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AA

" in MedChemExpress (MCE) Product Catalog:

220

Inhibitors & Agonists

26

Biochemical Assay Reagents

62

Peptides

1

Inhibitory Antibodies

25

Natural
Products

47

Recombinant Proteins

8

Isotope-Labeled Compounds

25

Antibodies

10

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134932

    Ser/Thr Protease Inflammation/Immunology
    AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity .
    AA74-1
  • HY-18544

    MAGL FAAH Metabolic Disease
    AA38-3 is a serine hydrolase (SH) inhibitor. AA38-3 can inhibit three SHs, ABHD6, ABHD11, and FAAH .
    AA38-3
  • HY-18522

    Phospholipase Metabolic Disease
    AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines .
    AA26-9
  • HY-159700

    Liposome Infection
    AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
    AA3-DLin
  • HY-117204

    Antibiotic Infection
    AA-57 is an acidic lipophilic antibiotic isolated from the fermentation broth of Actinomycetes strain AA-57. The AA-57 strain was isolated from a soil sample collected in Koriyama City, Fukushima Prefecture, Japan. AA-57 has antibacterial properties against Gram-positive bacteria, Gram-negative bacteria, and acid-fast bacteria. AA-57 was discovered by screening actinomycete cultures for antibacterial properties. AA-57 exhibits significant antibacterial activity and has inhibitory effects against a variety of bacteria. The discovery of AA-57 provides new possibilities for antibacterial therapy.
    AA-57
  • HY-106300

    Others Cardiovascular Disease
    AA 193 is a uricosuric agent. AA 193 increases urate excretion in hyperuricemic rats .
    AA 193
  • HY-121043A

    Adrenergic Receptor Inflammation/Immunology
    AA 497 is an adrenergic beta-2 agonist. AA 497 is a bronchodilator .
    AA 497
  • HY-106325

    Phosphodiesterase (PDE) Inflammation/Immunology
    AA 2379 is an orally active antirheumatic agent. AA 2379 has antiinflammatory, antipyretic activities and reduces pain sensation .
    AA 2379
  • HY-113755

    Drug Derivative Others
    AA-1777 is an active compound.
    AA-1777
  • HY-121043

    Adrenergic Receptor Inflammation/Immunology
    AA 497 free base is an adrenergic beta-2 agonist. AA 497 free base is a bronchodilator .
    AA 497 free base
  • HY-103522

    GABA Receptor Neurological Disease
    AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases .
    AA29504
  • HY-125958

    Glutaminase Cancer
    AA9 is a potent Transglutaminase 2 (TG2) inhibitor. AA9 strongly impacts HIF-mediated hypoxia in MDA-MB-231 cells .
    AA9
  • HY-12886

    AA 861

    Lipoxygenase Ferroptosis Inflammation/Immunology
    Docebenone (AA 861) is a potent, selective and orally active 5-LO (5-lipoxygenase) inhibitor.
    Docebenone
  • HY-121931

    Lipoxygenase Cancer
    AA863 is a 5-lipoxygenase inhibitor with activity in inhibiting the proliferation of human glioma cells. AA863 exhibits significant and dose-dependent inhibitory effects in monolayer cultured glioma cells with an IC50 of 9.0 micromolar .
    AA863
  • HY-124157

    Others Neurological Disease
    AA41612 is a potent antagonist of melanopsin-mediated phototransduction .
    AA41612
  • HY-P5854

    Potassium Channel Neurological Disease
    Aa1 toxin, a neurotoxic peptide that can be obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker. Aa1 toxin can be used in the study of neurological diseases .
    Aa1 toxin
  • HY-124293
    AA147
    4 Publications Verification

    ATF6 Reactive Oxygen Species (ROS) Neurological Disease Metabolic Disease
    AA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating ATF6 arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection .
    AA147
  • HY-119390

    DNA Methyltransferase Cancer
    AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification .
    AA-CW236
  • HY-125145
    AA92593
    2 Publications Verification

    Others Metabolic Disease Cancer
    AA92593 is a selective and competitive melanopsin OPN4 antagonist .
    AA92593
  • HY-125928

    Sodium Channel Neurological Disease
    AA43279 is an in gamma-aminobutyric acid (GABA) fast-firing interneurons located activator for Nav1.1 channel (SCN1A) with an EC50 of 9.5 μM. AA43279 enhances specific neuronal firing activity in vitro, and exhibits anticonvulsant activity in rat MEST model .
    AA43279
  • HY-157254

    Glutaminase Cancer
    AA10 is a potent and irreversible transglutaminase 2 (TG2) inhibitor for cancer research .
    AA10
  • HY-148859

    Liposome Metabolic Disease Inflammation/Immunology
    AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .
    AA-T3A-C12
  • HY-D1021

    Aminoallyl-dUTP sodium salt

    DNA/RNA Synthesis Others
    AA-dUTP sodium salt is a fluorescent dye which can be used to stain cDNA.
    AA-dUTP sodium salt
  • HY-134351

    Amino Acid Derivatives Metabolic Disease
    AA-dUTP tetrasodium is an amine-modified nucleotide that has been used in the synthesis of fluorescently labeled dUTP.
    AA-dUTP tetrasodium
  • HY-168969

    PROTACs Cancer
    AA-BR-157 is a PROTAC degrader for metallothionein 2A (MT2A) with a DC50 of 190 nM. AA-BR-157 downregulates the cytoskeleton and cell motility regulating protein DIAPH3, inhibits the migration of MDA-MB-231 and U-87 MG. AA-BR-157 regulates the zinc homeostasis in MDA-MB-231 . (Pink: ligand for target protein MT2A ligand 1 (HY-168970); Black: linker (HY-119429); Blue: ligand for VHL E3 ligase (HY-125845))
    AA-BR-157
  • HY-108283

    AA 149; Supacal

    Others Inflammation/Immunology
    Trepibutone (AA 149) increases secretion of bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract. Trepibutone can be used for the research of cholecystitis and functional gastrointestinal disorders .
    Trepibutone
  • HY-134352

    Nucleoside Antimetabolite/Analog Cardiovascular Disease
    AA-UTP tetrasodium is an amine-modified nucleotide that can be directly incorporated into labeled-UTP (HY-107372) .
    AA-UTP tetrasodium
  • HY-B0774
    Seratrodast
    4 Publications Verification

    AA 2414

    Ferroptosis JNK MDM-2/p53 Prostaglandin Receptor Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity .
    Seratrodast
  • HY-N6958
    2-O-β-D-Glucopyranosyl-L-ascorbic acid
    1 Publications Verification

    AA-2βG

    Others Metabolic Disease Cancer
    2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG), isolated from Lycium chinense, is a stable vitamin C analog with anti-tumor activity .
    2-O-β-D-Glucopyranosyl-L-ascorbic acid
  • HY-108283R

    AA 149 (Standard); Supacal (Standard)

    Calcium Channel Reference Standards Inflammation/Immunology
    Trepibutone (Standard) is the analytical standard of Trepibutone. This product is intended for research and analytical applications. Trepibutone (AA 149) increases secretion of bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract. Trepibutone can be used for the research of cholecystitis and functional gastrointestinal disorders .
    Trepibutone (Standard)
  • HY-103337

    Arachidonyl serotonin; AA-5-HT

    FAAH TRP Channel Neurological Disease
    N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents .
    N-Arachidonoylserotonin
  • HY-B0774R

    AA 2414 (Standard)

    Ferroptosis JNK MDM-2/p53 Prostaglandin Receptor Reference Standards Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Seratrodast (Standard) is the analytical standard of Seratrodast. This product is intended for research and analytical applications. Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity .
    Seratrodast (Standard)
  • HY-B0713
    Amlexanox
    Maximum Cited Publications
    17 Publications Verification

    AA673; Amoxanox; CHX3673

    IKK Metabolic Disease
    Amlexanox (AA673; Amoxanox; CHX3673) is a specific inhibitor of IKKε and TBK1, and inhibits the IKKε and TBK1 activity determined by MBP phosphorylation with an IC50 of approximately 1-2 μM.
    Amlexanox
  • HY-B0713R

    AA673 (Standard); Amoxanox (Standard); CHX3673 (Standard)

    Reference Standards IKK Metabolic Disease
    Amlexanox (Standard) is the analytical standard of Amlexanox. This product is intended for research and analytical applications. Amlexanox (AA673; Amoxanox; CHX3673) is a specific inhibitor of IKKε and TBK1, and inhibits the IKKε and TBK1 activity determined by MBP phosphorylation with an IC50 of approximately 1-2 μM.
    Amlexanox (Standard)
  • HY-101518

    APG-115; AA-115

    MDM-2/p53 E1/E2/E3 Enzyme Apoptosis Cancer
    Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively . Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner .
    Alrizomadlin
  • HY-P3103

    DNA/RNA Synthesis Cancer
    PINT-87aa, an 87-amino acid (aa) peptide, is encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT). PINT-87aa directly interacts with polymerase associated factor complex (PAF1c) and inhibits the transcriptional elongation of multiple oncogenes. PINT-87aa suppresses glioblastoma cell proliferation in vitro and in vivo .
    PINT-87aa
  • HY-P3103A

    DNA/RNA Synthesis Cancer
    PINT-87aa TFA, an 87-amino acid (aa) peptide, is encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT). PINT-87aa TFA directly interacts with polymerase associated factor complex (PAF1c) and inhibits the transcriptional elongation of multiple oncogenes. PINT-87aa TFA suppresses glioblastoma cell proliferation in vitro and in vivo .
    PINT-87aa TFA
  • HY-P10552

    CXCR Inflammation/Immunology
    pCXCL8-1aa is an anti-inflammatory peptide. pCXCL8-1aa competitively inhibits the binding of CXCL8 to glycosaminoglycans such as heparin sulfate (HS) by binding with high affinity. This reduces the presentation of CXCL8 on the surface of vascular endothelial cells, thereby inhibiting neutrophil migration and inflammatory responses. pCXCL8-1aa can be used to study inflammatory diseases such as rheumatoid arthritis .
    pCXCL8-1aa
  • HY-158501

    Mannose-5 N-linked oligosaccharide, 2-AA labelled; Oligomannose 5 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    M5 glycan (Man5), 2-AA labelled (Mannose-5 N-linked oligosaccharide, 2-AA labelled; Oligomannose 5 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    M5 glycan (Man5), 2-AA labelled
  • HY-158483

    Mannose-3 N-linked oligosaccharide, 2-AA labelled; Oligomannose 3 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    M3 glycan (Man3), 2-AA labelled (Mannose-3 N-linked oligosaccharide, 2-AA labelled; Oligomannose 3 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    M3 glycan (Man3), 2-AA labelled
  • HY-158511

    Mannose-6 N-linked oligosaccharide, 2-AA labelled; Oligomannose 6 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    M6 glycan (Man6), 2-AA labelled (Mannose-6 N-linked oligosaccharide, 2-AA labelled; Oligomannose 6 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    M6 glycan (Man6), 2-AA labelled
  • HY-158521

    Mannose-7 N-linked oligosaccharide, 2-AA labelled; Oligomannose 7 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    M7 glycan (Man7), 2-AA labelled (Mannose-7 N-linked oligosaccharide, 2-AA labelled; Oligomannose 7 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    M7 glycan (Man7), 2-AA labelled
  • HY-158544

    Mannose-9 N-linked oligosaccharide, 2-AA labelled; Oligomannose 9 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    M9 glycan (Man9), 2-AA labelled (Mannose-9 N-linked oligosaccharide, 2-AA labelled; Oligomannose 9 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    M9 glycan (Man9), 2-AA labelled
  • HY-158536

    Mannose-8 N-linked oligosaccharide, 2-AA labelled; Oligomannose 8 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    M8 glycan (Man8), 2-AA labelled (Mannose-8 N-linked oligosaccharide, 2-AA labelled; Oligomannose 8 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    M8 glycan (Man8), 2-AA labelled
  • HY-154837S

    Isotope-Labeled Compounds Others
    Lu AA39835-d2 is the deuterium labeled Lu AA39835 (HY-154837) .
    Lu AA39835-d3
  • HY-P4051

    HBV Infection Inflammation/Immunology
    HBV Seq1 aa:141-151 is a peptide. HBV Seq1 aa:141-151 can be used for the research of chronic hepatitis B virus (HBV) .
    HBV Seq1 aa:141-151
  • HY-158499

    FA2 N-linked oligosaccharide, 2-AA labelled; F(6)A2 glycan, 2-AA labelled

    Biochemical Assay Reagents Others
    FA2 glycan (G0F), 2-AA labelled (FA2 N-linked oligosaccharide, 2-AA labelled; F(6)A2 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    FA2 glycan (G0F), 2-AA labelled
  • HY-158540

    A4 N-linked oligosaccharide, 2-AA labelled

    Biochemical Assay Reagents Others
    A4 glycan, 2-AA labelled (A4 N-linked oligosaccharide, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    A4 glycan, 2-AA labelled
  • HY-158529

    A3 N-linked oligosaccharide, 2-AA labelled

    Biochemical Assay Reagents Others
    A3 glycan, 2-AA labelled (A3 N-linked oligosaccharide, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    A3 glycan, 2-AA labelled
  • HY-N3027R

    Reference Standards PPAR Metabolic Disease
    Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa. This product is intended for research and analytical applications. Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ) .
    Soyasaponin Aa (Standard)

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