Trpv1 - transient receptor potential cation channel, subfamily V, member 1 Gene

Rattus norvegicus

Also known as Vr1; Vr1l1; VR.5'sv; TRPV1_SON

Gene ID: 83810 | Gene type: protein coding

About Trpv1

Summary

Enables several functions, including ATP binding activity; Calmodulin binding activity; and ligand-gated ion channel activity. Involved in several processes, including calcium ion import across plasma membrane; cellular response to organonitrogen compound; and cellular response to temperature stimulus. Acts upstream of or within response to heat and response to pH. Located in several cellular components, including external side of plasma membrane; neuronal cell body; and postsynaptic membrane. Is integral component of plasma membrane. Used to study myocardial infarction and reflex epilepsy. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1). [provided by Alliance of Genome Resources, Apr 2022]

Trpv1 Products(1)

mRNA	Protein	Name
NM_031982.1	NP_114188.1	transient receptor potential cation channel subfamily V member 1

Protein Preferred Names

Protein Names

transient receptor potential cation channel subfamily V member 1

OTRPC1	capsaicin receptor
deltaN-TRPV1	osm-9-like TRP channel 1
transient receptor potential vanilloid 1 supraoptic nucleus	vanilloid receptor 1
vanilloid receptor subtype 1	vanilloid receptor type 1 like protein 1
vanilloid type 1 receptor

Trpv1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Trpv1	O35433	dktx_cyrsc	Haplopelma schmidti	P0CH43	Pull Down	20510930
Intra	Trpv1	O35433	dktx_cyrsc	Haplopelma schmidti	P0CH43	3D-EM	27281200
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	Comig Non-Denat Gel	22575650
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	3D-EM	24305160
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	GMS	27281200
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	3D-EM	27281200
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	3D-EM	24305161
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	SLS	22575650
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	TEM	24305160
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	DLS	22575650
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	Crosslink	22575650
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	TEM	27281200
Intra	Trpv1	O35433	Trpv1	Rattus norvegicus	O35433	GMS	24305160

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Approval

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10448	Capsaicin		99.88%	Yes
HY-N0172	Caffeic acid	Inhibitor	99.92%	Unkown
HY-10448A	Capsaicin (Purity 65%)		99.20%	Unkown
HY-10448R	Capsaicin (Standard)		99.38%	Unkown
HY-17568	Nonivamide	Agonist	98.74%	Unkown
HY-B1583	(Z)-Capsaicin		99.79%	Yes
HY-B1173	(+)-Camphor	Inhibitor	≥98.0%	Unkown
HY-124073	Dihydrocapsiate	Agonist	99.33%	Unkown
HY-16413	Protokylol hydrochloride	Agonist	/	Unkown

Clinical Phase

Bioactive Molecules (15)

Cat. No.	Product Name	Effect	Purity	Phase
HY-N2333	Resiniferatoxin	Agonist	99.77%	Phase 3
HY-W020468	Linopirdine		99.90%	Phase 3
HY-12777	Asivatrep	Antagonist	95.76%	Phase 3
HY-132596	Tivanisiran	Inhibitor	92.62%	Phase 3
HY-105285	Piromelatine		99.54%	Phase 3
HY-10633	SB-705498	Antagonist	99.98%	Phase 2
HY-118785	MSP-3	Agonist	98.53%	Phase 2
HY-137459	Vocacapsaicin	Agonist	/	Phase 2
HY-12914	V116517	Antagonist	/	Phase 2
HY-137459A	Vocacapsaicin hydrochloride	Antagonist	/	Phase 2
HY-19589	JTS-653	Antagonist	/	Phase 2
HY-10634	AMG 517	Antagonist	99.97%	Phase 1
HY-N8377	Capsiate	Agonist	99.85%	Phase 1
HY-16935	Mavatrep	Antagonist	99.67%	Phase 1
HY-12195	ABT-239	Antagonist	99.23%	Phase 1

Pre-clinical Phase

Bioactive Molecules (110)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15640	Capsazepine		≥99.0%	Unkown
HY-10863	Anandamide		≥99.0%	Unkown
HY-N0285	Imperatorin		98.72%	Unkown
HY-101736	AMG9810	Antagonist	99.76%	Unkown
HY-12245	SB-366791	Antagonist	98.11%	Unkown
HY-N0361	Dihydrocapsaicin		99.93%	Unkown
HY-101507	Zerencotrep	Inhibitor	99.47%	Unkown
HY-N6825	Hydroxy-α-sanshool	Agonist	99.57%	Unkown
HY-19960	BCTC		99.66%	Unkown
HY-107436	LE135		≥99.0%	Unkown
HY-103368	Eact	Activator	98.86%	Unkown
HY-N0447	8-Gingerol		99.82%	Unkown
HY-157131	TRPV2-selective blocker 1	Inhibitor	99.84%	Unkown
HY-P3467	(Thr4,Gly7)-Oxytocin		99.86%	Unkown
HY-108448	N-Oleoyldopamine	Agonist	99.47%	Unkown
HY-101448	TMI-1		99.59%	Unkown
HY-18662	RQ-00203078	Antagonist	99.84%	Unkown
HY-N8264	Moringin	Agonist	99.95%	Unkown
HY-N1471	Liquiritin apioside		99.60%	Unkown
HY-N6962	α-Spinasterol		99.15%	Unkown
HY-108460	A-784168	Inhibitor	≥99.0%	Unkown
HY-100129	JNJ-17203212	Antagonist	99.94%	Unkown
HY-101323	Olvanil	Agonist	≥99.0%	Unkown
HY-121636	Resolvin D2	Inhibitor	99.90%	Unkown
HY-144372	TRPV1 antagonist 3	Antagonist	99.30%	Unkown
HY-132596A	Tivanisiran sodium		96.85%	Unkown
HY-120963	N-Oleoyl Taurine		≥99.0%	Unkown
HY-100668	JYL 1421	Antagonist	99.54%	Unkown
HY-120294	Chrysin 6-C-glucoside 8-C-arabinoside	Inhibitor	99.11%	Unkown
HY-136363	MDR-652	Agonist	99.02%	Unkown
HY-W014394	Vanillyl butyl ether	Agonist	99.67%	Unkown
HY-101389	(R)-Methanandamide	Agonist	/	Unkown
HY-110018	N-Arachidonyldopamine	Agonist	98.36%	Unkown
HY-114017	Libvatrep	Antagonist	99.54%	Unkown
HY-120962	N-Arachidonoyl Taurine	Activator	≥99.0%	Unkown
HY-160900	RN-1665	Antagonist	99.93%	Unkown
HY-108458	SB 452533	Antagonist	99.11%	Unkown
HY-10863S	Anandamide-d8		99.90%	Unkown
HY-109841	Oleoyl serotonin	Inhibitor	≥99.0%	Unkown
HY-12428	A-1165442	Antagonist	99.92%	Unkown
HY-135882	OMDM-6	Agonist	/	Unkown
HY-P1441A	Mambalgin 1 TFA	Inhibitor	95.72%	Unkown
HY-113654	AMG 7905	Antagonist	/	Unkown
HY-124001	N-Docosanoyl taurine	Activator	≥99.0%	Unkown
HY-131986	LASSBio-1135	Antagonist	99.05%	Unkown
HY-103337	N-Arachidonoylserotonin		≥98.0%	Unkown
HY-10635	ABT-102	Antagonist	/	Unkown
HY-108455	N-Palmitoyl dopamine		/	Unkown
HY-121636S	Resolvin D2-d5	Inhibitor	≥99.0%	Unkown
HY-N7536	Voacangine		98.78%	Unkown
HY-158110	Phenylcapsaicin	Activator	99.77%	Unkown
HY-10448S1	Capsaicin-d3		/	Unkown
HY-10448S4	Capsaicin-d7		/	Unkown
HY-108576	Linopirdine dihydrochloride	Agonist	/	Unkown
HY-110145	MRS 1477	Modulator	/	Unkown
HY-110292	A-425619	Antagonist	/	Unkown
HY-111036	AMG0347	Antagonist	/	Unkown
HY-111038	Capsiconiate	Agonist	/	Unkown
HY-111218	TRPV1 antagonist 5	Antagonist	/	Unkown
HY-114630	Protokylol	Agonist	/	Unkown
HY-120174	SU200		/	Unkown
HY-121080	AMG8163	Antagonist	/	Unkown
HY-124382	AS1928370		/	Unkown
HY-128479	JYL-273	Agonist	/	Unkown
HY-135881	OMDM-5	Agonist	/	Unkown
HY-137988	Palvanil	Modulator	/	Unkown
HY-147707	CB2 receptor antagonist 1		/	Unkown
HY-148751	TRPV1 activator-1	Activator	/	Unkown
HY-148752	TRPV1 activator-2	Activator	/	Unkown
HY-150030	CB1/2 agonist 4	Agonist	/	Unkown
HY-157766	FAAH/TRPV1 blocker-1	Inhibitor	/	Unkown
HY-161273	TRPV1 antagonist 6	Antagonist	/	Unkown
HY-161420	TRPV1 antagonist 7	Antagonist	/	Unkown
HY-162856	TRPV1-IN-2	Inhibitor	/	Unkown
HY-162908	TRPV1/CB2 agonist 1	Agonist	/	Unkown
HY-170839	TRPV1-IN-3	Inhibitor	/	Unkown
HY-172774	TRPV1 antagonist 10		/	Unkown
HY-176063	TRPV1 antagonist 11		/	Unkown
HY-N0361S	Dihydrocapsaicin-d3		/	Unkown
HY-N2941	Bisandrographolide C	Activator	/	Unkown
HY-P10464	Tat-AKAP79 (326-336)	Inhibitor	/	Unkown
HY-P10465	TRPV1-Tat	Antagonist	/	Unkown
HY-P1175	L-R4W2	Antagonist	/	Unkown
HY-P1175A	L-R4W2 TFA	Antagonist	/	Unkown
HY-RS15121	TRPV1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W517163	MK-2295	Antagonist	/	Unkown
HY-W654381	N-Vanillylnonanamide-d3		/	Unkown
HY-W790266	Polygodial pyridazine	Agonist	/	Unkown
HY-10635A	(S)-ABT-102	Antagonist	/	Unkown
HY-110091	TRPV1 antagonist 9	Antagonist	/	Unkown
HY-110209	AC4	Antagonist	/	Unkown
HY-117683	BCTP	Antagonist	/	Unkown
HY-117922	JYL-79	Agonist	/	Unkown
HY-120476	JNJ-39729209	Inhibitor	/	Unkown
HY-121122	A778317	Antagonist	/	Unkown
HY-121465	Stearoyl Serotonin		/	Unkown
HY-123374	(Rac)-AMG 628	Antagonist	/	Unkown
HY-123428	MSK-195	Agonist	/	Unkown
HY-133166	A-889425	Antagonist	/	Unkown
HY-167868	DWP-05195		/	Unkown
HY-16935S	Mavatrep-d6	Antagonist	/	Unkown
HY-169780	(S)-AMG-628	Antagonist	/	Unkown
HY-N10612	Petasin		/	Unkown
HY-P10654	RhTx	Activator	/	Unkown
HY-RS16501	Trpv1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22933	Trpv1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W554764	Cyclo(-asp-gly)	Activator	/	Unkown
HY-W708469	Resolvin D2 methyl ester	Inhibitor	/	Unkown
HY-W747573	N-Linolenoylethanolamine	Agonist	/	Unkown
HY-W931056	AMG-628	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Trpv1	NCBI	NCBI:7442

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