1. Search Result
Search Result
Results for "

SPAAC

" in MedChemExpress (MCE) Product Catalog:

1225

Inhibitors & Agonists

107

Fluorescent Dye

99

Biochemical Assay Reagents

10

Peptides

2

Natural
Products

6

Isotope-Labeled Compounds

1081

Click Chemistry

78

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130809
    DBCO-PEG4-Biotin
    1 Publications Verification

    Biochemical Assay Reagents Cancer
    DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-Biotin
  • HY-155788

    Biochemical Assay Reagents Others
    DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research .
    DSPE-PEG-DBCO ammonium
  • HY-W096149

    Biochemical Assay Reagents Others
    exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    exo-BCN-NHS carbonate
  • HY-W123019

    Biochemical Assay Reagents Others
    DBCO-Sulfo-Link-biotin TEA is a click chemistry intermediate containing a DBCO group, which can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group.
    DBCO-Sulfo-Link-biotin TEA
  • HY-W754588

    PROTAC Linkers Others
    exo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo-BCN-L-Lysine
  • HY-157054

    Biochemical Assay Reagents Others
    Endo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. Endo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-L-Lysine
  • HY-140277

    PROTAC Linkers Cancer
    DBCO-PEG2-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG2-PFP ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG2-PFP ester
  • HY-157182

    Biochemical Assay Reagents Cancer
    DNP-PEG2-NHCO-C2-DBCO is a clickable hapten that bears a dinitrophenyl (DNP) moiety as the antibody‐recruiting motif at one end, a polyethylene glycol chain as a spacer and a dibenzocyclooctene at the other end for the SPAAC chemistry .
    DNP-PEG2-NHCO-C2-DBCO
  • HY-174289

    Biochemical Assay Reagents Others
    TMTHSI succinimide NHS ester is a highly efficient cyclic alkyne click reagent. TMTHSI succinimide NHS ester has the primary activity to rapidly undergo strain-promoted cycloaddition reactions with azides. TMTHSI succinimide NHS ester is easily functionalized and can be linked to a variety of small molecules and (peptides, nucleic acids) biologics via a variety of linkers .
    TMTHSI succinimide NHS ester
  • HY-151754

    ADC Linker Others
    DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity . DACN(Tos2,6-OH) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DACN(Tos2,6-OH)
  • HY-157052

    PROTAC Linkers Others
    exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo-BCN-Fmoc-L-Lysine
  • HY-47018

    ADC Linker Others
    PL1601 is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC) . PL1601 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    PL1601
  • HY-123916

    PROTAC Linkers Cancer
    DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Biotin
  • HY-141293

    PROTAC Linkers Cancer
    Oleic-DBCO is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Oleic-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Oleic-DBCO
  • HY-W000423

    ADC Linker Cancer
    DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-amine
  • HY-174963C

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 2000) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 2000) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 2000)
  • HY-133009

    PROTAC Linkers Cancer
    BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. BCN-PEG4-acid contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-acid
  • HY-174963

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 400) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 400) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 400)
  • HY-174963D

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 3400) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 3400) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 3400)
  • HY-116270

    ADC Linker Cancer
    DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Maleimide
  • HY-126851

    ADC Linker Cancer
    Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Fluorescein-DBCO
  • HY-174963E

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 5000) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 5000) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 5000)
  • HY-174963A

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 600) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 600) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 600)
  • HY-42973
    DBCO-NHS ester
    5+ Cited Publications

    ADC Linker Cancer
    DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-NHS ester
  • HY-174963H

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 10000) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 10000) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 10000)
  • HY-174963B

    Biochemical Assay Reagents Others
    DBCO-PEG-OH (MW 1000) is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG-OH (MW 1000) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG-OH (MW 1000)
  • HY-D2112

    Fluorescent Dye Others
    TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    TAMRA-PEG7-N3
  • HY-D2111

    Fluorescent Dye Others
    TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    TAMRA-PEG2-N3
  • HY-140306

    ADC Linker Cancer
    Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-Sulfo-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Mal-Sulfo-DBCO
  • HY-140293

    PROTAC Linkers Cancer
    DBCO-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-NH-Boc
  • HY-127056

    PROTAC Linkers Cancer
    Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Sulfo DBCO-amine
  • HY-135973

