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Results for "

therapeutic peptides

" in MedChemExpress (MCE) Product Catalog:

269

Inhibitors & Agonists

3

Biochemical Assay Reagents

270

Peptides

27

Natural
Products

2

Isotope-Labeled Compounds

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-42649
    NSC 14699

    		Bacterial Neurological Disease
    NSC 14699 is a small molecule non-peptide inhibitor of botulinum neurotoxin serotype E. NSC 14699 is promising for research of therapeutic and cosmetic agents .
    NSC 14699
  • HY-P5285
    Lunasin

    		Parasite Infection Inflammation/Immunology Cancer
    Lunasin is a bioactive peptide with antioxidant, anti-inflammatory, anticancer and anti-aging properties. Lunasin can be isolated from soybean. Lunasin also has an epigenetic mechanism of action associated with histone acetylation. Lunasin can be internalized into cells and inhibit Oncosphere formation in cancer cells .
    Lunasin
  • HY-147050
    Ahx-DM1

    		Target Protein Ligand-Linker Conjugates Others
    Ahx-DM1 (compound 2A) is a conjugate of protein/peptide which can be combined with a therapeutic, diagnostic or labelling agent .
    Ahx-DM1
  • HY-147050A
    Ahx-DM1 TFA

    		Target Protein Ligand-Linker Conjugates Others
    Ahx-DM1 (TFA) (compound 2A) is a conjugate of protein/peptide which can be combined with a therapeutic, diagnostic or labelling agent .
    Ahx-DM1 TFA
  • HY-W440900
    DSPE-PEG-SPDP (MW 3400)

    		Biochemical Assay Reagents Others
    DSPE-PEG-SPDP, MW 3400 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents, such as hydrophilic nutrierns (protein/peptide, mRNA/DNA/siRNA) or hdyrophobic drugs ( Reagent grade, for research use only.
    DSPE-PEG-SPDP (MW 3400)
  • HY-P3728
    Interleukin II (60-70)

    		Interleukin Related Inflammation/Immunology
    Interleukin II (60-70) is a 60-70 fragment of the cytokine Interleukin II polypeptide .
    Interleukin II (60-70)
  • HY-P10649
    CPP12

    		Fluorescent Dye Cancer
    CPP12 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP12 can be used for intracellular delivery of therapeutic agents and chemical probes .
    CPP12
  • HY-P10644
    CPP9

    		Fluorescent Dye Cancer
    CPP9 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 can be used for intracellular delivery of therapeutic agents and chemical probes .
    CPP9
  • HY-W440898
    DSPE-PEG-SH (MW 5000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-SH, MW 5000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research use only.
    DSPE-PEG-SH (MW 5000)
  • HY-153934
    Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid

    		GHR Endocrinology
    Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid (Ligand 1) improves the pharmacokinetic properties of therapeutic peptides and proteins through non-covalent binding with human serum albumin (HSA). Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid can be used for synthesis of long-acting human growth hormone (HGH) analog somapacitan .
    Tetrazole-C15-(N-acetylsulfamoyl)butanoic acid
  • HY-17012
    Dapitant

    RPR 100893

    		 Neurokinin Receptor Inflammation/Immunology
    Dapitant (RPR 100893) is a non-peptide Substance P antagonist with high affinity for the human NK1 receptor. It belongs to the 7,7,4-trimethylperhydroisoindole class of compounds. Dapitant inhibits the binding of Substance P to NK1 receptors, thereby blocking its neurokinin-mediated effects. This novel antagonist represents a potential therapeutic option for conditions involving Substance P, such as neurogenic inflammation and pain modulation .
    Dapitant
  • HY-W440901
    DSPE-PEG-SPDP (MW 5000)

    		Liposome Others
    DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
    DSPE-PEG-SPDP (MW 5000)
  • HY-14743B
    Golotimod hydrochloride

    SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophan hydrochloride

    		 Bacterial STAT Infection Inflammation/Immunology Cancer
    Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
    Golotimod hydrochloride
  • HY-14743
    Golotimod

    SCV 07; Gamma-D-glutamyl-L-tryptophan

    		 Bacterial STAT Infection Inflammation/Immunology Cancer
    Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
    Golotimod
  • HY-14743A
    Golotimod TFA

    SCV 07 TFA; Gamma-D-glutamyl-L-tryptophan TFA

    		 Bacterial STAT Infection Inflammation/Immunology Cancer
    Golotimod TFA (SCV 07 TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod TFA (SCV 07 TFA) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod TFA (SCV 07 TFA) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
    Golotimod TFA
  • HY-14743R
    Golotimod (Standard)

    		Bacterial STAT Infection Inflammation/Immunology Cancer
    Golotimod (Standard) is the analytical standard of Golotimod. This product is intended for research and analytical applications. Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .
    Golotimod (Standard)
  • HY-P3612
    CTCE-0214

    		CXCR Inflammation/Immunology
    CTCE-0214 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research .
    CTCE-0214
  • HY-106288
    Human PTHrP-(1-36)

    		PTHR Cancer
    Human PTHrP-(1-36) is a secretory form of PTHrP with anticalciuric effects. Human PTHrP-(1-36) enhances beta cell function and proliferation. Human PTHrP-(1-36) can be used in the research of humoral hypercalcemia of malignancy (HHM) and hyperparathyroidism .
    Human PTHrP-(1-36)
  • HY-P1651
    SOR-C13

    		TRP Channel Cancer
    SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity .
    SOR-C13
  • HY-P0264
    Exendin(9-39) amide
    25+ Cited Publications

    Avexitide

    		 GLP Receptor Metabolic Disease
    Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH) .
    Exendin(9-39) amide
  • HY-P2141
    TRV-120027
    3 Publications Verification

    TRV027

    		 Angiotensin Receptor Arrestin Cardiovascular Disease
    TRV120027, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling . TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R-β-arrestin-1-TRPC3-PLCγ at the plasma membrane. TRV120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment .
    TRV-120027
  • HY-P0049
    Argipressin
    5+ Cited Publications

    Arg8-vasopressin; AVP

    		 Vasopressin Receptor Neurological Disease Cancer
    Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
    Argipressin
  • HY-P1975
    Aureobasidin A
    2 Publications Verification

    Basifungin

    		 Antibiotic Fungal Parasite Infection Inflammation/Immunology
    Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity .
    Aureobasidin A
  • HY-P2076
    Dusquetide

    SGX942

    		 p62 Bacterial Infection Cancer
    Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection . DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns
    Dusquetide
  • HY-A0162R
    Quinupristin (Standard)

    		Antibiotic Reference Standards Bacterial Infection
    Bictegravir (sodium) (Standard) is the analytical standard of Bictegravir (sodium). This product is intended for research and analytical applications. Bictegravir sodium is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity .
    Quinupristin (Standard)
  • HY-P3624
    Cenderitide

    		Guanylate Cyclase Cardiovascular Disease
    Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research .
    Cenderitide
  • HY-P3042
    Chymostatin

    		SARS-CoV Virus Protease NF-κB Interleukin Related Inflammation/Immunology
    Chymostatin is a SARS-CoV-2 M pro inhibitor. Chymostatin up-regulates endocan and inhibits NF-κBp65 activity. Chymostatin reduces proinflammatory cytokines (IL-1β and IL-6) and HMGB1. Chymostatin shows protective effects against Paraquat-induced acute lung injury. Chymostatin exhibits anticancer activity against lung cancer .
    Chymostatin
  • HY-13534
    Abarelix
    1 Publications Verification

    R3827; PPI 149

    		 GnRH Receptor Endocrinology Cancer
    Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment.
    Abarelix
  • HY-D0844
    Glutathione oxidized
    5+ Cited Publications

    L-Glutathione oxidized; GSSG; Oxiglutatione

    		 Endogenous Metabolite Reactive Oxygen Species (ROS) Metabolic Disease
    Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .
    Glutathione oxidized
  • HY-P1333
    Dynorphin A

    		Opioid Receptor Apoptosis Caspase Endogenous Metabolite Neurological Disease
    Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease .
    Dynorphin A
  • HY-120880
    SKF107457

    		HIV Protease Infection
    SKF107457 is an HIV-1 protease inhibitor that can be used in AIDS research .
    SKF107457
  • HY-P4062
    Insulin peglispro

    BIL

    		 Insulin Receptor Metabolic Disease
    Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins .
    Insulin peglispro
  • HY-P0093
    Sincalide
    3 Publications Verification

    Cholecystokinin octapeptide; CCK-8; SQ19844

    		 Cholecystokinin Receptor Apoptosis PI3K Akt Infection Cancer
    Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .
    Sincalide
  • HY-109538
    Secretin (swine)

    		Secretin Receptor Neurological Disease Metabolic Disease
    Secretin (swine), a neuroendocrine hormone, is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which acts on secretin receptors. Secretin is expressed by cells in all mature enteroendocrine cell subsets and can be prompted by fatty acids. Secretin stimulates the secretion of pancreatic water and bicarbonate. Secretin exerts various effects in organs, can be used for the research of digestive system, central nervous system and energy metabolism .
    Secretin (swine)
  • HY-P3512
    Iseganan

    IB-367

    		 Bacterial Fungal Parasite Infection Cancer
    Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research .
    Iseganan
  • HY-P11270
    Relsipatide

    BG128

    		 Insulin Receptor GLP Receptor Metabolic Disease
    Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
    Relsipatide
  • HY-P10318
    SHR-2042

    		GLP Receptor Endocrinology
    SHR-2042 is a selective agonist of the GLP-1 receptor.SHR-2042 improves glycemic control by activating the GLP-1 receptor, enhancing insulin secretion and inhibiting glucagon secretion. SHR-2042 combined with sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) promotes monomerization through the formation of micelles and improves oral absorption efficiency .
    SHR-2042
  • HY-105037
    Forigerimod

    IPP-201101

    		 Autophagy Inflammation/Immunology
    Forigerimod (IPP-201101) is a CD4 T-cell modulator. Forigerimod is a 21-amino-acid fragment of U1 small nuclear ribonucleoprotein 70 kDa that is phosphorylated at Ser140. Forigerimod can potently inhibit autophagy. Forigerimod can be used for the research of autoimmune disorders, such as systemic lupus erythematosus (SLE) .
    Forigerimod
  • HY-105239
    Selepressin

    FE 202158

    		 Vasopressin Receptor Cardiovascular Disease
    Selepressin (FE 202158) is a selective vasopressin V1A receptor agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock .
    Selepressin
  • HY-P1145
    Glucagon-like peptide 1 (1-37), human
    1 Publications Verification

    HuGLP-1

    		 GCGR Metabolic Disease
    Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.
    Glucagon-like peptide 1 (1-37), human
  • HY-125486
    Reversin 121

    		P-glycoprotein Cancer
    Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-glycoprotein-mediated multidrug resistance. Reversin 121 can be used in the research of cancers .
    Reversin 121
  • HY-P3609
    CR 665

    JNJ 38488502; FE 200665

    		 Opioid Receptor Neurological Disease
    CR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM. CR 665 can be used for the research of peripheral pain .
    CR 665
  • HY-148209
    Balhimycin

    		Antibiotic Bacterial Infection
    Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes .
    Balhimycin
  • HY-17572R
    Atosiban (Standard)

    RW22164 (Standard); RWJ22164 (Standard)

    		 Reference Standards Oxytocin Receptor Vasopressin Receptor Endocrinology Cancer
    Atosiban (Standard) is the analytical standard of Atosiban. This product is intended for research and analytical applications. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .
    Atosiban (Standard)
  • HY-P10305
    Visepegenatide

    PB-119

    		 Insulin Receptor Metabolic Disease
    PB-119 is a PEGylated Exenatide. PB-119 decreases glycemic levels by improving beta-cell function and insulin resistance. PB-119 can be used for research of type 2 diabetes .
    Visepegenatide
  • HY-P0108
    Angiotensin II 5-valine

    Valine angiotensin II; 5-L-Valine angiotensin II

    		 Angiotensin Receptor Endocrinology Cancer
    Angiotensin II 5-valine is an agonist of angiotensin receptor.
    Angiotensin II 5-valine
  • HY-P11274
    Zenagamtide

    Amycretin; NN 9487

    		 GCGR Amylin Receptor Metabolic Disease
    Zenagamtide is a glucagon-like peptide (GLP-1) and amylin receptors agonist .
    Zenagamtide
  • HY-P0004R
    Lysipressin (Standard)

    Lysine vasopressin (Standard); [Lys8]-Vasopressin (Standard)

    		 Reference Standards Adenylate Cyclase Others
    Lysipressin (Standard) is the analytical standard of Lysipressin. This product is intended for research and analytical applications. Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase .
    Lysipressin (Standard)
  • HY-P11271
    Ribupatide

    		Insulin Receptor GLP Receptor Metabolic Disease
    Ribupatide is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
    Ribupatide
  • HY-13443
    Exendin-4
    55+ Cited Publications

    Exenatide

    		 GCGR Cardiovascular Disease Metabolic Disease Cancer
    Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.
    Exendin-4

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