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233

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135416
    Streptolysin O
    1 Publications Verification

    Endogenous Metabolite Infection
    Streptolysin O, a group A streptococcal toxin, is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin. Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state .
    Streptolysin O
  • HY-16566
    Kanamycin
    15+ Cited Publications

    Kanamycin A

    Antibiotic Bacterial Infection Inflammation/Immunology
    Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
    Kanamycin
  • HY-16566A
    Kanamycin sulfate
    15+ Cited Publications

    Kanamycin A sulfate

    Bacterial Antibiotic Infection
    Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
    Kanamycin sulfate
  • HY-135416A

    Endogenous Metabolite Infection
    Streptolysin O (≥1000000 units/mg) is a ≥1000000 units/mg Streptolysin O (HY-135416). Streptolysin O, a group A streptococcal toxin, is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin. Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state .
    Streptolysin O (≥1000000 units/mg)
  • HY-B1418
    Tazobactam
    10+ Cited Publications

    CL-298741; YTR-830H

    Beta-lactamase Antibiotic Bacterial Infection Cancer
    Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .
    Tazobactam
  • HY-13832S

    Isotope-Labeled Compounds Parasite Infection
    Atovaquone-d4 is the deuterium labeled Atovaquone. Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia[1].
    Atovaquone-d4
  • HY-16566R

    Kanamycin A (Standard)

    Reference Standards Antibiotic Bacterial Infection Inflammation/Immunology
    Kanamycin (Standard) is the analytical standard of Kanamycin. This product is intended for research and analytical applications. Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia[1][2][3][4].
    Kanamycin (Standard)
  • HY-16566AR

    Kanamycin A sulfate (Standard)

    Reference Standards Bacterial Antibiotic Infection
    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .
    Kanamycin sulfate (Standard)
  • HY-P10721

    Antibiotic Bacterial Infection
    Plectasin is a peptide antibiotic derived from saprophytic fungi. Plectasin can kill pneumococcus in vitro. Plectasin can alleviate experimental peritonitis and pneumonia caused by pneumococcus in mice .
    Plectasin
  • HY-16908AR

    BC-3781 acetate (Standard)

    Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Lefamulin (acetate) (Standard) is the analytical standard of Lefamulin (acetate). This product is intended for research and analytical applications. Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia[1].
    Lefamulin acetate (Standard)
  • HY-172223

    C3Guo

    SARS-CoV Infection
    3-Deazaguanosine (C3Guo) has potent antiviral activity against SARS-CoV-2 (EC50: 1.14 μM, CC50: >200 μM for Vero E6 cells). 3-Deazaguanosine prevents COVID-19 pneumonia .
    3-Deazaguanosine
  • HY-108971

    Antibiotic Bacterial Infection
    Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections .
    Demecycline
  • HY-P99919

    Interleukin Related Infection
    Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia .
    Efmarodocokin alfa
  • HY-17452

    ME 1206

    Beta-lactamase Bacterial Infection Inflammation/Immunology
    Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
    Cefditoren sodium
  • HY-B1418R

    CL-298741 (Standard); YTR-830H (Standard)

    Beta-lactamase Reference Standards Antibiotic Bacterial Infection
    Tazobactam (Standard) is the analytical standard of Tazobactam. This product is intended for research and analytical applications. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .
    Tazobactam (Standard)
  • HY-19647

    FCE 22891; RIPM-AC; Ritipenem acetoxymethyl ester

    Beta-lactamase Antibiotic Bacterial Infection
    Ritipenem acoxil (FCE 22891; RIPM-AC) is an oral active beta-lactamase antibiotic and can be used for study of bacterial pneumonia .
    Ritipenem acoxil
  • HY-133937

    Bacterial HIV Infection
    Sulfametrole is an orally active and potent antibacterial. Sulfametrole can be used for infections research, such as HIV, severe pneumonia and UTIs (urinary tract infections) .
    Sulfametrole
  • HY-N0802
    Tenuigenin
    2 Publications Verification

    Senegenin

    NF-κB Bacterial Infection Inflammation/Immunology
    Tenuigenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibiting NF-κB activation. Tenuigenin has anti-inflammatory effect .
    Tenuigenin
  • HY-N9977

    Others Inflammation/Immunology
    Dihydrocatalpol can be isolated from Rehmannia glutinosa. Dihydrocatalpol can be used for research on Asthma, chronic obstructive pneumonia, allergic rhinitis .
    Dihydrocatalpol
  • HY-17452A

    Cefditoren pivoxyl; Cefditoren pivaloyloxymethyl ester; ME 1207

    Beta-lactamase Bacterial Antibiotic Infection Inflammation/Immunology
    Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
    Cefditoren Pivoxil
  • HY-17452B

    Cefditoren pivoxyl hydrochloride; Cefditoren pivaloyloxymethyl ester hydrochloride; ME 1207 hydrochloride

    Beta-lactamase Bacterial Antibiotic Infection Inflammation/Immunology
    Cefditoren Pivoxil (ME 1207) hydrochloride is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
    Cefditoren Pivoxil hydrochloride
  • HY-B1190
    Cefadroxil
    2 Publications Verification

    BL-S 578

    Bacterial Antibiotic EAAT Infection Neurological Disease
    Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .
    Cefadroxil
  • HY-B0441
    Tobramycin
    10+ Cited Publications

    Nebramycin Factor 6; Deoxykanamycin B

    Bacterial Antibiotic Infection Cancer
    Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .
    Tobramycin
  • HY-120382

    Bacterial Infection
    LY 215890 ia an orally active antibacterial agent aganist Escherichia coli EC14 and Klebsiella pneumonia X26 .
    LY 215890
  • HY-N0802R

    Senegenin (Standard)

    Reference Standards NF-κB Bacterial Infection Inflammation/Immunology
    Tenuigenin (Standard) is the analytical standard of Tenuigenin. This product is intended for research and analytical applications. Tenuigenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibiting NF-κB activation. Tenuigenin has anti-inflammatory effect .
    Tenuigenin (Standard)
  • HY-B0441R

    Nebramycin Factor 6 (Standard); Deoxykanamycin B (Standard)

    Reference Standards Bacterial Antibiotic Infection Cancer
    Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .
    Tobramycin (Standard)
  • HY-100442S

    ABR-215757-d5; ABR 25757-d5

    SARS-CoV Isotope-Labeled Compounds Metabolic Disease
    Paquinimod-d5 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .
    Paquinimod-d5
  • HY-16908
    Lefamulin
    3 Publications Verification

    BC-3781

    Bacterial Antibiotic Infection
    Lefamulin (BC-3781) is an orally active antibiotic. Lefamulin inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin has anti-inflammatory activity. Lefamulin can be used in the research of bacterial infections, such as bacterial pneumonia .
    Lefamulin
  • HY-16908A
    Lefamulin acetate
    3 Publications Verification

    BC-3781 acetate

    Bacterial Antibiotic Infection Inflammation/Immunology
    Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia .
    Lefamulin acetate
  • HY-100442S1

    ABR-215757-d5-1; ABR 25757-d5-1

    SARS-CoV Isotope-Labeled Compounds Metabolic Disease Inflammation/Immunology
    Paquinimod-d5-1 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .
    Paquinimod-d5-1
  • HY-W740028

    ME 1206-d3

    Isotope-Labeled Compounds Bacterial Beta-lactamase Infection Inflammation/Immunology
    Cefditoren-d3 (sodium) (ME 1206-d3) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
    Cefditoren-d3 sodium
  • HY-17452AR

    Cefditoren pivoxyl (Standard); Cefditoren pivaloyloxymethyl ester (Standard); ME 1207 (Standard)

    Beta-lactamase Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Cefditoren Pivoxil (Standard) is the analytical standard of Cefditoren Pivoxil. This product is intended for research and analytical applications. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
    Cefditoren Pivoxil (Standard)
  • HY-66011
    Moxifloxacin Hydrochloride
    10+ Cited Publications

    BAY 12-8039

    Bacterial Antibiotic Infection Cancer
    Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia .
    Moxifloxacin Hydrochloride
  • HY-P3600

    Apoptosis Inflammation/Immunology
    FIZZ-1 (32-51) (mouse) is a cysteine-rich secretory protein that is highly expressed by macrophages, bronchial epithelial and type II alveolar epithelial cells (AEC) in allergic airway inflammation. FIZZ1 (32-51) (mouse) also shows an antiapoptotic effect on lung fibroblasts. FIZZ-1 (32-51) (mouse) can be used in the study of allergic pneumonia .
    FIZZ-1 (32-51) (mouse)
  • HY-P10559

    Bacterial Infection
    (RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models .
    (RXR)4XB
  • HY-174980

    Bacterial Infection
    KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with IC50 of 0.533  μM and Kiof 0.194  μM. KPC-2-IN-3 has an antimicrobial activity against carbapenem-resistant K. pneumonia K47-25 and reduces bacterial count with a postantibiotic effect in synergy with Meropenem (HY-13678). KPC-2-IN-3 significantly reduces lung bacterial load in a murine pneumonia model .
    KPC-2-IN-3
  • HY-P991501

    SARS-CoV Infection
    Meplazumab is a human IgG2 monoclonal antibody (mAb) targeting Basigin/CD147. Meplazumab can be used in COVID-19 pneumonia, Coronary artery disease and Malaria research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
    Meplazumab
  • HY-P10559A

    Bacterial Infection
    (RXR)4XB TFA is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB TFA-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models .
    (RXR)4XB TFA
  • HY-13832
    Atovaquone
    4 Publications Verification

    Atavaquone

    Parasite Cytochrome P450 Antibiotic Bacterial Infection Cancer
    Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia .
    Atovaquone
  • HY-17452AS

    Cefditoren pivoxyl-d3; Cefditoren pivaloyloxymethyl ester-d3; ME 1207-d3

    Isotope-Labeled Compounds Antibiotic Beta-lactamase Bacterial Infection Inflammation/Immunology
    Cefditoren Pivoxil-d3 (Cefditoren pivoxyl-d3) is deuterium labeled Cefditoren Pivoxil. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
    Cefditoren Pivoxil-d3
  • HY-147240

    ADX-629

    Others Infection Cardiovascular Disease Inflammation/Immunology
    Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes .
    Acloproxalap
  • HY-147878

    Bacterial Infection
    Antibacterial agent 111 (Compound 3) is an antibacterial agent with MIC values of 3.90 μg/mL and 0.49 μg/mL against B. cereus and K. pneumonia, respectively. Antibacterial agent 111 firmly binds with tyrosyl-tRNA synthetase residues .
    Antibacterial agent 111
  • HY-159687

    WCK 4873

    Antibiotic Bacterial Infection
    Nafithromycin (WCK 4873) is an orally available antibiotic that inhibits community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Methicillin (HY-121544)-susceptible Staphylococcus aureus. The MIC90 of nafithromycin against macrolide-resistant and telithromycin (HY-A0062)-insensitive Streptococcus pneumoniae is 0.12 mg/liter .
    Nafithromycin
  • HY-P2454

    Bacterial Infection
    CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent .
    CSP1
  • HY-N13798

    NF-κB Biochemical Assay Reagents Inflammation/Immunology
    ADHPE is a stabilizer of 14-3-3σ and p65 protein complex. ADHPE inhibits NF-κB (p65) signaling pathway and reduces the inflammatory response. ADHPE can be used for pediatric pneumonia-related acute lung injury and acute respiratory distress syndrome study .
    ADHPE
  • HY-13832R

    Atavaquone (Standard)

    Reference Standards Parasite Cytochrome P450 Antibiotic Bacterial Infection Cancer
    Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia .
    Atovaquone (Standard)
  • HY-139554

    KBP-7072

    Antibiotic Bacterial Infection
    Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
    Zifanocycline
  • HY-P3078

    Bacterial Antibiotic Infection
    Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci .
    Amphomycin
  • HY-101726

    Antibiotic Bacterial Infection
    DuP 105 is an orally active oxazolidinone with activity against Gram-positive bacteria. DuP 105 protects staphylococcal and streptococcal infections in mice .
    DuP 105
  • HY-10004

    Faropenem medoxil

    Antibiotic Bacterial Infection
    Faropenem daloxate (Faropenem medoxil) is an orally active beta-lactam antibiotic. Faropenem daloxate has excellent in vitro activity against Streptococcus pneumonia, Haemophilus influenza, and other key pathogens implicated in acute bacterial rhino sinusitis. Faropenem daloxate can be studied in research for respiratory pathogens and acute bacterial sinusitis .
    Faropenem daloxate

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