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Results for "

EBP

" in MedChemExpress (MCE) Product Catalog:

69

Inhibitors & Agonists

2

Peptides

15

Natural
Products

11

Recombinant Proteins

6

Isotope-Labeled Compounds

24

Antibodies

16

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162351

    Emopamil Binding Protein Metabolic Disease
    EBP-IN-1 (compound 11) is an inhibitor of emopamil-binding protein (EBP), a sterol isomerase in the cholesterol biosynthetic pathway. EBP-IN-1 has a long half-life in rodents and has good metabolic turnover and brain penetration properties. EBP-IN-1 enhances oligodendrocyte formation in human cortical organoids .
    EBP-IN-1
  • HY-10237
    Boceprevir
    30+ Cited Publications

    EBP 520; SCH 503034

    HCV Protease HCV SARS-CoV Infection
    Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay . Boceprevir inhibits SARS-CoV-2 3CL pro activity .
    Boceprevir
  • HY-10466
    Daclatasvir
    Maximum Cited Publications
    47 Publications Verification

    BMS-790052; EBP 883

    HCV Infection
    Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively .
    Daclatasvir
  • HY-10465
    Daclatasvir dihydrochloride
    Maximum Cited Publications
    47 Publications Verification

    BMS-790052 dihydrochloride; EBP 883 dihydrochloride

    HCV Infection
    Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
    Daclatasvir dihydrochloride
  • HY-157482

    Bacterial Infection
    EBP-59 is a bacterial inhibitor with antibiofilm activity against Gram-positive bacteria. EBP-59 is effective against Staphylococcus aureus and MRSA (methicillin–resistant staphylococcus aureus). EBP-59 can be used to study bacterial infections .
    EBP-59
  • HY-RS25383

    Small Interfering RNA (siRNA) Others

    Ebp Rat Pre-designed siRNA Set A contains three designed siRNAs for Ebp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ebp Rat Pre-designed siRNA Set A
    Ebp Rat Pre-designed siRNA Set A
  • HY-RS04130

    Small Interfering RNA (siRNA) Others

    EBP Human Pre-designed siRNA Set A contains three designed siRNAs for EBP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EBP Human Pre-designed siRNA Set A
    EBP Human Pre-designed siRNA Set A
  • HY-RS18892

    Small Interfering RNA (siRNA) Others

    Ebp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ebp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ebp Mouse Pre-designed siRNA Set A
    Ebp Mouse Pre-designed siRNA Set A
  • HY-10237R

    EBP 520 (Standard); SCH 503034 (Standard)

    Reference Standards HCV Protease HCV SARS-CoV Infection
    Boceprevir (Standard) is the analytical standard of Boceprevir. This product is intended for research and analytical applications. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay . Boceprevir inhibits SARS-CoV-2 3CL pro activity .
    Boceprevir (Standard)
  • HY-10237S

    EBP 520-d9; SCH 503034-d9

    Isotope-Labeled Compounds HCV Protease HCV SARS-CoV Infection
    Boceprevir-d9 is the deuterium labeled Boceprevir. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay . Boceprevir inhibits SARS-CoV-2 3CLpro activity .
    Boceprevir-d9
  • HY-10465R

    BMS-790052 dihydrochloride (Standard); EBP 883 dihydrochloride (Standard)

    Reference Standards HCV Infection
    Daclatasvir (dihydrochloride) (Standard) is the analytical standard of Daclatasvir (dihydrochloride). This product is intended for research and analytical applications. Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively .
    Daclatasvir dihydrochloride (Standard)
  • HY-10466R

    BMS-790052 (Standard); EBP 883 (Standard)

    Reference Standards HCV Infection
    Daclatasvir (Standard) is the analytical standard of Daclatasvir. This product is intended for research and analytical applications. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively .
    Daclatasvir (Standard)
  • HY-10062

    EBP-921

    Akt Farnesyl Transferase Cancer
    AZD3409 is a prenyl inhibitor that exhibits inhibitory activity against both farnesyl transferase and geranylgeranyl transferase I. AZD3409 inhibits the growth of breast cancer cells, with IC50s of 220 nM (MDA-MB-468), 180 nM (MDA-MB-361), and 290 nM (SK-Br-3). AZD3409 significantly reduces the activation level of AKT in breast cancer cell lines. AZD3409 induces G0/G1 phase arrest in MDA-MB-468 cells, causes G2/M phase arrest in MDA-MB-361 cells. AZD3409 can be used for the study of breast cancer .
    AZD3409
  • HY-10466BS

    BMS-790052-d6 hydrochloride; EBP 883-d6 hydrochloride

    Isotope-Labeled Compounds Others
    Daclatasvir-d6 hydrochloride is deuterated labeled Daclatasvir.
    Daclatasvir-d6 hydrochloride
  • HY-10466S

    BMS-790052-d6; EBP 883-d6

    Isotope-Labeled Compounds HCV Infection
    Daclatasvir-d6 is deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
    Daclatasvir-d6
  • HY-10466S2

    BMS-790052-d16; EBP 883-d16

    Isotope-Labeled Compounds HCV Infection
    Daclatasvir-d16 is deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
    Daclatasvir-d16
  • HY-10466S1

    BMS-790052-13C2,d6; EBP 883-13C2,d6

    Isotope-Labeled Compounds HCV Infection
    Daclatasvir- 13C2,d6 (BMS-790052- 13C2,d6) is 13C and deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
    Daclatasvir-13C2,d6
  • HY-RS27175

    Small Interfering RNA (siRNA) Others
    Eif4ebp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Eif4ebp2 Rat Pre-designed siRNA Set A
    Eif4ebp2 Rat Pre-designed siRNA Set A
  • HY-RS04279

    Small Interfering RNA (siRNA) Others

    EIF4EBP3 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EIF4EBP3 Human Pre-designed siRNA Set A
    EIF4EBP3 Human Pre-designed siRNA Set A
  • HY-RS26734

    Small Interfering RNA (siRNA) Others

    Eif4ebp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eif4ebp1 Rat Pre-designed siRNA Set A
    Eif4ebp1 Rat Pre-designed siRNA Set A
  • HY-RS04278

    Small Interfering RNA (siRNA) Others

    EIF4EBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EIF4EBP2 Human Pre-designed siRNA Set A
    EIF4EBP2 Human Pre-designed siRNA Set A
  • HY-RS20664

    Small Interfering RNA (siRNA) Others

    Eif4ebp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eif4ebp2 Mouse Pre-designed siRNA Set A
    Eif4ebp2 Mouse Pre-designed siRNA Set A
  • HY-RS20227

    Small Interfering RNA (siRNA) Others

    Eif4ebp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eif4ebp1 Mouse Pre-designed siRNA Set A
    Eif4ebp1 Mouse Pre-designed siRNA Set A
  • HY-RS04277

    Small Interfering RNA (siRNA) Others

    EIF4EBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EIF4EBP1 Human Pre-designed siRNA Set A
    EIF4EBP1 Human Pre-designed siRNA Set A
  • HY-134334

    DNA/RNA Synthesis Inflammation/Immunology
    C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation .
    C/EBPα inducer 1
  • HY-164561

    APC Cancer
    TASIN-30 is an EBP inhibitor, with EC50 values of 0.097 μM for EBP competition and 50 μM for DHCR7 competition, respectively .
    TASIN-30
  • HY-134333

    Apoptosis Cancer
    ICCB280 is a potent inducer of C/EBPα. ICCB280 exhibits anti-leukemic properties including terminal differentiation, proliferation arrest, and apoptosis through activation of C/EBPα and affecting its downstream targets (such as C/EBPε, G-CSFR and c-Myc) .
    ICCB280
  • HY-143510

    mTOR Cancer
    RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.
    RMC-4627
  • HY-RS05464

    Small Interfering RNA (siRNA) Others

    GLB1 Human Pre-designed siRNA Set A contains three designed siRNAs for GLB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GLB1 Human Pre-designed siRNA Set A
    GLB1 Human Pre-designed siRNA Set A
  • HY-114519
    Helenalin acetate
    2 Publications Verification

    Histone Demethylase NF-κB Inflammation/Immunology Cancer
    Helenalin acetate, a natural NF-κB inhibitor, is a potent C/EBPβ inhibitor. Helenalin acetate has anti-inflammatory and anticancer activities .
    Helenalin acetate
  • HY-130723

    AMPK Cancer
    AMPK activator 2 (compound 7a), a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) .
    AMPK activator 2
  • HY-130723A

    AMPK Cancer
    AMPK activator 2 (compound 7a) hydrochloride, a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 hydrochloride inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549) .
    AMPK activator 2 hydrochloride
  • HY-132607

    CEBPA-51

    MicroRNA Inflammation/Immunology Cancer
    MTL-CEPBA is a small activating RNA targeting for upregulation of C/EBPα. MTL-CEPBA has anti-inflammatory and anti-cancer activity .
    MTL-CEBPA
  • HY-115869

    mTOR Cancer
    RMC-4529 has an IC50 value of 1.0 nM against p-4E-BP1-(T37/46) in mTOR kinase cellular assay.
    RMC-4529
  • HY-132607A

    CEBPA-51 sodium

    MicroRNA Inflammation/Immunology Cancer
    MTL-CEBPA (sodium) is the sodium form of MTL-CEBPA (HY-132607). MTL-CEBPA (sodium) is a small activating RNA targeting for upregulation of C/EBPα. MTL-CEBPA (sodium) has anti-inflammatory and anti-cancer activity .
    MTL-CEBPA sodium
  • HY-W011269

    EPA sodium; Timnodonic acid sodium

    Endogenous Metabolite Histone Demethylase Cardiovascular Disease Metabolic Disease Cancer
    Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .
    Eicosapentaenoic Acid sodium
  • HY-B0660
    Eicosapentaenoic Acid
    20+ Cited Publications

    EPA; Timnodonic acid

    Endogenous Metabolite Histone Demethylase Neurological Disease Cancer
    Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
    Eicosapentaenoic Acid
  • HY-B0660A

    EPA (metformin); Timnodonic acid (metformin)

    Endogenous Metabolite Histone Demethylase Neurological Disease Cancer
    Eicosapentaenoic Acid (EPA) metformin is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic acid metformin exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). EEicosapentaenoic acid metformin activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic acid metformin can promote relaxation of vascular smooth muscle cells and vasodilation .
    Eicosapentaenoic acid (metformin)
  • HY-RS12834

    Small Interfering RNA (siRNA) Others

    SH3D19 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3D19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SH3D19 Human Pre-designed siRNA Set A
    SH3D19 Human Pre-designed siRNA Set A
  • HY-P6183

    MMP Cancer
    LXJ-02 is a potent inhibitor of EDPs/EBP peptide–protein interaction, with the KD of 117 μM for EDPs. LXJ-02 activates the macrophage-MMP-12 axis to increase MMP-12 expression and degrade ECM components like elastin .
    LXJ-02
  • HY-B0660R

    EPA (Standard); Timnodonic acid (Standard)

    Reference Standards Endogenous Metabolite Histone Demethylase Neurological Disease Cancer
    Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
    Eicosapentaenoic Acid (Standard)
  • HY-114267

    mTOR Others
    Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).
    Cbz-B3A
  • HY-169751

    Fungal AP-1 Infection Inflammation/Immunology Cancer
    Dihydro-N-caffeoyltyramine is a new phenolic amide that can be isolated from the root bark of wolfberry and has strong antioxidant activity and antifungal effects. Dihydro-N-caffeoyltyramine downregulates the expression of cyclooxygenase-2 by inhibiting the activity of C/EBP and AP-1 transcription factors .
    Dihydro-N-caffeoyltyramine
  • HY-111370

    mTOR Cancer
    mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates .
    mTOR inhibitor-2
  • HY-149292

    Casein Kinase Cancer
    SR-4133 is a potent and highly CK1ε selective inhibitor with an IC50 of 58 nM. SR-4133 binds to the ATP-binding site of CK1ε. SR-4133 displays nanomolar growth inhibition of bladder cancer cells, and inhibits the phosphorylation of 4E-BP1 .
    SR-4133
  • HY-B0660S1

    EPA 1,2,3,4,5-13C, FA 20:5-13C5

    Isotope-Labeled Compounds Endogenous Metabolite Histone Demethylase Neurological Disease Cancer
    Eicosapentaenoic acid 1,2,3,4,5- 13C5 (EPA 1,2,3,4,5- 13C, FA 20:5- 13C5) is 13C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
    Eicosapentaenoic acid 1,2,3,4,5-13C5
  • HY-110188
    BiP inducer X
    5+ Cited Publications

    Apoptosis Neurological Disease
    BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress .
    BiP inducer X
  • HY-N4103
    Fucosterol
    2 Publications Verification

    PARP Endogenous Metabolite Metabolic Disease Cancer
    Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .
    Fucosterol
  • HY-P5275

    CG-Lipoxyn

    NF-κB Histone Demethylase Metabolic Disease
    Tripeptide-41 (CG-Lipoxyn) is a signal peptide. Tripeptide-41 activates the NF-kB signaling pathway, inhibits the expression of C/EBP and increases cAMP. Tripeptide-41 is an important intracellular signaling factor that causes lipolysis by promoting the hydrolysis of lipids into triglycerides. Tripeptide-41 can be used in cosmetics that targets fat accumulation .
    Tripeptide-41
  • HY-N7661

    PPAR Metabolic Disease
    4β-Hydroxywithanolide E, isolated from Physalis peruviana L., inhibits adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion. 4β-Hydroxywithanolide E is an adipogenesis inhibitor and inhibits PPARγ, C/EBPα, and the adipocyte-specific molecule aP2 mRNA expression .
    4β-Hydroxywithanolide E

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