2. Anti-infection
  3. Antibiotic Bacterial
  4. Polymyxin B2

Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Polymyxin B2 Chemical Structure

Polymyxin B2 Chemical Structure

CAS No. : 34503-87-2

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Based on 1 publication(s) in Google Scholar

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Polymyxin B2 Related Antibodies

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Description

Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains[1].

Cellular Effect
Cell Line Type Value Description References
Vero CC50
159 μg/mL
Compound: Polymyxin B2
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
[PMID: 29412662]
Molecular Weight

1189.45

Formula

C55H96N16O13
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Polymyxin B2 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polymyxin B234503-87-2Polymyxin B 2Polymyxin B-2AntibioticBacterialGram-negative bacteriaantibioticslipopolysaccharidesdrug-resistant strainsInhibitorinhibitorinhibit

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