1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. eIF4EBP3 Antibody (YA1080)

eIF4EBP3 Antibody (YA1080)

Cat. No.: HY-P81335
User Guide for Antibodies Technical Support

eIF4EBP3 Antibody (YA1080) is a non-conjugated IgG1 antibody, targeting 4E BP3, with a predicted molecular weight of 11 kDa (observed band size: 11 kDa). eIF4EBP3 Antibody (YA1080) can be used for WB experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
50 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μL Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

eIF4EBP3 Antibody (YA1080) is a non-conjugated IgG1 antibody, targeting 4E BP3, with a predicted molecular weight of 11 kDa (observed band size: 11 kDa). eIF4EBP3 Antibody (YA1080) can be used for WB experiment in human, mouse, rat background.

Background

EIF4EBP3 is a repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex. The hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to translation repression, whereas the hyperphosphorylated form dissociates from EIF4E, enabling EIF4G1/EIF4G3-EIF4E interaction and subsequent translation initiation (By similarity). It also inhibits EIF4E-mediated mRNA nuclear export.

Gene ID
SwissProt ID
Synonyms
4EBP3; 4E-BP3
Molecular Weight

Predicted band size: 11 kDa; Observed band size: 11 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human, Mouse, Rat

Dilution Ratio

WB: 1/500-1/1000

Application

WB

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Sensitivity

Transfected

Immunogen

Recombinant protein of human EIF4EBP3.

Database

Entrez Gene: 8637 Human

SwissProt: O60516 

OMIM: 603483 Human

Documentation

eIF4EBP3 Antibody (YA1080) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
eIF4EBP3 Antibody (YA1080)
Cat. No.:
HY-P81335
Quantity:
MCE Japan Authorized Agent: