
                                                            Alkynes
                                                        
                                                        
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    CYP1A1-IN-1 (Compound 47) is a small-molecule cytochrome P4501A1 (CYP1A1) inhibitor. CYP1A1-IN-1 reduces the bacterial loads of methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii by enhancing macrophage phagocytosis. CYP1A1-IN-1 is promising for research of sepsis caused by multidrug-resistant (MDR) bacteria .
                                                 | 
                                            
                                        
                                     
                                
                             
                        
                        
                    
                 
            
                
                
                    
                        
                            
                                | Cat. No. | 
                                Product Name | 
                                 | 
                                Classification | 
                            
                        
                        
                            
                            
                        - 
                            
                                - HY-N0717
 
                                - 
                                    
                                        
                                            | 
                                                
                                                 (S)-Valine 
                                             | 
                                             | 
                                            
                                                
                                                    
                                                    
                                                        Freeze-drying Protective Agents
                                                    
                                                    
                                                
                                                    
                                                    
                                                        Solubilizing Agents
                                                    
                                                    
                                                
                                             | 
                                        
                                        
                                            | 
                                                
                                                    L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase   .
                                                
                                                
                                             | 
                                        
                                    
                                 
                            
                         
                        
                            
                        - 
                            
                                - HY-Z15868
 
                                - 
                                    
                                        
                                            | 
                                                
                                                
                                             | 
                                             | 
                                            
                                                
                                                    
                                                    
                                                        Nucleoside Analogs
                                                    
                                                    
                                                
                                                    
                                                    
                                                        Cytidine
                                                    
                                                    
                                                
                                             | 
                                        
                                        
                                            | 
                                                
                                                    5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli .
                                                
                                                
                                             | 
                                        
                                    
                                 
                            
                         
                        
                        
                    
                     
                
         
        
        
        
        
        
        
            
            Your information is safe with us.  * Required Fields. 
             
            
         
        
        
            
            
                
                
                Inquiry Information
                
                    - Product Name:
 
                    
                    - Cat. No.:
 
                    
                    - Quantity:
 
                    
                    
                    - MCE Japan Authorized Agent: