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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

Cysteine protease

" in MedChemExpress (MCE) Product Catalog:

88

Inhibitors & Agonists

2

Screening Libraries

2

Fluorescent Dye

4

Biochemical Assay Reagents

14

Peptides

6

Natural
Products

11

Recombinant Proteins

1

Isotope-Labeled Compounds

19

Antibodies

Cat. No. Product Name
  • HY-L926
    Cysteine Protease Focused Covalent Library
    		2000 compounds

    Cysteine proteases (CPs), a key enzyme family regulating physiological metabolism and mediating pathological processes (e.g., abnormal bone resorption, tumour invasion, and pathogen infection), represent a core therapeutic target for disease intervention via the development of specific inhibitors. Currently reported CP covalent inhibitors encompass diverse structural types, including epoxides, aziridine, and activated double bonds (vinyl sulphones, α,β-unsaturated ketones), providing clear structural references for the development of novel CP covalent inhibitors.

    This compound library contains multiple warheads that specifically target cysteine proteases, serving as a powerful tool for the efficient discovery of novel covalent inhibitors against this enzyme family.

  • HY-L925
    Cysteine Protease Focused Library
    		9000 compounds

    Cysteine proteases (CPs), a key enzyme family regulating physiological metabolism and mediating pathological processes (such as abnormal bone resorption, tumour invasion, and pathogen infection), represent a core therapeutic target for developing specific inhibitors in disease intervention. Currently reported CP inhibitors primarily achieve their inhibitory function by precisely binding to CP active pockets (e.g., S1-S4 non-primed regions or S1'-S2' primed regions) and forming covalent/non-covalent interactions with the active site cysteine residues, providing clear structural references for the development of novel inhibitors.

    This compound library, designed based on the core strategy of "similarity-based known active structures", contains over 200 cysteine protease inhibitors. Leveraging AI-driven molecular screening technology, it retains the critical pharmacological and shape features of reported CP inhibitors, serving as a specialized tool for efficiently discovering novel cysteine protease inhibitors.

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