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  5. CEBPB Antibody (YA1835)

CEBPB Antibody (YA1835)

Cat. No.: HY-P82090
COA
SDS
User Guide for Antibodies Technical Support

CEBPB Antibody (YA1835) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1835), targeting CEBPB, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). CEBPB Antibody (YA1835) can be used for WB, ICC/IF, IP, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

CEBPB Antibody (YA1835) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1835), targeting CEBPB, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). CEBPB Antibody (YA1835) can be used for WB, ICC/IF, IP, FC experiment in human, mouse, rat background.
Background

C/EBP Beta is a key transcription factor regulating genes involved in immune and inflammatory responses. It plays significant roles in adipogenesis, gluconeogenesis, liver regeneration, and hematopoiesis, with a consensus recognition site of 5'-T[TG]NNGNAA[TG]-3'. Its activity is modulated by protein interactions and post-translational modifications. During early embryogenesis, it shares redundant functions with CEBPA, promoting mitosis in hepatocytes and adipocytes while inhibiting T-cell proliferation by repressing MYC, thereby aiding T-helper 2 lineage differentiation. It binds regulatory regions of acute-phase and cytokine genes, influencing acute-phase reactions and inflammation. By similarity, it contributes to intracellular bacterial killing. In adipogenesis, it is rapidly expressed and, upon phosphorylation, induces CEBPA and PPARG to activate adipocyte phenotype-related genes. It is critical for ovarian follicle development (By similarity) and restricts osteoclastogenesis by repressing DSPP during odontoblast differentiation (By similarity). Essential for macrophage activation, it also drives immune responses like CD4(+) T-cell activation, granuloma formation, and endotoxin shock.
Gene ID
SwissProt ID
Synonyms
CEBPB; LAP; TCF5; PP9092; CCAAT/enhancer-binding protein beta; C/EBP beta; Liver activator protein; Nuclear factor NF-IL6; Transcription factor 5; TCF-5
Molecular Weight

Predicted band size: 36 kDa; Observed band size: 36 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
RRID
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100
Application

WB, ICC/IF, IP, FC
Appearance

Liquid
Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human CEBP Beta
Database

Entrez Gene: 1051 Human ; 12608 Mouse ; 24253 Rat

SwissProt: P17676 Human ; P28033 Mouse ; P21272 Rat

OMIM: 189965 Human

Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

CEBPB Antibody (YA1835) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CEBPB Antibody (YA1835)
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