    ADC Linker Cancer
    BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-SS-NHS
  • HY-123687

    ADC Linker Cancer
    DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Sulfo-NHS ester sodium
  • HY-138506

    ADC Linker Cancer
    DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-S-S-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-S-S-acid
  • HY-D2240

    Fluorescent Dye Others
    Sulfo-Cy3.5-DBCO is a fluorescent dye. Sulfo-Cy3.5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Sulfo-Cy3.5-DBCO
  • HY-135977

    ADC Linker Cancer
    DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-aldehyde is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-SS-aldehyde
  • HY-W714234

    Biochemical Assay Reagents Others
    Endo-BCN CE-phosphoramidite is a stable and one of the most reactive cyclooctynes for copper-free click chemistry. Unlike dibenzocyclooctyne (DBCO), BCN is reactive both to azides (strain-promoted azyde-alkyne cycloaddition, SPAAC) and tetrazines (inverse electron demand Diels-Alder reaction, IEDDA).
    Endo-BCN CE-phosphoramidite
  • HY-140280

    PROTAC Linkers Cancer
    DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG1
  • HY-153370

    ADC Linker Cancer
    DBCO-PEG3-oxyamine-Boc hydrochloride is an ADC linker . DBCO-PEG3-oxyamine-Boc (hydrochloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG3-oxyamine-Boc hydrochloride
  • HY-130935

    ADC Linker Cancer
    DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Val-Cit-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Val-Cit-OH
  • HY-133406

    PROTAC Linkers Cancer
    exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    exo BCN-O-PNB
  • HY-174965H

    DBCO-PEG-Thiol (MW 10000)

    Biochemical Assay Reagents Others
    DBCO-PEG-SH (MW 10000) (DBCO-PEG-Thiol (MW 10000)) is a DBCO-modified PEG derivative. DBCO-PEG-SH (MW 10000) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    DBCO-PEG-SH (MW 10000)
  • HY-174965E

    DBCO-PEG-Thiol (MW 5000)

    Biochemical Assay Reagents Others
    DBCO-PEG-SH (MW 5000) (DBCO-PEG-Thiol (MW 5000)) is a DBCO-modified PEG derivative. DBCO-PEG-SH (MW 5000) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    DBCO-PEG-SH (MW 5000)
  • HY-174965D

    DBCO-PEG-Thiol (MW 3400)

    Biochemical Assay Reagents Others
    DBCO-PEG-SH (MW 3400) (DBCO-PEG-Thiol (MW 3400)) is a DBCO-modified PEG derivative. DBCO-PEG-SH (MW 3400) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    DBCO-PEG-SH (MW 3400)
  • HY-174934

    Biochemical Assay Reagents Others
    TCO-PEG-DBCO (MW 3400) is a PEG derivative consisting of DBCO, PEG units, and trans-cyclooctene (TCO). TCO-PEG-DBCO (MW 3400) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    TCO-PEG-DBCO (MW 3400)
  • HY-174965C

    DBCO-PEG-Thiol (MW 2000)

    Biochemical Assay Reagents Others
    DBCO-PEG-SH (MW 2000) (DBCO-PEG-Thiol (MW 2000)) is a DBCO-modified PEG derivative. DBCO-PEG-SH (MW 2000) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    DBCO-PEG-SH (MW 2000)
  • HY-174965

    DBCO-PEG-Thiol (MW 400)

    Biochemical Assay Reagents Others
    DBCO-PEG-SH (MW 400) (DBCO-PEG-Thiol (MW 400)) is a DBCO-modified PEG derivative. DBCO-PEG-SH (MW 400) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    DBCO-PEG-SH (MW 400)
  • HY-130810

    ADC Linker Cancer
    DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Sulfo-Link-biotin
  • HY-174965B

    DBCO-PEG-Thiol (MW 1000)

    Biochemical Assay Reagents Others
    DBCO-PEG-SH (MW 1000) (DBCO-PEG-Thiol (MW 1000)) is a DBCO-modified PEG derivative. DBCO-PEG-SH (MW 1000) contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
    DBCO-PEG-SH (MW 1000)
  • HY-43581

    PROTAC Linkers Cancer
    endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    endo-BCN-O-PNB

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: