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  5. EBP1 Antibody (YA2509)

EBP1 Antibody (YA2509)

Cat. No.: HY-P82764
User Guide for Antibodies Technical Support

EBP1 Antibody (YA2509) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2509), targeting EBP1, with a predicted molecular weight of 44 kDa (observed band size: 48 kDa). EBP1 Antibody (YA2509) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

EBP1 Antibody (YA2509) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2509), targeting EBP1, with a predicted molecular weight of 44 kDa (observed band size: 48 kDa). EBP1 Antibody (YA2509) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.
Background

The EBP1 protein is implicated in playing a role in an ERBB3-regulated signal transduction pathway and is associated with growth regulation. It acts as a corepressor of the androgen receptor (AR) and is modulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Furthermore, EBP1 inhibits transcription of some E2F1-regulated promoters, potentially by recruiting histone acetylase (HAT) activity. It exhibits RNA-binding capabilities and associates with various mature and precursor rRNAs, suggesting involvement in the regulation of intermediate and late steps of rRNA processing and ribosome assembly. Additionally, EBP1 mediates cap-independent translation of specific viral internal ribosomal entry sites (IRESs). Functionally, it plays a role in regulating cell proliferation, differentiation, and survival, with isoform-specific effects on apoptosis suppression (isoform 1) and cell differentiation promotion (isoform 2). The protein interacts with various partners, including the cytoplasmic domain of ERBB3, and exhibits dynamic associations with AR, NCL/nucleolin, HDAC2, RB1, AKT1, RNF20, HUWE1, and DNAJC21, highlighting its versatility in engaging with diverse cellular components and participating in intricate molecular processes.
Gene ID
SwissProt ID
Synonyms
PA2G4; EBP1; Proliferation-associated protein 2G4; Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1
Molecular Weight

Predicted band size: 44 kDa; Observed band size: 48 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/40;FC: 1/50-1/100
Application

WB, IHC-P, ICC/IF, IP, FC
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human EBP1 / PA2G4
Database

Entrez Gene: 5036 Human ; 18813 Mouse ; 288778 Rat

SwissProt: Q9UQ80 Human ; P50580 Mouse ;

OMIM: 602145 Human

Documentation
User Guide for Antibodies (1077 KB)

EBP1 Antibody (YA2509) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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